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Observations during development of an internal medicine residency training program in cardiovascular limited ultrasound examination

Although the advent of small ultraportable bedside ultrasound devices have heralded the age of the ultrasonic stethoscope,15 realizing the widespread potential of ultrasound‐assisted physical examination68 requires the creation of an imaging protocol that can be successfully taught to all physicians within the confines of accredited medical education. Prior feasibility studies of teaching internal medical residents are characterized by heterogeneity in imaging protocols, nonrandomized enrollment of a small number of trainees, and training that is short‐lived,6, 914 making their results difficult to generalize. Few data exist on the effects of sustained incorporation of a comprehensive, structured program within a conventional 3‐year internal medicine residency.

Over the past 14 years, we have developed cardiovascular limited ultrasound examination (CLUE), with the specific purpose of detecting prevalent cardiovascular pathologies that: (1) have been shown to affect morbidity and mortality in an adult population, (2) are often missed by physical examination, and (3) have been detected by medical residents who have been taught a simplified ultrasound examination. In this report, we will detail our observations regarding CLUE and its training curriculum with assessment of proficiency, program requirements, and the overall academic effect once firmly integrated into an internal medicine residency program.

METHODS

Setting and Participants

The ultrasound training program was created at Scripps Mercy Hospital San Diego Campus, a 500‐bed community hospital in San Diego, California, for integration into a 3‐year internal medicine residency program. It was accredited by the Accreditation Council for Graduate Medical Education (ACGME) and consisted of approximately 33 residents, and 23 full‐time and 82 part‐time faculty. Since 2005, all internal medicine residents have been participating in the ultrasound training program and their progress followed as a part of the ACGME Educational Innovation Project. Of the 41 consecutive graduating residents in whom performance data were collected, no resident had prior formal training in ultrasound.

Program Overview

Based upon initial studies of performing limited echo examination,1520 the following imaging protocols were combined to comprise CLUE, a brief, quick‐look two‐dimensional multi‐targeted ultrasound examination: (1) the extracranial carotid bulb for carotid atherosclerosis, (2) parasternal long‐axis view for left ventricular systolic dysfunction and left atrial enlargement, (3) apical lung views for interstitial edema, (4) basal lung views for pleural effusion, (5) a subcostal 4‐chamber view for isolated right ventricular enlargement or pericardial effusion, (6) the longitudinal view of the inferior vena cava for elevated central venous pressures, and (7) a mid‐abdominal longitudinal view for abdominal aortic aneurysm. Evidence‐basis for the exam targets and specifics of subjective diagnostic CLUE criteria (Table 1) have been published elsewhere.2130

CLUE Diagnostic Criteria and Commonly Observed Pitfalls
DiseaseDiagnostic CriteriaPitfalls
  • NOTE: The CLUE ultrasound targets are listed (left column) with the corresponding subjective diagnostic 2‐dimensional criteria (middle column) and corresponding pitfalls observed during the training program (right column). Abbreviations: AP, anterior‐posterior; CLUE, cardiovascular limited ultrasound exam; COPD, chronic obstructive pulmonary disease; FPs, false positives; IVC, inferior vena cava; LA, left atrium; LV, left ventricle; PLAX, parasternal long axis; RV, right ventricle; SN, sensitivity.

1. Carotid atheromaFocal thickened/calcified region of plaque22Reduced SN for isoechoic clot or dissection; not for use in acute neurologic syndromes
2. LV systolic dysfunctionMitral anterior leaflet tip does not approach septum (<1 cm) in diastole21, 23, 26Reduced SN for acute or apical wall motion abnormalities; FPs due to severe aortic regurgitation, mitral stenosis
3. Left atrial enlargementLA appears larger than aortic root (AP diameter) throughout the cardiac cycle21, 2426Reduced SN when LA asymmetrically enlarges (elongates); FPs due to far field artifact mistaken for posterior LA wall.
4. Lung comet‐tail artifactThree or more linear artifacts extending from pleura to the far field, moving with respiration26Reduced SN when probe not tilted to scan perpendicular to convex apical lung surface or imaging during inspiration only. Apical comets can be present in COPD with subclinical interstitial disease
5. Pleural effusionAnechoic region above the diaphragm and below lung27, 28Reduced SN for small effusions when probe not placed posterior enough. FPs of ascites or gastric fluid
6. Pericardial effusionAnechoic region seen deep to LV and above descending aorta in PLAX,15 or between the liver and RV in the subcostal view27FPs of an epicardial fat pad or right pleural effusion. A large effusion and dilated IVC are mandatory in the consideration of tamponade by the resident
7. RV enlargementSize (AP diameter) of the RV appears equal or greater than the LV29.Reduced SN due to lack of imaging during a deep inspiration or due to off‐axis imaging
8. IVC plethoraIVC AP diameter equals or exceeds the same‐level aortic diameter and fails to reduce size with respiration14, 26, 30Reduced SN when mistaking a hepatic vein for the IVC. FP when mistaking the descending aorta for a dilated IVC, particularly when IVC is collapsed.
9. Abdominal aortic aneurysmFocal dilation 1.5 the size of neighboring segment21Reduced SN due to bowel gas or mistaking a normal IVC for the aorta. FPs of cysts identified as aneurysmal disease

Two useful mnemonics were created to teach the imaging protocol. If using only the 3 MHz cardiac probe, residents were taught to work backward against the flow of blood, in regards to physiologic effects and the sequence of CLUE views. Starting in the left ventricle, systolic function was first evaluated, followed by left atrial enlargement, the presence of lung comets, then lung effusions, then right ventricular enlargement, the presence of pericardial effusion, then elevation of central venous pressures. If the high‐frequency 5 MHz linear probe was available for carotid imaging, then an additional mnemonic was remembered that atherosclerotic progression increased from top to bottom in CLUE, typified by the frequent detection of early disease in the carotid bulb, then occasional cardiac manifestations, followed by the infrequent late manifestation of an abdominal aortic aneurysm. In our practice, performance of the complete CLUE starting at the top (carotids), changing transducers to work backward in the thorax (cardiac, lung, and inferior vena cava), and finishing with the bottom (aorta) was often dependent upon equipment and linear probe availability at the point‐of‐care.

A formalized CLUE curriculum was implemented into the residency in 2006. Twelve monthly 1‐hour CLUE lectures were given per year. Most lectures were 3045 minutes in length, leaving 1530 minutes for imaging resident or patient volunteers. All forms of ultrasound devices available to the residents, including pocket‐sized, hand‐carried, cart‐based, and standard ultrasound machines, were used in this forum. To learn the fundamentals of imaging technique, the intern during the cardiology consultation month rotation was first expected to image 1030 patients in the echocardiography and vascular ultrasound labs under the tutelage of the sonographers. Once weekly, 1‐hour bedside teaching was given to junior and senior residents on the intensive care unit (ICU) and cardiology consult rotations, in a traditional case‐based format. Over the ICU month rotation, junior and senior residents could each image an additional 1030 patients, resulting in a minimum of 30 studies obtained on acutely ill patients during the ICU rotations of residency. During clinical care rotations over the 3‐year residency, all residents imaged a minimum of 30 patients (at least 10 proctored studies during their internship cardiology consultation month, 10 proctored during ICU junior year rotations, and 10 proctored during ICU senior year rotations), with some residents imaging over a hundred patients (Table 2). To assist their education in CLUE, multiple learning aides were made available, including instructional how‐to‐image videos, a 200‐page syllabus, self‐assessment tests, and an instructional web site. Overall, the independent study and performance of CLUE was encouraged, but without formal performance incentives, monitoring, or effect upon residency evaluations.

Summary of Resident Curriculum and Estimates of Hours Spent
 LectureImagingOther
  • NOTE: CLUE curriculum (lectures and bedside teaching, imaging opportunities, and extracurricular) as noted by postgraduate year as provided. Estimated hours typically observed by faculty summarized at bottom and account for excused absences due to mandatory resident hour limitations, vacations, and away rotations. Abbreviations: CHF, congestive heart failure; CLUE‐CEX, cardiovascular limited ultrasound exam‐clinical exercise; ED, emergency department; ICU, intensive care unit; PGY, postgraduate year.

PGY‐1 (intern)12 (1‐hr) conferences; Web site instruction; syllabus; 12 (1‐hr) bedside ICU roundsEcho lab imaging with 20 (10 proctored) studies on cardiology consults; outpatient cardiology clinicsResearch; imaging in ICU, CHF, and medical clinics; ED
PGY‐2 (junior)12 (1‐hr) conferences; Web site instruction; syllabus; 8 (1‐hr) bedside ICU rounds20 (10 proctored) during 2 ICU rotationsResearch; teaching others; imaging in CHF and medical clinics; ED; echo lab
PGY‐3 (senior)12 (1‐hr) conferences; Web site instruction; syllabus; 12 (1‐hr) bedside ICU rounds20 (10 proctored) during 2 ICU rotations, cardiology consults, echo labResearch; teaching others; imaging in CHF and medical clinics; ED; CLUE‐CEX
Time completed (estimate)50 hr60 cases (30 proctored) 

At our institution, the medical director of the Echocardiography and Vascular ultrasound laboratory was a cardiologist (B.J.K.) who directed the CLUE training program. The Director provided the monthly lecture series to the entire residency and was responsible for weekly 1‐hour bedside ICU rounds. If given maintenance responsibilities of weekly bedside ICU rounds (1 hour/week), monthly lecture and preparation (5 hours/month), and availability to teach the cardiology intern (3 hours/month) and maintain the Web site (4 hours/month), the program required 4 hours/week of the Director's time. The program used 3 dedicated devices: the SonoSite 180 (SonoSite, Inc, Bothell, WA), the MicroMaxx (SonoSite, Inc) and, in 2010, a pocket‐sized cardiac ultrasound stethoscope, the Vscan (GE Healthcare, Wauwatosa, WI). No patient charges were submitted for performance or interpretation of any CLUE.

Assessment and Follow‐Up

A proficiency test was performed at the end of each resident's senior year. The test, cardiovascular limited ultrasound exam‐clinical exercise (CLUE‐CEX), involved imaging any available, consenting patient and assessing the resident's technical skills by image quality, knowledge of diagnostic criteria, and ability to discuss the clinical aspects of potential findings in a question‐and‐answer oral interview format, typically requiring 2030 minutes to perform. Each resident CLUE view was rated for: (1) image quality which accounted for 44% of total exam points, (2) specific knowledge related to each view which accounted for 28% of total exam points, and (3) diagnostic accuracy of the interpretation of each view which accounted for 28% of total exam points (see Figure 1). CLUE‐CEX scores were recorded as a percentage of total possible points, normalized to the difficulty of imaging the individual patient as determined by the Director's imaging. The test encompassed performance of all 7 views, demonstrated in 2 exams employing 2 transducers (cardiac and vascular) on the same patient (Figure 1). A passing threshold had been empirically derived at >80% of the total available points, a value that: (1) required performance in all 3 categories, (2) subjectively correlated to competency when assessed by the Director, and (3) had parity with other thresholds of clinical skill assessment by faculty and in graduate education. The Director had no knowledge of non‐CLUE resident evaluations, In‐training scores, or academic performance outside of CLUE. Residents were not remanded for CLUE‐CEX failure.

Figure 1
Cardiovascular limited ultrasound exam‐clinical exercise (CLUE‐CEX) form.

The graduating class of 2011 was the first class to initially enter into an entire residency program fully immersed in the CLUE curriculum, and was therefore specifically asked to report their impression of the CLUE program after graduation through a post‐residency questionnaire. A Likert‐type scale (1 = strongly disagree, 2 = disagree, 3 = neutral, 4 = agree, 5 = strongly agree) was used to assess the perceived validity of the following statements: (1) CLUE improved my own bedside cardiovascular evaluation; and (2) I would use CLUE if ultrasound were available in my future position. Each resident was then asked if too much, not enough, or an appropriate amount of time was spent to learn CLUE, and to choose the most effective form of CLUE teaching to which they were exposed: didactic lectures, bedside ICU teaching, Web site/syllabus, and one‐to‐one training with the Director or sonographer.

Statistical Analysis

The CLUE experience was divided into 3 phases: (1) pre‐CLUE era, the 4‐year period (classes graduating 20022005) prior to the institution of the formal CLUE curriculum; (2) the 2‐year CLUE phase‐in period (classes graduating 20062007), in which portions of the residency were undergoing the 3‐year curriculum; (3) the 4‐year CLUE‐CEX era (classes graduating 20082011) when all residency classes were trained in the standardized fashion and underwent CLUE‐CEX assessment. In‐training postgraduate year‐3 (PGY‐3) scores, the result of a nationwide standardized test developed by the American College of Physicians, were used as representative of senior resident academic knowledge. A percentile rank score is provided to compare residents to nationwide data. The group of residents who had been selected to be the following year's chief residents had their CLUE‐CEX scores analyzed as a subgroup.

Data are presented as mean standard deviation and analyzed in SPSS, version 12.0 (SPSS, Inc, Chicago, IL). Linear regression was used to investigate the relationship between In‐training percentile ranks and CLUE‐CEX scores. Analysis of variance was used to determine any effect of gender and chief resident selection on CLUE‐CEX, and to assess average resident In‐training percentile ranks during the pre‐CLUE and CLUE‐CEX periods. Subset analysis of individual CLUE‐CEX scores was performed in regards to image quality, diagnostic knowledge, and interpretative skills. A value of P < 0.05 was considered significant.

RESULTS

Observations During CLUE Program Development

CLUE‐CEX scores (20082011) included data from 41 residents; 51% were male. In the class of 2009, one second‐year male resident transferred to another program for nonacademic reasons, reducing its number to 9. We observed that the impact of the CLUE program depended in part upon resident‐to‐resident teaching and required a critical mass of residents to be trained during a phase‐in period before a maximal effect could be appreciated. We observed that didactic knowledge occurred before imaging skills and remained dominant by graduation, with mean percentile CLUE‐CEX scores for image quality, knowledge, and interpretative accuracy at 82% 5%, 91% 3%, and 91% 8%, respectively. Residents typically found apical lung imaging the easiest to perform (CLUE‐CEX score of 89% 19%), followed by carotid (84% 18%), inferior vena cava (IVC) imaging (84% 26%), screening for abdominal aortic aneurysm (AAA) (83% 2 4%), parasternal long‐axis (79% 30%), and subcostal cardiac 4‐chamber imaging (73% 33%). Each view had technical and diagnostic pitfalls that were noted during resident practice (see Table 1), resulting in changes in our teaching and case review in subsequent years.

Residency and CLUE Performance

In attempting to achieve a CLUE proficiency score of >80% on the CLUE‐CEX in their graduating year, 8/41 (19.5%) senior residents failed. In these 8 residents, imaging quality, knowledge, and interpretative accuracy were all depressed: 55% 19%, 79% 11%, and 75% 11%, respectively. Two of these 8 had been selected as future chief residents over the 4‐year period, positions typically awarded to 2 residents per graduating year. The performance of the residents is seen in Table 3. The CLUE program did not exert a negative effect upon the academic performance of the residency, as evidenced by the lack of a significant difference in the Pre‐CLUE, 2‐year CLUE, and CLUE‐CEX periods in regards to average resident In‐training percentile rank scores (67.5 20.1, 62.3 20.5, 69.4 16.9, respectively; P = 0.37).

Resident Performance
Time Era (Year of Graduation)nFail RateCLUE‐CEX (Mean SD)Resident IT Percentile Rank (Mean SD) (Range)
  • NOTE: Table shows mean standard deviation of CLUE‐CEX scores and resident In‐training percentile rank which represents the average of the residents' national percentile ranks of their In‐training PGY‐3 total scores during the corresponding time (Pre‐CLUE 4 years, CLUE phase‐in 2 years, CLUE‐CEX 4 years). Fail rate represents the % of residents who did not pass the CLUE‐CEX (80% correct criterion). Yearly data is listed for each of the CLUE‐CEX years, 20082011. Year denotes the year of graduation. Abbreviations: CLUE‐CEX, cardiovascular limited ultrasound exam‐clinical exercise; IT, In‐training; PGY, postgraduate year; SD, standard deviation.

Pre‐CLUE (20022005)39  67.5 20.1 (2099)
Phase‐in CLUE (20062007)19  62.3 20.5 (2097)
CLUE‐CEX (20082011)4119%87.4 11.969.4 16.9 (3499)
Year 20081136%84.3 13.974.7 17.9 (4599)
Year 2009911%89.1 7.073.0 16.6 (3493)
Year 20101030%84.2 16.957.1 12.7 (4287)
Year 2011110%92.1 5.772.4 15.9 (3499)

Figure 2 shows the relationship between CLUE‐CEX scores and In‐training PGY‐3 scores. There was no significant relationship between resident academic performance and CLUE capabilities (r = 0.05, P = 0.75). Similarly, chief resident performance (n = 14) was not significantly associated with CLUE‐CEX scores (r = 0.15, P = 0.37), nor was male gender (P = 0.07). Approximately one‐half (49%) of the residents in the 4‐year CLUE‐CEX era entered fellowships, unchanged from historic rates, with only 1 resident during this era entering into a cardiology fellowship.

Figure 2
Relationship between CLUE and academic performance. graph of CLUE‐CEX versus In‐training PGY‐3 percentile ranks. Trendline is shown (r = 0.051, P = 0.75) and demonstrates no significant correlation. Abbreviations: CLUE‐CEX, cardiovascular limited ultrasound exam‐clinical exercise; PGY‐3, postgraduate year‐3.

The Likert‐type questionnaire was returned by 11/11 graduating residents in 2011. Mean score of 4.3 0.6 (range: 35), with 6/11 responding agree, was given for the statement of whether CLUE improved the resident's own bedside exam. A score of 4.5 0.7 (range: 35), with 7/11 responding strongly agree, was given for whether the resident would use CLUE in the future if ultrasound were available. The majority (9/11) of residents felt that the time spent on CLUE was appropriate, with 2 residents responding not enough. Residents ranked one‐to‐one training with the Director(n = 6), followed by bedside ICU rounds (n = 5) as the preferred teaching methods to learn CLUE.

DISCUSSION

We report the experience of enrolling 6 consecutive classes, in an internal medicine residency, to test the feasibility of incorporating ongoing training in a specific, evidence‐based cardiovascular limited ultrasound examination within an already existing 3‐year curriculum. Using unbiased and complete enrollment, we found that residents who perform well on standardized academic testing or who are selected as chief residents do not necessarily perform more competently in CLUE, and that a significant overall initial resident failure rate can be anticipated. By questionnaire, residents felt confident in using the technique to improve their future bedside exams.

Burgeoning interest in the limited or focused application of ultrasound during bedside evaluation has already resulted in the incorporation of ultrasound training into emergency medicine residencies and critical care fellowships, with minimal standardization on curriculum, teaching methodology, or competency requirements. Given the multiple subspecialty applications for ultrasound, the potential exists of excessive diversity in bedside ultrasound practice, weakening the development of a single, simplified exam technique as a clinical tool for all physicians.31 Prior feasibility studies914 have evaluated the learning curve of internal medicine or primary care residents in performing various limited exams, but have not provided the rationale regarding the imaging protocols, the methods used for teaching, and the assessment of the program results over a sustained period of time. Furthermore, prior studies have not randomized subject trainees, likely resulting in the selected enrollment of highly motivated or skilled residents who want to perform a particular technique or have a bias to learn it. Our reported 19% unremanded failure rate on CLUE‐CEX will likely be more reflective of the general experience when initially integrating entire classes of internal medicine residents into a standard curriculum. The feasibility of introducing ultrasound at an earlier stage than residency may improve familiarity with the modality, and a 4‐year medical‐student curriculum has been recently described.32 Although introduction in medical school could allow for more adept and specific clinical training during residency, the optimal time for education in bedside ultrasound remains unclear.

Critical to the development of our program was the necessity to commit to teaching a single exam, the CLUE. We derived CLUE to quickly screen for important targets that had evidence‐basis to affect outcome, such as manifestations of subclinical atherosclerosis or chamber enlargement due to elevated filling pressures. Subsequent CLUE outcome studies have demonstrated diagnostic accuracy and prognostic value in its components,18, 26, 29, 30 and an effect upon medical decision‐making,21 even when performed by briefly trained novices.18, 21, 30 It is anticipated that this cardiovascular examination will later expand to a more advanced version or become a component of a full‐body ultrasound‐assisted physical. Therefore, evidence‐basis and brevity governed the development of a practical and teachable fundamental CLUE, and our skill assessment results are likely specific to CLUE itself.

This report contains primarily observations noted during the development of our program, written in retrospect with emphasis on real world feasibility. It was not a rigorous evaluation of specific ultrasound teaching methods. We found that training is feasible, at modest costs, when existing in‐hospital resources are utilized and include a part‐time faculty appointment and shared devices. Training the sonographers to perform CLUE as a part of the standard echocardiogram was a trivial task, but created the great benefit of being able to retrospectively review both the CLUE and formal echo in case review and teaching. Monthly CLUE lectures in the daily noon conference docket, and the use of the cardiology consultation and ICU rotations, allowed integration of the CLUE curriculum into preexisting venues and persistent practice opportunities within the residency. To prevent bias, we intentionally did not track, bring attention to, or incentivize resident performance in CLUE over any other topic; therefore, we can only approximate lecture and bedside teaching hours spent by each resident in light of detractions due to residency hour restrictions, vacations, and away rotations (Table 2). The CLUE‐CEX, although subject to the biases of any subjective resident skill assessment, was easily accomplished using a single form and faculty member, and was an efficient tool for program feedback and development.

In conclusion, we report the feasibility of sustained incorporation of an ultrasound training program in an internal medicine residency. We await studies regarding clinical outcome and validation of similar experiences in larger, multicenter programs.

Acknowledgements

The authors acknowledge the sonographers of the Scripps Mercy Cardiovascular Ultrasound Laboratory and Dudie Keane, for their dedication and assistance in the implementation of the CLUE program.

Disclosure: Nothing to report.

Note: The correction that was made, was the text in Fig. 1 and Fig. 2 were reversed. This article was published online on May 17, 2012. An error was subsequently identified. This notice is included in the online and print versions to indicate that both have been corrected on May 22, 2012.

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Although the advent of small ultraportable bedside ultrasound devices have heralded the age of the ultrasonic stethoscope,15 realizing the widespread potential of ultrasound‐assisted physical examination68 requires the creation of an imaging protocol that can be successfully taught to all physicians within the confines of accredited medical education. Prior feasibility studies of teaching internal medical residents are characterized by heterogeneity in imaging protocols, nonrandomized enrollment of a small number of trainees, and training that is short‐lived,6, 914 making their results difficult to generalize. Few data exist on the effects of sustained incorporation of a comprehensive, structured program within a conventional 3‐year internal medicine residency.

Over the past 14 years, we have developed cardiovascular limited ultrasound examination (CLUE), with the specific purpose of detecting prevalent cardiovascular pathologies that: (1) have been shown to affect morbidity and mortality in an adult population, (2) are often missed by physical examination, and (3) have been detected by medical residents who have been taught a simplified ultrasound examination. In this report, we will detail our observations regarding CLUE and its training curriculum with assessment of proficiency, program requirements, and the overall academic effect once firmly integrated into an internal medicine residency program.

METHODS

Setting and Participants

The ultrasound training program was created at Scripps Mercy Hospital San Diego Campus, a 500‐bed community hospital in San Diego, California, for integration into a 3‐year internal medicine residency program. It was accredited by the Accreditation Council for Graduate Medical Education (ACGME) and consisted of approximately 33 residents, and 23 full‐time and 82 part‐time faculty. Since 2005, all internal medicine residents have been participating in the ultrasound training program and their progress followed as a part of the ACGME Educational Innovation Project. Of the 41 consecutive graduating residents in whom performance data were collected, no resident had prior formal training in ultrasound.

Program Overview

Based upon initial studies of performing limited echo examination,1520 the following imaging protocols were combined to comprise CLUE, a brief, quick‐look two‐dimensional multi‐targeted ultrasound examination: (1) the extracranial carotid bulb for carotid atherosclerosis, (2) parasternal long‐axis view for left ventricular systolic dysfunction and left atrial enlargement, (3) apical lung views for interstitial edema, (4) basal lung views for pleural effusion, (5) a subcostal 4‐chamber view for isolated right ventricular enlargement or pericardial effusion, (6) the longitudinal view of the inferior vena cava for elevated central venous pressures, and (7) a mid‐abdominal longitudinal view for abdominal aortic aneurysm. Evidence‐basis for the exam targets and specifics of subjective diagnostic CLUE criteria (Table 1) have been published elsewhere.2130

CLUE Diagnostic Criteria and Commonly Observed Pitfalls
DiseaseDiagnostic CriteriaPitfalls
  • NOTE: The CLUE ultrasound targets are listed (left column) with the corresponding subjective diagnostic 2‐dimensional criteria (middle column) and corresponding pitfalls observed during the training program (right column). Abbreviations: AP, anterior‐posterior; CLUE, cardiovascular limited ultrasound exam; COPD, chronic obstructive pulmonary disease; FPs, false positives; IVC, inferior vena cava; LA, left atrium; LV, left ventricle; PLAX, parasternal long axis; RV, right ventricle; SN, sensitivity.

1. Carotid atheromaFocal thickened/calcified region of plaque22Reduced SN for isoechoic clot or dissection; not for use in acute neurologic syndromes
2. LV systolic dysfunctionMitral anterior leaflet tip does not approach septum (<1 cm) in diastole21, 23, 26Reduced SN for acute or apical wall motion abnormalities; FPs due to severe aortic regurgitation, mitral stenosis
3. Left atrial enlargementLA appears larger than aortic root (AP diameter) throughout the cardiac cycle21, 2426Reduced SN when LA asymmetrically enlarges (elongates); FPs due to far field artifact mistaken for posterior LA wall.
4. Lung comet‐tail artifactThree or more linear artifacts extending from pleura to the far field, moving with respiration26Reduced SN when probe not tilted to scan perpendicular to convex apical lung surface or imaging during inspiration only. Apical comets can be present in COPD with subclinical interstitial disease
5. Pleural effusionAnechoic region above the diaphragm and below lung27, 28Reduced SN for small effusions when probe not placed posterior enough. FPs of ascites or gastric fluid
6. Pericardial effusionAnechoic region seen deep to LV and above descending aorta in PLAX,15 or between the liver and RV in the subcostal view27FPs of an epicardial fat pad or right pleural effusion. A large effusion and dilated IVC are mandatory in the consideration of tamponade by the resident
7. RV enlargementSize (AP diameter) of the RV appears equal or greater than the LV29.Reduced SN due to lack of imaging during a deep inspiration or due to off‐axis imaging
8. IVC plethoraIVC AP diameter equals or exceeds the same‐level aortic diameter and fails to reduce size with respiration14, 26, 30Reduced SN when mistaking a hepatic vein for the IVC. FP when mistaking the descending aorta for a dilated IVC, particularly when IVC is collapsed.
9. Abdominal aortic aneurysmFocal dilation 1.5 the size of neighboring segment21Reduced SN due to bowel gas or mistaking a normal IVC for the aorta. FPs of cysts identified as aneurysmal disease

Two useful mnemonics were created to teach the imaging protocol. If using only the 3 MHz cardiac probe, residents were taught to work backward against the flow of blood, in regards to physiologic effects and the sequence of CLUE views. Starting in the left ventricle, systolic function was first evaluated, followed by left atrial enlargement, the presence of lung comets, then lung effusions, then right ventricular enlargement, the presence of pericardial effusion, then elevation of central venous pressures. If the high‐frequency 5 MHz linear probe was available for carotid imaging, then an additional mnemonic was remembered that atherosclerotic progression increased from top to bottom in CLUE, typified by the frequent detection of early disease in the carotid bulb, then occasional cardiac manifestations, followed by the infrequent late manifestation of an abdominal aortic aneurysm. In our practice, performance of the complete CLUE starting at the top (carotids), changing transducers to work backward in the thorax (cardiac, lung, and inferior vena cava), and finishing with the bottom (aorta) was often dependent upon equipment and linear probe availability at the point‐of‐care.

A formalized CLUE curriculum was implemented into the residency in 2006. Twelve monthly 1‐hour CLUE lectures were given per year. Most lectures were 3045 minutes in length, leaving 1530 minutes for imaging resident or patient volunteers. All forms of ultrasound devices available to the residents, including pocket‐sized, hand‐carried, cart‐based, and standard ultrasound machines, were used in this forum. To learn the fundamentals of imaging technique, the intern during the cardiology consultation month rotation was first expected to image 1030 patients in the echocardiography and vascular ultrasound labs under the tutelage of the sonographers. Once weekly, 1‐hour bedside teaching was given to junior and senior residents on the intensive care unit (ICU) and cardiology consult rotations, in a traditional case‐based format. Over the ICU month rotation, junior and senior residents could each image an additional 1030 patients, resulting in a minimum of 30 studies obtained on acutely ill patients during the ICU rotations of residency. During clinical care rotations over the 3‐year residency, all residents imaged a minimum of 30 patients (at least 10 proctored studies during their internship cardiology consultation month, 10 proctored during ICU junior year rotations, and 10 proctored during ICU senior year rotations), with some residents imaging over a hundred patients (Table 2). To assist their education in CLUE, multiple learning aides were made available, including instructional how‐to‐image videos, a 200‐page syllabus, self‐assessment tests, and an instructional web site. Overall, the independent study and performance of CLUE was encouraged, but without formal performance incentives, monitoring, or effect upon residency evaluations.

Summary of Resident Curriculum and Estimates of Hours Spent
 LectureImagingOther
  • NOTE: CLUE curriculum (lectures and bedside teaching, imaging opportunities, and extracurricular) as noted by postgraduate year as provided. Estimated hours typically observed by faculty summarized at bottom and account for excused absences due to mandatory resident hour limitations, vacations, and away rotations. Abbreviations: CHF, congestive heart failure; CLUE‐CEX, cardiovascular limited ultrasound exam‐clinical exercise; ED, emergency department; ICU, intensive care unit; PGY, postgraduate year.

PGY‐1 (intern)12 (1‐hr) conferences; Web site instruction; syllabus; 12 (1‐hr) bedside ICU roundsEcho lab imaging with 20 (10 proctored) studies on cardiology consults; outpatient cardiology clinicsResearch; imaging in ICU, CHF, and medical clinics; ED
PGY‐2 (junior)12 (1‐hr) conferences; Web site instruction; syllabus; 8 (1‐hr) bedside ICU rounds20 (10 proctored) during 2 ICU rotationsResearch; teaching others; imaging in CHF and medical clinics; ED; echo lab
PGY‐3 (senior)12 (1‐hr) conferences; Web site instruction; syllabus; 12 (1‐hr) bedside ICU rounds20 (10 proctored) during 2 ICU rotations, cardiology consults, echo labResearch; teaching others; imaging in CHF and medical clinics; ED; CLUE‐CEX
Time completed (estimate)50 hr60 cases (30 proctored) 

At our institution, the medical director of the Echocardiography and Vascular ultrasound laboratory was a cardiologist (B.J.K.) who directed the CLUE training program. The Director provided the monthly lecture series to the entire residency and was responsible for weekly 1‐hour bedside ICU rounds. If given maintenance responsibilities of weekly bedside ICU rounds (1 hour/week), monthly lecture and preparation (5 hours/month), and availability to teach the cardiology intern (3 hours/month) and maintain the Web site (4 hours/month), the program required 4 hours/week of the Director's time. The program used 3 dedicated devices: the SonoSite 180 (SonoSite, Inc, Bothell, WA), the MicroMaxx (SonoSite, Inc) and, in 2010, a pocket‐sized cardiac ultrasound stethoscope, the Vscan (GE Healthcare, Wauwatosa, WI). No patient charges were submitted for performance or interpretation of any CLUE.

Assessment and Follow‐Up

A proficiency test was performed at the end of each resident's senior year. The test, cardiovascular limited ultrasound exam‐clinical exercise (CLUE‐CEX), involved imaging any available, consenting patient and assessing the resident's technical skills by image quality, knowledge of diagnostic criteria, and ability to discuss the clinical aspects of potential findings in a question‐and‐answer oral interview format, typically requiring 2030 minutes to perform. Each resident CLUE view was rated for: (1) image quality which accounted for 44% of total exam points, (2) specific knowledge related to each view which accounted for 28% of total exam points, and (3) diagnostic accuracy of the interpretation of each view which accounted for 28% of total exam points (see Figure 1). CLUE‐CEX scores were recorded as a percentage of total possible points, normalized to the difficulty of imaging the individual patient as determined by the Director's imaging. The test encompassed performance of all 7 views, demonstrated in 2 exams employing 2 transducers (cardiac and vascular) on the same patient (Figure 1). A passing threshold had been empirically derived at >80% of the total available points, a value that: (1) required performance in all 3 categories, (2) subjectively correlated to competency when assessed by the Director, and (3) had parity with other thresholds of clinical skill assessment by faculty and in graduate education. The Director had no knowledge of non‐CLUE resident evaluations, In‐training scores, or academic performance outside of CLUE. Residents were not remanded for CLUE‐CEX failure.

Figure 1
Cardiovascular limited ultrasound exam‐clinical exercise (CLUE‐CEX) form.

The graduating class of 2011 was the first class to initially enter into an entire residency program fully immersed in the CLUE curriculum, and was therefore specifically asked to report their impression of the CLUE program after graduation through a post‐residency questionnaire. A Likert‐type scale (1 = strongly disagree, 2 = disagree, 3 = neutral, 4 = agree, 5 = strongly agree) was used to assess the perceived validity of the following statements: (1) CLUE improved my own bedside cardiovascular evaluation; and (2) I would use CLUE if ultrasound were available in my future position. Each resident was then asked if too much, not enough, or an appropriate amount of time was spent to learn CLUE, and to choose the most effective form of CLUE teaching to which they were exposed: didactic lectures, bedside ICU teaching, Web site/syllabus, and one‐to‐one training with the Director or sonographer.

Statistical Analysis

The CLUE experience was divided into 3 phases: (1) pre‐CLUE era, the 4‐year period (classes graduating 20022005) prior to the institution of the formal CLUE curriculum; (2) the 2‐year CLUE phase‐in period (classes graduating 20062007), in which portions of the residency were undergoing the 3‐year curriculum; (3) the 4‐year CLUE‐CEX era (classes graduating 20082011) when all residency classes were trained in the standardized fashion and underwent CLUE‐CEX assessment. In‐training postgraduate year‐3 (PGY‐3) scores, the result of a nationwide standardized test developed by the American College of Physicians, were used as representative of senior resident academic knowledge. A percentile rank score is provided to compare residents to nationwide data. The group of residents who had been selected to be the following year's chief residents had their CLUE‐CEX scores analyzed as a subgroup.

Data are presented as mean standard deviation and analyzed in SPSS, version 12.0 (SPSS, Inc, Chicago, IL). Linear regression was used to investigate the relationship between In‐training percentile ranks and CLUE‐CEX scores. Analysis of variance was used to determine any effect of gender and chief resident selection on CLUE‐CEX, and to assess average resident In‐training percentile ranks during the pre‐CLUE and CLUE‐CEX periods. Subset analysis of individual CLUE‐CEX scores was performed in regards to image quality, diagnostic knowledge, and interpretative skills. A value of P < 0.05 was considered significant.

RESULTS

Observations During CLUE Program Development

CLUE‐CEX scores (20082011) included data from 41 residents; 51% were male. In the class of 2009, one second‐year male resident transferred to another program for nonacademic reasons, reducing its number to 9. We observed that the impact of the CLUE program depended in part upon resident‐to‐resident teaching and required a critical mass of residents to be trained during a phase‐in period before a maximal effect could be appreciated. We observed that didactic knowledge occurred before imaging skills and remained dominant by graduation, with mean percentile CLUE‐CEX scores for image quality, knowledge, and interpretative accuracy at 82% 5%, 91% 3%, and 91% 8%, respectively. Residents typically found apical lung imaging the easiest to perform (CLUE‐CEX score of 89% 19%), followed by carotid (84% 18%), inferior vena cava (IVC) imaging (84% 26%), screening for abdominal aortic aneurysm (AAA) (83% 2 4%), parasternal long‐axis (79% 30%), and subcostal cardiac 4‐chamber imaging (73% 33%). Each view had technical and diagnostic pitfalls that were noted during resident practice (see Table 1), resulting in changes in our teaching and case review in subsequent years.

Residency and CLUE Performance

In attempting to achieve a CLUE proficiency score of >80% on the CLUE‐CEX in their graduating year, 8/41 (19.5%) senior residents failed. In these 8 residents, imaging quality, knowledge, and interpretative accuracy were all depressed: 55% 19%, 79% 11%, and 75% 11%, respectively. Two of these 8 had been selected as future chief residents over the 4‐year period, positions typically awarded to 2 residents per graduating year. The performance of the residents is seen in Table 3. The CLUE program did not exert a negative effect upon the academic performance of the residency, as evidenced by the lack of a significant difference in the Pre‐CLUE, 2‐year CLUE, and CLUE‐CEX periods in regards to average resident In‐training percentile rank scores (67.5 20.1, 62.3 20.5, 69.4 16.9, respectively; P = 0.37).

Resident Performance
Time Era (Year of Graduation)nFail RateCLUE‐CEX (Mean SD)Resident IT Percentile Rank (Mean SD) (Range)
  • NOTE: Table shows mean standard deviation of CLUE‐CEX scores and resident In‐training percentile rank which represents the average of the residents' national percentile ranks of their In‐training PGY‐3 total scores during the corresponding time (Pre‐CLUE 4 years, CLUE phase‐in 2 years, CLUE‐CEX 4 years). Fail rate represents the % of residents who did not pass the CLUE‐CEX (80% correct criterion). Yearly data is listed for each of the CLUE‐CEX years, 20082011. Year denotes the year of graduation. Abbreviations: CLUE‐CEX, cardiovascular limited ultrasound exam‐clinical exercise; IT, In‐training; PGY, postgraduate year; SD, standard deviation.

Pre‐CLUE (20022005)39  67.5 20.1 (2099)
Phase‐in CLUE (20062007)19  62.3 20.5 (2097)
CLUE‐CEX (20082011)4119%87.4 11.969.4 16.9 (3499)
Year 20081136%84.3 13.974.7 17.9 (4599)
Year 2009911%89.1 7.073.0 16.6 (3493)
Year 20101030%84.2 16.957.1 12.7 (4287)
Year 2011110%92.1 5.772.4 15.9 (3499)

Figure 2 shows the relationship between CLUE‐CEX scores and In‐training PGY‐3 scores. There was no significant relationship between resident academic performance and CLUE capabilities (r = 0.05, P = 0.75). Similarly, chief resident performance (n = 14) was not significantly associated with CLUE‐CEX scores (r = 0.15, P = 0.37), nor was male gender (P = 0.07). Approximately one‐half (49%) of the residents in the 4‐year CLUE‐CEX era entered fellowships, unchanged from historic rates, with only 1 resident during this era entering into a cardiology fellowship.

Figure 2
Relationship between CLUE and academic performance. graph of CLUE‐CEX versus In‐training PGY‐3 percentile ranks. Trendline is shown (r = 0.051, P = 0.75) and demonstrates no significant correlation. Abbreviations: CLUE‐CEX, cardiovascular limited ultrasound exam‐clinical exercise; PGY‐3, postgraduate year‐3.

The Likert‐type questionnaire was returned by 11/11 graduating residents in 2011. Mean score of 4.3 0.6 (range: 35), with 6/11 responding agree, was given for the statement of whether CLUE improved the resident's own bedside exam. A score of 4.5 0.7 (range: 35), with 7/11 responding strongly agree, was given for whether the resident would use CLUE in the future if ultrasound were available. The majority (9/11) of residents felt that the time spent on CLUE was appropriate, with 2 residents responding not enough. Residents ranked one‐to‐one training with the Director(n = 6), followed by bedside ICU rounds (n = 5) as the preferred teaching methods to learn CLUE.

DISCUSSION

We report the experience of enrolling 6 consecutive classes, in an internal medicine residency, to test the feasibility of incorporating ongoing training in a specific, evidence‐based cardiovascular limited ultrasound examination within an already existing 3‐year curriculum. Using unbiased and complete enrollment, we found that residents who perform well on standardized academic testing or who are selected as chief residents do not necessarily perform more competently in CLUE, and that a significant overall initial resident failure rate can be anticipated. By questionnaire, residents felt confident in using the technique to improve their future bedside exams.

Burgeoning interest in the limited or focused application of ultrasound during bedside evaluation has already resulted in the incorporation of ultrasound training into emergency medicine residencies and critical care fellowships, with minimal standardization on curriculum, teaching methodology, or competency requirements. Given the multiple subspecialty applications for ultrasound, the potential exists of excessive diversity in bedside ultrasound practice, weakening the development of a single, simplified exam technique as a clinical tool for all physicians.31 Prior feasibility studies914 have evaluated the learning curve of internal medicine or primary care residents in performing various limited exams, but have not provided the rationale regarding the imaging protocols, the methods used for teaching, and the assessment of the program results over a sustained period of time. Furthermore, prior studies have not randomized subject trainees, likely resulting in the selected enrollment of highly motivated or skilled residents who want to perform a particular technique or have a bias to learn it. Our reported 19% unremanded failure rate on CLUE‐CEX will likely be more reflective of the general experience when initially integrating entire classes of internal medicine residents into a standard curriculum. The feasibility of introducing ultrasound at an earlier stage than residency may improve familiarity with the modality, and a 4‐year medical‐student curriculum has been recently described.32 Although introduction in medical school could allow for more adept and specific clinical training during residency, the optimal time for education in bedside ultrasound remains unclear.

Critical to the development of our program was the necessity to commit to teaching a single exam, the CLUE. We derived CLUE to quickly screen for important targets that had evidence‐basis to affect outcome, such as manifestations of subclinical atherosclerosis or chamber enlargement due to elevated filling pressures. Subsequent CLUE outcome studies have demonstrated diagnostic accuracy and prognostic value in its components,18, 26, 29, 30 and an effect upon medical decision‐making,21 even when performed by briefly trained novices.18, 21, 30 It is anticipated that this cardiovascular examination will later expand to a more advanced version or become a component of a full‐body ultrasound‐assisted physical. Therefore, evidence‐basis and brevity governed the development of a practical and teachable fundamental CLUE, and our skill assessment results are likely specific to CLUE itself.

This report contains primarily observations noted during the development of our program, written in retrospect with emphasis on real world feasibility. It was not a rigorous evaluation of specific ultrasound teaching methods. We found that training is feasible, at modest costs, when existing in‐hospital resources are utilized and include a part‐time faculty appointment and shared devices. Training the sonographers to perform CLUE as a part of the standard echocardiogram was a trivial task, but created the great benefit of being able to retrospectively review both the CLUE and formal echo in case review and teaching. Monthly CLUE lectures in the daily noon conference docket, and the use of the cardiology consultation and ICU rotations, allowed integration of the CLUE curriculum into preexisting venues and persistent practice opportunities within the residency. To prevent bias, we intentionally did not track, bring attention to, or incentivize resident performance in CLUE over any other topic; therefore, we can only approximate lecture and bedside teaching hours spent by each resident in light of detractions due to residency hour restrictions, vacations, and away rotations (Table 2). The CLUE‐CEX, although subject to the biases of any subjective resident skill assessment, was easily accomplished using a single form and faculty member, and was an efficient tool for program feedback and development.

In conclusion, we report the feasibility of sustained incorporation of an ultrasound training program in an internal medicine residency. We await studies regarding clinical outcome and validation of similar experiences in larger, multicenter programs.

Acknowledgements

The authors acknowledge the sonographers of the Scripps Mercy Cardiovascular Ultrasound Laboratory and Dudie Keane, for their dedication and assistance in the implementation of the CLUE program.

Disclosure: Nothing to report.

Note: The correction that was made, was the text in Fig. 1 and Fig. 2 were reversed. This article was published online on May 17, 2012. An error was subsequently identified. This notice is included in the online and print versions to indicate that both have been corrected on May 22, 2012.

Although the advent of small ultraportable bedside ultrasound devices have heralded the age of the ultrasonic stethoscope,15 realizing the widespread potential of ultrasound‐assisted physical examination68 requires the creation of an imaging protocol that can be successfully taught to all physicians within the confines of accredited medical education. Prior feasibility studies of teaching internal medical residents are characterized by heterogeneity in imaging protocols, nonrandomized enrollment of a small number of trainees, and training that is short‐lived,6, 914 making their results difficult to generalize. Few data exist on the effects of sustained incorporation of a comprehensive, structured program within a conventional 3‐year internal medicine residency.

Over the past 14 years, we have developed cardiovascular limited ultrasound examination (CLUE), with the specific purpose of detecting prevalent cardiovascular pathologies that: (1) have been shown to affect morbidity and mortality in an adult population, (2) are often missed by physical examination, and (3) have been detected by medical residents who have been taught a simplified ultrasound examination. In this report, we will detail our observations regarding CLUE and its training curriculum with assessment of proficiency, program requirements, and the overall academic effect once firmly integrated into an internal medicine residency program.

METHODS

Setting and Participants

The ultrasound training program was created at Scripps Mercy Hospital San Diego Campus, a 500‐bed community hospital in San Diego, California, for integration into a 3‐year internal medicine residency program. It was accredited by the Accreditation Council for Graduate Medical Education (ACGME) and consisted of approximately 33 residents, and 23 full‐time and 82 part‐time faculty. Since 2005, all internal medicine residents have been participating in the ultrasound training program and their progress followed as a part of the ACGME Educational Innovation Project. Of the 41 consecutive graduating residents in whom performance data were collected, no resident had prior formal training in ultrasound.

Program Overview

Based upon initial studies of performing limited echo examination,1520 the following imaging protocols were combined to comprise CLUE, a brief, quick‐look two‐dimensional multi‐targeted ultrasound examination: (1) the extracranial carotid bulb for carotid atherosclerosis, (2) parasternal long‐axis view for left ventricular systolic dysfunction and left atrial enlargement, (3) apical lung views for interstitial edema, (4) basal lung views for pleural effusion, (5) a subcostal 4‐chamber view for isolated right ventricular enlargement or pericardial effusion, (6) the longitudinal view of the inferior vena cava for elevated central venous pressures, and (7) a mid‐abdominal longitudinal view for abdominal aortic aneurysm. Evidence‐basis for the exam targets and specifics of subjective diagnostic CLUE criteria (Table 1) have been published elsewhere.2130

CLUE Diagnostic Criteria and Commonly Observed Pitfalls
DiseaseDiagnostic CriteriaPitfalls
  • NOTE: The CLUE ultrasound targets are listed (left column) with the corresponding subjective diagnostic 2‐dimensional criteria (middle column) and corresponding pitfalls observed during the training program (right column). Abbreviations: AP, anterior‐posterior; CLUE, cardiovascular limited ultrasound exam; COPD, chronic obstructive pulmonary disease; FPs, false positives; IVC, inferior vena cava; LA, left atrium; LV, left ventricle; PLAX, parasternal long axis; RV, right ventricle; SN, sensitivity.

1. Carotid atheromaFocal thickened/calcified region of plaque22Reduced SN for isoechoic clot or dissection; not for use in acute neurologic syndromes
2. LV systolic dysfunctionMitral anterior leaflet tip does not approach septum (<1 cm) in diastole21, 23, 26Reduced SN for acute or apical wall motion abnormalities; FPs due to severe aortic regurgitation, mitral stenosis
3. Left atrial enlargementLA appears larger than aortic root (AP diameter) throughout the cardiac cycle21, 2426Reduced SN when LA asymmetrically enlarges (elongates); FPs due to far field artifact mistaken for posterior LA wall.
4. Lung comet‐tail artifactThree or more linear artifacts extending from pleura to the far field, moving with respiration26Reduced SN when probe not tilted to scan perpendicular to convex apical lung surface or imaging during inspiration only. Apical comets can be present in COPD with subclinical interstitial disease
5. Pleural effusionAnechoic region above the diaphragm and below lung27, 28Reduced SN for small effusions when probe not placed posterior enough. FPs of ascites or gastric fluid
6. Pericardial effusionAnechoic region seen deep to LV and above descending aorta in PLAX,15 or between the liver and RV in the subcostal view27FPs of an epicardial fat pad or right pleural effusion. A large effusion and dilated IVC are mandatory in the consideration of tamponade by the resident
7. RV enlargementSize (AP diameter) of the RV appears equal or greater than the LV29.Reduced SN due to lack of imaging during a deep inspiration or due to off‐axis imaging
8. IVC plethoraIVC AP diameter equals or exceeds the same‐level aortic diameter and fails to reduce size with respiration14, 26, 30Reduced SN when mistaking a hepatic vein for the IVC. FP when mistaking the descending aorta for a dilated IVC, particularly when IVC is collapsed.
9. Abdominal aortic aneurysmFocal dilation 1.5 the size of neighboring segment21Reduced SN due to bowel gas or mistaking a normal IVC for the aorta. FPs of cysts identified as aneurysmal disease

Two useful mnemonics were created to teach the imaging protocol. If using only the 3 MHz cardiac probe, residents were taught to work backward against the flow of blood, in regards to physiologic effects and the sequence of CLUE views. Starting in the left ventricle, systolic function was first evaluated, followed by left atrial enlargement, the presence of lung comets, then lung effusions, then right ventricular enlargement, the presence of pericardial effusion, then elevation of central venous pressures. If the high‐frequency 5 MHz linear probe was available for carotid imaging, then an additional mnemonic was remembered that atherosclerotic progression increased from top to bottom in CLUE, typified by the frequent detection of early disease in the carotid bulb, then occasional cardiac manifestations, followed by the infrequent late manifestation of an abdominal aortic aneurysm. In our practice, performance of the complete CLUE starting at the top (carotids), changing transducers to work backward in the thorax (cardiac, lung, and inferior vena cava), and finishing with the bottom (aorta) was often dependent upon equipment and linear probe availability at the point‐of‐care.

A formalized CLUE curriculum was implemented into the residency in 2006. Twelve monthly 1‐hour CLUE lectures were given per year. Most lectures were 3045 minutes in length, leaving 1530 minutes for imaging resident or patient volunteers. All forms of ultrasound devices available to the residents, including pocket‐sized, hand‐carried, cart‐based, and standard ultrasound machines, were used in this forum. To learn the fundamentals of imaging technique, the intern during the cardiology consultation month rotation was first expected to image 1030 patients in the echocardiography and vascular ultrasound labs under the tutelage of the sonographers. Once weekly, 1‐hour bedside teaching was given to junior and senior residents on the intensive care unit (ICU) and cardiology consult rotations, in a traditional case‐based format. Over the ICU month rotation, junior and senior residents could each image an additional 1030 patients, resulting in a minimum of 30 studies obtained on acutely ill patients during the ICU rotations of residency. During clinical care rotations over the 3‐year residency, all residents imaged a minimum of 30 patients (at least 10 proctored studies during their internship cardiology consultation month, 10 proctored during ICU junior year rotations, and 10 proctored during ICU senior year rotations), with some residents imaging over a hundred patients (Table 2). To assist their education in CLUE, multiple learning aides were made available, including instructional how‐to‐image videos, a 200‐page syllabus, self‐assessment tests, and an instructional web site. Overall, the independent study and performance of CLUE was encouraged, but without formal performance incentives, monitoring, or effect upon residency evaluations.

Summary of Resident Curriculum and Estimates of Hours Spent
 LectureImagingOther
  • NOTE: CLUE curriculum (lectures and bedside teaching, imaging opportunities, and extracurricular) as noted by postgraduate year as provided. Estimated hours typically observed by faculty summarized at bottom and account for excused absences due to mandatory resident hour limitations, vacations, and away rotations. Abbreviations: CHF, congestive heart failure; CLUE‐CEX, cardiovascular limited ultrasound exam‐clinical exercise; ED, emergency department; ICU, intensive care unit; PGY, postgraduate year.

PGY‐1 (intern)12 (1‐hr) conferences; Web site instruction; syllabus; 12 (1‐hr) bedside ICU roundsEcho lab imaging with 20 (10 proctored) studies on cardiology consults; outpatient cardiology clinicsResearch; imaging in ICU, CHF, and medical clinics; ED
PGY‐2 (junior)12 (1‐hr) conferences; Web site instruction; syllabus; 8 (1‐hr) bedside ICU rounds20 (10 proctored) during 2 ICU rotationsResearch; teaching others; imaging in CHF and medical clinics; ED; echo lab
PGY‐3 (senior)12 (1‐hr) conferences; Web site instruction; syllabus; 12 (1‐hr) bedside ICU rounds20 (10 proctored) during 2 ICU rotations, cardiology consults, echo labResearch; teaching others; imaging in CHF and medical clinics; ED; CLUE‐CEX
Time completed (estimate)50 hr60 cases (30 proctored) 

At our institution, the medical director of the Echocardiography and Vascular ultrasound laboratory was a cardiologist (B.J.K.) who directed the CLUE training program. The Director provided the monthly lecture series to the entire residency and was responsible for weekly 1‐hour bedside ICU rounds. If given maintenance responsibilities of weekly bedside ICU rounds (1 hour/week), monthly lecture and preparation (5 hours/month), and availability to teach the cardiology intern (3 hours/month) and maintain the Web site (4 hours/month), the program required 4 hours/week of the Director's time. The program used 3 dedicated devices: the SonoSite 180 (SonoSite, Inc, Bothell, WA), the MicroMaxx (SonoSite, Inc) and, in 2010, a pocket‐sized cardiac ultrasound stethoscope, the Vscan (GE Healthcare, Wauwatosa, WI). No patient charges were submitted for performance or interpretation of any CLUE.

Assessment and Follow‐Up

A proficiency test was performed at the end of each resident's senior year. The test, cardiovascular limited ultrasound exam‐clinical exercise (CLUE‐CEX), involved imaging any available, consenting patient and assessing the resident's technical skills by image quality, knowledge of diagnostic criteria, and ability to discuss the clinical aspects of potential findings in a question‐and‐answer oral interview format, typically requiring 2030 minutes to perform. Each resident CLUE view was rated for: (1) image quality which accounted for 44% of total exam points, (2) specific knowledge related to each view which accounted for 28% of total exam points, and (3) diagnostic accuracy of the interpretation of each view which accounted for 28% of total exam points (see Figure 1). CLUE‐CEX scores were recorded as a percentage of total possible points, normalized to the difficulty of imaging the individual patient as determined by the Director's imaging. The test encompassed performance of all 7 views, demonstrated in 2 exams employing 2 transducers (cardiac and vascular) on the same patient (Figure 1). A passing threshold had been empirically derived at >80% of the total available points, a value that: (1) required performance in all 3 categories, (2) subjectively correlated to competency when assessed by the Director, and (3) had parity with other thresholds of clinical skill assessment by faculty and in graduate education. The Director had no knowledge of non‐CLUE resident evaluations, In‐training scores, or academic performance outside of CLUE. Residents were not remanded for CLUE‐CEX failure.

Figure 1
Cardiovascular limited ultrasound exam‐clinical exercise (CLUE‐CEX) form.

The graduating class of 2011 was the first class to initially enter into an entire residency program fully immersed in the CLUE curriculum, and was therefore specifically asked to report their impression of the CLUE program after graduation through a post‐residency questionnaire. A Likert‐type scale (1 = strongly disagree, 2 = disagree, 3 = neutral, 4 = agree, 5 = strongly agree) was used to assess the perceived validity of the following statements: (1) CLUE improved my own bedside cardiovascular evaluation; and (2) I would use CLUE if ultrasound were available in my future position. Each resident was then asked if too much, not enough, or an appropriate amount of time was spent to learn CLUE, and to choose the most effective form of CLUE teaching to which they were exposed: didactic lectures, bedside ICU teaching, Web site/syllabus, and one‐to‐one training with the Director or sonographer.

Statistical Analysis

The CLUE experience was divided into 3 phases: (1) pre‐CLUE era, the 4‐year period (classes graduating 20022005) prior to the institution of the formal CLUE curriculum; (2) the 2‐year CLUE phase‐in period (classes graduating 20062007), in which portions of the residency were undergoing the 3‐year curriculum; (3) the 4‐year CLUE‐CEX era (classes graduating 20082011) when all residency classes were trained in the standardized fashion and underwent CLUE‐CEX assessment. In‐training postgraduate year‐3 (PGY‐3) scores, the result of a nationwide standardized test developed by the American College of Physicians, were used as representative of senior resident academic knowledge. A percentile rank score is provided to compare residents to nationwide data. The group of residents who had been selected to be the following year's chief residents had their CLUE‐CEX scores analyzed as a subgroup.

Data are presented as mean standard deviation and analyzed in SPSS, version 12.0 (SPSS, Inc, Chicago, IL). Linear regression was used to investigate the relationship between In‐training percentile ranks and CLUE‐CEX scores. Analysis of variance was used to determine any effect of gender and chief resident selection on CLUE‐CEX, and to assess average resident In‐training percentile ranks during the pre‐CLUE and CLUE‐CEX periods. Subset analysis of individual CLUE‐CEX scores was performed in regards to image quality, diagnostic knowledge, and interpretative skills. A value of P < 0.05 was considered significant.

RESULTS

Observations During CLUE Program Development

CLUE‐CEX scores (20082011) included data from 41 residents; 51% were male. In the class of 2009, one second‐year male resident transferred to another program for nonacademic reasons, reducing its number to 9. We observed that the impact of the CLUE program depended in part upon resident‐to‐resident teaching and required a critical mass of residents to be trained during a phase‐in period before a maximal effect could be appreciated. We observed that didactic knowledge occurred before imaging skills and remained dominant by graduation, with mean percentile CLUE‐CEX scores for image quality, knowledge, and interpretative accuracy at 82% 5%, 91% 3%, and 91% 8%, respectively. Residents typically found apical lung imaging the easiest to perform (CLUE‐CEX score of 89% 19%), followed by carotid (84% 18%), inferior vena cava (IVC) imaging (84% 26%), screening for abdominal aortic aneurysm (AAA) (83% 2 4%), parasternal long‐axis (79% 30%), and subcostal cardiac 4‐chamber imaging (73% 33%). Each view had technical and diagnostic pitfalls that were noted during resident practice (see Table 1), resulting in changes in our teaching and case review in subsequent years.

Residency and CLUE Performance

In attempting to achieve a CLUE proficiency score of >80% on the CLUE‐CEX in their graduating year, 8/41 (19.5%) senior residents failed. In these 8 residents, imaging quality, knowledge, and interpretative accuracy were all depressed: 55% 19%, 79% 11%, and 75% 11%, respectively. Two of these 8 had been selected as future chief residents over the 4‐year period, positions typically awarded to 2 residents per graduating year. The performance of the residents is seen in Table 3. The CLUE program did not exert a negative effect upon the academic performance of the residency, as evidenced by the lack of a significant difference in the Pre‐CLUE, 2‐year CLUE, and CLUE‐CEX periods in regards to average resident In‐training percentile rank scores (67.5 20.1, 62.3 20.5, 69.4 16.9, respectively; P = 0.37).

Resident Performance
Time Era (Year of Graduation)nFail RateCLUE‐CEX (Mean SD)Resident IT Percentile Rank (Mean SD) (Range)
  • NOTE: Table shows mean standard deviation of CLUE‐CEX scores and resident In‐training percentile rank which represents the average of the residents' national percentile ranks of their In‐training PGY‐3 total scores during the corresponding time (Pre‐CLUE 4 years, CLUE phase‐in 2 years, CLUE‐CEX 4 years). Fail rate represents the % of residents who did not pass the CLUE‐CEX (80% correct criterion). Yearly data is listed for each of the CLUE‐CEX years, 20082011. Year denotes the year of graduation. Abbreviations: CLUE‐CEX, cardiovascular limited ultrasound exam‐clinical exercise; IT, In‐training; PGY, postgraduate year; SD, standard deviation.

Pre‐CLUE (20022005)39  67.5 20.1 (2099)
Phase‐in CLUE (20062007)19  62.3 20.5 (2097)
CLUE‐CEX (20082011)4119%87.4 11.969.4 16.9 (3499)
Year 20081136%84.3 13.974.7 17.9 (4599)
Year 2009911%89.1 7.073.0 16.6 (3493)
Year 20101030%84.2 16.957.1 12.7 (4287)
Year 2011110%92.1 5.772.4 15.9 (3499)

Figure 2 shows the relationship between CLUE‐CEX scores and In‐training PGY‐3 scores. There was no significant relationship between resident academic performance and CLUE capabilities (r = 0.05, P = 0.75). Similarly, chief resident performance (n = 14) was not significantly associated with CLUE‐CEX scores (r = 0.15, P = 0.37), nor was male gender (P = 0.07). Approximately one‐half (49%) of the residents in the 4‐year CLUE‐CEX era entered fellowships, unchanged from historic rates, with only 1 resident during this era entering into a cardiology fellowship.

Figure 2
Relationship between CLUE and academic performance. graph of CLUE‐CEX versus In‐training PGY‐3 percentile ranks. Trendline is shown (r = 0.051, P = 0.75) and demonstrates no significant correlation. Abbreviations: CLUE‐CEX, cardiovascular limited ultrasound exam‐clinical exercise; PGY‐3, postgraduate year‐3.

The Likert‐type questionnaire was returned by 11/11 graduating residents in 2011. Mean score of 4.3 0.6 (range: 35), with 6/11 responding agree, was given for the statement of whether CLUE improved the resident's own bedside exam. A score of 4.5 0.7 (range: 35), with 7/11 responding strongly agree, was given for whether the resident would use CLUE in the future if ultrasound were available. The majority (9/11) of residents felt that the time spent on CLUE was appropriate, with 2 residents responding not enough. Residents ranked one‐to‐one training with the Director(n = 6), followed by bedside ICU rounds (n = 5) as the preferred teaching methods to learn CLUE.

DISCUSSION

We report the experience of enrolling 6 consecutive classes, in an internal medicine residency, to test the feasibility of incorporating ongoing training in a specific, evidence‐based cardiovascular limited ultrasound examination within an already existing 3‐year curriculum. Using unbiased and complete enrollment, we found that residents who perform well on standardized academic testing or who are selected as chief residents do not necessarily perform more competently in CLUE, and that a significant overall initial resident failure rate can be anticipated. By questionnaire, residents felt confident in using the technique to improve their future bedside exams.

Burgeoning interest in the limited or focused application of ultrasound during bedside evaluation has already resulted in the incorporation of ultrasound training into emergency medicine residencies and critical care fellowships, with minimal standardization on curriculum, teaching methodology, or competency requirements. Given the multiple subspecialty applications for ultrasound, the potential exists of excessive diversity in bedside ultrasound practice, weakening the development of a single, simplified exam technique as a clinical tool for all physicians.31 Prior feasibility studies914 have evaluated the learning curve of internal medicine or primary care residents in performing various limited exams, but have not provided the rationale regarding the imaging protocols, the methods used for teaching, and the assessment of the program results over a sustained period of time. Furthermore, prior studies have not randomized subject trainees, likely resulting in the selected enrollment of highly motivated or skilled residents who want to perform a particular technique or have a bias to learn it. Our reported 19% unremanded failure rate on CLUE‐CEX will likely be more reflective of the general experience when initially integrating entire classes of internal medicine residents into a standard curriculum. The feasibility of introducing ultrasound at an earlier stage than residency may improve familiarity with the modality, and a 4‐year medical‐student curriculum has been recently described.32 Although introduction in medical school could allow for more adept and specific clinical training during residency, the optimal time for education in bedside ultrasound remains unclear.

Critical to the development of our program was the necessity to commit to teaching a single exam, the CLUE. We derived CLUE to quickly screen for important targets that had evidence‐basis to affect outcome, such as manifestations of subclinical atherosclerosis or chamber enlargement due to elevated filling pressures. Subsequent CLUE outcome studies have demonstrated diagnostic accuracy and prognostic value in its components,18, 26, 29, 30 and an effect upon medical decision‐making,21 even when performed by briefly trained novices.18, 21, 30 It is anticipated that this cardiovascular examination will later expand to a more advanced version or become a component of a full‐body ultrasound‐assisted physical. Therefore, evidence‐basis and brevity governed the development of a practical and teachable fundamental CLUE, and our skill assessment results are likely specific to CLUE itself.

This report contains primarily observations noted during the development of our program, written in retrospect with emphasis on real world feasibility. It was not a rigorous evaluation of specific ultrasound teaching methods. We found that training is feasible, at modest costs, when existing in‐hospital resources are utilized and include a part‐time faculty appointment and shared devices. Training the sonographers to perform CLUE as a part of the standard echocardiogram was a trivial task, but created the great benefit of being able to retrospectively review both the CLUE and formal echo in case review and teaching. Monthly CLUE lectures in the daily noon conference docket, and the use of the cardiology consultation and ICU rotations, allowed integration of the CLUE curriculum into preexisting venues and persistent practice opportunities within the residency. To prevent bias, we intentionally did not track, bring attention to, or incentivize resident performance in CLUE over any other topic; therefore, we can only approximate lecture and bedside teaching hours spent by each resident in light of detractions due to residency hour restrictions, vacations, and away rotations (Table 2). The CLUE‐CEX, although subject to the biases of any subjective resident skill assessment, was easily accomplished using a single form and faculty member, and was an efficient tool for program feedback and development.

In conclusion, we report the feasibility of sustained incorporation of an ultrasound training program in an internal medicine residency. We await studies regarding clinical outcome and validation of similar experiences in larger, multicenter programs.

Acknowledgements

The authors acknowledge the sonographers of the Scripps Mercy Cardiovascular Ultrasound Laboratory and Dudie Keane, for their dedication and assistance in the implementation of the CLUE program.

Disclosure: Nothing to report.

Note: The correction that was made, was the text in Fig. 1 and Fig. 2 were reversed. This article was published online on May 17, 2012. An error was subsequently identified. This notice is included in the online and print versions to indicate that both have been corrected on May 22, 2012.

References
  1. Kimura BJ,Gilcrease GW,Showalter BK,Phan JN,Wolfson T.Diagnostic performance of a pocket‐sized ultrasound device for quick‐look cardiac imaging.Am J Emerg Med. 2012;30(1):32–36.
  2. Frederiksen CA,Juhl‐Olsen P,Larsen UT,Nielsen DG,Eika B,Sloth E.New pocket echocardiography device is interchangeable with high‐end portable system when performed by experienced examiners.Acta Anaesthesiol Scand.2010;54(10):12171223.
  3. Cardim N,Fernandez Golfin C,Ferreira D, et al.Usefulness of a new miniaturized echocardiographic system in outpatient cardiology consultations as an extension of physical examination.J Am Soc Echocardiogr.2011;24(2):117124.
  4. Prinz C,Voigt JU.Diagnostic accuracy of a hand‐held ultrasound scanner in routine patients referred for echocardiography.J Am Soc Echocardiogr.2011;24(2):111116.
  5. Liebo MJ,Israel RL,Lillie EO,Smith MR,Rubenson DS,Topol EJ.is pocket mobile echocardiography the next‐generation stethoscope? A cross‐sectional comparison of rapidly acquired images with standard transthoracic echocardiography.Ann Intern Med.2011;155(1):3338.
  6. Kimura BJ,DeMaria AN.Hand‐carried ultrasound: evolution, not revolution.Nat Clin Pract Cardiovasc Med.2005;2:217223.
  7. Popp RL.The physical examination of the future: echocardiography as part of the assessment.ACC Curr Rev.1998;7:7981.
  8. Roelandt JRTC.A personal ultrasound imager (ultrasound stethoscope): a revolution in the physical cardiac diagnosis!Eur Heart J.2002;23:523527.
  9. Alexander JH,Peterson ED,Chen AY,Harding TM,Adams DB,Kisslo JA.Feasibility of point‐of‐care echocardiography by internal medicine house staff.Am Heart J.2004;147:476481.
  10. DeCara JM,Lang RM,Koch R,Bala R,Penzotti J,Spencer KT.The use of small personal ultrasound devices by internists without formal training in echocardiography.Eur J Echocardiogr.2003;4:141147.
  11. Bailey FP,Autl M,Greengold NL,Rosendahl T,Cossman D.Ultrasonography performed by primary care residents for abdominal aortic ultrasound screening.J Gen Intern Med.2001;16:845849.
  12. Hellman DB,Whiting‐O'Keefe Q,Shapiro EP,Martin LD,Martire C,Ziegelstein RC.The rate at which residents learn to use hand‐held echocardiography at the bedside.Am J Med.2005;118:10101018.
  13. Kobal SL,Atar S,Siegel RJ.Hand‐carried ultrasound improves the bedside cardiovascular examination.Chest.2004;126:693701.
  14. Brennan JM,Blair JE,Goonewardena S, et al.A comparison by medicine residents of physical examination versus hand‐carried ultrasound for estimation of right atrial pressure.Am J Cardiol.2007;99(11):16141616.
  15. Kimura BJ,Pezeshki B,Frack SA,DeMaria AN.Feasibility of “limited” echo imaging: characterization of incidental findings.J Am Soc Echocardiogr.1998;11:746750.
  16. Kimura BJ,Scott R,Willis CL,DeMaria AN.Diagnostic accuracy and cost‐effective implications of an ultrasound screening strategy in suspected mitral valve prolapse.Am J Med.2000;108:331333.
  17. Kimura BJ,DeMaria AN.Indications for limited echo imaging: a mathematical model.J Am Soc Echocardiogr.2000;13:855861.
  18. Kimura BJ,Bocchicchio M,Willis CL,DeMaria AN.Screening cardiac ultrasound examination in patients with suspected cardiac disease in the emergency room setting.Am Heart J.2001;142:324330.
  19. Kimura BJ,Willis CL,Blanchard DG,DeMaria AN.Limited cardiac ultrasound examination for cost‐effective echo referral.J Am Soc Echocardiogr.2002;15:640646.
  20. Kimura BJ,DeMaria AN.Time requirements of the standard echocardiogram: implications regarding “limited” studies.J Am Soc Echocardiogr.2003;16:10151018.
  21. Kimura BJ,Shaw DJ,Agan DL,Amundson SA,Ping AC,DeMaria AN.Value of a cardiovascular limited ultrasound examination using a hand‐carried ultrasound device on clinical management in an outpatient medical clinic.Am J Cardiol.2007;100:321325.
  22. Kimura BJ,Fowler SJ,Nguyen DT,Amundson SA,DeMaria AN.Briefly‐trained physicians can screen for early atherosclerosis at the bedside using hand‐held ultrasound.Am J Cardiol.2003;92:239240.
  23. Kimura BJ,Amundson SA,Willis CL,Gilpin EA,DeMaria AN.Usefulness of a hand‐held ultrasound device for the bedside examination of left ventricular function.Am J Cardiol2002;90(9):10381039.
  24. Kimura BJ,Fowler SJ,Fergus TS, et al.Detection of left atrial enlargement using hand‐carried ultrasound devices: implications for bedside examination.Am J Med.2005;118(8):912916.
  25. Kimura BJ,Kedar E,Weiss DE,Wahlstrom CL,Agan DL.A hand‐carried ultrasound sign of cardiac disease: the left atrium‐to‐aorta diastolic ratio.Am J Emerg Med.2010;28(2):203207.
  26. Kimura BJ,Yogo N,O'Connell C,Phan JN,Showalter BK,Wolfson T.A cardiopulmonary limited ultrasound examination for “quick‐look” bedside application.Am J Cardiol.2011;108:586590.
  27. Scalea TM,Rodriguez A,Chiu WC, et al.Focused Assessment with Sonography for Trauma (FAST): results from an international consensus conference.J Trauma.1999;46:466472.
  28. Kataoka H,Takada S.The role of thoracic ultrasonography for evaluation of patients with decompensated chronic heart failure.J Am Coll Cardiol.2000;35:16381646.
  29. Fremont B,Pacouret G,Jacobi D,Puglisi R,Charbonnier B,De Labriolle A.Prognostic value of echocardiographic right/left ventricular end‐diastolic diameter ration in patients with acute pulmonary embolism.Chest.2008;133:358362.
  30. Goonewardena SN,Gemignani A,Ronan A, et al.Comparison of hand‐carried ultrasound assessment of the inferior vena cava and N‐terminal pro‐brain natriuretic peptide for predicting readmission after hospitalization for acute decompensated heart failure.J Am Coll Cardiol Img.2008;1:595601.
  31. Kimura BJ,Amundson SA,Shaw DJ.Hospitalist use of hand‐carried ultrasound: preparing for battle.J Hosp Med.2010;5:163167.
  32. Hoppmann RA,Rao VV,Poston MB, et al.An integrated ultrasound curriculum (iUSC) for medical students: 4‐year experience.Crit Ultrasound J.2011;3(1):112.
References
  1. Kimura BJ,Gilcrease GW,Showalter BK,Phan JN,Wolfson T.Diagnostic performance of a pocket‐sized ultrasound device for quick‐look cardiac imaging.Am J Emerg Med. 2012;30(1):32–36.
  2. Frederiksen CA,Juhl‐Olsen P,Larsen UT,Nielsen DG,Eika B,Sloth E.New pocket echocardiography device is interchangeable with high‐end portable system when performed by experienced examiners.Acta Anaesthesiol Scand.2010;54(10):12171223.
  3. Cardim N,Fernandez Golfin C,Ferreira D, et al.Usefulness of a new miniaturized echocardiographic system in outpatient cardiology consultations as an extension of physical examination.J Am Soc Echocardiogr.2011;24(2):117124.
  4. Prinz C,Voigt JU.Diagnostic accuracy of a hand‐held ultrasound scanner in routine patients referred for echocardiography.J Am Soc Echocardiogr.2011;24(2):111116.
  5. Liebo MJ,Israel RL,Lillie EO,Smith MR,Rubenson DS,Topol EJ.is pocket mobile echocardiography the next‐generation stethoscope? A cross‐sectional comparison of rapidly acquired images with standard transthoracic echocardiography.Ann Intern Med.2011;155(1):3338.
  6. Kimura BJ,DeMaria AN.Hand‐carried ultrasound: evolution, not revolution.Nat Clin Pract Cardiovasc Med.2005;2:217223.
  7. Popp RL.The physical examination of the future: echocardiography as part of the assessment.ACC Curr Rev.1998;7:7981.
  8. Roelandt JRTC.A personal ultrasound imager (ultrasound stethoscope): a revolution in the physical cardiac diagnosis!Eur Heart J.2002;23:523527.
  9. Alexander JH,Peterson ED,Chen AY,Harding TM,Adams DB,Kisslo JA.Feasibility of point‐of‐care echocardiography by internal medicine house staff.Am Heart J.2004;147:476481.
  10. DeCara JM,Lang RM,Koch R,Bala R,Penzotti J,Spencer KT.The use of small personal ultrasound devices by internists without formal training in echocardiography.Eur J Echocardiogr.2003;4:141147.
  11. Bailey FP,Autl M,Greengold NL,Rosendahl T,Cossman D.Ultrasonography performed by primary care residents for abdominal aortic ultrasound screening.J Gen Intern Med.2001;16:845849.
  12. Hellman DB,Whiting‐O'Keefe Q,Shapiro EP,Martin LD,Martire C,Ziegelstein RC.The rate at which residents learn to use hand‐held echocardiography at the bedside.Am J Med.2005;118:10101018.
  13. Kobal SL,Atar S,Siegel RJ.Hand‐carried ultrasound improves the bedside cardiovascular examination.Chest.2004;126:693701.
  14. Brennan JM,Blair JE,Goonewardena S, et al.A comparison by medicine residents of physical examination versus hand‐carried ultrasound for estimation of right atrial pressure.Am J Cardiol.2007;99(11):16141616.
  15. Kimura BJ,Pezeshki B,Frack SA,DeMaria AN.Feasibility of “limited” echo imaging: characterization of incidental findings.J Am Soc Echocardiogr.1998;11:746750.
  16. Kimura BJ,Scott R,Willis CL,DeMaria AN.Diagnostic accuracy and cost‐effective implications of an ultrasound screening strategy in suspected mitral valve prolapse.Am J Med.2000;108:331333.
  17. Kimura BJ,DeMaria AN.Indications for limited echo imaging: a mathematical model.J Am Soc Echocardiogr.2000;13:855861.
  18. Kimura BJ,Bocchicchio M,Willis CL,DeMaria AN.Screening cardiac ultrasound examination in patients with suspected cardiac disease in the emergency room setting.Am Heart J.2001;142:324330.
  19. Kimura BJ,Willis CL,Blanchard DG,DeMaria AN.Limited cardiac ultrasound examination for cost‐effective echo referral.J Am Soc Echocardiogr.2002;15:640646.
  20. Kimura BJ,DeMaria AN.Time requirements of the standard echocardiogram: implications regarding “limited” studies.J Am Soc Echocardiogr.2003;16:10151018.
  21. Kimura BJ,Shaw DJ,Agan DL,Amundson SA,Ping AC,DeMaria AN.Value of a cardiovascular limited ultrasound examination using a hand‐carried ultrasound device on clinical management in an outpatient medical clinic.Am J Cardiol.2007;100:321325.
  22. Kimura BJ,Fowler SJ,Nguyen DT,Amundson SA,DeMaria AN.Briefly‐trained physicians can screen for early atherosclerosis at the bedside using hand‐held ultrasound.Am J Cardiol.2003;92:239240.
  23. Kimura BJ,Amundson SA,Willis CL,Gilpin EA,DeMaria AN.Usefulness of a hand‐held ultrasound device for the bedside examination of left ventricular function.Am J Cardiol2002;90(9):10381039.
  24. Kimura BJ,Fowler SJ,Fergus TS, et al.Detection of left atrial enlargement using hand‐carried ultrasound devices: implications for bedside examination.Am J Med.2005;118(8):912916.
  25. Kimura BJ,Kedar E,Weiss DE,Wahlstrom CL,Agan DL.A hand‐carried ultrasound sign of cardiac disease: the left atrium‐to‐aorta diastolic ratio.Am J Emerg Med.2010;28(2):203207.
  26. Kimura BJ,Yogo N,O'Connell C,Phan JN,Showalter BK,Wolfson T.A cardiopulmonary limited ultrasound examination for “quick‐look” bedside application.Am J Cardiol.2011;108:586590.
  27. Scalea TM,Rodriguez A,Chiu WC, et al.Focused Assessment with Sonography for Trauma (FAST): results from an international consensus conference.J Trauma.1999;46:466472.
  28. Kataoka H,Takada S.The role of thoracic ultrasonography for evaluation of patients with decompensated chronic heart failure.J Am Coll Cardiol.2000;35:16381646.
  29. Fremont B,Pacouret G,Jacobi D,Puglisi R,Charbonnier B,De Labriolle A.Prognostic value of echocardiographic right/left ventricular end‐diastolic diameter ration in patients with acute pulmonary embolism.Chest.2008;133:358362.
  30. Goonewardena SN,Gemignani A,Ronan A, et al.Comparison of hand‐carried ultrasound assessment of the inferior vena cava and N‐terminal pro‐brain natriuretic peptide for predicting readmission after hospitalization for acute decompensated heart failure.J Am Coll Cardiol Img.2008;1:595601.
  31. Kimura BJ,Amundson SA,Shaw DJ.Hospitalist use of hand‐carried ultrasound: preparing for battle.J Hosp Med.2010;5:163167.
  32. Hoppmann RA,Rao VV,Poston MB, et al.An integrated ultrasound curriculum (iUSC) for medical students: 4‐year experience.Crit Ultrasound J.2011;3(1):112.
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Observations during development of an internal medicine residency training program in cardiovascular limited ultrasound examination
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SHM Leaders Discuss Growth of Specialty Hospitalist Medicine

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SHM Leaders Discuss Growth of Specialty Hospitalist Medicine

The growth of specialty hospitalist medicine is an opportunity to improve patient outcomes, but the evolution of care delivery must be closely watched, according to one of the authors of an editorial in the Journal of the American Medical Association.

"It's a mistake to dig your heels in and insist on preserving traditional practice models when they may no longer fit," says John Nelson, MD, MHM, FACP, medical director of the hospitalist practice at Overlake Hospital Medical Center, Bellevue, Wash. "It's just as big a mistake to blindly hop on the hospitalist bandwagon without thinking deliberately about its costs and benefits and how to make it the best it can be."

Dr. Nelson, an SHM co-founder and practice management columnist for The Hospitalist, penned the editorial, "Specialty Hospitalists: Analyzing an Emerging Phenomenon,” with SHM CEO Larry Wellikson, MD, SFHM, and HM pioneer Robert Wachter, MD, MHM. The two-page article suggests that the growth of the hospitalist model to include such specialties as neurology, dermatology, obstetrics, surgery, and psychiatry is a natural extension of how the hospitalist model blossomed in the early 1990s.

"Doctors are headed elsewhere, away from the hospital," Dr. Nelson says. "The solution is, in many cases, if we can't get a lot of these doctors to do hospital work some of the time, can we get a few doctors to do hospital work all of the time?"

The article, which echoes a 2011 blog post by Dr. Wachter, proposes four guiding questions on whether the use of the hospitalist model is appropriate for a given specialty. Those answers are being answered by the marketplace which, in turn, is propelling the trend of specialty HM doctors.

"So many things that happen in medicine are engineered and tracked by some entity," Dr. Nelson says. "Not in this case—and that is huge."

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The growth of specialty hospitalist medicine is an opportunity to improve patient outcomes, but the evolution of care delivery must be closely watched, according to one of the authors of an editorial in the Journal of the American Medical Association.

"It's a mistake to dig your heels in and insist on preserving traditional practice models when they may no longer fit," says John Nelson, MD, MHM, FACP, medical director of the hospitalist practice at Overlake Hospital Medical Center, Bellevue, Wash. "It's just as big a mistake to blindly hop on the hospitalist bandwagon without thinking deliberately about its costs and benefits and how to make it the best it can be."

Dr. Nelson, an SHM co-founder and practice management columnist for The Hospitalist, penned the editorial, "Specialty Hospitalists: Analyzing an Emerging Phenomenon,” with SHM CEO Larry Wellikson, MD, SFHM, and HM pioneer Robert Wachter, MD, MHM. The two-page article suggests that the growth of the hospitalist model to include such specialties as neurology, dermatology, obstetrics, surgery, and psychiatry is a natural extension of how the hospitalist model blossomed in the early 1990s.

"Doctors are headed elsewhere, away from the hospital," Dr. Nelson says. "The solution is, in many cases, if we can't get a lot of these doctors to do hospital work some of the time, can we get a few doctors to do hospital work all of the time?"

The article, which echoes a 2011 blog post by Dr. Wachter, proposes four guiding questions on whether the use of the hospitalist model is appropriate for a given specialty. Those answers are being answered by the marketplace which, in turn, is propelling the trend of specialty HM doctors.

"So many things that happen in medicine are engineered and tracked by some entity," Dr. Nelson says. "Not in this case—and that is huge."

The growth of specialty hospitalist medicine is an opportunity to improve patient outcomes, but the evolution of care delivery must be closely watched, according to one of the authors of an editorial in the Journal of the American Medical Association.

"It's a mistake to dig your heels in and insist on preserving traditional practice models when they may no longer fit," says John Nelson, MD, MHM, FACP, medical director of the hospitalist practice at Overlake Hospital Medical Center, Bellevue, Wash. "It's just as big a mistake to blindly hop on the hospitalist bandwagon without thinking deliberately about its costs and benefits and how to make it the best it can be."

Dr. Nelson, an SHM co-founder and practice management columnist for The Hospitalist, penned the editorial, "Specialty Hospitalists: Analyzing an Emerging Phenomenon,” with SHM CEO Larry Wellikson, MD, SFHM, and HM pioneer Robert Wachter, MD, MHM. The two-page article suggests that the growth of the hospitalist model to include such specialties as neurology, dermatology, obstetrics, surgery, and psychiatry is a natural extension of how the hospitalist model blossomed in the early 1990s.

"Doctors are headed elsewhere, away from the hospital," Dr. Nelson says. "The solution is, in many cases, if we can't get a lot of these doctors to do hospital work some of the time, can we get a few doctors to do hospital work all of the time?"

The article, which echoes a 2011 blog post by Dr. Wachter, proposes four guiding questions on whether the use of the hospitalist model is appropriate for a given specialty. Those answers are being answered by the marketplace which, in turn, is propelling the trend of specialty HM doctors.

"So many things that happen in medicine are engineered and tracked by some entity," Dr. Nelson says. "Not in this case—and that is huge."

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SHM Leaders Discuss Growth of Specialty Hospitalist Medicine
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Society of Hospital Medicine Joins Campaign against Unnecessary Medical Treatments

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Society of Hospital Medicine Joins Campaign against Unnecessary Medical Treatments

SHM has joined the American Board of Internal Medicine (ABIM) Foundation's Choosing Wisely campaign, through which medical societies identify tests and procedures that are common in their specialties but often unnecessary.

The campaign, launched in April, currently includes nine societies that have each crafted lists of "five things physicians and patients should question." SHM's Healthcare Quality and Patient Safety Committee is now working on its own evidence-based list, with a focus on the inpatient setting. The list should be released this fall, says Gregory Maynard, MD, MSc, SFHM, senior vice president of SHM’s Center for Healthcare Improvement and Innovation.

"We will also be looking for innovative methods to reinforce these messages and integrate them into daily practice," Dr. Maynard says. Unless physicians squeeze out healthcare's waste and inefficiency in ways that actually improve care, he says, "healthcare spending could be cut in potentially destructive ways."

University of California at San Francisco's Robert Wachter, MD, MHM, a co-founder of SHM who also is chair-elect of ABIM's board of directors, calls the campaign a significant advance for the quality movement, "which has not previously embraced cost and waste reduction as strongly as it needs to."

Dr. Wachter advises hospitalists take advantage of the currently available lists of questionable treatments in such areas as cardiology, radiology, and nephrology. "This is extraordinarily hopeful. The medical profession is finally stepping up to the plate," he says.

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The Hospitalist - 2012(05)
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SHM has joined the American Board of Internal Medicine (ABIM) Foundation's Choosing Wisely campaign, through which medical societies identify tests and procedures that are common in their specialties but often unnecessary.

The campaign, launched in April, currently includes nine societies that have each crafted lists of "five things physicians and patients should question." SHM's Healthcare Quality and Patient Safety Committee is now working on its own evidence-based list, with a focus on the inpatient setting. The list should be released this fall, says Gregory Maynard, MD, MSc, SFHM, senior vice president of SHM’s Center for Healthcare Improvement and Innovation.

"We will also be looking for innovative methods to reinforce these messages and integrate them into daily practice," Dr. Maynard says. Unless physicians squeeze out healthcare's waste and inefficiency in ways that actually improve care, he says, "healthcare spending could be cut in potentially destructive ways."

University of California at San Francisco's Robert Wachter, MD, MHM, a co-founder of SHM who also is chair-elect of ABIM's board of directors, calls the campaign a significant advance for the quality movement, "which has not previously embraced cost and waste reduction as strongly as it needs to."

Dr. Wachter advises hospitalists take advantage of the currently available lists of questionable treatments in such areas as cardiology, radiology, and nephrology. "This is extraordinarily hopeful. The medical profession is finally stepping up to the plate," he says.

SHM has joined the American Board of Internal Medicine (ABIM) Foundation's Choosing Wisely campaign, through which medical societies identify tests and procedures that are common in their specialties but often unnecessary.

The campaign, launched in April, currently includes nine societies that have each crafted lists of "five things physicians and patients should question." SHM's Healthcare Quality and Patient Safety Committee is now working on its own evidence-based list, with a focus on the inpatient setting. The list should be released this fall, says Gregory Maynard, MD, MSc, SFHM, senior vice president of SHM’s Center for Healthcare Improvement and Innovation.

"We will also be looking for innovative methods to reinforce these messages and integrate them into daily practice," Dr. Maynard says. Unless physicians squeeze out healthcare's waste and inefficiency in ways that actually improve care, he says, "healthcare spending could be cut in potentially destructive ways."

University of California at San Francisco's Robert Wachter, MD, MHM, a co-founder of SHM who also is chair-elect of ABIM's board of directors, calls the campaign a significant advance for the quality movement, "which has not previously embraced cost and waste reduction as strongly as it needs to."

Dr. Wachter advises hospitalists take advantage of the currently available lists of questionable treatments in such areas as cardiology, radiology, and nephrology. "This is extraordinarily hopeful. The medical profession is finally stepping up to the plate," he says.

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Abused Children Treated in ED at Risk of Return

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BOSTON – Children treated in the emergency department for abuse or neglect are at increased risk for further maltreatment, even after medical or social service intervention, a study has shown.

Among nearly 44,000 pediatric emergency department (ED) visits with at least one ICD-9 code for maltreatment, 3% of the children returned one or more times and were again identified as victims of maltreatment, reported Michael C. Monuteaux, Sc.D., of Harvard Medical School, Boston.

Dr. Michael C. Monuteaux

Children who were admitted to a patient floor or to an intensive care unit on their initial visit were twice as likely as those who were treated and released to be readmitted on subsequent ED visits. Children under 5 years of age were the most vulnerable, the authors found.

"Even when maltreatment is identified in the ED, children are at risk for further victimization resulting in future ED care," Dr. Monuteaux said at the annual meeting of the Pediatric Academic Societies.

Coinvestigator Dr. Daniel M. Lindberg, an emergency physician at Brigham and Women’s Hospital in Boston, said in an interview that the Child Protective Services workers have "a tremendously difficult" job made even more difficult by increasing caseloads and proposed reductions in funding.

"If that happens, [there will be] fewer investigators or case workers who can do the kind of checking in to make sure that safety plans are being followed or dangerous people are kept away from kids at risk. My hope is that any intervention to support Child Protective Services workers, and decrease caseloads, will help decrease rates of recurrent abuse," he said.

Dr. Monuteaux and Dr. Lindberg took a retrospective look at data from an administrative database on children under 18 treated in the emergency departments of 41 U.S. hospitals in 2005-2010.

They identified 43,824 ED visits by 42,354 children with one or more ICD-9 principal or secondary diagnoses of physical or sexual abuse, or other/unspecified maltreatment, and used medical record numbers to track patients over time.

In all, 1,286 maltreated children (3.0%) returned for another ED visit and received a second diagnosis of maltreatment. The median age of the children was 3 years (range, 1-8 years), 63% were girls, and 60% were white. The majority of the children (90%) had two ED visits, 8% had three visits, and 2% were seen in the ED four or more times.

One-fourth of the returning patients were seen again in the emergency department within 21 days, half within 150 days, and two-thirds within 1 year.

Abuse and neglect was the primary diagnosis in 38%, sexual abuse in 18%, physical abuse in 17%, and other maltreatment or injury in 27%.

Overall, 20% were admitted to the hospital at the initial visit, 3% were admitted to an ICU, and 6% underwent surgery for their injuries.

Of 253 children admitted at the initial visit, 42% were also admitted on their second visit. In comparison, of the 1,033 children not admitted at their first ED visit, 7% were admitted on the second visit. The odds ratio (OR) for being admitted a second time after a first admission was 2.1 (95% confidence interval [CI], 1.6-2.8).

Similarly, of 78 children with an initial ICU stay, 17% went back to the ICU at the second ED visit, compared with 2% of those who were not put in intensive care at their first ED visit (OR, 2.2; 95% CI, 1.4-3.6).

In a multivariate analysis controlled for demographic and clinical factors, the only significant predictor of repeat ED visits was age younger than 5 years (OR, 1.47; 95% CI, 1.22-1.78).

Dr. Monuteaux noted that the study might underestimate the actual number of repeat abuse cases because of its reliance on ICD-9 codes and because some of the children may have had ED visits for abuse or neglect before the start of the study. It is also possible that the code for physical abuse reflects long-term complications from prior abuse and not a new episode. Additionally, the data were drawn from academic pediatric hospitals and may not reflect the experience of community and general hospitals.

"Despite the dedicated work of ED and child protection workers, children diagnosed with maltreatment in the ED are at risk for additional victimization and subsequent emergency care for maltreatment, which leads us to suggest that improvements in the child protection apparatus should be considered," Dr. Monuteaux concluded.

The study was internally funded. The authors reported having no relevant financial relationships.

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BOSTON – Children treated in the emergency department for abuse or neglect are at increased risk for further maltreatment, even after medical or social service intervention, a study has shown.

Among nearly 44,000 pediatric emergency department (ED) visits with at least one ICD-9 code for maltreatment, 3% of the children returned one or more times and were again identified as victims of maltreatment, reported Michael C. Monuteaux, Sc.D., of Harvard Medical School, Boston.

Dr. Michael C. Monuteaux

Children who were admitted to a patient floor or to an intensive care unit on their initial visit were twice as likely as those who were treated and released to be readmitted on subsequent ED visits. Children under 5 years of age were the most vulnerable, the authors found.

"Even when maltreatment is identified in the ED, children are at risk for further victimization resulting in future ED care," Dr. Monuteaux said at the annual meeting of the Pediatric Academic Societies.

Coinvestigator Dr. Daniel M. Lindberg, an emergency physician at Brigham and Women’s Hospital in Boston, said in an interview that the Child Protective Services workers have "a tremendously difficult" job made even more difficult by increasing caseloads and proposed reductions in funding.

"If that happens, [there will be] fewer investigators or case workers who can do the kind of checking in to make sure that safety plans are being followed or dangerous people are kept away from kids at risk. My hope is that any intervention to support Child Protective Services workers, and decrease caseloads, will help decrease rates of recurrent abuse," he said.

Dr. Monuteaux and Dr. Lindberg took a retrospective look at data from an administrative database on children under 18 treated in the emergency departments of 41 U.S. hospitals in 2005-2010.

They identified 43,824 ED visits by 42,354 children with one or more ICD-9 principal or secondary diagnoses of physical or sexual abuse, or other/unspecified maltreatment, and used medical record numbers to track patients over time.

In all, 1,286 maltreated children (3.0%) returned for another ED visit and received a second diagnosis of maltreatment. The median age of the children was 3 years (range, 1-8 years), 63% were girls, and 60% were white. The majority of the children (90%) had two ED visits, 8% had three visits, and 2% were seen in the ED four or more times.

One-fourth of the returning patients were seen again in the emergency department within 21 days, half within 150 days, and two-thirds within 1 year.

Abuse and neglect was the primary diagnosis in 38%, sexual abuse in 18%, physical abuse in 17%, and other maltreatment or injury in 27%.

Overall, 20% were admitted to the hospital at the initial visit, 3% were admitted to an ICU, and 6% underwent surgery for their injuries.

Of 253 children admitted at the initial visit, 42% were also admitted on their second visit. In comparison, of the 1,033 children not admitted at their first ED visit, 7% were admitted on the second visit. The odds ratio (OR) for being admitted a second time after a first admission was 2.1 (95% confidence interval [CI], 1.6-2.8).

Similarly, of 78 children with an initial ICU stay, 17% went back to the ICU at the second ED visit, compared with 2% of those who were not put in intensive care at their first ED visit (OR, 2.2; 95% CI, 1.4-3.6).

In a multivariate analysis controlled for demographic and clinical factors, the only significant predictor of repeat ED visits was age younger than 5 years (OR, 1.47; 95% CI, 1.22-1.78).

Dr. Monuteaux noted that the study might underestimate the actual number of repeat abuse cases because of its reliance on ICD-9 codes and because some of the children may have had ED visits for abuse or neglect before the start of the study. It is also possible that the code for physical abuse reflects long-term complications from prior abuse and not a new episode. Additionally, the data were drawn from academic pediatric hospitals and may not reflect the experience of community and general hospitals.

"Despite the dedicated work of ED and child protection workers, children diagnosed with maltreatment in the ED are at risk for additional victimization and subsequent emergency care for maltreatment, which leads us to suggest that improvements in the child protection apparatus should be considered," Dr. Monuteaux concluded.

The study was internally funded. The authors reported having no relevant financial relationships.

BOSTON – Children treated in the emergency department for abuse or neglect are at increased risk for further maltreatment, even after medical or social service intervention, a study has shown.

Among nearly 44,000 pediatric emergency department (ED) visits with at least one ICD-9 code for maltreatment, 3% of the children returned one or more times and were again identified as victims of maltreatment, reported Michael C. Monuteaux, Sc.D., of Harvard Medical School, Boston.

Dr. Michael C. Monuteaux

Children who were admitted to a patient floor or to an intensive care unit on their initial visit were twice as likely as those who were treated and released to be readmitted on subsequent ED visits. Children under 5 years of age were the most vulnerable, the authors found.

"Even when maltreatment is identified in the ED, children are at risk for further victimization resulting in future ED care," Dr. Monuteaux said at the annual meeting of the Pediatric Academic Societies.

Coinvestigator Dr. Daniel M. Lindberg, an emergency physician at Brigham and Women’s Hospital in Boston, said in an interview that the Child Protective Services workers have "a tremendously difficult" job made even more difficult by increasing caseloads and proposed reductions in funding.

"If that happens, [there will be] fewer investigators or case workers who can do the kind of checking in to make sure that safety plans are being followed or dangerous people are kept away from kids at risk. My hope is that any intervention to support Child Protective Services workers, and decrease caseloads, will help decrease rates of recurrent abuse," he said.

Dr. Monuteaux and Dr. Lindberg took a retrospective look at data from an administrative database on children under 18 treated in the emergency departments of 41 U.S. hospitals in 2005-2010.

They identified 43,824 ED visits by 42,354 children with one or more ICD-9 principal or secondary diagnoses of physical or sexual abuse, or other/unspecified maltreatment, and used medical record numbers to track patients over time.

In all, 1,286 maltreated children (3.0%) returned for another ED visit and received a second diagnosis of maltreatment. The median age of the children was 3 years (range, 1-8 years), 63% were girls, and 60% were white. The majority of the children (90%) had two ED visits, 8% had three visits, and 2% were seen in the ED four or more times.

One-fourth of the returning patients were seen again in the emergency department within 21 days, half within 150 days, and two-thirds within 1 year.

Abuse and neglect was the primary diagnosis in 38%, sexual abuse in 18%, physical abuse in 17%, and other maltreatment or injury in 27%.

Overall, 20% were admitted to the hospital at the initial visit, 3% were admitted to an ICU, and 6% underwent surgery for their injuries.

Of 253 children admitted at the initial visit, 42% were also admitted on their second visit. In comparison, of the 1,033 children not admitted at their first ED visit, 7% were admitted on the second visit. The odds ratio (OR) for being admitted a second time after a first admission was 2.1 (95% confidence interval [CI], 1.6-2.8).

Similarly, of 78 children with an initial ICU stay, 17% went back to the ICU at the second ED visit, compared with 2% of those who were not put in intensive care at their first ED visit (OR, 2.2; 95% CI, 1.4-3.6).

In a multivariate analysis controlled for demographic and clinical factors, the only significant predictor of repeat ED visits was age younger than 5 years (OR, 1.47; 95% CI, 1.22-1.78).

Dr. Monuteaux noted that the study might underestimate the actual number of repeat abuse cases because of its reliance on ICD-9 codes and because some of the children may have had ED visits for abuse or neglect before the start of the study. It is also possible that the code for physical abuse reflects long-term complications from prior abuse and not a new episode. Additionally, the data were drawn from academic pediatric hospitals and may not reflect the experience of community and general hospitals.

"Despite the dedicated work of ED and child protection workers, children diagnosed with maltreatment in the ED are at risk for additional victimization and subsequent emergency care for maltreatment, which leads us to suggest that improvements in the child protection apparatus should be considered," Dr. Monuteaux concluded.

The study was internally funded. The authors reported having no relevant financial relationships.

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Abused Children Treated in ED at Risk of Return
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Major Finding: In all, 3% of abused or neglected children treated in the emergency department will return with a second diagnosis of maltreatment, often within a year of the first visit.

Data Source: The retrospective study drew on data from pediatric divisions of 41 U.S. academic medical centers.

Disclosures: The study was internally funded. The authors reported having no relevant financial relationships.

Recurrent non–small-cell lung cancer in elderly patients: a case-based review of current clinical practice

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Management of recurrent non-small cell lung cancer (NSCLC) is a clinical challenge. Around one third of patients who are diagnosed with NSCLC will experience a localregional or advanced stage recurrence. The median time to recurrence from initial diagnosis is 11.5 months. The median age of initial diagnosis of NSCLC is 71 years of age, patients with recurrent disease tend therefore to be even older. Treatment is a challenge, as this elderly patient population tends to have multiple comorbidities, polypharmacy and socioeconomic factors, that have not been accounted for in clinical trials in patients that define our current treatment recommendations. This case-based review outlines some of these challenges and outlines the need for further research.

*For a PDF of the full article, click in the link to the left of this introduction.

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Management of recurrent non-small cell lung cancer (NSCLC) is a clinical challenge. Around one third of patients who are diagnosed with NSCLC will experience a localregional or advanced stage recurrence. The median time to recurrence from initial diagnosis is 11.5 months. The median age of initial diagnosis of NSCLC is 71 years of age, patients with recurrent disease tend therefore to be even older. Treatment is a challenge, as this elderly patient population tends to have multiple comorbidities, polypharmacy and socioeconomic factors, that have not been accounted for in clinical trials in patients that define our current treatment recommendations. This case-based review outlines some of these challenges and outlines the need for further research.

*For a PDF of the full article, click in the link to the left of this introduction.

Management of recurrent non-small cell lung cancer (NSCLC) is a clinical challenge. Around one third of patients who are diagnosed with NSCLC will experience a localregional or advanced stage recurrence. The median time to recurrence from initial diagnosis is 11.5 months. The median age of initial diagnosis of NSCLC is 71 years of age, patients with recurrent disease tend therefore to be even older. Treatment is a challenge, as this elderly patient population tends to have multiple comorbidities, polypharmacy and socioeconomic factors, that have not been accounted for in clinical trials in patients that define our current treatment recommendations. This case-based review outlines some of these challenges and outlines the need for further research.

*For a PDF of the full article, click in the link to the left of this introduction.

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Following Concussions, Give Kids' Brains a Rest

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BOSTON – Children who present to a primary care practice following a head or facial injury must be carefully evaluated for signs and symptoms of concussion, and those with concussion should be advised to give their brains a break, recommended a pediatric injury specialist at the annual meeting of the Pediatric Academic Societies.

Cognitive rest involves limiting "cognitive activity to a level that does not elicit symptoms." For children, this means forgoing computers, video games, texting/social media, reading for school and/or homework, and avoiding noisy or busy environments.

Dr. Kristy B. Arbogast

"The primary focus of pediatric concussion management should be return to cognitive activities and then return to the playing field," Dr. Kristy B. Arbogast said.

A review of records from a large pediatric primary care network showed that 25% of patients with concussion symptoms did not have concussion mentioned in the medical assessment or diagnosis, and nearly half of children in a random sample presented for reevaluation of concussion or persistent concussion symptoms, said Dr. Arbogast, an emergency physician and director of the Pediatric Injury Prevention Program at Children’s Hospital of Philadelphia.

"So-called ‘mild’ traumatic brain injuries are often far from mild. They lead to poor neurological outcomes that can adversely affect a child’s quality of life," she said.

Children with concussion make an estimated 144,000 emergency department visits annually in the United States. As children’s participation in year-round sports has increased, their risk of mild traumatic brain injury (TBI) has also increased, Dr. Arbogast noted.

Concussions among professional athletes receive considerable attention in the popular press, where the stories center on physical recovery and returning to the game. But for school kids, who are at significant risk for learning disabilities, memory problems, and emotional or behavioral changes after a TBI, the focus should be on physical and cognitive rest, she said.

Dr. Arbogast and her colleagues reviewed the concussion management and return-to-school practices of pediatric primary care providers by reviewing records from their hospital’s primary care network.

They looked for data on children aged 5-18 years with any presentation of mild TBI based on ICD-9 codes for skull fracture, concussion, intracranial injury, head injury (unspecified), or facial fracture. The children received initial or continuing care during the study period of July 2010 through June 2011.

The researchers included children who presented with one or more injury characteristics such as amnesia, loss of consciousness, cognitive symptoms (decline in school performance, report of being "in a fog"), emotional symptoms, and physical symptoms or exam findings including eye-tracking problems, headache, nausea/vomiting, poor balance, sleep disturbances, slow reaction times, or visual disturbance. Children with moderate or severe head trauma were excluded from the study.

The investigators randomly selected a sample of 193 patients who met all of the criteria. In all, 51% had a sports-related injury, 8% had previously had a concussion, and 6% had sustained a loss of consciousness.

There was no mention of concussion in the medical assessment or diagnosis of 25% of the sample. Of 94 children who presented for reevaluation of concussion, 33% reported a decline in school performance, 13% said they felt like they were "in a fog," 12% reported vision problems, 12% reported fatigue, and 11% had concentration problems (some reported more than one symptom).

When the authors looked at the written instructions primary care providers gave to the patients, they found that while 54% received return-to-play instructions, only 34% received return-to-school instructions, suggesting that in many cases the practitioners may have failed to recognize the importance of cognitive rest, Dr. Arbogast said. The remaining 12% of patients did not have written instructions documented.

She recommended that clinicians caring for children with suspected concussion ask about all symptoms individually in a systematic fashion, and prescribe a return-to-school protocol with a stepwise approach. The protocol includes a return to the previous step if an action elicits the return of symptoms, sending a standardized letter to notify the child’s school of the plan, and training the child’s parent or guardian to oversee the child’s progression from one step to the next.

The study was funded by the Children’s Hospital of Philadelphia and the University of Pennsylvania, also in Philadelphia. Dr. Arbogast and coinvestigators reported having no conflicts of interest to disclose.

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BOSTON – Children who present to a primary care practice following a head or facial injury must be carefully evaluated for signs and symptoms of concussion, and those with concussion should be advised to give their brains a break, recommended a pediatric injury specialist at the annual meeting of the Pediatric Academic Societies.

Cognitive rest involves limiting "cognitive activity to a level that does not elicit symptoms." For children, this means forgoing computers, video games, texting/social media, reading for school and/or homework, and avoiding noisy or busy environments.

Dr. Kristy B. Arbogast

"The primary focus of pediatric concussion management should be return to cognitive activities and then return to the playing field," Dr. Kristy B. Arbogast said.

A review of records from a large pediatric primary care network showed that 25% of patients with concussion symptoms did not have concussion mentioned in the medical assessment or diagnosis, and nearly half of children in a random sample presented for reevaluation of concussion or persistent concussion symptoms, said Dr. Arbogast, an emergency physician and director of the Pediatric Injury Prevention Program at Children’s Hospital of Philadelphia.

"So-called ‘mild’ traumatic brain injuries are often far from mild. They lead to poor neurological outcomes that can adversely affect a child’s quality of life," she said.

Children with concussion make an estimated 144,000 emergency department visits annually in the United States. As children’s participation in year-round sports has increased, their risk of mild traumatic brain injury (TBI) has also increased, Dr. Arbogast noted.

Concussions among professional athletes receive considerable attention in the popular press, where the stories center on physical recovery and returning to the game. But for school kids, who are at significant risk for learning disabilities, memory problems, and emotional or behavioral changes after a TBI, the focus should be on physical and cognitive rest, she said.

Dr. Arbogast and her colleagues reviewed the concussion management and return-to-school practices of pediatric primary care providers by reviewing records from their hospital’s primary care network.

They looked for data on children aged 5-18 years with any presentation of mild TBI based on ICD-9 codes for skull fracture, concussion, intracranial injury, head injury (unspecified), or facial fracture. The children received initial or continuing care during the study period of July 2010 through June 2011.

The researchers included children who presented with one or more injury characteristics such as amnesia, loss of consciousness, cognitive symptoms (decline in school performance, report of being "in a fog"), emotional symptoms, and physical symptoms or exam findings including eye-tracking problems, headache, nausea/vomiting, poor balance, sleep disturbances, slow reaction times, or visual disturbance. Children with moderate or severe head trauma were excluded from the study.

The investigators randomly selected a sample of 193 patients who met all of the criteria. In all, 51% had a sports-related injury, 8% had previously had a concussion, and 6% had sustained a loss of consciousness.

There was no mention of concussion in the medical assessment or diagnosis of 25% of the sample. Of 94 children who presented for reevaluation of concussion, 33% reported a decline in school performance, 13% said they felt like they were "in a fog," 12% reported vision problems, 12% reported fatigue, and 11% had concentration problems (some reported more than one symptom).

When the authors looked at the written instructions primary care providers gave to the patients, they found that while 54% received return-to-play instructions, only 34% received return-to-school instructions, suggesting that in many cases the practitioners may have failed to recognize the importance of cognitive rest, Dr. Arbogast said. The remaining 12% of patients did not have written instructions documented.

She recommended that clinicians caring for children with suspected concussion ask about all symptoms individually in a systematic fashion, and prescribe a return-to-school protocol with a stepwise approach. The protocol includes a return to the previous step if an action elicits the return of symptoms, sending a standardized letter to notify the child’s school of the plan, and training the child’s parent or guardian to oversee the child’s progression from one step to the next.

The study was funded by the Children’s Hospital of Philadelphia and the University of Pennsylvania, also in Philadelphia. Dr. Arbogast and coinvestigators reported having no conflicts of interest to disclose.

BOSTON – Children who present to a primary care practice following a head or facial injury must be carefully evaluated for signs and symptoms of concussion, and those with concussion should be advised to give their brains a break, recommended a pediatric injury specialist at the annual meeting of the Pediatric Academic Societies.

Cognitive rest involves limiting "cognitive activity to a level that does not elicit symptoms." For children, this means forgoing computers, video games, texting/social media, reading for school and/or homework, and avoiding noisy or busy environments.

Dr. Kristy B. Arbogast

"The primary focus of pediatric concussion management should be return to cognitive activities and then return to the playing field," Dr. Kristy B. Arbogast said.

A review of records from a large pediatric primary care network showed that 25% of patients with concussion symptoms did not have concussion mentioned in the medical assessment or diagnosis, and nearly half of children in a random sample presented for reevaluation of concussion or persistent concussion symptoms, said Dr. Arbogast, an emergency physician and director of the Pediatric Injury Prevention Program at Children’s Hospital of Philadelphia.

"So-called ‘mild’ traumatic brain injuries are often far from mild. They lead to poor neurological outcomes that can adversely affect a child’s quality of life," she said.

Children with concussion make an estimated 144,000 emergency department visits annually in the United States. As children’s participation in year-round sports has increased, their risk of mild traumatic brain injury (TBI) has also increased, Dr. Arbogast noted.

Concussions among professional athletes receive considerable attention in the popular press, where the stories center on physical recovery and returning to the game. But for school kids, who are at significant risk for learning disabilities, memory problems, and emotional or behavioral changes after a TBI, the focus should be on physical and cognitive rest, she said.

Dr. Arbogast and her colleagues reviewed the concussion management and return-to-school practices of pediatric primary care providers by reviewing records from their hospital’s primary care network.

They looked for data on children aged 5-18 years with any presentation of mild TBI based on ICD-9 codes for skull fracture, concussion, intracranial injury, head injury (unspecified), or facial fracture. The children received initial or continuing care during the study period of July 2010 through June 2011.

The researchers included children who presented with one or more injury characteristics such as amnesia, loss of consciousness, cognitive symptoms (decline in school performance, report of being "in a fog"), emotional symptoms, and physical symptoms or exam findings including eye-tracking problems, headache, nausea/vomiting, poor balance, sleep disturbances, slow reaction times, or visual disturbance. Children with moderate or severe head trauma were excluded from the study.

The investigators randomly selected a sample of 193 patients who met all of the criteria. In all, 51% had a sports-related injury, 8% had previously had a concussion, and 6% had sustained a loss of consciousness.

There was no mention of concussion in the medical assessment or diagnosis of 25% of the sample. Of 94 children who presented for reevaluation of concussion, 33% reported a decline in school performance, 13% said they felt like they were "in a fog," 12% reported vision problems, 12% reported fatigue, and 11% had concentration problems (some reported more than one symptom).

When the authors looked at the written instructions primary care providers gave to the patients, they found that while 54% received return-to-play instructions, only 34% received return-to-school instructions, suggesting that in many cases the practitioners may have failed to recognize the importance of cognitive rest, Dr. Arbogast said. The remaining 12% of patients did not have written instructions documented.

She recommended that clinicians caring for children with suspected concussion ask about all symptoms individually in a systematic fashion, and prescribe a return-to-school protocol with a stepwise approach. The protocol includes a return to the previous step if an action elicits the return of symptoms, sending a standardized letter to notify the child’s school of the plan, and training the child’s parent or guardian to oversee the child’s progression from one step to the next.

The study was funded by the Children’s Hospital of Philadelphia and the University of Pennsylvania, also in Philadelphia. Dr. Arbogast and coinvestigators reported having no conflicts of interest to disclose.

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Major Finding: About 25% of children who presented to a primary care practice with concussion symptoms did not have concussion mentioned in the medical assessment or diagnosis.

Data Source: The data were taken from a random sample of records from a pediatric primary care provider network.

Disclosures: The study was funded by the Children’s Hospital of Philadelphia and the University of Pennsylvania. Dr. Arbogast and coinvestigators reported having no conflicts of interest to disclose.

Coping and Psychological Distress in Young Adults With Advanced Cancer

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This study identifies coping strategies utilized by young adults with advanced cancer and examines the relationship between these coping strategies and psychological distress.

ABSTRACT

Background: Little is known about how young adults (YAs) cope with cancer or about the relationship between coping and psychological distress in YAs with advanced cancer.

Objectives: The goals of this study were to identify coping strategies
used by YAs with advanced cancer and examine the relationship between
these coping strategies and psychological distress.

Methods: Using structured clinical interviews with 53 YAs (aged 20–40 years) with advanced cancer, researchers assessed coping methods, depression, anxiety, and grief. A principal components factor analysis identified underlying coping factors. Regression analyses examined the relationship between these coping factors and depression, anxiety, and grief.

Results: Six coping factors emerged and were labeled as proactive, distancing, negative expression, support-seeking, respite-seeking, and acceptance coping. Acceptance and support-seeking coping styles were used most frequently. Coping by negative expression was positively associated with severity of grief after researchers controlled for depression, anxiety, and confounding variables. Support-seeking coping was positively associated with anxiety after researchers controlled for depression and grief.

Limitations: This study was limited by a cross-sectional design, small sample size, and focus on YAs with advanced cancer.

Conclusions: YAs with advanced cancer utilize a range of coping responses that are uniquely related to psychological distress.


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This study identifies coping strategies utilized by young adults with advanced cancer and examines the relationship between these coping strategies and psychological distress.
This study identifies coping strategies utilized by young adults with advanced cancer and examines the relationship between these coping strategies and psychological distress.

ABSTRACT

Background: Little is known about how young adults (YAs) cope with cancer or about the relationship between coping and psychological distress in YAs with advanced cancer.

Objectives: The goals of this study were to identify coping strategies
used by YAs with advanced cancer and examine the relationship between
these coping strategies and psychological distress.

Methods: Using structured clinical interviews with 53 YAs (aged 20–40 years) with advanced cancer, researchers assessed coping methods, depression, anxiety, and grief. A principal components factor analysis identified underlying coping factors. Regression analyses examined the relationship between these coping factors and depression, anxiety, and grief.

Results: Six coping factors emerged and were labeled as proactive, distancing, negative expression, support-seeking, respite-seeking, and acceptance coping. Acceptance and support-seeking coping styles were used most frequently. Coping by negative expression was positively associated with severity of grief after researchers controlled for depression, anxiety, and confounding variables. Support-seeking coping was positively associated with anxiety after researchers controlled for depression and grief.

Limitations: This study was limited by a cross-sectional design, small sample size, and focus on YAs with advanced cancer.

Conclusions: YAs with advanced cancer utilize a range of coping responses that are uniquely related to psychological distress.


To read this article, click on the FILES link at left.

ABSTRACT

Background: Little is known about how young adults (YAs) cope with cancer or about the relationship between coping and psychological distress in YAs with advanced cancer.

Objectives: The goals of this study were to identify coping strategies
used by YAs with advanced cancer and examine the relationship between
these coping strategies and psychological distress.

Methods: Using structured clinical interviews with 53 YAs (aged 20–40 years) with advanced cancer, researchers assessed coping methods, depression, anxiety, and grief. A principal components factor analysis identified underlying coping factors. Regression analyses examined the relationship between these coping factors and depression, anxiety, and grief.

Results: Six coping factors emerged and were labeled as proactive, distancing, negative expression, support-seeking, respite-seeking, and acceptance coping. Acceptance and support-seeking coping styles were used most frequently. Coping by negative expression was positively associated with severity of grief after researchers controlled for depression, anxiety, and confounding variables. Support-seeking coping was positively associated with anxiety after researchers controlled for depression and grief.

Limitations: This study was limited by a cross-sectional design, small sample size, and focus on YAs with advanced cancer.

Conclusions: YAs with advanced cancer utilize a range of coping responses that are uniquely related to psychological distress.


To read this article, click on the FILES link at left.

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Usual and Worst Symptom Severity and Interference With Function in Breast Cancer Survivors

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Background: Breast cancer survivors receive routine medical follow-up but are screened less frequently to detect symptom severity and interference with function in daily life.

Objectives: Among breast cancer survivors, we describe the usual and worst severity of 5 common symptoms and the extent to which these symptoms interfere with general activity and enjoyment of life, we determine the associations among symptoms and the interference items, and we explore associations of interference with function and the most prevalent symptoms.

Methods: The cross-sectional, descriptive 1-page Breast Cancer Survivor Symptom Survey was mailed to breast cancer survivors identified in a clinical database (ONCOBASE). In total, 184/457 (40.3%) surveys were returned and 162 (35.4%) were used. Participants recorded usual and worst severity of 5 symptoms (fatigue, disturbed sleep, pain, distress, and numbness/tingling) and symptom interference with general activity and enjoyment of life during the past 7 days.

Results: Participants reported usual symptom severity as mild and highest for sleep disturbance, followed by fatigue, distress, numbness/tingling, and pain. Participants recorded worst sleep disturbance and fatigue as moderately severe. Higher pain and fatigue were associated with all other symptoms, whereas disturbed sleep and distress were related to all except numbness/tingling. All symptoms interfered with general activity and enjoyment of life. Pain and numbness/tingling were associated with lower function and disturbed sleep, and made a unique contribution to fatigue.

Limitations: Limitations of the study include relatively low response and use of a modification of an established scale.

Conclusion: Symptoms often coexisted and contributed to interference with daily function. Pain was most consistently associated with interference with function and severity of other symptoms.

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Background: Breast cancer survivors receive routine medical follow-up but are screened less frequently to detect symptom severity and interference with function in daily life.

Objectives: Among breast cancer survivors, we describe the usual and worst severity of 5 common symptoms and the extent to which these symptoms interfere with general activity and enjoyment of life, we determine the associations among symptoms and the interference items, and we explore associations of interference with function and the most prevalent symptoms.

Methods: The cross-sectional, descriptive 1-page Breast Cancer Survivor Symptom Survey was mailed to breast cancer survivors identified in a clinical database (ONCOBASE). In total, 184/457 (40.3%) surveys were returned and 162 (35.4%) were used. Participants recorded usual and worst severity of 5 symptoms (fatigue, disturbed sleep, pain, distress, and numbness/tingling) and symptom interference with general activity and enjoyment of life during the past 7 days.

Results: Participants reported usual symptom severity as mild and highest for sleep disturbance, followed by fatigue, distress, numbness/tingling, and pain. Participants recorded worst sleep disturbance and fatigue as moderately severe. Higher pain and fatigue were associated with all other symptoms, whereas disturbed sleep and distress were related to all except numbness/tingling. All symptoms interfered with general activity and enjoyment of life. Pain and numbness/tingling were associated with lower function and disturbed sleep, and made a unique contribution to fatigue.

Limitations: Limitations of the study include relatively low response and use of a modification of an established scale.

Conclusion: Symptoms often coexisted and contributed to interference with daily function. Pain was most consistently associated with interference with function and severity of other symptoms.

To read this study, please click on the Link to the left of this abstract.

ABSTRACT

Background: Breast cancer survivors receive routine medical follow-up but are screened less frequently to detect symptom severity and interference with function in daily life.

Objectives: Among breast cancer survivors, we describe the usual and worst severity of 5 common symptoms and the extent to which these symptoms interfere with general activity and enjoyment of life, we determine the associations among symptoms and the interference items, and we explore associations of interference with function and the most prevalent symptoms.

Methods: The cross-sectional, descriptive 1-page Breast Cancer Survivor Symptom Survey was mailed to breast cancer survivors identified in a clinical database (ONCOBASE). In total, 184/457 (40.3%) surveys were returned and 162 (35.4%) were used. Participants recorded usual and worst severity of 5 symptoms (fatigue, disturbed sleep, pain, distress, and numbness/tingling) and symptom interference with general activity and enjoyment of life during the past 7 days.

Results: Participants reported usual symptom severity as mild and highest for sleep disturbance, followed by fatigue, distress, numbness/tingling, and pain. Participants recorded worst sleep disturbance and fatigue as moderately severe. Higher pain and fatigue were associated with all other symptoms, whereas disturbed sleep and distress were related to all except numbness/tingling. All symptoms interfered with general activity and enjoyment of life. Pain and numbness/tingling were associated with lower function and disturbed sleep, and made a unique contribution to fatigue.

Limitations: Limitations of the study include relatively low response and use of a modification of an established scale.

Conclusion: Symptoms often coexisted and contributed to interference with daily function. Pain was most consistently associated with interference with function and severity of other symptoms.

To read this study, please click on the Link to the left of this abstract.

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DES Seen As Effective for Critically Ischemic Limbs

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LAS VEGAS -- Drug-eluting stents placed below the knee worked well to revascularize critically ischemic limbs in a study of 20 patients. Within a mean 10 months’ follow-up, wounds in 17 of the 20 patients in the study (85%) were healed after stenting, and 16 patients (80%) reported pain relief. Only two needed subsequent amputations.

"Stents are just emerging for below the knee. We certainly have one of the early, large-volume [series], with reasonable follow-up," said Dr. Michael Wilderman, a vascular surgeon at Hackensack (N.J.) University Medical Center.

Before they were stented, the patients had, on average, Rutherford stage 4.9 disease, indicating pain at rest and ischemic toe or foot ulcers. The majority had already lost some tissue, and seven (35%) had cellulitis.

Diabetes, hypertension, heart disease, and other comorbidities – plus an average age of 79 years – were found to make open repair too risky, according to Dr. Wilderman, who spoke at the annual meeting of the Society for Clinical Vascular Surgery.

The 25 lesions, in 22 limbs, were located in the below-knee popliteal artery, tibioperoneal trunk, anterior tibial artery, peroneal artery, and posterior tibial artery. Five lesions threatened distal reversed saphenous vein grafts.

The researchers placed everolimus-eluting stents (average diameter, 3 mm) using standard percutaneous techniques. The lesions they addressed were short, and thus could be adequately covered with a 3-cm stent.

Complications were minimal: One patient had a groin hematoma, and another had a puncture-site pseudoaneurysm.

"Initially, we were not planning to stent the first couple we did. We were just going to balloon and see what happens, because that’s what everyone else does," Dr. Wilderman said.

However, because the vessels did not look good angiographically, his team put a stent in and the patients did well. "We found that if we had a short, focal [lesion] that we could stent, we would just stent it," he explained.

Because drug-eluting stents work well for coronary arteries, and tibial arteries share similar histology and luminal diameters, it made sense to try them for below-the-knee ischemia, he said.

Asked for comment, Dr. George Meier, chief of vascular surgery at the University of Cincinnati, noted that coronary drug-eluting stents have been used off label below the knee before. "It’s something we occasionally do in recurrent lesions when we have nothing else to do. The difficulty is following it out long enough to see if it makes an impact," he said.

Dr. Wilderman and Dr. Meier reported that they had no relevant financial disclosures.

Body

Drug-eluting stents have been used in calf vessel by a number of groups for the reasons outlined by the Hackensack University Medical CenterTeam. However, while appealing, there is currently no data to support their use and extra cost. The haemodynamic environment in the coronary arteries is entirely different to that of a lower limb artery and so it is not acceptable to extrapolate results from cardiac interventions to the leg.

The data in this report does little to clarify the situation. While clinical outcomes are the most important factor for the patient, in a small non-randomized observational study they are of little value on their own. It would be helpful to know more about the lesions, in particular why they were selected for drug eluting stents and the immediate hemodynamic effect. The putative reason for using a drug-eluting stent is to reduce restenosis and re-occlusion so without information on these factors the report is of limited value.

With increasing health care costs in a financially challenged world economy, all therapies are likely to come under scrutiny not only for clinical effectiveness but for cost effectiveness as well. The challenge is to produce high quality data in both these areas to support the use of drug -eluting stents before health commissioners refuse to reimburse for the therapy.

Professor Cliff P. Shearman of the University of Southampton, UK, is an associate medical editor for Vascular Specialist.

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Drug-eluting stents have been used in calf vessel by a number of groups for the reasons outlined by the Hackensack University Medical CenterTeam. However, while appealing, there is currently no data to support their use and extra cost. The haemodynamic environment in the coronary arteries is entirely different to that of a lower limb artery and so it is not acceptable to extrapolate results from cardiac interventions to the leg.

The data in this report does little to clarify the situation. While clinical outcomes are the most important factor for the patient, in a small non-randomized observational study they are of little value on their own. It would be helpful to know more about the lesions, in particular why they were selected for drug eluting stents and the immediate hemodynamic effect. The putative reason for using a drug-eluting stent is to reduce restenosis and re-occlusion so without information on these factors the report is of limited value.

With increasing health care costs in a financially challenged world economy, all therapies are likely to come under scrutiny not only for clinical effectiveness but for cost effectiveness as well. The challenge is to produce high quality data in both these areas to support the use of drug -eluting stents before health commissioners refuse to reimburse for the therapy.

Professor Cliff P. Shearman of the University of Southampton, UK, is an associate medical editor for Vascular Specialist.

Body

Drug-eluting stents have been used in calf vessel by a number of groups for the reasons outlined by the Hackensack University Medical CenterTeam. However, while appealing, there is currently no data to support their use and extra cost. The haemodynamic environment in the coronary arteries is entirely different to that of a lower limb artery and so it is not acceptable to extrapolate results from cardiac interventions to the leg.

The data in this report does little to clarify the situation. While clinical outcomes are the most important factor for the patient, in a small non-randomized observational study they are of little value on their own. It would be helpful to know more about the lesions, in particular why they were selected for drug eluting stents and the immediate hemodynamic effect. The putative reason for using a drug-eluting stent is to reduce restenosis and re-occlusion so without information on these factors the report is of limited value.

With increasing health care costs in a financially challenged world economy, all therapies are likely to come under scrutiny not only for clinical effectiveness but for cost effectiveness as well. The challenge is to produce high quality data in both these areas to support the use of drug -eluting stents before health commissioners refuse to reimburse for the therapy.

Professor Cliff P. Shearman of the University of Southampton, UK, is an associate medical editor for Vascular Specialist.

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LAS VEGAS -- Drug-eluting stents placed below the knee worked well to revascularize critically ischemic limbs in a study of 20 patients. Within a mean 10 months’ follow-up, wounds in 17 of the 20 patients in the study (85%) were healed after stenting, and 16 patients (80%) reported pain relief. Only two needed subsequent amputations.

"Stents are just emerging for below the knee. We certainly have one of the early, large-volume [series], with reasonable follow-up," said Dr. Michael Wilderman, a vascular surgeon at Hackensack (N.J.) University Medical Center.

Before they were stented, the patients had, on average, Rutherford stage 4.9 disease, indicating pain at rest and ischemic toe or foot ulcers. The majority had already lost some tissue, and seven (35%) had cellulitis.

Diabetes, hypertension, heart disease, and other comorbidities – plus an average age of 79 years – were found to make open repair too risky, according to Dr. Wilderman, who spoke at the annual meeting of the Society for Clinical Vascular Surgery.

The 25 lesions, in 22 limbs, were located in the below-knee popliteal artery, tibioperoneal trunk, anterior tibial artery, peroneal artery, and posterior tibial artery. Five lesions threatened distal reversed saphenous vein grafts.

The researchers placed everolimus-eluting stents (average diameter, 3 mm) using standard percutaneous techniques. The lesions they addressed were short, and thus could be adequately covered with a 3-cm stent.

Complications were minimal: One patient had a groin hematoma, and another had a puncture-site pseudoaneurysm.

"Initially, we were not planning to stent the first couple we did. We were just going to balloon and see what happens, because that’s what everyone else does," Dr. Wilderman said.

However, because the vessels did not look good angiographically, his team put a stent in and the patients did well. "We found that if we had a short, focal [lesion] that we could stent, we would just stent it," he explained.

Because drug-eluting stents work well for coronary arteries, and tibial arteries share similar histology and luminal diameters, it made sense to try them for below-the-knee ischemia, he said.

Asked for comment, Dr. George Meier, chief of vascular surgery at the University of Cincinnati, noted that coronary drug-eluting stents have been used off label below the knee before. "It’s something we occasionally do in recurrent lesions when we have nothing else to do. The difficulty is following it out long enough to see if it makes an impact," he said.

Dr. Wilderman and Dr. Meier reported that they had no relevant financial disclosures.

LAS VEGAS -- Drug-eluting stents placed below the knee worked well to revascularize critically ischemic limbs in a study of 20 patients. Within a mean 10 months’ follow-up, wounds in 17 of the 20 patients in the study (85%) were healed after stenting, and 16 patients (80%) reported pain relief. Only two needed subsequent amputations.

"Stents are just emerging for below the knee. We certainly have one of the early, large-volume [series], with reasonable follow-up," said Dr. Michael Wilderman, a vascular surgeon at Hackensack (N.J.) University Medical Center.

Before they were stented, the patients had, on average, Rutherford stage 4.9 disease, indicating pain at rest and ischemic toe or foot ulcers. The majority had already lost some tissue, and seven (35%) had cellulitis.

Diabetes, hypertension, heart disease, and other comorbidities – plus an average age of 79 years – were found to make open repair too risky, according to Dr. Wilderman, who spoke at the annual meeting of the Society for Clinical Vascular Surgery.

The 25 lesions, in 22 limbs, were located in the below-knee popliteal artery, tibioperoneal trunk, anterior tibial artery, peroneal artery, and posterior tibial artery. Five lesions threatened distal reversed saphenous vein grafts.

The researchers placed everolimus-eluting stents (average diameter, 3 mm) using standard percutaneous techniques. The lesions they addressed were short, and thus could be adequately covered with a 3-cm stent.

Complications were minimal: One patient had a groin hematoma, and another had a puncture-site pseudoaneurysm.

"Initially, we were not planning to stent the first couple we did. We were just going to balloon and see what happens, because that’s what everyone else does," Dr. Wilderman said.

However, because the vessels did not look good angiographically, his team put a stent in and the patients did well. "We found that if we had a short, focal [lesion] that we could stent, we would just stent it," he explained.

Because drug-eluting stents work well for coronary arteries, and tibial arteries share similar histology and luminal diameters, it made sense to try them for below-the-knee ischemia, he said.

Asked for comment, Dr. George Meier, chief of vascular surgery at the University of Cincinnati, noted that coronary drug-eluting stents have been used off label below the knee before. "It’s something we occasionally do in recurrent lesions when we have nothing else to do. The difficulty is following it out long enough to see if it makes an impact," he said.

Dr. Wilderman and Dr. Meier reported that they had no relevant financial disclosures.

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Major Finding: In a small series, drug-eluting stents below the knee helped heal foot ulcers and bring pain relief to a majority (16 of 20) of patients with critical limb ischemia.

Data Source: The data were obtained from a retrospectively reviewed case series at Hackensack (N.J.) University Medical Center.

Disclosures: Dr. Wilderman and Dr. Meier said they had no relevant disclosures.

Comparing Specialties For Lower Endovascular Therapy

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Endovascular lower-extremity revascularization by vascular specialists resulted in more transfusions and ICU use, as well as a longer hospital stay, more repeat revascularization procedures and amputations, and higher costs, compared with the same procedures performed by interventional radiologists, according to the results of a large database analysis of the Medicare 5% Standard Analytical Files.

Dr. Abdul M. Zafar of the Vascular Disease Research Center, Brown University Alpert Medical School, Providence, and his colleagues extracted claims for endovascularlower extremity revascularization (ELER) index procedures using Current Procedural Terminology (CPT) codes in the years 2005 through 2007.

They recorded the unique IDs of the 15,455 patients who underwent these procedures and for whom an inpatient or outpatient claim corresponding to the index procedure claim was available. This comprised all claims for percutaneous angioplasty, atherectomy, and stent implantation of lower extremity arteries.

The self-designated specialty code of the physician performing the procedure was used to determine specialist type: vascular surgeons (VS), interventional radiologists (IR); interventional cardiologists (IC); and "other."

After excluding patients who might have undergone hybrid procedures and those who underwent thrombolysis procedures in the same year as the index procedure, the final sample of 14,608 patients was analyzed for the following outcomes: length of hospital stay; use of intensive care unit (ICU) services; transfusions; in-hospital mortality; and repeat intervention (defined as any ELER, open lower-extremity revascularization, or amputation of the lower extremity).

The researchers built risk-adjusted logistic regression models by using maximum-likelihood estimates to compare various patient outcomes across different specialties, and they used a linear regression model employing ordinary least squares to analyze length of stay. Cost analysis was performed using a linear regression model based on the least-squares approach. All models were adjusted for age, sex, race, admission type (emergency or ambulatory), and other comorbidities using the Elixhauser comorbidities software available from the Agency for Healthcare Research and Quality. Other regression models that included the International Classification of Disease-9 code for disease severity were developed, but were less predictive and had lower R2 values, according to the authors. All logistic regression models passed the goodness-of-fit test at the 99% confidence level. In addition, linear regression models were also found to be satisfactory at the same level, according to the authors.

Within the study, there were 3,565 index procedures done by IRs; 5,489 by ICs; 5,358 by VSs; and 196 performed by "other" specialties (J. Vasc. Interven. Radiol 2012;23:3-9).

Dr. Zafar and his colleagues reported that VS outcomes were significantly worse than when the procedures were performed by an IR or IC. IRs had a 32% lower likelihood of ICU use (P less than .001) and a 37% lower likelihood of repeat lower-extremity revascularization or amputation (P less than .001) compared with VS. "Although statistical significance was not reached, both transfusion use and in-hospital mortality were 19% less likely after IRs performed procedures compared with VSs (P = .113 and P =.351, respectively)."

"Vascular surgeons were the only specialists with post-index procedure length of stay exceeding 3 days, significantly longer than observed for other specialties. The adjusted average 1-year costs per index procedure were 9% greater for vascular surgeons than for interventional radiologists ($19,012 vs. $17,640)," they said.

"The reasons for worse outcomes among VSs are not known, but may be related to insufficient training in catheter-based interventions as a result of the extensive time learning and practicing open surgical procedure compared with IRs and ICs, whose focus is catheter interventions," they said. "Medicare data indicate that patients who need lower-extremity endovascular revascularization services experience shorter hospital stays, require less transfusions and ICU services, have lower in-hospital mortality rates, and have much less chance of a subsequent revascularization or amputation within one year if treated by an IR rather than a VS," they concluded.

The study was supported by a grant from the Society of Interventional Radiology and internal funds from the Vascular Disease Research Center. One authors received research funding from Cordis/Johnson&Johnson, and Abbott Vascular and consulting for Microvention/Terumo.

Body

I note that the work was supported by a grant from the Society of Interventional Radiologists (SIR), and that the corresponding author is the current SIR President. The manuscript itself is so methodologically flawed ....its manipulated data alone would be enough to call it into question. The introductory paragraph states the authors’ message is that vascular surgeons offer endovascular procedures related to economic greed. This repugnant accusation with respect to monetary concerns motivating the practice of vascular surgeons (VS) represents a nadir of professional conduct.

The theme is continued in the Discussion where the authors make their ridiculous contention that vascular surgeons offering both open and endovascular procedures represents an inherent conflict of interest... against Medicare beneficiaries to capture more revenue. [In fact,] since VS are the only specialists offering both open and endovascular options to patients, it must be apparent that VS make treatment recommendations without prejudice or bias to any particular mode of intervention.

As in other vascular territories, treatment of leg occlusive disease has largely shifted from open to endovascular procedures; and Interventional Radiologists (IR) "market share" for such procedures declined from 67% in 1996 to less than 20% in 2006. As in other vascular territories, patients are best served when VS who provide comprehensive care and longitudinal follow-up, also manage their intervention irrespective of its nature. It is certainly true that SVS and others engineered a retraining of the VS workforce over the past 15 years, and that in terms of endovascular training, the paradigm has shifted. VS trainees have had mandated endovascular training with case numbers requirements for a decade, and their experience in this realm now far exceeds that of IR fellows.

The selection of endpoints, such as transfusion, use of intensive care services, and length of stay are often irrelevant (in hospitalized patients) to an endovascular procedure per se; rather, they reflect the overall complexity and/or complicating patient comorbidities that may dominate the clinical picture. Nor can the Medicare database used in this study discern the temporal relationship of endpoints such as ICU stay to the vascular intervention. In consideration of the mortality endpoint, they repeatedly call attention to the "19% higher mortality with vascular surgeons," but note this difference was not significant. In addition, the selection of a subsequent revascularization or amputation as a surrogate for procedural quality introduces the single glaring flaw in this manuscript, viz. the failure to include specifics of the indication for vascular intervention. These data are available in the Medicare database, but we are told that inclusion of such data in regression models were "less predictive and had a low R-square values." The authors manipulating of the data with what we consider illogical surrogates for procedural expertise may be in response to prior work, using the NIS database that demonstrated both procedural mortality and iatrogenic arterial injury were significantly higher for IR and IC as compared to VS. Indeed this earlier report also utilized appropriate risk adjusted multivariate analyses, which is inherently lacking in the JVIR article. Furthermore, it is well documented that VS are significantly more likely to treat patients with rest pain and tissue loss, as compared to claudicants.

It is also documented and intuitively logical that virtually all of the endpoints that the authors consider, including mortality, LOS, amputation rates, and resource consumption are significantly higher in patients treated for limb-threatening ischemia as opposed to claudication.

The analysis was adjusted only for age, sex, race, admission type, and a general co-morbidity measure (Elixhauser method), which accounts for 30 variables including inconsequential considerations, such as weight loss and hypothyroidism, but not for the indication for the procedure. Thus when used as a total score, this method includes a great deal of ‘noise,’ making it largely irrelevant to treatment outcomes in patients with PAD. Such indices were developed to be used at administrative levels in comparing hospital or health systems rather than individual patient outcomes.

Finally, the use of the endpoint of repeat revascularization or any amputation as the surrogate for quality of the index procedure is patently absurd. A digital or forefoot amputation is often performed subsequent to a lower extremity revascularization in patients with tissue loss. Furthermore, secondary interventions after infrainguinal endovascular procedures are commonly required to maintain secondary (reported ranges 15-30%) patency.

To those with any knowledge of vascular disease, this article will be seen as self-serving and scientifically flawed.

Dr. Richard P. Cambria, President, Society for Vascular Surgery

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I note that the work was supported by a grant from the Society of Interventional Radiologists (SIR), and that the corresponding author is the current SIR President. The manuscript itself is so methodologically flawed ....its manipulated data alone would be enough to call it into question. The introductory paragraph states the authors’ message is that vascular surgeons offer endovascular procedures related to economic greed. This repugnant accusation with respect to monetary concerns motivating the practice of vascular surgeons (VS) represents a nadir of professional conduct.

The theme is continued in the Discussion where the authors make their ridiculous contention that vascular surgeons offering both open and endovascular procedures represents an inherent conflict of interest... against Medicare beneficiaries to capture more revenue. [In fact,] since VS are the only specialists offering both open and endovascular options to patients, it must be apparent that VS make treatment recommendations without prejudice or bias to any particular mode of intervention.

As in other vascular territories, treatment of leg occlusive disease has largely shifted from open to endovascular procedures; and Interventional Radiologists (IR) "market share" for such procedures declined from 67% in 1996 to less than 20% in 2006. As in other vascular territories, patients are best served when VS who provide comprehensive care and longitudinal follow-up, also manage their intervention irrespective of its nature. It is certainly true that SVS and others engineered a retraining of the VS workforce over the past 15 years, and that in terms of endovascular training, the paradigm has shifted. VS trainees have had mandated endovascular training with case numbers requirements for a decade, and their experience in this realm now far exceeds that of IR fellows.

The selection of endpoints, such as transfusion, use of intensive care services, and length of stay are often irrelevant (in hospitalized patients) to an endovascular procedure per se; rather, they reflect the overall complexity and/or complicating patient comorbidities that may dominate the clinical picture. Nor can the Medicare database used in this study discern the temporal relationship of endpoints such as ICU stay to the vascular intervention. In consideration of the mortality endpoint, they repeatedly call attention to the "19% higher mortality with vascular surgeons," but note this difference was not significant. In addition, the selection of a subsequent revascularization or amputation as a surrogate for procedural quality introduces the single glaring flaw in this manuscript, viz. the failure to include specifics of the indication for vascular intervention. These data are available in the Medicare database, but we are told that inclusion of such data in regression models were "less predictive and had a low R-square values." The authors manipulating of the data with what we consider illogical surrogates for procedural expertise may be in response to prior work, using the NIS database that demonstrated both procedural mortality and iatrogenic arterial injury were significantly higher for IR and IC as compared to VS. Indeed this earlier report also utilized appropriate risk adjusted multivariate analyses, which is inherently lacking in the JVIR article. Furthermore, it is well documented that VS are significantly more likely to treat patients with rest pain and tissue loss, as compared to claudicants.

It is also documented and intuitively logical that virtually all of the endpoints that the authors consider, including mortality, LOS, amputation rates, and resource consumption are significantly higher in patients treated for limb-threatening ischemia as opposed to claudication.

The analysis was adjusted only for age, sex, race, admission type, and a general co-morbidity measure (Elixhauser method), which accounts for 30 variables including inconsequential considerations, such as weight loss and hypothyroidism, but not for the indication for the procedure. Thus when used as a total score, this method includes a great deal of ‘noise,’ making it largely irrelevant to treatment outcomes in patients with PAD. Such indices were developed to be used at administrative levels in comparing hospital or health systems rather than individual patient outcomes.

Finally, the use of the endpoint of repeat revascularization or any amputation as the surrogate for quality of the index procedure is patently absurd. A digital or forefoot amputation is often performed subsequent to a lower extremity revascularization in patients with tissue loss. Furthermore, secondary interventions after infrainguinal endovascular procedures are commonly required to maintain secondary (reported ranges 15-30%) patency.

To those with any knowledge of vascular disease, this article will be seen as self-serving and scientifically flawed.

Dr. Richard P. Cambria, President, Society for Vascular Surgery

Body

I note that the work was supported by a grant from the Society of Interventional Radiologists (SIR), and that the corresponding author is the current SIR President. The manuscript itself is so methodologically flawed ....its manipulated data alone would be enough to call it into question. The introductory paragraph states the authors’ message is that vascular surgeons offer endovascular procedures related to economic greed. This repugnant accusation with respect to monetary concerns motivating the practice of vascular surgeons (VS) represents a nadir of professional conduct.

The theme is continued in the Discussion where the authors make their ridiculous contention that vascular surgeons offering both open and endovascular procedures represents an inherent conflict of interest... against Medicare beneficiaries to capture more revenue. [In fact,] since VS are the only specialists offering both open and endovascular options to patients, it must be apparent that VS make treatment recommendations without prejudice or bias to any particular mode of intervention.

As in other vascular territories, treatment of leg occlusive disease has largely shifted from open to endovascular procedures; and Interventional Radiologists (IR) "market share" for such procedures declined from 67% in 1996 to less than 20% in 2006. As in other vascular territories, patients are best served when VS who provide comprehensive care and longitudinal follow-up, also manage their intervention irrespective of its nature. It is certainly true that SVS and others engineered a retraining of the VS workforce over the past 15 years, and that in terms of endovascular training, the paradigm has shifted. VS trainees have had mandated endovascular training with case numbers requirements for a decade, and their experience in this realm now far exceeds that of IR fellows.

The selection of endpoints, such as transfusion, use of intensive care services, and length of stay are often irrelevant (in hospitalized patients) to an endovascular procedure per se; rather, they reflect the overall complexity and/or complicating patient comorbidities that may dominate the clinical picture. Nor can the Medicare database used in this study discern the temporal relationship of endpoints such as ICU stay to the vascular intervention. In consideration of the mortality endpoint, they repeatedly call attention to the "19% higher mortality with vascular surgeons," but note this difference was not significant. In addition, the selection of a subsequent revascularization or amputation as a surrogate for procedural quality introduces the single glaring flaw in this manuscript, viz. the failure to include specifics of the indication for vascular intervention. These data are available in the Medicare database, but we are told that inclusion of such data in regression models were "less predictive and had a low R-square values." The authors manipulating of the data with what we consider illogical surrogates for procedural expertise may be in response to prior work, using the NIS database that demonstrated both procedural mortality and iatrogenic arterial injury were significantly higher for IR and IC as compared to VS. Indeed this earlier report also utilized appropriate risk adjusted multivariate analyses, which is inherently lacking in the JVIR article. Furthermore, it is well documented that VS are significantly more likely to treat patients with rest pain and tissue loss, as compared to claudicants.

It is also documented and intuitively logical that virtually all of the endpoints that the authors consider, including mortality, LOS, amputation rates, and resource consumption are significantly higher in patients treated for limb-threatening ischemia as opposed to claudication.

The analysis was adjusted only for age, sex, race, admission type, and a general co-morbidity measure (Elixhauser method), which accounts for 30 variables including inconsequential considerations, such as weight loss and hypothyroidism, but not for the indication for the procedure. Thus when used as a total score, this method includes a great deal of ‘noise,’ making it largely irrelevant to treatment outcomes in patients with PAD. Such indices were developed to be used at administrative levels in comparing hospital or health systems rather than individual patient outcomes.

Finally, the use of the endpoint of repeat revascularization or any amputation as the surrogate for quality of the index procedure is patently absurd. A digital or forefoot amputation is often performed subsequent to a lower extremity revascularization in patients with tissue loss. Furthermore, secondary interventions after infrainguinal endovascular procedures are commonly required to maintain secondary (reported ranges 15-30%) patency.

To those with any knowledge of vascular disease, this article will be seen as self-serving and scientifically flawed.

Dr. Richard P. Cambria, President, Society for Vascular Surgery

Title
SVS Challenges Results
SVS Challenges Results

Endovascular lower-extremity revascularization by vascular specialists resulted in more transfusions and ICU use, as well as a longer hospital stay, more repeat revascularization procedures and amputations, and higher costs, compared with the same procedures performed by interventional radiologists, according to the results of a large database analysis of the Medicare 5% Standard Analytical Files.

Dr. Abdul M. Zafar of the Vascular Disease Research Center, Brown University Alpert Medical School, Providence, and his colleagues extracted claims for endovascularlower extremity revascularization (ELER) index procedures using Current Procedural Terminology (CPT) codes in the years 2005 through 2007.

They recorded the unique IDs of the 15,455 patients who underwent these procedures and for whom an inpatient or outpatient claim corresponding to the index procedure claim was available. This comprised all claims for percutaneous angioplasty, atherectomy, and stent implantation of lower extremity arteries.

The self-designated specialty code of the physician performing the procedure was used to determine specialist type: vascular surgeons (VS), interventional radiologists (IR); interventional cardiologists (IC); and "other."

After excluding patients who might have undergone hybrid procedures and those who underwent thrombolysis procedures in the same year as the index procedure, the final sample of 14,608 patients was analyzed for the following outcomes: length of hospital stay; use of intensive care unit (ICU) services; transfusions; in-hospital mortality; and repeat intervention (defined as any ELER, open lower-extremity revascularization, or amputation of the lower extremity).

The researchers built risk-adjusted logistic regression models by using maximum-likelihood estimates to compare various patient outcomes across different specialties, and they used a linear regression model employing ordinary least squares to analyze length of stay. Cost analysis was performed using a linear regression model based on the least-squares approach. All models were adjusted for age, sex, race, admission type (emergency or ambulatory), and other comorbidities using the Elixhauser comorbidities software available from the Agency for Healthcare Research and Quality. Other regression models that included the International Classification of Disease-9 code for disease severity were developed, but were less predictive and had lower R2 values, according to the authors. All logistic regression models passed the goodness-of-fit test at the 99% confidence level. In addition, linear regression models were also found to be satisfactory at the same level, according to the authors.

Within the study, there were 3,565 index procedures done by IRs; 5,489 by ICs; 5,358 by VSs; and 196 performed by "other" specialties (J. Vasc. Interven. Radiol 2012;23:3-9).

Dr. Zafar and his colleagues reported that VS outcomes were significantly worse than when the procedures were performed by an IR or IC. IRs had a 32% lower likelihood of ICU use (P less than .001) and a 37% lower likelihood of repeat lower-extremity revascularization or amputation (P less than .001) compared with VS. "Although statistical significance was not reached, both transfusion use and in-hospital mortality were 19% less likely after IRs performed procedures compared with VSs (P = .113 and P =.351, respectively)."

"Vascular surgeons were the only specialists with post-index procedure length of stay exceeding 3 days, significantly longer than observed for other specialties. The adjusted average 1-year costs per index procedure were 9% greater for vascular surgeons than for interventional radiologists ($19,012 vs. $17,640)," they said.

"The reasons for worse outcomes among VSs are not known, but may be related to insufficient training in catheter-based interventions as a result of the extensive time learning and practicing open surgical procedure compared with IRs and ICs, whose focus is catheter interventions," they said. "Medicare data indicate that patients who need lower-extremity endovascular revascularization services experience shorter hospital stays, require less transfusions and ICU services, have lower in-hospital mortality rates, and have much less chance of a subsequent revascularization or amputation within one year if treated by an IR rather than a VS," they concluded.

The study was supported by a grant from the Society of Interventional Radiology and internal funds from the Vascular Disease Research Center. One authors received research funding from Cordis/Johnson&Johnson, and Abbott Vascular and consulting for Microvention/Terumo.

Endovascular lower-extremity revascularization by vascular specialists resulted in more transfusions and ICU use, as well as a longer hospital stay, more repeat revascularization procedures and amputations, and higher costs, compared with the same procedures performed by interventional radiologists, according to the results of a large database analysis of the Medicare 5% Standard Analytical Files.

Dr. Abdul M. Zafar of the Vascular Disease Research Center, Brown University Alpert Medical School, Providence, and his colleagues extracted claims for endovascularlower extremity revascularization (ELER) index procedures using Current Procedural Terminology (CPT) codes in the years 2005 through 2007.

They recorded the unique IDs of the 15,455 patients who underwent these procedures and for whom an inpatient or outpatient claim corresponding to the index procedure claim was available. This comprised all claims for percutaneous angioplasty, atherectomy, and stent implantation of lower extremity arteries.

The self-designated specialty code of the physician performing the procedure was used to determine specialist type: vascular surgeons (VS), interventional radiologists (IR); interventional cardiologists (IC); and "other."

After excluding patients who might have undergone hybrid procedures and those who underwent thrombolysis procedures in the same year as the index procedure, the final sample of 14,608 patients was analyzed for the following outcomes: length of hospital stay; use of intensive care unit (ICU) services; transfusions; in-hospital mortality; and repeat intervention (defined as any ELER, open lower-extremity revascularization, or amputation of the lower extremity).

The researchers built risk-adjusted logistic regression models by using maximum-likelihood estimates to compare various patient outcomes across different specialties, and they used a linear regression model employing ordinary least squares to analyze length of stay. Cost analysis was performed using a linear regression model based on the least-squares approach. All models were adjusted for age, sex, race, admission type (emergency or ambulatory), and other comorbidities using the Elixhauser comorbidities software available from the Agency for Healthcare Research and Quality. Other regression models that included the International Classification of Disease-9 code for disease severity were developed, but were less predictive and had lower R2 values, according to the authors. All logistic regression models passed the goodness-of-fit test at the 99% confidence level. In addition, linear regression models were also found to be satisfactory at the same level, according to the authors.

Within the study, there were 3,565 index procedures done by IRs; 5,489 by ICs; 5,358 by VSs; and 196 performed by "other" specialties (J. Vasc. Interven. Radiol 2012;23:3-9).

Dr. Zafar and his colleagues reported that VS outcomes were significantly worse than when the procedures were performed by an IR or IC. IRs had a 32% lower likelihood of ICU use (P less than .001) and a 37% lower likelihood of repeat lower-extremity revascularization or amputation (P less than .001) compared with VS. "Although statistical significance was not reached, both transfusion use and in-hospital mortality were 19% less likely after IRs performed procedures compared with VSs (P = .113 and P =.351, respectively)."

"Vascular surgeons were the only specialists with post-index procedure length of stay exceeding 3 days, significantly longer than observed for other specialties. The adjusted average 1-year costs per index procedure were 9% greater for vascular surgeons than for interventional radiologists ($19,012 vs. $17,640)," they said.

"The reasons for worse outcomes among VSs are not known, but may be related to insufficient training in catheter-based interventions as a result of the extensive time learning and practicing open surgical procedure compared with IRs and ICs, whose focus is catheter interventions," they said. "Medicare data indicate that patients who need lower-extremity endovascular revascularization services experience shorter hospital stays, require less transfusions and ICU services, have lower in-hospital mortality rates, and have much less chance of a subsequent revascularization or amputation within one year if treated by an IR rather than a VS," they concluded.

The study was supported by a grant from the Society of Interventional Radiology and internal funds from the Vascular Disease Research Center. One authors received research funding from Cordis/Johnson&Johnson, and Abbott Vascular and consulting for Microvention/Terumo.

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