The Society of Hospital Medicine welcomes its newest members:

Kwie-Hoa Siem, MD, Alaska

Frank Abene, Alabama

Kayla Maldonado, Alabama

Kenny Murray, MD, Alabama

Shanthan Ramidi, MD, Alabama

Lauren Hancock, APRN, Arkansas

William Hawkins, MD, Arkansas

Matthew Law, Arkansas

Emily Smith, MD, Arkansas

Firas Abbas, MBchB, Arizona

Shahid Ahmad, MD, MBBS, Arizona

Praveen Bheemanathini, Arizona

Atoosa Hosseini, Arizona

William McGrade, DO, Arizona

Konstantin Mazursky, DO, Arizona

Ibrahim Taweel, MD, Arizona

Kevin Virk, MD, FACP, Arizona

Kevin Virk, MD, FACP, Arizona

Mohemmedd Khalid Abbas, Arizona

Hasan Chaudhry, MD, Arizona

Kelly Kelleher, FAAP, Arizona

Priyanka Sultania Dudani, MBBS, Arizona

Krishna Kasireddy, MD, Arizona

Melanie Meguro, Arizona

Puneet Tuli, MD, Arizona

Jonathan Byrdy, DO, Arizona

Sarah Corral, DO, Arizona

Edward Maharam, MD, Arizona

Arvind Satyanarayan, DO, Arizona

Mayank Aggarwal, MD, Arizona

Syed Jafri, Arizona

Bujji Ainapurapu, MD, Arizona

Aaron Fernandes, MD, Arizona

Sonal Gandhi, Arizona

Sudhir Tutiki, Arizona

Navaneeth Kumar, MD, Arizona

Brian T. Courtney, MD, California

Won Jin Jeon, California

Veena Panduranga, MD, California

Jennifer Tinloy, DO, California

Debra Buckland Coffey, MCUSN, MD, California

Kathleen Teves, MD, California

Paul Goebel, MD, ACMPE, California

Shainy Hegde, California

Summaiya Muhammad, California

Desmond Wah, California

Chonn Khristin Ng, California

Almira Yang, DO, California

Salimah Boghani, MD, California

Stella Abhyankar, California

Cherie Ginwalla, MD, California

Armond Esmaili, California

Sarah Schaeffer, MD, MPH, California

Sophia Virani, MD, California

Dipti Munshi, MD, California

Judy Nguyen, DO, California

Daniel Owyang, DO, California

Christian Chiavetta, DO, California

David Reinert, DO, California

Joseph Pawlowski, MD, California

Eleanor Yang, California

Adrian Campo, MD, California

Emerson De Jesus, MD, California

Zachary Edmonds, MD, California

Trit Garg, California

Alexandra G. Ianculescu, MD, PhD, California

Felix Karp, MD, California

Cara Lai, California

Kristen Lew, MD, California

John Mogannam, California

Ameer Moussa, California

Neil Parikh, MD, MBA, California

Priya Reddy, California

Adam Simons, California

Sanjay Vadgama, MD, California

Kristofer Wills, DO, California

Michael Yang, MD, MS, California

Victor Ekuta, California,

Donna Colobong, PA-C, Colorado

Janna B. Dreason, FNP-C, Colorado

Cheryl English, NP-C, Colorado

Melanie Gerrior, MD, Colorado

Marciann Harris, NP, Colorado

Marsha Henke, MD, Colorado

Brett Hesse, Colorado

Naomi J Hipp, MD, Colorado

Aurell Horing, Colorado

Rachel Koch, DO, Colorado

Ed Marino, PA-C, Colorado

Marcus Reinhardt, MD, Colorado

Carol Runge, Colorado

Harshal Shah, Colorado

Leo Soehnlen, DO, Colorado

Anna Villalobos, MD, Colorado

Kathryn Whitfield, PA-C, Colorado

Jonathan Bei-Shing Young, MD, Colorado

Leah Damiani, MD, Colorado

Kathy Lynch, MD, Colorado

Micah Friedman, Colorado

Rachael Hilton, MD, Colorado

Madeline Koerner, Colorado

Chi Zheng, MD, Colorado

Chin-Kun Baw, MD, Connecticut

Alexandra Hawkins, NP, Connecticut

Vasundhara Singh, MD, MBBS, Connecticut

Ryan Quarles, MD, Connecticut

Debra Hernandez, APRN, BC, Connecticut

Karine Karapetyan, MD, Delaware

Choosak Burr, ARNP, Florida

Nelsi Mora, Florida

Mary Quillinan, Florida

Thuntanat Rachanakul, Florida

Samual W. Sauer, MD, MPH, Florida

Jennifer Tibangin, Florida

Keith Williams, MD, Florida

Eric Penedo, MD, Florida

Margaret Webb, Florida

Mark Bender, Florida

Brett Waress, MD, MHA, Florida

Giselle Racho, Florida

Bryan Thiel, Florida

Juan Loor Tuarez, MD, Florida

Christine Stopyra, Florida

Betsy Screws, ARNP, Florida

Jaimie Weber, MD, Florida

Priti Amin, MHA, Georgia

Naga Doddapaneni, Georgia

Stephanie Fletcher, Georgia

Disha Spath, MD, Georgia

Rafaela Wesley, DO, Georgia

Nikky Keer, DO, Georgia

James Kim, Georgia

Todd Martin, Georgia

Eli Mlaver, Georgia

Andrew Ritter, Georgia

Ali Al-Zubaidi, MBchB, Georgia

Deann Bing, MD, Georgia

Tushar Shah, Georgia

Cameron Straughn, DO, Georgia

Nobuhiro Ariyoshi, MEd, Hawaii

Prerna Kumar, Iowa

Jonathan Sebolt, MD, Iowa

Amy Tesar, DO, Iowa

Houng Chea, NP, Idaho

Finnegan Greer, PA-C, Idaho

Thao Nelson, PA, Idaho

Malatesha Gangappa, Idaho

Gloria Alumona, ACNP, Illinois

Ram Sanjeev Alur, Illinois

James Antoon, MD, FAAP, PhD, Illinois

Stefania Bailuc, MD, Illinois

Richard Huh, Illinois

Bhakti Patel, MD, Illinois

Frances Uy, ACNP, Illinois

Fernando Velazquez Vazquez, MD, Illinois

Tiffany White, MD, Illinois

Bryan P. Tully, MD, Illinois

Swati Gobhil, MBBS, Illinois

Lianghe Gao, Illinois

Gopi Astik, MD, Illinois

Marina Kovacevic, MD, Illinois

Abbie Raymond, DO, Illinois

Timothy Yung, Illinois

Ahmed Zahid, MD, Illinois

Cristina Corsini, MEd, Illinois

Faisal Rashid, MD, FACP, Illinois

Mansoor Ahmad, MD, Illinois

Matthew A. Strauch, DO, Illinois

Purshotham Reddy Grinne, Illinois

Nadia Nasreen, MD, Illinois

Maham Ashraf, MD, Indiana

Jennifer Gross, Indiana

Debasmita Mohapatra, MBBS, Indiana

Eric Scheper, Indiana

Katherine Gray, APRNBC, FNP, Indiana

Venkata Kureti, Indiana

Omer Al-Buoshkor, MD, Indiana

David Johnson, FNP, MSN, Indiana

Jonathan Salisbury, MD, Indiana

Debra Shapert, MSN, RN, Iowa

Lisa Carter, ARNP, Iowa

Matthew Woodham, Iowa

Tomoharu Suzuki, MD, Pharm, Japan

Khaldoun Haj, Kansas

Will Rogers, ACMPE, MA, MBA, Kansas

Karen Shumate, Kansas

Lisa Unruh, MD, Kansas

Matthew George, Kansas

Katie Washburn, DO, Kansas

Edwin Avallone, DO, Kentucky

Matthew Morris, Kentucky

Samantha Cappetto, MD, Kentucky

Jaison John, Kentucky

Ammar Al Jajeh, Kentucky

Joseph Bolger, MD, PhD, Louisiana

Clairissa Mulloy, Louisiana

Harish Talla, MD, Louisiana

John Amadon, Louisiana

Karthik Krishnareddy, Louisiana

Cheryl DeGrandpre, PA-C, Maine

Katherine Liu, MD, Maine

Sarah Sedney, MD, Maine

Aksana Afanasenka, MD, Maryland

Syed Nazeer Mahmood, MBBS, Maryland

Joseph Apata, MD, Maryland

Russom Ghebrai, MD, Maryland

Musa Momoh, MD, Maryland

Antanina Voit, Maryland

Dejene Kassaye, MD, MSC, Maryland

Shams Quazi, MD, FACP, MS, Maryland

Dawn Roelofs, FNP, MSN, Maryland

Kirsten Austad, MD, Massachusetts

Yoel Carrasquillo Vega, MD, Massachusetts

Michele Gaudet, NP, Massachusetts

Karina Mejias, Massachusetts

Peter Rohloff, MD, PhD, Massachusetts

Jennifer Schaeffer, Massachusetts

James Shaw, MD, Massachusetts

Renee Wheeler, Massachusetts

Angela Freeman, PA, PA-C, Massachusetts

Supriya Parvatini, MD, Massachusetts

Karen Jiang, MD, Massachusetts

Roula E. Abou-Nader, MD, Massachusetts

Shreekant Vasudhev, MD, Massachusetts

Nivedita Adabala, MD, MBBS, Michigan

Robert Behrendt, RN, BSN, Michigan

Molly Belisle, Michigan

Christine Dugan, MD, Michigan

Baljinder Gill, Michigan

Kellie Herringa, PA-C, Michigan

Christine Klingert, Michigan

Kathy Mitchell, Michigan

Aimee Vos, Michigan

Alyssa Churchill, DO, Michigan

Mailvaganam Sridharan, MD, Michigan

Atul Kapoor, MD, MBBS, Michigan

Anitha Kompally, MD, MBBS, Michigan

Nicole Webb, PA-C, Michigan

Abdulqadir Ahmad, MD, Minnesota

John Patrick Eikens, Minnesota

Bobbi Jo Jensen, PA-C, Minnesota

Rachel Keuseman, Minnesota

Stephen Palmquist, Minnesota

Manit Singla, MD, Minnesota

Douglas Berg, Minnesota

Nathan Palmolea, Minnesota

Molly Tureson, PAC, Minnesota

Mehdi Dastrange, MD, MHA, Minnesota

Kent Svee, Minnesota

Ashley Viere, PA-C, Minnesota

Molly Yang, MD, Minnesota

Paige Sams, DO, Minnesota

Amit Reddy, MBBS, Mississippi

Jacqueline Brooke Banks, FNP-C, Mississippi

Lori Foxworth, CFNP, Mississippi

Nicki Lawson, FNP-C, Mississippi

Bikash Acharya, Missouri

Zafar Ahmad, PA-C, Missouri

Harleen Chela, MD, Missouri

Jeffrey Chung, MD, Missouri

Daniel Kornfeld, Missouri

Erika Leung, MD, MSc, Missouri

Lisa Moser, PA, Missouri

Mark Stiffler, Missouri

Tushar Tarun, MBBS, Missouri

Nicole McLaughlin, Missouri

Katy Lohmann, PA-C, Missouri

Jayasree Bodagala, MD, Missouri

Ravi Kiran Morumuru, ACMPE, Missouri

Matthew Brown, MD, FAAFP, Missouri

Ravikanth Tadi, Missouri

Bazgha Ahmad, DO, Missouri

Monica Hawkins, RN, Missouri

Karri Vesey, BSN, Montana

Madison Vertin, PA-C, Montana

Urmila Mukherjee, MD, Nebraska

Noah Wiedel, MD, Nebraska

Sidrah Sheikh, MD, MBBS, Nebraska

Mohammad Esmadi, MBBS, Nebraska

Jill Zabih, MD, Nebraska

Jody Frey-Burns, RN, Nevada

Adnan Akbar, MD, Nevada

Peter Gayed, MRCP, New Hampshire

Jonathan T. Huntington, MD, New Hampshire

Meghan Meehan, ACNP, New Hampshire

Saurabh Mehta, MD, New Jersey

Hanaa Benchekroun Belabbes, MD, MHA, New Jersey

Hwan Kim, MD, New Jersey

Mary Tobiasson, USA, New Jersey

Muhammad Khakwani, MD, New Jersey

Amita Maibam, MD, MPH, New Jersey

Kumar Rohit, MBBS, New Jersey

Crystal Benjamin, MD, New Jersey

Rafael Garabis, New Mexico

Sam MacBride, MD, New Mexico

Indra Peram, MD, New Mexico

Sarah Vertrees, DO, New Mexico

Aswani Kumar Alavala, MD, New Mexico

Christopher Anstine, New Mexico

Prathima Guruguri, MD, New Mexico

Diedre Hofinger, MD, FACP, New Mexico

Katharine Juarez, New Mexico

Amtul Mahavesh, MD, New Mexico

Francisco Marquez, New Mexico

Payal Sen, MD, New Mexico

Morgan Wong, DO, New Mexico

Kelly Berchou, New York

Ronald Cho, New York

Nishil Dalsania, New York

Carolyn Drake, MD, MPH, New York

Leanne Forman, New York

Valerie Gausman, New York

Laurie Jacobs, New York

Janice Jang, MD, New York

Sonia Kohli, MD, New York

Nancy Lee, PA, New York

Allen Lee, MD, New York

Matthew McCarthy, FACP, New York

Akram Mohammed, MD, New York

Jennifer Nead, New York

Kristal Persaud, PA, New York

Mariya Rozenblit, MD, New York

Christian Torres, MD, New York

Sasha De Jesus, MD, New York

Gabriella Polyak, New York

Nataliya Yuklyaeva, MD, New York

Riyaz Kamadoli, MD, New York

Ramanuj Chakravarty, New York

Adil Zaidi, MD, New York

Allison Walker, MD, New York

Himali Gandhi, New York

Alexey Yanilshtein, MD, New York

Ramsey Al-Khalil, New York

Latoya Codougan, MD, New York

Khan Najmi, MD, New York

Sara Stream, MD, New York

Bhuwan Poudyal, MD, New York

Khalil Anchouche, New York

Sarah Azarchi, New York

Susana Bejar, New York

Brian Chang, New York

Jonathan Chen, New York

Hailey Gupta, MD, New York

Medhavi Gupta, New York

Ali Khan, New York

Benjamin Kwok, MD, New York

Billy Lin, New York

Katherine Ni, New York

Jina Park, New York

Gabriel Perreault, New York

Luis Alberto Romero, New York

Payal Shah, New York

Punita Shroff, New York

Scott Statman, New York

Maria Sunseri, New York

Benjamin Verplanke, New York

Audrey Zhang, New York

Gaby Razzouk, MD, New York

Pranitha Mantrala, MD, New York

Marsha Antoine, New York

Kanica Yashi, New York

Navid Ahmed, New York

Tasha Richards, PA, New York

Connor Tryon, MD, New York

Naveen Yarlagadda, MD, New York

Alex Hogan, New York

Andrew Donohoe, CCM, MD, North Carolina

Brittany Forshay, MD, North Carolina

Kelly Hammerbeck, FNP, North Carolina

Jennifer Hausman, North Carolina

Babajide Obisesan, North Carolina

Kwadwo Ofori, MD, North Carolina

Eric Ofosu, MD, North Carolina

Kale Roth, North Carolina

Robert Soma, PA-C, North Carolina

Sommany Weber, North Carolina

Ronnie Jacobs, North Carolina

Muhammad Ghani, MD, MACP, MBBS, North Carolina

Madeline Treasure, North Carolina

Andrew McWilliams, MD, North Carolina

Karen Payne, ACNP, MPH, North Carolina

Rafal Poplawski, MD, North Carolina

James Seal, PA-C, North Carolina

Farheen Qureshi, DO, North Carolina

Basavatti Sowmya, MD, MBBS, North Carolina

Eshwar Lal, MD, North Carolina

Catherine Hathaway, MD, North Carolina

Sherif Naguib, FAAFP, North Carolina

Sara Skavroneck, North Carolina

Charles Ofosu, North Carolina

Alex Alburquerque, MD, Ohio

Isha Butler, DO, Ohio

Anne Carrol, MD, Ohio

Scott Childers, MD, Ohio

Philip Jonas, MD, Ohio

Ahmadreza Karimianpour, Ohio

Rahul Kumar, MD, Ohio

George Maidaa, MD, Ohio

Kevin McAninch, Ohio

Jill Mccourt, FNP, Ohio

Roxanne Oliver, Ohio

Farah Hussain, Ohio

Natasha Axton, PA-C, Ohio

Brooke Harris, ACNP, Ohio

Vidhya Murukesan, MD, Ohio

Sara Dong, Ohio

Christie Astor, FNP, Ohio

Sunita Mall, MD, Ohio

Sunita Mall, MD, Ohio

Fouzia Tariq, MD, Ohio

Kaveri Sivaruban, MD, Ohio

Eunice Quicho, Ohio

Smitha Achuthankutty, MD, Ohio

Harmanpreet Shinh, MD, Ohio

Maereg Tesfaye, Ohio

Kalyn Jolivette, MD, Ohio

Richelle Voth, PA-C, Oklahoma

Samuel J. Ratermann, MD, FAAFP, Oklahoma

Richelle Voth, PA-C, Oklahoma

Alden Forrester, MD, Oregon

Nicholas Brown, DO, Oregon

Ian Pennell-Walklin, MD, Oregon

Bruce Ramsey, Oregon

Kyle Brekke, DO, Oregon

Sarah Webber, MD, Oregon

Brian Beaudoin, MD, Pennsylvania

Glenn Bedell, MHSA, Pennsylvania

Cristina Green, AGACNP-DNP, Pennsylvania

Andrew Groff, Pennsylvania

Sulman Masood Hashmi, MBBS, Pennsylvania

Eric Kasprowicz, MD, MPH, Pennsylvania

Laura Leuenberger, Pennsylvania

James Liszewski, MD, Pennsylvania

Caitlyn Moss, Pennsylvania

Paul Seunghyun Nho, Pennsylvania

Rishan Patel, MD, Pennsylvania

Dilli R. Poudel, MBBS, Pennsylvania

Naveen Yellappa, MBBS, Pennsylvania

Usman Zulfiqar, Pennsylvania

Nina Jain, Pennsylvania

Bhumika Patel, DO, Pennsylvania

Jenna M. Diasio, PA-C, Pennsylvania

Malachi Courtney, MD, Pennsylvania

Sonia Arneja, MD, Pennsylvania

Ross Ellis, MD, Pennsylvania

Samreen Siddiqui, Pennsylvania

Jillian Zavodnick, Pennsylvania

Kinan Kassar, MD, Pennsylvania

Maritsa M. Scoulos-Hanson, Pennsylvania

Jennifer Taylor, PA-C, Pennsylvania

Steven Delaveris, DO, Pennsylvania

Danica Buzniak, DO, Rhode Island

Paul Browning, MD, South Carolina

Matt Coones, MD, South Carolina

Cedric Fisher, MD, South Carolina

Aloysius Jackson, MD, South Carolina

Katharine DuPont, MD, South Carolina

Michael Jenkins, MD, South Carolina

Jessica Hamilton, APRN, BC, FNP, South Carolina

Pamela Pyle, DO, South Carolina

Shakeel Ahmed, MBBS, MD, South Dakota

D. Bruce Eaton, MD, South Dakota

Drew Jorgensen, MD, South Dakota

Shelly Turbak, MSN, RN, South Dakota

Tamera Sturm, DO, South Dakota

Peggy Brooks, Tennessee

Joseph Garrido, MD, Tennessee

Lisa Grimes, FNP, Tennessee

Chennakesava Kummathi, MBBS, Tennessee

Victoria Okafor, Tennessee

Ashley Smith, Tennessee

Monisha Bhatia, Tennessee

Belinda Jenkins, APRN-BC, Tennessee

Kim Zahnke, MD, Tennessee

Robert Arias, Texas

Nicolas Batterton, MD, Texas

Scott DePaul, MD, Texas

Nancy Foster, Texas

Larry Hughes, Texas

Erin Koval, Texas

Femi Layiwola, MD, Texas

Krysta Lin, Texas

James J. Onorato, MD, PhD, Texas

Allison Stephenson, PA-C, Texas

Brandon Stormes, Texas

Rubin Simon, MD, Texas

Brian Anderson, DO, Texas

Hatim Chhatriwala, MD, Texas

Aziz Hammoud, Texas

Haru Yamamoto, MD, Texas

Lauren Schiegg, Texas

Victoria Grasso, DO, Texas

Victor Salcedo, MD, Texas

Rajiv Bhattarai, Texas

Iram Qureshi, DO, Texas

Lisa Hafemeister, FACHE, MHA, Texas

Helena Kurian, MD, Texas

Jessica Lin, Texas

Nathan Nowalk, MD, Texas

Keely Smith, MD, Texas

Jonathan Weiser, MD, Texas

Roland Prezas, DO, FAAFP, Texas

Allan Recto, AHIP, Texas

Regina Dimbo, Texas

Venkata Ghanta, Texas

Richmond Hunt, Texas

Vishal Patel, MD, Texas

Zain Sharif, MD, Texas

Rommel Del Rosario, MD, Texas

Khawer Khadimally, DO, Texas

Diogenes Valderrama, MD, Texas

Charles Ewoh, MD, Texas

Deepika Kilaru, Texas

Tilahun Belay, MD, Texas

Chandra S Reddy Navuluri, MD, Texas

Bradley Goad, DO, FACP, Virginia

Patrick Higdon, MD, Virginia

Gabriella Miller, MD, HMDC, Virginia

Miklos Szentirmai, MD, Virginia

Hyder Tamton, Virginia

Andra Mirescu, MD, Virginia

Olukayode Ojo, Virginia

Robert Szeles, MD, Virginia

Anya Cope, DO, Virginia

OsCiriah Press, MD, Virginia

Rikin Kadakia, MD, Virginia

Bryant Self, DO, Virginia

Sarah Sabo, ACNP, Virginia

Pedro A. Gonzales Alvarez, MD, Virginia

William Best, Virginia

Pushpanjali Basnyat, MD, Washington

Nikki Hartley-Jonason, Washington

Helen Johnsonwall, MD, Washington

Eric LaMotte, MD, Washington

Maher Muraywid, Washington

Evan Neal Paul, MD, Washington

Sarah Rogers, MD, Washington

Lindee Strizich, Washington

Maryam Tariq, MBBS, Washington

Meghaan Walsh, MD, Washington

Oleg Zbirun, MD, Washington

Meeta Sabnis, MD, Washington

James Kuo, MD, Washington

Liang Du, Washington

Syed Farhan Tabraiz Hashmi, MD, Washington

Jessica Jung, MD, Washington

Joshua Pelley, MD, Washington

Alex Yu, MD, Washington

Alfred Curnow, MD, Washington

Duhwan Kang, Washington

Gilbert Daniel, MD, Washington, D.C.

Eleanor Fitall, Washington, D.C.

Vinay Srinivasan, Washington, D.C.

Scott Wine, West Virginia

Trevor Miller, MBA, PA-C, West Virginia

Audrey Hiltunen, Wisconsin

Elina Litinskaya, Wisconsin

John M. Murphy, MD, Wisconsin

Tanya Pedretti, PA, Wisconsin

Adine Rodemeyer, MD, Wisconsin

Oghomwen Sule, MBBS, Wisconsin

Terrence Witt, MD, Wisconsin

Mayank Arora, Wisconsin

John D. MacDonald, MD, Wisconsin

Abigail Cook, Wisconsin

Mohamed Ibrahim, MD, Wisconsin

Aymen Khogali, MD, Wisconsin

Nicholas Haun, Wisconsin

Sandra Brown, Victoria, Australia

Alessandra Gessner, Alberta, Canada

Courtney Carlucci, British Columbia, Canada

Muhanad Y. Al Habash, Canada

Karen Tong, MD, Canada

Taku Yabuki, Japan

Liza van Loon, the Netherlands

Edward Gebuis, MD, the Netherlands

Abdisalan Afrah, MD, Qatar

Akhnuwkh Jones, Qatar

Mashuk Uddin, MBBS, MRCP, FRCP, Qatar

Ibrahim Yusuf Abubeker, MRCP, Qatar

Chih-Wei Tseng, Taiwan

Sawsan Abdel-Razig, MD, FACP, United Arab Emirates

The Society of Hospital Medicine welcomes its newest members:

Kwie-Hoa Siem, MD, Alaska

Frank Abene, Alabama

Kayla Maldonado, Alabama

Kenny Murray, MD, Alabama

Shanthan Ramidi, MD, Alabama

Lauren Hancock, APRN, Arkansas

William Hawkins, MD, Arkansas

Matthew Law, Arkansas

Emily Smith, MD, Arkansas

Firas Abbas, MBchB, Arizona

Shahid Ahmad, MD, MBBS, Arizona

Praveen Bheemanathini, Arizona

Atoosa Hosseini, Arizona

William McGrade, DO, Arizona

Konstantin Mazursky, DO, Arizona

Ibrahim Taweel, MD, Arizona

Kevin Virk, MD, FACP, Arizona

Kevin Virk, MD, FACP, Arizona

Mohemmedd Khalid Abbas, Arizona

Hasan Chaudhry, MD, Arizona

Kelly Kelleher, FAAP, Arizona

Priyanka Sultania Dudani, MBBS, Arizona

Krishna Kasireddy, MD, Arizona

Melanie Meguro, Arizona

Puneet Tuli, MD, Arizona

Jonathan Byrdy, DO, Arizona

Sarah Corral, DO, Arizona

Edward Maharam, MD, Arizona

Arvind Satyanarayan, DO, Arizona

Mayank Aggarwal, MD, Arizona

Syed Jafri, Arizona

Bujji Ainapurapu, MD, Arizona

Aaron Fernandes, MD, Arizona

Sonal Gandhi, Arizona

Sudhir Tutiki, Arizona

Navaneeth Kumar, MD, Arizona

Brian T. Courtney, MD, California

Won Jin Jeon, California

Veena Panduranga, MD, California

Jennifer Tinloy, DO, California

Debra Buckland Coffey, MCUSN, MD, California

Kathleen Teves, MD, California

Paul Goebel, MD, ACMPE, California

Shainy Hegde, California

Summaiya Muhammad, California

Desmond Wah, California

Chonn Khristin Ng, California

Almira Yang, DO, California

Salimah Boghani, MD, California

Stella Abhyankar, California

Cherie Ginwalla, MD, California

Armond Esmaili, California

Sarah Schaeffer, MD, MPH, California

Sophia Virani, MD, California

Dipti Munshi, MD, California

Judy Nguyen, DO, California

Daniel Owyang, DO, California

Christian Chiavetta, DO, California

David Reinert, DO, California

Joseph Pawlowski, MD, California

Eleanor Yang, California

Adrian Campo, MD, California

Emerson De Jesus, MD, California

Zachary Edmonds, MD, California

Trit Garg, California

Alexandra G. Ianculescu, MD, PhD, California

Felix Karp, MD, California

Cara Lai, California

Kristen Lew, MD, California

John Mogannam, California

Ameer Moussa, California

Neil Parikh, MD, MBA, California

Priya Reddy, California

Adam Simons, California

Sanjay Vadgama, MD, California

Kristofer Wills, DO, California

Michael Yang, MD, MS, California

Victor Ekuta, California,

Donna Colobong, PA-C, Colorado

Janna B. Dreason, FNP-C, Colorado

Cheryl English, NP-C, Colorado

Melanie Gerrior, MD, Colorado

Marciann Harris, NP, Colorado

Marsha Henke, MD, Colorado

Brett Hesse, Colorado

Naomi J Hipp, MD, Colorado

Aurell Horing, Colorado

Rachel Koch, DO, Colorado

Ed Marino, PA-C, Colorado

Marcus Reinhardt, MD, Colorado

Carol Runge, Colorado

Harshal Shah, Colorado

Leo Soehnlen, DO, Colorado

Anna Villalobos, MD, Colorado

Kathryn Whitfield, PA-C, Colorado

Jonathan Bei-Shing Young, MD, Colorado

Leah Damiani, MD, Colorado

Kathy Lynch, MD, Colorado

Micah Friedman, Colorado

Rachael Hilton, MD, Colorado

Madeline Koerner, Colorado

Chi Zheng, MD, Colorado

Chin-Kun Baw, MD, Connecticut

Alexandra Hawkins, NP, Connecticut

Vasundhara Singh, MD, MBBS, Connecticut

Ryan Quarles, MD, Connecticut

Debra Hernandez, APRN, BC, Connecticut

Karine Karapetyan, MD, Delaware

Choosak Burr, ARNP, Florida

Nelsi Mora, Florida

Mary Quillinan, Florida

Thuntanat Rachanakul, Florida

Samual W. Sauer, MD, MPH, Florida

Jennifer Tibangin, Florida

Keith Williams, MD, Florida

Eric Penedo, MD, Florida

Margaret Webb, Florida

Mark Bender, Florida

Brett Waress, MD, MHA, Florida

Giselle Racho, Florida

Bryan Thiel, Florida

Juan Loor Tuarez, MD, Florida

Christine Stopyra, Florida

Betsy Screws, ARNP, Florida

Jaimie Weber, MD, Florida

Priti Amin, MHA, Georgia

Naga Doddapaneni, Georgia

Stephanie Fletcher, Georgia

Disha Spath, MD, Georgia

Rafaela Wesley, DO, Georgia

Nikky Keer, DO, Georgia

James Kim, Georgia

Todd Martin, Georgia

Eli Mlaver, Georgia

Andrew Ritter, Georgia

Ali Al-Zubaidi, MBchB, Georgia

Deann Bing, MD, Georgia

Tushar Shah, Georgia

Cameron Straughn, DO, Georgia

Nobuhiro Ariyoshi, MEd, Hawaii

Prerna Kumar, Iowa

Jonathan Sebolt, MD, Iowa

Amy Tesar, DO, Iowa

Houng Chea, NP, Idaho

Finnegan Greer, PA-C, Idaho

Thao Nelson, PA, Idaho

Malatesha Gangappa, Idaho

Gloria Alumona, ACNP, Illinois

Ram Sanjeev Alur, Illinois

James Antoon, MD, FAAP, PhD, Illinois

Stefania Bailuc, MD, Illinois

Richard Huh, Illinois

Bhakti Patel, MD, Illinois

Frances Uy, ACNP, Illinois

Fernando Velazquez Vazquez, MD, Illinois

Tiffany White, MD, Illinois

Bryan P. Tully, MD, Illinois

Swati Gobhil, MBBS, Illinois

Lianghe Gao, Illinois

Gopi Astik, MD, Illinois

Marina Kovacevic, MD, Illinois

Abbie Raymond, DO, Illinois

Timothy Yung, Illinois

Ahmed Zahid, MD, Illinois

Cristina Corsini, MEd, Illinois

Faisal Rashid, MD, FACP, Illinois

Mansoor Ahmad, MD, Illinois

Matthew A. Strauch, DO, Illinois

Purshotham Reddy Grinne, Illinois

Nadia Nasreen, MD, Illinois

Maham Ashraf, MD, Indiana

Jennifer Gross, Indiana

Debasmita Mohapatra, MBBS, Indiana

Eric Scheper, Indiana

Katherine Gray, APRNBC, FNP, Indiana

Venkata Kureti, Indiana

Omer Al-Buoshkor, MD, Indiana

David Johnson, FNP, MSN, Indiana

Jonathan Salisbury, MD, Indiana

Debra Shapert, MSN, RN, Iowa

Lisa Carter, ARNP, Iowa

Matthew Woodham, Iowa

Tomoharu Suzuki, MD, Pharm, Japan

Khaldoun Haj, Kansas

Will Rogers, ACMPE, MA, MBA, Kansas

Karen Shumate, Kansas

Lisa Unruh, MD, Kansas

Matthew George, Kansas

Katie Washburn, DO, Kansas

Edwin Avallone, DO, Kentucky

Matthew Morris, Kentucky

Samantha Cappetto, MD, Kentucky

Jaison John, Kentucky

Ammar Al Jajeh, Kentucky

Joseph Bolger, MD, PhD, Louisiana

Clairissa Mulloy, Louisiana

Harish Talla, MD, Louisiana

John Amadon, Louisiana

Karthik Krishnareddy, Louisiana

Cheryl DeGrandpre, PA-C, Maine

Katherine Liu, MD, Maine

Sarah Sedney, MD, Maine

Aksana Afanasenka, MD, Maryland

Syed Nazeer Mahmood, MBBS, Maryland

Joseph Apata, MD, Maryland

Russom Ghebrai, MD, Maryland

Musa Momoh, MD, Maryland

Antanina Voit, Maryland

Dejene Kassaye, MD, MSC, Maryland

Shams Quazi, MD, FACP, MS, Maryland

Dawn Roelofs, FNP, MSN, Maryland

Kirsten Austad, MD, Massachusetts

Yoel Carrasquillo Vega, MD, Massachusetts

Michele Gaudet, NP, Massachusetts

Karina Mejias, Massachusetts

Peter Rohloff, MD, PhD, Massachusetts

Jennifer Schaeffer, Massachusetts

James Shaw, MD, Massachusetts

Renee Wheeler, Massachusetts

Angela Freeman, PA, PA-C, Massachusetts

Supriya Parvatini, MD, Massachusetts

Karen Jiang, MD, Massachusetts

Roula E. Abou-Nader, MD, Massachusetts

Shreekant Vasudhev, MD, Massachusetts

Nivedita Adabala, MD, MBBS, Michigan

Robert Behrendt, RN, BSN, Michigan

Molly Belisle, Michigan

Christine Dugan, MD, Michigan

Baljinder Gill, Michigan

Kellie Herringa, PA-C, Michigan

Christine Klingert, Michigan

Kathy Mitchell, Michigan

Aimee Vos, Michigan

Alyssa Churchill, DO, Michigan

Mailvaganam Sridharan, MD, Michigan

Atul Kapoor, MD, MBBS, Michigan

Anitha Kompally, MD, MBBS, Michigan

Nicole Webb, PA-C, Michigan

Abdulqadir Ahmad, MD, Minnesota

John Patrick Eikens, Minnesota

Bobbi Jo Jensen, PA-C, Minnesota

Rachel Keuseman, Minnesota

Stephen Palmquist, Minnesota

Manit Singla, MD, Minnesota

Douglas Berg, Minnesota

Nathan Palmolea, Minnesota

Molly Tureson, PAC, Minnesota

Mehdi Dastrange, MD, MHA, Minnesota

Kent Svee, Minnesota

Ashley Viere, PA-C, Minnesota

Molly Yang, MD, Minnesota

Paige Sams, DO, Minnesota

Amit Reddy, MBBS, Mississippi

Jacqueline Brooke Banks, FNP-C, Mississippi

Lori Foxworth, CFNP, Mississippi

Nicki Lawson, FNP-C, Mississippi

Bikash Acharya, Missouri

Zafar Ahmad, PA-C, Missouri

Harleen Chela, MD, Missouri

Jeffrey Chung, MD, Missouri

Daniel Kornfeld, Missouri

Erika Leung, MD, MSc, Missouri

Lisa Moser, PA, Missouri

Mark Stiffler, Missouri

Tushar Tarun, MBBS, Missouri

Nicole McLaughlin, Missouri

Katy Lohmann, PA-C, Missouri

Jayasree Bodagala, MD, Missouri

Ravi Kiran Morumuru, ACMPE, Missouri

Matthew Brown, MD, FAAFP, Missouri

Ravikanth Tadi, Missouri

Bazgha Ahmad, DO, Missouri

Monica Hawkins, RN, Missouri

Karri Vesey, BSN, Montana

Madison Vertin, PA-C, Montana

Urmila Mukherjee, MD, Nebraska

Noah Wiedel, MD, Nebraska

Sidrah Sheikh, MD, MBBS, Nebraska

Mohammad Esmadi, MBBS, Nebraska

Jill Zabih, MD, Nebraska

Jody Frey-Burns, RN, Nevada

Adnan Akbar, MD, Nevada

Peter Gayed, MRCP, New Hampshire

Jonathan T. Huntington, MD, New Hampshire

Meghan Meehan, ACNP, New Hampshire

Saurabh Mehta, MD, New Jersey

Hanaa Benchekroun Belabbes, MD, MHA, New Jersey

Hwan Kim, MD, New Jersey

Mary Tobiasson, USA, New Jersey

Muhammad Khakwani, MD, New Jersey

Amita Maibam, MD, MPH, New Jersey

Kumar Rohit, MBBS, New Jersey

Crystal Benjamin, MD, New Jersey

Rafael Garabis, New Mexico

Sam MacBride, MD, New Mexico

Indra Peram, MD, New Mexico

Sarah Vertrees, DO, New Mexico

Aswani Kumar Alavala, MD, New Mexico

Christopher Anstine, New Mexico

Prathima Guruguri, MD, New Mexico

Diedre Hofinger, MD, FACP, New Mexico

Katharine Juarez, New Mexico

Amtul Mahavesh, MD, New Mexico

Francisco Marquez, New Mexico

Payal Sen, MD, New Mexico

Morgan Wong, DO, New Mexico

Kelly Berchou, New York

Ronald Cho, New York

Nishil Dalsania, New York

Carolyn Drake, MD, MPH, New York

Leanne Forman, New York

Valerie Gausman, New York

Laurie Jacobs, New York

Janice Jang, MD, New York

Sonia Kohli, MD, New York

Nancy Lee, PA, New York

Allen Lee, MD, New York

Matthew McCarthy, FACP, New York

Akram Mohammed, MD, New York

Jennifer Nead, New York

Kristal Persaud, PA, New York

Mariya Rozenblit, MD, New York

Christian Torres, MD, New York

Sasha De Jesus, MD, New York

Gabriella Polyak, New York

Nataliya Yuklyaeva, MD, New York

Riyaz Kamadoli, MD, New York

Ramanuj Chakravarty, New York

Adil Zaidi, MD, New York

Allison Walker, MD, New York

Himali Gandhi, New York

Alexey Yanilshtein, MD, New York

Ramsey Al-Khalil, New York

Latoya Codougan, MD, New York

Khan Najmi, MD, New York

Sara Stream, MD, New York

Bhuwan Poudyal, MD, New York

Khalil Anchouche, New York

Sarah Azarchi, New York

Susana Bejar, New York

Brian Chang, New York

Jonathan Chen, New York

Hailey Gupta, MD, New York

Medhavi Gupta, New York

Ali Khan, New York

Benjamin Kwok, MD, New York

Billy Lin, New York

Katherine Ni, New York

Jina Park, New York

Gabriel Perreault, New York

Luis Alberto Romero, New York

Payal Shah, New York

Punita Shroff, New York

Scott Statman, New York

Maria Sunseri, New York

Benjamin Verplanke, New York

Audrey Zhang, New York

Gaby Razzouk, MD, New York

Pranitha Mantrala, MD, New York

Marsha Antoine, New York

Kanica Yashi, New York

Navid Ahmed, New York

Tasha Richards, PA, New York

Connor Tryon, MD, New York

Naveen Yarlagadda, MD, New York

Alex Hogan, New York

Andrew Donohoe, CCM, MD, North Carolina

Brittany Forshay, MD, North Carolina

Kelly Hammerbeck, FNP, North Carolina

Jennifer Hausman, North Carolina

Babajide Obisesan, North Carolina

Kwadwo Ofori, MD, North Carolina

Eric Ofosu, MD, North Carolina

Kale Roth, North Carolina

Robert Soma, PA-C, North Carolina

Sommany Weber, North Carolina

Ronnie Jacobs, North Carolina

Muhammad Ghani, MD, MACP, MBBS, North Carolina

Madeline Treasure, North Carolina

Andrew McWilliams, MD, North Carolina

Karen Payne, ACNP, MPH, North Carolina

Rafal Poplawski, MD, North Carolina

James Seal, PA-C, North Carolina

Farheen Qureshi, DO, North Carolina

Basavatti Sowmya, MD, MBBS, North Carolina

Eshwar Lal, MD, North Carolina

Catherine Hathaway, MD, North Carolina

Sherif Naguib, FAAFP, North Carolina

Sara Skavroneck, North Carolina

Charles Ofosu, North Carolina

Alex Alburquerque, MD, Ohio

Isha Butler, DO, Ohio

Anne Carrol, MD, Ohio

Scott Childers, MD, Ohio

Philip Jonas, MD, Ohio

Ahmadreza Karimianpour, Ohio

Rahul Kumar, MD, Ohio

George Maidaa, MD, Ohio

Kevin McAninch, Ohio

Jill Mccourt, FNP, Ohio

Roxanne Oliver, Ohio

Farah Hussain, Ohio

Natasha Axton, PA-C, Ohio

Brooke Harris, ACNP, Ohio

Vidhya Murukesan, MD, Ohio

Sara Dong, Ohio

Christie Astor, FNP, Ohio

Sunita Mall, MD, Ohio

Sunita Mall, MD, Ohio

Fouzia Tariq, MD, Ohio

Kaveri Sivaruban, MD, Ohio

Eunice Quicho, Ohio

Smitha Achuthankutty, MD, Ohio

Harmanpreet Shinh, MD, Ohio

Maereg Tesfaye, Ohio

Kalyn Jolivette, MD, Ohio

Richelle Voth, PA-C, Oklahoma

Samuel J. Ratermann, MD, FAAFP, Oklahoma

Richelle Voth, PA-C, Oklahoma

Alden Forrester, MD, Oregon

Nicholas Brown, DO, Oregon

Ian Pennell-Walklin, MD, Oregon

Bruce Ramsey, Oregon

Kyle Brekke, DO, Oregon

Sarah Webber, MD, Oregon

Brian Beaudoin, MD, Pennsylvania

Glenn Bedell, MHSA, Pennsylvania

Cristina Green, AGACNP-DNP, Pennsylvania

Andrew Groff, Pennsylvania

Sulman Masood Hashmi, MBBS, Pennsylvania

Eric Kasprowicz, MD, MPH, Pennsylvania

Laura Leuenberger, Pennsylvania

James Liszewski, MD, Pennsylvania

Caitlyn Moss, Pennsylvania

Paul Seunghyun Nho, Pennsylvania

Rishan Patel, MD, Pennsylvania

Dilli R. Poudel, MBBS, Pennsylvania

Naveen Yellappa, MBBS, Pennsylvania

Usman Zulfiqar, Pennsylvania

Nina Jain, Pennsylvania

Bhumika Patel, DO, Pennsylvania

Jenna M. Diasio, PA-C, Pennsylvania

Malachi Courtney, MD, Pennsylvania

Sonia Arneja, MD, Pennsylvania

Ross Ellis, MD, Pennsylvania

Samreen Siddiqui, Pennsylvania

Jillian Zavodnick, Pennsylvania

Kinan Kassar, MD, Pennsylvania

Maritsa M. Scoulos-Hanson, Pennsylvania

Jennifer Taylor, PA-C, Pennsylvania

Steven Delaveris, DO, Pennsylvania

Danica Buzniak, DO, Rhode Island

Paul Browning, MD, South Carolina

Matt Coones, MD, South Carolina

Cedric Fisher, MD, South Carolina

Aloysius Jackson, MD, South Carolina

Katharine DuPont, MD, South Carolina

Michael Jenkins, MD, South Carolina

Jessica Hamilton, APRN, BC, FNP, South Carolina

Pamela Pyle, DO, South Carolina

Shakeel Ahmed, MBBS, MD, South Dakota

D. Bruce Eaton, MD, South Dakota

Drew Jorgensen, MD, South Dakota

Shelly Turbak, MSN, RN, South Dakota

Tamera Sturm, DO, South Dakota

Peggy Brooks, Tennessee

Joseph Garrido, MD, Tennessee

Lisa Grimes, FNP, Tennessee

Chennakesava Kummathi, MBBS, Tennessee

Victoria Okafor, Tennessee

Ashley Smith, Tennessee

Monisha Bhatia, Tennessee

Belinda Jenkins, APRN-BC, Tennessee

Kim Zahnke, MD, Tennessee

Robert Arias, Texas

Nicolas Batterton, MD, Texas

Scott DePaul, MD, Texas

Nancy Foster, Texas

Larry Hughes, Texas

Erin Koval, Texas

Femi Layiwola, MD, Texas

Krysta Lin, Texas

James J. Onorato, MD, PhD, Texas

Allison Stephenson, PA-C, Texas

Brandon Stormes, Texas

Rubin Simon, MD, Texas

Brian Anderson, DO, Texas

Hatim Chhatriwala, MD, Texas

Aziz Hammoud, Texas

Haru Yamamoto, MD, Texas

Lauren Schiegg, Texas

Victoria Grasso, DO, Texas

Victor Salcedo, MD, Texas

Rajiv Bhattarai, Texas

Iram Qureshi, DO, Texas

Lisa Hafemeister, FACHE, MHA, Texas

Helena Kurian, MD, Texas

Jessica Lin, Texas

Nathan Nowalk, MD, Texas

Keely Smith, MD, Texas

Jonathan Weiser, MD, Texas

Roland Prezas, DO, FAAFP, Texas

Allan Recto, AHIP, Texas

Regina Dimbo, Texas

Venkata Ghanta, Texas

Richmond Hunt, Texas

Vishal Patel, MD, Texas

Zain Sharif, MD, Texas

Rommel Del Rosario, MD, Texas

Khawer Khadimally, DO, Texas

Diogenes Valderrama, MD, Texas

Charles Ewoh, MD, Texas

Deepika Kilaru, Texas

Tilahun Belay, MD, Texas

Chandra S Reddy Navuluri, MD, Texas

Bradley Goad, DO, FACP, Virginia

Patrick Higdon, MD, Virginia

Gabriella Miller, MD, HMDC, Virginia

Miklos Szentirmai, MD, Virginia

Hyder Tamton, Virginia

Andra Mirescu, MD, Virginia

Olukayode Ojo, Virginia

Robert Szeles, MD, Virginia

Anya Cope, DO, Virginia

OsCiriah Press, MD, Virginia

Rikin Kadakia, MD, Virginia

Bryant Self, DO, Virginia

Sarah Sabo, ACNP, Virginia

Pedro A. Gonzales Alvarez, MD, Virginia

William Best, Virginia

Pushpanjali Basnyat, MD, Washington

Nikki Hartley-Jonason, Washington

Helen Johnsonwall, MD, Washington

Eric LaMotte, MD, Washington

Maher Muraywid, Washington

Evan Neal Paul, MD, Washington

Sarah Rogers, MD, Washington

Lindee Strizich, Washington

Maryam Tariq, MBBS, Washington

Meghaan Walsh, MD, Washington

Oleg Zbirun, MD, Washington

Meeta Sabnis, MD, Washington

James Kuo, MD, Washington

Liang Du, Washington

Syed Farhan Tabraiz Hashmi, MD, Washington

Jessica Jung, MD, Washington

Joshua Pelley, MD, Washington

Alex Yu, MD, Washington

Alfred Curnow, MD, Washington

Duhwan Kang, Washington

Gilbert Daniel, MD, Washington, D.C.

Eleanor Fitall, Washington, D.C.

Vinay Srinivasan, Washington, D.C.

Scott Wine, West Virginia

Trevor Miller, MBA, PA-C, West Virginia

Audrey Hiltunen, Wisconsin

Elina Litinskaya, Wisconsin

John M. Murphy, MD, Wisconsin

Tanya Pedretti, PA, Wisconsin

Adine Rodemeyer, MD, Wisconsin

Oghomwen Sule, MBBS, Wisconsin

Terrence Witt, MD, Wisconsin

Mayank Arora, Wisconsin

John D. MacDonald, MD, Wisconsin

Abigail Cook, Wisconsin

Mohamed Ibrahim, MD, Wisconsin

Aymen Khogali, MD, Wisconsin

Nicholas Haun, Wisconsin

Sandra Brown, Victoria, Australia

Alessandra Gessner, Alberta, Canada

Courtney Carlucci, British Columbia, Canada

Muhanad Y. Al Habash, Canada

Karen Tong, MD, Canada

Taku Yabuki, Japan

Liza van Loon, the Netherlands

Edward Gebuis, MD, the Netherlands

Abdisalan Afrah, MD, Qatar

Akhnuwkh Jones, Qatar

Mashuk Uddin, MBBS, MRCP, FRCP, Qatar

Ibrahim Yusuf Abubeker, MRCP, Qatar

Chih-Wei Tseng, Taiwan

Sawsan Abdel-Razig, MD, FACP, United Arab Emirates

The Society of Hospital Medicine welcomes its newest members:

Kwie-Hoa Siem, MD, Alaska

Frank Abene, Alabama

Kayla Maldonado, Alabama

Kenny Murray, MD, Alabama

Shanthan Ramidi, MD, Alabama

Lauren Hancock, APRN, Arkansas

William Hawkins, MD, Arkansas

Matthew Law, Arkansas

Emily Smith, MD, Arkansas

Firas Abbas, MBchB, Arizona

Shahid Ahmad, MD, MBBS, Arizona

Praveen Bheemanathini, Arizona

Atoosa Hosseini, Arizona

William McGrade, DO, Arizona

Konstantin Mazursky, DO, Arizona

Ibrahim Taweel, MD, Arizona

Kevin Virk, MD, FACP, Arizona

Kevin Virk, MD, FACP, Arizona

Mohemmedd Khalid Abbas, Arizona

Hasan Chaudhry, MD, Arizona

Kelly Kelleher, FAAP, Arizona

Priyanka Sultania Dudani, MBBS, Arizona

Krishna Kasireddy, MD, Arizona

Melanie Meguro, Arizona

Puneet Tuli, MD, Arizona

Jonathan Byrdy, DO, Arizona

Sarah Corral, DO, Arizona

Edward Maharam, MD, Arizona

Arvind Satyanarayan, DO, Arizona

Mayank Aggarwal, MD, Arizona

Syed Jafri, Arizona

Bujji Ainapurapu, MD, Arizona

Aaron Fernandes, MD, Arizona

Sonal Gandhi, Arizona

Sudhir Tutiki, Arizona

Navaneeth Kumar, MD, Arizona

Brian T. Courtney, MD, California

Won Jin Jeon, California

Veena Panduranga, MD, California

Jennifer Tinloy, DO, California

Debra Buckland Coffey, MCUSN, MD, California

Kathleen Teves, MD, California

Paul Goebel, MD, ACMPE, California

Shainy Hegde, California

Summaiya Muhammad, California

Desmond Wah, California

Chonn Khristin Ng, California

Almira Yang, DO, California

Salimah Boghani, MD, California

Stella Abhyankar, California

Cherie Ginwalla, MD, California

Armond Esmaili, California

Sarah Schaeffer, MD, MPH, California

Sophia Virani, MD, California

Dipti Munshi, MD, California

Judy Nguyen, DO, California

Daniel Owyang, DO, California

Christian Chiavetta, DO, California

David Reinert, DO, California

Joseph Pawlowski, MD, California

Eleanor Yang, California

Adrian Campo, MD, California

Emerson De Jesus, MD, California

Zachary Edmonds, MD, California

Trit Garg, California

Alexandra G. Ianculescu, MD, PhD, California

Felix Karp, MD, California

Cara Lai, California

Kristen Lew, MD, California

John Mogannam, California

Ameer Moussa, California

Neil Parikh, MD, MBA, California

Priya Reddy, California

Adam Simons, California

Sanjay Vadgama, MD, California

Kristofer Wills, DO, California

Michael Yang, MD, MS, California

Victor Ekuta, California,

Donna Colobong, PA-C, Colorado

Janna B. Dreason, FNP-C, Colorado

Cheryl English, NP-C, Colorado

Melanie Gerrior, MD, Colorado

Marciann Harris, NP, Colorado

Marsha Henke, MD, Colorado

Brett Hesse, Colorado

Naomi J Hipp, MD, Colorado

Aurell Horing, Colorado

Rachel Koch, DO, Colorado

Ed Marino, PA-C, Colorado

Marcus Reinhardt, MD, Colorado

Carol Runge, Colorado

Harshal Shah, Colorado

Leo Soehnlen, DO, Colorado

Anna Villalobos, MD, Colorado

Kathryn Whitfield, PA-C, Colorado

Jonathan Bei-Shing Young, MD, Colorado

Leah Damiani, MD, Colorado

Kathy Lynch, MD, Colorado

Micah Friedman, Colorado

Rachael Hilton, MD, Colorado

Madeline Koerner, Colorado

Chi Zheng, MD, Colorado

Chin-Kun Baw, MD, Connecticut

Alexandra Hawkins, NP, Connecticut

Vasundhara Singh, MD, MBBS, Connecticut

Ryan Quarles, MD, Connecticut

Debra Hernandez, APRN, BC, Connecticut

Karine Karapetyan, MD, Delaware

Choosak Burr, ARNP, Florida

Nelsi Mora, Florida

Mary Quillinan, Florida

Thuntanat Rachanakul, Florida

Samual W. Sauer, MD, MPH, Florida

Jennifer Tibangin, Florida

Keith Williams, MD, Florida

Eric Penedo, MD, Florida

Margaret Webb, Florida

Mark Bender, Florida

Brett Waress, MD, MHA, Florida

Giselle Racho, Florida

Bryan Thiel, Florida

Juan Loor Tuarez, MD, Florida

Christine Stopyra, Florida

Betsy Screws, ARNP, Florida

Jaimie Weber, MD, Florida

Priti Amin, MHA, Georgia

Naga Doddapaneni, Georgia

Stephanie Fletcher, Georgia

Disha Spath, MD, Georgia

Rafaela Wesley, DO, Georgia

Nikky Keer, DO, Georgia

James Kim, Georgia

Todd Martin, Georgia

Eli Mlaver, Georgia

Andrew Ritter, Georgia

Ali Al-Zubaidi, MBchB, Georgia

Deann Bing, MD, Georgia

Tushar Shah, Georgia

Cameron Straughn, DO, Georgia

Nobuhiro Ariyoshi, MEd, Hawaii

Prerna Kumar, Iowa

Jonathan Sebolt, MD, Iowa

Amy Tesar, DO, Iowa

Houng Chea, NP, Idaho

Finnegan Greer, PA-C, Idaho

Thao Nelson, PA, Idaho

Malatesha Gangappa, Idaho

Gloria Alumona, ACNP, Illinois

Ram Sanjeev Alur, Illinois

James Antoon, MD, FAAP, PhD, Illinois

Stefania Bailuc, MD, Illinois

Richard Huh, Illinois

Bhakti Patel, MD, Illinois

Frances Uy, ACNP, Illinois

Fernando Velazquez Vazquez, MD, Illinois

Tiffany White, MD, Illinois

Bryan P. Tully, MD, Illinois

Swati Gobhil, MBBS, Illinois

Lianghe Gao, Illinois

Gopi Astik, MD, Illinois

Marina Kovacevic, MD, Illinois

Abbie Raymond, DO, Illinois

Timothy Yung, Illinois

Ahmed Zahid, MD, Illinois

Cristina Corsini, MEd, Illinois

Faisal Rashid, MD, FACP, Illinois

Mansoor Ahmad, MD, Illinois

Matthew A. Strauch, DO, Illinois

Purshotham Reddy Grinne, Illinois

Nadia Nasreen, MD, Illinois

Maham Ashraf, MD, Indiana

Jennifer Gross, Indiana

Debasmita Mohapatra, MBBS, Indiana

Eric Scheper, Indiana

Katherine Gray, APRNBC, FNP, Indiana

Venkata Kureti, Indiana

Omer Al-Buoshkor, MD, Indiana

David Johnson, FNP, MSN, Indiana

Jonathan Salisbury, MD, Indiana

Debra Shapert, MSN, RN, Iowa

Lisa Carter, ARNP, Iowa

Matthew Woodham, Iowa

Tomoharu Suzuki, MD, Pharm, Japan

Khaldoun Haj, Kansas

Will Rogers, ACMPE, MA, MBA, Kansas

Karen Shumate, Kansas

Lisa Unruh, MD, Kansas

Matthew George, Kansas

Katie Washburn, DO, Kansas

Edwin Avallone, DO, Kentucky

Matthew Morris, Kentucky

Samantha Cappetto, MD, Kentucky

Jaison John, Kentucky

Ammar Al Jajeh, Kentucky

Joseph Bolger, MD, PhD, Louisiana

Clairissa Mulloy, Louisiana

Harish Talla, MD, Louisiana

John Amadon, Louisiana

Karthik Krishnareddy, Louisiana

Cheryl DeGrandpre, PA-C, Maine

Katherine Liu, MD, Maine

Sarah Sedney, MD, Maine

Aksana Afanasenka, MD, Maryland

Syed Nazeer Mahmood, MBBS, Maryland

Joseph Apata, MD, Maryland

Russom Ghebrai, MD, Maryland

Musa Momoh, MD, Maryland

Antanina Voit, Maryland

Dejene Kassaye, MD, MSC, Maryland

Shams Quazi, MD, FACP, MS, Maryland

Dawn Roelofs, FNP, MSN, Maryland

Kirsten Austad, MD, Massachusetts

Yoel Carrasquillo Vega, MD, Massachusetts

Michele Gaudet, NP, Massachusetts

Karina Mejias, Massachusetts

Peter Rohloff, MD, PhD, Massachusetts

Jennifer Schaeffer, Massachusetts

James Shaw, MD, Massachusetts

Renee Wheeler, Massachusetts

Angela Freeman, PA, PA-C, Massachusetts

Supriya Parvatini, MD, Massachusetts

Karen Jiang, MD, Massachusetts

Roula E. Abou-Nader, MD, Massachusetts

Shreekant Vasudhev, MD, Massachusetts

Nivedita Adabala, MD, MBBS, Michigan

Robert Behrendt, RN, BSN, Michigan

Molly Belisle, Michigan

Christine Dugan, MD, Michigan

Baljinder Gill, Michigan

Kellie Herringa, PA-C, Michigan

Christine Klingert, Michigan

Kathy Mitchell, Michigan

Aimee Vos, Michigan

Alyssa Churchill, DO, Michigan

Mailvaganam Sridharan, MD, Michigan

Atul Kapoor, MD, MBBS, Michigan

Anitha Kompally, MD, MBBS, Michigan

Nicole Webb, PA-C, Michigan

Abdulqadir Ahmad, MD, Minnesota

John Patrick Eikens, Minnesota

Bobbi Jo Jensen, PA-C, Minnesota

Rachel Keuseman, Minnesota

Stephen Palmquist, Minnesota

Manit Singla, MD, Minnesota

Douglas Berg, Minnesota

Nathan Palmolea, Minnesota

Molly Tureson, PAC, Minnesota

Mehdi Dastrange, MD, MHA, Minnesota

Kent Svee, Minnesota

Ashley Viere, PA-C, Minnesota

Molly Yang, MD, Minnesota

Paige Sams, DO, Minnesota

Amit Reddy, MBBS, Mississippi

Jacqueline Brooke Banks, FNP-C, Mississippi

Lori Foxworth, CFNP, Mississippi

Nicki Lawson, FNP-C, Mississippi

Bikash Acharya, Missouri

Zafar Ahmad, PA-C, Missouri

Harleen Chela, MD, Missouri

Jeffrey Chung, MD, Missouri

Daniel Kornfeld, Missouri

Erika Leung, MD, MSc, Missouri

Lisa Moser, PA, Missouri

Mark Stiffler, Missouri

Tushar Tarun, MBBS, Missouri

Nicole McLaughlin, Missouri

Katy Lohmann, PA-C, Missouri

Jayasree Bodagala, MD, Missouri

Ravi Kiran Morumuru, ACMPE, Missouri

Matthew Brown, MD, FAAFP, Missouri

Ravikanth Tadi, Missouri

Bazgha Ahmad, DO, Missouri

Monica Hawkins, RN, Missouri

Karri Vesey, BSN, Montana

Madison Vertin, PA-C, Montana

Urmila Mukherjee, MD, Nebraska

Noah Wiedel, MD, Nebraska

Sidrah Sheikh, MD, MBBS, Nebraska

Mohammad Esmadi, MBBS, Nebraska

Jill Zabih, MD, Nebraska

Jody Frey-Burns, RN, Nevada

Adnan Akbar, MD, Nevada

Peter Gayed, MRCP, New Hampshire

Jonathan T. Huntington, MD, New Hampshire

Meghan Meehan, ACNP, New Hampshire

Saurabh Mehta, MD, New Jersey

Hanaa Benchekroun Belabbes, MD, MHA, New Jersey

Hwan Kim, MD, New Jersey

Mary Tobiasson, USA, New Jersey

Muhammad Khakwani, MD, New Jersey

Amita Maibam, MD, MPH, New Jersey

Kumar Rohit, MBBS, New Jersey

Crystal Benjamin, MD, New Jersey

Rafael Garabis, New Mexico

Sam MacBride, MD, New Mexico

Indra Peram, MD, New Mexico

Sarah Vertrees, DO, New Mexico

Aswani Kumar Alavala, MD, New Mexico

Christopher Anstine, New Mexico

Prathima Guruguri, MD, New Mexico

Diedre Hofinger, MD, FACP, New Mexico

Katharine Juarez, New Mexico

Amtul Mahavesh, MD, New Mexico

Francisco Marquez, New Mexico

Payal Sen, MD, New Mexico

Morgan Wong, DO, New Mexico

Kelly Berchou, New York

Ronald Cho, New York

Nishil Dalsania, New York

Carolyn Drake, MD, MPH, New York

Leanne Forman, New York

Valerie Gausman, New York

Laurie Jacobs, New York

Janice Jang, MD, New York

Sonia Kohli, MD, New York

Nancy Lee, PA, New York

Allen Lee, MD, New York

Matthew McCarthy, FACP, New York

Akram Mohammed, MD, New York

Jennifer Nead, New York

Kristal Persaud, PA, New York

Mariya Rozenblit, MD, New York

Christian Torres, MD, New York

Sasha De Jesus, MD, New York

Gabriella Polyak, New York

Nataliya Yuklyaeva, MD, New York

Riyaz Kamadoli, MD, New York

Ramanuj Chakravarty, New York

Adil Zaidi, MD, New York

Allison Walker, MD, New York

Himali Gandhi, New York

Alexey Yanilshtein, MD, New York

Ramsey Al-Khalil, New York

Latoya Codougan, MD, New York

Khan Najmi, MD, New York

Sara Stream, MD, New York

Bhuwan Poudyal, MD, New York

Khalil Anchouche, New York

Sarah Azarchi, New York

Susana Bejar, New York

Brian Chang, New York

Jonathan Chen, New York

Hailey Gupta, MD, New York

Medhavi Gupta, New York

Ali Khan, New York

Benjamin Kwok, MD, New York

Billy Lin, New York

Katherine Ni, New York

Jina Park, New York

Gabriel Perreault, New York

Luis Alberto Romero, New York

Payal Shah, New York

Punita Shroff, New York

Scott Statman, New York

Maria Sunseri, New York

Benjamin Verplanke, New York

Audrey Zhang, New York

Gaby Razzouk, MD, New York

Pranitha Mantrala, MD, New York

Marsha Antoine, New York

Kanica Yashi, New York

Navid Ahmed, New York

Tasha Richards, PA, New York

Connor Tryon, MD, New York

Naveen Yarlagadda, MD, New York

Alex Hogan, New York

Andrew Donohoe, CCM, MD, North Carolina

Brittany Forshay, MD, North Carolina

Kelly Hammerbeck, FNP, North Carolina

Jennifer Hausman, North Carolina

Babajide Obisesan, North Carolina

Kwadwo Ofori, MD, North Carolina

Eric Ofosu, MD, North Carolina

Kale Roth, North Carolina

Robert Soma, PA-C, North Carolina

Sommany Weber, North Carolina

Ronnie Jacobs, North Carolina

Muhammad Ghani, MD, MACP, MBBS, North Carolina

Madeline Treasure, North Carolina

Andrew McWilliams, MD, North Carolina

Karen Payne, ACNP, MPH, North Carolina

Rafal Poplawski, MD, North Carolina

James Seal, PA-C, North Carolina

Farheen Qureshi, DO, North Carolina

Basavatti Sowmya, MD, MBBS, North Carolina

Eshwar Lal, MD, North Carolina

Catherine Hathaway, MD, North Carolina

Sherif Naguib, FAAFP, North Carolina

Sara Skavroneck, North Carolina

Charles Ofosu, North Carolina

Alex Alburquerque, MD, Ohio

Isha Butler, DO, Ohio

Anne Carrol, MD, Ohio

Scott Childers, MD, Ohio

Philip Jonas, MD, Ohio

Ahmadreza Karimianpour, Ohio

Rahul Kumar, MD, Ohio

George Maidaa, MD, Ohio

Kevin McAninch, Ohio

Jill Mccourt, FNP, Ohio

Roxanne Oliver, Ohio

Farah Hussain, Ohio

Natasha Axton, PA-C, Ohio

Brooke Harris, ACNP, Ohio

Vidhya Murukesan, MD, Ohio

Sara Dong, Ohio

Christie Astor, FNP, Ohio

Sunita Mall, MD, Ohio

Sunita Mall, MD, Ohio

Fouzia Tariq, MD, Ohio

Kaveri Sivaruban, MD, Ohio

Eunice Quicho, Ohio

Smitha Achuthankutty, MD, Ohio

Harmanpreet Shinh, MD, Ohio

Maereg Tesfaye, Ohio

Kalyn Jolivette, MD, Ohio

Richelle Voth, PA-C, Oklahoma

Samuel J. Ratermann, MD, FAAFP, Oklahoma

Richelle Voth, PA-C, Oklahoma

Alden Forrester, MD, Oregon

Nicholas Brown, DO, Oregon

Ian Pennell-Walklin, MD, Oregon

Bruce Ramsey, Oregon

Kyle Brekke, DO, Oregon

Sarah Webber, MD, Oregon

Brian Beaudoin, MD, Pennsylvania

Glenn Bedell, MHSA, Pennsylvania

Cristina Green, AGACNP-DNP, Pennsylvania

Andrew Groff, Pennsylvania

Sulman Masood Hashmi, MBBS, Pennsylvania

Eric Kasprowicz, MD, MPH, Pennsylvania

Laura Leuenberger, Pennsylvania

James Liszewski, MD, Pennsylvania

Caitlyn Moss, Pennsylvania

Paul Seunghyun Nho, Pennsylvania

Rishan Patel, MD, Pennsylvania

Dilli R. Poudel, MBBS, Pennsylvania

Naveen Yellappa, MBBS, Pennsylvania

Usman Zulfiqar, Pennsylvania

Nina Jain, Pennsylvania

Bhumika Patel, DO, Pennsylvania

Jenna M. Diasio, PA-C, Pennsylvania

Malachi Courtney, MD, Pennsylvania

Sonia Arneja, MD, Pennsylvania

Ross Ellis, MD, Pennsylvania

Samreen Siddiqui, Pennsylvania

Jillian Zavodnick, Pennsylvania

Kinan Kassar, MD, Pennsylvania

Maritsa M. Scoulos-Hanson, Pennsylvania

Jennifer Taylor, PA-C, Pennsylvania

Steven Delaveris, DO, Pennsylvania

Danica Buzniak, DO, Rhode Island

Paul Browning, MD, South Carolina

Matt Coones, MD, South Carolina

Cedric Fisher, MD, South Carolina

Aloysius Jackson, MD, South Carolina

Katharine DuPont, MD, South Carolina

Michael Jenkins, MD, South Carolina

Jessica Hamilton, APRN, BC, FNP, South Carolina

Pamela Pyle, DO, South Carolina

Shakeel Ahmed, MBBS, MD, South Dakota

D. Bruce Eaton, MD, South Dakota

Drew Jorgensen, MD, South Dakota

Shelly Turbak, MSN, RN, South Dakota

Tamera Sturm, DO, South Dakota

Peggy Brooks, Tennessee

Joseph Garrido, MD, Tennessee

Lisa Grimes, FNP, Tennessee

Chennakesava Kummathi, MBBS, Tennessee

Victoria Okafor, Tennessee

Ashley Smith, Tennessee

Monisha Bhatia, Tennessee

Belinda Jenkins, APRN-BC, Tennessee

Kim Zahnke, MD, Tennessee

Robert Arias, Texas

Nicolas Batterton, MD, Texas

Scott DePaul, MD, Texas

Nancy Foster, Texas

Larry Hughes, Texas

Erin Koval, Texas

Femi Layiwola, MD, Texas

Krysta Lin, Texas

James J. Onorato, MD, PhD, Texas

Allison Stephenson, PA-C, Texas

Brandon Stormes, Texas

Rubin Simon, MD, Texas

Brian Anderson, DO, Texas

Hatim Chhatriwala, MD, Texas

Aziz Hammoud, Texas

Haru Yamamoto, MD, Texas

Lauren Schiegg, Texas

Victoria Grasso, DO, Texas

Victor Salcedo, MD, Texas

Rajiv Bhattarai, Texas

Iram Qureshi, DO, Texas

Lisa Hafemeister, FACHE, MHA, Texas

Helena Kurian, MD, Texas

Jessica Lin, Texas

Nathan Nowalk, MD, Texas

Keely Smith, MD, Texas

Jonathan Weiser, MD, Texas

Roland Prezas, DO, FAAFP, Texas

Allan Recto, AHIP, Texas

Regina Dimbo, Texas

Venkata Ghanta, Texas

Richmond Hunt, Texas

Vishal Patel, MD, Texas

Zain Sharif, MD, Texas

Rommel Del Rosario, MD, Texas

Khawer Khadimally, DO, Texas

Diogenes Valderrama, MD, Texas

Charles Ewoh, MD, Texas

Deepika Kilaru, Texas

Tilahun Belay, MD, Texas

Chandra S Reddy Navuluri, MD, Texas

Bradley Goad, DO, FACP, Virginia

Patrick Higdon, MD, Virginia

Gabriella Miller, MD, HMDC, Virginia

Miklos Szentirmai, MD, Virginia

Hyder Tamton, Virginia

Andra Mirescu, MD, Virginia

Olukayode Ojo, Virginia

Robert Szeles, MD, Virginia

Anya Cope, DO, Virginia

OsCiriah Press, MD, Virginia

Rikin Kadakia, MD, Virginia

Bryant Self, DO, Virginia

Sarah Sabo, ACNP, Virginia

Pedro A. Gonzales Alvarez, MD, Virginia

William Best, Virginia

Pushpanjali Basnyat, MD, Washington

Nikki Hartley-Jonason, Washington

Helen Johnsonwall, MD, Washington

Eric LaMotte, MD, Washington

Maher Muraywid, Washington

Evan Neal Paul, MD, Washington

Sarah Rogers, MD, Washington

Lindee Strizich, Washington

Maryam Tariq, MBBS, Washington

Meghaan Walsh, MD, Washington

Oleg Zbirun, MD, Washington

Meeta Sabnis, MD, Washington

James Kuo, MD, Washington

Liang Du, Washington

Syed Farhan Tabraiz Hashmi, MD, Washington

Jessica Jung, MD, Washington

Joshua Pelley, MD, Washington

Alex Yu, MD, Washington

Alfred Curnow, MD, Washington

Duhwan Kang, Washington

Gilbert Daniel, MD, Washington, D.C.

Eleanor Fitall, Washington, D.C.

Vinay Srinivasan, Washington, D.C.

Scott Wine, West Virginia

Trevor Miller, MBA, PA-C, West Virginia

Audrey Hiltunen, Wisconsin

Elina Litinskaya, Wisconsin

John M. Murphy, MD, Wisconsin

Tanya Pedretti, PA, Wisconsin

Adine Rodemeyer, MD, Wisconsin

Oghomwen Sule, MBBS, Wisconsin

Terrence Witt, MD, Wisconsin

Mayank Arora, Wisconsin

John D. MacDonald, MD, Wisconsin

Abigail Cook, Wisconsin

Mohamed Ibrahim, MD, Wisconsin

Aymen Khogali, MD, Wisconsin

Nicholas Haun, Wisconsin

Sandra Brown, Victoria, Australia

Alessandra Gessner, Alberta, Canada

Courtney Carlucci, British Columbia, Canada

Muhanad Y. Al Habash, Canada

Karen Tong, MD, Canada

Taku Yabuki, Japan

Liza van Loon, the Netherlands

Edward Gebuis, MD, the Netherlands

Abdisalan Afrah, MD, Qatar

Akhnuwkh Jones, Qatar

Mashuk Uddin, MBBS, MRCP, FRCP, Qatar

Ibrahim Yusuf Abubeker, MRCP, Qatar

Chih-Wei Tseng, Taiwan

Sawsan Abdel-Razig, MD, FACP, United Arab Emirates

Clozapine and long-acting injectable antipsychotic medications were most effective at preventing rehospitalization and treatment failure among patients with schizophrenia, according to a large prospective cohort study reported online June 7.

“The risk of rehospitalization is about 20% to 30% lower during long-acting injectable treatments, compared with equivalent oral formulations,” wrote Jari Tiihonen, MD, PhD, of the department of clinical neuroscience at the Karolinska Institutet in Stockholm, together with his associates.

Selection bias is a major problem in clinical trials of antipsychotics because up to 90% of patients are excluded for suicidal or antisocial behavior, substance abuse, refusal to participate, or comorbidities, the researchers noted. Observational studies also suffer from selection bias because of residual confounding. To address this issue, the researchers analyzed linked databases of 29,823 adults in Sweden with schizophrenia by using within-individual Cox proportional hazards regression analysis, in which each patient serves as his or her own control. Patients were diagnosed by 2006 and followed through 2013 (JAMA Psychiatry. 2017 June 7. doi: 10.1001/jamapsychiatry.2017.1322). A total of 13,042 patients (44%) were rehospitalized during follow-up. Rehospitalization was significantly less likely when patients were receiving oral clozapine or long-acting injectable antipsychotics, including paliperidone, zuclopenthixol, perphenazine, and olanzapine, than when they were not on antipsychotics. Hazard ratios for these comparisons were statistically significant, ranging from 0.51 to 0.58, the researchers reported.

In the overall cohort, patients were about 22% less likely to be rehospitalized when they received long-acting injectable antipsychotics instead of equivalent oral formulations (HR, 0.78; 95% confidence interval, 0.72-0.84; P less than .001). For newly diagnosed patients, this protective effect reached 32% (HR, 0.68; 95% CI, 0.53-0.86). The overall rate of treatment failure was 72%, but this outcome was significantly less likely when patients received clozapine (HR, 0.58; 95% CI, 0.53-0.63) or any of the long-acting injectable antipsychotics (HR, 0.65-0.80) instead of the most widely used medication, oral olanzapine. Those trends held up during several sensitivity analyses, the researchers noted.

The major reason long-acting injectables led to better outcomes probably is tied to adherence, “and the rationale for developing long-acting injectable formulations was to improve adherence,” Dr. Tilhonen and his associates wrote.

Dr. Tiihonen and his associates cited several limitations. For example, their results comparing the effectiveness of antipsychotics “can be generalized only to white populations and high-income countries in which all antipsychotic treatments are reimbursed by the state,” they wrote.

Nevertheless, they concluded that their results suggest that substantial differences exist “between specific antipsychotic agents and between routes of administration concerning the risk of rehospitalization and treatment failure among patients with schizophrenia.”

Janssen-Cilag funded the study. Dr. Tiihonen disclosed ties to Janssen-Cilag and several other pharmaceutical companies.

Clozapine and long-acting injectable antipsychotic medications were most effective at preventing rehospitalization and treatment failure among patients with schizophrenia, according to a large prospective cohort study reported online June 7.

“The risk of rehospitalization is about 20% to 30% lower during long-acting injectable treatments, compared with equivalent oral formulations,” wrote Jari Tiihonen, MD, PhD, of the department of clinical neuroscience at the Karolinska Institutet in Stockholm, together with his associates.

Selection bias is a major problem in clinical trials of antipsychotics because up to 90% of patients are excluded for suicidal or antisocial behavior, substance abuse, refusal to participate, or comorbidities, the researchers noted. Observational studies also suffer from selection bias because of residual confounding. To address this issue, the researchers analyzed linked databases of 29,823 adults in Sweden with schizophrenia by using within-individual Cox proportional hazards regression analysis, in which each patient serves as his or her own control. Patients were diagnosed by 2006 and followed through 2013 (JAMA Psychiatry. 2017 June 7. doi: 10.1001/jamapsychiatry.2017.1322). A total of 13,042 patients (44%) were rehospitalized during follow-up. Rehospitalization was significantly less likely when patients were receiving oral clozapine or long-acting injectable antipsychotics, including paliperidone, zuclopenthixol, perphenazine, and olanzapine, than when they were not on antipsychotics. Hazard ratios for these comparisons were statistically significant, ranging from 0.51 to 0.58, the researchers reported.

In the overall cohort, patients were about 22% less likely to be rehospitalized when they received long-acting injectable antipsychotics instead of equivalent oral formulations (HR, 0.78; 95% confidence interval, 0.72-0.84; P less than .001). For newly diagnosed patients, this protective effect reached 32% (HR, 0.68; 95% CI, 0.53-0.86). The overall rate of treatment failure was 72%, but this outcome was significantly less likely when patients received clozapine (HR, 0.58; 95% CI, 0.53-0.63) or any of the long-acting injectable antipsychotics (HR, 0.65-0.80) instead of the most widely used medication, oral olanzapine. Those trends held up during several sensitivity analyses, the researchers noted.

The major reason long-acting injectables led to better outcomes probably is tied to adherence, “and the rationale for developing long-acting injectable formulations was to improve adherence,” Dr. Tilhonen and his associates wrote.

Dr. Tiihonen and his associates cited several limitations. For example, their results comparing the effectiveness of antipsychotics “can be generalized only to white populations and high-income countries in which all antipsychotic treatments are reimbursed by the state,” they wrote.

Nevertheless, they concluded that their results suggest that substantial differences exist “between specific antipsychotic agents and between routes of administration concerning the risk of rehospitalization and treatment failure among patients with schizophrenia.”

Janssen-Cilag funded the study. Dr. Tiihonen disclosed ties to Janssen-Cilag and several other pharmaceutical companies.

Clozapine and long-acting injectable antipsychotic medications were most effective at preventing rehospitalization and treatment failure among patients with schizophrenia, according to a large prospective cohort study reported online June 7.

“The risk of rehospitalization is about 20% to 30% lower during long-acting injectable treatments, compared with equivalent oral formulations,” wrote Jari Tiihonen, MD, PhD, of the department of clinical neuroscience at the Karolinska Institutet in Stockholm, together with his associates.

Selection bias is a major problem in clinical trials of antipsychotics because up to 90% of patients are excluded for suicidal or antisocial behavior, substance abuse, refusal to participate, or comorbidities, the researchers noted. Observational studies also suffer from selection bias because of residual confounding. To address this issue, the researchers analyzed linked databases of 29,823 adults in Sweden with schizophrenia by using within-individual Cox proportional hazards regression analysis, in which each patient serves as his or her own control. Patients were diagnosed by 2006 and followed through 2013 (JAMA Psychiatry. 2017 June 7. doi: 10.1001/jamapsychiatry.2017.1322). A total of 13,042 patients (44%) were rehospitalized during follow-up. Rehospitalization was significantly less likely when patients were receiving oral clozapine or long-acting injectable antipsychotics, including paliperidone, zuclopenthixol, perphenazine, and olanzapine, than when they were not on antipsychotics. Hazard ratios for these comparisons were statistically significant, ranging from 0.51 to 0.58, the researchers reported.

In the overall cohort, patients were about 22% less likely to be rehospitalized when they received long-acting injectable antipsychotics instead of equivalent oral formulations (HR, 0.78; 95% confidence interval, 0.72-0.84; P less than .001). For newly diagnosed patients, this protective effect reached 32% (HR, 0.68; 95% CI, 0.53-0.86). The overall rate of treatment failure was 72%, but this outcome was significantly less likely when patients received clozapine (HR, 0.58; 95% CI, 0.53-0.63) or any of the long-acting injectable antipsychotics (HR, 0.65-0.80) instead of the most widely used medication, oral olanzapine. Those trends held up during several sensitivity analyses, the researchers noted.

The major reason long-acting injectables led to better outcomes probably is tied to adherence, “and the rationale for developing long-acting injectable formulations was to improve adherence,” Dr. Tilhonen and his associates wrote.

Dr. Tiihonen and his associates cited several limitations. For example, their results comparing the effectiveness of antipsychotics “can be generalized only to white populations and high-income countries in which all antipsychotic treatments are reimbursed by the state,” they wrote.

Nevertheless, they concluded that their results suggest that substantial differences exist “between specific antipsychotic agents and between routes of administration concerning the risk of rehospitalization and treatment failure among patients with schizophrenia.”

Janssen-Cilag funded the study. Dr. Tiihonen disclosed ties to Janssen-Cilag and several other pharmaceutical companies.

BOSTON – Late chronotype may have a deleterious impact on glucose homeostasis independent of obesity in preadolescents aged 10-13 years, according to a small study.

Late chronotype – or an individual’s preference for later sleep and food intake – is associated with higher body mass index (BMI), risk incidence of type 2 diabetes mellitus, hemoglobin A1c, and risk of hypertension in adults. It is also associated with higher BMI, lower dietary restraint, and lower HDL cholesterol in adolescents. This study was the first to focus on chronotype and glycemic control in children on the cusp of or in early puberty.

In participants tested during the summer months, the actigraphy-derived mid-sleep time on free days – an objective measure of chronotype – was associated positively with fasting plasma glucose (P = 0.048). “This is an important point because it highlights the objective measure of chronotype, whereas questionnaires can be more subjective,” said Magdalena Dumin, MD, at the annual meeting of Associated Professional Sleep Societies.

Debra L. Beck/Frontline Medical News

BOSTON – Late chronotype may have a deleterious impact on glucose homeostasis independent of obesity in preadolescents aged 10-13 years, according to a small study.

Late chronotype – or an individual’s preference for later sleep and food intake – is associated with higher body mass index (BMI), risk incidence of type 2 diabetes mellitus, hemoglobin A1c, and risk of hypertension in adults. It is also associated with higher BMI, lower dietary restraint, and lower HDL cholesterol in adolescents. This study was the first to focus on chronotype and glycemic control in children on the cusp of or in early puberty.

In participants tested during the summer months, the actigraphy-derived mid-sleep time on free days – an objective measure of chronotype – was associated positively with fasting plasma glucose (P = 0.048). “This is an important point because it highlights the objective measure of chronotype, whereas questionnaires can be more subjective,” said Magdalena Dumin, MD, at the annual meeting of Associated Professional Sleep Societies.

Debra L. Beck/Frontline Medical News

BOSTON – Late chronotype may have a deleterious impact on glucose homeostasis independent of obesity in preadolescents aged 10-13 years, according to a small study.

Late chronotype – or an individual’s preference for later sleep and food intake – is associated with higher body mass index (BMI), risk incidence of type 2 diabetes mellitus, hemoglobin A1c, and risk of hypertension in adults. It is also associated with higher BMI, lower dietary restraint, and lower HDL cholesterol in adolescents. This study was the first to focus on chronotype and glycemic control in children on the cusp of or in early puberty.

In participants tested during the summer months, the actigraphy-derived mid-sleep time on free days – an objective measure of chronotype – was associated positively with fasting plasma glucose (P = 0.048). “This is an important point because it highlights the objective measure of chronotype, whereas questionnaires can be more subjective,” said Magdalena Dumin, MD, at the annual meeting of Associated Professional Sleep Societies.

Debra L. Beck/Frontline Medical News

CHICAGO – When it comes to oxaliplatin-based therapy for stage III colon cancer patients with low recurrence risk, 3 is preferable to 6 months and may also be preferable in those with higher recurrence risk – particularly if they are receiving oxaliplatin with capecitabine (CAPOX), according to findings from a prospective pooled analysis of data from six phase III trials.

The findings have immediate practice-changing implications, according to Axel Grothey, MD, of the Mayo Clinic Cancer Center, Rochester, Minn.

The preplanned analysis of the concurrently conducted trials (the International Duration Evaluation of Adjuvant chemotherapy [IDEA] collaboration), which included 12,834 patients receiving either oxaliplatin with fluorouracil and folinic acid (FOLFOX) or CAPOX, showed that, at a median follow-up of 39 months, the overall 3-year disease-free survival (DFS) rates differed by only 0.9% between those receiving 3 vs. 6 months of therapy (DFS, 74.6% and 75.5%, respectively). The difference between the groups was not statistically significant (estimated disease-free hazard ratio, 1.07), Dr. Grothey reported during a press briefing at the annual meeting of the American Society of Clinical Oncology.

However, grade 2 or greater neurotoxicity was greatly reduced, occurring in 17% vs. 48% of FOLFOX patients treated for 3 vs. 6 months, respectively, and in 15% vs. 45% of CAPOX patients treated for 3 vs. 6 months, respectively.

When outcomes were analyzed based on risk of recurrence, low-risk patients (those with T1-3 N1 disease) had 3-year disease-free survival rates of 83.1% and 83.3% with 3 vs. 6 months of therapy, and high-risk patients (T4 or N2 disease) had 3-year disease-free survival of 62.7% vs. 64.4% with 3 vs. 6 months of therapy.

When outcomes were analyzed by regimen, the FOLFOX patients (about 60% of the patient population) had 3-year DFS of 73.6% and 76.0% with 3 vs. 6 months of therapy, and the CAPOX patients had 3-year DFS of 75.9% and 74.8%, respectively.

In this video interview, Dr. Grothey discusses the findings, as well as the importance of federal funding for cancer research, which is underscored by the findings.

He also discusses the IDEA Collaboration consensus based on the results, which calls for 3 months of therapy in low-risk patients and for an individualized approach based on tolerability of therapy, patient preference, assessment of recurrence risk, and treatment regimen (CAPOX vs. FOLFOX) in higher-risk patients.

“We now have very important, very solid data to engage patients in discussion [about] how to individualize the duration of therapy,” he said.

Dr. Grothey reported having no relevant disclosures.

[email protected]

CHICAGO – When it comes to oxaliplatin-based therapy for stage III colon cancer patients with low recurrence risk, 3 is preferable to 6 months and may also be preferable in those with higher recurrence risk – particularly if they are receiving oxaliplatin with capecitabine (CAPOX), according to findings from a prospective pooled analysis of data from six phase III trials.

The findings have immediate practice-changing implications, according to Axel Grothey, MD, of the Mayo Clinic Cancer Center, Rochester, Minn.

The preplanned analysis of the concurrently conducted trials (the International Duration Evaluation of Adjuvant chemotherapy [IDEA] collaboration), which included 12,834 patients receiving either oxaliplatin with fluorouracil and folinic acid (FOLFOX) or CAPOX, showed that, at a median follow-up of 39 months, the overall 3-year disease-free survival (DFS) rates differed by only 0.9% between those receiving 3 vs. 6 months of therapy (DFS, 74.6% and 75.5%, respectively). The difference between the groups was not statistically significant (estimated disease-free hazard ratio, 1.07), Dr. Grothey reported during a press briefing at the annual meeting of the American Society of Clinical Oncology.

However, grade 2 or greater neurotoxicity was greatly reduced, occurring in 17% vs. 48% of FOLFOX patients treated for 3 vs. 6 months, respectively, and in 15% vs. 45% of CAPOX patients treated for 3 vs. 6 months, respectively.

When outcomes were analyzed based on risk of recurrence, low-risk patients (those with T1-3 N1 disease) had 3-year disease-free survival rates of 83.1% and 83.3% with 3 vs. 6 months of therapy, and high-risk patients (T4 or N2 disease) had 3-year disease-free survival of 62.7% vs. 64.4% with 3 vs. 6 months of therapy.

When outcomes were analyzed by regimen, the FOLFOX patients (about 60% of the patient population) had 3-year DFS of 73.6% and 76.0% with 3 vs. 6 months of therapy, and the CAPOX patients had 3-year DFS of 75.9% and 74.8%, respectively.

In this video interview, Dr. Grothey discusses the findings, as well as the importance of federal funding for cancer research, which is underscored by the findings.

He also discusses the IDEA Collaboration consensus based on the results, which calls for 3 months of therapy in low-risk patients and for an individualized approach based on tolerability of therapy, patient preference, assessment of recurrence risk, and treatment regimen (CAPOX vs. FOLFOX) in higher-risk patients.

“We now have very important, very solid data to engage patients in discussion [about] how to individualize the duration of therapy,” he said.

Dr. Grothey reported having no relevant disclosures.

[email protected]

CHICAGO – When it comes to oxaliplatin-based therapy for stage III colon cancer patients with low recurrence risk, 3 is preferable to 6 months and may also be preferable in those with higher recurrence risk – particularly if they are receiving oxaliplatin with capecitabine (CAPOX), according to findings from a prospective pooled analysis of data from six phase III trials.

The findings have immediate practice-changing implications, according to Axel Grothey, MD, of the Mayo Clinic Cancer Center, Rochester, Minn.

The preplanned analysis of the concurrently conducted trials (the International Duration Evaluation of Adjuvant chemotherapy [IDEA] collaboration), which included 12,834 patients receiving either oxaliplatin with fluorouracil and folinic acid (FOLFOX) or CAPOX, showed that, at a median follow-up of 39 months, the overall 3-year disease-free survival (DFS) rates differed by only 0.9% between those receiving 3 vs. 6 months of therapy (DFS, 74.6% and 75.5%, respectively). The difference between the groups was not statistically significant (estimated disease-free hazard ratio, 1.07), Dr. Grothey reported during a press briefing at the annual meeting of the American Society of Clinical Oncology.

However, grade 2 or greater neurotoxicity was greatly reduced, occurring in 17% vs. 48% of FOLFOX patients treated for 3 vs. 6 months, respectively, and in 15% vs. 45% of CAPOX patients treated for 3 vs. 6 months, respectively.

When outcomes were analyzed based on risk of recurrence, low-risk patients (those with T1-3 N1 disease) had 3-year disease-free survival rates of 83.1% and 83.3% with 3 vs. 6 months of therapy, and high-risk patients (T4 or N2 disease) had 3-year disease-free survival of 62.7% vs. 64.4% with 3 vs. 6 months of therapy.

When outcomes were analyzed by regimen, the FOLFOX patients (about 60% of the patient population) had 3-year DFS of 73.6% and 76.0% with 3 vs. 6 months of therapy, and the CAPOX patients had 3-year DFS of 75.9% and 74.8%, respectively.

In this video interview, Dr. Grothey discusses the findings, as well as the importance of federal funding for cancer research, which is underscored by the findings.

He also discusses the IDEA Collaboration consensus based on the results, which calls for 3 months of therapy in low-risk patients and for an individualized approach based on tolerability of therapy, patient preference, assessment of recurrence risk, and treatment regimen (CAPOX vs. FOLFOX) in higher-risk patients.

“We now have very important, very solid data to engage patients in discussion [about] how to individualize the duration of therapy,” he said.

Dr. Grothey reported having no relevant disclosures.

[email protected]

CHICAGO – Adding the anti-HER2 monoclonal antibody pertuzumab to adjuvant chemotherapy and trastuzumab significantly improved invasive disease-free survival in the randomized, placebo-controlled Adjuvant Pertuzumab and Herceptin in Initial Therapy (APHINITY) study of patients with HER2-positive early breast cancer.

At a median follow-up of 45.4 months, invasive disease-free survival (IDFS) events occurred in 171 of 2,400 patients (7.1%) who received pertuzumab, compared with 210 of 2,405 patients (8.7%) who received placebo (hazard ratio, 0.81). This 19% reduction in risk of an IDFS event was statistically significant, Gunter von Minckwitz, MD, PhD, reported at the annual meeting of the American Society of Clinical Oncology.

The estimated IDFS rate at 3 years was 94.1% in the pertuzumab arm, and 93.2% in the placebo arm, said Dr. von Minckwitz of the German Breast Group, Neu-Isenburg.

Study subjects were patients with adequately excised HER2-positive, pT1-3 early breast cancer. Patients were randomized to receive adjuvant chemotherapy plus 1 year of either trastuzumab plus pertuzumab, or trastuzumab plus placebo.

In a video interview, Dr. von Minckwitz discusses the study results, including outcomes in node-positive vs. node-negative patients, early overall survival findings, and safety.

“We are using pertuzumab right now in many countries for the neoadjuvant setting,” he said, explaining that existing approvals were granted conditionally in the absence of evidence regarding long-term benefits. “With the APHINITY study ... use of pertuzumab either in the neoadjuvant setting or in the higher-risk adjuvant setting is something that is supported now with evidence.”

[email protected]

CHICAGO – Adding the anti-HER2 monoclonal antibody pertuzumab to adjuvant chemotherapy and trastuzumab significantly improved invasive disease-free survival in the randomized, placebo-controlled Adjuvant Pertuzumab and Herceptin in Initial Therapy (APHINITY) study of patients with HER2-positive early breast cancer.

At a median follow-up of 45.4 months, invasive disease-free survival (IDFS) events occurred in 171 of 2,400 patients (7.1%) who received pertuzumab, compared with 210 of 2,405 patients (8.7%) who received placebo (hazard ratio, 0.81). This 19% reduction in risk of an IDFS event was statistically significant, Gunter von Minckwitz, MD, PhD, reported at the annual meeting of the American Society of Clinical Oncology.

The estimated IDFS rate at 3 years was 94.1% in the pertuzumab arm, and 93.2% in the placebo arm, said Dr. von Minckwitz of the German Breast Group, Neu-Isenburg.

Study subjects were patients with adequately excised HER2-positive, pT1-3 early breast cancer. Patients were randomized to receive adjuvant chemotherapy plus 1 year of either trastuzumab plus pertuzumab, or trastuzumab plus placebo.

In a video interview, Dr. von Minckwitz discusses the study results, including outcomes in node-positive vs. node-negative patients, early overall survival findings, and safety.

“We are using pertuzumab right now in many countries for the neoadjuvant setting,” he said, explaining that existing approvals were granted conditionally in the absence of evidence regarding long-term benefits. “With the APHINITY study ... use of pertuzumab either in the neoadjuvant setting or in the higher-risk adjuvant setting is something that is supported now with evidence.”

[email protected]

CHICAGO – Adding the anti-HER2 monoclonal antibody pertuzumab to adjuvant chemotherapy and trastuzumab significantly improved invasive disease-free survival in the randomized, placebo-controlled Adjuvant Pertuzumab and Herceptin in Initial Therapy (APHINITY) study of patients with HER2-positive early breast cancer.

At a median follow-up of 45.4 months, invasive disease-free survival (IDFS) events occurred in 171 of 2,400 patients (7.1%) who received pertuzumab, compared with 210 of 2,405 patients (8.7%) who received placebo (hazard ratio, 0.81). This 19% reduction in risk of an IDFS event was statistically significant, Gunter von Minckwitz, MD, PhD, reported at the annual meeting of the American Society of Clinical Oncology.

The estimated IDFS rate at 3 years was 94.1% in the pertuzumab arm, and 93.2% in the placebo arm, said Dr. von Minckwitz of the German Breast Group, Neu-Isenburg.

Study subjects were patients with adequately excised HER2-positive, pT1-3 early breast cancer. Patients were randomized to receive adjuvant chemotherapy plus 1 year of either trastuzumab plus pertuzumab, or trastuzumab plus placebo.

In a video interview, Dr. von Minckwitz discusses the study results, including outcomes in node-positive vs. node-negative patients, early overall survival findings, and safety.

“We are using pertuzumab right now in many countries for the neoadjuvant setting,” he said, explaining that existing approvals were granted conditionally in the absence of evidence regarding long-term benefits. “With the APHINITY study ... use of pertuzumab either in the neoadjuvant setting or in the higher-risk adjuvant setting is something that is supported now with evidence.”

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Certain species of vaginal bacteria rapidly metabolized topical tenofovir, which was three times less effective at preventing HIV in women with predominantly these vaginal microbiota, according to results of a study published in Science.

Key culprits were Gardnerella vaginalis and other anaerobic species associated with bacterial vaginosis, reported Nichole R. Klatt, PhD, of the University of Washington, Seattle, and her associates. The findings could help explain the lower and widely variable efficacy rates of topical microbicides in clinical HIV prevention trials, they added.

Cynthia Goldsmith, CDC

Certain species of vaginal bacteria rapidly metabolized topical tenofovir, which was three times less effective at preventing HIV in women with predominantly these vaginal microbiota, according to results of a study published in Science.

Key culprits were Gardnerella vaginalis and other anaerobic species associated with bacterial vaginosis, reported Nichole R. Klatt, PhD, of the University of Washington, Seattle, and her associates. The findings could help explain the lower and widely variable efficacy rates of topical microbicides in clinical HIV prevention trials, they added.

Cynthia Goldsmith, CDC

Certain species of vaginal bacteria rapidly metabolized topical tenofovir, which was three times less effective at preventing HIV in women with predominantly these vaginal microbiota, according to results of a study published in Science.

Key culprits were Gardnerella vaginalis and other anaerobic species associated with bacterial vaginosis, reported Nichole R. Klatt, PhD, of the University of Washington, Seattle, and her associates. The findings could help explain the lower and widely variable efficacy rates of topical microbicides in clinical HIV prevention trials, they added.

Cynthia Goldsmith, CDC

When HIV-discordant couples wish to conceive, several strategies can effectively prevent men from infecting their female partners, according to an analysis in Morbidity and Mortality Weekly Report.

Using sperm from an HIV-negative donor remains the safest choice, but current methods of sperm washing make in vitro fertilization (IVF) or intrauterine insemination (IUI) a low-risk alternative, especially when used together with highly active antiretroviral therapy (HAART) and preexposure prophylaxis (PrEP), wrote Jennifer F. Kawwass, MD, and her associates in the division of reproductive health at the Centers for Disease Control and Prevention, Atlanta (MMWR Morb Mortal Wkly Rep. 2017;66:554-7).

Previously, the CDC recommended against insemination with semen from HIV-infected men. The new report reverses that position, citing epidemiologic and laboratory evidence that conception can occur safely when HIV-discordant couples use combined strategies including HAART, PrEP, and either condomless intercourse limited to the time around ovulation, or sperm washing prior to IVF or IUI.

When HIV-discordant couples wish to conceive, several strategies can effectively prevent men from infecting their female partners, according to an analysis in Morbidity and Mortality Weekly Report.

Using sperm from an HIV-negative donor remains the safest choice, but current methods of sperm washing make in vitro fertilization (IVF) or intrauterine insemination (IUI) a low-risk alternative, especially when used together with highly active antiretroviral therapy (HAART) and preexposure prophylaxis (PrEP), wrote Jennifer F. Kawwass, MD, and her associates in the division of reproductive health at the Centers for Disease Control and Prevention, Atlanta (MMWR Morb Mortal Wkly Rep. 2017;66:554-7).

Previously, the CDC recommended against insemination with semen from HIV-infected men. The new report reverses that position, citing epidemiologic and laboratory evidence that conception can occur safely when HIV-discordant couples use combined strategies including HAART, PrEP, and either condomless intercourse limited to the time around ovulation, or sperm washing prior to IVF or IUI.

When HIV-discordant couples wish to conceive, several strategies can effectively prevent men from infecting their female partners, according to an analysis in Morbidity and Mortality Weekly Report.

Using sperm from an HIV-negative donor remains the safest choice, but current methods of sperm washing make in vitro fertilization (IVF) or intrauterine insemination (IUI) a low-risk alternative, especially when used together with highly active antiretroviral therapy (HAART) and preexposure prophylaxis (PrEP), wrote Jennifer F. Kawwass, MD, and her associates in the division of reproductive health at the Centers for Disease Control and Prevention, Atlanta (MMWR Morb Mortal Wkly Rep. 2017;66:554-7).

Previously, the CDC recommended against insemination with semen from HIV-infected men. The new report reverses that position, citing epidemiologic and laboratory evidence that conception can occur safely when HIV-discordant couples use combined strategies including HAART, PrEP, and either condomless intercourse limited to the time around ovulation, or sperm washing prior to IVF or IUI.

VANCOUVER – The Endometriosis Fertility Index accurately predicts a woman’s chances to conceive naturally with endometriosis, according to findings from a prospective cohort study.

“We’re quite confident that this is a very good system to give women a reasonable idea of their chances of conceiving naturally versus a recommendation to have IVF,” Aaron Budden, Bmed, Mmed, of the Royal Hospital for Women in Sydney, said at the World Congress on Endometriosis.

The Endometriosis Fertility Index (EFI) was first published in 2010 (Fertil Steril. 2010 Oct;94[5]:1609-15). In the recent study, researchers found that live birth rates after 3 years closely matched the rates calculated by the tool. “This is one of the most useful systems I’ve ever seen, because it takes into account historical events, as well as the time of endometriosis surgery,” Dr. Budden said.

The researchers enrolled 141 consecutive women who had undergone fertility-saving laparoscopic excision of stage III or stage IV endometriosis and attempted to conceive naturally. During follow-up, the researchers contacted the patients to determine live births, and calculated the EFI score based on a woman’s age, duration of infertility, previous pregnancy, American Society for Reproductive Medicine endometriosis classification, and their least adnexal function score. “The least function score is based off the functional capacity of the fallopian tube, fimbriae, and ovary, where the score is calculated by which of these is least functional on both right and left side,” Dr. Budden said.

The researchers included women with stage III and stage IV endometriosis because this group is often referred for in vitro fertilization (IVF). “But we found that in women with an advanced stage of endometriosis, those with EFI scores of 9 and 10 still had quite a significant chance of conceiving at 3 years, compared to women who had EFI scores of 0 to 2,” Dr. Budden said.

More than a third of the women (35%) had stage III endometriosis, and 65% had stage IV. The mean follow-up period was 56 months. Overall, 46% achieved live births.

In women with an EFI score of 9-10, the success rate was 67% at 3 years. Nearly half (48%) of women with scores of 7-8 were successful at 3 years, as were 38% with scores of 5-6, and 17% with scores of 3-4. Among women with scores of 0-2, there were no live births at 3 years.

About 58% of the women in the study had undergone previous laparoscopic surgery. The researchers found that live births were associated with complete resection of disease (hazard ratio, 2.33; P = .036) and no previous laparoscopy (HR, 2.36; P less than .001).

“One of the things we have to say is that your best chance at conceiving is if you excise all the endometriosis and you do it the first time, rather than needing a second surgery,” Dr. Budden said.

The tool can also be used to help identify patients most likely to benefit from assisted reproduction. Women with EFI scores of 0-2 had a 0% chance of conceiving naturally when followed out to 5 years, but a 39% chance with IVF. “That’s a group that you would thoroughly recommend going to IVF rather than trying to conceive naturally,” Dr. Budden said in an interview.

The study was funded by a variety of non-industry sources. Dr. Budden reported having no financial disclosures.

VANCOUVER – The Endometriosis Fertility Index accurately predicts a woman’s chances to conceive naturally with endometriosis, according to findings from a prospective cohort study.

“We’re quite confident that this is a very good system to give women a reasonable idea of their chances of conceiving naturally versus a recommendation to have IVF,” Aaron Budden, Bmed, Mmed, of the Royal Hospital for Women in Sydney, said at the World Congress on Endometriosis.

The Endometriosis Fertility Index (EFI) was first published in 2010 (Fertil Steril. 2010 Oct;94[5]:1609-15). In the recent study, researchers found that live birth rates after 3 years closely matched the rates calculated by the tool. “This is one of the most useful systems I’ve ever seen, because it takes into account historical events, as well as the time of endometriosis surgery,” Dr. Budden said.

The researchers enrolled 141 consecutive women who had undergone fertility-saving laparoscopic excision of stage III or stage IV endometriosis and attempted to conceive naturally. During follow-up, the researchers contacted the patients to determine live births, and calculated the EFI score based on a woman’s age, duration of infertility, previous pregnancy, American Society for Reproductive Medicine endometriosis classification, and their least adnexal function score. “The least function score is based off the functional capacity of the fallopian tube, fimbriae, and ovary, where the score is calculated by which of these is least functional on both right and left side,” Dr. Budden said.

The researchers included women with stage III and stage IV endometriosis because this group is often referred for in vitro fertilization (IVF). “But we found that in women with an advanced stage of endometriosis, those with EFI scores of 9 and 10 still had quite a significant chance of conceiving at 3 years, compared to women who had EFI scores of 0 to 2,” Dr. Budden said.

More than a third of the women (35%) had stage III endometriosis, and 65% had stage IV. The mean follow-up period was 56 months. Overall, 46% achieved live births.

In women with an EFI score of 9-10, the success rate was 67% at 3 years. Nearly half (48%) of women with scores of 7-8 were successful at 3 years, as were 38% with scores of 5-6, and 17% with scores of 3-4. Among women with scores of 0-2, there were no live births at 3 years.

About 58% of the women in the study had undergone previous laparoscopic surgery. The researchers found that live births were associated with complete resection of disease (hazard ratio, 2.33; P = .036) and no previous laparoscopy (HR, 2.36; P less than .001).

“One of the things we have to say is that your best chance at conceiving is if you excise all the endometriosis and you do it the first time, rather than needing a second surgery,” Dr. Budden said.

The tool can also be used to help identify patients most likely to benefit from assisted reproduction. Women with EFI scores of 0-2 had a 0% chance of conceiving naturally when followed out to 5 years, but a 39% chance with IVF. “That’s a group that you would thoroughly recommend going to IVF rather than trying to conceive naturally,” Dr. Budden said in an interview.

The study was funded by a variety of non-industry sources. Dr. Budden reported having no financial disclosures.

VANCOUVER – The Endometriosis Fertility Index accurately predicts a woman’s chances to conceive naturally with endometriosis, according to findings from a prospective cohort study.

“We’re quite confident that this is a very good system to give women a reasonable idea of their chances of conceiving naturally versus a recommendation to have IVF,” Aaron Budden, Bmed, Mmed, of the Royal Hospital for Women in Sydney, said at the World Congress on Endometriosis.

The Endometriosis Fertility Index (EFI) was first published in 2010 (Fertil Steril. 2010 Oct;94[5]:1609-15). In the recent study, researchers found that live birth rates after 3 years closely matched the rates calculated by the tool. “This is one of the most useful systems I’ve ever seen, because it takes into account historical events, as well as the time of endometriosis surgery,” Dr. Budden said.

The researchers enrolled 141 consecutive women who had undergone fertility-saving laparoscopic excision of stage III or stage IV endometriosis and attempted to conceive naturally. During follow-up, the researchers contacted the patients to determine live births, and calculated the EFI score based on a woman’s age, duration of infertility, previous pregnancy, American Society for Reproductive Medicine endometriosis classification, and their least adnexal function score. “The least function score is based off the functional capacity of the fallopian tube, fimbriae, and ovary, where the score is calculated by which of these is least functional on both right and left side,” Dr. Budden said.

The researchers included women with stage III and stage IV endometriosis because this group is often referred for in vitro fertilization (IVF). “But we found that in women with an advanced stage of endometriosis, those with EFI scores of 9 and 10 still had quite a significant chance of conceiving at 3 years, compared to women who had EFI scores of 0 to 2,” Dr. Budden said.

More than a third of the women (35%) had stage III endometriosis, and 65% had stage IV. The mean follow-up period was 56 months. Overall, 46% achieved live births.

In women with an EFI score of 9-10, the success rate was 67% at 3 years. Nearly half (48%) of women with scores of 7-8 were successful at 3 years, as were 38% with scores of 5-6, and 17% with scores of 3-4. Among women with scores of 0-2, there were no live births at 3 years.

About 58% of the women in the study had undergone previous laparoscopic surgery. The researchers found that live births were associated with complete resection of disease (hazard ratio, 2.33; P = .036) and no previous laparoscopy (HR, 2.36; P less than .001).

“One of the things we have to say is that your best chance at conceiving is if you excise all the endometriosis and you do it the first time, rather than needing a second surgery,” Dr. Budden said.

The tool can also be used to help identify patients most likely to benefit from assisted reproduction. Women with EFI scores of 0-2 had a 0% chance of conceiving naturally when followed out to 5 years, but a 39% chance with IVF. “That’s a group that you would thoroughly recommend going to IVF rather than trying to conceive naturally,” Dr. Budden said in an interview.

The study was funded by a variety of non-industry sources. Dr. Budden reported having no financial disclosures.

WASHINGTON – The addition of noninvasive ventilation to home oxygen therapy regimens correlated with increased time to readmission or death among patients with exacerbated chronic obstructive pulmonary diseases (COPD), according to a study presented at an international conference of the American Thoracic Society.

Among 116 patients observed with COPD, the 57 patients given home oxygen and noninvasive ventilation reported an average time to readmission of 4.3 months, compared with 1.4 months among the 59 patients given only home oxygen, according to Patrick B. Murphy, PhD, of St. Thomas’ Hospital, London (JAMA. 2017 May 21. doi: 10.1001/jama.2017.4451), who presented this research on the same day it was published in JAMA.

[email protected]

On Twitter @eaztweets

WASHINGTON – The addition of noninvasive ventilation to home oxygen therapy regimens correlated with increased time to readmission or death among patients with exacerbated chronic obstructive pulmonary diseases (COPD), according to a study presented at an international conference of the American Thoracic Society.

Among 116 patients observed with COPD, the 57 patients given home oxygen and noninvasive ventilation reported an average time to readmission of 4.3 months, compared with 1.4 months among the 59 patients given only home oxygen, according to Patrick B. Murphy, PhD, of St. Thomas’ Hospital, London (JAMA. 2017 May 21. doi: 10.1001/jama.2017.4451), who presented this research on the same day it was published in JAMA.

[email protected]

On Twitter @eaztweets

WASHINGTON – The addition of noninvasive ventilation to home oxygen therapy regimens correlated with increased time to readmission or death among patients with exacerbated chronic obstructive pulmonary diseases (COPD), according to a study presented at an international conference of the American Thoracic Society.

Among 116 patients observed with COPD, the 57 patients given home oxygen and noninvasive ventilation reported an average time to readmission of 4.3 months, compared with 1.4 months among the 59 patients given only home oxygen, according to Patrick B. Murphy, PhD, of St. Thomas’ Hospital, London (JAMA. 2017 May 21. doi: 10.1001/jama.2017.4451), who presented this research on the same day it was published in JAMA.

[email protected]

On Twitter @eaztweets

CHICAGO – In what’s being hailed as practice-changing findings, the anaplastic lymphoma kinase inhibitor alectinib (Alecensa) was associated with more than doubled progression-free survival (PFS), compared with crizotinib (Xalkori), the current standard of care, in patients with treatment-naive non–small cell lung cancer (NSCLC) positive for ALK.

Additionally, in the global, phase III trial, alectinib was associated with a significantly lower risk of progression to CNS metastases, a common complication of advanced ALK+ NSCLC, reported Alice T. Shaw, MD, PhD, of the Massachusetts General Hospital Cancer Center in Boston, on behalf of investigators in the ALEX trial.

Neil Osterweil/Frontline Medical news

CHICAGO – In what’s being hailed as practice-changing findings, the anaplastic lymphoma kinase inhibitor alectinib (Alecensa) was associated with more than doubled progression-free survival (PFS), compared with crizotinib (Xalkori), the current standard of care, in patients with treatment-naive non–small cell lung cancer (NSCLC) positive for ALK.

Additionally, in the global, phase III trial, alectinib was associated with a significantly lower risk of progression to CNS metastases, a common complication of advanced ALK+ NSCLC, reported Alice T. Shaw, MD, PhD, of the Massachusetts General Hospital Cancer Center in Boston, on behalf of investigators in the ALEX trial.

Neil Osterweil/Frontline Medical news

CHICAGO – In what’s being hailed as practice-changing findings, the anaplastic lymphoma kinase inhibitor alectinib (Alecensa) was associated with more than doubled progression-free survival (PFS), compared with crizotinib (Xalkori), the current standard of care, in patients with treatment-naive non–small cell lung cancer (NSCLC) positive for ALK.

Additionally, in the global, phase III trial, alectinib was associated with a significantly lower risk of progression to CNS metastases, a common complication of advanced ALK+ NSCLC, reported Alice T. Shaw, MD, PhD, of the Massachusetts General Hospital Cancer Center in Boston, on behalf of investigators in the ALEX trial.

Neil Osterweil/Frontline Medical news