Allowed Publications
Slot System
Featured Buckets
Featured Buckets Admin

Legal Issues for the Gastroenterologist: Part II

Article Type
Changed

 

In the previous issue of The New Gastroenterologist, we discussed statistics and the basis on which most gastroenterologists are sued as well as what you can do to minimize this risk. In this second article, we discuss steps to assist in your defense in the event you have been sued. The following suggestions are based on our experience as defense attorneys who practice in the arena of medical malpractice.

Peter J. Hoffman
If you have been sued, it is imperative that you notify your insurer immediately, as this may be required under your policy for coverage. It is also best practice to notify the carrier and/or the hospital (if it occurred at the hospital) of any incident or serious event, bad outcome, or letters from lawyers representing the patients. This allows for early investigation and, in some cases, intervention.

Do not, under any circumstances, add or alter the plaintiff’s medical records. Although you have continued access to electronic medical records, accessing or altering these documents leaves an electronic trail. Attorneys are now frequently requesting an “audit trail” during discovery, which shows who and when someone accessed or altered relevant medical records. Additionally, it is likely that the plaintiff’s counsel has already obtained and reviewed records for their client. As such, counsel will notice any alterations and will require an explanation as to the same. If you did alter any medical records, it is important that you notify your attorney about the specifics of such.

Andrew J. Bond
You should not discuss anything about the case with anyone other than your spouse and attorney. This will prevent plaintiff’s counsel from deposing additional witnesses and limit the amount of people potentially forced to testify.

After you have secured an attorney, it is critical that you arrange a meeting to develop a positive relationship early in the litigation process. This is important for many reasons. A medical malpractice case can be a long and arduous process which requires that you be involved with your attorney during the course of the litigation. For the attorney-client relationship to be successful, it is imperative that you know and feel comfortable with your attorney and develop confidence and trust in her. Without this trust, it will be difficult for you to accept various decisions or suggestions that the attorney believes are in your best interest. Conversely, the attorney should get to know you and understand your background, as this will assist in your representation.

A good relationship with you will also aid your attorney in educating herself on medical concepts relating to your case. Remember, your attorney most likely has not attended medical school and many of the medical concepts will initially be new to her. By the time trial arrives, however, your attorney will be very familiar with the medical issues in your case. This learning process can be expedited with your assistance and research.

Andrew F. Albero
Finally, be sure to respond fully and honestly to questions from your attorney, regardless of whether you view it as harmful, irrelevant, or unimportant. Anything you tell your attorney is confidential and protected by privilege. Your attorney is your ally. It is her job to help you. Thus, it is essential that you respond fully and honestly to all questions posed by your attorney and disclose all possibly relevant information.
 

Your deposition

At some point during the lawsuit, the plaintiff’s attorney will take your deposition. The plaintiff’s attorney will strive to obtain concessions that establish the standard of care, breach of the standard, causation, and damages. Your deposition is not the time for you to provide explanations. It is the time for you to concisely answer specific questions posed by counsel without volunteering any additional information. Ultimately, trials build on what occurs during depositions. Preparation is key. Be open to advice or criticisms from your lawyer. Try to eliminate any quirks or habits that interfere with the substance of your testimony or perceived credibility. A deposition is not a casual conversation, nor is it a test of your memory. Limit your answers to personal knowledge; never guess or speculate. If you do not know the answer to a question, or do not remember something, it is perfectly acceptable for you to say so. Only answer questions that you understand. You are allowed to ask the plaintiff’s counsel to repeat or rephrase questions.

Alexandra Rogin
Once you have answered a question, stick to your answer if it is accurate. It is fine to change an answer, but do not change it simply because the plaintiff’s counsel is pushing you to do so. Aggressive interrogation by opposing counsel may occur. Never argue or quibble with the plaintiff’s lawyer; leave all arguing to your lawyer. A witness who is calm, courteous, and confident is more likely to appear credible. The plaintiff’s attorney may request that your deposition be videotaped. If this is the case, be mindful of your mannerisms, tone of voice, and appearance. The videotape may end up being played in front of a jury.

Finally, and most importantly, always tell the truth. Discuss any anticipated issues or concerns with your lawyer before your deposition.
 
 

 

Preparing for trial

Brittany C. Wakim
A trial can last anywhere from 1 to 3 weeks. Your daily presence (including at the jury selection before the trial begins) is mandatory and in your own best interest. Your lawyer will have little control over the date on which the trial will occur. That date will be set by a judge, who will not be sympathetic to your scheduling problems. Be prepared to cancel patients’ appointments and any procedures already scheduled. The jury’s perception of you can be influenced by your presence and demonstrated dedication to your defense.

Conclusion

In summary, remember that there are things you can do both before and after you are sued to minimize litigation and its impact. As mentioned previously, before a lawsuit, and as a regular part of your practice, it is important that you stay current with medical advances, that you take the time to create a relationship with your patients involving quality communication, and that you thoroughly and legibly document all aspects of care provided. After a suit is filed against you, make sure you notify your insurer immediately, do not alter any records or discuss the case with anyone other than your lawyer or spouse, and do all you can to create a productive and honest relationship with your lawyer. This relationship will be invaluable as you do the difficult and time-consuming work of preparing for your deposition and trial, and it can help you endure and successfully navigate the litigation process.

The Importance of Follow-Up: Further Advice on How to Decrease the Risk of Being Sued

A common basis for establishing a malpractice liability claim against a physician is the failure to follow-up or track a patient’s test results. In today’s world, there is an increasing number of moving parts involved in any given patient’s care. A particular patient may treat with numerous physicians, all of whom use different record systems. Electronic medical record systems have made records more accessible and easier to track, but they also present a new set of challenges.


Every physician needs to determine how they plan to track test results. The ideal system would allow a physician to quickly get back any lab or diagnostic test that he or she orders. All staff members should know how the physician’s system works. Otherwise, test results might accidentally be filed before the physician reviews them or a miscommunication could prevent test results from being delivered. Whatever choice of system, it is key to follow and effectively use the program every time.


Additionally, it can be beneficial to let the patient know when he or she can expect to hear about their results, as failure to keep the patient reasonably informed can create a new set of patient concerns and anxiety. Ultimately, establishing a well-defined system for record-tracking can help physicians avoid malpractice liability claims because of a failure to follow-up.

Publications
Sections

 

In the previous issue of The New Gastroenterologist, we discussed statistics and the basis on which most gastroenterologists are sued as well as what you can do to minimize this risk. In this second article, we discuss steps to assist in your defense in the event you have been sued. The following suggestions are based on our experience as defense attorneys who practice in the arena of medical malpractice.

Peter J. Hoffman
If you have been sued, it is imperative that you notify your insurer immediately, as this may be required under your policy for coverage. It is also best practice to notify the carrier and/or the hospital (if it occurred at the hospital) of any incident or serious event, bad outcome, or letters from lawyers representing the patients. This allows for early investigation and, in some cases, intervention.

Do not, under any circumstances, add or alter the plaintiff’s medical records. Although you have continued access to electronic medical records, accessing or altering these documents leaves an electronic trail. Attorneys are now frequently requesting an “audit trail” during discovery, which shows who and when someone accessed or altered relevant medical records. Additionally, it is likely that the plaintiff’s counsel has already obtained and reviewed records for their client. As such, counsel will notice any alterations and will require an explanation as to the same. If you did alter any medical records, it is important that you notify your attorney about the specifics of such.

Andrew J. Bond
You should not discuss anything about the case with anyone other than your spouse and attorney. This will prevent plaintiff’s counsel from deposing additional witnesses and limit the amount of people potentially forced to testify.

After you have secured an attorney, it is critical that you arrange a meeting to develop a positive relationship early in the litigation process. This is important for many reasons. A medical malpractice case can be a long and arduous process which requires that you be involved with your attorney during the course of the litigation. For the attorney-client relationship to be successful, it is imperative that you know and feel comfortable with your attorney and develop confidence and trust in her. Without this trust, it will be difficult for you to accept various decisions or suggestions that the attorney believes are in your best interest. Conversely, the attorney should get to know you and understand your background, as this will assist in your representation.

A good relationship with you will also aid your attorney in educating herself on medical concepts relating to your case. Remember, your attorney most likely has not attended medical school and many of the medical concepts will initially be new to her. By the time trial arrives, however, your attorney will be very familiar with the medical issues in your case. This learning process can be expedited with your assistance and research.

Andrew F. Albero
Finally, be sure to respond fully and honestly to questions from your attorney, regardless of whether you view it as harmful, irrelevant, or unimportant. Anything you tell your attorney is confidential and protected by privilege. Your attorney is your ally. It is her job to help you. Thus, it is essential that you respond fully and honestly to all questions posed by your attorney and disclose all possibly relevant information.
 

Your deposition

At some point during the lawsuit, the plaintiff’s attorney will take your deposition. The plaintiff’s attorney will strive to obtain concessions that establish the standard of care, breach of the standard, causation, and damages. Your deposition is not the time for you to provide explanations. It is the time for you to concisely answer specific questions posed by counsel without volunteering any additional information. Ultimately, trials build on what occurs during depositions. Preparation is key. Be open to advice or criticisms from your lawyer. Try to eliminate any quirks or habits that interfere with the substance of your testimony or perceived credibility. A deposition is not a casual conversation, nor is it a test of your memory. Limit your answers to personal knowledge; never guess or speculate. If you do not know the answer to a question, or do not remember something, it is perfectly acceptable for you to say so. Only answer questions that you understand. You are allowed to ask the plaintiff’s counsel to repeat or rephrase questions.

Alexandra Rogin
Once you have answered a question, stick to your answer if it is accurate. It is fine to change an answer, but do not change it simply because the plaintiff’s counsel is pushing you to do so. Aggressive interrogation by opposing counsel may occur. Never argue or quibble with the plaintiff’s lawyer; leave all arguing to your lawyer. A witness who is calm, courteous, and confident is more likely to appear credible. The plaintiff’s attorney may request that your deposition be videotaped. If this is the case, be mindful of your mannerisms, tone of voice, and appearance. The videotape may end up being played in front of a jury.

Finally, and most importantly, always tell the truth. Discuss any anticipated issues or concerns with your lawyer before your deposition.
 
 

 

Preparing for trial

Brittany C. Wakim
A trial can last anywhere from 1 to 3 weeks. Your daily presence (including at the jury selection before the trial begins) is mandatory and in your own best interest. Your lawyer will have little control over the date on which the trial will occur. That date will be set by a judge, who will not be sympathetic to your scheduling problems. Be prepared to cancel patients’ appointments and any procedures already scheduled. The jury’s perception of you can be influenced by your presence and demonstrated dedication to your defense.

Conclusion

In summary, remember that there are things you can do both before and after you are sued to minimize litigation and its impact. As mentioned previously, before a lawsuit, and as a regular part of your practice, it is important that you stay current with medical advances, that you take the time to create a relationship with your patients involving quality communication, and that you thoroughly and legibly document all aspects of care provided. After a suit is filed against you, make sure you notify your insurer immediately, do not alter any records or discuss the case with anyone other than your lawyer or spouse, and do all you can to create a productive and honest relationship with your lawyer. This relationship will be invaluable as you do the difficult and time-consuming work of preparing for your deposition and trial, and it can help you endure and successfully navigate the litigation process.

The Importance of Follow-Up: Further Advice on How to Decrease the Risk of Being Sued

A common basis for establishing a malpractice liability claim against a physician is the failure to follow-up or track a patient’s test results. In today’s world, there is an increasing number of moving parts involved in any given patient’s care. A particular patient may treat with numerous physicians, all of whom use different record systems. Electronic medical record systems have made records more accessible and easier to track, but they also present a new set of challenges.


Every physician needs to determine how they plan to track test results. The ideal system would allow a physician to quickly get back any lab or diagnostic test that he or she orders. All staff members should know how the physician’s system works. Otherwise, test results might accidentally be filed before the physician reviews them or a miscommunication could prevent test results from being delivered. Whatever choice of system, it is key to follow and effectively use the program every time.


Additionally, it can be beneficial to let the patient know when he or she can expect to hear about their results, as failure to keep the patient reasonably informed can create a new set of patient concerns and anxiety. Ultimately, establishing a well-defined system for record-tracking can help physicians avoid malpractice liability claims because of a failure to follow-up.

 

In the previous issue of The New Gastroenterologist, we discussed statistics and the basis on which most gastroenterologists are sued as well as what you can do to minimize this risk. In this second article, we discuss steps to assist in your defense in the event you have been sued. The following suggestions are based on our experience as defense attorneys who practice in the arena of medical malpractice.

Peter J. Hoffman
If you have been sued, it is imperative that you notify your insurer immediately, as this may be required under your policy for coverage. It is also best practice to notify the carrier and/or the hospital (if it occurred at the hospital) of any incident or serious event, bad outcome, or letters from lawyers representing the patients. This allows for early investigation and, in some cases, intervention.

Do not, under any circumstances, add or alter the plaintiff’s medical records. Although you have continued access to electronic medical records, accessing or altering these documents leaves an electronic trail. Attorneys are now frequently requesting an “audit trail” during discovery, which shows who and when someone accessed or altered relevant medical records. Additionally, it is likely that the plaintiff’s counsel has already obtained and reviewed records for their client. As such, counsel will notice any alterations and will require an explanation as to the same. If you did alter any medical records, it is important that you notify your attorney about the specifics of such.

Andrew J. Bond
You should not discuss anything about the case with anyone other than your spouse and attorney. This will prevent plaintiff’s counsel from deposing additional witnesses and limit the amount of people potentially forced to testify.

After you have secured an attorney, it is critical that you arrange a meeting to develop a positive relationship early in the litigation process. This is important for many reasons. A medical malpractice case can be a long and arduous process which requires that you be involved with your attorney during the course of the litigation. For the attorney-client relationship to be successful, it is imperative that you know and feel comfortable with your attorney and develop confidence and trust in her. Without this trust, it will be difficult for you to accept various decisions or suggestions that the attorney believes are in your best interest. Conversely, the attorney should get to know you and understand your background, as this will assist in your representation.

A good relationship with you will also aid your attorney in educating herself on medical concepts relating to your case. Remember, your attorney most likely has not attended medical school and many of the medical concepts will initially be new to her. By the time trial arrives, however, your attorney will be very familiar with the medical issues in your case. This learning process can be expedited with your assistance and research.

Andrew F. Albero
Finally, be sure to respond fully and honestly to questions from your attorney, regardless of whether you view it as harmful, irrelevant, or unimportant. Anything you tell your attorney is confidential and protected by privilege. Your attorney is your ally. It is her job to help you. Thus, it is essential that you respond fully and honestly to all questions posed by your attorney and disclose all possibly relevant information.
 

Your deposition

At some point during the lawsuit, the plaintiff’s attorney will take your deposition. The plaintiff’s attorney will strive to obtain concessions that establish the standard of care, breach of the standard, causation, and damages. Your deposition is not the time for you to provide explanations. It is the time for you to concisely answer specific questions posed by counsel without volunteering any additional information. Ultimately, trials build on what occurs during depositions. Preparation is key. Be open to advice or criticisms from your lawyer. Try to eliminate any quirks or habits that interfere with the substance of your testimony or perceived credibility. A deposition is not a casual conversation, nor is it a test of your memory. Limit your answers to personal knowledge; never guess or speculate. If you do not know the answer to a question, or do not remember something, it is perfectly acceptable for you to say so. Only answer questions that you understand. You are allowed to ask the plaintiff’s counsel to repeat or rephrase questions.

Alexandra Rogin
Once you have answered a question, stick to your answer if it is accurate. It is fine to change an answer, but do not change it simply because the plaintiff’s counsel is pushing you to do so. Aggressive interrogation by opposing counsel may occur. Never argue or quibble with the plaintiff’s lawyer; leave all arguing to your lawyer. A witness who is calm, courteous, and confident is more likely to appear credible. The plaintiff’s attorney may request that your deposition be videotaped. If this is the case, be mindful of your mannerisms, tone of voice, and appearance. The videotape may end up being played in front of a jury.

Finally, and most importantly, always tell the truth. Discuss any anticipated issues or concerns with your lawyer before your deposition.
 
 

 

Preparing for trial

Brittany C. Wakim
A trial can last anywhere from 1 to 3 weeks. Your daily presence (including at the jury selection before the trial begins) is mandatory and in your own best interest. Your lawyer will have little control over the date on which the trial will occur. That date will be set by a judge, who will not be sympathetic to your scheduling problems. Be prepared to cancel patients’ appointments and any procedures already scheduled. The jury’s perception of you can be influenced by your presence and demonstrated dedication to your defense.

Conclusion

In summary, remember that there are things you can do both before and after you are sued to minimize litigation and its impact. As mentioned previously, before a lawsuit, and as a regular part of your practice, it is important that you stay current with medical advances, that you take the time to create a relationship with your patients involving quality communication, and that you thoroughly and legibly document all aspects of care provided. After a suit is filed against you, make sure you notify your insurer immediately, do not alter any records or discuss the case with anyone other than your lawyer or spouse, and do all you can to create a productive and honest relationship with your lawyer. This relationship will be invaluable as you do the difficult and time-consuming work of preparing for your deposition and trial, and it can help you endure and successfully navigate the litigation process.

The Importance of Follow-Up: Further Advice on How to Decrease the Risk of Being Sued

A common basis for establishing a malpractice liability claim against a physician is the failure to follow-up or track a patient’s test results. In today’s world, there is an increasing number of moving parts involved in any given patient’s care. A particular patient may treat with numerous physicians, all of whom use different record systems. Electronic medical record systems have made records more accessible and easier to track, but they also present a new set of challenges.


Every physician needs to determine how they plan to track test results. The ideal system would allow a physician to quickly get back any lab or diagnostic test that he or she orders. All staff members should know how the physician’s system works. Otherwise, test results might accidentally be filed before the physician reviews them or a miscommunication could prevent test results from being delivered. Whatever choice of system, it is key to follow and effectively use the program every time.


Additionally, it can be beneficial to let the patient know when he or she can expect to hear about their results, as failure to keep the patient reasonably informed can create a new set of patient concerns and anxiety. Ultimately, establishing a well-defined system for record-tracking can help physicians avoid malpractice liability claims because of a failure to follow-up.

Publications
Publications
Article Type
Sections
Disallow All Ads
Content Gating
No Gating (article Unlocked/Free)
Alternative CME
Disqus Comments
Default

The Light at the End of the Tunnel: Recent Advances in Endoscopic Retrograde Cholangiopancreatograpy

Article Type
Changed

 

Introduction

Direct visualization of the biliary ductal system is quickly gaining importance among gastroenterologists. Since the inception of cholangioscopy in the 1970s, the technology has progressed, allowing for ease of use, better visualization, and a growing number of indications. Conventional endoscopic retrograde cholangiopancreatography (ERCP) is successful for removal of bile duct stones (with success rates over 90%);1 however, its use in the evaluation of potential biliary neoplasia has been somewhat disappointing. The diagnostic yield of ERCP-guided biliary brushings can range from 30% to 40%.2-4 An alternative to ERCP-guided biliary brushings for biliary strictures is endoscopic ultrasound (EUS)-directed fine needle aspiration (FNA), but the reported sensitivity remains poor, ranging from 43% to 77% with negative predictive values of less than 30%.5-7 These results leave much to be desired for diagnostic yield.

Dr. William Preston Sonnier
The newest method of evaluating pancreaticobiliary pathology is with direct visualization using cholangioscopy. The advantages of this modality include the ability to obtain direct visualization as well as targeted biopsies of suspicious lesions. The first fiberoptic cholangioscope was introduced in 1965 and the first use of peroral cholangioscopy was reported in in the mid 1970s.8,9 Early models were limited by their delicacy, relative immmobility, lack of dedicated irrigation channel, and need for two endoscopists using a “mother baby” design. Fiberoptic single-operator cholangiopancreatoscopy (FSOCP) was first introduced in 2006 by Boston Scientific (Marlborough, MA).10 It was designed to address the previously stated shortcomings of the first-generation cholangioscopy devices. Since its introduction, it has gained worldwide popularity in the diagnosis and management of pancreaticobiliary pathology and complex biliary stones.

Dr. Meir Mizrahi
The initial model employed a reusable fiber optic optical probe, a disposable cholangioscope access and delivery catheter, and disposable small-caliber biopsy forceps. The components can be introduced through a duodenoscope that has a minimum working channel diameter of 3.4 mm. The original FSOCP catheter is attached to the duodenoscope by a silastic belt just below the operating channel, allowing for single operator use. The access and delivery catheter has an outer diameter of 10 F and three separate ports: an optical port, two dedicated 0.6-mm irrigation channels, and a 1.2-mm accessory channel that accepts various accessories including the small-caliber biopsy forceps, electrohydraulic lithotripsy (EHL) fibers, or a holmium laser probe. The catheter has fourway tip deflection. The fiberoptic probe does have limitations, including its limited field of view, fragility of the fiber, and need for adjustment of the lens focus. Because of these limitations, a digital single-operator cholangioscope (DSOCP) was developed and introduced in 2014 (Boston Scientific, Marlborough, MA). In the DSOCP system, the light is generated by two independent light-emitting diodes and a complementary metal-oxide semiconductor digital camera chip. Improvements included a wider 120-degree field of view, dedicated irrigation and aspiration channels/connections, suction channel, and redesigned accessory channel. The cholangioscope is entirely disposable. The processor receives video signals from the catheter, processes the signals and outputs video images to an attached monitor. The newer digital-based platform has shown promising results, including higher diagnostic yield and shorter ERCP completion time when compared with similarly performed procedures using the fiberoptic-based platform.11

Clinical indications

Dr. Douglas K. Pleskow
Direct visualization and biopsy of indeterminate biliary strictures has resulted in greatly improved diagnostic accuracy and collection of adequate tissue (Figures. 1,2). In a recent systematic review, the pooled sensitivity and specificity of cholangioscopy-guided biopsies in the diagnosis of malignant biliary strictures was 61% (95% confidence interval, 55%-65%) and 98% (95% CI, 96%-99%), respectively. Direct comparison of small-caliber direct biopsies with standard brushings and biopsies showed small-caliber direct biopsies having a sensitivity of 76.5% versus 5.8% and 29% with standard brushes and biopsies, respectively.12 The pooled sensitivity and specificity of six studies using cholangioscopy with targeted biopsies in the diagnosis of cholangiocarcinoma was 66.2% and 97.0%, respectively.12 Studies have shown that small-caliber forceps obtains tissue adequate for pathologic evaluation in 82%-97% of biopsy samples retrieved.13-17 Three prospective trials have evaluated the diagnostic accuracy of small-caliber forceps for indeterminate biliary lesions. The accuracy ranged from 72% to 85% with a sensitivity of 49%-82%, specificity of 82%-100%, positive predictive value of 100%, and negative predictive value of 69%-100%.15-17 The improved diagnostic accuracy of cholangioscopy for indeterminate biliary strictures stems from its direct visualization ability. Traditional sampling techniques (cytology brushings and fluoroscopically guided biopsies) are plagued by low sensitivity and negative predictive value caused by a relatively high false-positive rate.

DSOCP appears to have improved accuracy over fiberoptic equipment. In a recent multicenter observational study in patients undergoing digital cholangioscopy, the guided biopsies resulted in adequate tissue for histologic evaluation in 98% of patients. In addition, the sensitivity and specificity of digital cholangioscope-guided biopsies for diagnosis of malignancy was 85% and 100%, respectively.11

Dr. Sonnier, Dr. Mizrahi, and Dr. Pleskow
Figure 1: Intraductal lesion seen after stone clearance by EHL.
Conventional ERCP is successful in most cases of biliary stone extraction but, in 5%-10% of cases, stones can be difficult to remove because of size, location above strictures, or adherence to the bile duct wall18 (Figure 3). In addition, lithotripsy with standard fluoroscopic guidance can cause stone fragments to get lost. In one study, 29% of ERCP-lost gallstones were diagnosed by post-hoc cholangioscopy.19 A number of studies have documented a high success rate of FSOCP- or DSOCP-guided lithotripsy, ranging from 90% to 100% (13,14,16,20,21). In addition cholangioscopy can circumvent the need for mechanical lithotripsy. EHL is used for the majority of cases, but use of a holium laser has also been described.20,21 The dedicated irrigation channels on the FSOCP/DSOCP system give the ability to continuously fill the biliary system with fluid, which is required for EHL (Figures 4,5).

Dr. Sonnier, Dr. Mizrahi, and Dr. Pleskow
Figure 2: Intraductal lesion seen in direct visualization, intraductal endoscopic ultrasound confirmed the presence of varice.
Diagnostic pancreatoscopy has advantages in the diagnosis and future management of malignancies and intraductal papillary mucinous neoplasms (IPMNs). In addition, pancreatic duct stones can easily be managed with digital pancreatoscopy and lithotripsy (EHL or laser lithotripsy). A study that included 115 patients that were followed for at least 2 years showed that pancreatoscopy was able to diagnose 63% of pancreatic cancers, 80% of benign strictures, and 95% of intraductal papillary mucinous neoplasms based on visual appearances. The authors were able to discern neoplasia based on visual findings, including coarse or granular mucosa, protrusion, papillary tumor, and tumor vessel.22 In a similar study, patients with confirmed intraductal papilliary mucinous neoplasms (IPMN) underwent peroral pancreatoscopy and/or intraductal ultrasound preoperatively. The detected protruding lesions were classified into five groups: granular mucosa, fish-egg with or without vascular images, villous type, and vegetative type. The diagnostic accuracy of peroral pancreatoscopy in differentiating benign IPMN from malignant ones was 88% with a sensitivity and specificity of 100% and 71% in the main duct type, respectively, and sensitivities and specificities of 43% and 100% of branch type, respectively.23

Figure 3: Large intraductal stone noted on DSOCP.
DSOCP also has therapeutic implications for other pancreatic diseases. Pancreatic duct obstruction can be caused by stones and strictures. A large multicenter study of 1,000 patients with chronic pancreatitis revealed obstruction of the main pancreatic duct (MPD) in 50%; with 32% being caused by strictures and stones, while 18% were due solely to stones.24 Currently accepted treatments for pancreaticolithiasis include extracorporeal shock wave lithotripsy, ERCP with stone clearance, and stenting or surgery (pancreaticojejunostomy) but these techniques have limitations and can incur morbidity.

Figure 4: Demonstration of EHL probe. The setting as noted should be 100 watts and 20 shots per cycle.
DSOCP has recently been evaluated as an alternative technique in treating MPD stones. In a recent study, Bekkali et al reviewed their 3-year experience of digital pancreatoscopy and EHL for pancreatic duct stones. Of the pancreatoscopy procedures performed, 7% were for pancreatic stones. All the patients had painful chronic pancreatitis, radiographic evidence of a dilated pancreatic duct, and MPD stone disease. Stone fragmentation and pancreatic duct decompression were achieved in 83% without complications. Two patients required two EHL procedures to achieve clearance. In the single patient with failed clearance, pancreatoscopy revealed the stone to be in adjacent parenchyma and not in the pancreatic duct. All patients with successful pancreatoscopy and EHL had pain relief and marked improvement during follow up.25

Other less common diagnostic indications for DSOCP include evaluation of cystic lesions of the biliary tract, verifying clearance of bile duct stones, bile duct ischemia evaluation after liver transplantation, hemobilia evaluation, removal of a bile duct foreign body, and evaluation of bile duct involvement in the presence of an ampullary adenoma.3,14,15,20,26,27
 

 

Risks and complications

Figure 5: Intraductal EHL: The EHL probe is located near the stone and the lithotripsy is performed. The bilary duct needs to be immersed with water to increase electric wave delivery and to protect the duct wall from injury.
In general, complications from cholangioscopy systems are similar to traditional ERCP. These complications can range from relatively mild to potentially life-threatening sequelae including: cholangitis, bacteremia, abdominal pain, pancreatitis, hypotension, nausea, liver abscesses, radiculopathy, bile duct drilling (from the guide-wire), clinically insignificant amylase and lipase elevation, and systemic inflammatory response syndrome.24 A large retrospective study evaluated whether ERCP with cholangiopancreatoscopy was associated with higher rates of complication than ERCP alone. A total of 4,214 ERCPs were included, of which 402 ERCPs with cholangiopancreatoscopy were analyzed. Adverse event rates for the ERCP alone group and ERCP with cholangiopancreatoscopy were 2.9% and 7.0%, respectively, with an odds ratio of 2.5. This study revealed a significantly higher rate of cholangitis, which the authors proposed was due to the saline irrigation needed for visualization during the procedure.28 Duodenal perforation appears to be rare and was treated conservatively.14,29

Conclusions

Direct visualization of the biliary and pancreatic ductal system with fiber-optic and now digital-based platforms have greatly expanded the diagnostic and therapeutic capabilities available to gastroenterologists in the diagnosis and management of biliary and pancreatic disorders. The digital single-operator cholangiopancreatascope system offers greater diagnostic yield of pancreaticobiliary disorders over conventional diagnostic sampling techniques. In addition, direct visualization has expanded our therapeutic ability in complex stone disease allowing laser-based therapies that are not available with traditional fluoroscopic based techniques. Cholangiopancreatoscopic techniques and indications are rapidly expanding and will continue to expand the diagnostic and therapeutic armamentarium available to gastroenterologists.

Dr. Sonnier is a general gastroenterology fellow, division of gastroenterology, University of South Alabama. Dr. Mizrahi is director of advanced endoscopy, division of gastroenterology, University of South Alabama. Dr. Pleskow, is clinical chief, department of gastroenterology, Beth Israel Deaconess Medical Center, and associate professor of medicine, Harvard Medical School, Boston. Dr. Sonnier and Dr. Mizrahi have no conflicts of interest. Dr. Pleskow serves as a consultant to Boston Scientific.

References

1. Cohen S., et al. Gastrointest Endosc. 2002;56:803–9

2. Lee J.G., et al. Am J Gastroenterol. 1995;90:722-6.

3. De Bellis M., et al. Gastrointest Endosc. 2003;58:176-82

4. Fritcher E.G., et al. Gastroenterology. 2009;136:2180-6.

5. Rosch T., et al. Gastrointest Endosc. 2004;60:390-6.

6. Byrne M.F., et al. Endoscopy. 2004;36:715-9.

7. DeWitt J., et al. Gastrointest Endosc. 2006;64:325-33.

8. Rosch W., Endoscopy. 1976;8:172-5.

9. Takekoshi T., Takagi K. Gastrointest Endosc. 1975;17:678-83.

10. Chen Y.K. Gastrointest Endosc 2007;65:303-11.

11. Navaneethan U., et al. Gastrointest Endosc 2016;84:649-55.

12. Navaneethan U., et al. Gastrointest Endosc 2015;82: 608-14.

13. Chen Y.K., Pleskow DK. Gastrointest Endosc. 2007;65:832-41.

14. Draganov P.V., et al. Gastrointest Endosc. 2011;73:971-9.

15. Ramchandani M., et al. Gastrointest Endosc. 2011;74:511-9.

16. Chen Y.K., et al. Gastrointest Endosc. 2011;74:805-14.

17. Draganov P.V., et al. Gastrointest Endosc. 2012;75:347-53.

18. Classen M., et al. Endoscopy 1988;20:21-6.

19. Parsi M.A., et al. Gastrointest Endosc 2008;67:AB102.

20. Fishman D.S., et al. World J Gastroenterol. 2009;15:1353-8.

21. Maydeo A., et al. Gastrointest Endosc. 2011;74:1308-14.

22. Yamao K., et al. Gastrointest Endosc 2003;57:205-9.

23. Hara T., et al. Gastroenterology 2002;122:34-43.

24. Rösch T., et al. Endoscopy. 2002;34:765–71.

25. Bekkali N.L., et al. Pancreas. 2017;46:528-30.

26. Adwan H., et al. Dig Endosc. 2011;23:199-200.

27. Ransibrahmanakul K., et al. Clin Gastroenterol Hepatol. 2010;8:e9.

28. Pereira P., et al. J Gastrointestin Liver Dis, June 2017;Vol. 26(No 2):165-70.

29. Kawakubo K., et al. Endoscopy 2011;43:E241-2.

Publications
Sections

 

Introduction

Direct visualization of the biliary ductal system is quickly gaining importance among gastroenterologists. Since the inception of cholangioscopy in the 1970s, the technology has progressed, allowing for ease of use, better visualization, and a growing number of indications. Conventional endoscopic retrograde cholangiopancreatography (ERCP) is successful for removal of bile duct stones (with success rates over 90%);1 however, its use in the evaluation of potential biliary neoplasia has been somewhat disappointing. The diagnostic yield of ERCP-guided biliary brushings can range from 30% to 40%.2-4 An alternative to ERCP-guided biliary brushings for biliary strictures is endoscopic ultrasound (EUS)-directed fine needle aspiration (FNA), but the reported sensitivity remains poor, ranging from 43% to 77% with negative predictive values of less than 30%.5-7 These results leave much to be desired for diagnostic yield.

Dr. William Preston Sonnier
The newest method of evaluating pancreaticobiliary pathology is with direct visualization using cholangioscopy. The advantages of this modality include the ability to obtain direct visualization as well as targeted biopsies of suspicious lesions. The first fiberoptic cholangioscope was introduced in 1965 and the first use of peroral cholangioscopy was reported in in the mid 1970s.8,9 Early models were limited by their delicacy, relative immmobility, lack of dedicated irrigation channel, and need for two endoscopists using a “mother baby” design. Fiberoptic single-operator cholangiopancreatoscopy (FSOCP) was first introduced in 2006 by Boston Scientific (Marlborough, MA).10 It was designed to address the previously stated shortcomings of the first-generation cholangioscopy devices. Since its introduction, it has gained worldwide popularity in the diagnosis and management of pancreaticobiliary pathology and complex biliary stones.

Dr. Meir Mizrahi
The initial model employed a reusable fiber optic optical probe, a disposable cholangioscope access and delivery catheter, and disposable small-caliber biopsy forceps. The components can be introduced through a duodenoscope that has a minimum working channel diameter of 3.4 mm. The original FSOCP catheter is attached to the duodenoscope by a silastic belt just below the operating channel, allowing for single operator use. The access and delivery catheter has an outer diameter of 10 F and three separate ports: an optical port, two dedicated 0.6-mm irrigation channels, and a 1.2-mm accessory channel that accepts various accessories including the small-caliber biopsy forceps, electrohydraulic lithotripsy (EHL) fibers, or a holmium laser probe. The catheter has fourway tip deflection. The fiberoptic probe does have limitations, including its limited field of view, fragility of the fiber, and need for adjustment of the lens focus. Because of these limitations, a digital single-operator cholangioscope (DSOCP) was developed and introduced in 2014 (Boston Scientific, Marlborough, MA). In the DSOCP system, the light is generated by two independent light-emitting diodes and a complementary metal-oxide semiconductor digital camera chip. Improvements included a wider 120-degree field of view, dedicated irrigation and aspiration channels/connections, suction channel, and redesigned accessory channel. The cholangioscope is entirely disposable. The processor receives video signals from the catheter, processes the signals and outputs video images to an attached monitor. The newer digital-based platform has shown promising results, including higher diagnostic yield and shorter ERCP completion time when compared with similarly performed procedures using the fiberoptic-based platform.11

Clinical indications

Dr. Douglas K. Pleskow
Direct visualization and biopsy of indeterminate biliary strictures has resulted in greatly improved diagnostic accuracy and collection of adequate tissue (Figures. 1,2). In a recent systematic review, the pooled sensitivity and specificity of cholangioscopy-guided biopsies in the diagnosis of malignant biliary strictures was 61% (95% confidence interval, 55%-65%) and 98% (95% CI, 96%-99%), respectively. Direct comparison of small-caliber direct biopsies with standard brushings and biopsies showed small-caliber direct biopsies having a sensitivity of 76.5% versus 5.8% and 29% with standard brushes and biopsies, respectively.12 The pooled sensitivity and specificity of six studies using cholangioscopy with targeted biopsies in the diagnosis of cholangiocarcinoma was 66.2% and 97.0%, respectively.12 Studies have shown that small-caliber forceps obtains tissue adequate for pathologic evaluation in 82%-97% of biopsy samples retrieved.13-17 Three prospective trials have evaluated the diagnostic accuracy of small-caliber forceps for indeterminate biliary lesions. The accuracy ranged from 72% to 85% with a sensitivity of 49%-82%, specificity of 82%-100%, positive predictive value of 100%, and negative predictive value of 69%-100%.15-17 The improved diagnostic accuracy of cholangioscopy for indeterminate biliary strictures stems from its direct visualization ability. Traditional sampling techniques (cytology brushings and fluoroscopically guided biopsies) are plagued by low sensitivity and negative predictive value caused by a relatively high false-positive rate.

DSOCP appears to have improved accuracy over fiberoptic equipment. In a recent multicenter observational study in patients undergoing digital cholangioscopy, the guided biopsies resulted in adequate tissue for histologic evaluation in 98% of patients. In addition, the sensitivity and specificity of digital cholangioscope-guided biopsies for diagnosis of malignancy was 85% and 100%, respectively.11

Dr. Sonnier, Dr. Mizrahi, and Dr. Pleskow
Figure 1: Intraductal lesion seen after stone clearance by EHL.
Conventional ERCP is successful in most cases of biliary stone extraction but, in 5%-10% of cases, stones can be difficult to remove because of size, location above strictures, or adherence to the bile duct wall18 (Figure 3). In addition, lithotripsy with standard fluoroscopic guidance can cause stone fragments to get lost. In one study, 29% of ERCP-lost gallstones were diagnosed by post-hoc cholangioscopy.19 A number of studies have documented a high success rate of FSOCP- or DSOCP-guided lithotripsy, ranging from 90% to 100% (13,14,16,20,21). In addition cholangioscopy can circumvent the need for mechanical lithotripsy. EHL is used for the majority of cases, but use of a holium laser has also been described.20,21 The dedicated irrigation channels on the FSOCP/DSOCP system give the ability to continuously fill the biliary system with fluid, which is required for EHL (Figures 4,5).

Dr. Sonnier, Dr. Mizrahi, and Dr. Pleskow
Figure 2: Intraductal lesion seen in direct visualization, intraductal endoscopic ultrasound confirmed the presence of varice.
Diagnostic pancreatoscopy has advantages in the diagnosis and future management of malignancies and intraductal papillary mucinous neoplasms (IPMNs). In addition, pancreatic duct stones can easily be managed with digital pancreatoscopy and lithotripsy (EHL or laser lithotripsy). A study that included 115 patients that were followed for at least 2 years showed that pancreatoscopy was able to diagnose 63% of pancreatic cancers, 80% of benign strictures, and 95% of intraductal papillary mucinous neoplasms based on visual appearances. The authors were able to discern neoplasia based on visual findings, including coarse or granular mucosa, protrusion, papillary tumor, and tumor vessel.22 In a similar study, patients with confirmed intraductal papilliary mucinous neoplasms (IPMN) underwent peroral pancreatoscopy and/or intraductal ultrasound preoperatively. The detected protruding lesions were classified into five groups: granular mucosa, fish-egg with or without vascular images, villous type, and vegetative type. The diagnostic accuracy of peroral pancreatoscopy in differentiating benign IPMN from malignant ones was 88% with a sensitivity and specificity of 100% and 71% in the main duct type, respectively, and sensitivities and specificities of 43% and 100% of branch type, respectively.23

Figure 3: Large intraductal stone noted on DSOCP.
DSOCP also has therapeutic implications for other pancreatic diseases. Pancreatic duct obstruction can be caused by stones and strictures. A large multicenter study of 1,000 patients with chronic pancreatitis revealed obstruction of the main pancreatic duct (MPD) in 50%; with 32% being caused by strictures and stones, while 18% were due solely to stones.24 Currently accepted treatments for pancreaticolithiasis include extracorporeal shock wave lithotripsy, ERCP with stone clearance, and stenting or surgery (pancreaticojejunostomy) but these techniques have limitations and can incur morbidity.

Figure 4: Demonstration of EHL probe. The setting as noted should be 100 watts and 20 shots per cycle.
DSOCP has recently been evaluated as an alternative technique in treating MPD stones. In a recent study, Bekkali et al reviewed their 3-year experience of digital pancreatoscopy and EHL for pancreatic duct stones. Of the pancreatoscopy procedures performed, 7% were for pancreatic stones. All the patients had painful chronic pancreatitis, radiographic evidence of a dilated pancreatic duct, and MPD stone disease. Stone fragmentation and pancreatic duct decompression were achieved in 83% without complications. Two patients required two EHL procedures to achieve clearance. In the single patient with failed clearance, pancreatoscopy revealed the stone to be in adjacent parenchyma and not in the pancreatic duct. All patients with successful pancreatoscopy and EHL had pain relief and marked improvement during follow up.25

Other less common diagnostic indications for DSOCP include evaluation of cystic lesions of the biliary tract, verifying clearance of bile duct stones, bile duct ischemia evaluation after liver transplantation, hemobilia evaluation, removal of a bile duct foreign body, and evaluation of bile duct involvement in the presence of an ampullary adenoma.3,14,15,20,26,27
 

 

Risks and complications

Figure 5: Intraductal EHL: The EHL probe is located near the stone and the lithotripsy is performed. The bilary duct needs to be immersed with water to increase electric wave delivery and to protect the duct wall from injury.
In general, complications from cholangioscopy systems are similar to traditional ERCP. These complications can range from relatively mild to potentially life-threatening sequelae including: cholangitis, bacteremia, abdominal pain, pancreatitis, hypotension, nausea, liver abscesses, radiculopathy, bile duct drilling (from the guide-wire), clinically insignificant amylase and lipase elevation, and systemic inflammatory response syndrome.24 A large retrospective study evaluated whether ERCP with cholangiopancreatoscopy was associated with higher rates of complication than ERCP alone. A total of 4,214 ERCPs were included, of which 402 ERCPs with cholangiopancreatoscopy were analyzed. Adverse event rates for the ERCP alone group and ERCP with cholangiopancreatoscopy were 2.9% and 7.0%, respectively, with an odds ratio of 2.5. This study revealed a significantly higher rate of cholangitis, which the authors proposed was due to the saline irrigation needed for visualization during the procedure.28 Duodenal perforation appears to be rare and was treated conservatively.14,29

Conclusions

Direct visualization of the biliary and pancreatic ductal system with fiber-optic and now digital-based platforms have greatly expanded the diagnostic and therapeutic capabilities available to gastroenterologists in the diagnosis and management of biliary and pancreatic disorders. The digital single-operator cholangiopancreatascope system offers greater diagnostic yield of pancreaticobiliary disorders over conventional diagnostic sampling techniques. In addition, direct visualization has expanded our therapeutic ability in complex stone disease allowing laser-based therapies that are not available with traditional fluoroscopic based techniques. Cholangiopancreatoscopic techniques and indications are rapidly expanding and will continue to expand the diagnostic and therapeutic armamentarium available to gastroenterologists.

Dr. Sonnier is a general gastroenterology fellow, division of gastroenterology, University of South Alabama. Dr. Mizrahi is director of advanced endoscopy, division of gastroenterology, University of South Alabama. Dr. Pleskow, is clinical chief, department of gastroenterology, Beth Israel Deaconess Medical Center, and associate professor of medicine, Harvard Medical School, Boston. Dr. Sonnier and Dr. Mizrahi have no conflicts of interest. Dr. Pleskow serves as a consultant to Boston Scientific.

References

1. Cohen S., et al. Gastrointest Endosc. 2002;56:803–9

2. Lee J.G., et al. Am J Gastroenterol. 1995;90:722-6.

3. De Bellis M., et al. Gastrointest Endosc. 2003;58:176-82

4. Fritcher E.G., et al. Gastroenterology. 2009;136:2180-6.

5. Rosch T., et al. Gastrointest Endosc. 2004;60:390-6.

6. Byrne M.F., et al. Endoscopy. 2004;36:715-9.

7. DeWitt J., et al. Gastrointest Endosc. 2006;64:325-33.

8. Rosch W., Endoscopy. 1976;8:172-5.

9. Takekoshi T., Takagi K. Gastrointest Endosc. 1975;17:678-83.

10. Chen Y.K. Gastrointest Endosc 2007;65:303-11.

11. Navaneethan U., et al. Gastrointest Endosc 2016;84:649-55.

12. Navaneethan U., et al. Gastrointest Endosc 2015;82: 608-14.

13. Chen Y.K., Pleskow DK. Gastrointest Endosc. 2007;65:832-41.

14. Draganov P.V., et al. Gastrointest Endosc. 2011;73:971-9.

15. Ramchandani M., et al. Gastrointest Endosc. 2011;74:511-9.

16. Chen Y.K., et al. Gastrointest Endosc. 2011;74:805-14.

17. Draganov P.V., et al. Gastrointest Endosc. 2012;75:347-53.

18. Classen M., et al. Endoscopy 1988;20:21-6.

19. Parsi M.A., et al. Gastrointest Endosc 2008;67:AB102.

20. Fishman D.S., et al. World J Gastroenterol. 2009;15:1353-8.

21. Maydeo A., et al. Gastrointest Endosc. 2011;74:1308-14.

22. Yamao K., et al. Gastrointest Endosc 2003;57:205-9.

23. Hara T., et al. Gastroenterology 2002;122:34-43.

24. Rösch T., et al. Endoscopy. 2002;34:765–71.

25. Bekkali N.L., et al. Pancreas. 2017;46:528-30.

26. Adwan H., et al. Dig Endosc. 2011;23:199-200.

27. Ransibrahmanakul K., et al. Clin Gastroenterol Hepatol. 2010;8:e9.

28. Pereira P., et al. J Gastrointestin Liver Dis, June 2017;Vol. 26(No 2):165-70.

29. Kawakubo K., et al. Endoscopy 2011;43:E241-2.

 

Introduction

Direct visualization of the biliary ductal system is quickly gaining importance among gastroenterologists. Since the inception of cholangioscopy in the 1970s, the technology has progressed, allowing for ease of use, better visualization, and a growing number of indications. Conventional endoscopic retrograde cholangiopancreatography (ERCP) is successful for removal of bile duct stones (with success rates over 90%);1 however, its use in the evaluation of potential biliary neoplasia has been somewhat disappointing. The diagnostic yield of ERCP-guided biliary brushings can range from 30% to 40%.2-4 An alternative to ERCP-guided biliary brushings for biliary strictures is endoscopic ultrasound (EUS)-directed fine needle aspiration (FNA), but the reported sensitivity remains poor, ranging from 43% to 77% with negative predictive values of less than 30%.5-7 These results leave much to be desired for diagnostic yield.

Dr. William Preston Sonnier
The newest method of evaluating pancreaticobiliary pathology is with direct visualization using cholangioscopy. The advantages of this modality include the ability to obtain direct visualization as well as targeted biopsies of suspicious lesions. The first fiberoptic cholangioscope was introduced in 1965 and the first use of peroral cholangioscopy was reported in in the mid 1970s.8,9 Early models were limited by their delicacy, relative immmobility, lack of dedicated irrigation channel, and need for two endoscopists using a “mother baby” design. Fiberoptic single-operator cholangiopancreatoscopy (FSOCP) was first introduced in 2006 by Boston Scientific (Marlborough, MA).10 It was designed to address the previously stated shortcomings of the first-generation cholangioscopy devices. Since its introduction, it has gained worldwide popularity in the diagnosis and management of pancreaticobiliary pathology and complex biliary stones.

Dr. Meir Mizrahi
The initial model employed a reusable fiber optic optical probe, a disposable cholangioscope access and delivery catheter, and disposable small-caliber biopsy forceps. The components can be introduced through a duodenoscope that has a minimum working channel diameter of 3.4 mm. The original FSOCP catheter is attached to the duodenoscope by a silastic belt just below the operating channel, allowing for single operator use. The access and delivery catheter has an outer diameter of 10 F and three separate ports: an optical port, two dedicated 0.6-mm irrigation channels, and a 1.2-mm accessory channel that accepts various accessories including the small-caliber biopsy forceps, electrohydraulic lithotripsy (EHL) fibers, or a holmium laser probe. The catheter has fourway tip deflection. The fiberoptic probe does have limitations, including its limited field of view, fragility of the fiber, and need for adjustment of the lens focus. Because of these limitations, a digital single-operator cholangioscope (DSOCP) was developed and introduced in 2014 (Boston Scientific, Marlborough, MA). In the DSOCP system, the light is generated by two independent light-emitting diodes and a complementary metal-oxide semiconductor digital camera chip. Improvements included a wider 120-degree field of view, dedicated irrigation and aspiration channels/connections, suction channel, and redesigned accessory channel. The cholangioscope is entirely disposable. The processor receives video signals from the catheter, processes the signals and outputs video images to an attached monitor. The newer digital-based platform has shown promising results, including higher diagnostic yield and shorter ERCP completion time when compared with similarly performed procedures using the fiberoptic-based platform.11

Clinical indications

Dr. Douglas K. Pleskow
Direct visualization and biopsy of indeterminate biliary strictures has resulted in greatly improved diagnostic accuracy and collection of adequate tissue (Figures. 1,2). In a recent systematic review, the pooled sensitivity and specificity of cholangioscopy-guided biopsies in the diagnosis of malignant biliary strictures was 61% (95% confidence interval, 55%-65%) and 98% (95% CI, 96%-99%), respectively. Direct comparison of small-caliber direct biopsies with standard brushings and biopsies showed small-caliber direct biopsies having a sensitivity of 76.5% versus 5.8% and 29% with standard brushes and biopsies, respectively.12 The pooled sensitivity and specificity of six studies using cholangioscopy with targeted biopsies in the diagnosis of cholangiocarcinoma was 66.2% and 97.0%, respectively.12 Studies have shown that small-caliber forceps obtains tissue adequate for pathologic evaluation in 82%-97% of biopsy samples retrieved.13-17 Three prospective trials have evaluated the diagnostic accuracy of small-caliber forceps for indeterminate biliary lesions. The accuracy ranged from 72% to 85% with a sensitivity of 49%-82%, specificity of 82%-100%, positive predictive value of 100%, and negative predictive value of 69%-100%.15-17 The improved diagnostic accuracy of cholangioscopy for indeterminate biliary strictures stems from its direct visualization ability. Traditional sampling techniques (cytology brushings and fluoroscopically guided biopsies) are plagued by low sensitivity and negative predictive value caused by a relatively high false-positive rate.

DSOCP appears to have improved accuracy over fiberoptic equipment. In a recent multicenter observational study in patients undergoing digital cholangioscopy, the guided biopsies resulted in adequate tissue for histologic evaluation in 98% of patients. In addition, the sensitivity and specificity of digital cholangioscope-guided biopsies for diagnosis of malignancy was 85% and 100%, respectively.11

Dr. Sonnier, Dr. Mizrahi, and Dr. Pleskow
Figure 1: Intraductal lesion seen after stone clearance by EHL.
Conventional ERCP is successful in most cases of biliary stone extraction but, in 5%-10% of cases, stones can be difficult to remove because of size, location above strictures, or adherence to the bile duct wall18 (Figure 3). In addition, lithotripsy with standard fluoroscopic guidance can cause stone fragments to get lost. In one study, 29% of ERCP-lost gallstones were diagnosed by post-hoc cholangioscopy.19 A number of studies have documented a high success rate of FSOCP- or DSOCP-guided lithotripsy, ranging from 90% to 100% (13,14,16,20,21). In addition cholangioscopy can circumvent the need for mechanical lithotripsy. EHL is used for the majority of cases, but use of a holium laser has also been described.20,21 The dedicated irrigation channels on the FSOCP/DSOCP system give the ability to continuously fill the biliary system with fluid, which is required for EHL (Figures 4,5).

Dr. Sonnier, Dr. Mizrahi, and Dr. Pleskow
Figure 2: Intraductal lesion seen in direct visualization, intraductal endoscopic ultrasound confirmed the presence of varice.
Diagnostic pancreatoscopy has advantages in the diagnosis and future management of malignancies and intraductal papillary mucinous neoplasms (IPMNs). In addition, pancreatic duct stones can easily be managed with digital pancreatoscopy and lithotripsy (EHL or laser lithotripsy). A study that included 115 patients that were followed for at least 2 years showed that pancreatoscopy was able to diagnose 63% of pancreatic cancers, 80% of benign strictures, and 95% of intraductal papillary mucinous neoplasms based on visual appearances. The authors were able to discern neoplasia based on visual findings, including coarse or granular mucosa, protrusion, papillary tumor, and tumor vessel.22 In a similar study, patients with confirmed intraductal papilliary mucinous neoplasms (IPMN) underwent peroral pancreatoscopy and/or intraductal ultrasound preoperatively. The detected protruding lesions were classified into five groups: granular mucosa, fish-egg with or without vascular images, villous type, and vegetative type. The diagnostic accuracy of peroral pancreatoscopy in differentiating benign IPMN from malignant ones was 88% with a sensitivity and specificity of 100% and 71% in the main duct type, respectively, and sensitivities and specificities of 43% and 100% of branch type, respectively.23

Figure 3: Large intraductal stone noted on DSOCP.
DSOCP also has therapeutic implications for other pancreatic diseases. Pancreatic duct obstruction can be caused by stones and strictures. A large multicenter study of 1,000 patients with chronic pancreatitis revealed obstruction of the main pancreatic duct (MPD) in 50%; with 32% being caused by strictures and stones, while 18% were due solely to stones.24 Currently accepted treatments for pancreaticolithiasis include extracorporeal shock wave lithotripsy, ERCP with stone clearance, and stenting or surgery (pancreaticojejunostomy) but these techniques have limitations and can incur morbidity.

Figure 4: Demonstration of EHL probe. The setting as noted should be 100 watts and 20 shots per cycle.
DSOCP has recently been evaluated as an alternative technique in treating MPD stones. In a recent study, Bekkali et al reviewed their 3-year experience of digital pancreatoscopy and EHL for pancreatic duct stones. Of the pancreatoscopy procedures performed, 7% were for pancreatic stones. All the patients had painful chronic pancreatitis, radiographic evidence of a dilated pancreatic duct, and MPD stone disease. Stone fragmentation and pancreatic duct decompression were achieved in 83% without complications. Two patients required two EHL procedures to achieve clearance. In the single patient with failed clearance, pancreatoscopy revealed the stone to be in adjacent parenchyma and not in the pancreatic duct. All patients with successful pancreatoscopy and EHL had pain relief and marked improvement during follow up.25

Other less common diagnostic indications for DSOCP include evaluation of cystic lesions of the biliary tract, verifying clearance of bile duct stones, bile duct ischemia evaluation after liver transplantation, hemobilia evaluation, removal of a bile duct foreign body, and evaluation of bile duct involvement in the presence of an ampullary adenoma.3,14,15,20,26,27
 

 

Risks and complications

Figure 5: Intraductal EHL: The EHL probe is located near the stone and the lithotripsy is performed. The bilary duct needs to be immersed with water to increase electric wave delivery and to protect the duct wall from injury.
In general, complications from cholangioscopy systems are similar to traditional ERCP. These complications can range from relatively mild to potentially life-threatening sequelae including: cholangitis, bacteremia, abdominal pain, pancreatitis, hypotension, nausea, liver abscesses, radiculopathy, bile duct drilling (from the guide-wire), clinically insignificant amylase and lipase elevation, and systemic inflammatory response syndrome.24 A large retrospective study evaluated whether ERCP with cholangiopancreatoscopy was associated with higher rates of complication than ERCP alone. A total of 4,214 ERCPs were included, of which 402 ERCPs with cholangiopancreatoscopy were analyzed. Adverse event rates for the ERCP alone group and ERCP with cholangiopancreatoscopy were 2.9% and 7.0%, respectively, with an odds ratio of 2.5. This study revealed a significantly higher rate of cholangitis, which the authors proposed was due to the saline irrigation needed for visualization during the procedure.28 Duodenal perforation appears to be rare and was treated conservatively.14,29

Conclusions

Direct visualization of the biliary and pancreatic ductal system with fiber-optic and now digital-based platforms have greatly expanded the diagnostic and therapeutic capabilities available to gastroenterologists in the diagnosis and management of biliary and pancreatic disorders. The digital single-operator cholangiopancreatascope system offers greater diagnostic yield of pancreaticobiliary disorders over conventional diagnostic sampling techniques. In addition, direct visualization has expanded our therapeutic ability in complex stone disease allowing laser-based therapies that are not available with traditional fluoroscopic based techniques. Cholangiopancreatoscopic techniques and indications are rapidly expanding and will continue to expand the diagnostic and therapeutic armamentarium available to gastroenterologists.

Dr. Sonnier is a general gastroenterology fellow, division of gastroenterology, University of South Alabama. Dr. Mizrahi is director of advanced endoscopy, division of gastroenterology, University of South Alabama. Dr. Pleskow, is clinical chief, department of gastroenterology, Beth Israel Deaconess Medical Center, and associate professor of medicine, Harvard Medical School, Boston. Dr. Sonnier and Dr. Mizrahi have no conflicts of interest. Dr. Pleskow serves as a consultant to Boston Scientific.

References

1. Cohen S., et al. Gastrointest Endosc. 2002;56:803–9

2. Lee J.G., et al. Am J Gastroenterol. 1995;90:722-6.

3. De Bellis M., et al. Gastrointest Endosc. 2003;58:176-82

4. Fritcher E.G., et al. Gastroenterology. 2009;136:2180-6.

5. Rosch T., et al. Gastrointest Endosc. 2004;60:390-6.

6. Byrne M.F., et al. Endoscopy. 2004;36:715-9.

7. DeWitt J., et al. Gastrointest Endosc. 2006;64:325-33.

8. Rosch W., Endoscopy. 1976;8:172-5.

9. Takekoshi T., Takagi K. Gastrointest Endosc. 1975;17:678-83.

10. Chen Y.K. Gastrointest Endosc 2007;65:303-11.

11. Navaneethan U., et al. Gastrointest Endosc 2016;84:649-55.

12. Navaneethan U., et al. Gastrointest Endosc 2015;82: 608-14.

13. Chen Y.K., Pleskow DK. Gastrointest Endosc. 2007;65:832-41.

14. Draganov P.V., et al. Gastrointest Endosc. 2011;73:971-9.

15. Ramchandani M., et al. Gastrointest Endosc. 2011;74:511-9.

16. Chen Y.K., et al. Gastrointest Endosc. 2011;74:805-14.

17. Draganov P.V., et al. Gastrointest Endosc. 2012;75:347-53.

18. Classen M., et al. Endoscopy 1988;20:21-6.

19. Parsi M.A., et al. Gastrointest Endosc 2008;67:AB102.

20. Fishman D.S., et al. World J Gastroenterol. 2009;15:1353-8.

21. Maydeo A., et al. Gastrointest Endosc. 2011;74:1308-14.

22. Yamao K., et al. Gastrointest Endosc 2003;57:205-9.

23. Hara T., et al. Gastroenterology 2002;122:34-43.

24. Rösch T., et al. Endoscopy. 2002;34:765–71.

25. Bekkali N.L., et al. Pancreas. 2017;46:528-30.

26. Adwan H., et al. Dig Endosc. 2011;23:199-200.

27. Ransibrahmanakul K., et al. Clin Gastroenterol Hepatol. 2010;8:e9.

28. Pereira P., et al. J Gastrointestin Liver Dis, June 2017;Vol. 26(No 2):165-70.

29. Kawakubo K., et al. Endoscopy 2011;43:E241-2.

Publications
Publications
Article Type
Sections
Disallow All Ads
Content Gating
No Gating (article Unlocked/Free)
Alternative CME
Disqus Comments
Default

An Unusual Cause of Recurrent Severe Abdominal Colic

Article Type
Changed

 

AGA Institute
Figure E
The correct answer is B. The lead levels in serum and urine were tested (517 mcg/L, 0-400 mcg/L; 131.7 mcg/L, 0-70.38 mcg/L). A diagnosis of lead poisoning was made. Three days after chelation treatment, his symptoms disappeared and did not recur in the follow-up.

We carefully reviewed the patient’s history and found that he had been using jineijin, a traditional Chinese medicine (TCM) drug, which is made with dried endothelium corneum gigeriae galli (Figure E), at about 500 g/month and squama mantis (a TCM drug, at less than 5 g/month) as dietary supplements for 3 years.

AGA Institute
Figure F
The level of lead in ground jineijin (Figure F, the drug the patients consumed is mainly processed by mixing ground jineijin and honey; Figure G, the deposit left after the elution of honey in Figure F is ground jineijin) and squama mantis was measured with inductively coupled plasma optical emission spectrometry, which proved to be 3,389 mg/kg, much higher than the maximal limit allowed for drinking water (less than 0.01 mg/kg). It is estimated that the patient’s daily lead intake from ground jineijin and squama mantis approximated 50 mg/day (acceptable limit being 100-300 mcg/day)1 in the past 3 years.

AGA Institute
Figure G
Jineijin has traditionally been used in China to alleviate nausea and vomiting.2 With the rapid development of industry, heavy metal pollution of water and soil has been a widespread problem.3 Heavy metal enrichment may appear in poultry exposed to environmental population. Therefore, the lead content of jineijin obtained from poultry with high levels of lead exposure can easily exceed maximum acceptable limits. In this patient, long-term high-dosage consumption of jineijin may have been the source of lead exposure.
 

Acknowledgments

We thank Linshen Xie, MD, department of environmental health and occupational diseases, No. 4 West China Teaching Hospital, Sichuan University, for offering some clinical data. We thank the patient for giving permission to share his information.

References

1. National Research Council (US). Safe Drinking Water Committee. Drinking water and health. National Academy Press. Washington, D.C. 1977;1:309.

2. State Administration of Traditional Chinese Medicine. Advanced Textbook on Traditional Chinese Medicine and Pharmacology. New World Press, Beijing. 1995. (vol. 2).

3. Hui Hu, Q.J., Kavan, P. A study of heavy metal pollution in China: Current status, pollution-control policies and countermeasures. Sustainability. 2014;6:5820-38.
 

This article has an accompanying continuing medical education activity, also eligible for MOC credit, Learning objective: Upon completion of this examination, successful learners will be able to identify the features of lead poisoning.
 

Publications
Sections

 

AGA Institute
Figure E
The correct answer is B. The lead levels in serum and urine were tested (517 mcg/L, 0-400 mcg/L; 131.7 mcg/L, 0-70.38 mcg/L). A diagnosis of lead poisoning was made. Three days after chelation treatment, his symptoms disappeared and did not recur in the follow-up.

We carefully reviewed the patient’s history and found that he had been using jineijin, a traditional Chinese medicine (TCM) drug, which is made with dried endothelium corneum gigeriae galli (Figure E), at about 500 g/month and squama mantis (a TCM drug, at less than 5 g/month) as dietary supplements for 3 years.

AGA Institute
Figure F
The level of lead in ground jineijin (Figure F, the drug the patients consumed is mainly processed by mixing ground jineijin and honey; Figure G, the deposit left after the elution of honey in Figure F is ground jineijin) and squama mantis was measured with inductively coupled plasma optical emission spectrometry, which proved to be 3,389 mg/kg, much higher than the maximal limit allowed for drinking water (less than 0.01 mg/kg). It is estimated that the patient’s daily lead intake from ground jineijin and squama mantis approximated 50 mg/day (acceptable limit being 100-300 mcg/day)1 in the past 3 years.

AGA Institute
Figure G
Jineijin has traditionally been used in China to alleviate nausea and vomiting.2 With the rapid development of industry, heavy metal pollution of water and soil has been a widespread problem.3 Heavy metal enrichment may appear in poultry exposed to environmental population. Therefore, the lead content of jineijin obtained from poultry with high levels of lead exposure can easily exceed maximum acceptable limits. In this patient, long-term high-dosage consumption of jineijin may have been the source of lead exposure.
 

Acknowledgments

We thank Linshen Xie, MD, department of environmental health and occupational diseases, No. 4 West China Teaching Hospital, Sichuan University, for offering some clinical data. We thank the patient for giving permission to share his information.

References

1. National Research Council (US). Safe Drinking Water Committee. Drinking water and health. National Academy Press. Washington, D.C. 1977;1:309.

2. State Administration of Traditional Chinese Medicine. Advanced Textbook on Traditional Chinese Medicine and Pharmacology. New World Press, Beijing. 1995. (vol. 2).

3. Hui Hu, Q.J., Kavan, P. A study of heavy metal pollution in China: Current status, pollution-control policies and countermeasures. Sustainability. 2014;6:5820-38.
 

This article has an accompanying continuing medical education activity, also eligible for MOC credit, Learning objective: Upon completion of this examination, successful learners will be able to identify the features of lead poisoning.
 

 

AGA Institute
Figure E
The correct answer is B. The lead levels in serum and urine were tested (517 mcg/L, 0-400 mcg/L; 131.7 mcg/L, 0-70.38 mcg/L). A diagnosis of lead poisoning was made. Three days after chelation treatment, his symptoms disappeared and did not recur in the follow-up.

We carefully reviewed the patient’s history and found that he had been using jineijin, a traditional Chinese medicine (TCM) drug, which is made with dried endothelium corneum gigeriae galli (Figure E), at about 500 g/month and squama mantis (a TCM drug, at less than 5 g/month) as dietary supplements for 3 years.

AGA Institute
Figure F
The level of lead in ground jineijin (Figure F, the drug the patients consumed is mainly processed by mixing ground jineijin and honey; Figure G, the deposit left after the elution of honey in Figure F is ground jineijin) and squama mantis was measured with inductively coupled plasma optical emission spectrometry, which proved to be 3,389 mg/kg, much higher than the maximal limit allowed for drinking water (less than 0.01 mg/kg). It is estimated that the patient’s daily lead intake from ground jineijin and squama mantis approximated 50 mg/day (acceptable limit being 100-300 mcg/day)1 in the past 3 years.

AGA Institute
Figure G
Jineijin has traditionally been used in China to alleviate nausea and vomiting.2 With the rapid development of industry, heavy metal pollution of water and soil has been a widespread problem.3 Heavy metal enrichment may appear in poultry exposed to environmental population. Therefore, the lead content of jineijin obtained from poultry with high levels of lead exposure can easily exceed maximum acceptable limits. In this patient, long-term high-dosage consumption of jineijin may have been the source of lead exposure.
 

Acknowledgments

We thank Linshen Xie, MD, department of environmental health and occupational diseases, No. 4 West China Teaching Hospital, Sichuan University, for offering some clinical data. We thank the patient for giving permission to share his information.

References

1. National Research Council (US). Safe Drinking Water Committee. Drinking water and health. National Academy Press. Washington, D.C. 1977;1:309.

2. State Administration of Traditional Chinese Medicine. Advanced Textbook on Traditional Chinese Medicine and Pharmacology. New World Press, Beijing. 1995. (vol. 2).

3. Hui Hu, Q.J., Kavan, P. A study of heavy metal pollution in China: Current status, pollution-control policies and countermeasures. Sustainability. 2014;6:5820-38.
 

This article has an accompanying continuing medical education activity, also eligible for MOC credit, Learning objective: Upon completion of this examination, successful learners will be able to identify the features of lead poisoning.
 

Publications
Publications
Article Type
Sections
Questionnaire Body

Published previously in Gastroenterology (2016;151:819-21)


AGA Institute
A 56-year-old man with severe colic, periumbilical pain, and constipation for eighteen months was referred to our hospital. He complained of unbearable pain that occurred on and off every 2-3 months. He did not have fever or hematochezia. Four weeks before he came to our hospital, he went to another local hospital, where gastroscopy and colonoscopy were performed and nothing abnormal was observed. However, the patient also had abdominal computed tomography angiography (CTA) and right ileocolic artery stenosis was highly suspected. Then, the patient received treatment for ischemic bowel disease and no improvement in his symptoms was reported.
AGA Institute
On admission to our hospital, the patient’s vital signs were normal. He had brown stains on his teeth. The chest examinations were normal. The abdominal examination revealed hypoactive bowel sounds and mild diffuse abdominal tenderness without rebound. Laboratory investigation showed hepatitis B infection (DNA level 5.78 × 105 copy/mL, and liver function within normal range), and mild anemia (hemoglobin concentration 103 g/L). The tests for serum iron, folate, and vitamin B12 levels all showed negative results.
AGA Institute
The urine and stool tests yielded normal results. Tests for autoimmune diseases showed negative results. Gastroscopy, colonoscopy, and abdominal CTA (Figure A) were repeated and yet again produced normal results. Magnetic resonance enterography showed parts of the small bowel walls thickening in the left upper abdomen (Figure B).
AGA Institute
Double-balloon endoscopy revealed patchy redness and congestion at two sites between 50 cm (Figure C) and 150 cm (Figure D) from the pylorus. Some time after the patient was admitted, his symptoms deteriorated so much so that he attempted suicide.

Dr. Deng, Dr. Hu, and Dr. Zhang are in the department of gastroenterology, West China Hospital, Sichuan University, Sichuan Province, China.

Disallow All Ads
Content Gating
No Gating (article Unlocked/Free)
Alternative CME
Disqus Comments
Default

News from AGA

Article Type
Changed

 

Advice on Achieving Work-Life Balance

Successfully maintaining a balance between your personal and professional lives is a difficult concept to grasp and practice to enforce. Is this thing called “work-life balance” within reach or just some elusive circumstance people talk about? The AGA Community Early Career Group was the hub for discussions on ways early-career gastroenterologists can modify their day-to-day approach to help prevent burnout.

We consolidated the advice and tips shared into a series of articles and resources to help students, trainees, and early career members get a little closer to balancing their work and professional lives. Here are some highlights:
 

Choose work-life “integration”

If your career and your personal life were a successful relationship, remember that it’s not always 50/50, and be sure to allow forgiveness and reparation when needed.

Maternity leave

When it comes to starting a family, think about your current training or career climate and how you can make it work. Be transparent with your supervisor so there aren’t any surprises, and plans can be made in advance to cover for your time away. Prepare to be flexible from the beginning.

Learn when to say “no”

Saying “yes” to too many things not only leads to overextending yourself beyond your capabilities, but you could also be losing time on what is important to you. Choose one night a week when you can work late – pack a snack, and give yourself a hard stop the rest of the week. Keep patient documentation as a daytime/work task.

Communication is key

When your partner or spouse is just as busy, it’s important to keep a joint calendar up to date and make plans far in advance. Also, create a routine: Try making time once a month to discuss calendars and anticipated events, face-to-face. When life throws a divot in your path, don’t lose sight of your priorities.

Make time for family and friends

Your career can take over as much of your life as you will allow. Making time for family and friends is rewarding and vacations, staycations, long weekends or even day trips can be great “resets.”
 

View the tip sheet and other work-life balance resources in the AGA Community Early Career Group library at http://community.gastro.org/WorkLife.
 

New Clinical Guidelines and Practice Updates

The latest AGA Clinical Practice Guideline, published in Gastroenterology, is on the role of therapeutic drug monitoring (TDM) in the management of IBD. It focuses on the application of TDM for biologic therapy, specifically anti-tumor necrosis factor-α (TNF) agents, and for thiopurines, and addresses questions on the risks and benefits of reactive TDM, routine proactive TDM, or no TDM in guiding treatment changes.

View the full guideline, technical review, and patient guide at www.gastro.org/guidelines.

In addition to guidelines, please check out the most recent Clinical Practice Updates (CPU) in Gastroenterology and Clinical Gastroenterology and Hepatology (CGH), which are often accompanied by a practice quiz from one of the authors, via the AGA Community. Visit http://community.gastro.org/guidelinecpu to test your knowledge. The most recent CPU, published in the September issue of CGH, focuses on GI side effects related to opioid medications.
 

Be Part of the Meeting to Transform IBD

If you treat patients with inflammatory bowel disease, conduct IBD research, or plan to pursue a career in IBD, join us for the inaugural Crohn’s & Colitis Congress™, taking place Jan. 18-20, 2018, in Las Vegas, NV. The Crohn’s & Colitis Foundation (formerly CCFA) and AGA have joined together to develop a must-attend program for the entire IBD care team. Expand your knowledge, network with your peers as well as IBD leaders across multiple disciplines, and get inspired to improve care for patients with Crohn’s disease and ulcerative colitis.

You may also be interested in the free precongress workshop – The Lloyd Mayer, MD, Young IBD Investigators Clinical, Basic, and Translational Research Workshop. This half-day precongress workshop is targeted to early-career clinical, basic, and translational researchers as well as senior researchers and will feature a mix of research presentations by young investigator colleagues, keynote presentations, and panel discussion, featuring established IBD researchers. The theme this year is focused around grant proposals and will include two mock grant review sessions.

Learn more about the Crohn’s & Colitis Congress and register: http://crohnscolitiscongress.org.
 

Publications
Sections

 

Advice on Achieving Work-Life Balance

Successfully maintaining a balance between your personal and professional lives is a difficult concept to grasp and practice to enforce. Is this thing called “work-life balance” within reach or just some elusive circumstance people talk about? The AGA Community Early Career Group was the hub for discussions on ways early-career gastroenterologists can modify their day-to-day approach to help prevent burnout.

We consolidated the advice and tips shared into a series of articles and resources to help students, trainees, and early career members get a little closer to balancing their work and professional lives. Here are some highlights:
 

Choose work-life “integration”

If your career and your personal life were a successful relationship, remember that it’s not always 50/50, and be sure to allow forgiveness and reparation when needed.

Maternity leave

When it comes to starting a family, think about your current training or career climate and how you can make it work. Be transparent with your supervisor so there aren’t any surprises, and plans can be made in advance to cover for your time away. Prepare to be flexible from the beginning.

Learn when to say “no”

Saying “yes” to too many things not only leads to overextending yourself beyond your capabilities, but you could also be losing time on what is important to you. Choose one night a week when you can work late – pack a snack, and give yourself a hard stop the rest of the week. Keep patient documentation as a daytime/work task.

Communication is key

When your partner or spouse is just as busy, it’s important to keep a joint calendar up to date and make plans far in advance. Also, create a routine: Try making time once a month to discuss calendars and anticipated events, face-to-face. When life throws a divot in your path, don’t lose sight of your priorities.

Make time for family and friends

Your career can take over as much of your life as you will allow. Making time for family and friends is rewarding and vacations, staycations, long weekends or even day trips can be great “resets.”
 

View the tip sheet and other work-life balance resources in the AGA Community Early Career Group library at http://community.gastro.org/WorkLife.
 

New Clinical Guidelines and Practice Updates

The latest AGA Clinical Practice Guideline, published in Gastroenterology, is on the role of therapeutic drug monitoring (TDM) in the management of IBD. It focuses on the application of TDM for biologic therapy, specifically anti-tumor necrosis factor-α (TNF) agents, and for thiopurines, and addresses questions on the risks and benefits of reactive TDM, routine proactive TDM, or no TDM in guiding treatment changes.

View the full guideline, technical review, and patient guide at www.gastro.org/guidelines.

In addition to guidelines, please check out the most recent Clinical Practice Updates (CPU) in Gastroenterology and Clinical Gastroenterology and Hepatology (CGH), which are often accompanied by a practice quiz from one of the authors, via the AGA Community. Visit http://community.gastro.org/guidelinecpu to test your knowledge. The most recent CPU, published in the September issue of CGH, focuses on GI side effects related to opioid medications.
 

Be Part of the Meeting to Transform IBD

If you treat patients with inflammatory bowel disease, conduct IBD research, or plan to pursue a career in IBD, join us for the inaugural Crohn’s & Colitis Congress™, taking place Jan. 18-20, 2018, in Las Vegas, NV. The Crohn’s & Colitis Foundation (formerly CCFA) and AGA have joined together to develop a must-attend program for the entire IBD care team. Expand your knowledge, network with your peers as well as IBD leaders across multiple disciplines, and get inspired to improve care for patients with Crohn’s disease and ulcerative colitis.

You may also be interested in the free precongress workshop – The Lloyd Mayer, MD, Young IBD Investigators Clinical, Basic, and Translational Research Workshop. This half-day precongress workshop is targeted to early-career clinical, basic, and translational researchers as well as senior researchers and will feature a mix of research presentations by young investigator colleagues, keynote presentations, and panel discussion, featuring established IBD researchers. The theme this year is focused around grant proposals and will include two mock grant review sessions.

Learn more about the Crohn’s & Colitis Congress and register: http://crohnscolitiscongress.org.
 

 

Advice on Achieving Work-Life Balance

Successfully maintaining a balance between your personal and professional lives is a difficult concept to grasp and practice to enforce. Is this thing called “work-life balance” within reach or just some elusive circumstance people talk about? The AGA Community Early Career Group was the hub for discussions on ways early-career gastroenterologists can modify their day-to-day approach to help prevent burnout.

We consolidated the advice and tips shared into a series of articles and resources to help students, trainees, and early career members get a little closer to balancing their work and professional lives. Here are some highlights:
 

Choose work-life “integration”

If your career and your personal life were a successful relationship, remember that it’s not always 50/50, and be sure to allow forgiveness and reparation when needed.

Maternity leave

When it comes to starting a family, think about your current training or career climate and how you can make it work. Be transparent with your supervisor so there aren’t any surprises, and plans can be made in advance to cover for your time away. Prepare to be flexible from the beginning.

Learn when to say “no”

Saying “yes” to too many things not only leads to overextending yourself beyond your capabilities, but you could also be losing time on what is important to you. Choose one night a week when you can work late – pack a snack, and give yourself a hard stop the rest of the week. Keep patient documentation as a daytime/work task.

Communication is key

When your partner or spouse is just as busy, it’s important to keep a joint calendar up to date and make plans far in advance. Also, create a routine: Try making time once a month to discuss calendars and anticipated events, face-to-face. When life throws a divot in your path, don’t lose sight of your priorities.

Make time for family and friends

Your career can take over as much of your life as you will allow. Making time for family and friends is rewarding and vacations, staycations, long weekends or even day trips can be great “resets.”
 

View the tip sheet and other work-life balance resources in the AGA Community Early Career Group library at http://community.gastro.org/WorkLife.
 

New Clinical Guidelines and Practice Updates

The latest AGA Clinical Practice Guideline, published in Gastroenterology, is on the role of therapeutic drug monitoring (TDM) in the management of IBD. It focuses on the application of TDM for biologic therapy, specifically anti-tumor necrosis factor-α (TNF) agents, and for thiopurines, and addresses questions on the risks and benefits of reactive TDM, routine proactive TDM, or no TDM in guiding treatment changes.

View the full guideline, technical review, and patient guide at www.gastro.org/guidelines.

In addition to guidelines, please check out the most recent Clinical Practice Updates (CPU) in Gastroenterology and Clinical Gastroenterology and Hepatology (CGH), which are often accompanied by a practice quiz from one of the authors, via the AGA Community. Visit http://community.gastro.org/guidelinecpu to test your knowledge. The most recent CPU, published in the September issue of CGH, focuses on GI side effects related to opioid medications.
 

Be Part of the Meeting to Transform IBD

If you treat patients with inflammatory bowel disease, conduct IBD research, or plan to pursue a career in IBD, join us for the inaugural Crohn’s & Colitis Congress™, taking place Jan. 18-20, 2018, in Las Vegas, NV. The Crohn’s & Colitis Foundation (formerly CCFA) and AGA have joined together to develop a must-attend program for the entire IBD care team. Expand your knowledge, network with your peers as well as IBD leaders across multiple disciplines, and get inspired to improve care for patients with Crohn’s disease and ulcerative colitis.

You may also be interested in the free precongress workshop – The Lloyd Mayer, MD, Young IBD Investigators Clinical, Basic, and Translational Research Workshop. This half-day precongress workshop is targeted to early-career clinical, basic, and translational researchers as well as senior researchers and will feature a mix of research presentations by young investigator colleagues, keynote presentations, and panel discussion, featuring established IBD researchers. The theme this year is focused around grant proposals and will include two mock grant review sessions.

Learn more about the Crohn’s & Colitis Congress and register: http://crohnscolitiscongress.org.
 

Publications
Publications
Article Type
Sections
Disallow All Ads
Content Gating
No Gating (article Unlocked/Free)
Alternative CME
Disqus Comments
Default

Cholangiopancreatoscopy

Article Type
Changed

 

Dear Colleagues,

In this issue of The New Gastroenterologist, the feature article examines recent advances in the field of cholangiopancreatoscopy. In this article, William Sonnier, Meir Mizrahi (University of South Alabama), and Douglas Pleskow (Beth Israel Deaconess) provide a fantastic overview of the technologic advances in the field of cholangiopancreatoscopy as well as the clinical indications for this procedure and the risks involved. Also in this issue, Deborah Fisher (Duke University) and Darrell Gray (Ohio State University) provide advice about how to appropriately and responsibly handle social media. This is an incredibly important topic, given the increasing pervasiveness of social media in many aspects of our personal and professional lives.

Bryson W. Katona, MD, PHD
Additionally, Madelin Siedler (AGA) and Yngve Falck-Ytter (Case-Western) demystify the process by which AGA guidelines are developed by outlining the workflow from inception to final publication. Also, Yamini Natarajan, Richa Shukla, and Jordan Shapiro (Baylor College of Medicine) provide an update about a recent meeting with their local representative, Gene Green (Texas’s 29th congressional district), who is the Ranking Member for the Committee on Energy and Commerce’s Subcommittee on Health.

Finally, in this issue is the second part in a series on legal issues for gastroenterologists. In this article, which is again authored by a very experienced group of attorneys, many important issues are covered, including what steps should be taken if you are sued, what you should and should not do after being sued, as well as tips on how to best prepare for both deposition and trial.

If there are topics that you would be interested in writing or hearing about in The New Gastroenterologist, please let us know. You can contact me ([email protected]) or the Managing Editor of The New Gastroenterologist, Ryan Farrell ([email protected]).
 

Sincerely,

Bryson W. Katona, MD, PhD

Editor in Chief

Bryson W. Katona is an instructor of medicine in the division of gastroenterology at the University of Pennsylvania.

Publications
Sections

 

Dear Colleagues,

In this issue of The New Gastroenterologist, the feature article examines recent advances in the field of cholangiopancreatoscopy. In this article, William Sonnier, Meir Mizrahi (University of South Alabama), and Douglas Pleskow (Beth Israel Deaconess) provide a fantastic overview of the technologic advances in the field of cholangiopancreatoscopy as well as the clinical indications for this procedure and the risks involved. Also in this issue, Deborah Fisher (Duke University) and Darrell Gray (Ohio State University) provide advice about how to appropriately and responsibly handle social media. This is an incredibly important topic, given the increasing pervasiveness of social media in many aspects of our personal and professional lives.

Bryson W. Katona, MD, PHD
Additionally, Madelin Siedler (AGA) and Yngve Falck-Ytter (Case-Western) demystify the process by which AGA guidelines are developed by outlining the workflow from inception to final publication. Also, Yamini Natarajan, Richa Shukla, and Jordan Shapiro (Baylor College of Medicine) provide an update about a recent meeting with their local representative, Gene Green (Texas’s 29th congressional district), who is the Ranking Member for the Committee on Energy and Commerce’s Subcommittee on Health.

Finally, in this issue is the second part in a series on legal issues for gastroenterologists. In this article, which is again authored by a very experienced group of attorneys, many important issues are covered, including what steps should be taken if you are sued, what you should and should not do after being sued, as well as tips on how to best prepare for both deposition and trial.

If there are topics that you would be interested in writing or hearing about in The New Gastroenterologist, please let us know. You can contact me ([email protected]) or the Managing Editor of The New Gastroenterologist, Ryan Farrell ([email protected]).
 

Sincerely,

Bryson W. Katona, MD, PhD

Editor in Chief

Bryson W. Katona is an instructor of medicine in the division of gastroenterology at the University of Pennsylvania.

 

Dear Colleagues,

In this issue of The New Gastroenterologist, the feature article examines recent advances in the field of cholangiopancreatoscopy. In this article, William Sonnier, Meir Mizrahi (University of South Alabama), and Douglas Pleskow (Beth Israel Deaconess) provide a fantastic overview of the technologic advances in the field of cholangiopancreatoscopy as well as the clinical indications for this procedure and the risks involved. Also in this issue, Deborah Fisher (Duke University) and Darrell Gray (Ohio State University) provide advice about how to appropriately and responsibly handle social media. This is an incredibly important topic, given the increasing pervasiveness of social media in many aspects of our personal and professional lives.

Bryson W. Katona, MD, PHD
Additionally, Madelin Siedler (AGA) and Yngve Falck-Ytter (Case-Western) demystify the process by which AGA guidelines are developed by outlining the workflow from inception to final publication. Also, Yamini Natarajan, Richa Shukla, and Jordan Shapiro (Baylor College of Medicine) provide an update about a recent meeting with their local representative, Gene Green (Texas’s 29th congressional district), who is the Ranking Member for the Committee on Energy and Commerce’s Subcommittee on Health.

Finally, in this issue is the second part in a series on legal issues for gastroenterologists. In this article, which is again authored by a very experienced group of attorneys, many important issues are covered, including what steps should be taken if you are sued, what you should and should not do after being sued, as well as tips on how to best prepare for both deposition and trial.

If there are topics that you would be interested in writing or hearing about in The New Gastroenterologist, please let us know. You can contact me ([email protected]) or the Managing Editor of The New Gastroenterologist, Ryan Farrell ([email protected]).
 

Sincerely,

Bryson W. Katona, MD, PhD

Editor in Chief

Bryson W. Katona is an instructor of medicine in the division of gastroenterology at the University of Pennsylvania.

Publications
Publications
Article Type
Sections
Disallow All Ads
Content Gating
No Gating (article Unlocked/Free)
Alternative CME
Disqus Comments
Default

Trustworthy Recommendations: A Closer Look Inside the AGA’s Clinical Guideline Development Process

Article Type
Changed

 

The AGA understands how important it is for busy physicians to have access to the most trustworthy, actionable, and evidence-based guidelines in order to achieve the highest possible quality of patient care. According to a 2016 survey, AGA members ranked guidelines as the most important of all AGA-specific benefits, giving guidelines an average of 4.61 out of 5 (where 5 was defined as “extremely important”). The AGA’s guidelines landing page (www.gastro.org/guidelines) has long been the most frequently accessed page on the AGA website.

Madelin R. Siedler
It is clear to AGA leaders and staff that guidelines are of great importance to our members and this awareness is reflected in the amount of time and resources spent to develop them. In developing guidelines, our goal is twofold: to maintain a high level of rigor and trustworthiness through the utilization of an evidence-based approach while remaining transparent, open, and responsive to the needs of our members, patients, and the public at large. The purpose of this article is to give the reader an in-depth understanding of the process used by the AGA to develop clinical guidelines, from the conception of topics to their eventual publication (Figure 1).

The life cycle of an AGA guideline

In 2010, the AGA Institute officially adopted the GRADE (Grades of Recommendation Assessment, Development, and Evaluation) methodology for the development of all future guidelines. Since the publication of our first GRADE-based guideline in 2013, the AGA has developed and published 12 guidelines with an additional 11 more to be published by 2019. Based on the systematic rigor of the GRADE approach, the AGA’s guideline development process was created to result in clinical recommendations that are not only evidence based but actionable and responsive to varying patient needs and preferences at the point of care.

All told, a single AGA guideline costs around $45,000 and takes approximately 24 months to complete and publish. Currently, the AGA is working to pilot new methods of shortening the time to publication through the development of rapid reviews within a focused topic (e.g., opioid-induced constipation).1 The development of each guideline requires a team of one or more specially trained GRADE methodologists, two or more content experts, a medical librarian, a panel of three or more guideline authors, two AGA staff members, and the Clinical Guidelines Committee Chair.

Dr. Yngve T. Falck-Ytter
Determining the guideline topics. Each AGA guideline begins as a simple idea submitted through the annual call for topics, which is open to the public. At their annual meeting at Digestive Disease Week®, the 15 members of the AGA Institute Clinical Guidelines Committee (CGC) review the entire list of submissions and rank a list of eight or more topics that they believe are the most timely, relevant, and impactful to the field of gastroenterology. This may include a combination of completely new topics and updates of older, out-of-date guidelines. The AGA Institute Governing Board then determines a final list of four or more topics to immediately begin development.

Determining the focused questions. First, the entire team of physician-authors determines a list of focused questions that the guideline will address. This list of focused questions is translated into a table of Population, Intervention, Comparison, Outcomes (PICOs) that operationalize the general questions into search terms utilized by the medical librarian to run the systematic search as well as define the final scope of the guideline. The focused questions and related PICOs are sent to the Governing Board for review and approval.

Developing the technical review. Over the next several months, the methodologist and content experts meet on a weekly basis to review the search results question-by-question and develop the technical review of evidence that will form the basis of the clinical recommendations. For each PICO, the technical review assesses the entire body of evidence and rates the overall quality of evidence gathered for each outcome related to the PICOs (from “very low” to “low” to “moderate” to “high”).

Rating the quality of evidence. Ratings of the quality of evidence for each PICO are based not only on the methodology used in the scientific studies (e.g., whether each study is an observational study or a randomized controlled trial) but additional categories such as publication bias (i.e., whether there is reason to believe there is a disproportionate representation of positive results in the literature) or indirectness (i.e., how directly applicable the study population and interventions are to real-life clinical scenarios). In this way, outcomes informed by randomized controlled trials might be “rated down” to a moderate quality of evidence because of indirectness, whereas a body of evidence from observational studies may be “rated up” because of large effect.

Drafting the clinical recommendations. The technical review presents the findings of the literature along with the authors’ assessment of the evidence quality. At a face-to-face meeting, these results are presented by the technical review authors to the guideline panel, who are responsible for developing the official guideline document. The role of the guideline panel is to understand the quality of evidence and determine an ultimate list of clinical recommendations and assign a strength (strong or conditional) to each recommendation, all while considering important factors such as the balance between benefits and downsides, potential variability in patients’ values and preferences, and impact on resource utilization. Oftentimes, but not always, recommendations based on higher-quality evidence for which most patients would request the recommended course of action translate into strong recommendations. Recommendations based on lower-quality evidence and those for which there is a higher variability in patient values or issues surrounding resource utilization are more likely to be conditional.

In addition to the guideline document, the guideline panel also drafts a Clinical Decision Support Tool, which illustrates the clinical recommendations within a visual algorithm. At the same time, AGA staff draft a patient summary that explains the recommendations in plain language. This summary can be used by physicians to improve clinical communication and shared decision making with their patients.2

Revising the guideline. Each AGA technical review goes through two layers of review: once by an anonymous peer-review panel of three content experts, and again during a 30-day public comment period in which both the technical review and guideline are posted for public input. The authors take all input into consideration while finalizing the documents, which are sent to the Governing Board for final approval. Once approved by the Board, the technical review, guideline, and all related materials are submitted for publication in Gastroenterology. In addition to print publication, each guideline is disseminated on the AGA website and through the official Clinical Guidelines mobile app (available via the App Store and Google Play), which includes interactive versions of the Clinical Decision Support Tools and plain-language summaries that can be sent via e-mail to patients at the point of care. The AGA is currently pursuing future directions for the dissemination and implementation of our guidelines, such as the seamless integration of clinical recommendations into electronic health records to further improve decision making and facilitate quality measurement and improvement.
 

 

Conclusion

Not all clinical guidelines are created with equal rigor. Clinicians should examine guidelines closely and consider whether or not they follow the Institute of Medicine’s standards for trustworthy clinical guidelines: Is the focus on transparency? Is a rigorous conflict of interest system in place that eliminates major sources of financial and intellectual conflict? Was an unconflicted GRADE-trained methodologist involved in ensuring that a systematic review process is followed and the method of rating the quality of evidence and strength of recommendation follows published principles? Are the recommendations clear and actionable?3 AGA Institute guidelines are developed with the goal of striking a balance between presenting the highest ideals of evidence-based medicine while remaining responsive to the needs of everyday practitioners dealing with real patients in real clinical settings.

Ms. Siedler is the director of clinical practice at the AGA Institute national office in Bethesda, Md.; Dr. Falck-Ytter is a professor of medicine at Case-Western Reserve University, Cleveland, chair of the AGA Institute Clinical Guidelines Committee, and chief of the division of gastroenterology at the Louis Stokes VA Medical Center in Cleveland. The authors disclose no conflicts of interest.

References

1. Hanson B., Siedler M., Falck-Ytter Y., Sultan S. Introducing the rapid review: How the AGA is working to get trustworthy clinical guidelines to practitioners in less time. AGA Perspectives. 2017; in press.

2. Siedler M., Allen J., Falck-Ytter Y., Weinberg D. AGA clinical practice guidelines: Robust, evidence-based tools for guiding clinical care decisions. Gastroenterology. 2015;149:493-5.

3. Institute of Medicine: Standards for developing trustworthy clinical practice guidelines. Available at http://www.nationalacademies.org/hmd/Reports/2011/Clinical-Practice-Guidelines-We-Can-Trust/Standards.aspx. Last accessed May 2017.Process for the selection of new guideline topics

Publications
Sections

 

The AGA understands how important it is for busy physicians to have access to the most trustworthy, actionable, and evidence-based guidelines in order to achieve the highest possible quality of patient care. According to a 2016 survey, AGA members ranked guidelines as the most important of all AGA-specific benefits, giving guidelines an average of 4.61 out of 5 (where 5 was defined as “extremely important”). The AGA’s guidelines landing page (www.gastro.org/guidelines) has long been the most frequently accessed page on the AGA website.

Madelin R. Siedler
It is clear to AGA leaders and staff that guidelines are of great importance to our members and this awareness is reflected in the amount of time and resources spent to develop them. In developing guidelines, our goal is twofold: to maintain a high level of rigor and trustworthiness through the utilization of an evidence-based approach while remaining transparent, open, and responsive to the needs of our members, patients, and the public at large. The purpose of this article is to give the reader an in-depth understanding of the process used by the AGA to develop clinical guidelines, from the conception of topics to their eventual publication (Figure 1).

The life cycle of an AGA guideline

In 2010, the AGA Institute officially adopted the GRADE (Grades of Recommendation Assessment, Development, and Evaluation) methodology for the development of all future guidelines. Since the publication of our first GRADE-based guideline in 2013, the AGA has developed and published 12 guidelines with an additional 11 more to be published by 2019. Based on the systematic rigor of the GRADE approach, the AGA’s guideline development process was created to result in clinical recommendations that are not only evidence based but actionable and responsive to varying patient needs and preferences at the point of care.

All told, a single AGA guideline costs around $45,000 and takes approximately 24 months to complete and publish. Currently, the AGA is working to pilot new methods of shortening the time to publication through the development of rapid reviews within a focused topic (e.g., opioid-induced constipation).1 The development of each guideline requires a team of one or more specially trained GRADE methodologists, two or more content experts, a medical librarian, a panel of three or more guideline authors, two AGA staff members, and the Clinical Guidelines Committee Chair.

Dr. Yngve T. Falck-Ytter
Determining the guideline topics. Each AGA guideline begins as a simple idea submitted through the annual call for topics, which is open to the public. At their annual meeting at Digestive Disease Week®, the 15 members of the AGA Institute Clinical Guidelines Committee (CGC) review the entire list of submissions and rank a list of eight or more topics that they believe are the most timely, relevant, and impactful to the field of gastroenterology. This may include a combination of completely new topics and updates of older, out-of-date guidelines. The AGA Institute Governing Board then determines a final list of four or more topics to immediately begin development.

Determining the focused questions. First, the entire team of physician-authors determines a list of focused questions that the guideline will address. This list of focused questions is translated into a table of Population, Intervention, Comparison, Outcomes (PICOs) that operationalize the general questions into search terms utilized by the medical librarian to run the systematic search as well as define the final scope of the guideline. The focused questions and related PICOs are sent to the Governing Board for review and approval.

Developing the technical review. Over the next several months, the methodologist and content experts meet on a weekly basis to review the search results question-by-question and develop the technical review of evidence that will form the basis of the clinical recommendations. For each PICO, the technical review assesses the entire body of evidence and rates the overall quality of evidence gathered for each outcome related to the PICOs (from “very low” to “low” to “moderate” to “high”).

Rating the quality of evidence. Ratings of the quality of evidence for each PICO are based not only on the methodology used in the scientific studies (e.g., whether each study is an observational study or a randomized controlled trial) but additional categories such as publication bias (i.e., whether there is reason to believe there is a disproportionate representation of positive results in the literature) or indirectness (i.e., how directly applicable the study population and interventions are to real-life clinical scenarios). In this way, outcomes informed by randomized controlled trials might be “rated down” to a moderate quality of evidence because of indirectness, whereas a body of evidence from observational studies may be “rated up” because of large effect.

Drafting the clinical recommendations. The technical review presents the findings of the literature along with the authors’ assessment of the evidence quality. At a face-to-face meeting, these results are presented by the technical review authors to the guideline panel, who are responsible for developing the official guideline document. The role of the guideline panel is to understand the quality of evidence and determine an ultimate list of clinical recommendations and assign a strength (strong or conditional) to each recommendation, all while considering important factors such as the balance between benefits and downsides, potential variability in patients’ values and preferences, and impact on resource utilization. Oftentimes, but not always, recommendations based on higher-quality evidence for which most patients would request the recommended course of action translate into strong recommendations. Recommendations based on lower-quality evidence and those for which there is a higher variability in patient values or issues surrounding resource utilization are more likely to be conditional.

In addition to the guideline document, the guideline panel also drafts a Clinical Decision Support Tool, which illustrates the clinical recommendations within a visual algorithm. At the same time, AGA staff draft a patient summary that explains the recommendations in plain language. This summary can be used by physicians to improve clinical communication and shared decision making with their patients.2

Revising the guideline. Each AGA technical review goes through two layers of review: once by an anonymous peer-review panel of three content experts, and again during a 30-day public comment period in which both the technical review and guideline are posted for public input. The authors take all input into consideration while finalizing the documents, which are sent to the Governing Board for final approval. Once approved by the Board, the technical review, guideline, and all related materials are submitted for publication in Gastroenterology. In addition to print publication, each guideline is disseminated on the AGA website and through the official Clinical Guidelines mobile app (available via the App Store and Google Play), which includes interactive versions of the Clinical Decision Support Tools and plain-language summaries that can be sent via e-mail to patients at the point of care. The AGA is currently pursuing future directions for the dissemination and implementation of our guidelines, such as the seamless integration of clinical recommendations into electronic health records to further improve decision making and facilitate quality measurement and improvement.
 

 

Conclusion

Not all clinical guidelines are created with equal rigor. Clinicians should examine guidelines closely and consider whether or not they follow the Institute of Medicine’s standards for trustworthy clinical guidelines: Is the focus on transparency? Is a rigorous conflict of interest system in place that eliminates major sources of financial and intellectual conflict? Was an unconflicted GRADE-trained methodologist involved in ensuring that a systematic review process is followed and the method of rating the quality of evidence and strength of recommendation follows published principles? Are the recommendations clear and actionable?3 AGA Institute guidelines are developed with the goal of striking a balance between presenting the highest ideals of evidence-based medicine while remaining responsive to the needs of everyday practitioners dealing with real patients in real clinical settings.

Ms. Siedler is the director of clinical practice at the AGA Institute national office in Bethesda, Md.; Dr. Falck-Ytter is a professor of medicine at Case-Western Reserve University, Cleveland, chair of the AGA Institute Clinical Guidelines Committee, and chief of the division of gastroenterology at the Louis Stokes VA Medical Center in Cleveland. The authors disclose no conflicts of interest.

References

1. Hanson B., Siedler M., Falck-Ytter Y., Sultan S. Introducing the rapid review: How the AGA is working to get trustworthy clinical guidelines to practitioners in less time. AGA Perspectives. 2017; in press.

2. Siedler M., Allen J., Falck-Ytter Y., Weinberg D. AGA clinical practice guidelines: Robust, evidence-based tools for guiding clinical care decisions. Gastroenterology. 2015;149:493-5.

3. Institute of Medicine: Standards for developing trustworthy clinical practice guidelines. Available at http://www.nationalacademies.org/hmd/Reports/2011/Clinical-Practice-Guidelines-We-Can-Trust/Standards.aspx. Last accessed May 2017.Process for the selection of new guideline topics

 

The AGA understands how important it is for busy physicians to have access to the most trustworthy, actionable, and evidence-based guidelines in order to achieve the highest possible quality of patient care. According to a 2016 survey, AGA members ranked guidelines as the most important of all AGA-specific benefits, giving guidelines an average of 4.61 out of 5 (where 5 was defined as “extremely important”). The AGA’s guidelines landing page (www.gastro.org/guidelines) has long been the most frequently accessed page on the AGA website.

Madelin R. Siedler
It is clear to AGA leaders and staff that guidelines are of great importance to our members and this awareness is reflected in the amount of time and resources spent to develop them. In developing guidelines, our goal is twofold: to maintain a high level of rigor and trustworthiness through the utilization of an evidence-based approach while remaining transparent, open, and responsive to the needs of our members, patients, and the public at large. The purpose of this article is to give the reader an in-depth understanding of the process used by the AGA to develop clinical guidelines, from the conception of topics to their eventual publication (Figure 1).

The life cycle of an AGA guideline

In 2010, the AGA Institute officially adopted the GRADE (Grades of Recommendation Assessment, Development, and Evaluation) methodology for the development of all future guidelines. Since the publication of our first GRADE-based guideline in 2013, the AGA has developed and published 12 guidelines with an additional 11 more to be published by 2019. Based on the systematic rigor of the GRADE approach, the AGA’s guideline development process was created to result in clinical recommendations that are not only evidence based but actionable and responsive to varying patient needs and preferences at the point of care.

All told, a single AGA guideline costs around $45,000 and takes approximately 24 months to complete and publish. Currently, the AGA is working to pilot new methods of shortening the time to publication through the development of rapid reviews within a focused topic (e.g., opioid-induced constipation).1 The development of each guideline requires a team of one or more specially trained GRADE methodologists, two or more content experts, a medical librarian, a panel of three or more guideline authors, two AGA staff members, and the Clinical Guidelines Committee Chair.

Dr. Yngve T. Falck-Ytter
Determining the guideline topics. Each AGA guideline begins as a simple idea submitted through the annual call for topics, which is open to the public. At their annual meeting at Digestive Disease Week®, the 15 members of the AGA Institute Clinical Guidelines Committee (CGC) review the entire list of submissions and rank a list of eight or more topics that they believe are the most timely, relevant, and impactful to the field of gastroenterology. This may include a combination of completely new topics and updates of older, out-of-date guidelines. The AGA Institute Governing Board then determines a final list of four or more topics to immediately begin development.

Determining the focused questions. First, the entire team of physician-authors determines a list of focused questions that the guideline will address. This list of focused questions is translated into a table of Population, Intervention, Comparison, Outcomes (PICOs) that operationalize the general questions into search terms utilized by the medical librarian to run the systematic search as well as define the final scope of the guideline. The focused questions and related PICOs are sent to the Governing Board for review and approval.

Developing the technical review. Over the next several months, the methodologist and content experts meet on a weekly basis to review the search results question-by-question and develop the technical review of evidence that will form the basis of the clinical recommendations. For each PICO, the technical review assesses the entire body of evidence and rates the overall quality of evidence gathered for each outcome related to the PICOs (from “very low” to “low” to “moderate” to “high”).

Rating the quality of evidence. Ratings of the quality of evidence for each PICO are based not only on the methodology used in the scientific studies (e.g., whether each study is an observational study or a randomized controlled trial) but additional categories such as publication bias (i.e., whether there is reason to believe there is a disproportionate representation of positive results in the literature) or indirectness (i.e., how directly applicable the study population and interventions are to real-life clinical scenarios). In this way, outcomes informed by randomized controlled trials might be “rated down” to a moderate quality of evidence because of indirectness, whereas a body of evidence from observational studies may be “rated up” because of large effect.

Drafting the clinical recommendations. The technical review presents the findings of the literature along with the authors’ assessment of the evidence quality. At a face-to-face meeting, these results are presented by the technical review authors to the guideline panel, who are responsible for developing the official guideline document. The role of the guideline panel is to understand the quality of evidence and determine an ultimate list of clinical recommendations and assign a strength (strong or conditional) to each recommendation, all while considering important factors such as the balance between benefits and downsides, potential variability in patients’ values and preferences, and impact on resource utilization. Oftentimes, but not always, recommendations based on higher-quality evidence for which most patients would request the recommended course of action translate into strong recommendations. Recommendations based on lower-quality evidence and those for which there is a higher variability in patient values or issues surrounding resource utilization are more likely to be conditional.

In addition to the guideline document, the guideline panel also drafts a Clinical Decision Support Tool, which illustrates the clinical recommendations within a visual algorithm. At the same time, AGA staff draft a patient summary that explains the recommendations in plain language. This summary can be used by physicians to improve clinical communication and shared decision making with their patients.2

Revising the guideline. Each AGA technical review goes through two layers of review: once by an anonymous peer-review panel of three content experts, and again during a 30-day public comment period in which both the technical review and guideline are posted for public input. The authors take all input into consideration while finalizing the documents, which are sent to the Governing Board for final approval. Once approved by the Board, the technical review, guideline, and all related materials are submitted for publication in Gastroenterology. In addition to print publication, each guideline is disseminated on the AGA website and through the official Clinical Guidelines mobile app (available via the App Store and Google Play), which includes interactive versions of the Clinical Decision Support Tools and plain-language summaries that can be sent via e-mail to patients at the point of care. The AGA is currently pursuing future directions for the dissemination and implementation of our guidelines, such as the seamless integration of clinical recommendations into electronic health records to further improve decision making and facilitate quality measurement and improvement.
 

 

Conclusion

Not all clinical guidelines are created with equal rigor. Clinicians should examine guidelines closely and consider whether or not they follow the Institute of Medicine’s standards for trustworthy clinical guidelines: Is the focus on transparency? Is a rigorous conflict of interest system in place that eliminates major sources of financial and intellectual conflict? Was an unconflicted GRADE-trained methodologist involved in ensuring that a systematic review process is followed and the method of rating the quality of evidence and strength of recommendation follows published principles? Are the recommendations clear and actionable?3 AGA Institute guidelines are developed with the goal of striking a balance between presenting the highest ideals of evidence-based medicine while remaining responsive to the needs of everyday practitioners dealing with real patients in real clinical settings.

Ms. Siedler is the director of clinical practice at the AGA Institute national office in Bethesda, Md.; Dr. Falck-Ytter is a professor of medicine at Case-Western Reserve University, Cleveland, chair of the AGA Institute Clinical Guidelines Committee, and chief of the division of gastroenterology at the Louis Stokes VA Medical Center in Cleveland. The authors disclose no conflicts of interest.

References

1. Hanson B., Siedler M., Falck-Ytter Y., Sultan S. Introducing the rapid review: How the AGA is working to get trustworthy clinical guidelines to practitioners in less time. AGA Perspectives. 2017; in press.

2. Siedler M., Allen J., Falck-Ytter Y., Weinberg D. AGA clinical practice guidelines: Robust, evidence-based tools for guiding clinical care decisions. Gastroenterology. 2015;149:493-5.

3. Institute of Medicine: Standards for developing trustworthy clinical practice guidelines. Available at http://www.nationalacademies.org/hmd/Reports/2011/Clinical-Practice-Guidelines-We-Can-Trust/Standards.aspx. Last accessed May 2017.Process for the selection of new guideline topics

Publications
Publications
Article Type
Sections
Disallow All Ads
Content Gating
No Gating (article Unlocked/Free)
Alternative CME
Disqus Comments
Default

Advice on Choosing Your GI Career Path

Article Type
Changed

 

Mariam Naveed, MD, opened a discussion in the Early Career Group forum in AGA Community that invited GIs to share how or when they knew which career path was the best fit. Among those sharing their stories were Peter Liang, MD, MPH; Avinash Ketwaroo, MD; Maisa Abdalla, MD, MPH; Tara Altepeter, MD; Elliot Tapper, MD; and Brijen Shah, MD. Their expertise spans across the GI spectrum, including academia, research, drug development, and regulatory science.

For Dr. Liang, the key to succeeding on the research path is to be passionate about your topic(s), enjoy reading and writing, and be able to accept constructive criticism and rejection. Dr. Altepeter encourages all GIs early in their career to be open to exploring a variety of career options, as regulatory science was not a career path she was aware of at the beginning of training.

The conversation continued when trainee and early career members brought their career-specific questions, including the possibility of achieving tenure without publishing.

View a summary of advice shared at http://community.gastro.org/calling. The discussions around finding your GI calling are in the AGA Community Early Career Group, at http://community.gastro.org/EarlyCareerGroup.
 


 

Publications
Sections

 

Mariam Naveed, MD, opened a discussion in the Early Career Group forum in AGA Community that invited GIs to share how or when they knew which career path was the best fit. Among those sharing their stories were Peter Liang, MD, MPH; Avinash Ketwaroo, MD; Maisa Abdalla, MD, MPH; Tara Altepeter, MD; Elliot Tapper, MD; and Brijen Shah, MD. Their expertise spans across the GI spectrum, including academia, research, drug development, and regulatory science.

For Dr. Liang, the key to succeeding on the research path is to be passionate about your topic(s), enjoy reading and writing, and be able to accept constructive criticism and rejection. Dr. Altepeter encourages all GIs early in their career to be open to exploring a variety of career options, as regulatory science was not a career path she was aware of at the beginning of training.

The conversation continued when trainee and early career members brought their career-specific questions, including the possibility of achieving tenure without publishing.

View a summary of advice shared at http://community.gastro.org/calling. The discussions around finding your GI calling are in the AGA Community Early Career Group, at http://community.gastro.org/EarlyCareerGroup.
 


 

 

Mariam Naveed, MD, opened a discussion in the Early Career Group forum in AGA Community that invited GIs to share how or when they knew which career path was the best fit. Among those sharing their stories were Peter Liang, MD, MPH; Avinash Ketwaroo, MD; Maisa Abdalla, MD, MPH; Tara Altepeter, MD; Elliot Tapper, MD; and Brijen Shah, MD. Their expertise spans across the GI spectrum, including academia, research, drug development, and regulatory science.

For Dr. Liang, the key to succeeding on the research path is to be passionate about your topic(s), enjoy reading and writing, and be able to accept constructive criticism and rejection. Dr. Altepeter encourages all GIs early in their career to be open to exploring a variety of career options, as regulatory science was not a career path she was aware of at the beginning of training.

The conversation continued when trainee and early career members brought their career-specific questions, including the possibility of achieving tenure without publishing.

View a summary of advice shared at http://community.gastro.org/calling. The discussions around finding your GI calling are in the AGA Community Early Career Group, at http://community.gastro.org/EarlyCareerGroup.
 


 

Publications
Publications
Article Type
Sections
Disallow All Ads
Content Gating
No Gating (article Unlocked/Free)
Alternative CME
Disqus Comments
Default

Be Kind to Yourself: Preventing Burnout in New GIs Through Self-Compassion

Article Type
Changed

 

Physician burnout is a growing epidemic, particularly in the early careers of gastroenterologists. Up to 50% of new physicians and trainees experience burnout with the first 3 years of independent practice.1 The negative consequences of burnout are well known – medical errors, depression, substance abuse, and even suicide.2,3 To meet criteria for burnout syndrome (Table 1), one must have two of three core symptoms, often experienced as phases: 1) physical and emotional exhaustion; 2) cynicism and detachment; and 3) feelings of ineffectiveness and lack of accomplishment.4

m-imagephotography / Thinkstock
Wondering if you are burned out? Check out a burnout quiz specific for physicians: Oldenburg Burnout Inventory (OLBI) developed by Dr. Evangelia Demerouti.

Emotional exhaustion, one of the earliest symptoms of burnout syndrome was reported to be as high as 63% among gastroenterologists in a survey study I conducted with colleagues a few years ago.5 Similar findings are noted amongst colorectal surgeons.6 We also noted in our study that burnout levels were highest in junior versus senior attendings, with junior attendings reporting more stress related to performing endoscopies and making split-second decisions. Interventional endoscopists may have been disproportionately affected by the latter, reporting that they were more likely to think about possible mistakes they made after work, have difficulty sleeping due to thinking about their day, and have difficulty separating work and personal life.5 Male and female physicians may progress through the phases of burnout differently, with men being more likely to experience cynicism and depersonalization first, followed by fatigue. Men may also not necessarily experience the third phase of feeling ineffective, which can be particularly dangerous because they will continue to push until there is a serious consequence. Women tend to go through all three phases of burnout beginning with emotional exhaustion, with a more rapid progression through the cynicism phase, and may end up spending the majority of their time feeling ineffective and limited in their accomplishments, a recipe for leaving medicine entirely.7

Prevention of burnout through self-compassion

Even though it may sometimes be easy to forget, most of us chose medicine as our profession because of our inherent compassion towards others and desire to care for those in need. But have we properly learned how to apply that same compassion to ourselves?

Self-compassion is one of the primary qualities of a happy, flourishing, resilient individual.8 Self-compassion is a psychological skill that can be applied to feelings of inadequacy, failure, or lack of control and includes: 1) self-kindness, 2) belief in a common humanity, and 3) mindfulness.8

There is a physiological basis to self-compassion – it deactivates our threat system (e.g., adrenaline) and activates our nurturing/caregiver system (e.g., oxytocin-opiate). This is in direct contrast to burnout, which is physiologically characterized by dysregulation of the sympathetic and parasympathetic systems and the hypothalamic–pituitary–adrenal axis.9 Indeed, there have been some studies demonstrating that a few minutes of self-compassionate behavior lowered cortisol10 and increased heart rate variability,11 both of which mediate the effects of stress on health.

Are you self-compassionate? Take a quiz! 

Self-kindness requires us to treat ourselves as kindly as we would a friend or patient in the same situation. We must consciously choose not to use harsh, self-critical language when we make mistakes. We are taught not to berate our trainees for mistakes in the clinical setting – we can be taught not to berate ourselves for shortcomings as well. Self-kindness also requires that we provide ourselves with sympathy when we experience disappointments through no fault of our own (e.g. despite all my best efforts, this clinical initiative failed) and give ourselves the opportunity to nurture and soothe ourselves when we experience pain.6 Belief in a common humanity fosters engagement with others, recognizing that nobody is perfect and that others suffer as well. Isolating ourselves because we feel ashamed, embarrassed, or “crazy” in our experience of a situation only increases our suffering. As we engage with others, we are able to view things from a different perspective and also recognize that others around us have problems too. Indeed, social support may be one of the best buffers against burnout, particularly cynicism.12 A recent meta-analysis concluded that a combination of institutional engagement techniques including reduced hours and support groups as well as access to individual behavioral techniques such as mindfulness could reduce or prevent burnout.13

I have previously commented on the practice of mindfulness in the AGA Community forums and, as a potentially stand-alone component of self-compassion training,14 recommend it here as well. In addition to traditional mindfulness-based stress-reduction courses and mindfulness meditation practice found in many hospitals and community centers, individual meditation focused on loving kindness or gratitude as well as mindful exercises such as writing a self-compassionate letter or statements to yourself can be used to offset burnout in daily life.15 From the perspective of reducing burnout, mindfulness allows us to look at our feelings of cynicism, exhaustion, and inadequacy without judgment, to view them as symptoms rather than ugly truths about ourselves and that rather than avoid or suppress these feelings, to be mindful and compassionate toward them.

Dr. Laurie A. Keefer
Self-compassion does not mean that we are indulging ourselves or denying our mistakes – we simply balance out the negative events by embracing what happened and allowing ourselves to still experience a range of positive emotion. Self-compassion enhances our careers by increasing our motivation,16 encouraging us to take risks without fear of failure, to persist despite obstacles; it fosters personal growth, and even reduces medical errors.17 Others notice our self-compassion as well, with those of us who practice experiencing healthier relationships with others (less resentment, jealousy, or competitiveness) and feeling more supported by our colleagues and friends, further buffering ourselves from burnout.18

Finally, in the spirit of self-compassion, we must not judge ourselves for needing the help of others to navigate adversity – whether that support comes from our personal or professional life, or is provided by a mental health professional, we deserve to be taken care of as much as our patients do.

For more information, please visit the following, helpful resources: www.CenterForMSC.org, www.Self-Compassion.org, and www.MindfulSelfCompassion.org.
 

 

Dr. Keefer is director, psychobehavioral research, Icahn School of Medicine at Mount Sinai, division of gastroenterology, New York, N.Y.

References

1. West C.P., Shanafelt T.D., Kolars J.C. JAMA. 2011;306[9]:952-60.

2. Maslach C., Leiter M.P. World Psychiatry. 2016;15[2]:103-11.

3. Ahola K., Honkonen T., Kivimaki M., et al. J Occup Environ Med. 2006;48[10]:1023-30.

4. Ahola K., Honkonen T., Isometsa E., et al. Soc Psychiatry Psychiatr Epidemiol. 2006;41[1]:11-7.

5. Farber B.A. J Clin Psychol. 2000;56[5]:589-94.

6. Keswani R.N., Taft T.H., Cote G.A., Keefer L. Am J Gastroenterol. 2011;106[10]:1734-40.

7. Sharma A., Sharp D.M., Walker L.G., Monson J.R. Psychooncology. 2008;17[6]:570-6.

8. Houkes I., Winants Y., Twellaar M., Verdonk P. BMC Public Health. 2011;11:240.

9. Neff K.D. Hum Dev. 2009;52[4]:211-4.

10. de Vente W., van Amsterdam J.G., Olff M., Kamphuis J.H., Emmelkamp P.M. Biomed Res Int. 2015;2015:431725.

11. Rockliff H., Karl A., McEwan K., Gilbert J., Matos M., Gilbert P. Effects of intranasal oxytocin on ‘compassion focused imagery’. Emotion. 2011;11[6]:1388-96.

12. Porges S.W. Biol Psychol. 2007;74[2]:301-7.

13. Breines J.G., Chen S. Pers Soc Psychol Bull. 2012;38[9]:1133-43.

14. Heffernan M., Quinn G.M.T., Sister R.M., Fitzpatrick JJ. Int J Nurs Pract. 2010;16[4]:366-73.

15. Crocker J., Canevello A. J Pers Soc Psychol. 2008;95[3]:555-75.

16. Thompson G., McBride R.B., Hosford C.C., Halaas G. Teach Learn Med. 2016;28[2]:174-82.

17. Nie Z., Jin Y., He L., et al. Int J Clin Exp Med. 2015;8[10]:19144-9.

18. West C.P., Dyrbye L.N., Erwin P.J., Shanafelt T.D. Lancet. 2016. Nov 5;388(10057)2272-81.

19. Luchterhand C., Rakel D., Haq C., et al. WMJ. 2015;114[3]:105-9.

20. Montero-Marin J., Tops M., Manzanera R, Piva Demarzo MM, Alvarez de Mon M, Garcia-Campayo J. Front Psychol. 2015;6:1895.

Publications
Sections

 

Physician burnout is a growing epidemic, particularly in the early careers of gastroenterologists. Up to 50% of new physicians and trainees experience burnout with the first 3 years of independent practice.1 The negative consequences of burnout are well known – medical errors, depression, substance abuse, and even suicide.2,3 To meet criteria for burnout syndrome (Table 1), one must have two of three core symptoms, often experienced as phases: 1) physical and emotional exhaustion; 2) cynicism and detachment; and 3) feelings of ineffectiveness and lack of accomplishment.4

m-imagephotography / Thinkstock
Wondering if you are burned out? Check out a burnout quiz specific for physicians: Oldenburg Burnout Inventory (OLBI) developed by Dr. Evangelia Demerouti.

Emotional exhaustion, one of the earliest symptoms of burnout syndrome was reported to be as high as 63% among gastroenterologists in a survey study I conducted with colleagues a few years ago.5 Similar findings are noted amongst colorectal surgeons.6 We also noted in our study that burnout levels were highest in junior versus senior attendings, with junior attendings reporting more stress related to performing endoscopies and making split-second decisions. Interventional endoscopists may have been disproportionately affected by the latter, reporting that they were more likely to think about possible mistakes they made after work, have difficulty sleeping due to thinking about their day, and have difficulty separating work and personal life.5 Male and female physicians may progress through the phases of burnout differently, with men being more likely to experience cynicism and depersonalization first, followed by fatigue. Men may also not necessarily experience the third phase of feeling ineffective, which can be particularly dangerous because they will continue to push until there is a serious consequence. Women tend to go through all three phases of burnout beginning with emotional exhaustion, with a more rapid progression through the cynicism phase, and may end up spending the majority of their time feeling ineffective and limited in their accomplishments, a recipe for leaving medicine entirely.7

Prevention of burnout through self-compassion

Even though it may sometimes be easy to forget, most of us chose medicine as our profession because of our inherent compassion towards others and desire to care for those in need. But have we properly learned how to apply that same compassion to ourselves?

Self-compassion is one of the primary qualities of a happy, flourishing, resilient individual.8 Self-compassion is a psychological skill that can be applied to feelings of inadequacy, failure, or lack of control and includes: 1) self-kindness, 2) belief in a common humanity, and 3) mindfulness.8

There is a physiological basis to self-compassion – it deactivates our threat system (e.g., adrenaline) and activates our nurturing/caregiver system (e.g., oxytocin-opiate). This is in direct contrast to burnout, which is physiologically characterized by dysregulation of the sympathetic and parasympathetic systems and the hypothalamic–pituitary–adrenal axis.9 Indeed, there have been some studies demonstrating that a few minutes of self-compassionate behavior lowered cortisol10 and increased heart rate variability,11 both of which mediate the effects of stress on health.

Are you self-compassionate? Take a quiz! 

Self-kindness requires us to treat ourselves as kindly as we would a friend or patient in the same situation. We must consciously choose not to use harsh, self-critical language when we make mistakes. We are taught not to berate our trainees for mistakes in the clinical setting – we can be taught not to berate ourselves for shortcomings as well. Self-kindness also requires that we provide ourselves with sympathy when we experience disappointments through no fault of our own (e.g. despite all my best efforts, this clinical initiative failed) and give ourselves the opportunity to nurture and soothe ourselves when we experience pain.6 Belief in a common humanity fosters engagement with others, recognizing that nobody is perfect and that others suffer as well. Isolating ourselves because we feel ashamed, embarrassed, or “crazy” in our experience of a situation only increases our suffering. As we engage with others, we are able to view things from a different perspective and also recognize that others around us have problems too. Indeed, social support may be one of the best buffers against burnout, particularly cynicism.12 A recent meta-analysis concluded that a combination of institutional engagement techniques including reduced hours and support groups as well as access to individual behavioral techniques such as mindfulness could reduce or prevent burnout.13

I have previously commented on the practice of mindfulness in the AGA Community forums and, as a potentially stand-alone component of self-compassion training,14 recommend it here as well. In addition to traditional mindfulness-based stress-reduction courses and mindfulness meditation practice found in many hospitals and community centers, individual meditation focused on loving kindness or gratitude as well as mindful exercises such as writing a self-compassionate letter or statements to yourself can be used to offset burnout in daily life.15 From the perspective of reducing burnout, mindfulness allows us to look at our feelings of cynicism, exhaustion, and inadequacy without judgment, to view them as symptoms rather than ugly truths about ourselves and that rather than avoid or suppress these feelings, to be mindful and compassionate toward them.

Dr. Laurie A. Keefer
Self-compassion does not mean that we are indulging ourselves or denying our mistakes – we simply balance out the negative events by embracing what happened and allowing ourselves to still experience a range of positive emotion. Self-compassion enhances our careers by increasing our motivation,16 encouraging us to take risks without fear of failure, to persist despite obstacles; it fosters personal growth, and even reduces medical errors.17 Others notice our self-compassion as well, with those of us who practice experiencing healthier relationships with others (less resentment, jealousy, or competitiveness) and feeling more supported by our colleagues and friends, further buffering ourselves from burnout.18

Finally, in the spirit of self-compassion, we must not judge ourselves for needing the help of others to navigate adversity – whether that support comes from our personal or professional life, or is provided by a mental health professional, we deserve to be taken care of as much as our patients do.

For more information, please visit the following, helpful resources: www.CenterForMSC.org, www.Self-Compassion.org, and www.MindfulSelfCompassion.org.
 

 

Dr. Keefer is director, psychobehavioral research, Icahn School of Medicine at Mount Sinai, division of gastroenterology, New York, N.Y.

References

1. West C.P., Shanafelt T.D., Kolars J.C. JAMA. 2011;306[9]:952-60.

2. Maslach C., Leiter M.P. World Psychiatry. 2016;15[2]:103-11.

3. Ahola K., Honkonen T., Kivimaki M., et al. J Occup Environ Med. 2006;48[10]:1023-30.

4. Ahola K., Honkonen T., Isometsa E., et al. Soc Psychiatry Psychiatr Epidemiol. 2006;41[1]:11-7.

5. Farber B.A. J Clin Psychol. 2000;56[5]:589-94.

6. Keswani R.N., Taft T.H., Cote G.A., Keefer L. Am J Gastroenterol. 2011;106[10]:1734-40.

7. Sharma A., Sharp D.M., Walker L.G., Monson J.R. Psychooncology. 2008;17[6]:570-6.

8. Houkes I., Winants Y., Twellaar M., Verdonk P. BMC Public Health. 2011;11:240.

9. Neff K.D. Hum Dev. 2009;52[4]:211-4.

10. de Vente W., van Amsterdam J.G., Olff M., Kamphuis J.H., Emmelkamp P.M. Biomed Res Int. 2015;2015:431725.

11. Rockliff H., Karl A., McEwan K., Gilbert J., Matos M., Gilbert P. Effects of intranasal oxytocin on ‘compassion focused imagery’. Emotion. 2011;11[6]:1388-96.

12. Porges S.W. Biol Psychol. 2007;74[2]:301-7.

13. Breines J.G., Chen S. Pers Soc Psychol Bull. 2012;38[9]:1133-43.

14. Heffernan M., Quinn G.M.T., Sister R.M., Fitzpatrick JJ. Int J Nurs Pract. 2010;16[4]:366-73.

15. Crocker J., Canevello A. J Pers Soc Psychol. 2008;95[3]:555-75.

16. Thompson G., McBride R.B., Hosford C.C., Halaas G. Teach Learn Med. 2016;28[2]:174-82.

17. Nie Z., Jin Y., He L., et al. Int J Clin Exp Med. 2015;8[10]:19144-9.

18. West C.P., Dyrbye L.N., Erwin P.J., Shanafelt T.D. Lancet. 2016. Nov 5;388(10057)2272-81.

19. Luchterhand C., Rakel D., Haq C., et al. WMJ. 2015;114[3]:105-9.

20. Montero-Marin J., Tops M., Manzanera R, Piva Demarzo MM, Alvarez de Mon M, Garcia-Campayo J. Front Psychol. 2015;6:1895.

 

Physician burnout is a growing epidemic, particularly in the early careers of gastroenterologists. Up to 50% of new physicians and trainees experience burnout with the first 3 years of independent practice.1 The negative consequences of burnout are well known – medical errors, depression, substance abuse, and even suicide.2,3 To meet criteria for burnout syndrome (Table 1), one must have two of three core symptoms, often experienced as phases: 1) physical and emotional exhaustion; 2) cynicism and detachment; and 3) feelings of ineffectiveness and lack of accomplishment.4

m-imagephotography / Thinkstock
Wondering if you are burned out? Check out a burnout quiz specific for physicians: Oldenburg Burnout Inventory (OLBI) developed by Dr. Evangelia Demerouti.

Emotional exhaustion, one of the earliest symptoms of burnout syndrome was reported to be as high as 63% among gastroenterologists in a survey study I conducted with colleagues a few years ago.5 Similar findings are noted amongst colorectal surgeons.6 We also noted in our study that burnout levels were highest in junior versus senior attendings, with junior attendings reporting more stress related to performing endoscopies and making split-second decisions. Interventional endoscopists may have been disproportionately affected by the latter, reporting that they were more likely to think about possible mistakes they made after work, have difficulty sleeping due to thinking about their day, and have difficulty separating work and personal life.5 Male and female physicians may progress through the phases of burnout differently, with men being more likely to experience cynicism and depersonalization first, followed by fatigue. Men may also not necessarily experience the third phase of feeling ineffective, which can be particularly dangerous because they will continue to push until there is a serious consequence. Women tend to go through all three phases of burnout beginning with emotional exhaustion, with a more rapid progression through the cynicism phase, and may end up spending the majority of their time feeling ineffective and limited in their accomplishments, a recipe for leaving medicine entirely.7

Prevention of burnout through self-compassion

Even though it may sometimes be easy to forget, most of us chose medicine as our profession because of our inherent compassion towards others and desire to care for those in need. But have we properly learned how to apply that same compassion to ourselves?

Self-compassion is one of the primary qualities of a happy, flourishing, resilient individual.8 Self-compassion is a psychological skill that can be applied to feelings of inadequacy, failure, or lack of control and includes: 1) self-kindness, 2) belief in a common humanity, and 3) mindfulness.8

There is a physiological basis to self-compassion – it deactivates our threat system (e.g., adrenaline) and activates our nurturing/caregiver system (e.g., oxytocin-opiate). This is in direct contrast to burnout, which is physiologically characterized by dysregulation of the sympathetic and parasympathetic systems and the hypothalamic–pituitary–adrenal axis.9 Indeed, there have been some studies demonstrating that a few minutes of self-compassionate behavior lowered cortisol10 and increased heart rate variability,11 both of which mediate the effects of stress on health.

Are you self-compassionate? Take a quiz! 

Self-kindness requires us to treat ourselves as kindly as we would a friend or patient in the same situation. We must consciously choose not to use harsh, self-critical language when we make mistakes. We are taught not to berate our trainees for mistakes in the clinical setting – we can be taught not to berate ourselves for shortcomings as well. Self-kindness also requires that we provide ourselves with sympathy when we experience disappointments through no fault of our own (e.g. despite all my best efforts, this clinical initiative failed) and give ourselves the opportunity to nurture and soothe ourselves when we experience pain.6 Belief in a common humanity fosters engagement with others, recognizing that nobody is perfect and that others suffer as well. Isolating ourselves because we feel ashamed, embarrassed, or “crazy” in our experience of a situation only increases our suffering. As we engage with others, we are able to view things from a different perspective and also recognize that others around us have problems too. Indeed, social support may be one of the best buffers against burnout, particularly cynicism.12 A recent meta-analysis concluded that a combination of institutional engagement techniques including reduced hours and support groups as well as access to individual behavioral techniques such as mindfulness could reduce or prevent burnout.13

I have previously commented on the practice of mindfulness in the AGA Community forums and, as a potentially stand-alone component of self-compassion training,14 recommend it here as well. In addition to traditional mindfulness-based stress-reduction courses and mindfulness meditation practice found in many hospitals and community centers, individual meditation focused on loving kindness or gratitude as well as mindful exercises such as writing a self-compassionate letter or statements to yourself can be used to offset burnout in daily life.15 From the perspective of reducing burnout, mindfulness allows us to look at our feelings of cynicism, exhaustion, and inadequacy without judgment, to view them as symptoms rather than ugly truths about ourselves and that rather than avoid or suppress these feelings, to be mindful and compassionate toward them.

Dr. Laurie A. Keefer
Self-compassion does not mean that we are indulging ourselves or denying our mistakes – we simply balance out the negative events by embracing what happened and allowing ourselves to still experience a range of positive emotion. Self-compassion enhances our careers by increasing our motivation,16 encouraging us to take risks without fear of failure, to persist despite obstacles; it fosters personal growth, and even reduces medical errors.17 Others notice our self-compassion as well, with those of us who practice experiencing healthier relationships with others (less resentment, jealousy, or competitiveness) and feeling more supported by our colleagues and friends, further buffering ourselves from burnout.18

Finally, in the spirit of self-compassion, we must not judge ourselves for needing the help of others to navigate adversity – whether that support comes from our personal or professional life, or is provided by a mental health professional, we deserve to be taken care of as much as our patients do.

For more information, please visit the following, helpful resources: www.CenterForMSC.org, www.Self-Compassion.org, and www.MindfulSelfCompassion.org.
 

 

Dr. Keefer is director, psychobehavioral research, Icahn School of Medicine at Mount Sinai, division of gastroenterology, New York, N.Y.

References

1. West C.P., Shanafelt T.D., Kolars J.C. JAMA. 2011;306[9]:952-60.

2. Maslach C., Leiter M.P. World Psychiatry. 2016;15[2]:103-11.

3. Ahola K., Honkonen T., Kivimaki M., et al. J Occup Environ Med. 2006;48[10]:1023-30.

4. Ahola K., Honkonen T., Isometsa E., et al. Soc Psychiatry Psychiatr Epidemiol. 2006;41[1]:11-7.

5. Farber B.A. J Clin Psychol. 2000;56[5]:589-94.

6. Keswani R.N., Taft T.H., Cote G.A., Keefer L. Am J Gastroenterol. 2011;106[10]:1734-40.

7. Sharma A., Sharp D.M., Walker L.G., Monson J.R. Psychooncology. 2008;17[6]:570-6.

8. Houkes I., Winants Y., Twellaar M., Verdonk P. BMC Public Health. 2011;11:240.

9. Neff K.D. Hum Dev. 2009;52[4]:211-4.

10. de Vente W., van Amsterdam J.G., Olff M., Kamphuis J.H., Emmelkamp P.M. Biomed Res Int. 2015;2015:431725.

11. Rockliff H., Karl A., McEwan K., Gilbert J., Matos M., Gilbert P. Effects of intranasal oxytocin on ‘compassion focused imagery’. Emotion. 2011;11[6]:1388-96.

12. Porges S.W. Biol Psychol. 2007;74[2]:301-7.

13. Breines J.G., Chen S. Pers Soc Psychol Bull. 2012;38[9]:1133-43.

14. Heffernan M., Quinn G.M.T., Sister R.M., Fitzpatrick JJ. Int J Nurs Pract. 2010;16[4]:366-73.

15. Crocker J., Canevello A. J Pers Soc Psychol. 2008;95[3]:555-75.

16. Thompson G., McBride R.B., Hosford C.C., Halaas G. Teach Learn Med. 2016;28[2]:174-82.

17. Nie Z., Jin Y., He L., et al. Int J Clin Exp Med. 2015;8[10]:19144-9.

18. West C.P., Dyrbye L.N., Erwin P.J., Shanafelt T.D. Lancet. 2016. Nov 5;388(10057)2272-81.

19. Luchterhand C., Rakel D., Haq C., et al. WMJ. 2015;114[3]:105-9.

20. Montero-Marin J., Tops M., Manzanera R, Piva Demarzo MM, Alvarez de Mon M, Garcia-Campayo J. Front Psychol. 2015;6:1895.

Publications
Publications
Article Type
Sections
Disallow All Ads
Content Gating
No Gating (article Unlocked/Free)
Alternative CME
Disqus Comments
Default

Diversity in GI Training: A Timely Goal

Article Type
Changed

There is no denying that practicing medicine calls us to serve a population that is diverse in many aspects. We live and work in a world that is evolving so quickly that medical workforce demographics fail to keep pace. In the U.S. in particular, racial and ethnic diversity has already exceeded many previous forecasts and will likely continue to do so.

Dr. Sandra M. Quezada
According to current U.S. Census Bureau estimates, by 2020, 50.2% of newborn children will be of non-white race, and by the year 2044, the non-white population will comprise 50.3% of all Americans, meaning “minority” and “majority” terminology will no longer apply1 (Figure 1). Despite this rapid growth of the minority sector, corresponding trends in the practicing physician population have not yet emerged. Gastroenterology is no exception. Today, women represent 47% of U.S. medical students, however only 16% of GI fellows are women2 (Figure 2). In 2007, only 3.2% of GI fellows were African American, and 8.5% were Hispanic, despite representing approximately 13.3% and 17.6% of the U.S. population, respectively3. Of course, medical specialty selection is a two-way street on which the hopes and visions of applicants converge with those of fellowship training programs. Could we do a better job of inspiring women and minority applicants to pursue gastroenterology?

Underrepresented minority (URM) medical school graduates tend to select primary care career pathways over specialty training4, and women graduates are more likely to select fields with high proportions of female physicians such as pediatrics, obstetrics, and gynecology2. As a result, GI fellowship programs may have a small pool of women and minority candidates from which to choose. In addition, recruitment of URM medical graduates to gastroenterology is particularly challenging given the 15-year long flat rate of URM medical school matriculation3. In the case of African American men, it has not only failed to increase but actually declined in recent years, suggesting progress is not just slow but moving in the wrong direction. When considering these data, we must wonder if we’re simply observing a longer than anticipated lag and hope that, in time, there will be improved representation across medical schools, residencies, and fellowship training programs.
 

 

The American Gastroenterological Association (AGA) recognizes that broader representation in the GI workforce requires increasing diversity at the trainee level and values this change for reasons beyond diversity for diversity’s sake. Based on education research, improving diversity at the trainee level helps learners thrive through the sharing of varied perspectives and enhancement of complex, critical thinking5. Moreover, diverse learning environments promote a culture of tolerance and understanding, tools needed to prepare trainees for future patient interactions. Diversity also translates into better patient satisfaction, as several studies have shown that physician-patient concordance on race, ethnicity, and gender result in higher patient satisfaction scores6. Additionally, minority physicians are more likely to practice in underserved areas and to conduct research addressing health care disparities, an area that will require an even greater investment as the U.S. population demographic continues to evolve3,7.

AGA committed to changing the face of GI 25 years ago when it formed a dedicated diversity committee, whose current charge is to further the strategic plan by meeting the needs of underrepresented members (which includes the spectrum of diversity as defined by race, gender, culture, ethnicity, religion, or sexual preference). The committee fosters and promotes involvement, advancement, and recognition of underrepresented diverse constituents; and through policy recommendations and programs, supports AGA members’ ability to address barriers to access and utilization of healthcare services among diverse patient populations, with attention to linguistic, racial, cultural, religious, sexual preference, age, and economic diversity. As a proud current member of the AGA Institute’s Diversity Committee, I would like to share the recently developed AGA Diversity Policy, the first of its kind for the organization:


 

The AGA is committed to diversity, which is an inclusive concept that encompasses race, ethnicity, national origin, religion, gender, age, sexual orientation, and disability. We strive to cultivate diversity within the organization at all levels, including governance, committee structure, staffing, and program and policy development. We are committed to the following goals intended to reflect the interests of the diverse patient population we serve:

1) Promotion of diversity within the practice of gastroenterology and in the individual care of patients of all backgrounds.

2) Recruitment and retention of GI providers and researchers from diverse backgrounds and the support of the advancement of their careers.

3) Elimination of disparities in GI diseases through community engagement, research, and advocacy.

CRD crew
With input from the AGA Institute Diversity Committee, the AGA has spearheaded several initiatives to increase racial and ethnic diversity at the trainee level. One such initiative is the Investing in the Future Program, which engages URM college and medical students in GI health careers and research. To date, this program has reached over 2,300 students and several of these participants have chosen GI due to early exposure and mentorship. In addition, a dedicated workgroup within the AGA Institute Diversity Committee will work with trainee members to propose a long term strategy to AGA leadership to promote GI workforce diversity.
 

 

Gastroenterology has been the most competitive fellowship specialty for the past 4 consecutive years, above pediatric surgery and cardiology8. We are privileged to practice an exciting, fascinating specialty that demands diversity of skill, acuity of care, and knowledge of pathophysiology. Increased diversity among those who research, teach, and practice in this wonderful field will only enhance it, and being mindful of this goal in our recruitment and retention efforts will help us achieve it.

For more information on the AGA Institute Diversity Committee and its ongoing initiatives, please visit http://www.gastro.org/about/people/committees/diversity-committee. Additionally, any specific enquiries should be addressed to Taylor Monson ([email protected]).
 

Dr. Quezeda is assistant dean for admissions, assistant professor of medicine, division of gastroenterology and hepatology, University of Maryland School of Medicine, Baltimore, and a member of the AGA Institute Diversity Committee.

On behalf of the AGA Institute Diversity Committee: Rotonya M. Carr, MD (Chair, AGA Diversity Committee; assistant professor of medicine, division of gastroenterology, University of Pennsylvania, Philadelphia), Karen A. Chachu, MD, PhD (assistant professor of medicine, Duke University, Durham, N.C.), Elizabeth Coss, MD (clinical assistant professor, University of Texas Health Science Center at San Antonio), Maria Cruz-Correa, MD PhD (associate professor of medicine, biochemistry and surgery, University of Puerto Rico Comprehensive Cancer Center), Lukejohn Day, MD (associate clinical professor, University of California, San Francisco), Darrell M. Gray II, MD, MPH (assistant professor of medicine, The Ohio State University Wexner Medical Center), Esi Lamouse-Smith, MD, PhD (assistant professor of pediatrics, Columbia University, New York), Antonio Mendoza Ladd, MD (assistant professor, Texas Tech University Health Sciences Center, El Paso), and Celena NuQuay (AGA staff liaison).

References

1. Projections of the Size and Composition of the U.S. Population: 2014 to 2060 Population Estimates and Projections Current Population Reports. Colby S, Ortman JM. Issued March 2015.

2. Association of American Medical Colleges 2016 Physician Specialty Databook, https://www.aamc.org/data/workforce/reports/457712/2016-specialty-databook.html.

3. Association of American Medical Colleges Diversity in the Physician Workforce: Facts and Figures 2010.

4. Deville C, Hwang WT, Burgos R. Diversity in Graduate Medical Education in the United States by Race, Ethnicity, and Sex, 2012. JAMA Intern Med. 2015;175(10):1706-8.

5. Wells AS, Fox L, Cordova-Cobo D. How Racially Diverse Schools and Classrooms Can Benefit All Students. The Century Foundation, Feb 2016. https://tcf.org/content/report/how-racially-diverse-schools-and-classrooms-can-benefit-all-students/.

6. Johnson RL, Saha S, Arbelaez JJ et al. Racial and ethnic differences in patient perceptions of bias and cultural competence in health care. J Gen Intern Med. 2004 Feb;19(2):101-10.

7. Saha S, Guiton G, Wimmers PF et al. Student body racial and ethnic composition and diversity-related outcomes in US medical schools. JAMA. 2008 Sep 10;300(10):1135-45.

8. Association of American Medical Colleges, ERAS Data. https://www.aamc.org/services/eras/stats/359278/stats.html.
 

Publications
Sections

There is no denying that practicing medicine calls us to serve a population that is diverse in many aspects. We live and work in a world that is evolving so quickly that medical workforce demographics fail to keep pace. In the U.S. in particular, racial and ethnic diversity has already exceeded many previous forecasts and will likely continue to do so.

Dr. Sandra M. Quezada
According to current U.S. Census Bureau estimates, by 2020, 50.2% of newborn children will be of non-white race, and by the year 2044, the non-white population will comprise 50.3% of all Americans, meaning “minority” and “majority” terminology will no longer apply1 (Figure 1). Despite this rapid growth of the minority sector, corresponding trends in the practicing physician population have not yet emerged. Gastroenterology is no exception. Today, women represent 47% of U.S. medical students, however only 16% of GI fellows are women2 (Figure 2). In 2007, only 3.2% of GI fellows were African American, and 8.5% were Hispanic, despite representing approximately 13.3% and 17.6% of the U.S. population, respectively3. Of course, medical specialty selection is a two-way street on which the hopes and visions of applicants converge with those of fellowship training programs. Could we do a better job of inspiring women and minority applicants to pursue gastroenterology?

Underrepresented minority (URM) medical school graduates tend to select primary care career pathways over specialty training4, and women graduates are more likely to select fields with high proportions of female physicians such as pediatrics, obstetrics, and gynecology2. As a result, GI fellowship programs may have a small pool of women and minority candidates from which to choose. In addition, recruitment of URM medical graduates to gastroenterology is particularly challenging given the 15-year long flat rate of URM medical school matriculation3. In the case of African American men, it has not only failed to increase but actually declined in recent years, suggesting progress is not just slow but moving in the wrong direction. When considering these data, we must wonder if we’re simply observing a longer than anticipated lag and hope that, in time, there will be improved representation across medical schools, residencies, and fellowship training programs.
 

 

The American Gastroenterological Association (AGA) recognizes that broader representation in the GI workforce requires increasing diversity at the trainee level and values this change for reasons beyond diversity for diversity’s sake. Based on education research, improving diversity at the trainee level helps learners thrive through the sharing of varied perspectives and enhancement of complex, critical thinking5. Moreover, diverse learning environments promote a culture of tolerance and understanding, tools needed to prepare trainees for future patient interactions. Diversity also translates into better patient satisfaction, as several studies have shown that physician-patient concordance on race, ethnicity, and gender result in higher patient satisfaction scores6. Additionally, minority physicians are more likely to practice in underserved areas and to conduct research addressing health care disparities, an area that will require an even greater investment as the U.S. population demographic continues to evolve3,7.

AGA committed to changing the face of GI 25 years ago when it formed a dedicated diversity committee, whose current charge is to further the strategic plan by meeting the needs of underrepresented members (which includes the spectrum of diversity as defined by race, gender, culture, ethnicity, religion, or sexual preference). The committee fosters and promotes involvement, advancement, and recognition of underrepresented diverse constituents; and through policy recommendations and programs, supports AGA members’ ability to address barriers to access and utilization of healthcare services among diverse patient populations, with attention to linguistic, racial, cultural, religious, sexual preference, age, and economic diversity. As a proud current member of the AGA Institute’s Diversity Committee, I would like to share the recently developed AGA Diversity Policy, the first of its kind for the organization:


 

The AGA is committed to diversity, which is an inclusive concept that encompasses race, ethnicity, national origin, religion, gender, age, sexual orientation, and disability. We strive to cultivate diversity within the organization at all levels, including governance, committee structure, staffing, and program and policy development. We are committed to the following goals intended to reflect the interests of the diverse patient population we serve:

1) Promotion of diversity within the practice of gastroenterology and in the individual care of patients of all backgrounds.

2) Recruitment and retention of GI providers and researchers from diverse backgrounds and the support of the advancement of their careers.

3) Elimination of disparities in GI diseases through community engagement, research, and advocacy.

CRD crew
With input from the AGA Institute Diversity Committee, the AGA has spearheaded several initiatives to increase racial and ethnic diversity at the trainee level. One such initiative is the Investing in the Future Program, which engages URM college and medical students in GI health careers and research. To date, this program has reached over 2,300 students and several of these participants have chosen GI due to early exposure and mentorship. In addition, a dedicated workgroup within the AGA Institute Diversity Committee will work with trainee members to propose a long term strategy to AGA leadership to promote GI workforce diversity.
 

 

Gastroenterology has been the most competitive fellowship specialty for the past 4 consecutive years, above pediatric surgery and cardiology8. We are privileged to practice an exciting, fascinating specialty that demands diversity of skill, acuity of care, and knowledge of pathophysiology. Increased diversity among those who research, teach, and practice in this wonderful field will only enhance it, and being mindful of this goal in our recruitment and retention efforts will help us achieve it.

For more information on the AGA Institute Diversity Committee and its ongoing initiatives, please visit http://www.gastro.org/about/people/committees/diversity-committee. Additionally, any specific enquiries should be addressed to Taylor Monson ([email protected]).
 

Dr. Quezeda is assistant dean for admissions, assistant professor of medicine, division of gastroenterology and hepatology, University of Maryland School of Medicine, Baltimore, and a member of the AGA Institute Diversity Committee.

On behalf of the AGA Institute Diversity Committee: Rotonya M. Carr, MD (Chair, AGA Diversity Committee; assistant professor of medicine, division of gastroenterology, University of Pennsylvania, Philadelphia), Karen A. Chachu, MD, PhD (assistant professor of medicine, Duke University, Durham, N.C.), Elizabeth Coss, MD (clinical assistant professor, University of Texas Health Science Center at San Antonio), Maria Cruz-Correa, MD PhD (associate professor of medicine, biochemistry and surgery, University of Puerto Rico Comprehensive Cancer Center), Lukejohn Day, MD (associate clinical professor, University of California, San Francisco), Darrell M. Gray II, MD, MPH (assistant professor of medicine, The Ohio State University Wexner Medical Center), Esi Lamouse-Smith, MD, PhD (assistant professor of pediatrics, Columbia University, New York), Antonio Mendoza Ladd, MD (assistant professor, Texas Tech University Health Sciences Center, El Paso), and Celena NuQuay (AGA staff liaison).

References

1. Projections of the Size and Composition of the U.S. Population: 2014 to 2060 Population Estimates and Projections Current Population Reports. Colby S, Ortman JM. Issued March 2015.

2. Association of American Medical Colleges 2016 Physician Specialty Databook, https://www.aamc.org/data/workforce/reports/457712/2016-specialty-databook.html.

3. Association of American Medical Colleges Diversity in the Physician Workforce: Facts and Figures 2010.

4. Deville C, Hwang WT, Burgos R. Diversity in Graduate Medical Education in the United States by Race, Ethnicity, and Sex, 2012. JAMA Intern Med. 2015;175(10):1706-8.

5. Wells AS, Fox L, Cordova-Cobo D. How Racially Diverse Schools and Classrooms Can Benefit All Students. The Century Foundation, Feb 2016. https://tcf.org/content/report/how-racially-diverse-schools-and-classrooms-can-benefit-all-students/.

6. Johnson RL, Saha S, Arbelaez JJ et al. Racial and ethnic differences in patient perceptions of bias and cultural competence in health care. J Gen Intern Med. 2004 Feb;19(2):101-10.

7. Saha S, Guiton G, Wimmers PF et al. Student body racial and ethnic composition and diversity-related outcomes in US medical schools. JAMA. 2008 Sep 10;300(10):1135-45.

8. Association of American Medical Colleges, ERAS Data. https://www.aamc.org/services/eras/stats/359278/stats.html.
 

There is no denying that practicing medicine calls us to serve a population that is diverse in many aspects. We live and work in a world that is evolving so quickly that medical workforce demographics fail to keep pace. In the U.S. in particular, racial and ethnic diversity has already exceeded many previous forecasts and will likely continue to do so.

Dr. Sandra M. Quezada
According to current U.S. Census Bureau estimates, by 2020, 50.2% of newborn children will be of non-white race, and by the year 2044, the non-white population will comprise 50.3% of all Americans, meaning “minority” and “majority” terminology will no longer apply1 (Figure 1). Despite this rapid growth of the minority sector, corresponding trends in the practicing physician population have not yet emerged. Gastroenterology is no exception. Today, women represent 47% of U.S. medical students, however only 16% of GI fellows are women2 (Figure 2). In 2007, only 3.2% of GI fellows were African American, and 8.5% were Hispanic, despite representing approximately 13.3% and 17.6% of the U.S. population, respectively3. Of course, medical specialty selection is a two-way street on which the hopes and visions of applicants converge with those of fellowship training programs. Could we do a better job of inspiring women and minority applicants to pursue gastroenterology?

Underrepresented minority (URM) medical school graduates tend to select primary care career pathways over specialty training4, and women graduates are more likely to select fields with high proportions of female physicians such as pediatrics, obstetrics, and gynecology2. As a result, GI fellowship programs may have a small pool of women and minority candidates from which to choose. In addition, recruitment of URM medical graduates to gastroenterology is particularly challenging given the 15-year long flat rate of URM medical school matriculation3. In the case of African American men, it has not only failed to increase but actually declined in recent years, suggesting progress is not just slow but moving in the wrong direction. When considering these data, we must wonder if we’re simply observing a longer than anticipated lag and hope that, in time, there will be improved representation across medical schools, residencies, and fellowship training programs.
 

 

The American Gastroenterological Association (AGA) recognizes that broader representation in the GI workforce requires increasing diversity at the trainee level and values this change for reasons beyond diversity for diversity’s sake. Based on education research, improving diversity at the trainee level helps learners thrive through the sharing of varied perspectives and enhancement of complex, critical thinking5. Moreover, diverse learning environments promote a culture of tolerance and understanding, tools needed to prepare trainees for future patient interactions. Diversity also translates into better patient satisfaction, as several studies have shown that physician-patient concordance on race, ethnicity, and gender result in higher patient satisfaction scores6. Additionally, minority physicians are more likely to practice in underserved areas and to conduct research addressing health care disparities, an area that will require an even greater investment as the U.S. population demographic continues to evolve3,7.

AGA committed to changing the face of GI 25 years ago when it formed a dedicated diversity committee, whose current charge is to further the strategic plan by meeting the needs of underrepresented members (which includes the spectrum of diversity as defined by race, gender, culture, ethnicity, religion, or sexual preference). The committee fosters and promotes involvement, advancement, and recognition of underrepresented diverse constituents; and through policy recommendations and programs, supports AGA members’ ability to address barriers to access and utilization of healthcare services among diverse patient populations, with attention to linguistic, racial, cultural, religious, sexual preference, age, and economic diversity. As a proud current member of the AGA Institute’s Diversity Committee, I would like to share the recently developed AGA Diversity Policy, the first of its kind for the organization:


 

The AGA is committed to diversity, which is an inclusive concept that encompasses race, ethnicity, national origin, religion, gender, age, sexual orientation, and disability. We strive to cultivate diversity within the organization at all levels, including governance, committee structure, staffing, and program and policy development. We are committed to the following goals intended to reflect the interests of the diverse patient population we serve:

1) Promotion of diversity within the practice of gastroenterology and in the individual care of patients of all backgrounds.

2) Recruitment and retention of GI providers and researchers from diverse backgrounds and the support of the advancement of their careers.

3) Elimination of disparities in GI diseases through community engagement, research, and advocacy.

CRD crew
With input from the AGA Institute Diversity Committee, the AGA has spearheaded several initiatives to increase racial and ethnic diversity at the trainee level. One such initiative is the Investing in the Future Program, which engages URM college and medical students in GI health careers and research. To date, this program has reached over 2,300 students and several of these participants have chosen GI due to early exposure and mentorship. In addition, a dedicated workgroup within the AGA Institute Diversity Committee will work with trainee members to propose a long term strategy to AGA leadership to promote GI workforce diversity.
 

 

Gastroenterology has been the most competitive fellowship specialty for the past 4 consecutive years, above pediatric surgery and cardiology8. We are privileged to practice an exciting, fascinating specialty that demands diversity of skill, acuity of care, and knowledge of pathophysiology. Increased diversity among those who research, teach, and practice in this wonderful field will only enhance it, and being mindful of this goal in our recruitment and retention efforts will help us achieve it.

For more information on the AGA Institute Diversity Committee and its ongoing initiatives, please visit http://www.gastro.org/about/people/committees/diversity-committee. Additionally, any specific enquiries should be addressed to Taylor Monson ([email protected]).
 

Dr. Quezeda is assistant dean for admissions, assistant professor of medicine, division of gastroenterology and hepatology, University of Maryland School of Medicine, Baltimore, and a member of the AGA Institute Diversity Committee.

On behalf of the AGA Institute Diversity Committee: Rotonya M. Carr, MD (Chair, AGA Diversity Committee; assistant professor of medicine, division of gastroenterology, University of Pennsylvania, Philadelphia), Karen A. Chachu, MD, PhD (assistant professor of medicine, Duke University, Durham, N.C.), Elizabeth Coss, MD (clinical assistant professor, University of Texas Health Science Center at San Antonio), Maria Cruz-Correa, MD PhD (associate professor of medicine, biochemistry and surgery, University of Puerto Rico Comprehensive Cancer Center), Lukejohn Day, MD (associate clinical professor, University of California, San Francisco), Darrell M. Gray II, MD, MPH (assistant professor of medicine, The Ohio State University Wexner Medical Center), Esi Lamouse-Smith, MD, PhD (assistant professor of pediatrics, Columbia University, New York), Antonio Mendoza Ladd, MD (assistant professor, Texas Tech University Health Sciences Center, El Paso), and Celena NuQuay (AGA staff liaison).

References

1. Projections of the Size and Composition of the U.S. Population: 2014 to 2060 Population Estimates and Projections Current Population Reports. Colby S, Ortman JM. Issued March 2015.

2. Association of American Medical Colleges 2016 Physician Specialty Databook, https://www.aamc.org/data/workforce/reports/457712/2016-specialty-databook.html.

3. Association of American Medical Colleges Diversity in the Physician Workforce: Facts and Figures 2010.

4. Deville C, Hwang WT, Burgos R. Diversity in Graduate Medical Education in the United States by Race, Ethnicity, and Sex, 2012. JAMA Intern Med. 2015;175(10):1706-8.

5. Wells AS, Fox L, Cordova-Cobo D. How Racially Diverse Schools and Classrooms Can Benefit All Students. The Century Foundation, Feb 2016. https://tcf.org/content/report/how-racially-diverse-schools-and-classrooms-can-benefit-all-students/.

6. Johnson RL, Saha S, Arbelaez JJ et al. Racial and ethnic differences in patient perceptions of bias and cultural competence in health care. J Gen Intern Med. 2004 Feb;19(2):101-10.

7. Saha S, Guiton G, Wimmers PF et al. Student body racial and ethnic composition and diversity-related outcomes in US medical schools. JAMA. 2008 Sep 10;300(10):1135-45.

8. Association of American Medical Colleges, ERAS Data. https://www.aamc.org/services/eras/stats/359278/stats.html.
 

Publications
Publications
Article Type
Sections
Disallow All Ads
Content Gating
No Gating (article Unlocked/Free)
Alternative CME
Disqus Comments
Default

Ten Financial Tips for a Worry-Free Retirement

Article Type
Changed

 

As a contract and tax attorney for physicians for over 30 years, I have reviewed many asset summaries of late-career physicians. Although most have historically strong annual incomes of $200,000 to $400,000, accumulated wealth varies tremendously. Some physicians in their 60s have a home, a small retirement plan, and little else. Others have cash equivalents of $5,000,000 or more, no debt, real estate, and other assets. In my experience, this variance usually does not relate primarily to income differences but rather spending control and financial knowledge. If you are interested in having the opportunity to retire and not worry about finding an “early bird” special at your favorite restaurant, this article provides ten tips to help you achieve that dream.

David J. Schiller
1. Fund a Roth IRA. Immediately start funding a Roth IRA. The current limit is $5,500 per calendar year. The principal and interest will grow tax-free (not tax-deferred) over decades. At your retirement age, you will have $500,000 tax-free (invested at historic rates of growth).

2. Contribute to an employer retirement plan. Contribute to your employer’s Roth 401-K or regular 401-K. Add money starting the first day you are eligible at the rate of at least 5% of your compensation. By age 35, contribute no less than 10% of your compensation up to the legal maximum. In a Roth 401-K, you will have decades of tax-free accumulation. You may also enjoy the employer matching contribution, which varies from job to job. Do not take loans on 401-K plans. If you borrow and then terminate employment before completing repayment, the borrowed funds are treated as a plan distribution, subjecting them to taxation and possibly a penalty if you are under age 59.5. If switching jobs, move your 401-K retirement plan account into an IRA; do not cash it out. If necessary, you usually can withdraw funds to make a down payment on a home or for an emergency, but plan contributions should be viewed as “tomorrow” money. You can borrow to purchase a home and to finance your children’s educations but you cannot borrow to retire.

3. Be debt-free. It is easier to accumulate wealth if you are debt-free. Mortgages, student loans, and car payments should be minimized and eliminated as quickly as possible so that available net income is used to invest both through retirement plans and on an after-tax basis. Cars should be purchased, not leased as the “tax benefit” of leasing is a myth. Leasing a car is an expensive way of borrowing money, as you are effectively purchasing only the most expensive depreciating years of the car’s useful life (the initial few years). You should also not have credit card debt at any time as credit card debt means you are spending money before you earn it. Borrowing for clothing or a vacation reflects the inability to control one’s spending.

4. Use tax-advantaged investment vehicles. Interest income on your investments is taxed at ordinary income rates, perhaps 30% or more, but dividends issued from stock or stock mutual funds are taxed at lower long-term capital gains rates. Similarly, when you sell a stock or a stock mutual fund, the appreciation is taxed at long-term capital gains rates under most circumstances. As you are able to set funds aside, make sure that you are using tax-advantaged investment vehicles.

5. Consider no-load mutual funds. When investing in the stock market or otherwise, consider no-load mutual funds such as those offered by Vanguard that do not require an “investment advisor.” Such funds do not have sales charges and save you money. The greatest chance you have of underperforming the market relates to the expenses associated with investment, more so than the particular investments selected. Since almost all advisors underperform the market, you should consider investing on your own, minimizing costs, and watching your funds grow. As a younger physician with many high-income years in front of you, a good portion of your investments should be in equities to enjoy their appreciation over decades. With bank interest rates being minuscule, there is no reasonable alternative.

6. Develop a budget. If you or your spouse has an issue with shopping or overspending, it is imperative that you develop a budget: first allocating funds to long-term savings such as a retirement plan, next to short-term savings, then to unavoidable recurring costs such as rent or mortgage, student loans, food, and discretionary expenditures. The perfect time to put this in place is when you go from the salary of a resident or fellow into a full-time job and your pay increases by multifold. Read the book The Millionaire Next Door: The Surprising Secrets of America’s Wealthy by Thomas J. Stanley and gain control, as it is easy to do otherwise with an unprecedented and significant salary jump. If you start to live on your new salary, you will never be in a position to amass wealth and retire comfortably.

7. Send your kids to public, not private school. For each of your children, would you rather pay astronomic tuition bills for 4-8 years of college or 16-20 years counting grades 1-12 in private school? When you have children approaching school age, choose an A+ school district and send your kids to public school, not private school – they will still get into competitive colleges. This can save hundreds of thousands of dollars per child.

8. Fund a 529 plan. Whether or not you currently have children, you can fund a 529 plan to enjoy tax-free growth and plan for education expenses of children or future children. If you do not have children yet, you can name yourself or a different party as the beneficiary and then change it after children are born. If you do not have children, you can either use the 529 for someone else or cash the investment and recover the money including growth/loss thereon. Trying to fund college educations out of current income is difficult and it is better to prefund than to pay back student loans over many years.

9. Draft a will. If you are married or have children or both, it is imperative that you have wills drafted so that your wishes are implemented upon your passing. Many tax advantages are available without using complicated trusts and it is important that you maintain up-to-date wills should the unforeseen occur.

10. Purchase disability and life insurance. Your most valuable financial asset is your income stream over the coming years. Protect it with adequate private disability and life insurance policies. Policies provided by your employer typically end upon termination of employment and having a portable policy is important.

These tips will help you maximize your financial position over your work life and through retirement. The best time to get on the right track is yesterday; the second best time is today. Staying in shape financially is easier than messing up and then attempting to fix it.
 

Mr. Schiller is a physician contract and tax attorney and has practiced in Norristown, Penn. for the past 30 years. He can be contacted at 610-277-5900 or www.schillerlawassociates.com or [email protected].

Publications
Sections

 

As a contract and tax attorney for physicians for over 30 years, I have reviewed many asset summaries of late-career physicians. Although most have historically strong annual incomes of $200,000 to $400,000, accumulated wealth varies tremendously. Some physicians in their 60s have a home, a small retirement plan, and little else. Others have cash equivalents of $5,000,000 or more, no debt, real estate, and other assets. In my experience, this variance usually does not relate primarily to income differences but rather spending control and financial knowledge. If you are interested in having the opportunity to retire and not worry about finding an “early bird” special at your favorite restaurant, this article provides ten tips to help you achieve that dream.

David J. Schiller
1. Fund a Roth IRA. Immediately start funding a Roth IRA. The current limit is $5,500 per calendar year. The principal and interest will grow tax-free (not tax-deferred) over decades. At your retirement age, you will have $500,000 tax-free (invested at historic rates of growth).

2. Contribute to an employer retirement plan. Contribute to your employer’s Roth 401-K or regular 401-K. Add money starting the first day you are eligible at the rate of at least 5% of your compensation. By age 35, contribute no less than 10% of your compensation up to the legal maximum. In a Roth 401-K, you will have decades of tax-free accumulation. You may also enjoy the employer matching contribution, which varies from job to job. Do not take loans on 401-K plans. If you borrow and then terminate employment before completing repayment, the borrowed funds are treated as a plan distribution, subjecting them to taxation and possibly a penalty if you are under age 59.5. If switching jobs, move your 401-K retirement plan account into an IRA; do not cash it out. If necessary, you usually can withdraw funds to make a down payment on a home or for an emergency, but plan contributions should be viewed as “tomorrow” money. You can borrow to purchase a home and to finance your children’s educations but you cannot borrow to retire.

3. Be debt-free. It is easier to accumulate wealth if you are debt-free. Mortgages, student loans, and car payments should be minimized and eliminated as quickly as possible so that available net income is used to invest both through retirement plans and on an after-tax basis. Cars should be purchased, not leased as the “tax benefit” of leasing is a myth. Leasing a car is an expensive way of borrowing money, as you are effectively purchasing only the most expensive depreciating years of the car’s useful life (the initial few years). You should also not have credit card debt at any time as credit card debt means you are spending money before you earn it. Borrowing for clothing or a vacation reflects the inability to control one’s spending.

4. Use tax-advantaged investment vehicles. Interest income on your investments is taxed at ordinary income rates, perhaps 30% or more, but dividends issued from stock or stock mutual funds are taxed at lower long-term capital gains rates. Similarly, when you sell a stock or a stock mutual fund, the appreciation is taxed at long-term capital gains rates under most circumstances. As you are able to set funds aside, make sure that you are using tax-advantaged investment vehicles.

5. Consider no-load mutual funds. When investing in the stock market or otherwise, consider no-load mutual funds such as those offered by Vanguard that do not require an “investment advisor.” Such funds do not have sales charges and save you money. The greatest chance you have of underperforming the market relates to the expenses associated with investment, more so than the particular investments selected. Since almost all advisors underperform the market, you should consider investing on your own, minimizing costs, and watching your funds grow. As a younger physician with many high-income years in front of you, a good portion of your investments should be in equities to enjoy their appreciation over decades. With bank interest rates being minuscule, there is no reasonable alternative.

6. Develop a budget. If you or your spouse has an issue with shopping or overspending, it is imperative that you develop a budget: first allocating funds to long-term savings such as a retirement plan, next to short-term savings, then to unavoidable recurring costs such as rent or mortgage, student loans, food, and discretionary expenditures. The perfect time to put this in place is when you go from the salary of a resident or fellow into a full-time job and your pay increases by multifold. Read the book The Millionaire Next Door: The Surprising Secrets of America’s Wealthy by Thomas J. Stanley and gain control, as it is easy to do otherwise with an unprecedented and significant salary jump. If you start to live on your new salary, you will never be in a position to amass wealth and retire comfortably.

7. Send your kids to public, not private school. For each of your children, would you rather pay astronomic tuition bills for 4-8 years of college or 16-20 years counting grades 1-12 in private school? When you have children approaching school age, choose an A+ school district and send your kids to public school, not private school – they will still get into competitive colleges. This can save hundreds of thousands of dollars per child.

8. Fund a 529 plan. Whether or not you currently have children, you can fund a 529 plan to enjoy tax-free growth and plan for education expenses of children or future children. If you do not have children yet, you can name yourself or a different party as the beneficiary and then change it after children are born. If you do not have children, you can either use the 529 for someone else or cash the investment and recover the money including growth/loss thereon. Trying to fund college educations out of current income is difficult and it is better to prefund than to pay back student loans over many years.

9. Draft a will. If you are married or have children or both, it is imperative that you have wills drafted so that your wishes are implemented upon your passing. Many tax advantages are available without using complicated trusts and it is important that you maintain up-to-date wills should the unforeseen occur.

10. Purchase disability and life insurance. Your most valuable financial asset is your income stream over the coming years. Protect it with adequate private disability and life insurance policies. Policies provided by your employer typically end upon termination of employment and having a portable policy is important.

These tips will help you maximize your financial position over your work life and through retirement. The best time to get on the right track is yesterday; the second best time is today. Staying in shape financially is easier than messing up and then attempting to fix it.
 

Mr. Schiller is a physician contract and tax attorney and has practiced in Norristown, Penn. for the past 30 years. He can be contacted at 610-277-5900 or www.schillerlawassociates.com or [email protected].

 

As a contract and tax attorney for physicians for over 30 years, I have reviewed many asset summaries of late-career physicians. Although most have historically strong annual incomes of $200,000 to $400,000, accumulated wealth varies tremendously. Some physicians in their 60s have a home, a small retirement plan, and little else. Others have cash equivalents of $5,000,000 or more, no debt, real estate, and other assets. In my experience, this variance usually does not relate primarily to income differences but rather spending control and financial knowledge. If you are interested in having the opportunity to retire and not worry about finding an “early bird” special at your favorite restaurant, this article provides ten tips to help you achieve that dream.

David J. Schiller
1. Fund a Roth IRA. Immediately start funding a Roth IRA. The current limit is $5,500 per calendar year. The principal and interest will grow tax-free (not tax-deferred) over decades. At your retirement age, you will have $500,000 tax-free (invested at historic rates of growth).

2. Contribute to an employer retirement plan. Contribute to your employer’s Roth 401-K or regular 401-K. Add money starting the first day you are eligible at the rate of at least 5% of your compensation. By age 35, contribute no less than 10% of your compensation up to the legal maximum. In a Roth 401-K, you will have decades of tax-free accumulation. You may also enjoy the employer matching contribution, which varies from job to job. Do not take loans on 401-K plans. If you borrow and then terminate employment before completing repayment, the borrowed funds are treated as a plan distribution, subjecting them to taxation and possibly a penalty if you are under age 59.5. If switching jobs, move your 401-K retirement plan account into an IRA; do not cash it out. If necessary, you usually can withdraw funds to make a down payment on a home or for an emergency, but plan contributions should be viewed as “tomorrow” money. You can borrow to purchase a home and to finance your children’s educations but you cannot borrow to retire.

3. Be debt-free. It is easier to accumulate wealth if you are debt-free. Mortgages, student loans, and car payments should be minimized and eliminated as quickly as possible so that available net income is used to invest both through retirement plans and on an after-tax basis. Cars should be purchased, not leased as the “tax benefit” of leasing is a myth. Leasing a car is an expensive way of borrowing money, as you are effectively purchasing only the most expensive depreciating years of the car’s useful life (the initial few years). You should also not have credit card debt at any time as credit card debt means you are spending money before you earn it. Borrowing for clothing or a vacation reflects the inability to control one’s spending.

4. Use tax-advantaged investment vehicles. Interest income on your investments is taxed at ordinary income rates, perhaps 30% or more, but dividends issued from stock or stock mutual funds are taxed at lower long-term capital gains rates. Similarly, when you sell a stock or a stock mutual fund, the appreciation is taxed at long-term capital gains rates under most circumstances. As you are able to set funds aside, make sure that you are using tax-advantaged investment vehicles.

5. Consider no-load mutual funds. When investing in the stock market or otherwise, consider no-load mutual funds such as those offered by Vanguard that do not require an “investment advisor.” Such funds do not have sales charges and save you money. The greatest chance you have of underperforming the market relates to the expenses associated with investment, more so than the particular investments selected. Since almost all advisors underperform the market, you should consider investing on your own, minimizing costs, and watching your funds grow. As a younger physician with many high-income years in front of you, a good portion of your investments should be in equities to enjoy their appreciation over decades. With bank interest rates being minuscule, there is no reasonable alternative.

6. Develop a budget. If you or your spouse has an issue with shopping or overspending, it is imperative that you develop a budget: first allocating funds to long-term savings such as a retirement plan, next to short-term savings, then to unavoidable recurring costs such as rent or mortgage, student loans, food, and discretionary expenditures. The perfect time to put this in place is when you go from the salary of a resident or fellow into a full-time job and your pay increases by multifold. Read the book The Millionaire Next Door: The Surprising Secrets of America’s Wealthy by Thomas J. Stanley and gain control, as it is easy to do otherwise with an unprecedented and significant salary jump. If you start to live on your new salary, you will never be in a position to amass wealth and retire comfortably.

7. Send your kids to public, not private school. For each of your children, would you rather pay astronomic tuition bills for 4-8 years of college or 16-20 years counting grades 1-12 in private school? When you have children approaching school age, choose an A+ school district and send your kids to public school, not private school – they will still get into competitive colleges. This can save hundreds of thousands of dollars per child.

8. Fund a 529 plan. Whether or not you currently have children, you can fund a 529 plan to enjoy tax-free growth and plan for education expenses of children or future children. If you do not have children yet, you can name yourself or a different party as the beneficiary and then change it after children are born. If you do not have children, you can either use the 529 for someone else or cash the investment and recover the money including growth/loss thereon. Trying to fund college educations out of current income is difficult and it is better to prefund than to pay back student loans over many years.

9. Draft a will. If you are married or have children or both, it is imperative that you have wills drafted so that your wishes are implemented upon your passing. Many tax advantages are available without using complicated trusts and it is important that you maintain up-to-date wills should the unforeseen occur.

10. Purchase disability and life insurance. Your most valuable financial asset is your income stream over the coming years. Protect it with adequate private disability and life insurance policies. Policies provided by your employer typically end upon termination of employment and having a portable policy is important.

These tips will help you maximize your financial position over your work life and through retirement. The best time to get on the right track is yesterday; the second best time is today. Staying in shape financially is easier than messing up and then attempting to fix it.
 

Mr. Schiller is a physician contract and tax attorney and has practiced in Norristown, Penn. for the past 30 years. He can be contacted at 610-277-5900 or www.schillerlawassociates.com or [email protected].

Publications
Publications
Article Type
Sections
Disallow All Ads
Content Gating
No Gating (article Unlocked/Free)
Alternative CME
Disqus Comments
Default