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1.10 Common Clinical Diagnoses and Conditions: Constipation
Introduction
Constipation is a common pediatric problem, accounting for 3% of all outpatient visits and up to 0.5% of all pediatric hospital admissions. While constipation affects many children, only a very small minority have an organic cause for their symptoms. The great majority have functional constipation, also termed idiopathic constipation or functional fecal retention. Pediatric hospitalists frequently care for children admitted for fecal impaction or encounter constipation as a comorbidity during other admissions. Therefore, pediatric hospitalists must be knowledgeable about the differential diagnosis of organic and functional causes of constipation. In addition, they must be adept at the implementation of evidence-based approaches for relieving stool burden and providing education for patients and caregivers.
Knowledge
Pediatric hospitalists should be able to:
- Discuss the self-perpetuating nature of constipation, the physiologic changes related to colonic volume and defecation signaling, and the pathophysiology of encopresis and soiling.
- Discuss the elements of the history which are pertinent; including family history, stooling history, age at which first stool was passed, current stooling pattern, diet history, prior test results, previous treatments and response, and related behaviors such as withholding, stooling avoidance, and others.
- Describe the elements of the physical exam that would help confirm or contradict the diagnosis of constipation.
- Describe common factors that might lead to functional or non-organic constipation, including cognitive disabilities, toilet/school bathroom phobia, poor toilet training experiences, sexual abuse, low fiber diet, dehydration, underfeeding, and inattentiveness to internal stooling signals.
- Compare and contrast key historical and physical exam findings for uncommon but important medical causes of constipation (such as hypothyroidism, hypercalcemia, hypokalemia, cystic fibrosis, diabetes, cerebral palsy, Hirschsprung disease, and others), including the key features that would distinguish them from a diagnosis of functional constipation.
- Discuss the pathophysiology of the development of constipation in the post-operative setting, including preventative strategies and medical management.
- Identify common medications that can lead to constipation, including opioids, antacids, anticholinergics, antidepressants, and sympathomimetics.
- Describe common inpatient medical conditions that can lead to secondary constipation, such as inactivity or immobility, poor oral intake, sedation, ileus from other gastrointestinal disorders, and others.
- Discuss the inpatient treatment options for acute stool impaction and symptomatic constipation, as well as options for outpatient management strategies (such as therapies available, side effects, timing of periodic monitoring, duration of therapy, and others).
- Describe the admission criteria for fecal impaction and circumstances that should trigger consultation with a gastroenterologist or pediatric surgeon.
Skills
Pediatric hospitalists should be able to:
- Diagnose and differentiate functional and organic constipation by performing a careful history and exam.
- Identify signs and symptoms of developing stool retention as a secondary problem during hospitalization and effectively respond with an appropriate treatment plan.
- Select appropriate diagnostic studies to evaluate functional or organic causes of constipation when suspected and correctly interpret results.
- Prescribe and manage disimpaction and/or whole bowel clean out regimens, accounting for potential complications of therapy (such as fluid and electrolyte shifts and others), designation of an appropriate endpoint, and discharge criteria.
- Engage consultants (such as registered dieticians, gastroenterology, psychology, and others) efficiently when indicated.
- Create a discharge maintenance therapy regimen and follow-up plan, including education of the patient and the family/caregivers.
Attitudes
Pediatric hospitalists should be able to:
- Realize responsibility and long-term importance of promoting communication with patients and caregivers about the causes of constipation and the goals and duration of therapy.
- Reflect on the psychological implications inherent in the diagnosis of constipation including the impact of parental frustration, toileting expectations, frequent soiling, and the non-volitional nature of the disorder.
- Acknowledge and provide support for patients and caregivers on common pitfalls in the treatment of chronic constipation.
Systems Organization and Improvement
In order to improve efficiency and quality within their organizations, pediatric hospitalists should:
- Lead, coordinate, or participate in the development and implementation of evidence-based and cost-effective clinical guidelines to improve the quality of care for inpatient management of constipation and whole bowel clean out.
- Collaborate with subspecialty consultants, including surgeons and gastroenterologists, to improve the care and management of complex patients with constipation.
- Coordinate the care of professional staff (including primary care providers and subspecialists) to ensure communication about, enhance adherence to, and provide education to patients and the family/caregivers regarding ongoing treatment regimens.
1. Evaluation and treatment of functional constipation in infants and children: Evidence-based recommendations from ESPGHAN-NASPGHAN. J Pediatr Gastro Nutr. 2014;58(2):258-274. https://doi.org/10.1097/MPG.0000000000000266.
Introduction
Constipation is a common pediatric problem, accounting for 3% of all outpatient visits and up to 0.5% of all pediatric hospital admissions. While constipation affects many children, only a very small minority have an organic cause for their symptoms. The great majority have functional constipation, also termed idiopathic constipation or functional fecal retention. Pediatric hospitalists frequently care for children admitted for fecal impaction or encounter constipation as a comorbidity during other admissions. Therefore, pediatric hospitalists must be knowledgeable about the differential diagnosis of organic and functional causes of constipation. In addition, they must be adept at the implementation of evidence-based approaches for relieving stool burden and providing education for patients and caregivers.
Knowledge
Pediatric hospitalists should be able to:
- Discuss the self-perpetuating nature of constipation, the physiologic changes related to colonic volume and defecation signaling, and the pathophysiology of encopresis and soiling.
- Discuss the elements of the history which are pertinent; including family history, stooling history, age at which first stool was passed, current stooling pattern, diet history, prior test results, previous treatments and response, and related behaviors such as withholding, stooling avoidance, and others.
- Describe the elements of the physical exam that would help confirm or contradict the diagnosis of constipation.
- Describe common factors that might lead to functional or non-organic constipation, including cognitive disabilities, toilet/school bathroom phobia, poor toilet training experiences, sexual abuse, low fiber diet, dehydration, underfeeding, and inattentiveness to internal stooling signals.
- Compare and contrast key historical and physical exam findings for uncommon but important medical causes of constipation (such as hypothyroidism, hypercalcemia, hypokalemia, cystic fibrosis, diabetes, cerebral palsy, Hirschsprung disease, and others), including the key features that would distinguish them from a diagnosis of functional constipation.
- Discuss the pathophysiology of the development of constipation in the post-operative setting, including preventative strategies and medical management.
- Identify common medications that can lead to constipation, including opioids, antacids, anticholinergics, antidepressants, and sympathomimetics.
- Describe common inpatient medical conditions that can lead to secondary constipation, such as inactivity or immobility, poor oral intake, sedation, ileus from other gastrointestinal disorders, and others.
- Discuss the inpatient treatment options for acute stool impaction and symptomatic constipation, as well as options for outpatient management strategies (such as therapies available, side effects, timing of periodic monitoring, duration of therapy, and others).
- Describe the admission criteria for fecal impaction and circumstances that should trigger consultation with a gastroenterologist or pediatric surgeon.
Skills
Pediatric hospitalists should be able to:
- Diagnose and differentiate functional and organic constipation by performing a careful history and exam.
- Identify signs and symptoms of developing stool retention as a secondary problem during hospitalization and effectively respond with an appropriate treatment plan.
- Select appropriate diagnostic studies to evaluate functional or organic causes of constipation when suspected and correctly interpret results.
- Prescribe and manage disimpaction and/or whole bowel clean out regimens, accounting for potential complications of therapy (such as fluid and electrolyte shifts and others), designation of an appropriate endpoint, and discharge criteria.
- Engage consultants (such as registered dieticians, gastroenterology, psychology, and others) efficiently when indicated.
- Create a discharge maintenance therapy regimen and follow-up plan, including education of the patient and the family/caregivers.
Attitudes
Pediatric hospitalists should be able to:
- Realize responsibility and long-term importance of promoting communication with patients and caregivers about the causes of constipation and the goals and duration of therapy.
- Reflect on the psychological implications inherent in the diagnosis of constipation including the impact of parental frustration, toileting expectations, frequent soiling, and the non-volitional nature of the disorder.
- Acknowledge and provide support for patients and caregivers on common pitfalls in the treatment of chronic constipation.
Systems Organization and Improvement
In order to improve efficiency and quality within their organizations, pediatric hospitalists should:
- Lead, coordinate, or participate in the development and implementation of evidence-based and cost-effective clinical guidelines to improve the quality of care for inpatient management of constipation and whole bowel clean out.
- Collaborate with subspecialty consultants, including surgeons and gastroenterologists, to improve the care and management of complex patients with constipation.
- Coordinate the care of professional staff (including primary care providers and subspecialists) to ensure communication about, enhance adherence to, and provide education to patients and the family/caregivers regarding ongoing treatment regimens.
Introduction
Constipation is a common pediatric problem, accounting for 3% of all outpatient visits and up to 0.5% of all pediatric hospital admissions. While constipation affects many children, only a very small minority have an organic cause for their symptoms. The great majority have functional constipation, also termed idiopathic constipation or functional fecal retention. Pediatric hospitalists frequently care for children admitted for fecal impaction or encounter constipation as a comorbidity during other admissions. Therefore, pediatric hospitalists must be knowledgeable about the differential diagnosis of organic and functional causes of constipation. In addition, they must be adept at the implementation of evidence-based approaches for relieving stool burden and providing education for patients and caregivers.
Knowledge
Pediatric hospitalists should be able to:
- Discuss the self-perpetuating nature of constipation, the physiologic changes related to colonic volume and defecation signaling, and the pathophysiology of encopresis and soiling.
- Discuss the elements of the history which are pertinent; including family history, stooling history, age at which first stool was passed, current stooling pattern, diet history, prior test results, previous treatments and response, and related behaviors such as withholding, stooling avoidance, and others.
- Describe the elements of the physical exam that would help confirm or contradict the diagnosis of constipation.
- Describe common factors that might lead to functional or non-organic constipation, including cognitive disabilities, toilet/school bathroom phobia, poor toilet training experiences, sexual abuse, low fiber diet, dehydration, underfeeding, and inattentiveness to internal stooling signals.
- Compare and contrast key historical and physical exam findings for uncommon but important medical causes of constipation (such as hypothyroidism, hypercalcemia, hypokalemia, cystic fibrosis, diabetes, cerebral palsy, Hirschsprung disease, and others), including the key features that would distinguish them from a diagnosis of functional constipation.
- Discuss the pathophysiology of the development of constipation in the post-operative setting, including preventative strategies and medical management.
- Identify common medications that can lead to constipation, including opioids, antacids, anticholinergics, antidepressants, and sympathomimetics.
- Describe common inpatient medical conditions that can lead to secondary constipation, such as inactivity or immobility, poor oral intake, sedation, ileus from other gastrointestinal disorders, and others.
- Discuss the inpatient treatment options for acute stool impaction and symptomatic constipation, as well as options for outpatient management strategies (such as therapies available, side effects, timing of periodic monitoring, duration of therapy, and others).
- Describe the admission criteria for fecal impaction and circumstances that should trigger consultation with a gastroenterologist or pediatric surgeon.
Skills
Pediatric hospitalists should be able to:
- Diagnose and differentiate functional and organic constipation by performing a careful history and exam.
- Identify signs and symptoms of developing stool retention as a secondary problem during hospitalization and effectively respond with an appropriate treatment plan.
- Select appropriate diagnostic studies to evaluate functional or organic causes of constipation when suspected and correctly interpret results.
- Prescribe and manage disimpaction and/or whole bowel clean out regimens, accounting for potential complications of therapy (such as fluid and electrolyte shifts and others), designation of an appropriate endpoint, and discharge criteria.
- Engage consultants (such as registered dieticians, gastroenterology, psychology, and others) efficiently when indicated.
- Create a discharge maintenance therapy regimen and follow-up plan, including education of the patient and the family/caregivers.
Attitudes
Pediatric hospitalists should be able to:
- Realize responsibility and long-term importance of promoting communication with patients and caregivers about the causes of constipation and the goals and duration of therapy.
- Reflect on the psychological implications inherent in the diagnosis of constipation including the impact of parental frustration, toileting expectations, frequent soiling, and the non-volitional nature of the disorder.
- Acknowledge and provide support for patients and caregivers on common pitfalls in the treatment of chronic constipation.
Systems Organization and Improvement
In order to improve efficiency and quality within their organizations, pediatric hospitalists should:
- Lead, coordinate, or participate in the development and implementation of evidence-based and cost-effective clinical guidelines to improve the quality of care for inpatient management of constipation and whole bowel clean out.
- Collaborate with subspecialty consultants, including surgeons and gastroenterologists, to improve the care and management of complex patients with constipation.
- Coordinate the care of professional staff (including primary care providers and subspecialists) to ensure communication about, enhance adherence to, and provide education to patients and the family/caregivers regarding ongoing treatment regimens.
1. Evaluation and treatment of functional constipation in infants and children: Evidence-based recommendations from ESPGHAN-NASPGHAN. J Pediatr Gastro Nutr. 2014;58(2):258-274. https://doi.org/10.1097/MPG.0000000000000266.
1. Evaluation and treatment of functional constipation in infants and children: Evidence-based recommendations from ESPGHAN-NASPGHAN. J Pediatr Gastro Nutr. 2014;58(2):258-274. https://doi.org/10.1097/MPG.0000000000000266.
1.09 Common Clinical Diagnoses and Conditions: Central Nervous System Infections
Introduction
Central nervous system (CNS) infections in children can cause significant morbidity and mortality and require prompt diagnosis and management. CNS infections include meningitis, encephalitis, infections of CNS implanted devices, parameningeal infections, spinal epidural abscesses, and others. The common infectious pathogens and predisposing risk factors vary by infection type, as do the overall severity of illness and the expected outcome. Likewise, the type and severity of infection dictates the choice of pharmacological and other therapeutic agents. To optimize outcomes, management often requires coordination of care with subspecialists, including infectious disease physicians, neurologists, neurosurgeons, and others. Pediatric hospitalists are uniquely equipped to provide both coordinated acute care and develop an integrated transition plan for post-discharge care and placement.
Knowledge
Pediatric hospitalists should be able to:
- Discuss the most common etiologic agents of different CNS infections for children of varying chronological ages and predisposing factors.
- Discuss the common presenting signs and symptoms of CNS infections, including those features that differentiate meningitis, encephalitis, parameningeal infections (including brain abscess, subdural empyema, and intracranial epidural abscess), and spinal epidural abscess, considering variation in presentation by chronological age.
- Discuss how the presence of comorbid conditions, such as immunocompromised status, implanted CNS devices, developmental delay, and others, may impact or alter some elements of the history and physical examination.
- Discuss the impact of cerebrospinal fluid (CSF) shunts on risk for CNS infection, particularly in the first month following shunt placement, as well as the indications for shunt tap, shunt externalization, and/or removal.
- Review alternative diagnoses that may mimic the presentation of CNS infection, such as autoimmune diseases involving the CNS, stroke, toxidromes, psychiatric disorders, neoplastic syndromes, and others.
- List predisposing conditions for parameningeal infections, including sinusitis, otitis media, mastoiditis, and orbital cellulitis.
- Discuss appropriate microbiologic, virologic, and serologic tests utilized to establish a diagnosis, including the use of indirect sampling from rectal or nasopharyngeal sites.
- Discuss the risks, benefits, indications, and contraindications for lumbar puncture.
- Compare and contrast CSF analysis values found in bacterial, viral, fungal, parasitic, and aseptic meningitis, encephalitis, and parameningeal infections.
- Explain the indications for imaging of children with meningitis, encephalitis, ventricular infections, and parameningeal infections, stating the modality of choice for each diagnosis.
- Compare and contrast the value of computed tomography versus magnetic resonance for diagnostic imaging of CNS infections of the head, neck, and spine, attending to sedation needs, local availability, radiation exposure, and contrast versus non-contrast images.
- Discuss initial antimicrobial therapy for CNS infections, and how this varies by age, site of infection, presence of CSF shunt, CNS drug penetration, and regional microbial drug resistance patterns.
- Describe the most common acute complications of CNS infections, including fluid and electrolyte imbalance, seizures, and increased intracranial pressure.
- Explain patient characteristics that indicate a requirement for higher level of care and/or monitoring for children with CNS infection.
- Discuss the prognosis and long-term sequelae of different CNS infections.
- Describe criteria, including specific measures of clinical stability, which must be met before discharging or transferring patients with CNS infections.
Skills
Pediatric hospitalists should be able to:
- Elicit a thorough medical history, with emphasis on elements that may distinguish between types of CNS infections.
- Perform a thorough physical examination, to elicit key features of various types of CNS infections, such as mental status changes and focal versus global neurological findings.
- Perform a lumbar puncture as indicated or coordinate lumbar puncture with appropriate subspecialists when assistance is required.
- Initiate an empiric antimicrobial regimen based on patient history, underlying comorbid conditions, and initial diagnostic testing.
- Tailor antibiotic regimens and duration of therapy based on microbiologic culture and sensitivity data, as well as the patient’s clinical condition and underlying comorbidities.
- Adhere consistently to proper infection control practices.
- Perform frequent careful reassessments, note changes in clinical status, manage acute complications, and identify indications for transfer to a higher level of care.
- Engage and coordinate consultants, such as neurologists, neurosurgeons, infectious diseases specialists, rehabilitation therapists, and others when indicated, including those whose support is required by the presence of neurological sequelae.
- Coordinate care with subspecialists and the primary care provider to arrange an appropriate transition plan for hospital discharge inclusive of therapies, school needs, and psychosocial support.
Attitudes
Pediatric hospitalists should be able to:
- Realize responsibility for sensitive and clear communications with the family/caregivers regarding diagnosis, treatment plans, and potential neurologic sequelae, engaging consultants as appropriate.
- Recognize the importance of collaboration with subspecialists and the primary care provider to ensure coordinated longitudinal care for children with CNS infections.
Systems Organization and Improvement
In order to improve efficiency and quality within their organizations, pediatric hospitalists should:
- Lead, coordinate, or participate in the development and implementation of cost-effective, safe, evidence-based care pathways to standardize the evaluation and management for hospitalized children with CNS infections.
- Advocate and work with hospital and community leaders to assure that proper services are available for children requiring short and long-term support services.
1. Tunkel AR, Glaser CA, Bloch KC, et al. The management of encephalitis: clinical practice guidelines by the Infectious Diseases Society of America. Clin Infect Dis. 2008;47(3):303-327. https://doi.org/10.1086/589747.
2. Harrison C. Focal Suppurative Infections of the Nervous System. In: Long SS, Prober CG, Fischer M, eds. Principles and Practice of Pediatric Infectious Diseases. 5th ed. Philadelphia, PA: Elsevier, 2017:329-340.
Introduction
Central nervous system (CNS) infections in children can cause significant morbidity and mortality and require prompt diagnosis and management. CNS infections include meningitis, encephalitis, infections of CNS implanted devices, parameningeal infections, spinal epidural abscesses, and others. The common infectious pathogens and predisposing risk factors vary by infection type, as do the overall severity of illness and the expected outcome. Likewise, the type and severity of infection dictates the choice of pharmacological and other therapeutic agents. To optimize outcomes, management often requires coordination of care with subspecialists, including infectious disease physicians, neurologists, neurosurgeons, and others. Pediatric hospitalists are uniquely equipped to provide both coordinated acute care and develop an integrated transition plan for post-discharge care and placement.
Knowledge
Pediatric hospitalists should be able to:
- Discuss the most common etiologic agents of different CNS infections for children of varying chronological ages and predisposing factors.
- Discuss the common presenting signs and symptoms of CNS infections, including those features that differentiate meningitis, encephalitis, parameningeal infections (including brain abscess, subdural empyema, and intracranial epidural abscess), and spinal epidural abscess, considering variation in presentation by chronological age.
- Discuss how the presence of comorbid conditions, such as immunocompromised status, implanted CNS devices, developmental delay, and others, may impact or alter some elements of the history and physical examination.
- Discuss the impact of cerebrospinal fluid (CSF) shunts on risk for CNS infection, particularly in the first month following shunt placement, as well as the indications for shunt tap, shunt externalization, and/or removal.
- Review alternative diagnoses that may mimic the presentation of CNS infection, such as autoimmune diseases involving the CNS, stroke, toxidromes, psychiatric disorders, neoplastic syndromes, and others.
- List predisposing conditions for parameningeal infections, including sinusitis, otitis media, mastoiditis, and orbital cellulitis.
- Discuss appropriate microbiologic, virologic, and serologic tests utilized to establish a diagnosis, including the use of indirect sampling from rectal or nasopharyngeal sites.
- Discuss the risks, benefits, indications, and contraindications for lumbar puncture.
- Compare and contrast CSF analysis values found in bacterial, viral, fungal, parasitic, and aseptic meningitis, encephalitis, and parameningeal infections.
- Explain the indications for imaging of children with meningitis, encephalitis, ventricular infections, and parameningeal infections, stating the modality of choice for each diagnosis.
- Compare and contrast the value of computed tomography versus magnetic resonance for diagnostic imaging of CNS infections of the head, neck, and spine, attending to sedation needs, local availability, radiation exposure, and contrast versus non-contrast images.
- Discuss initial antimicrobial therapy for CNS infections, and how this varies by age, site of infection, presence of CSF shunt, CNS drug penetration, and regional microbial drug resistance patterns.
- Describe the most common acute complications of CNS infections, including fluid and electrolyte imbalance, seizures, and increased intracranial pressure.
- Explain patient characteristics that indicate a requirement for higher level of care and/or monitoring for children with CNS infection.
- Discuss the prognosis and long-term sequelae of different CNS infections.
- Describe criteria, including specific measures of clinical stability, which must be met before discharging or transferring patients with CNS infections.
Skills
Pediatric hospitalists should be able to:
- Elicit a thorough medical history, with emphasis on elements that may distinguish between types of CNS infections.
- Perform a thorough physical examination, to elicit key features of various types of CNS infections, such as mental status changes and focal versus global neurological findings.
- Perform a lumbar puncture as indicated or coordinate lumbar puncture with appropriate subspecialists when assistance is required.
- Initiate an empiric antimicrobial regimen based on patient history, underlying comorbid conditions, and initial diagnostic testing.
- Tailor antibiotic regimens and duration of therapy based on microbiologic culture and sensitivity data, as well as the patient’s clinical condition and underlying comorbidities.
- Adhere consistently to proper infection control practices.
- Perform frequent careful reassessments, note changes in clinical status, manage acute complications, and identify indications for transfer to a higher level of care.
- Engage and coordinate consultants, such as neurologists, neurosurgeons, infectious diseases specialists, rehabilitation therapists, and others when indicated, including those whose support is required by the presence of neurological sequelae.
- Coordinate care with subspecialists and the primary care provider to arrange an appropriate transition plan for hospital discharge inclusive of therapies, school needs, and psychosocial support.
Attitudes
Pediatric hospitalists should be able to:
- Realize responsibility for sensitive and clear communications with the family/caregivers regarding diagnosis, treatment plans, and potential neurologic sequelae, engaging consultants as appropriate.
- Recognize the importance of collaboration with subspecialists and the primary care provider to ensure coordinated longitudinal care for children with CNS infections.
Systems Organization and Improvement
In order to improve efficiency and quality within their organizations, pediatric hospitalists should:
- Lead, coordinate, or participate in the development and implementation of cost-effective, safe, evidence-based care pathways to standardize the evaluation and management for hospitalized children with CNS infections.
- Advocate and work with hospital and community leaders to assure that proper services are available for children requiring short and long-term support services.
Introduction
Central nervous system (CNS) infections in children can cause significant morbidity and mortality and require prompt diagnosis and management. CNS infections include meningitis, encephalitis, infections of CNS implanted devices, parameningeal infections, spinal epidural abscesses, and others. The common infectious pathogens and predisposing risk factors vary by infection type, as do the overall severity of illness and the expected outcome. Likewise, the type and severity of infection dictates the choice of pharmacological and other therapeutic agents. To optimize outcomes, management often requires coordination of care with subspecialists, including infectious disease physicians, neurologists, neurosurgeons, and others. Pediatric hospitalists are uniquely equipped to provide both coordinated acute care and develop an integrated transition plan for post-discharge care and placement.
Knowledge
Pediatric hospitalists should be able to:
- Discuss the most common etiologic agents of different CNS infections for children of varying chronological ages and predisposing factors.
- Discuss the common presenting signs and symptoms of CNS infections, including those features that differentiate meningitis, encephalitis, parameningeal infections (including brain abscess, subdural empyema, and intracranial epidural abscess), and spinal epidural abscess, considering variation in presentation by chronological age.
- Discuss how the presence of comorbid conditions, such as immunocompromised status, implanted CNS devices, developmental delay, and others, may impact or alter some elements of the history and physical examination.
- Discuss the impact of cerebrospinal fluid (CSF) shunts on risk for CNS infection, particularly in the first month following shunt placement, as well as the indications for shunt tap, shunt externalization, and/or removal.
- Review alternative diagnoses that may mimic the presentation of CNS infection, such as autoimmune diseases involving the CNS, stroke, toxidromes, psychiatric disorders, neoplastic syndromes, and others.
- List predisposing conditions for parameningeal infections, including sinusitis, otitis media, mastoiditis, and orbital cellulitis.
- Discuss appropriate microbiologic, virologic, and serologic tests utilized to establish a diagnosis, including the use of indirect sampling from rectal or nasopharyngeal sites.
- Discuss the risks, benefits, indications, and contraindications for lumbar puncture.
- Compare and contrast CSF analysis values found in bacterial, viral, fungal, parasitic, and aseptic meningitis, encephalitis, and parameningeal infections.
- Explain the indications for imaging of children with meningitis, encephalitis, ventricular infections, and parameningeal infections, stating the modality of choice for each diagnosis.
- Compare and contrast the value of computed tomography versus magnetic resonance for diagnostic imaging of CNS infections of the head, neck, and spine, attending to sedation needs, local availability, radiation exposure, and contrast versus non-contrast images.
- Discuss initial antimicrobial therapy for CNS infections, and how this varies by age, site of infection, presence of CSF shunt, CNS drug penetration, and regional microbial drug resistance patterns.
- Describe the most common acute complications of CNS infections, including fluid and electrolyte imbalance, seizures, and increased intracranial pressure.
- Explain patient characteristics that indicate a requirement for higher level of care and/or monitoring for children with CNS infection.
- Discuss the prognosis and long-term sequelae of different CNS infections.
- Describe criteria, including specific measures of clinical stability, which must be met before discharging or transferring patients with CNS infections.
Skills
Pediatric hospitalists should be able to:
- Elicit a thorough medical history, with emphasis on elements that may distinguish between types of CNS infections.
- Perform a thorough physical examination, to elicit key features of various types of CNS infections, such as mental status changes and focal versus global neurological findings.
- Perform a lumbar puncture as indicated or coordinate lumbar puncture with appropriate subspecialists when assistance is required.
- Initiate an empiric antimicrobial regimen based on patient history, underlying comorbid conditions, and initial diagnostic testing.
- Tailor antibiotic regimens and duration of therapy based on microbiologic culture and sensitivity data, as well as the patient’s clinical condition and underlying comorbidities.
- Adhere consistently to proper infection control practices.
- Perform frequent careful reassessments, note changes in clinical status, manage acute complications, and identify indications for transfer to a higher level of care.
- Engage and coordinate consultants, such as neurologists, neurosurgeons, infectious diseases specialists, rehabilitation therapists, and others when indicated, including those whose support is required by the presence of neurological sequelae.
- Coordinate care with subspecialists and the primary care provider to arrange an appropriate transition plan for hospital discharge inclusive of therapies, school needs, and psychosocial support.
Attitudes
Pediatric hospitalists should be able to:
- Realize responsibility for sensitive and clear communications with the family/caregivers regarding diagnosis, treatment plans, and potential neurologic sequelae, engaging consultants as appropriate.
- Recognize the importance of collaboration with subspecialists and the primary care provider to ensure coordinated longitudinal care for children with CNS infections.
Systems Organization and Improvement
In order to improve efficiency and quality within their organizations, pediatric hospitalists should:
- Lead, coordinate, or participate in the development and implementation of cost-effective, safe, evidence-based care pathways to standardize the evaluation and management for hospitalized children with CNS infections.
- Advocate and work with hospital and community leaders to assure that proper services are available for children requiring short and long-term support services.
1. Tunkel AR, Glaser CA, Bloch KC, et al. The management of encephalitis: clinical practice guidelines by the Infectious Diseases Society of America. Clin Infect Dis. 2008;47(3):303-327. https://doi.org/10.1086/589747.
2. Harrison C. Focal Suppurative Infections of the Nervous System. In: Long SS, Prober CG, Fischer M, eds. Principles and Practice of Pediatric Infectious Diseases. 5th ed. Philadelphia, PA: Elsevier, 2017:329-340.
1. Tunkel AR, Glaser CA, Bloch KC, et al. The management of encephalitis: clinical practice guidelines by the Infectious Diseases Society of America. Clin Infect Dis. 2008;47(3):303-327. https://doi.org/10.1086/589747.
2. Harrison C. Focal Suppurative Infections of the Nervous System. In: Long SS, Prober CG, Fischer M, eds. Principles and Practice of Pediatric Infectious Diseases. 5th ed. Philadelphia, PA: Elsevier, 2017:329-340.
1.08 Common Clinical Diagnoses and Conditions: Bronchiolitis
Introduction
Bronchiolitis is the most common viral lower respiratory illness in young children and infants. It is responsible for hundreds of thousands of outpatient and emergency department visits and more than 100,000 hospitalizations per year, accounting for more than $1.7 billion in hospital charges annually. The most commonly identified etiology of bronchiolitis is respiratory syncytial virus (RSV), however bronchiolitis may be caused by many other viruses, including rhinovirus, human metapneumovirus, parainfluenza, adenovirus, and influenza. With hospital care provided for these patients in a variety of settings, the potential for significant variation in practices exists despite guidelines published by the American Academy of Pediatrics. Pediatric hospitalists should render evidence-based care that minimizes harm, improves outcomes, and avoids unnecessary testing, hospitalization, and treatments.
Knowledge
Pediatric hospitalists should be able to:
- Compare and contrast the epidemiology and pathogenesis of bronchiolitis with asthma.
- Describe the typical clinical signs of viral bronchiolitis (such as wheezing, rales, tachypnea, acute respiratory distress, hypoxia, cough, apnea, nasal obstruction, and others) and explain the ways in which presentations may vary.
- Discuss alternate diagnoses that may mimic bronchiolitis, such as pneumonia, congestive heart failure, previously undiagnosed cyanotic or non-cyanotic congenital heart disease, sepsis, aspiration, and others.
- Describe risk factors that predispose infants and children to severe illness or complications of bronchiolitis, including prematurity, heart disease, pulmonary disease, immunodeficiency, neuromuscular disease, and environmental smoke exposure.
- Explain indications for hospital admission and cite discharge criteria.
- Discuss indications for diagnostic testing, including viral testing and chest radiographs.
- Discuss risks of serious bacterial infection and initial diagnostic evaluations for febrile infants of various ages presenting with bronchiolitis, attending to ages less than 30 days, 31-60 days, and others.
- Explain the indications and contraindications for RSV immunoprophylaxis.
- Summarize the evidence for the use of specific therapies in the treatment of routine bronchiolitis, including beta-agonists, hypertonic saline, and steroids.
- Discuss the evidence regarding use of supportive measures, including suctioning (such as nasal-pharyngeal, oral, and others), chest physiotherapy, positioning, enteral versus intravenous fluids and nutrition, supplemental oxygen, and others.
- Define the benefits, limitations, and potential harms associated with use of various non-invasive monitoring modalities, including cardiorespiratory, oxygen saturation, and capnography.
- Discuss management strategies for patients with worsening respiratory status, including use of various oxygen delivery systems and advanced respiratory support (including heated high flow nasal cannula, forms of non-invasive ventilation, and endotracheal intubation and mechanical ventilation).
Skills
Pediatric hospitalists should be able to:
- Diagnose bronchiolitis by efficiently performing an accurate history and physical examination, determining if key features of the disease are present.
- Assess clinical signs of respiratory distress and identify impending respiratory failure.
- Identify the indications for escalating level of care, transferring to a tertiary care center, and initiation of ventilatory support.
- Assess nutrition and hydration status and choose appropriate methods to maintain adequate hydration and nutrition, with promotion of breastfeeding when appropriate.
- Order appropriate monitoring (type and frequency) and correctly interpret monitor data.
- Perform reassessments daily and as needed, note changes in clinical status, and respond with appropriate actions, including discontinuation of ineffective or unnecessary therapies and monitoring.
- Utilize standardized respiratory scores to objectively assess and document response to interventions.
- Implement appropriate oxygen weaning strategies, including the use of appropriate oxygen saturation parameters.
- Adhere to proper infection control measures and educate the family/caregivers in the importance of hand washing and minimizing environmental exposure in the prevention of infection.
- Communicate with the family/caregivers about the etiology and natural history of bronchiolitis, interpretation of clinical findings, care plans, and supportive care.
- Deliver efficient care by proactively creating a discharge plan that can be expediently activated when appropriate.
- Coordinate care with the primary care provider and other services as indicated, to arrange an appropriate transition plan for hospital discharge.
Attitudes
Pediatric hospitalists should be able to:
- Acknowledge the importance of discussing the role of supportive care and the limited evidence for other interventions with the family/caregivers.
- Exemplify a proactive, engaged attitude regarding proper isolation measures, including hand washing to prevent spread of the etiologic agent in the hospital.
- Realize responsibility for explaining the relationship between bronchiolitis and risk of future wheezing when educating the family/caregivers regarding this diagnosis.
Systems Organization and Improvement
In order to improve efficiency and quality within their organizations, pediatric hospitalists should:
- Collaborate with hospital infection control practitioners to prevent nosocomial infection related to bronchiolitis.
- Partner with community services to educate the public on respiratory infection preventive strategies.
- Lead, coordinate, or participate in multidisciplinary initiatives (including nursing, respiratory therapy, emergency department physicians, primary care physicians, intensivists, and other specialists) to develop, implement, and assess quality outcomes of evidence-based clinical guidelines for the care of children with bronchiolitis.
- Collaborate with intensivists, respiratory therapists, and nurses to mutually develop and implement evidence-based criteria for use of non-invasive respiratory support therapies such as supplemental oxygen, heated high-flow nasal cannula, and others.
1. Ralston WL, Lieberthal AS, Meissner HC. Clinical Practice Guideline: The Diagnosis, Management, and Prevention of Bronchiolitis. Pediatrics. 2014; 134(5): e1474-1502. https://pediatrics.aappublications.org/content/134/5/e1474.long. Accessed August 28, 2019.
2. National Institute for Health and Care Excellence. Bronchiolitis: diagnosis and management of bronchiolitis in children. Clinical Guideline NG 9. June 2015. https://www.nice.org.uk/guidance/ng9. Accessed August 25, 2019.
Introduction
Bronchiolitis is the most common viral lower respiratory illness in young children and infants. It is responsible for hundreds of thousands of outpatient and emergency department visits and more than 100,000 hospitalizations per year, accounting for more than $1.7 billion in hospital charges annually. The most commonly identified etiology of bronchiolitis is respiratory syncytial virus (RSV), however bronchiolitis may be caused by many other viruses, including rhinovirus, human metapneumovirus, parainfluenza, adenovirus, and influenza. With hospital care provided for these patients in a variety of settings, the potential for significant variation in practices exists despite guidelines published by the American Academy of Pediatrics. Pediatric hospitalists should render evidence-based care that minimizes harm, improves outcomes, and avoids unnecessary testing, hospitalization, and treatments.
Knowledge
Pediatric hospitalists should be able to:
- Compare and contrast the epidemiology and pathogenesis of bronchiolitis with asthma.
- Describe the typical clinical signs of viral bronchiolitis (such as wheezing, rales, tachypnea, acute respiratory distress, hypoxia, cough, apnea, nasal obstruction, and others) and explain the ways in which presentations may vary.
- Discuss alternate diagnoses that may mimic bronchiolitis, such as pneumonia, congestive heart failure, previously undiagnosed cyanotic or non-cyanotic congenital heart disease, sepsis, aspiration, and others.
- Describe risk factors that predispose infants and children to severe illness or complications of bronchiolitis, including prematurity, heart disease, pulmonary disease, immunodeficiency, neuromuscular disease, and environmental smoke exposure.
- Explain indications for hospital admission and cite discharge criteria.
- Discuss indications for diagnostic testing, including viral testing and chest radiographs.
- Discuss risks of serious bacterial infection and initial diagnostic evaluations for febrile infants of various ages presenting with bronchiolitis, attending to ages less than 30 days, 31-60 days, and others.
- Explain the indications and contraindications for RSV immunoprophylaxis.
- Summarize the evidence for the use of specific therapies in the treatment of routine bronchiolitis, including beta-agonists, hypertonic saline, and steroids.
- Discuss the evidence regarding use of supportive measures, including suctioning (such as nasal-pharyngeal, oral, and others), chest physiotherapy, positioning, enteral versus intravenous fluids and nutrition, supplemental oxygen, and others.
- Define the benefits, limitations, and potential harms associated with use of various non-invasive monitoring modalities, including cardiorespiratory, oxygen saturation, and capnography.
- Discuss management strategies for patients with worsening respiratory status, including use of various oxygen delivery systems and advanced respiratory support (including heated high flow nasal cannula, forms of non-invasive ventilation, and endotracheal intubation and mechanical ventilation).
Skills
Pediatric hospitalists should be able to:
- Diagnose bronchiolitis by efficiently performing an accurate history and physical examination, determining if key features of the disease are present.
- Assess clinical signs of respiratory distress and identify impending respiratory failure.
- Identify the indications for escalating level of care, transferring to a tertiary care center, and initiation of ventilatory support.
- Assess nutrition and hydration status and choose appropriate methods to maintain adequate hydration and nutrition, with promotion of breastfeeding when appropriate.
- Order appropriate monitoring (type and frequency) and correctly interpret monitor data.
- Perform reassessments daily and as needed, note changes in clinical status, and respond with appropriate actions, including discontinuation of ineffective or unnecessary therapies and monitoring.
- Utilize standardized respiratory scores to objectively assess and document response to interventions.
- Implement appropriate oxygen weaning strategies, including the use of appropriate oxygen saturation parameters.
- Adhere to proper infection control measures and educate the family/caregivers in the importance of hand washing and minimizing environmental exposure in the prevention of infection.
- Communicate with the family/caregivers about the etiology and natural history of bronchiolitis, interpretation of clinical findings, care plans, and supportive care.
- Deliver efficient care by proactively creating a discharge plan that can be expediently activated when appropriate.
- Coordinate care with the primary care provider and other services as indicated, to arrange an appropriate transition plan for hospital discharge.
Attitudes
Pediatric hospitalists should be able to:
- Acknowledge the importance of discussing the role of supportive care and the limited evidence for other interventions with the family/caregivers.
- Exemplify a proactive, engaged attitude regarding proper isolation measures, including hand washing to prevent spread of the etiologic agent in the hospital.
- Realize responsibility for explaining the relationship between bronchiolitis and risk of future wheezing when educating the family/caregivers regarding this diagnosis.
Systems Organization and Improvement
In order to improve efficiency and quality within their organizations, pediatric hospitalists should:
- Collaborate with hospital infection control practitioners to prevent nosocomial infection related to bronchiolitis.
- Partner with community services to educate the public on respiratory infection preventive strategies.
- Lead, coordinate, or participate in multidisciplinary initiatives (including nursing, respiratory therapy, emergency department physicians, primary care physicians, intensivists, and other specialists) to develop, implement, and assess quality outcomes of evidence-based clinical guidelines for the care of children with bronchiolitis.
- Collaborate with intensivists, respiratory therapists, and nurses to mutually develop and implement evidence-based criteria for use of non-invasive respiratory support therapies such as supplemental oxygen, heated high-flow nasal cannula, and others.
Introduction
Bronchiolitis is the most common viral lower respiratory illness in young children and infants. It is responsible for hundreds of thousands of outpatient and emergency department visits and more than 100,000 hospitalizations per year, accounting for more than $1.7 billion in hospital charges annually. The most commonly identified etiology of bronchiolitis is respiratory syncytial virus (RSV), however bronchiolitis may be caused by many other viruses, including rhinovirus, human metapneumovirus, parainfluenza, adenovirus, and influenza. With hospital care provided for these patients in a variety of settings, the potential for significant variation in practices exists despite guidelines published by the American Academy of Pediatrics. Pediatric hospitalists should render evidence-based care that minimizes harm, improves outcomes, and avoids unnecessary testing, hospitalization, and treatments.
Knowledge
Pediatric hospitalists should be able to:
- Compare and contrast the epidemiology and pathogenesis of bronchiolitis with asthma.
- Describe the typical clinical signs of viral bronchiolitis (such as wheezing, rales, tachypnea, acute respiratory distress, hypoxia, cough, apnea, nasal obstruction, and others) and explain the ways in which presentations may vary.
- Discuss alternate diagnoses that may mimic bronchiolitis, such as pneumonia, congestive heart failure, previously undiagnosed cyanotic or non-cyanotic congenital heart disease, sepsis, aspiration, and others.
- Describe risk factors that predispose infants and children to severe illness or complications of bronchiolitis, including prematurity, heart disease, pulmonary disease, immunodeficiency, neuromuscular disease, and environmental smoke exposure.
- Explain indications for hospital admission and cite discharge criteria.
- Discuss indications for diagnostic testing, including viral testing and chest radiographs.
- Discuss risks of serious bacterial infection and initial diagnostic evaluations for febrile infants of various ages presenting with bronchiolitis, attending to ages less than 30 days, 31-60 days, and others.
- Explain the indications and contraindications for RSV immunoprophylaxis.
- Summarize the evidence for the use of specific therapies in the treatment of routine bronchiolitis, including beta-agonists, hypertonic saline, and steroids.
- Discuss the evidence regarding use of supportive measures, including suctioning (such as nasal-pharyngeal, oral, and others), chest physiotherapy, positioning, enteral versus intravenous fluids and nutrition, supplemental oxygen, and others.
- Define the benefits, limitations, and potential harms associated with use of various non-invasive monitoring modalities, including cardiorespiratory, oxygen saturation, and capnography.
- Discuss management strategies for patients with worsening respiratory status, including use of various oxygen delivery systems and advanced respiratory support (including heated high flow nasal cannula, forms of non-invasive ventilation, and endotracheal intubation and mechanical ventilation).
Skills
Pediatric hospitalists should be able to:
- Diagnose bronchiolitis by efficiently performing an accurate history and physical examination, determining if key features of the disease are present.
- Assess clinical signs of respiratory distress and identify impending respiratory failure.
- Identify the indications for escalating level of care, transferring to a tertiary care center, and initiation of ventilatory support.
- Assess nutrition and hydration status and choose appropriate methods to maintain adequate hydration and nutrition, with promotion of breastfeeding when appropriate.
- Order appropriate monitoring (type and frequency) and correctly interpret monitor data.
- Perform reassessments daily and as needed, note changes in clinical status, and respond with appropriate actions, including discontinuation of ineffective or unnecessary therapies and monitoring.
- Utilize standardized respiratory scores to objectively assess and document response to interventions.
- Implement appropriate oxygen weaning strategies, including the use of appropriate oxygen saturation parameters.
- Adhere to proper infection control measures and educate the family/caregivers in the importance of hand washing and minimizing environmental exposure in the prevention of infection.
- Communicate with the family/caregivers about the etiology and natural history of bronchiolitis, interpretation of clinical findings, care plans, and supportive care.
- Deliver efficient care by proactively creating a discharge plan that can be expediently activated when appropriate.
- Coordinate care with the primary care provider and other services as indicated, to arrange an appropriate transition plan for hospital discharge.
Attitudes
Pediatric hospitalists should be able to:
- Acknowledge the importance of discussing the role of supportive care and the limited evidence for other interventions with the family/caregivers.
- Exemplify a proactive, engaged attitude regarding proper isolation measures, including hand washing to prevent spread of the etiologic agent in the hospital.
- Realize responsibility for explaining the relationship between bronchiolitis and risk of future wheezing when educating the family/caregivers regarding this diagnosis.
Systems Organization and Improvement
In order to improve efficiency and quality within their organizations, pediatric hospitalists should:
- Collaborate with hospital infection control practitioners to prevent nosocomial infection related to bronchiolitis.
- Partner with community services to educate the public on respiratory infection preventive strategies.
- Lead, coordinate, or participate in multidisciplinary initiatives (including nursing, respiratory therapy, emergency department physicians, primary care physicians, intensivists, and other specialists) to develop, implement, and assess quality outcomes of evidence-based clinical guidelines for the care of children with bronchiolitis.
- Collaborate with intensivists, respiratory therapists, and nurses to mutually develop and implement evidence-based criteria for use of non-invasive respiratory support therapies such as supplemental oxygen, heated high-flow nasal cannula, and others.
1. Ralston WL, Lieberthal AS, Meissner HC. Clinical Practice Guideline: The Diagnosis, Management, and Prevention of Bronchiolitis. Pediatrics. 2014; 134(5): e1474-1502. https://pediatrics.aappublications.org/content/134/5/e1474.long. Accessed August 28, 2019.
2. National Institute for Health and Care Excellence. Bronchiolitis: diagnosis and management of bronchiolitis in children. Clinical Guideline NG 9. June 2015. https://www.nice.org.uk/guidance/ng9. Accessed August 25, 2019.
1. Ralston WL, Lieberthal AS, Meissner HC. Clinical Practice Guideline: The Diagnosis, Management, and Prevention of Bronchiolitis. Pediatrics. 2014; 134(5): e1474-1502. https://pediatrics.aappublications.org/content/134/5/e1474.long. Accessed August 28, 2019.
2. National Institute for Health and Care Excellence. Bronchiolitis: diagnosis and management of bronchiolitis in children. Clinical Guideline NG 9. June 2015. https://www.nice.org.uk/guidance/ng9. Accessed August 25, 2019.
1.07 Common Clinical Diagnoses and Conditions: Brief Resolved Unexplained Event
Introduction
A Brief Resolved Unexplained Event (BRUE) is defined as an event occurring in an infant younger than 1 year during which the observer reports a sudden, brief, and now resolved episode which includes one or more of the following: cyanosis or pallor; absent, decreased, or irregular breathing; marked change in tone (hyper- or hypotonia); and altered level of responsiveness, and after a thorough history and physical examination an explanation is unable to be identified. BRUE is a more specific term that replaces the previously used term Apparent Life-Threatening Event (ALTE). Patients experiencing a BRUE are categorized into lower- and higher-risk groups based on event and patient characteristics. While patients in the lower-risk group generally do not require hospitalization, those in the higher-risk group may benefit from admission for observation of events and/or completion of a targeted evaluation. Given that a BRUE can be caused by a wide variety of disorders, most self-limiting and non-life threatening, pediatric hospitalists are uniquely positioned to lead a step-wise and systematic evaluation, involving testing and subspecialists as indicated.
Knowledge
Pediatric hospitalists should be able to:
- Describe the symptoms and signs that define a BRUE and compare and contrast the criteria for lower-risk and higher-risk categorization.
- Compare and contrast the differences between Sudden Infant Death Syndrome (SIDS) and BRUE, clarifying that they are unrelated entities.
- Discuss key diagnoses and their associated historical or physical exam findings, that should be considered when evaluating a child diagnosed with a BRUE, such as oral dysphagia, gastroesophageal reflux, seizure, apnea of prematurity, infection (including sepsis, meningitis, pertussis, and bronchiolitis), toxin exposure, cardiac dysfunction, obstructive apnea, inborn errors of metabolism, central hypoventilation syndrome, hydrocephalus, child abuse, and others.
- Discuss types of child abuse (including neglect, poisoning, medical child abuse, and abusive head trauma) presenting as a BRUE and history and physical examination findings that should increase suspicion for this etiology.
- Discuss the indication for and goals of hospitalization (including monitoring, diagnosis, treatment, reassurance, and education), as well as potential risks (including increased anxiety of the family/caregivers, false positive testing, and nosocomial infections).
- Discuss the role of diagnostic testing in the evaluation of children presenting with BRUE and the clinical factors that may warrant additional management.
- Describe indications for subspecialty consultation for evaluation and treatment of children diagnosed with BRUE.
- Describe criteria and care coordination steps that must be met before discharge of patients with BRUE.
Skills
Pediatric hospitalists should be able to:
- Communicate effectively with the referring provider about the role of and criteria for hospitalization, emphasizing principles of evidenced-based medicine and high value care.
- Obtain an accurate patient history and perform a thorough physical examination, eliciting features to fully characterize the event.
- Categorize the event as a lower- or higher-risk BRUE.
- Critically assess the level of evidence and risk/benefit ratio for the evaluation and management of lower-risk patients with BRUE.
- Interpret diagnostic tests (such as laboratory tests, chest x-rays, and electrocardiograms) and identify abnormal findings that require further testing or consultation.
- Order appropriate monitoring and correctly interpret monitor data.
- Perform careful reassessments daily and as needed, note changes in clinical status and test results, and respond with appropriate actions.
- Engage consultants and support staff (such as subspecialists, feeding specialists, and social workers) efficiently when indicated.
- Communicate effectively with the family/caregivers and healthcare providers regarding findings and care plans, with special focus on aligning recommendations with current literature, especially as it relates to the usefulness of home monitoring.
- Coordinate care with the primary care provider and other providers to arrange an appropriate transition plan for hospital discharge.
Attitudes
Pediatric hospitalists should be able to:
- Realize responsibility for effective communication with the family/caregivers and healthcare providers regarding findings and care plans.
- Realize the importance of clarifying that SIDS and BRUE are different entities, addressing common confusion among the family/caregivers, hospital staff, and learners.
- Realize the impact of a BRUE on the family/caregivers and the implications for discharge planning and follow-up.
- Exemplify professional behavior when addressing issues related to anxiety of the family/caregivers, home safety, and social determinants of health.
Systems Organization and Improvement
In order to improve efficiency and quality within their organizations, pediatric hospitalists should:
- Lead, coordinate, or participate in multidisciplinary initiatives to develop and implement evidence-based clinical guidelines to improve quality of care for infants with BRUE.
1. Tieder JS, Bonkowsky JL, Etzel RA, et al. Brief resolved unexplained events (formerly apparent life-threatening events) and evaluation of lower-risk infants. Pediatrics. 2016;137(5):e20160590. https://www.ncbi.nlm.nih.gov/pubmed/27244835 . Accessed August 28, 2019.
2. Merritt JL 2nd, Quinonez RA, Bonkowsky JL, et al. A framework for evaluation of the higher-risk infant after a brief resolved unexplained event. Pediatrics. 2019;144(2): e20184101. https://pediatrics.aappublications.org/content/144/2/e20184101 Accessed August 28, 2019.
Introduction
A Brief Resolved Unexplained Event (BRUE) is defined as an event occurring in an infant younger than 1 year during which the observer reports a sudden, brief, and now resolved episode which includes one or more of the following: cyanosis or pallor; absent, decreased, or irregular breathing; marked change in tone (hyper- or hypotonia); and altered level of responsiveness, and after a thorough history and physical examination an explanation is unable to be identified. BRUE is a more specific term that replaces the previously used term Apparent Life-Threatening Event (ALTE). Patients experiencing a BRUE are categorized into lower- and higher-risk groups based on event and patient characteristics. While patients in the lower-risk group generally do not require hospitalization, those in the higher-risk group may benefit from admission for observation of events and/or completion of a targeted evaluation. Given that a BRUE can be caused by a wide variety of disorders, most self-limiting and non-life threatening, pediatric hospitalists are uniquely positioned to lead a step-wise and systematic evaluation, involving testing and subspecialists as indicated.
Knowledge
Pediatric hospitalists should be able to:
- Describe the symptoms and signs that define a BRUE and compare and contrast the criteria for lower-risk and higher-risk categorization.
- Compare and contrast the differences between Sudden Infant Death Syndrome (SIDS) and BRUE, clarifying that they are unrelated entities.
- Discuss key diagnoses and their associated historical or physical exam findings, that should be considered when evaluating a child diagnosed with a BRUE, such as oral dysphagia, gastroesophageal reflux, seizure, apnea of prematurity, infection (including sepsis, meningitis, pertussis, and bronchiolitis), toxin exposure, cardiac dysfunction, obstructive apnea, inborn errors of metabolism, central hypoventilation syndrome, hydrocephalus, child abuse, and others.
- Discuss types of child abuse (including neglect, poisoning, medical child abuse, and abusive head trauma) presenting as a BRUE and history and physical examination findings that should increase suspicion for this etiology.
- Discuss the indication for and goals of hospitalization (including monitoring, diagnosis, treatment, reassurance, and education), as well as potential risks (including increased anxiety of the family/caregivers, false positive testing, and nosocomial infections).
- Discuss the role of diagnostic testing in the evaluation of children presenting with BRUE and the clinical factors that may warrant additional management.
- Describe indications for subspecialty consultation for evaluation and treatment of children diagnosed with BRUE.
- Describe criteria and care coordination steps that must be met before discharge of patients with BRUE.
Skills
Pediatric hospitalists should be able to:
- Communicate effectively with the referring provider about the role of and criteria for hospitalization, emphasizing principles of evidenced-based medicine and high value care.
- Obtain an accurate patient history and perform a thorough physical examination, eliciting features to fully characterize the event.
- Categorize the event as a lower- or higher-risk BRUE.
- Critically assess the level of evidence and risk/benefit ratio for the evaluation and management of lower-risk patients with BRUE.
- Interpret diagnostic tests (such as laboratory tests, chest x-rays, and electrocardiograms) and identify abnormal findings that require further testing or consultation.
- Order appropriate monitoring and correctly interpret monitor data.
- Perform careful reassessments daily and as needed, note changes in clinical status and test results, and respond with appropriate actions.
- Engage consultants and support staff (such as subspecialists, feeding specialists, and social workers) efficiently when indicated.
- Communicate effectively with the family/caregivers and healthcare providers regarding findings and care plans, with special focus on aligning recommendations with current literature, especially as it relates to the usefulness of home monitoring.
- Coordinate care with the primary care provider and other providers to arrange an appropriate transition plan for hospital discharge.
Attitudes
Pediatric hospitalists should be able to:
- Realize responsibility for effective communication with the family/caregivers and healthcare providers regarding findings and care plans.
- Realize the importance of clarifying that SIDS and BRUE are different entities, addressing common confusion among the family/caregivers, hospital staff, and learners.
- Realize the impact of a BRUE on the family/caregivers and the implications for discharge planning and follow-up.
- Exemplify professional behavior when addressing issues related to anxiety of the family/caregivers, home safety, and social determinants of health.
Systems Organization and Improvement
In order to improve efficiency and quality within their organizations, pediatric hospitalists should:
- Lead, coordinate, or participate in multidisciplinary initiatives to develop and implement evidence-based clinical guidelines to improve quality of care for infants with BRUE.
Introduction
A Brief Resolved Unexplained Event (BRUE) is defined as an event occurring in an infant younger than 1 year during which the observer reports a sudden, brief, and now resolved episode which includes one or more of the following: cyanosis or pallor; absent, decreased, or irregular breathing; marked change in tone (hyper- or hypotonia); and altered level of responsiveness, and after a thorough history and physical examination an explanation is unable to be identified. BRUE is a more specific term that replaces the previously used term Apparent Life-Threatening Event (ALTE). Patients experiencing a BRUE are categorized into lower- and higher-risk groups based on event and patient characteristics. While patients in the lower-risk group generally do not require hospitalization, those in the higher-risk group may benefit from admission for observation of events and/or completion of a targeted evaluation. Given that a BRUE can be caused by a wide variety of disorders, most self-limiting and non-life threatening, pediatric hospitalists are uniquely positioned to lead a step-wise and systematic evaluation, involving testing and subspecialists as indicated.
Knowledge
Pediatric hospitalists should be able to:
- Describe the symptoms and signs that define a BRUE and compare and contrast the criteria for lower-risk and higher-risk categorization.
- Compare and contrast the differences between Sudden Infant Death Syndrome (SIDS) and BRUE, clarifying that they are unrelated entities.
- Discuss key diagnoses and their associated historical or physical exam findings, that should be considered when evaluating a child diagnosed with a BRUE, such as oral dysphagia, gastroesophageal reflux, seizure, apnea of prematurity, infection (including sepsis, meningitis, pertussis, and bronchiolitis), toxin exposure, cardiac dysfunction, obstructive apnea, inborn errors of metabolism, central hypoventilation syndrome, hydrocephalus, child abuse, and others.
- Discuss types of child abuse (including neglect, poisoning, medical child abuse, and abusive head trauma) presenting as a BRUE and history and physical examination findings that should increase suspicion for this etiology.
- Discuss the indication for and goals of hospitalization (including monitoring, diagnosis, treatment, reassurance, and education), as well as potential risks (including increased anxiety of the family/caregivers, false positive testing, and nosocomial infections).
- Discuss the role of diagnostic testing in the evaluation of children presenting with BRUE and the clinical factors that may warrant additional management.
- Describe indications for subspecialty consultation for evaluation and treatment of children diagnosed with BRUE.
- Describe criteria and care coordination steps that must be met before discharge of patients with BRUE.
Skills
Pediatric hospitalists should be able to:
- Communicate effectively with the referring provider about the role of and criteria for hospitalization, emphasizing principles of evidenced-based medicine and high value care.
- Obtain an accurate patient history and perform a thorough physical examination, eliciting features to fully characterize the event.
- Categorize the event as a lower- or higher-risk BRUE.
- Critically assess the level of evidence and risk/benefit ratio for the evaluation and management of lower-risk patients with BRUE.
- Interpret diagnostic tests (such as laboratory tests, chest x-rays, and electrocardiograms) and identify abnormal findings that require further testing or consultation.
- Order appropriate monitoring and correctly interpret monitor data.
- Perform careful reassessments daily and as needed, note changes in clinical status and test results, and respond with appropriate actions.
- Engage consultants and support staff (such as subspecialists, feeding specialists, and social workers) efficiently when indicated.
- Communicate effectively with the family/caregivers and healthcare providers regarding findings and care plans, with special focus on aligning recommendations with current literature, especially as it relates to the usefulness of home monitoring.
- Coordinate care with the primary care provider and other providers to arrange an appropriate transition plan for hospital discharge.
Attitudes
Pediatric hospitalists should be able to:
- Realize responsibility for effective communication with the family/caregivers and healthcare providers regarding findings and care plans.
- Realize the importance of clarifying that SIDS and BRUE are different entities, addressing common confusion among the family/caregivers, hospital staff, and learners.
- Realize the impact of a BRUE on the family/caregivers and the implications for discharge planning and follow-up.
- Exemplify professional behavior when addressing issues related to anxiety of the family/caregivers, home safety, and social determinants of health.
Systems Organization and Improvement
In order to improve efficiency and quality within their organizations, pediatric hospitalists should:
- Lead, coordinate, or participate in multidisciplinary initiatives to develop and implement evidence-based clinical guidelines to improve quality of care for infants with BRUE.
1. Tieder JS, Bonkowsky JL, Etzel RA, et al. Brief resolved unexplained events (formerly apparent life-threatening events) and evaluation of lower-risk infants. Pediatrics. 2016;137(5):e20160590. https://www.ncbi.nlm.nih.gov/pubmed/27244835 . Accessed August 28, 2019.
2. Merritt JL 2nd, Quinonez RA, Bonkowsky JL, et al. A framework for evaluation of the higher-risk infant after a brief resolved unexplained event. Pediatrics. 2019;144(2): e20184101. https://pediatrics.aappublications.org/content/144/2/e20184101 Accessed August 28, 2019.
1. Tieder JS, Bonkowsky JL, Etzel RA, et al. Brief resolved unexplained events (formerly apparent life-threatening events) and evaluation of lower-risk infants. Pediatrics. 2016;137(5):e20160590. https://www.ncbi.nlm.nih.gov/pubmed/27244835 . Accessed August 28, 2019.
2. Merritt JL 2nd, Quinonez RA, Bonkowsky JL, et al. A framework for evaluation of the higher-risk infant after a brief resolved unexplained event. Pediatrics. 2019;144(2): e20184101. https://pediatrics.aappublications.org/content/144/2/e20184101 Accessed August 28, 2019.
1.06 Common Clinical Diagnoses and Conditions: Bone and Joint Infections
Introduction
Osteomyelitis is a pyogenic infection of the bone or periosteum, whereas septic arthritis is an infection of the joint space. In children, these most commonly result from hematogenous spread. Osteomyelitis may also result from extension of contiguous skin or muscle infection. Septic arthritis may also result from either contiguous bone infection or direct inoculation of bacteria into the joint from penetrating trauma, intra-articular injection, or other causes. Either site of infection may represent a medical emergency in children. Bone and joint infections are commonly caused by Staphylococcus aureus, Streptococcus species, Kingella kingae, and Salmonella species. They most commonly occur in children <5 years of age. Males are nearly twice as likely to be affected as females. Prompt recognition and appropriate treatment are essential to reduce the risk of significant complications, including permanent bone or cartilage destruction with life-long disability. Pediatric hospitalists should render evidence-based care that minimizes harm, improves outcomes, and avoids use of unnecessary procedures and treatments.
Knowledge
Pediatric hospitalists should be able to:
- Discuss the differential diagnosis of common presenting signs and symptoms of bone and joint infections, including swollen joint, limp, and pain or limited movement of the affected bone or joint.
- Explain the pathophysiology of bone and joint infections.
- Compare and contrast the different clinical presentations of bone and joint infections between children of varying chronological ages.
- Explain risk factors for bone and joint infections, including sickle cell disease.
- Identify indications for admission to the hospital and goals for therapy while hospitalized for children with suspected osteomyelitis and septic arthritis.
- Classify the most likely pathogens based on age, underlying risk factors, and exposures and list appropriate antimicrobial agents for each.
- State relative local antimicrobial resistance rates for the most common organisms and explain the importance of these in prescribing therapy.
- Describe the relative advantages, disadvantages, and local availability of commonly used laboratory tests (such as C-reactive protein, blood cultures, bone aspirate, and others) and radiologic modalities (such as plain film, computed tomography, bone scan, magnetic resonance imaging, and others) in the evaluation of bone and joint infections.
- Identify risk factors for poor outcomes, including leg length discrepancy or chronic infection.
- Describe a comprehensive approach to pain management in children with bone and joint infections, including the roles of child life, occupational therapy, the pain service, and others according to local context.
- Discuss the relative advantages and disadvantages of intravenous versus oral antibiotic administration at discharge and identify the rare circumstances in which intravenous antibiotic therapy may be preferred.
- Define the role of the orthopedic surgeon and infectious diseases subspecialists in consultation, co-management, and follow-up care.
- Discuss criteria for patient transfer to a referral center in cases requiring pediatric-specific services not available at the local facility.
- Describe criteria, including specific measures of clinical improvement, antimicrobial treatment plan, and post-discharge management plan, which must be met before discharging patients with bone and joint infections.
Skills
Pediatric hospitalists should be able to:
- Diagnose osteomyelitis or septic arthritis by efficiently performing an accurate history and physical examination.
- Develop a cost-effective approach to diagnostic evaluation for children suspected of having a bone or joint infection, including laboratory and radiographic testing.
- Interpret laboratory and radiographic studies commonly ordered to assess for bone and joint infections.
- Manage pain effectively for children with bone and joint infections.
- Engage consultants (such as orthopedic surgeons, infectious disease specialists, physical therapists, and others) in a timely and effective manner when indicated.
- Access and arrange for pediatric home care services as appropriate.
- Coordinate care with subspecialists and the primary care provider and arrange an appropriate transition plan for hospital discharge.
Attitudes
Pediatric hospitalists should be able to:
- Acknowledge the need for effective communication with patients, the family/caregivers, and healthcare providers regarding findings and care plans.
- Collaborate with subspecialists and the primary care provider to ensure coordinated, longitudinal care for children with bone and joint infections.
Systems Organization and Improvement
In order to improve efficiency and quality within their organizations, pediatric hospitalists should:
- Lead, coordinate, or participate in the development and implementation of cost-effective, safe, evidence-based care pathways to standardize the evaluation and management for hospitalized children with bone and joint infections.
- Work with hospital administration to build a multidisciplinary team that can provide high value care to children with bone and joint infections, including nursing, social work, physical therapy, pharmacy, and care coordinators.
- Assist in creating systems to evaluate and improve pain management for children hospitalized with bone and joint infections.
- Lead, coordinate, or participate in efforts to increase pediatric-specific community health care resources that allow for an efficient transition to outpatient therapy and management after inpatient goals are achieved.
1. Keren R, Shah SS, Srivastava R, et al. Comparative effectiveness of intravenous vs. oral antibiotics for postdischarge treatment of acute osteomyelitis in children. JAMA Pediatr. 2015;169(2):120-128. https://doi.org/10.1001/jamapediatrics.2014.2822.
Introduction
Osteomyelitis is a pyogenic infection of the bone or periosteum, whereas septic arthritis is an infection of the joint space. In children, these most commonly result from hematogenous spread. Osteomyelitis may also result from extension of contiguous skin or muscle infection. Septic arthritis may also result from either contiguous bone infection or direct inoculation of bacteria into the joint from penetrating trauma, intra-articular injection, or other causes. Either site of infection may represent a medical emergency in children. Bone and joint infections are commonly caused by Staphylococcus aureus, Streptococcus species, Kingella kingae, and Salmonella species. They most commonly occur in children <5 years of age. Males are nearly twice as likely to be affected as females. Prompt recognition and appropriate treatment are essential to reduce the risk of significant complications, including permanent bone or cartilage destruction with life-long disability. Pediatric hospitalists should render evidence-based care that minimizes harm, improves outcomes, and avoids use of unnecessary procedures and treatments.
Knowledge
Pediatric hospitalists should be able to:
- Discuss the differential diagnosis of common presenting signs and symptoms of bone and joint infections, including swollen joint, limp, and pain or limited movement of the affected bone or joint.
- Explain the pathophysiology of bone and joint infections.
- Compare and contrast the different clinical presentations of bone and joint infections between children of varying chronological ages.
- Explain risk factors for bone and joint infections, including sickle cell disease.
- Identify indications for admission to the hospital and goals for therapy while hospitalized for children with suspected osteomyelitis and septic arthritis.
- Classify the most likely pathogens based on age, underlying risk factors, and exposures and list appropriate antimicrobial agents for each.
- State relative local antimicrobial resistance rates for the most common organisms and explain the importance of these in prescribing therapy.
- Describe the relative advantages, disadvantages, and local availability of commonly used laboratory tests (such as C-reactive protein, blood cultures, bone aspirate, and others) and radiologic modalities (such as plain film, computed tomography, bone scan, magnetic resonance imaging, and others) in the evaluation of bone and joint infections.
- Identify risk factors for poor outcomes, including leg length discrepancy or chronic infection.
- Describe a comprehensive approach to pain management in children with bone and joint infections, including the roles of child life, occupational therapy, the pain service, and others according to local context.
- Discuss the relative advantages and disadvantages of intravenous versus oral antibiotic administration at discharge and identify the rare circumstances in which intravenous antibiotic therapy may be preferred.
- Define the role of the orthopedic surgeon and infectious diseases subspecialists in consultation, co-management, and follow-up care.
- Discuss criteria for patient transfer to a referral center in cases requiring pediatric-specific services not available at the local facility.
- Describe criteria, including specific measures of clinical improvement, antimicrobial treatment plan, and post-discharge management plan, which must be met before discharging patients with bone and joint infections.
Skills
Pediatric hospitalists should be able to:
- Diagnose osteomyelitis or septic arthritis by efficiently performing an accurate history and physical examination.
- Develop a cost-effective approach to diagnostic evaluation for children suspected of having a bone or joint infection, including laboratory and radiographic testing.
- Interpret laboratory and radiographic studies commonly ordered to assess for bone and joint infections.
- Manage pain effectively for children with bone and joint infections.
- Engage consultants (such as orthopedic surgeons, infectious disease specialists, physical therapists, and others) in a timely and effective manner when indicated.
- Access and arrange for pediatric home care services as appropriate.
- Coordinate care with subspecialists and the primary care provider and arrange an appropriate transition plan for hospital discharge.
Attitudes
Pediatric hospitalists should be able to:
- Acknowledge the need for effective communication with patients, the family/caregivers, and healthcare providers regarding findings and care plans.
- Collaborate with subspecialists and the primary care provider to ensure coordinated, longitudinal care for children with bone and joint infections.
Systems Organization and Improvement
In order to improve efficiency and quality within their organizations, pediatric hospitalists should:
- Lead, coordinate, or participate in the development and implementation of cost-effective, safe, evidence-based care pathways to standardize the evaluation and management for hospitalized children with bone and joint infections.
- Work with hospital administration to build a multidisciplinary team that can provide high value care to children with bone and joint infections, including nursing, social work, physical therapy, pharmacy, and care coordinators.
- Assist in creating systems to evaluate and improve pain management for children hospitalized with bone and joint infections.
- Lead, coordinate, or participate in efforts to increase pediatric-specific community health care resources that allow for an efficient transition to outpatient therapy and management after inpatient goals are achieved.
Introduction
Osteomyelitis is a pyogenic infection of the bone or periosteum, whereas septic arthritis is an infection of the joint space. In children, these most commonly result from hematogenous spread. Osteomyelitis may also result from extension of contiguous skin or muscle infection. Septic arthritis may also result from either contiguous bone infection or direct inoculation of bacteria into the joint from penetrating trauma, intra-articular injection, or other causes. Either site of infection may represent a medical emergency in children. Bone and joint infections are commonly caused by Staphylococcus aureus, Streptococcus species, Kingella kingae, and Salmonella species. They most commonly occur in children <5 years of age. Males are nearly twice as likely to be affected as females. Prompt recognition and appropriate treatment are essential to reduce the risk of significant complications, including permanent bone or cartilage destruction with life-long disability. Pediatric hospitalists should render evidence-based care that minimizes harm, improves outcomes, and avoids use of unnecessary procedures and treatments.
Knowledge
Pediatric hospitalists should be able to:
- Discuss the differential diagnosis of common presenting signs and symptoms of bone and joint infections, including swollen joint, limp, and pain or limited movement of the affected bone or joint.
- Explain the pathophysiology of bone and joint infections.
- Compare and contrast the different clinical presentations of bone and joint infections between children of varying chronological ages.
- Explain risk factors for bone and joint infections, including sickle cell disease.
- Identify indications for admission to the hospital and goals for therapy while hospitalized for children with suspected osteomyelitis and septic arthritis.
- Classify the most likely pathogens based on age, underlying risk factors, and exposures and list appropriate antimicrobial agents for each.
- State relative local antimicrobial resistance rates for the most common organisms and explain the importance of these in prescribing therapy.
- Describe the relative advantages, disadvantages, and local availability of commonly used laboratory tests (such as C-reactive protein, blood cultures, bone aspirate, and others) and radiologic modalities (such as plain film, computed tomography, bone scan, magnetic resonance imaging, and others) in the evaluation of bone and joint infections.
- Identify risk factors for poor outcomes, including leg length discrepancy or chronic infection.
- Describe a comprehensive approach to pain management in children with bone and joint infections, including the roles of child life, occupational therapy, the pain service, and others according to local context.
- Discuss the relative advantages and disadvantages of intravenous versus oral antibiotic administration at discharge and identify the rare circumstances in which intravenous antibiotic therapy may be preferred.
- Define the role of the orthopedic surgeon and infectious diseases subspecialists in consultation, co-management, and follow-up care.
- Discuss criteria for patient transfer to a referral center in cases requiring pediatric-specific services not available at the local facility.
- Describe criteria, including specific measures of clinical improvement, antimicrobial treatment plan, and post-discharge management plan, which must be met before discharging patients with bone and joint infections.
Skills
Pediatric hospitalists should be able to:
- Diagnose osteomyelitis or septic arthritis by efficiently performing an accurate history and physical examination.
- Develop a cost-effective approach to diagnostic evaluation for children suspected of having a bone or joint infection, including laboratory and radiographic testing.
- Interpret laboratory and radiographic studies commonly ordered to assess for bone and joint infections.
- Manage pain effectively for children with bone and joint infections.
- Engage consultants (such as orthopedic surgeons, infectious disease specialists, physical therapists, and others) in a timely and effective manner when indicated.
- Access and arrange for pediatric home care services as appropriate.
- Coordinate care with subspecialists and the primary care provider and arrange an appropriate transition plan for hospital discharge.
Attitudes
Pediatric hospitalists should be able to:
- Acknowledge the need for effective communication with patients, the family/caregivers, and healthcare providers regarding findings and care plans.
- Collaborate with subspecialists and the primary care provider to ensure coordinated, longitudinal care for children with bone and joint infections.
Systems Organization and Improvement
In order to improve efficiency and quality within their organizations, pediatric hospitalists should:
- Lead, coordinate, or participate in the development and implementation of cost-effective, safe, evidence-based care pathways to standardize the evaluation and management for hospitalized children with bone and joint infections.
- Work with hospital administration to build a multidisciplinary team that can provide high value care to children with bone and joint infections, including nursing, social work, physical therapy, pharmacy, and care coordinators.
- Assist in creating systems to evaluate and improve pain management for children hospitalized with bone and joint infections.
- Lead, coordinate, or participate in efforts to increase pediatric-specific community health care resources that allow for an efficient transition to outpatient therapy and management after inpatient goals are achieved.
1. Keren R, Shah SS, Srivastava R, et al. Comparative effectiveness of intravenous vs. oral antibiotics for postdischarge treatment of acute osteomyelitis in children. JAMA Pediatr. 2015;169(2):120-128. https://doi.org/10.1001/jamapediatrics.2014.2822.
1. Keren R, Shah SS, Srivastava R, et al. Comparative effectiveness of intravenous vs. oral antibiotics for postdischarge treatment of acute osteomyelitis in children. JAMA Pediatr. 2015;169(2):120-128. https://doi.org/10.1001/jamapediatrics.2014.2822.
1.05 Common Clinical Diagnoses and Conditions: Asthma
Introduction
Asthma is one of the most common, non-communicable, chronic childhood diseases. It is a leading cause of healthcare utilization resulting in a significant number of primary care visits, emergency room visits, and hospitalizations. It has direct impact on patient quality of life with a heavy financial burden to individuals and society. The prevalence of asthma continues to rise and is not equally distributed throughout the population, differing by sex, race, socioeconomic level, and geographic location. The Department of Health and Human Services (DHHS) recognizes the weight of asthma disease on our society, having directed the National Institute of Health to create evidence-based guidelines for asthma care. Additionally, the DHHS continues to recognize asthma as a key element of the Healthy People 2020 initiative with several specific health objectives related directly to inpatient management. Due to the chronic nature of this disease, pediatric hospitalists should not only treat acute exacerbations resulting in status asthmaticus, but also create or reaffirm long-term management plans.
Knowledge
Pediatric hospitalists should be able to:
- Discuss the pathophysiology of asthma addressing both bronchoconstrictive and inflammatory components, and state how each impact pharmacologic treatment choices.
- Compare and contrast the pathophysiology of asthma with other common small airway illnesses in children, such as bronchiolitis, viral pneumonia with bronchospasm, or chronic lung disease.
- Describe disparities in asthma prevalence by sex, race, socioeconomic level, and geographic location.
- Discuss the role psychosocial factors (such as housing, parental mental health, financial status, lack of health insurance, and others) play in the risk for exposure to allergens, non-compliance to medical regimens, and access to health care.
- List the differential diagnosis of wheezing for various age groups and delineate the defining features leading to a diagnosis of asthma.
- Define asthma groups by symptom severity and frequency based on current classification guidelines.
- Discuss the impact of risk factors, exacerbating factors, and chronic comorbidities on morbidity, treatment, and prognosis.
- List common asthma triggers and explain the importance of trigger avoidance and environmental controls in minimizing the frequency and severity of asthma exacerbations.
- State the basic pharmacology, safety profile, and potential adverse effects of commonly used medications, including bronchodilators, leukotriene modifiers, inhaled or systemic corticosteroids, and magnesium sulfate
- Compare and contrast indications for the use of high dose bronchodilator therapy via multiple meter dose inhaler or continuous nebulized albuterol.
- Describe the different formulations of systemic corticosteroids commonly used for treatment of acute asthma exacerbation and the indications for each.
- Describe the utility of alternate therapies such as magnesium sulfate for acute refractory asthma.
- Cite the common complications of asthma or asthma treatment, including pneumothorax, atelectasis, lobar collapse, respiratory failure, poor cardiac output, dysrhythmias, and others.
- Describe the utility of using asthma management plans to both monitor and treat asthma via early symptom recognition, pulmonary function testing (spirometry and/or peak flow), and proper use of controller and reliever medications.
- Discuss the goals of asthma management, including the maintenance of normal activity levels (including physical activity, uninterrupted sleep, and school attendance) and pulmonary function; the prevention of chronic symptoms, recurrent exacerbations, and hospitalizations; and the provision of optimal pharmacotherapy, while minimizing adverse events.
- List specific indications for referral to an asthma subspecialist.
Skills
Pediatric hospitalists should be able to:
- Diagnose and correctly classify asthma by efficiently performing an accurate history and physical examination.
- Assess clinical findings to determine the need for hospitalization and the appropriate level of care.
- Direct an evidence-based treatment plan for status asthmaticus.
- Identify and respond to side effects associated with asthma medications.
- Order and interpret objective measures of pulmonary function, including peak flow monitoring and spirometry.
- Order and interpret results of basic diagnostic tools, such as chest radiograph, blood gas, and others as indicated.
- Order appropriate monitoring and correctly interpret monitor data.
- Provide supplemental oxygen therapy and advanced airway management as necessary.
- Recognize signs and symptoms of serious complications of asthma, including pneumothorax or impending respiratory failure.
- Facilitate an effective transfer to a tertiary care center or intensive care setting when appropriate.
- Assess disease severity and modify the daily medication regimen based upon accurate assessment of changes in disease state, both for inpatient management and transition to home.
- Assess psychosocial factors that may impact care plans and provide appropriate interventions, including support, education, and referral to available resources.
- Initiate asthma education for patients and the family/caregivers as soon after admission as possible, as appropriate for the clinical context.
- Create a discharge plan that can be expediently activated when appropriate.
- Coordinate care with the primary care provider with a plan inclusive of discharge medications, home instructions, and follow-up plans.
- Complete a written asthma action plan and use it to educate patients and the family/caregivers on trigger avoidance, medication adherence, and disease control.
Attitudes
Pediatric hospitalists should be able to:
- Reinforce the role and responsibility of patients and the family/caregivers regarding self-care, recognition of symptoms, and disease management.
- Realize responsibility for effective communication with patients, the family/caregivers, and healthcare providers regarding care plans.
- Engage in a multi-disciplinary approach to the prevention, diagnosis, and treatment of asthma, involving when appropriate, social workers or case managers, respiratory therapists, and subspecialists.
- Collaborate with primary care providers and subspecialists to ensure coordinated longitudinal care for children with asthma.
Systems Organization and Improvement
In order to improve efficiency and quality within their organizations, pediatric hospitalists should:
- Lead, coordinate, or participate in local and national initiatives to further the development and implementation of evidence-based clinical guidelines to promote effective resource utilization and improve quality of care for hospitalized children with asthma.
- Work with hospital administrators to implement and utilize performance feedback and quality improvement measures to assess outcomes of instituted guidelines for the management of inpatient asthma.
- Collaborate with primary care providers, subspecialists, social workers, and case managers to ensure a smooth transition to the outpatient setting, and to minimize the need for readmission.
1. U.S. Department of Health and Human Services, National Institutes of Health. Expert Panel Report 3: Guidelines for the Diagnosis and Management of Asthma (EPR-3). 2007 Edition. http://www.nhlbi.nih.gov/health-pro/guidelines/current/asthma-guidelines. Accessed August 22, 2019.
2. Jones BP, Fleming GM, Otillio JK, Asokan I, Arnold DH. Pediatric acute asthma exacerbations: Evaluation and management from emergency department to intensive care unit. J Asthma. 2016;53(6):607-617. https://doi.org/10.3109/02770903.2015.1067323.
3. Saglani S, Fleming L, Sonnappa S, and Bush A. Advances in the aetiology, management, and prevention of acute asthma attacks in children. Lancet Child Adol Health. 2019;3(5):354-364. https://doi.org/10.1016/S2352-4642(19)30025-2.
Introduction
Asthma is one of the most common, non-communicable, chronic childhood diseases. It is a leading cause of healthcare utilization resulting in a significant number of primary care visits, emergency room visits, and hospitalizations. It has direct impact on patient quality of life with a heavy financial burden to individuals and society. The prevalence of asthma continues to rise and is not equally distributed throughout the population, differing by sex, race, socioeconomic level, and geographic location. The Department of Health and Human Services (DHHS) recognizes the weight of asthma disease on our society, having directed the National Institute of Health to create evidence-based guidelines for asthma care. Additionally, the DHHS continues to recognize asthma as a key element of the Healthy People 2020 initiative with several specific health objectives related directly to inpatient management. Due to the chronic nature of this disease, pediatric hospitalists should not only treat acute exacerbations resulting in status asthmaticus, but also create or reaffirm long-term management plans.
Knowledge
Pediatric hospitalists should be able to:
- Discuss the pathophysiology of asthma addressing both bronchoconstrictive and inflammatory components, and state how each impact pharmacologic treatment choices.
- Compare and contrast the pathophysiology of asthma with other common small airway illnesses in children, such as bronchiolitis, viral pneumonia with bronchospasm, or chronic lung disease.
- Describe disparities in asthma prevalence by sex, race, socioeconomic level, and geographic location.
- Discuss the role psychosocial factors (such as housing, parental mental health, financial status, lack of health insurance, and others) play in the risk for exposure to allergens, non-compliance to medical regimens, and access to health care.
- List the differential diagnosis of wheezing for various age groups and delineate the defining features leading to a diagnosis of asthma.
- Define asthma groups by symptom severity and frequency based on current classification guidelines.
- Discuss the impact of risk factors, exacerbating factors, and chronic comorbidities on morbidity, treatment, and prognosis.
- List common asthma triggers and explain the importance of trigger avoidance and environmental controls in minimizing the frequency and severity of asthma exacerbations.
- State the basic pharmacology, safety profile, and potential adverse effects of commonly used medications, including bronchodilators, leukotriene modifiers, inhaled or systemic corticosteroids, and magnesium sulfate
- Compare and contrast indications for the use of high dose bronchodilator therapy via multiple meter dose inhaler or continuous nebulized albuterol.
- Describe the different formulations of systemic corticosteroids commonly used for treatment of acute asthma exacerbation and the indications for each.
- Describe the utility of alternate therapies such as magnesium sulfate for acute refractory asthma.
- Cite the common complications of asthma or asthma treatment, including pneumothorax, atelectasis, lobar collapse, respiratory failure, poor cardiac output, dysrhythmias, and others.
- Describe the utility of using asthma management plans to both monitor and treat asthma via early symptom recognition, pulmonary function testing (spirometry and/or peak flow), and proper use of controller and reliever medications.
- Discuss the goals of asthma management, including the maintenance of normal activity levels (including physical activity, uninterrupted sleep, and school attendance) and pulmonary function; the prevention of chronic symptoms, recurrent exacerbations, and hospitalizations; and the provision of optimal pharmacotherapy, while minimizing adverse events.
- List specific indications for referral to an asthma subspecialist.
Skills
Pediatric hospitalists should be able to:
- Diagnose and correctly classify asthma by efficiently performing an accurate history and physical examination.
- Assess clinical findings to determine the need for hospitalization and the appropriate level of care.
- Direct an evidence-based treatment plan for status asthmaticus.
- Identify and respond to side effects associated with asthma medications.
- Order and interpret objective measures of pulmonary function, including peak flow monitoring and spirometry.
- Order and interpret results of basic diagnostic tools, such as chest radiograph, blood gas, and others as indicated.
- Order appropriate monitoring and correctly interpret monitor data.
- Provide supplemental oxygen therapy and advanced airway management as necessary.
- Recognize signs and symptoms of serious complications of asthma, including pneumothorax or impending respiratory failure.
- Facilitate an effective transfer to a tertiary care center or intensive care setting when appropriate.
- Assess disease severity and modify the daily medication regimen based upon accurate assessment of changes in disease state, both for inpatient management and transition to home.
- Assess psychosocial factors that may impact care plans and provide appropriate interventions, including support, education, and referral to available resources.
- Initiate asthma education for patients and the family/caregivers as soon after admission as possible, as appropriate for the clinical context.
- Create a discharge plan that can be expediently activated when appropriate.
- Coordinate care with the primary care provider with a plan inclusive of discharge medications, home instructions, and follow-up plans.
- Complete a written asthma action plan and use it to educate patients and the family/caregivers on trigger avoidance, medication adherence, and disease control.
Attitudes
Pediatric hospitalists should be able to:
- Reinforce the role and responsibility of patients and the family/caregivers regarding self-care, recognition of symptoms, and disease management.
- Realize responsibility for effective communication with patients, the family/caregivers, and healthcare providers regarding care plans.
- Engage in a multi-disciplinary approach to the prevention, diagnosis, and treatment of asthma, involving when appropriate, social workers or case managers, respiratory therapists, and subspecialists.
- Collaborate with primary care providers and subspecialists to ensure coordinated longitudinal care for children with asthma.
Systems Organization and Improvement
In order to improve efficiency and quality within their organizations, pediatric hospitalists should:
- Lead, coordinate, or participate in local and national initiatives to further the development and implementation of evidence-based clinical guidelines to promote effective resource utilization and improve quality of care for hospitalized children with asthma.
- Work with hospital administrators to implement and utilize performance feedback and quality improvement measures to assess outcomes of instituted guidelines for the management of inpatient asthma.
- Collaborate with primary care providers, subspecialists, social workers, and case managers to ensure a smooth transition to the outpatient setting, and to minimize the need for readmission.
Introduction
Asthma is one of the most common, non-communicable, chronic childhood diseases. It is a leading cause of healthcare utilization resulting in a significant number of primary care visits, emergency room visits, and hospitalizations. It has direct impact on patient quality of life with a heavy financial burden to individuals and society. The prevalence of asthma continues to rise and is not equally distributed throughout the population, differing by sex, race, socioeconomic level, and geographic location. The Department of Health and Human Services (DHHS) recognizes the weight of asthma disease on our society, having directed the National Institute of Health to create evidence-based guidelines for asthma care. Additionally, the DHHS continues to recognize asthma as a key element of the Healthy People 2020 initiative with several specific health objectives related directly to inpatient management. Due to the chronic nature of this disease, pediatric hospitalists should not only treat acute exacerbations resulting in status asthmaticus, but also create or reaffirm long-term management plans.
Knowledge
Pediatric hospitalists should be able to:
- Discuss the pathophysiology of asthma addressing both bronchoconstrictive and inflammatory components, and state how each impact pharmacologic treatment choices.
- Compare and contrast the pathophysiology of asthma with other common small airway illnesses in children, such as bronchiolitis, viral pneumonia with bronchospasm, or chronic lung disease.
- Describe disparities in asthma prevalence by sex, race, socioeconomic level, and geographic location.
- Discuss the role psychosocial factors (such as housing, parental mental health, financial status, lack of health insurance, and others) play in the risk for exposure to allergens, non-compliance to medical regimens, and access to health care.
- List the differential diagnosis of wheezing for various age groups and delineate the defining features leading to a diagnosis of asthma.
- Define asthma groups by symptom severity and frequency based on current classification guidelines.
- Discuss the impact of risk factors, exacerbating factors, and chronic comorbidities on morbidity, treatment, and prognosis.
- List common asthma triggers and explain the importance of trigger avoidance and environmental controls in minimizing the frequency and severity of asthma exacerbations.
- State the basic pharmacology, safety profile, and potential adverse effects of commonly used medications, including bronchodilators, leukotriene modifiers, inhaled or systemic corticosteroids, and magnesium sulfate
- Compare and contrast indications for the use of high dose bronchodilator therapy via multiple meter dose inhaler or continuous nebulized albuterol.
- Describe the different formulations of systemic corticosteroids commonly used for treatment of acute asthma exacerbation and the indications for each.
- Describe the utility of alternate therapies such as magnesium sulfate for acute refractory asthma.
- Cite the common complications of asthma or asthma treatment, including pneumothorax, atelectasis, lobar collapse, respiratory failure, poor cardiac output, dysrhythmias, and others.
- Describe the utility of using asthma management plans to both monitor and treat asthma via early symptom recognition, pulmonary function testing (spirometry and/or peak flow), and proper use of controller and reliever medications.
- Discuss the goals of asthma management, including the maintenance of normal activity levels (including physical activity, uninterrupted sleep, and school attendance) and pulmonary function; the prevention of chronic symptoms, recurrent exacerbations, and hospitalizations; and the provision of optimal pharmacotherapy, while minimizing adverse events.
- List specific indications for referral to an asthma subspecialist.
Skills
Pediatric hospitalists should be able to:
- Diagnose and correctly classify asthma by efficiently performing an accurate history and physical examination.
- Assess clinical findings to determine the need for hospitalization and the appropriate level of care.
- Direct an evidence-based treatment plan for status asthmaticus.
- Identify and respond to side effects associated with asthma medications.
- Order and interpret objective measures of pulmonary function, including peak flow monitoring and spirometry.
- Order and interpret results of basic diagnostic tools, such as chest radiograph, blood gas, and others as indicated.
- Order appropriate monitoring and correctly interpret monitor data.
- Provide supplemental oxygen therapy and advanced airway management as necessary.
- Recognize signs and symptoms of serious complications of asthma, including pneumothorax or impending respiratory failure.
- Facilitate an effective transfer to a tertiary care center or intensive care setting when appropriate.
- Assess disease severity and modify the daily medication regimen based upon accurate assessment of changes in disease state, both for inpatient management and transition to home.
- Assess psychosocial factors that may impact care plans and provide appropriate interventions, including support, education, and referral to available resources.
- Initiate asthma education for patients and the family/caregivers as soon after admission as possible, as appropriate for the clinical context.
- Create a discharge plan that can be expediently activated when appropriate.
- Coordinate care with the primary care provider with a plan inclusive of discharge medications, home instructions, and follow-up plans.
- Complete a written asthma action plan and use it to educate patients and the family/caregivers on trigger avoidance, medication adherence, and disease control.
Attitudes
Pediatric hospitalists should be able to:
- Reinforce the role and responsibility of patients and the family/caregivers regarding self-care, recognition of symptoms, and disease management.
- Realize responsibility for effective communication with patients, the family/caregivers, and healthcare providers regarding care plans.
- Engage in a multi-disciplinary approach to the prevention, diagnosis, and treatment of asthma, involving when appropriate, social workers or case managers, respiratory therapists, and subspecialists.
- Collaborate with primary care providers and subspecialists to ensure coordinated longitudinal care for children with asthma.
Systems Organization and Improvement
In order to improve efficiency and quality within their organizations, pediatric hospitalists should:
- Lead, coordinate, or participate in local and national initiatives to further the development and implementation of evidence-based clinical guidelines to promote effective resource utilization and improve quality of care for hospitalized children with asthma.
- Work with hospital administrators to implement and utilize performance feedback and quality improvement measures to assess outcomes of instituted guidelines for the management of inpatient asthma.
- Collaborate with primary care providers, subspecialists, social workers, and case managers to ensure a smooth transition to the outpatient setting, and to minimize the need for readmission.
1. U.S. Department of Health and Human Services, National Institutes of Health. Expert Panel Report 3: Guidelines for the Diagnosis and Management of Asthma (EPR-3). 2007 Edition. http://www.nhlbi.nih.gov/health-pro/guidelines/current/asthma-guidelines. Accessed August 22, 2019.
2. Jones BP, Fleming GM, Otillio JK, Asokan I, Arnold DH. Pediatric acute asthma exacerbations: Evaluation and management from emergency department to intensive care unit. J Asthma. 2016;53(6):607-617. https://doi.org/10.3109/02770903.2015.1067323.
3. Saglani S, Fleming L, Sonnappa S, and Bush A. Advances in the aetiology, management, and prevention of acute asthma attacks in children. Lancet Child Adol Health. 2019;3(5):354-364. https://doi.org/10.1016/S2352-4642(19)30025-2.
1. U.S. Department of Health and Human Services, National Institutes of Health. Expert Panel Report 3: Guidelines for the Diagnosis and Management of Asthma (EPR-3). 2007 Edition. http://www.nhlbi.nih.gov/health-pro/guidelines/current/asthma-guidelines. Accessed August 22, 2019.
2. Jones BP, Fleming GM, Otillio JK, Asokan I, Arnold DH. Pediatric acute asthma exacerbations: Evaluation and management from emergency department to intensive care unit. J Asthma. 2016;53(6):607-617. https://doi.org/10.3109/02770903.2015.1067323.
3. Saglani S, Fleming L, Sonnappa S, and Bush A. Advances in the aetiology, management, and prevention of acute asthma attacks in children. Lancet Child Adol Health. 2019;3(5):354-364. https://doi.org/10.1016/S2352-4642(19)30025-2.
1.04 Common Clinical Diagnoses and Conditions: Altered Mental Status
Introduction
Altered mental status (AMS) is a descriptive term that encompasses a wide spectrum of signs and symptoms, ranging from vague complaints of atypical behavior and irritability, to more specific concerns related to both hyperactive states (such as agitation) and hypoactive states (such as lethargy, depressed levels of responsiveness, and loss of consciousness). AMS may be particularly difficult to recognize in very young children and children with medical complexity. Pediatric hospitalists frequently encounter children with AMS, either as a primary cause for admission or a secondary finding during hospitalization, and therefore they must be knowledgeable about the differential diagnosis and various organ system manifestations that may be involved. Pediatric hospitalists must be able to accurately recognize early signs of AMS, triage acuity, and provide prompt stabilization, which is critical to effective management of patients with this condition.
Knowledge
Pediatric Hospitalists should be able to:
- Compare and contrast the different presentations of AMS, and describe the differential diagnosis associated with each for varying chronological or developmental ages.
- Identify the elements of the Glasgow Coma Scale and discuss the implications of the score or a change in score on management of a child with AMS.
- Discuss the features of the medical history and physical examination that prompt specific diagnostic evaluation, including signs and symptoms that warrant urgent management.
- Compare and contrast different features of toxidromes that may present with AMS.
- Discuss approaches to stabilization of a child with AMS, including evaluation of airway, breathing, circulation, disability, exposure, and intracranial perfusion.
- Define the indications to activate a rapid response, code blue, or other local emergency system for children with AMS.
- Explain indications for hospitalization of children with AMS.
- Summarize the initial approach to management of common conditions presenting with AMS, including but not limited to: seizures, increased intracranial pressure, intracranial hemorrhage, infectious or inflammatory encephalitis, sepsis, shock, hypoglycemia, diabetic ketoacidosis, renal or liver failure, neoplastic syndromes, suspected toxic ingestion, medication overdose, and adverse drug reaction.
- Discuss specific considerations for children with medical complexity presenting with AMS, including those with intellectual disability, impaired communication, epilepsy, dystonia, ventricular shunts, ventilator dependence, enteral feeding tubes, and multiple medications.
- Discuss the mechanisms of action of common medications used for delirium or agitation.
- Discuss the mechanisms of action of medications used for increased intracranial pressure (such as mannitol, 3% hypertonic saline, and others).
- List medications commonly used in the inpatient setting that may cause AMS as a side effect of use or withdrawal of use, such as seizure medications, opioids, benzodiazepines, anti-cholinergic medications, barbiturates, cannabinoids, and others.
- Explain the indications for chemical versus physical restraints, one-to-one supervision, and involvement of hospital security to ensure safety of the patient, family, and staff.
- Describe indications for urgent subspecialist consultation for children with AMS (such as toxicology, rheumatology, neurology, neurosurgery, and others).
- Discuss reasons for transfer to higher level of care, within the institution or elsewhere if pediatric-specific or psychiatric services are not available at the local facility.
- Describe the reasons for ancillary service involvement (such as physical, occupational, speech, feeding, behavioral therapies, and others) and durable medical equipment procurement for children with AMS.
- List criteria for inpatient rehabilitation.
- Discuss indications for involvement of social work, child protective services, or law enforcement for children with AMS.
Skills
Pediatric Hospitalists should be able to:
- Elicit a thorough medical history, attending to a detailed care provider history, past medical history, exposures, medications, and medications in the home.
- Perform a physical exam to elicit signs of AMS, including evaluation of airway, breathing, circulation, psychiatric status, and the central and autonomic nervous system.
- Assign an accurate Glasgow Coma Scale score.
- Identify children with potentially reversible, life-threatening conditions, and promptly provide stabilizing measures, activating code or rapid response teams as indicated.
- Review medication list and note any potentially relevant interactions or adverse effects.
- Direct an appropriate, cost-effective evaluation to identify the cause of AMS and correctly interpret results, including performance of a lumbar puncture as indicated.
- Perform careful reassessments (such as serial neurological exams, Glasgow Coma Scale scoring, and others), identifying indications for adjustment to the plan of care, frequency of monitoring, and type of monitoring indicated.
- Identify and manage children who present with altered mental status secondary to common conditions, such as seizures, increased intracranial pressure, intracranial hemorrhage, infectious or inflammatory encephalitis, sepsis, shock, hypoglycemia, diabetic ketoacidosis, renal or liver failure, neoplastic syndromes, suspected toxic ingestion, medication overdose, and adverse drug reaction.
- Engage consultants, including neurologists, neurosurgeons, neuroradiologists, toxicologists, psychiatrists, and psychologists efficiently and appropriately.
- Coordinate care and communicate effectively with caregivers, primary care providers, and consultants about the mental status at the time of discharge and the transition plan, referring to ancillary or rehabilitation services as appropriate.
Attitudes
Pediatric Hospitalists should be able to:
- Realize responsibility for reporting of iatrogenic etiologies as appropriate.
- Acknowledge the need for effective communication with subspecialty providers, primary care providers, and the patients and the family/caregivers to ensure ongoing support and coordinated care.
- Realize responsibility for effective and compassionate communication with patients/caregivers regarding findings, prognosis, and treatments, accounting for the stresses of hospitalization.
- Collaborate with social work, child protective services, and law enforcement when indicated.
Systems Organization and Improvement
In order to improve efficiency and quality within their organizations, pediatric hospitalists should:
- Work with hospital administration and staff to develop, implement, and assess outcomes of intervention strategies for hospitalized patients with deterioration of mental status to prevent adverse outcomes (such as rapid response, code blue, stroke teams, and others).
- Coordinate educational programs for front-line providers to promote early recognition of AMS.
- Lead, coordinate, or participate in institutional efforts to report and reduce cases of AMS due to iatrogenic causes or adverse effects of medications.
1. Lehman RK, Mink J. Altered mental status. Clin Pediatr Emerg Med. 2008; 9:68-75.
2. Avner JR. Altered states of consciousness. Pediatr Rev. 2006; 27:331-338. https://doi.org/10.1542/pir.27-9-331.
3. Malas N, Brahmbhatt K, McDermott C, Smith A. Ortiz-Aguayo R, Turkel S. Pediatric delirium: Evaluation, management, and special considerations. Curr Psychiatry Rep. 2017;19(9):65. https://doi.org/10.1007/s11920-017-0817-3.
1. Lehman RK, Mink J. Altered mental status. Clin Pediatr Emerg Med. 2008; 9:68-75.
2. Avner JR. Altered states of consciousness. Pediatr Rev. 2006; 27:331-338. https://doi.org/10.1542/pir.27-9-331.
3. Malas N, Brahmbhatt K, McDermott C, Smith A. Ortiz-Aguayo R, Turkel S. Pediatric delirium: Evaluation, management, and special considerations. Curr Psychiatry Rep. 2017;19(9):65. https://doi.org/10.1007/s11920-017-0817-3.
Introduction
Altered mental status (AMS) is a descriptive term that encompasses a wide spectrum of signs and symptoms, ranging from vague complaints of atypical behavior and irritability, to more specific concerns related to both hyperactive states (such as agitation) and hypoactive states (such as lethargy, depressed levels of responsiveness, and loss of consciousness). AMS may be particularly difficult to recognize in very young children and children with medical complexity. Pediatric hospitalists frequently encounter children with AMS, either as a primary cause for admission or a secondary finding during hospitalization, and therefore they must be knowledgeable about the differential diagnosis and various organ system manifestations that may be involved. Pediatric hospitalists must be able to accurately recognize early signs of AMS, triage acuity, and provide prompt stabilization, which is critical to effective management of patients with this condition.
Knowledge
Pediatric Hospitalists should be able to:
- Compare and contrast the different presentations of AMS, and describe the differential diagnosis associated with each for varying chronological or developmental ages.
- Identify the elements of the Glasgow Coma Scale and discuss the implications of the score or a change in score on management of a child with AMS.
- Discuss the features of the medical history and physical examination that prompt specific diagnostic evaluation, including signs and symptoms that warrant urgent management.
- Compare and contrast different features of toxidromes that may present with AMS.
- Discuss approaches to stabilization of a child with AMS, including evaluation of airway, breathing, circulation, disability, exposure, and intracranial perfusion.
- Define the indications to activate a rapid response, code blue, or other local emergency system for children with AMS.
- Explain indications for hospitalization of children with AMS.
- Summarize the initial approach to management of common conditions presenting with AMS, including but not limited to: seizures, increased intracranial pressure, intracranial hemorrhage, infectious or inflammatory encephalitis, sepsis, shock, hypoglycemia, diabetic ketoacidosis, renal or liver failure, neoplastic syndromes, suspected toxic ingestion, medication overdose, and adverse drug reaction.
- Discuss specific considerations for children with medical complexity presenting with AMS, including those with intellectual disability, impaired communication, epilepsy, dystonia, ventricular shunts, ventilator dependence, enteral feeding tubes, and multiple medications.
- Discuss the mechanisms of action of common medications used for delirium or agitation.
- Discuss the mechanisms of action of medications used for increased intracranial pressure (such as mannitol, 3% hypertonic saline, and others).
- List medications commonly used in the inpatient setting that may cause AMS as a side effect of use or withdrawal of use, such as seizure medications, opioids, benzodiazepines, anti-cholinergic medications, barbiturates, cannabinoids, and others.
- Explain the indications for chemical versus physical restraints, one-to-one supervision, and involvement of hospital security to ensure safety of the patient, family, and staff.
- Describe indications for urgent subspecialist consultation for children with AMS (such as toxicology, rheumatology, neurology, neurosurgery, and others).
- Discuss reasons for transfer to higher level of care, within the institution or elsewhere if pediatric-specific or psychiatric services are not available at the local facility.
- Describe the reasons for ancillary service involvement (such as physical, occupational, speech, feeding, behavioral therapies, and others) and durable medical equipment procurement for children with AMS.
- List criteria for inpatient rehabilitation.
- Discuss indications for involvement of social work, child protective services, or law enforcement for children with AMS.
Skills
Pediatric Hospitalists should be able to:
- Elicit a thorough medical history, attending to a detailed care provider history, past medical history, exposures, medications, and medications in the home.
- Perform a physical exam to elicit signs of AMS, including evaluation of airway, breathing, circulation, psychiatric status, and the central and autonomic nervous system.
- Assign an accurate Glasgow Coma Scale score.
- Identify children with potentially reversible, life-threatening conditions, and promptly provide stabilizing measures, activating code or rapid response teams as indicated.
- Review medication list and note any potentially relevant interactions or adverse effects.
- Direct an appropriate, cost-effective evaluation to identify the cause of AMS and correctly interpret results, including performance of a lumbar puncture as indicated.
- Perform careful reassessments (such as serial neurological exams, Glasgow Coma Scale scoring, and others), identifying indications for adjustment to the plan of care, frequency of monitoring, and type of monitoring indicated.
- Identify and manage children who present with altered mental status secondary to common conditions, such as seizures, increased intracranial pressure, intracranial hemorrhage, infectious or inflammatory encephalitis, sepsis, shock, hypoglycemia, diabetic ketoacidosis, renal or liver failure, neoplastic syndromes, suspected toxic ingestion, medication overdose, and adverse drug reaction.
- Engage consultants, including neurologists, neurosurgeons, neuroradiologists, toxicologists, psychiatrists, and psychologists efficiently and appropriately.
- Coordinate care and communicate effectively with caregivers, primary care providers, and consultants about the mental status at the time of discharge and the transition plan, referring to ancillary or rehabilitation services as appropriate.
Attitudes
Pediatric Hospitalists should be able to:
- Realize responsibility for reporting of iatrogenic etiologies as appropriate.
- Acknowledge the need for effective communication with subspecialty providers, primary care providers, and the patients and the family/caregivers to ensure ongoing support and coordinated care.
- Realize responsibility for effective and compassionate communication with patients/caregivers regarding findings, prognosis, and treatments, accounting for the stresses of hospitalization.
- Collaborate with social work, child protective services, and law enforcement when indicated.
Systems Organization and Improvement
In order to improve efficiency and quality within their organizations, pediatric hospitalists should:
- Work with hospital administration and staff to develop, implement, and assess outcomes of intervention strategies for hospitalized patients with deterioration of mental status to prevent adverse outcomes (such as rapid response, code blue, stroke teams, and others).
- Coordinate educational programs for front-line providers to promote early recognition of AMS.
- Lead, coordinate, or participate in institutional efforts to report and reduce cases of AMS due to iatrogenic causes or adverse effects of medications.
1. Lehman RK, Mink J. Altered mental status. Clin Pediatr Emerg Med. 2008; 9:68-75.
2. Avner JR. Altered states of consciousness. Pediatr Rev. 2006; 27:331-338. https://doi.org/10.1542/pir.27-9-331.
3. Malas N, Brahmbhatt K, McDermott C, Smith A. Ortiz-Aguayo R, Turkel S. Pediatric delirium: Evaluation, management, and special considerations. Curr Psychiatry Rep. 2017;19(9):65. https://doi.org/10.1007/s11920-017-0817-3.
Introduction
Altered mental status (AMS) is a descriptive term that encompasses a wide spectrum of signs and symptoms, ranging from vague complaints of atypical behavior and irritability, to more specific concerns related to both hyperactive states (such as agitation) and hypoactive states (such as lethargy, depressed levels of responsiveness, and loss of consciousness). AMS may be particularly difficult to recognize in very young children and children with medical complexity. Pediatric hospitalists frequently encounter children with AMS, either as a primary cause for admission or a secondary finding during hospitalization, and therefore they must be knowledgeable about the differential diagnosis and various organ system manifestations that may be involved. Pediatric hospitalists must be able to accurately recognize early signs of AMS, triage acuity, and provide prompt stabilization, which is critical to effective management of patients with this condition.
Knowledge
Pediatric Hospitalists should be able to:
- Compare and contrast the different presentations of AMS, and describe the differential diagnosis associated with each for varying chronological or developmental ages.
- Identify the elements of the Glasgow Coma Scale and discuss the implications of the score or a change in score on management of a child with AMS.
- Discuss the features of the medical history and physical examination that prompt specific diagnostic evaluation, including signs and symptoms that warrant urgent management.
- Compare and contrast different features of toxidromes that may present with AMS.
- Discuss approaches to stabilization of a child with AMS, including evaluation of airway, breathing, circulation, disability, exposure, and intracranial perfusion.
- Define the indications to activate a rapid response, code blue, or other local emergency system for children with AMS.
- Explain indications for hospitalization of children with AMS.
- Summarize the initial approach to management of common conditions presenting with AMS, including but not limited to: seizures, increased intracranial pressure, intracranial hemorrhage, infectious or inflammatory encephalitis, sepsis, shock, hypoglycemia, diabetic ketoacidosis, renal or liver failure, neoplastic syndromes, suspected toxic ingestion, medication overdose, and adverse drug reaction.
- Discuss specific considerations for children with medical complexity presenting with AMS, including those with intellectual disability, impaired communication, epilepsy, dystonia, ventricular shunts, ventilator dependence, enteral feeding tubes, and multiple medications.
- Discuss the mechanisms of action of common medications used for delirium or agitation.
- Discuss the mechanisms of action of medications used for increased intracranial pressure (such as mannitol, 3% hypertonic saline, and others).
- List medications commonly used in the inpatient setting that may cause AMS as a side effect of use or withdrawal of use, such as seizure medications, opioids, benzodiazepines, anti-cholinergic medications, barbiturates, cannabinoids, and others.
- Explain the indications for chemical versus physical restraints, one-to-one supervision, and involvement of hospital security to ensure safety of the patient, family, and staff.
- Describe indications for urgent subspecialist consultation for children with AMS (such as toxicology, rheumatology, neurology, neurosurgery, and others).
- Discuss reasons for transfer to higher level of care, within the institution or elsewhere if pediatric-specific or psychiatric services are not available at the local facility.
- Describe the reasons for ancillary service involvement (such as physical, occupational, speech, feeding, behavioral therapies, and others) and durable medical equipment procurement for children with AMS.
- List criteria for inpatient rehabilitation.
- Discuss indications for involvement of social work, child protective services, or law enforcement for children with AMS.
Skills
Pediatric Hospitalists should be able to:
- Elicit a thorough medical history, attending to a detailed care provider history, past medical history, exposures, medications, and medications in the home.
- Perform a physical exam to elicit signs of AMS, including evaluation of airway, breathing, circulation, psychiatric status, and the central and autonomic nervous system.
- Assign an accurate Glasgow Coma Scale score.
- Identify children with potentially reversible, life-threatening conditions, and promptly provide stabilizing measures, activating code or rapid response teams as indicated.
- Review medication list and note any potentially relevant interactions or adverse effects.
- Direct an appropriate, cost-effective evaluation to identify the cause of AMS and correctly interpret results, including performance of a lumbar puncture as indicated.
- Perform careful reassessments (such as serial neurological exams, Glasgow Coma Scale scoring, and others), identifying indications for adjustment to the plan of care, frequency of monitoring, and type of monitoring indicated.
- Identify and manage children who present with altered mental status secondary to common conditions, such as seizures, increased intracranial pressure, intracranial hemorrhage, infectious or inflammatory encephalitis, sepsis, shock, hypoglycemia, diabetic ketoacidosis, renal or liver failure, neoplastic syndromes, suspected toxic ingestion, medication overdose, and adverse drug reaction.
- Engage consultants, including neurologists, neurosurgeons, neuroradiologists, toxicologists, psychiatrists, and psychologists efficiently and appropriately.
- Coordinate care and communicate effectively with caregivers, primary care providers, and consultants about the mental status at the time of discharge and the transition plan, referring to ancillary or rehabilitation services as appropriate.
Attitudes
Pediatric Hospitalists should be able to:
- Realize responsibility for reporting of iatrogenic etiologies as appropriate.
- Acknowledge the need for effective communication with subspecialty providers, primary care providers, and the patients and the family/caregivers to ensure ongoing support and coordinated care.
- Realize responsibility for effective and compassionate communication with patients/caregivers regarding findings, prognosis, and treatments, accounting for the stresses of hospitalization.
- Collaborate with social work, child protective services, and law enforcement when indicated.
Systems Organization and Improvement
In order to improve efficiency and quality within their organizations, pediatric hospitalists should:
- Work with hospital administration and staff to develop, implement, and assess outcomes of intervention strategies for hospitalized patients with deterioration of mental status to prevent adverse outcomes (such as rapid response, code blue, stroke teams, and others).
- Coordinate educational programs for front-line providers to promote early recognition of AMS.
- Lead, coordinate, or participate in institutional efforts to report and reduce cases of AMS due to iatrogenic causes or adverse effects of medications.
1. Lehman RK, Mink J. Altered mental status. Clin Pediatr Emerg Med. 2008; 9:68-75.
2. Avner JR. Altered states of consciousness. Pediatr Rev. 2006; 27:331-338. https://doi.org/10.1542/pir.27-9-331.
3. Malas N, Brahmbhatt K, McDermott C, Smith A. Ortiz-Aguayo R, Turkel S. Pediatric delirium: Evaluation, management, and special considerations. Curr Psychiatry Rep. 2017;19(9):65. https://doi.org/10.1007/s11920-017-0817-3.
1. Lehman RK, Mink J. Altered mental status. Clin Pediatr Emerg Med. 2008; 9:68-75.
2. Avner JR. Altered states of consciousness. Pediatr Rev. 2006; 27:331-338. https://doi.org/10.1542/pir.27-9-331.
3. Malas N, Brahmbhatt K, McDermott C, Smith A. Ortiz-Aguayo R, Turkel S. Pediatric delirium: Evaluation, management, and special considerations. Curr Psychiatry Rep. 2017;19(9):65. https://doi.org/10.1007/s11920-017-0817-3.
1. Lehman RK, Mink J. Altered mental status. Clin Pediatr Emerg Med. 2008; 9:68-75.
2. Avner JR. Altered states of consciousness. Pediatr Rev. 2006; 27:331-338. https://doi.org/10.1542/pir.27-9-331.
3. Malas N, Brahmbhatt K, McDermott C, Smith A. Ortiz-Aguayo R, Turkel S. Pediatric delirium: Evaluation, management, and special considerations. Curr Psychiatry Rep. 2017;19(9):65. https://doi.org/10.1007/s11920-017-0817-3.
1.03 Common Clinical Diagnoses and Conditions: Acute Respiratory Failure
Introduction
Respiratory failure is defined by inadequate gas exchange by the respiratory system that results in ineffective alveolar ventilation and/or oxygenation. Acute respiratory failure is more common in children than adults and is the primary cause of cardiopulmonary arrest in children. The differential diagnosis for acute respiratory failure in children is extensive, as failure may stem from any portion of the respiratory system or be a consequence of systemic disease. Pediatric hospitalists frequently encounter children with conditions affecting the respiratory system and should be able to anticipate, identify, and treat acute respiratory distress and acute respiratory failure in children, including those with chronic respiratory conditions and other comorbidities.
Knowledge
Pediatric hospitalists should be able to:
- Describe the structure and function respiratory system components, including upper and lower airways, muscles of respiration, and central and peripheral regulation systems.
- Explain developmental differences that contribute to acute respiratory failure in infants and young children, including upper airway size, lower airway growth and development, diaphragmatic muscle reserve, chest wall compliance, and respiratory regulatory center maturity.
- Discuss the basic principles of respiratory physiology, including the alveolar gas equation, minute ventilation, and alveolar-arterial gradient.
- Summarize the five causes of hypoxemia: ventilation-perfusion mismatch, hypoventilation, right to left shunt, diffusion impairment, and low inspired oxygen.
- Construct an age-based differential diagnosis for acute respiratory distress in children.
- List causes of poor respiratory muscle function, attending to age, neuromuscular disorders, central nervous system dysfunction, nerve injury, and others.
- Discuss comorbidities that place children at higher risk for acute respiratory failure.
- Summarize evaluation, monitoring, and treatment options for patients with worsening respiratory status, including mental status assessment, blood gas analysis, medications, and respiratory support.
- Describe the signs and symptoms of impending acute respiratory failure, including criteria for transfer to a higher level of care.
- Discuss the advantages and disadvantages of different supplemental oxygen delivery devices for children with and without medical complexity, such as low flow and heated high-flow nasal cannula, simple mask, partial rebreather or non-rebreather, and tracheostomy collar or mask.
- Summarize the modalities commonly available to support the airway and adequate gas exchange in children with worsening respiratory distress, including nasopharyngeal or oropharyngeal airways, bag-valve-mask ventilation, bi-level positive airway pressure, continuous positive airway pressure, endotracheal tube, and laryngeal-mask-airway intubation.
- Describe criteria for, risks of, and complications due to endotracheal or laryngeal-mask-airway intubation, including strategies to reduce these risks.
- Compare and contrast optimal treatment strategies for acute respiratory failure in children with common acute respiratory conditions, including asthma, bronchiolitis, croup, and pneumonia.
Skills
Pediatric hospitalists should be able to:
- Perform and teach other health care providers to perform a thorough respiratory assessment of a child with acute respiratory distress.
- Identify early warning signs of acute respiratory distress and institute corrective actions and therapies to avert further deterioration.
- Identify patients with comorbidities and other risk factors for progression to acute respiratory failure.
- Order appropriate monitoring and relevant testing (such as radiographs and blood gases) and correctly interpret their results.
- Diagnose and initiate medical management for systemic causes of acute respiratory failure.
- Identify signs and symptoms of impending acute respiratory failure and activate local emergency response teams and/or transfer patients to an appropriate site with critical care services in a safe and efficient manner.
- Initiate oxygen supplementation via oxygen delivery devices and escalate as required to manage hypoxia and/or acute respiratory distress.
- Stabilize the airway, using non-invasive airway management techniques independently and invasive airway management in collaboration with other services.
- Demonstrate proficiency in basic management of patients with chronic respiratory support needs.
- Identify patients requiring subspecialty care and obtain timely consults.
Attitudes
Pediatric hospitalists should be able to:
- Acknowledge the importance of collaboration with patients, the family/caregivers, hospital staff, and subspecialists to ensure family-centered, coordinated hospital care for children with conditions at risk for acute respiratory failure.
- Realize the value of providing consultation for healthcare providers in community settings to ensure transport of patients to higher acuity settings as needed.
Systems Organization and Improvement
In order to improve efficiency and quality within their organizations, pediatric hospitalists should:
- Lead, coordinate, or participate in educational programs for the family/caregivers, hospital staff, and other healthcare providers regarding recognition of signs and symptoms of acute respiratory distress in children, particularly those at higher risk for acute respiratory failure.
- Work with hospital administration, hospital staff, subspecialists, and others to develop, implement, and assess outcomes of intervention strategies such as rapid response teams and early warning scores for hospitalized patients with deterioration in respiratory status in order to prevent adverse outcomes.
- Work with hospital administration, hospital staff, pharmacy, and others to ensure availability of medications and appropriately sized equipment for use in the management of acute respiratory failure in children.
1. Samson RA, Schexnayder SM, Hazinski MF, et al. Part 3 Systematic approach to the seriously ill or injured child, Part 6 Recognition of Respiratory Distress and Failure, and Part 7 Management of Respiratory Distress and Failure. In: Pediatric Advanced Life Support: Provider Manual. Dallas, TX: American Heart Association; 2016;29-68; 113-170.
2. Hammer J. Acute respiratory failure in children. Paediatr Respir Rev. 2013; 14:64-69. https://doi.org/10.1016/j.prrv.2013.02.001.
Introduction
Respiratory failure is defined by inadequate gas exchange by the respiratory system that results in ineffective alveolar ventilation and/or oxygenation. Acute respiratory failure is more common in children than adults and is the primary cause of cardiopulmonary arrest in children. The differential diagnosis for acute respiratory failure in children is extensive, as failure may stem from any portion of the respiratory system or be a consequence of systemic disease. Pediatric hospitalists frequently encounter children with conditions affecting the respiratory system and should be able to anticipate, identify, and treat acute respiratory distress and acute respiratory failure in children, including those with chronic respiratory conditions and other comorbidities.
Knowledge
Pediatric hospitalists should be able to:
- Describe the structure and function respiratory system components, including upper and lower airways, muscles of respiration, and central and peripheral regulation systems.
- Explain developmental differences that contribute to acute respiratory failure in infants and young children, including upper airway size, lower airway growth and development, diaphragmatic muscle reserve, chest wall compliance, and respiratory regulatory center maturity.
- Discuss the basic principles of respiratory physiology, including the alveolar gas equation, minute ventilation, and alveolar-arterial gradient.
- Summarize the five causes of hypoxemia: ventilation-perfusion mismatch, hypoventilation, right to left shunt, diffusion impairment, and low inspired oxygen.
- Construct an age-based differential diagnosis for acute respiratory distress in children.
- List causes of poor respiratory muscle function, attending to age, neuromuscular disorders, central nervous system dysfunction, nerve injury, and others.
- Discuss comorbidities that place children at higher risk for acute respiratory failure.
- Summarize evaluation, monitoring, and treatment options for patients with worsening respiratory status, including mental status assessment, blood gas analysis, medications, and respiratory support.
- Describe the signs and symptoms of impending acute respiratory failure, including criteria for transfer to a higher level of care.
- Discuss the advantages and disadvantages of different supplemental oxygen delivery devices for children with and without medical complexity, such as low flow and heated high-flow nasal cannula, simple mask, partial rebreather or non-rebreather, and tracheostomy collar or mask.
- Summarize the modalities commonly available to support the airway and adequate gas exchange in children with worsening respiratory distress, including nasopharyngeal or oropharyngeal airways, bag-valve-mask ventilation, bi-level positive airway pressure, continuous positive airway pressure, endotracheal tube, and laryngeal-mask-airway intubation.
- Describe criteria for, risks of, and complications due to endotracheal or laryngeal-mask-airway intubation, including strategies to reduce these risks.
- Compare and contrast optimal treatment strategies for acute respiratory failure in children with common acute respiratory conditions, including asthma, bronchiolitis, croup, and pneumonia.
Skills
Pediatric hospitalists should be able to:
- Perform and teach other health care providers to perform a thorough respiratory assessment of a child with acute respiratory distress.
- Identify early warning signs of acute respiratory distress and institute corrective actions and therapies to avert further deterioration.
- Identify patients with comorbidities and other risk factors for progression to acute respiratory failure.
- Order appropriate monitoring and relevant testing (such as radiographs and blood gases) and correctly interpret their results.
- Diagnose and initiate medical management for systemic causes of acute respiratory failure.
- Identify signs and symptoms of impending acute respiratory failure and activate local emergency response teams and/or transfer patients to an appropriate site with critical care services in a safe and efficient manner.
- Initiate oxygen supplementation via oxygen delivery devices and escalate as required to manage hypoxia and/or acute respiratory distress.
- Stabilize the airway, using non-invasive airway management techniques independently and invasive airway management in collaboration with other services.
- Demonstrate proficiency in basic management of patients with chronic respiratory support needs.
- Identify patients requiring subspecialty care and obtain timely consults.
Attitudes
Pediatric hospitalists should be able to:
- Acknowledge the importance of collaboration with patients, the family/caregivers, hospital staff, and subspecialists to ensure family-centered, coordinated hospital care for children with conditions at risk for acute respiratory failure.
- Realize the value of providing consultation for healthcare providers in community settings to ensure transport of patients to higher acuity settings as needed.
Systems Organization and Improvement
In order to improve efficiency and quality within their organizations, pediatric hospitalists should:
- Lead, coordinate, or participate in educational programs for the family/caregivers, hospital staff, and other healthcare providers regarding recognition of signs and symptoms of acute respiratory distress in children, particularly those at higher risk for acute respiratory failure.
- Work with hospital administration, hospital staff, subspecialists, and others to develop, implement, and assess outcomes of intervention strategies such as rapid response teams and early warning scores for hospitalized patients with deterioration in respiratory status in order to prevent adverse outcomes.
- Work with hospital administration, hospital staff, pharmacy, and others to ensure availability of medications and appropriately sized equipment for use in the management of acute respiratory failure in children.
Introduction
Respiratory failure is defined by inadequate gas exchange by the respiratory system that results in ineffective alveolar ventilation and/or oxygenation. Acute respiratory failure is more common in children than adults and is the primary cause of cardiopulmonary arrest in children. The differential diagnosis for acute respiratory failure in children is extensive, as failure may stem from any portion of the respiratory system or be a consequence of systemic disease. Pediatric hospitalists frequently encounter children with conditions affecting the respiratory system and should be able to anticipate, identify, and treat acute respiratory distress and acute respiratory failure in children, including those with chronic respiratory conditions and other comorbidities.
Knowledge
Pediatric hospitalists should be able to:
- Describe the structure and function respiratory system components, including upper and lower airways, muscles of respiration, and central and peripheral regulation systems.
- Explain developmental differences that contribute to acute respiratory failure in infants and young children, including upper airway size, lower airway growth and development, diaphragmatic muscle reserve, chest wall compliance, and respiratory regulatory center maturity.
- Discuss the basic principles of respiratory physiology, including the alveolar gas equation, minute ventilation, and alveolar-arterial gradient.
- Summarize the five causes of hypoxemia: ventilation-perfusion mismatch, hypoventilation, right to left shunt, diffusion impairment, and low inspired oxygen.
- Construct an age-based differential diagnosis for acute respiratory distress in children.
- List causes of poor respiratory muscle function, attending to age, neuromuscular disorders, central nervous system dysfunction, nerve injury, and others.
- Discuss comorbidities that place children at higher risk for acute respiratory failure.
- Summarize evaluation, monitoring, and treatment options for patients with worsening respiratory status, including mental status assessment, blood gas analysis, medications, and respiratory support.
- Describe the signs and symptoms of impending acute respiratory failure, including criteria for transfer to a higher level of care.
- Discuss the advantages and disadvantages of different supplemental oxygen delivery devices for children with and without medical complexity, such as low flow and heated high-flow nasal cannula, simple mask, partial rebreather or non-rebreather, and tracheostomy collar or mask.
- Summarize the modalities commonly available to support the airway and adequate gas exchange in children with worsening respiratory distress, including nasopharyngeal or oropharyngeal airways, bag-valve-mask ventilation, bi-level positive airway pressure, continuous positive airway pressure, endotracheal tube, and laryngeal-mask-airway intubation.
- Describe criteria for, risks of, and complications due to endotracheal or laryngeal-mask-airway intubation, including strategies to reduce these risks.
- Compare and contrast optimal treatment strategies for acute respiratory failure in children with common acute respiratory conditions, including asthma, bronchiolitis, croup, and pneumonia.
Skills
Pediatric hospitalists should be able to:
- Perform and teach other health care providers to perform a thorough respiratory assessment of a child with acute respiratory distress.
- Identify early warning signs of acute respiratory distress and institute corrective actions and therapies to avert further deterioration.
- Identify patients with comorbidities and other risk factors for progression to acute respiratory failure.
- Order appropriate monitoring and relevant testing (such as radiographs and blood gases) and correctly interpret their results.
- Diagnose and initiate medical management for systemic causes of acute respiratory failure.
- Identify signs and symptoms of impending acute respiratory failure and activate local emergency response teams and/or transfer patients to an appropriate site with critical care services in a safe and efficient manner.
- Initiate oxygen supplementation via oxygen delivery devices and escalate as required to manage hypoxia and/or acute respiratory distress.
- Stabilize the airway, using non-invasive airway management techniques independently and invasive airway management in collaboration with other services.
- Demonstrate proficiency in basic management of patients with chronic respiratory support needs.
- Identify patients requiring subspecialty care and obtain timely consults.
Attitudes
Pediatric hospitalists should be able to:
- Acknowledge the importance of collaboration with patients, the family/caregivers, hospital staff, and subspecialists to ensure family-centered, coordinated hospital care for children with conditions at risk for acute respiratory failure.
- Realize the value of providing consultation for healthcare providers in community settings to ensure transport of patients to higher acuity settings as needed.
Systems Organization and Improvement
In order to improve efficiency and quality within their organizations, pediatric hospitalists should:
- Lead, coordinate, or participate in educational programs for the family/caregivers, hospital staff, and other healthcare providers regarding recognition of signs and symptoms of acute respiratory distress in children, particularly those at higher risk for acute respiratory failure.
- Work with hospital administration, hospital staff, subspecialists, and others to develop, implement, and assess outcomes of intervention strategies such as rapid response teams and early warning scores for hospitalized patients with deterioration in respiratory status in order to prevent adverse outcomes.
- Work with hospital administration, hospital staff, pharmacy, and others to ensure availability of medications and appropriately sized equipment for use in the management of acute respiratory failure in children.
1. Samson RA, Schexnayder SM, Hazinski MF, et al. Part 3 Systematic approach to the seriously ill or injured child, Part 6 Recognition of Respiratory Distress and Failure, and Part 7 Management of Respiratory Distress and Failure. In: Pediatric Advanced Life Support: Provider Manual. Dallas, TX: American Heart Association; 2016;29-68; 113-170.
2. Hammer J. Acute respiratory failure in children. Paediatr Respir Rev. 2013; 14:64-69. https://doi.org/10.1016/j.prrv.2013.02.001.
1. Samson RA, Schexnayder SM, Hazinski MF, et al. Part 3 Systematic approach to the seriously ill or injured child, Part 6 Recognition of Respiratory Distress and Failure, and Part 7 Management of Respiratory Distress and Failure. In: Pediatric Advanced Life Support: Provider Manual. Dallas, TX: American Heart Association; 2016;29-68; 113-170.
2. Hammer J. Acute respiratory failure in children. Paediatr Respir Rev. 2013; 14:64-69. https://doi.org/10.1016/j.prrv.2013.02.001.
1.02 Common Clinical Diagnoses and Conditions: Acute Gastroenteritis
Introduction
Acute gastroenteritis (AGE) is one of the most common diseases of childhood. Admission to the hospital can be prevented in many cases with appropriate use of oral rehydration. Despite this, annual hospitalization rates in the United States have been reported to be as high 3 to 5 per 1000 US children, and the financial burden of emergency department care and hospitalization accounts for up to $350 million in costs annually. Although uncommon in developed countries, morbidity can be profound, and mortality can occur. Among hospitalized patients, complications including electrolyte abnormalities, sepsis, and malnutrition have been noted. Misdiagnosis of AGE may occur, particularly when vomiting is the predominant symptom, which can lead to inappropriate treatment for potentially life-threatening conditions. Pediatric hospitalists routinely encounter patients with AGE and should provide immediate medical care in an efficient and effective manner.
Knowledge
Pediatric hospitalists should be able to:
- Describe the signs, symptoms, and common or concerning complications of AGE, including electrolyte disturbances, dehydration, ileus, and hemolytic uremic syndrome.
- List the common pathogens and related epidemiologic factors for AGE depending upon age, immunization status, geographic location, and exposure and travel history.
- Discuss the pathophysiology of electrolyte disturbances in AGE.
- Discuss the indications for hospital admission, including the need for intravenous fluids, correction of fluid, electrolyte and acid base disturbances, close clinical monitoring, and/or further diagnostic evaluation.
- Discuss essential elements of the history for patients with AGE, including immunization status, water and food sources, method of food preparation, daycare attendance, and recent travel.
- Describe the elements of the physical examination that aid in the diagnosis of AGE and associated complications.
- Compare and contrast clinical findings associated with viral, bacterial, and parasitic AGE.
- Compare and contrast conditions with presentations like that of AGE or its complications, including critical medical and surgical diagnoses such as diabetic ketoacidosis, inborn errors of metabolism, malrotation with midgut volvulus, and bowel obstruction.
- Compare and contrast the differential diagnoses of isolated emesis, bilious emesis, and emesis with diarrhea.
- Describe the differences in approach toward diagnosis and treatment for patients with co-morbid conditions or immunosuppression.
- Discuss the role of infection control in the hospital, as well as public health reporting mandates.
- Describe the indications for diagnostic laboratory tests, including stool, blood, and urine studies, attending to age groups, predictive value of tests, and cost-effectiveness.
- Describe the indications and contraindications of the interventions used to manage the symptoms of AGE, including the role of oral rehydration solutions in the treatment of related dehydration.
- Discuss indications for specialty consultation, such as gastroenterology, nutrition, surgery, and others.
- Describe criteria for hospital discharge, including specific measures of clinical stability for safe care transition.
Skills
Pediatric hospitalists should be able to:
- Diagnose gastroenteritis by efficiently performing an accurate history and physical examination, determining if key features of the disease are present.
- Identify and correctly manage fluid, electrolyte, and acid base derangements.
- Assess patients efficiently and effectively for complications of gastroenteritis such as sepsis, ileus, and hemolytic uremic syndrome.
- Identify and appropriately treat patients at risk for AGE secondary to unusual pathogens.
- Direct a cost-effective and evidence-based evaluation and treatment plan, especially regarding laboratory studies, antibiotics, and oral or intravenous fluid resuscitation.
- Adhere consistently to infection control practices.
- Perform careful reassessments daily and as needed, note changes in clinical status, and respond with appropriate actions, taking care to consider alternative conditions as appropriate.
- Engage consultants efficiently when indicated.
- Communicate effectively with the family/caregivers and healthcare providers regarding findings and plans.
- Ensure coordination of care for diagnostic tests and treatment between subspecialists.
- Create a comprehensive discharge plan that can be expediently activated when appropriate.
Attitudes
Pediatric hospitalists should be able to:
- Realize responsibility for educating the family/caregivers on the natural course of the disease, identification and management of common complications, and infection control practices to manage expectations and decrease pathogen transmission.
- Ensure coordination of care for diagnostic tests and treatments between subspecialists.
- Exemplify and advocate for strict adherence to infection control practices.
- Exemplify effective communication with patients, the family/caregivers, and healthcare providers regarding findings, care plans, and anticipated health needs after discharge.
Systems Organization and Improvement
In order to improve efficiency and quality within their organizations, pediatric hospitalists should:
- Lead, coordinate, or participate in the development and implementation of cost-effective, safe, evidence-based care pathways to standardize the evaluation and management for hospitalized children with AGE.
- Collaborate with hospital administration to create and sustain a process to follow up on laboratory tests pending at discharge.
- Collaborate with institutional infection control practitioners to improve processes to prevent nosocomial infection related to gastroenteritis.
- Lead, coordinate, or participate in efforts to assure consistent public health reporting of appropriate infections and response to trends.
1. Chow CM, Leung AKC, Hon KL. Acute gastroenteritis: from guidelines to real life. Cli Exp Gastro. 2010; 3:97-112. https://doi.org/10.2147/ceg.s6554.
2. Freedman SB, Gouin S, Bhatt M, et al. Prospective assessment of practice pattern variations in the treatment of pediatric gastroenteritis. Pediatrics.2011;127(2) e287-e295. https://pediatrics.aappublications.org/content/127/2/e287. Accessed August 28, 2019.
Introduction
Acute gastroenteritis (AGE) is one of the most common diseases of childhood. Admission to the hospital can be prevented in many cases with appropriate use of oral rehydration. Despite this, annual hospitalization rates in the United States have been reported to be as high 3 to 5 per 1000 US children, and the financial burden of emergency department care and hospitalization accounts for up to $350 million in costs annually. Although uncommon in developed countries, morbidity can be profound, and mortality can occur. Among hospitalized patients, complications including electrolyte abnormalities, sepsis, and malnutrition have been noted. Misdiagnosis of AGE may occur, particularly when vomiting is the predominant symptom, which can lead to inappropriate treatment for potentially life-threatening conditions. Pediatric hospitalists routinely encounter patients with AGE and should provide immediate medical care in an efficient and effective manner.
Knowledge
Pediatric hospitalists should be able to:
- Describe the signs, symptoms, and common or concerning complications of AGE, including electrolyte disturbances, dehydration, ileus, and hemolytic uremic syndrome.
- List the common pathogens and related epidemiologic factors for AGE depending upon age, immunization status, geographic location, and exposure and travel history.
- Discuss the pathophysiology of electrolyte disturbances in AGE.
- Discuss the indications for hospital admission, including the need for intravenous fluids, correction of fluid, electrolyte and acid base disturbances, close clinical monitoring, and/or further diagnostic evaluation.
- Discuss essential elements of the history for patients with AGE, including immunization status, water and food sources, method of food preparation, daycare attendance, and recent travel.
- Describe the elements of the physical examination that aid in the diagnosis of AGE and associated complications.
- Compare and contrast clinical findings associated with viral, bacterial, and parasitic AGE.
- Compare and contrast conditions with presentations like that of AGE or its complications, including critical medical and surgical diagnoses such as diabetic ketoacidosis, inborn errors of metabolism, malrotation with midgut volvulus, and bowel obstruction.
- Compare and contrast the differential diagnoses of isolated emesis, bilious emesis, and emesis with diarrhea.
- Describe the differences in approach toward diagnosis and treatment for patients with co-morbid conditions or immunosuppression.
- Discuss the role of infection control in the hospital, as well as public health reporting mandates.
- Describe the indications for diagnostic laboratory tests, including stool, blood, and urine studies, attending to age groups, predictive value of tests, and cost-effectiveness.
- Describe the indications and contraindications of the interventions used to manage the symptoms of AGE, including the role of oral rehydration solutions in the treatment of related dehydration.
- Discuss indications for specialty consultation, such as gastroenterology, nutrition, surgery, and others.
- Describe criteria for hospital discharge, including specific measures of clinical stability for safe care transition.
Skills
Pediatric hospitalists should be able to:
- Diagnose gastroenteritis by efficiently performing an accurate history and physical examination, determining if key features of the disease are present.
- Identify and correctly manage fluid, electrolyte, and acid base derangements.
- Assess patients efficiently and effectively for complications of gastroenteritis such as sepsis, ileus, and hemolytic uremic syndrome.
- Identify and appropriately treat patients at risk for AGE secondary to unusual pathogens.
- Direct a cost-effective and evidence-based evaluation and treatment plan, especially regarding laboratory studies, antibiotics, and oral or intravenous fluid resuscitation.
- Adhere consistently to infection control practices.
- Perform careful reassessments daily and as needed, note changes in clinical status, and respond with appropriate actions, taking care to consider alternative conditions as appropriate.
- Engage consultants efficiently when indicated.
- Communicate effectively with the family/caregivers and healthcare providers regarding findings and plans.
- Ensure coordination of care for diagnostic tests and treatment between subspecialists.
- Create a comprehensive discharge plan that can be expediently activated when appropriate.
Attitudes
Pediatric hospitalists should be able to:
- Realize responsibility for educating the family/caregivers on the natural course of the disease, identification and management of common complications, and infection control practices to manage expectations and decrease pathogen transmission.
- Ensure coordination of care for diagnostic tests and treatments between subspecialists.
- Exemplify and advocate for strict adherence to infection control practices.
- Exemplify effective communication with patients, the family/caregivers, and healthcare providers regarding findings, care plans, and anticipated health needs after discharge.
Systems Organization and Improvement
In order to improve efficiency and quality within their organizations, pediatric hospitalists should:
- Lead, coordinate, or participate in the development and implementation of cost-effective, safe, evidence-based care pathways to standardize the evaluation and management for hospitalized children with AGE.
- Collaborate with hospital administration to create and sustain a process to follow up on laboratory tests pending at discharge.
- Collaborate with institutional infection control practitioners to improve processes to prevent nosocomial infection related to gastroenteritis.
- Lead, coordinate, or participate in efforts to assure consistent public health reporting of appropriate infections and response to trends.
Introduction
Acute gastroenteritis (AGE) is one of the most common diseases of childhood. Admission to the hospital can be prevented in many cases with appropriate use of oral rehydration. Despite this, annual hospitalization rates in the United States have been reported to be as high 3 to 5 per 1000 US children, and the financial burden of emergency department care and hospitalization accounts for up to $350 million in costs annually. Although uncommon in developed countries, morbidity can be profound, and mortality can occur. Among hospitalized patients, complications including electrolyte abnormalities, sepsis, and malnutrition have been noted. Misdiagnosis of AGE may occur, particularly when vomiting is the predominant symptom, which can lead to inappropriate treatment for potentially life-threatening conditions. Pediatric hospitalists routinely encounter patients with AGE and should provide immediate medical care in an efficient and effective manner.
Knowledge
Pediatric hospitalists should be able to:
- Describe the signs, symptoms, and common or concerning complications of AGE, including electrolyte disturbances, dehydration, ileus, and hemolytic uremic syndrome.
- List the common pathogens and related epidemiologic factors for AGE depending upon age, immunization status, geographic location, and exposure and travel history.
- Discuss the pathophysiology of electrolyte disturbances in AGE.
- Discuss the indications for hospital admission, including the need for intravenous fluids, correction of fluid, electrolyte and acid base disturbances, close clinical monitoring, and/or further diagnostic evaluation.
- Discuss essential elements of the history for patients with AGE, including immunization status, water and food sources, method of food preparation, daycare attendance, and recent travel.
- Describe the elements of the physical examination that aid in the diagnosis of AGE and associated complications.
- Compare and contrast clinical findings associated with viral, bacterial, and parasitic AGE.
- Compare and contrast conditions with presentations like that of AGE or its complications, including critical medical and surgical diagnoses such as diabetic ketoacidosis, inborn errors of metabolism, malrotation with midgut volvulus, and bowel obstruction.
- Compare and contrast the differential diagnoses of isolated emesis, bilious emesis, and emesis with diarrhea.
- Describe the differences in approach toward diagnosis and treatment for patients with co-morbid conditions or immunosuppression.
- Discuss the role of infection control in the hospital, as well as public health reporting mandates.
- Describe the indications for diagnostic laboratory tests, including stool, blood, and urine studies, attending to age groups, predictive value of tests, and cost-effectiveness.
- Describe the indications and contraindications of the interventions used to manage the symptoms of AGE, including the role of oral rehydration solutions in the treatment of related dehydration.
- Discuss indications for specialty consultation, such as gastroenterology, nutrition, surgery, and others.
- Describe criteria for hospital discharge, including specific measures of clinical stability for safe care transition.
Skills
Pediatric hospitalists should be able to:
- Diagnose gastroenteritis by efficiently performing an accurate history and physical examination, determining if key features of the disease are present.
- Identify and correctly manage fluid, electrolyte, and acid base derangements.
- Assess patients efficiently and effectively for complications of gastroenteritis such as sepsis, ileus, and hemolytic uremic syndrome.
- Identify and appropriately treat patients at risk for AGE secondary to unusual pathogens.
- Direct a cost-effective and evidence-based evaluation and treatment plan, especially regarding laboratory studies, antibiotics, and oral or intravenous fluid resuscitation.
- Adhere consistently to infection control practices.
- Perform careful reassessments daily and as needed, note changes in clinical status, and respond with appropriate actions, taking care to consider alternative conditions as appropriate.
- Engage consultants efficiently when indicated.
- Communicate effectively with the family/caregivers and healthcare providers regarding findings and plans.
- Ensure coordination of care for diagnostic tests and treatment between subspecialists.
- Create a comprehensive discharge plan that can be expediently activated when appropriate.
Attitudes
Pediatric hospitalists should be able to:
- Realize responsibility for educating the family/caregivers on the natural course of the disease, identification and management of common complications, and infection control practices to manage expectations and decrease pathogen transmission.
- Ensure coordination of care for diagnostic tests and treatments between subspecialists.
- Exemplify and advocate for strict adherence to infection control practices.
- Exemplify effective communication with patients, the family/caregivers, and healthcare providers regarding findings, care plans, and anticipated health needs after discharge.
Systems Organization and Improvement
In order to improve efficiency and quality within their organizations, pediatric hospitalists should:
- Lead, coordinate, or participate in the development and implementation of cost-effective, safe, evidence-based care pathways to standardize the evaluation and management for hospitalized children with AGE.
- Collaborate with hospital administration to create and sustain a process to follow up on laboratory tests pending at discharge.
- Collaborate with institutional infection control practitioners to improve processes to prevent nosocomial infection related to gastroenteritis.
- Lead, coordinate, or participate in efforts to assure consistent public health reporting of appropriate infections and response to trends.
1. Chow CM, Leung AKC, Hon KL. Acute gastroenteritis: from guidelines to real life. Cli Exp Gastro. 2010; 3:97-112. https://doi.org/10.2147/ceg.s6554.
2. Freedman SB, Gouin S, Bhatt M, et al. Prospective assessment of practice pattern variations in the treatment of pediatric gastroenteritis. Pediatrics.2011;127(2) e287-e295. https://pediatrics.aappublications.org/content/127/2/e287. Accessed August 28, 2019.
1. Chow CM, Leung AKC, Hon KL. Acute gastroenteritis: from guidelines to real life. Cli Exp Gastro. 2010; 3:97-112. https://doi.org/10.2147/ceg.s6554.
2. Freedman SB, Gouin S, Bhatt M, et al. Prospective assessment of practice pattern variations in the treatment of pediatric gastroenteritis. Pediatrics.2011;127(2) e287-e295. https://pediatrics.aappublications.org/content/127/2/e287. Accessed August 28, 2019.
1.01 Common Clinical Diagnoses and Conditions: Acute Abdominal Pain and Acute Abdomen
Introduction
Acute abdominal pain is a common presenting symptom of children and adolescents and prompts the consideration of an extensive differential diagnosis. Pediatric hospitalists frequently encounter children with acute abdominal pain. Acute abdominal pain may be due to common and self-limited medical conditions such as gastroenteritis or constipation, but it may also herald life threatening surgical conditions or systemic illness. The differential diagnosis of acute abdominal pain is broad, making a careful, skilled, and thorough history and physical examination essential in the evaluation of children presenting with this symptom. Identifying children with a true medical or surgical emergency is critical. Early diagnosis and treatment reduce morbidity, mortality, and length of hospital stay.
Knowledge
Pediatric hospitalists should be able to:
- Describe features of the medical history and physical examination that prompt specific and expedient diagnostic evaluation.
- Compare and contrast the differential diagnoses of acute abdominal pain and acute abdomen for children of varying ages.
- Describe and differentiate the clinical presentation consistent with intestinal obstruction from other causes of acute abdominal pain such as appendicitis, acute cholecystitis, and others.
- Differentiate etiologies of acute abdominal pain related to biological sex, such as testicular torsion, ovarian cyst rupture, ectopic pregnancy, and others.
- Discuss the presenting symptoms associated with abdominal emergencies (such as mid-gut volvulus and intussusception), including bilious emesis, bloody diarrhea, and severe pain.
- List the appropriate radiological studies for evaluation of various abdominal emergencies.
- Identify how the presentation of abdominal emergencies may differ in neonates and infants by including nonspecific symptoms, such as vomiting or lethargy.
- List conditions that may mimic the acute abdomen, including lower lobe pneumonia, diabetic ketoacidosis, and others.
- Discuss the benefits, risks, and limitations of commonly performed diagnostic studies, including abdominal radiography, ultrasonography, computed tomography, magnetic resonance imaging, and nuclear medicine scans, noting the benefits of and barriers to use of contrast enhancement for these studies.
- Describe the laboratory tests indicated to evaluate acute abdominal pain and acute abdomen.
- Discuss the importance of and indications for early surgical consultation in the child with an acute abdomen.
- Describe the principles of stabilization of the child with an acute abdomen, including volume resuscitation, antibiotics, and bowel decompression.
- Discuss the approach toward pain management in patients presenting with acute abdominal pain, including the impact of medication on serial exams.
- Describe indications for patient placement in various locations in the hospital system, such as an observation unit, surgical or medical ward, step-down, or intensive care unit.
- Discuss indications for patient transfer to a referral center, such as need for pediatric-specific services not available at the local facility.
Skills
Pediatric hospitalists should be able to:
- Obtain an accurate and thorough history to identify symptoms, triggers, and clinical course of acute abdominal pain and acute abdomen.
- Perform a physical exam to elicit signs of abdominal pain, differentiate findings of acute abdomen, and assess illness severity.
- Formulate a targeted differential diagnosis based on elements from the history and physical examination.
- Identify the child with an acute abdomen who requires emergent surgical consultation.
- Identify and manage the child with concomitant hypovolemia or sepsis requiring immediate medical stabilization.
- Direct an appropriate and cost-effective evaluation for acute abdominal pain and acute abdomen.
- Create and implement a treatment plan for non-surgical causes of abdominal pain.
- Order and correctly interpret basic diagnostic imaging and laboratory studies.
- Consult surgeons and other subspecialists effectively and efficiently when indicated.
- Provide pre- and post-operative general pediatric care for the child requiring surgery, including pain management, according to local practice parameters.
- Coordinate care with the primary care provider and subspecialists to arrange an appropriate transition plan for hospital discharge.
Attitudes
Pediatric hospitalists should be able to:
- Exemplify collaborative practice with subspecialists, including surgical teams and primary care providers, to ensure efficient care within the hospital setting and coordinated longitudinal care.
- Realize responsibility for promoting effective communication with patients, family/caregivers, and healthcare providers regarding findings and care plans.
Systems Organization and Improvement
In order to improve efficiency and quality within their organizations, pediatric hospitalists should:
- Lead, coordinate, or participate in education of healthcare providers, trainees, the family/caregivers regarding the signs and symptoms of the acute abdomen to encourage early detection and prompt evaluation.
- Lead, coordinate, or participate in a multidisciplinary team to provide optimal care for children with acute abdominal pain with and without acute abdomen.
- Lead, coordinate, or participate in institutional efforts to improve the expediency of diagnostic laboratory and radiographic studies, availability of specialty care, and other resources for children with acute abdominal pain and acute abdomen.
- Lead, coordinate, or participate in institutional efforts to develop surgical consultation or co-management models, clearly defining roles to ensure timely, high quality, and comprehensive care for pediatric patients requiring surgical care.
1. Baker RD. Acute Abdominal Pain. Peds Rev. 2018;39(3):130-139.
2. Tsao K. and Anderson K.T. Evaluation of abdominal pain in children. BMJ Best Practice. https://bestpractice.bmj.com/topics/en-us/787/diagnosis-approach. Accessed August 27, 2019.
Introduction
Acute abdominal pain is a common presenting symptom of children and adolescents and prompts the consideration of an extensive differential diagnosis. Pediatric hospitalists frequently encounter children with acute abdominal pain. Acute abdominal pain may be due to common and self-limited medical conditions such as gastroenteritis or constipation, but it may also herald life threatening surgical conditions or systemic illness. The differential diagnosis of acute abdominal pain is broad, making a careful, skilled, and thorough history and physical examination essential in the evaluation of children presenting with this symptom. Identifying children with a true medical or surgical emergency is critical. Early diagnosis and treatment reduce morbidity, mortality, and length of hospital stay.
Knowledge
Pediatric hospitalists should be able to:
- Describe features of the medical history and physical examination that prompt specific and expedient diagnostic evaluation.
- Compare and contrast the differential diagnoses of acute abdominal pain and acute abdomen for children of varying ages.
- Describe and differentiate the clinical presentation consistent with intestinal obstruction from other causes of acute abdominal pain such as appendicitis, acute cholecystitis, and others.
- Differentiate etiologies of acute abdominal pain related to biological sex, such as testicular torsion, ovarian cyst rupture, ectopic pregnancy, and others.
- Discuss the presenting symptoms associated with abdominal emergencies (such as mid-gut volvulus and intussusception), including bilious emesis, bloody diarrhea, and severe pain.
- List the appropriate radiological studies for evaluation of various abdominal emergencies.
- Identify how the presentation of abdominal emergencies may differ in neonates and infants by including nonspecific symptoms, such as vomiting or lethargy.
- List conditions that may mimic the acute abdomen, including lower lobe pneumonia, diabetic ketoacidosis, and others.
- Discuss the benefits, risks, and limitations of commonly performed diagnostic studies, including abdominal radiography, ultrasonography, computed tomography, magnetic resonance imaging, and nuclear medicine scans, noting the benefits of and barriers to use of contrast enhancement for these studies.
- Describe the laboratory tests indicated to evaluate acute abdominal pain and acute abdomen.
- Discuss the importance of and indications for early surgical consultation in the child with an acute abdomen.
- Describe the principles of stabilization of the child with an acute abdomen, including volume resuscitation, antibiotics, and bowel decompression.
- Discuss the approach toward pain management in patients presenting with acute abdominal pain, including the impact of medication on serial exams.
- Describe indications for patient placement in various locations in the hospital system, such as an observation unit, surgical or medical ward, step-down, or intensive care unit.
- Discuss indications for patient transfer to a referral center, such as need for pediatric-specific services not available at the local facility.
Skills
Pediatric hospitalists should be able to:
- Obtain an accurate and thorough history to identify symptoms, triggers, and clinical course of acute abdominal pain and acute abdomen.
- Perform a physical exam to elicit signs of abdominal pain, differentiate findings of acute abdomen, and assess illness severity.
- Formulate a targeted differential diagnosis based on elements from the history and physical examination.
- Identify the child with an acute abdomen who requires emergent surgical consultation.
- Identify and manage the child with concomitant hypovolemia or sepsis requiring immediate medical stabilization.
- Direct an appropriate and cost-effective evaluation for acute abdominal pain and acute abdomen.
- Create and implement a treatment plan for non-surgical causes of abdominal pain.
- Order and correctly interpret basic diagnostic imaging and laboratory studies.
- Consult surgeons and other subspecialists effectively and efficiently when indicated.
- Provide pre- and post-operative general pediatric care for the child requiring surgery, including pain management, according to local practice parameters.
- Coordinate care with the primary care provider and subspecialists to arrange an appropriate transition plan for hospital discharge.
Attitudes
Pediatric hospitalists should be able to:
- Exemplify collaborative practice with subspecialists, including surgical teams and primary care providers, to ensure efficient care within the hospital setting and coordinated longitudinal care.
- Realize responsibility for promoting effective communication with patients, family/caregivers, and healthcare providers regarding findings and care plans.
Systems Organization and Improvement
In order to improve efficiency and quality within their organizations, pediatric hospitalists should:
- Lead, coordinate, or participate in education of healthcare providers, trainees, the family/caregivers regarding the signs and symptoms of the acute abdomen to encourage early detection and prompt evaluation.
- Lead, coordinate, or participate in a multidisciplinary team to provide optimal care for children with acute abdominal pain with and without acute abdomen.
- Lead, coordinate, or participate in institutional efforts to improve the expediency of diagnostic laboratory and radiographic studies, availability of specialty care, and other resources for children with acute abdominal pain and acute abdomen.
- Lead, coordinate, or participate in institutional efforts to develop surgical consultation or co-management models, clearly defining roles to ensure timely, high quality, and comprehensive care for pediatric patients requiring surgical care.
Introduction
Acute abdominal pain is a common presenting symptom of children and adolescents and prompts the consideration of an extensive differential diagnosis. Pediatric hospitalists frequently encounter children with acute abdominal pain. Acute abdominal pain may be due to common and self-limited medical conditions such as gastroenteritis or constipation, but it may also herald life threatening surgical conditions or systemic illness. The differential diagnosis of acute abdominal pain is broad, making a careful, skilled, and thorough history and physical examination essential in the evaluation of children presenting with this symptom. Identifying children with a true medical or surgical emergency is critical. Early diagnosis and treatment reduce morbidity, mortality, and length of hospital stay.
Knowledge
Pediatric hospitalists should be able to:
- Describe features of the medical history and physical examination that prompt specific and expedient diagnostic evaluation.
- Compare and contrast the differential diagnoses of acute abdominal pain and acute abdomen for children of varying ages.
- Describe and differentiate the clinical presentation consistent with intestinal obstruction from other causes of acute abdominal pain such as appendicitis, acute cholecystitis, and others.
- Differentiate etiologies of acute abdominal pain related to biological sex, such as testicular torsion, ovarian cyst rupture, ectopic pregnancy, and others.
- Discuss the presenting symptoms associated with abdominal emergencies (such as mid-gut volvulus and intussusception), including bilious emesis, bloody diarrhea, and severe pain.
- List the appropriate radiological studies for evaluation of various abdominal emergencies.
- Identify how the presentation of abdominal emergencies may differ in neonates and infants by including nonspecific symptoms, such as vomiting or lethargy.
- List conditions that may mimic the acute abdomen, including lower lobe pneumonia, diabetic ketoacidosis, and others.
- Discuss the benefits, risks, and limitations of commonly performed diagnostic studies, including abdominal radiography, ultrasonography, computed tomography, magnetic resonance imaging, and nuclear medicine scans, noting the benefits of and barriers to use of contrast enhancement for these studies.
- Describe the laboratory tests indicated to evaluate acute abdominal pain and acute abdomen.
- Discuss the importance of and indications for early surgical consultation in the child with an acute abdomen.
- Describe the principles of stabilization of the child with an acute abdomen, including volume resuscitation, antibiotics, and bowel decompression.
- Discuss the approach toward pain management in patients presenting with acute abdominal pain, including the impact of medication on serial exams.
- Describe indications for patient placement in various locations in the hospital system, such as an observation unit, surgical or medical ward, step-down, or intensive care unit.
- Discuss indications for patient transfer to a referral center, such as need for pediatric-specific services not available at the local facility.
Skills
Pediatric hospitalists should be able to:
- Obtain an accurate and thorough history to identify symptoms, triggers, and clinical course of acute abdominal pain and acute abdomen.
- Perform a physical exam to elicit signs of abdominal pain, differentiate findings of acute abdomen, and assess illness severity.
- Formulate a targeted differential diagnosis based on elements from the history and physical examination.
- Identify the child with an acute abdomen who requires emergent surgical consultation.
- Identify and manage the child with concomitant hypovolemia or sepsis requiring immediate medical stabilization.
- Direct an appropriate and cost-effective evaluation for acute abdominal pain and acute abdomen.
- Create and implement a treatment plan for non-surgical causes of abdominal pain.
- Order and correctly interpret basic diagnostic imaging and laboratory studies.
- Consult surgeons and other subspecialists effectively and efficiently when indicated.
- Provide pre- and post-operative general pediatric care for the child requiring surgery, including pain management, according to local practice parameters.
- Coordinate care with the primary care provider and subspecialists to arrange an appropriate transition plan for hospital discharge.
Attitudes
Pediatric hospitalists should be able to:
- Exemplify collaborative practice with subspecialists, including surgical teams and primary care providers, to ensure efficient care within the hospital setting and coordinated longitudinal care.
- Realize responsibility for promoting effective communication with patients, family/caregivers, and healthcare providers regarding findings and care plans.
Systems Organization and Improvement
In order to improve efficiency and quality within their organizations, pediatric hospitalists should:
- Lead, coordinate, or participate in education of healthcare providers, trainees, the family/caregivers regarding the signs and symptoms of the acute abdomen to encourage early detection and prompt evaluation.
- Lead, coordinate, or participate in a multidisciplinary team to provide optimal care for children with acute abdominal pain with and without acute abdomen.
- Lead, coordinate, or participate in institutional efforts to improve the expediency of diagnostic laboratory and radiographic studies, availability of specialty care, and other resources for children with acute abdominal pain and acute abdomen.
- Lead, coordinate, or participate in institutional efforts to develop surgical consultation or co-management models, clearly defining roles to ensure timely, high quality, and comprehensive care for pediatric patients requiring surgical care.
1. Baker RD. Acute Abdominal Pain. Peds Rev. 2018;39(3):130-139.
2. Tsao K. and Anderson K.T. Evaluation of abdominal pain in children. BMJ Best Practice. https://bestpractice.bmj.com/topics/en-us/787/diagnosis-approach. Accessed August 27, 2019.
1. Baker RD. Acute Abdominal Pain. Peds Rev. 2018;39(3):130-139.
2. Tsao K. and Anderson K.T. Evaluation of abdominal pain in children. BMJ Best Practice. https://bestpractice.bmj.com/topics/en-us/787/diagnosis-approach. Accessed August 27, 2019.