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FDA approves CML drug for home administration
The US Food and Drug Administration (FDA) has expanded the approval of omacetaxine mepesuccinate (Synribo) to include home administration.
The drug is already FDA-approved to treat adults with chronic or accelerated phase chronic myeloid leukemia (CML) who do not respond to or cannot tolerate 2 or more tyrosine kinase inhibitors.
The new approval allows CML patients to self-administer subcutaneous injections of omacetaxine mepesuccinate at home.
“It had been necessary for adults living with chronic or accelerated phase CML who are prescribed Synribo to travel to their doctor’s office twice a day for 2 weeks, which can be extremely burdensome and inconvenient to both patients and their caregivers,” said Meir Wetzler, MD, FACP, Chief of the Leukemia Section at Roswell Park Cancer Institute in Buffalo, New York.
“Now, physicians can decide if their patients are candidates for self-administration and, if so, provide their patients with guidance on how to properly administer reconstituted Synribo in the home.”
The drug’s maker, Teva Pharmaceutical Industries, Ltd., is working to finalize a pharmacy support program that will help facilitate successful home administration of omacetaxine mepesuccinate. The program is expected to “go live” this month or next.
About omacetaxine mepesuccinate
Omacetaxine mepesuccinate is a protein synthesis inhibitor. Although the drug’s mechanism of action is not fully understood, it is known to prevent the production of Bcr-Abl and Mcl-1, which help drive CML.
In October 2012, the FDA granted omacetaxine mepesuccinate accelerated approval for the treatment of adult patients with chronic or accelerated phase CML with resistance and/or intolerance to 2 or more tyrosine kinase inhibitors. Omacetaxine mepesuccinate gained full FDA approval in February.
The drug has been associated with severe and fatal myelosuppression, including thrombocytopenia, neutropenia, and anemia in some patients. So healthcare professionals should monitor patients’ complete blood counts weekly during induction and initial maintenance cycles and every 2 weeks during later maintenance cycles, as clinically indicated.
Omacetaxine mepesuccinate has been known to cause severe thrombocytopenia, which increases the risk of hemorrhage. Fatalities from cerebral hemorrhage have occurred. And severe, non-fatal gastrointestinal hemorrhages have occurred.
So healthcare professionals should monitor platelet counts as part of the complete blood count as recommended. Patients should not receive anticoagulants, aspirin, or non-steroidal anti-inflammatory drugs when their platelet counts are <50,000/μL, as these drugs may increase the risk of bleeding.
Omacetaxine mepesuccinate can induce glucose intolerance as well. So healthcare professionals should monitor blood glucose levels frequently, especially in patients with diabetes or risk factors for diabetes. Patients with poorly controlled diabetes mellitus should not receive omacetaxine mepesuccinate until good glycemic control has been established.
Omacetaxine mepesuccinate can cause fetal harm when administered to a pregnant woman. So women should be advised to avoid becoming pregnant while using the drug.
For more details on omacetaxine mepesuccinate, see the full prescribing information.
The US Food and Drug Administration (FDA) has expanded the approval of omacetaxine mepesuccinate (Synribo) to include home administration.
The drug is already FDA-approved to treat adults with chronic or accelerated phase chronic myeloid leukemia (CML) who do not respond to or cannot tolerate 2 or more tyrosine kinase inhibitors.
The new approval allows CML patients to self-administer subcutaneous injections of omacetaxine mepesuccinate at home.
“It had been necessary for adults living with chronic or accelerated phase CML who are prescribed Synribo to travel to their doctor’s office twice a day for 2 weeks, which can be extremely burdensome and inconvenient to both patients and their caregivers,” said Meir Wetzler, MD, FACP, Chief of the Leukemia Section at Roswell Park Cancer Institute in Buffalo, New York.
“Now, physicians can decide if their patients are candidates for self-administration and, if so, provide their patients with guidance on how to properly administer reconstituted Synribo in the home.”
The drug’s maker, Teva Pharmaceutical Industries, Ltd., is working to finalize a pharmacy support program that will help facilitate successful home administration of omacetaxine mepesuccinate. The program is expected to “go live” this month or next.
About omacetaxine mepesuccinate
Omacetaxine mepesuccinate is a protein synthesis inhibitor. Although the drug’s mechanism of action is not fully understood, it is known to prevent the production of Bcr-Abl and Mcl-1, which help drive CML.
In October 2012, the FDA granted omacetaxine mepesuccinate accelerated approval for the treatment of adult patients with chronic or accelerated phase CML with resistance and/or intolerance to 2 or more tyrosine kinase inhibitors. Omacetaxine mepesuccinate gained full FDA approval in February.
The drug has been associated with severe and fatal myelosuppression, including thrombocytopenia, neutropenia, and anemia in some patients. So healthcare professionals should monitor patients’ complete blood counts weekly during induction and initial maintenance cycles and every 2 weeks during later maintenance cycles, as clinically indicated.
Omacetaxine mepesuccinate has been known to cause severe thrombocytopenia, which increases the risk of hemorrhage. Fatalities from cerebral hemorrhage have occurred. And severe, non-fatal gastrointestinal hemorrhages have occurred.
So healthcare professionals should monitor platelet counts as part of the complete blood count as recommended. Patients should not receive anticoagulants, aspirin, or non-steroidal anti-inflammatory drugs when their platelet counts are <50,000/μL, as these drugs may increase the risk of bleeding.
Omacetaxine mepesuccinate can induce glucose intolerance as well. So healthcare professionals should monitor blood glucose levels frequently, especially in patients with diabetes or risk factors for diabetes. Patients with poorly controlled diabetes mellitus should not receive omacetaxine mepesuccinate until good glycemic control has been established.
Omacetaxine mepesuccinate can cause fetal harm when administered to a pregnant woman. So women should be advised to avoid becoming pregnant while using the drug.
For more details on omacetaxine mepesuccinate, see the full prescribing information.
The US Food and Drug Administration (FDA) has expanded the approval of omacetaxine mepesuccinate (Synribo) to include home administration.
The drug is already FDA-approved to treat adults with chronic or accelerated phase chronic myeloid leukemia (CML) who do not respond to or cannot tolerate 2 or more tyrosine kinase inhibitors.
The new approval allows CML patients to self-administer subcutaneous injections of omacetaxine mepesuccinate at home.
“It had been necessary for adults living with chronic or accelerated phase CML who are prescribed Synribo to travel to their doctor’s office twice a day for 2 weeks, which can be extremely burdensome and inconvenient to both patients and their caregivers,” said Meir Wetzler, MD, FACP, Chief of the Leukemia Section at Roswell Park Cancer Institute in Buffalo, New York.
“Now, physicians can decide if their patients are candidates for self-administration and, if so, provide their patients with guidance on how to properly administer reconstituted Synribo in the home.”
The drug’s maker, Teva Pharmaceutical Industries, Ltd., is working to finalize a pharmacy support program that will help facilitate successful home administration of omacetaxine mepesuccinate. The program is expected to “go live” this month or next.
About omacetaxine mepesuccinate
Omacetaxine mepesuccinate is a protein synthesis inhibitor. Although the drug’s mechanism of action is not fully understood, it is known to prevent the production of Bcr-Abl and Mcl-1, which help drive CML.
In October 2012, the FDA granted omacetaxine mepesuccinate accelerated approval for the treatment of adult patients with chronic or accelerated phase CML with resistance and/or intolerance to 2 or more tyrosine kinase inhibitors. Omacetaxine mepesuccinate gained full FDA approval in February.
The drug has been associated with severe and fatal myelosuppression, including thrombocytopenia, neutropenia, and anemia in some patients. So healthcare professionals should monitor patients’ complete blood counts weekly during induction and initial maintenance cycles and every 2 weeks during later maintenance cycles, as clinically indicated.
Omacetaxine mepesuccinate has been known to cause severe thrombocytopenia, which increases the risk of hemorrhage. Fatalities from cerebral hemorrhage have occurred. And severe, non-fatal gastrointestinal hemorrhages have occurred.
So healthcare professionals should monitor platelet counts as part of the complete blood count as recommended. Patients should not receive anticoagulants, aspirin, or non-steroidal anti-inflammatory drugs when their platelet counts are <50,000/μL, as these drugs may increase the risk of bleeding.
Omacetaxine mepesuccinate can induce glucose intolerance as well. So healthcare professionals should monitor blood glucose levels frequently, especially in patients with diabetes or risk factors for diabetes. Patients with poorly controlled diabetes mellitus should not receive omacetaxine mepesuccinate until good glycemic control has been established.
Omacetaxine mepesuccinate can cause fetal harm when administered to a pregnant woman. So women should be advised to avoid becoming pregnant while using the drug.
For more details on omacetaxine mepesuccinate, see the full prescribing information.
Teaching Cases Perception vs Reality
The advent of work‐hour restrictions and admission limits for teaching services has led many academic hospitals to implement hospitalist‐run staff (ie, nonteaching) services.[1] Although this practice is not new,[2] it is growing in popularity[3] and has been endorsed as a way to protect resident teaching and prevent excessive workload.[4] One potential benefit is the assignment of more educational cases to teaching services, whereas the nonteaching services receive more patients whose care is presumably relatively mundane or routine.[5]
Despite the rapid growth of this system of educational triage,[6] little is known about the factors considered when teaching versus nonteaching decisions are made. Studies of clinical outcomes for patients assigned to teaching versus nonteaching services have understandably used random assignment,[7, 8] whereas a study finding that patients with unhealthy substance use were more likely to be on teaching services than nonteaching services relied on patient assignment based on the identity of the patient's primary care provider or insurer.[9] In 2009, O'Connor et al. reported that implementation of nonteaching services at 2 hospitals had led to unequal distribution of patients in terms of demographics, diagnosis, and illness severity.[10] Triage decisions were made by either a nurse coordinator or a medical chief resident, and sicker patients (and occasionally good teaching cases) were preferentially placed on the teaching services, reportedly out of respect for the comfort level of the midlevel providers who staffed the nonteaching services.
Our institution has used a system of hospitalist educational triage since 1998. Over that time, residents have often expressed concerns about the assignment of patients to the teaching services, reporting in particular that they receive a disproportionate number of complex cases and outside transfers. In 2006, the hospitalist group attempted to address these concerns by collecting real‐time admission data, but the application of the data was limited by suspicion on both sides of a Hawthorne effect (data not published).
If trainee and hospitalist expectations for what constitutes a great teaching case differ substantially, that difference can have significant implications for resident and medical student teaching, self‐perceived roles, and satisfaction. More significantly, an understanding of what faculty perceive as ideal teaching cases would provide valuable information about the strengths and weaknesses of the teachingnonteaching model, which may prove useful to other academic institutions considering such a system. In this study, we endeavored to understand what residents and hospitalists consider an educational admission and to compare these expectations to the actual triage decisions of hospitalists.
METHODS
Mayo Clinic Hospital (Phoenix, Arizona) has used separate teaching and nonteaching services since opening in 1998. At our institution, like many others,[11] a hospitalist is assigned to take all calls for emergency department (ED) admissions, admissions from outpatient clinics, and transfer requests; this physician directs patients to the teaching or nonteaching service. At the time of our study, the 2 teaching services alternated days in which they admitted up to 7 patients, and the 5 nonteaching services admitted all other patients and provided medicine consultative services for the hospital. Teaching services consisted of 1 hospitalist, 2 senior residents, 2 or 3 first‐year residents, and sometimes 1 third‐ or fourth‐year medical student. Nonteaching services consisted of a hospitalist with intermittent assistance from a physician assistant or nurse practitioner.
Although there are no formal guidelines for the hospitalist triage role, hospitalists are encouraged to assign more educational cases to the teaching services and to allow the residents enough time to address the acute needs of the prior admission before receiving the next admission. Residents are not assigned any patients between 4:00 am and 7:00 am. The goals and objectives for the resident rotation on the medicine teaching service include a list of diagnoses with which residents are expected to become familiar during their residency; triage hospitalists have on‐line access to these goals and objectives.
To assess resident and hospitalist opinions about what types of patients should or should not be admitted to teaching services and to compare those characteristics with those of the patients actually admitted to teaching services, we began by administering a simple, open‐ended survey and asked both groups: (1) In an ideal world, what kinds of patients should be admitted to the internal medicine teaching services at Mayo Clinic Hospital? (2) In the real world, what kinds of patients are admitted to the internal medicine teaching services at Mayo Clinic Hospital?
Ample space was provided for free‐text entries. Residents were additionally asked their postgraduate year level. The survey was administered in April 2011, at which time all residents would have rotated on the medicine teaching services several times. Survey responses were anonymous and were compiled and retyped by someone unfamiliar with the subjects' handwriting.
Two authors (D.L.R. and H.R.L.) reviewed the results of the first survey and used conventional content analysis to group responses into categories and tally them.[12] Responses from hospitalists and residents were used to determine the content for a second, quantitative survey that asked respondents to rate specific possible factors that affected triage decisions on a Likert scale from 1 (Argues against teaching admission) to 5 (Argues for teaching admission). The second survey, administered to the same residents and hospitalists in May 2011, asked: (1) In an ideal world, how do these factors contribute to the decision about which patients should be admitted to the internal medicine teaching services at Mayo Clinic Hospital? (2) In the real world, how do these factors contribute to the decision about which patients are admitted to the internal medicine teaching services at Mayo Clinic Hospital?
Assuming a 3:1 ratio of nonteaching to teaching admissions, we calculated that we would need to analyze 1028 admissions to detect a 10% difference in the proportion of a specific trait present in 50% of patients admitted to the nonteaching service, with the use of a 2‐sided test with 80% statistical power and a significance level of 0.05.
We collected data on patient assignment via retrospective chart review to avoid the possibility of a Hawthorne effect. We studied all admissions to the internal medicine services for a 3‐month period before the administration of the first survey (January 1, 2011 through March 31, 2011). The following patient data were collected: service assignment (teaching vs nonteaching), age, sex, source of admission (ED, direct from clinic, outside transfer, internal transfer from another hospital service), first visit to our institution, prior hematology or oncology visit at our institution (as a surrogate for cancer), prior psychiatry visit at our institution (as a surrogate for psychiatric disease), transplantation history, human immunodeficiency virus (HIV) or acquired immune deficiency syndrome (AIDS) history, chronic or functional pain mentioned in ED or admission note, need for translator, and benefactor status. Additionally, an online calculator was used to determine the Charlson Comorbidity Index score for each patient.[13] We collected actual patient data corresponding to factors reported by survey respondents whenever possible and practical, but not every factor reported by survey respondents was amenable to rigorous analysis; for example, no unbiased method could be devised to rigorously categorize patients whose admissions are likely to take more time or difficult patients and families.
Responses to the second (quantitative) survey and patient data were compared using the Pearson [2] and Fisher exact test for categorical variables and the Student t test or Wilcoxon rank sum test for continuous variables. Categorical variables that achieved statistical significance for overall difference were analyzed on a post hoc basis using the Bonferroni method to control for the overall type I error rate. We also examined the differences between actual and ideal triage decisions using the Wilcoxon signed rank test. Data were analyzed using SAS 9.3 (SAS Institute, Inc., Cary, NC). Statistical significance was defined as P<0.05.
The project was deemed exempt by the Mayo Clinic institutional review board.
RESULTS
We surveyed all categorical internal medicine residents (n=30, 10 each from postgraduate year [PGY]‐1, PGY‐2, and PGY‐3) and hospitalists except the authors (n=21; average years since completing training=13.3; range, 129 years). For both surveys, responses were collected from 29 (96.7%) residents. The nonresponding resident was a PGY‐2. The response rate for hospitalists was 20/21 (95.2%) for the first survey and 16/21 (76.2%) for the second survey.
First Survey
Table 1 compares the most frequent resident and faculty responses to the initial, open‐ended survey about what types of patients should or should not be admitted to teaching services. Residents most commonly indicated that ideal patients were traditional medicine cases (ie, bread‐and‐butter admissions, with 13 residents using that exact phrase), and others supplied specific examples of such cases, including chronic obstructive pulmonary disease, pneumonia, diabetic ketoacidosis, congestive heart failure, chest pain, and gastrointestinal tract bleeding. Only 1 faculty member mentioned bread‐and‐butter admissions, although several listed examples like chest pain and pneumonia. A smaller number of residents pointed to the importance of rare cases, whereas faculty considered rare cases to be ideal for teaching services, followed by variety of pathology and complexity.
Residents (n=29) | Faculty (n=20) | |||
---|---|---|---|---|
Question | Characteristic | No. (%) | Characteristic | No. (%) |
| ||||
In an ideal world, what kinds of patients should be admitted to the internal medicine teaching services at Mayo Clinic Hospital? | Bread‐and butter admissionsb | 14 (44.8) | Rare cases | 9 (45.0) |
Rare cases | 9 (31.0) | Variety of pathology | 7 (35.0) | |
No social admissions | 7 (24.1) | Complex cases | 5 (25.0) | |
New diagnoses instead of chronic management | 4 (13.8) | Variety of complexity | 5 (25.0) | |
Variety of complexity | 4 (13.8) | Patients with HIV/AIDS | 3 (15.0) | |
Diagnostic dilemmas | 3 (15.0) | |||
New diagnoses instead of chronic management | 3 (15.0) | |||
In the real world, what kinds of patients are admitted to the internal medicine teaching services at Mayo Clinic Hospital? | Patients with cancer | 11 (37.9) | Complex patients | 6 (30.0) |
Complex patients | 10 (34.5) | Difficult patients | 5 (25.0) | |
Social admissions | 9 (31.0) | Patients whose admissions are expected to be time consuming | 5 (25.0) | |
Acutely ill patients | 6 (20.7) | Rare cases | 3 (15.0) | |
Variety of pathology | 6 (20.7) | Cases determined by the time of day | 3 (15.0) |
With regard to actual admissions, residents and faculty agreed that they often were complex, but residents were more likely to suggest high rates of patients with cancer (11 residents vs 2 hospitalists) and social admissions (9 residents vs 2 hospitalists). Four residents each believed that they preferentially received elderly patients, outside transfers, and patients with functional pain, and 2 perceived a disproportionate number of patients making their first visit to Mayo Clinic. One hospitalist believed that residents were more likely to receive non‐English speakers.
Second Survey
Table 2 compares the resident and faculty responses to the second, numerical survey regarding ideal admissions to the teaching services. In contrast to the first survey, residents prioritized rare cases as the feature they most associated with ideal teaching admissions. They also placed a premium on variety of pathology, patients with unique findings, and patients likely to be written up or presented. The patients they believed were least appropriate for a teaching service were social admissions or those with placement issues, patients with functional or chronic pain, and benefactors or public figures.
Factor | Resident, n=29 | Faculty, n=16 | P Value |
---|---|---|---|
| |||
Rare diseases | 0.22 | ||
Mean (SD) | 4.8 (0.5) | 4.9 (0.3) | |
Median | 5 | 5 | |
Variety of pathology | 0.22 | ||
Mean (SD) | 4.7 (0.5) | 4.5 (0.5) | |
Median | 5 | 5 | |
Cases that might be written up or presented | 0.35 | ||
Mean (SD) | 4.7 (0.5) | 4.8 (0.6) | |
Median | 5 | 5 | |
Bread‐and‐butter cases | 0.001 | ||
Mean (SD) | 4.6 (0.7) | 3.7 (0.9) | |
Median | 5 | 4 | |
Unique physical findings | 0.67 | ||
Mean (SD) | 4.6 (0.6) | 4.7 (0.5) | |
Median | 5 | 5 | |
Variety of complexity | 0.21 | ||
Mean (SD) | 4.3 (0.7) | 4.1 (0.6) | |
Median | 4 | 4 | |
Variety of acuity | 0.40 | ||
Mean (SD) | 4.2 (0.7) | 4.1 (0.7) | |
Median | 4 | 4 | |
Spectrum of ages | 0.046 | ||
Mean (SD) | 4.1 (0.8) | 3.6 (0.8) | |
Median | 4 | 3 | |
HIV or AIDS | 0.39 | ||
Mean (SD) | 4.1 (0.9) | 4.4 (0.5) | |
Median | 4 | 4 | |
Acutely ill or unstable | 0.54 | ||
Mean (SD) | 4.0 (0.9) | 3.9 (0.6) | |
Median | 4 | 4 | |
Complex patients | 0.94 | ||
Mean (SD) | 4.0 (0.8) | 3.9 (0.6) | |
Median | 4 | 4 | |
Patients at end of life | 0.16 | ||
Mean (SD) | 3.5 (0.8) | 3.1 (0.6) | |
Median | 3 | 3 | |
First‐time Mayo patients | 0.45 | ||
Mean (SD) | 3.5 (0.7) | 3.3 (0.5) | |
Median | 3 | 3 | |
Younger patients | 0.50 | ||
Mean (SD) | 3.5 (0.9) | 3.3 (0.6) | |
Median | 3 | 3 | |
Stable patients | 0.21 | ||
Mean (SD) | 3.3 (0.8) | 3.1 (0.3) | |
Median | 3 | 3 | |
Patients with cancer | 0.67 | ||
Mean (SD) | 3.3 (0.8) | 3.1 (0.4) | |
Median | 3 | 3 | |
Straightforward patients | 0.64 | ||
Mean (SD) | 3.2 (0.8) | 3.1 (0.8) | |
Median | 3 | 3 | |
Older patients | 0.73 | ||
Mean (SD) | 3.2 (0.7) | 3.1 (0.3) | |
Median | 3 | 3 | |
Patients with a history of transplantation | 0.67 | ||
Mean (SD) | 3.1 (1.1) | 3.3 (0.6) | |
Median | 3 | 3 | |
Time of day of admission | 0.71 | ||
Mean (SD) | 3.1 (1.0) | 3.1 (0.5) | |
Median | 3 | 3 | |
Patients with a history of psychiatric illness | 0.59 | ||
Mean (SD) | 3.1 (1.0) | 3.1 (0.6) | |
Median | 3 | 3 | |
Patients who require a translator | 0.49 | ||
Mean (SD) | 3.0 (0.9) | 3.1 (0.5) | |
Median | 3 | 3 | |
Patients whose admissions are expected to take more time | 0.13 | ||
Mean (SD) | 2.9 (0.8) | 3.2 (0.6) | |
Median | 3 | 3 | |
Difficult patients and families | 0.55 | ||
Mean (SD) | 2.8 (1.0) | 2.6 (0.8) | |
Median | 3 | 3 | |
Transfers from other hospitals | 0.11 | ||
Mean (SD) | 2.7 (1.1) | 3.1 (0.3) | |
Median | 3 | 3 | |
Benefactors and public figures | 0.49 | ||
Mean (SD) | 2.7 (1.0) | 2.5 (0.7) | |
Median | 3 | 3 | |
Patients with functional or chronic pain | 0.87 | ||
Mean (SD) | 2.4 (1.1) | 2.4 (1.0) | |
Median | 2 | 3 | |
Social admissions or placement issues | 0.99 | ||
Mean (SD) | 2.1 (1.1) | 2.0 (1.0) | |
Median | 2 | 2 |
Faculty prioritized many of the same features for ideal teaching cases as residents; 4 of their 5 highest‐scoring factors were the same (rare diseases, patients whose cases might be written up or presented, patients with unique physical findings, and variety of pathology). They also agreed on the least ideal features (social admissions or placement issues, patients with functional or chronic pain, and benefactors or public figures). The only significant differences between resident and faculty ratings for ideal teaching cases were for bread‐and‐butter cases and a spectrum of ages.
Discordance between resident and faculty survey responses on actual admission decisions (Table 3) was starker; residents rated several features significantly higher than faculty as features contributing to triage decisions including older patients; patients with functional or chronic pain, social admissions, or placement issues; patients with cancer; transfers from other hospitals; and difficult patients and families. Relative to residents, faculty reported that patients with HIV or AIDS, and patients whose cases were likely to be written up or presented, were more likely to be admitted to teaching services.
Factor | Resident, n=29 | Faculty, n=16 | P Value |
---|---|---|---|
| |||
Rare diseases | 0.14 | ||
Mean (SD) | 4.4 (0.6) | 4.7 (0.6) | |
Median | 4 | 5 | |
Complex patients | 0.83 | ||
Mean (SD) | 4.3 (0.6) | 4.3 (0.6) | |
Median | 4 | 4 | |
Acutely ill or unstable | 0.18 | ||
Mean (SD) | 4.3 (0.7) | 3.9 (0.9) | |
Median | 4 | 4 | |
Unique physical findings | 0.18 | ||
Mean (SD) | 4.1 (0.8) | 4.5 (0.6) | |
Median | 4 | 5 | |
Transfers from other hospitals | 0.003 | ||
Mean (SD) | 4.1 (1.0) | 3.5 (0.5) | |
Median | 4 | 3 | |
Cases that might be written up or presented | 0.03 | ||
Mean (SD) | 4.1 (0.7) | 4.6 (0.6) | |
Median | 4 | 5 | |
Older patients | <0.001 | ||
Mean (SD) | 3.9 (0.8) | 3.0 (0.7) | |
Median | 4 | 3 | |
Time of day of admission | 0.50 | ||
Mean (SD) | 3.9 (1.1) | 3.7 (0.9) | |
Median | 4 | 4 | |
Patients with cancer | 0.01 | ||
Mean (SD) | 3.9 (0.9) | 3.3 (0.5) | |
Median | 4 | 3 | |
Variety of pathology | 0.21 | ||
Mean (SD) | 3.9 (0.8) | 4.2 (0.7) | |
Median | 4 | 4 | |
Patients whose admissions are expected to take more time | 0.13 | ||
Mean (SD) | 3.9 (1.0) | 3.4 (0.9) | |
Median | 4 | 3 | |
HIV or AIDS | 0.008 | ||
Mean (SD) | 3.8 (0.9) | 4.5 (0.5) | |
Median | 4 | 4.5 | |
Variety of complexity | 0.31 | ||
Mean (SD) | 3.7 (0.9) | 3.9 (0.6) | |
Median | 3.5 | 4 | |
Bread‐and‐butter cases | 0.07 | ||
Mean (SD) | 3.6 (1.0) | 2.9 (1.2) | |
Median | 3 | 3 | |
First‐time Mayo patients | 0.82 | ||
Mean (SD) | 3.6 (0.9) | 3.5 (0.7) | |
Median | 3 | 3 | |
Patients with functional or chronic pain | 0.004 | ||
Mean (SD) | 3.6 (1.0) | 2.8 (0.7) | |
Median | 4 | 3 | |
Social admissions or placement issues | 0.03 | ||
Mean (SD) | 3.5 (1.2) | 2.7 (0.9) | |
Median | 4 | 3 | |
Variety of acuity | 0.25 | ||
Mean (SD) | 3.5 (0.8) | 3.7 (0.6) | |
Median | 3 | 4 | |
Difficult patients and families | 0.03 | ||
Mean (SD) | 3.4 (0.9) | 2.8 (0.7) | |
Median | 3 | 3 | |
Patients at end of life | 0.10 | ||
Mean (SD) | 3.4 (0.8) | 3.0 (0.5) | |
Median | 3 | 3 | |
Spectrum of ages | 0.80 | ||
Mean (SD) | 3.3 (0.7) | 3.3 (0.6) | |
Median | 3 | 3 | |
Patients with a history of psychiatric illness | 0.81 | ||
Mean (SD) | 3.3 (0.9) | 3.1 (0.6) | |
Median | 3 | 3 | |
Patients with a history of transplantation | 0.25 | ||
Mean (SD) | 3.2 (0.9) | 3.5 (0.5) | |
Median | 3 | 3 | |
Patients who require a translator | 0.60 | ||
Mean (SD) | 3.2 (0.7) | 3.2 (0.6) | |
Median | 3 | 3 | |
Younger patients | 0.42 | ||
Mean (SD) | 3.0 (0.9) | 3.1 (0.4) | |
Median | 3 | 3 | |
Benefactors and public figures | 0.09 | ||
Mean (SD) | 2.9 (1.0) | 2.3 (0.7) | |
Median | 3 | 2 | |
Straightforward patients | 0.18 | ||
Mean (SD) | 2.8 (1.0) | 2.4 (1.0) | |
Median | 2.5 | 2 | |
Stable patients | 0.53 | ||
Mean (SD) | 2.7 (1.0) | 2.8 (0.7) | |
Median | 3 | 3 |
Comparing resident survey ratings for ideal versus actual triage decisions gave some insight into the features that they thought were inappropriately emphasized or ignored when triage decisions were made. Differences in resident scores for ideal versus actual admissions were significantly different for 16 of 28 items (data available upon request), suggesting a degree of perceived discordance. The largest positive differences (ie, features they valued in teaching admissions but thought were less represented in actual admissions) were for bread‐and‐butter admissions, variety of pathology, a spectrum of ages, and variety of acuity. The largest negative differences (ie, features they thought were well represented in actual admissions but were less valuable) were for social admissions or placement issues, transfers from other hospitals, patients with functional or chronic pain, and patients whose admissions were expected to take more time.
In terms of ideal versus actual triage decisions, faculty reported less discordance than residents; ideal and actual triage behavior differed significantly only for 4 of 28 items (data available upon request). They did agree with residents about the relative lack of bread‐and‐butter admissions and the over‐representation of social admissions or placement issues and transfers from other hospitals. They additionally noted a lack of straightforward cases.
We reviewed records of the 1426 patients admitted to the internal medicine services during the study period. Of these, 359 (25.2%) were assigned to the teaching services. Patient characteristics are summarized in Table 4.
Characteristic | Teaching Service, n=359 | Nonteaching Service, n=1,067 | P Value |
---|---|---|---|
| |||
Age, y, mean (SD) | 66.7 (16.5) | 69.3 (15.7) | 0.008 |
Admission type, No. (%) | 0.049 | ||
Admission from the emergency department | 315 (87.7) | 915 (85.8) | 0.34 |
Direct admission from Mayo outpatient clinic | 27 (7.5) | 114 (10.7) | 0.08 |
Transfer from another institution | 16 (4.5) | 27 (2.5) | 0.06 |
Internal transfer from a different hospital service | 1 (0.3) | 11 (1.0) | 0.31 |
First‐time Mayo patient, No. (%) | 61 (17.0) | 175 (16.4) | 0.79 |
Prior hematology or oncology visit, No. (%) | 86 (24.0) | 235 (22.0) | 0.45 |
History of transplantation, No. (%) | 20 (5.6) | 52 (4.9) | 0.60 |
Prior psychiatry visit, No. (%) | 53 (14.8) | 122 (11.4) | 0.10 |
History of chronic or functional pain, No. (%) | 122 (34.0) | 330 (30.9) | 0.28 |
Required translator, No. (%) | 5 (1.4) | 14 (1.3) | 0.91 |
Benefactor, No. (%) | 5 (1.4) | 24 (2.2) | 0.32 |
Charlson comorbidity score, mean (SD) | 2.7 (2.5) | 2.6 (2.5) | 0.49 |
DISCUSSION
The results of our qualitative and quantitative surveys showed significant differences between resident and staff perceptions of the faculty triage role. Although both groups similarly valued many features, residents expressed a clear preference for more bread‐and‐butter admissions, whereas the staff prioritized selecting the most complex, challenging, and rare cases from among the day's admissions to give to the residents. (Residents were also very interested in rare cases, suggesting that they saw benefit to admitting patients with a variety of degrees of rarity and complexity.) Residents and faculty seemed to agree that the number of social admissions and outside transfers admitted to teaching services was not ideal.
These perceptions have substantial implications. If the current triage process is to continue, there may be benefit to designing a faculty development project focused on the triage process, which previously has been largely unexamined. Efforts to remove or limit time barriers that prevent perceived educational cases from being admitted to teaching services is also a worthy endeavor (eg, structuring the 2 teams to admit simultaneously so that teaching teams can admit patients back to back without exceeding capacity). In addition, residents may benefit from teaching hospitalists who concentrate educational efforts on the learning that can be extracted from the care of any patient, including admissions that initially seem mundane or purely social.[14] A concerted effort to divert more traditional medicine admissions and fewer unusual cases to the teaching service might improve resident perceptions of the triage process. Further, although the care of any patient can have education benefit, the fact that both groups perceived excessive social admissions in the teaching service suggests that a potential benefit of a nonteaching service (ie, absorbing the most mundane admissions) may not yet be fully realized.
Despite the perceived differences noted on the surveys, we found remarkably few differences between patients admitted to the teaching and nonteaching services. Although both groups rated complexity; outside transfers; being seen at the institution for the first time; and histories of transplantation, cancer, chronic or functional pain, and psychiatric disease as increasing the likelihood of admission to a teaching service, no differences were observed for these factors or their quantifiable surrogates. (Although the overall test for admission type achieved marginal statistical significance, none of the individual admission types were significantly different in post hoc analysis.) Residents, but not faculty, thought that older patients were over‐represented on the teaching service, but their assigned patients were significantly younger than those on the nonteaching service.
These findings have several possible explanations. First, although most hospitalists spend time on teaching and nonteaching services (and therefore are familiar with the patient composition of each), residents get very little exposure to the nonteaching services (until they are senior residents with a rotation on a consulting service). Their impression of inequity may be due to misunderstanding the patient composition of the nonteaching services. Second, the mere existence of a triage role may create false expectations about patient composition; that is, simply by knowing that every admission was chosen for its educational merit, residents may have disproportionate perceptions about those cases judged to have less educational value, even ifas our data suggestassignments to teaching versus nonteaching services are occurring fairly equitably.
Study Limitations
We acknowledge several limitations of our study. First, many factors that were reported as important in the qualitative survey did not lend themselves to objective abstraction from patient records. For example, providers did not specifically document when an admission is purely social, nor was there an objective way to identify difficult patients or families or admissions that were expected to take more time. We attempted to limit the analysis to objective patient metrics that were (1) not influenced by the teaching or nonteaching assignment itself (eg, we avoided discharge diagnoses, which might be entered differently by residents and staff hospitalists) and (2) easily available to triage hospitalists. For the latter reason, we used a prior appointment in the hematology or oncology clinic as a surrogate for cancer patients and a prior psychiatry visit as a surrogate for patients with a history of psychiatric disease. These are naturally inexact surrogates, but they reflect the information a busy hospitalist is likely to access when making patient assignment decisions.
Second, it may well be that assigning patients equitably according to a certain trait is not the same as assigning patients ideally for the educational needs of residents. The patients admitted to our medicine services (teaching and nonteaching) were generally older than 60 years, had complex diagnoses, and had substantial pain. Residents on the teaching services potentially would benefit from an intentionally unbalanced admission policy that shunted patients to the teaching services on the basis of features other than individual perceived educational merit. It must also be borne in mind that resident, and for that matter faculty, perceptions of ideal teaching cases are likely inexact correlates of educational best practices; the ideal role of the triage hospitalist is to admit to the teaching services those patients that will best advance the education of the learners, including a consideration of the goals and objectives of the rotation. Future studies correlating different triage practices to actual educational outcomes would be very helpful.
Third, the analysis could not reliably eliminate patients whose admissions did not represent genuine triage decisions (eg, those assigned to the hospitalist service after the teaching service had reached its capacity or immediately after they had received a complex case). Studying admission decisions prospectively could eliminate this variability, but it could introduce a Hawthorne effect, the negative effects of which likely would outweigh this benefit.
CONCLUSION
Triage hospitalists distributed patients fairly evenly between teaching and nonteaching services, but residents and faculty alike perceived that residents would benefit from more bread‐and‐butter cases. Hospitals considering the addition of a nonteaching service may want to incorporate a faculty development project focused on the triage process to ensure that these traditional medicine cases are assigned to resident services and to ensure that the great teaching case is not considered such because of complexity and acuity alone.
Acknowledgements
The authors thank Elizabeth Jones and Lois Bell for their assistance with survey collection and collation.
Disclosures: This study (institutional review board application #11‐3;002635) was deemed exempt by the Mayo Clinic institutional review board on May 16, 2011. The authors report no conflicts of interest.
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- A randomized, controlled trial of an attending staff service in general internal medicine. Med Care. 1991;29(7 suppl):JS31–JS40. , , , , .
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- Education Committee of the American College of Physicians. Redesigning training for internal medicine. Ann Intern Med. 2006;144(12):927–932. , , ;
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- Hospitalists and an innovative emergency department admission process. J Gen Intern Med. 2004;19(3):266–268. , , .
- Comparison of resource utilization and clinical outcomes between teaching and nonteaching medical services. J Hosp Med. 2007;2(3):150–157. , , , , .
- A comparative study of unscheduled hospital readmissions in a resident‐staffed teaching service and a hospitalist‐based service. South Med J. 2009;102(2):145–149. , , , .
- Prevalence of unhealthy substance use on teaching and hospitalist medical services: implications for education. Am J Addict. 2012;21(2):111–119. , , , et al.
- The effect of nonteaching services on the distribution of inpatient cases for internal medicine residents. Acad Med. 2009;84(2):220–225. , , , et al.
- http://www.todayshospita list.com/index.php?b=articles_read15(9):1277–1288. Teaching and nonteaching services: separate no more? Today's Hospitalist website. Available at:
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The advent of work‐hour restrictions and admission limits for teaching services has led many academic hospitals to implement hospitalist‐run staff (ie, nonteaching) services.[1] Although this practice is not new,[2] it is growing in popularity[3] and has been endorsed as a way to protect resident teaching and prevent excessive workload.[4] One potential benefit is the assignment of more educational cases to teaching services, whereas the nonteaching services receive more patients whose care is presumably relatively mundane or routine.[5]
Despite the rapid growth of this system of educational triage,[6] little is known about the factors considered when teaching versus nonteaching decisions are made. Studies of clinical outcomes for patients assigned to teaching versus nonteaching services have understandably used random assignment,[7, 8] whereas a study finding that patients with unhealthy substance use were more likely to be on teaching services than nonteaching services relied on patient assignment based on the identity of the patient's primary care provider or insurer.[9] In 2009, O'Connor et al. reported that implementation of nonteaching services at 2 hospitals had led to unequal distribution of patients in terms of demographics, diagnosis, and illness severity.[10] Triage decisions were made by either a nurse coordinator or a medical chief resident, and sicker patients (and occasionally good teaching cases) were preferentially placed on the teaching services, reportedly out of respect for the comfort level of the midlevel providers who staffed the nonteaching services.
Our institution has used a system of hospitalist educational triage since 1998. Over that time, residents have often expressed concerns about the assignment of patients to the teaching services, reporting in particular that they receive a disproportionate number of complex cases and outside transfers. In 2006, the hospitalist group attempted to address these concerns by collecting real‐time admission data, but the application of the data was limited by suspicion on both sides of a Hawthorne effect (data not published).
If trainee and hospitalist expectations for what constitutes a great teaching case differ substantially, that difference can have significant implications for resident and medical student teaching, self‐perceived roles, and satisfaction. More significantly, an understanding of what faculty perceive as ideal teaching cases would provide valuable information about the strengths and weaknesses of the teachingnonteaching model, which may prove useful to other academic institutions considering such a system. In this study, we endeavored to understand what residents and hospitalists consider an educational admission and to compare these expectations to the actual triage decisions of hospitalists.
METHODS
Mayo Clinic Hospital (Phoenix, Arizona) has used separate teaching and nonteaching services since opening in 1998. At our institution, like many others,[11] a hospitalist is assigned to take all calls for emergency department (ED) admissions, admissions from outpatient clinics, and transfer requests; this physician directs patients to the teaching or nonteaching service. At the time of our study, the 2 teaching services alternated days in which they admitted up to 7 patients, and the 5 nonteaching services admitted all other patients and provided medicine consultative services for the hospital. Teaching services consisted of 1 hospitalist, 2 senior residents, 2 or 3 first‐year residents, and sometimes 1 third‐ or fourth‐year medical student. Nonteaching services consisted of a hospitalist with intermittent assistance from a physician assistant or nurse practitioner.
Although there are no formal guidelines for the hospitalist triage role, hospitalists are encouraged to assign more educational cases to the teaching services and to allow the residents enough time to address the acute needs of the prior admission before receiving the next admission. Residents are not assigned any patients between 4:00 am and 7:00 am. The goals and objectives for the resident rotation on the medicine teaching service include a list of diagnoses with which residents are expected to become familiar during their residency; triage hospitalists have on‐line access to these goals and objectives.
To assess resident and hospitalist opinions about what types of patients should or should not be admitted to teaching services and to compare those characteristics with those of the patients actually admitted to teaching services, we began by administering a simple, open‐ended survey and asked both groups: (1) In an ideal world, what kinds of patients should be admitted to the internal medicine teaching services at Mayo Clinic Hospital? (2) In the real world, what kinds of patients are admitted to the internal medicine teaching services at Mayo Clinic Hospital?
Ample space was provided for free‐text entries. Residents were additionally asked their postgraduate year level. The survey was administered in April 2011, at which time all residents would have rotated on the medicine teaching services several times. Survey responses were anonymous and were compiled and retyped by someone unfamiliar with the subjects' handwriting.
Two authors (D.L.R. and H.R.L.) reviewed the results of the first survey and used conventional content analysis to group responses into categories and tally them.[12] Responses from hospitalists and residents were used to determine the content for a second, quantitative survey that asked respondents to rate specific possible factors that affected triage decisions on a Likert scale from 1 (Argues against teaching admission) to 5 (Argues for teaching admission). The second survey, administered to the same residents and hospitalists in May 2011, asked: (1) In an ideal world, how do these factors contribute to the decision about which patients should be admitted to the internal medicine teaching services at Mayo Clinic Hospital? (2) In the real world, how do these factors contribute to the decision about which patients are admitted to the internal medicine teaching services at Mayo Clinic Hospital?
Assuming a 3:1 ratio of nonteaching to teaching admissions, we calculated that we would need to analyze 1028 admissions to detect a 10% difference in the proportion of a specific trait present in 50% of patients admitted to the nonteaching service, with the use of a 2‐sided test with 80% statistical power and a significance level of 0.05.
We collected data on patient assignment via retrospective chart review to avoid the possibility of a Hawthorne effect. We studied all admissions to the internal medicine services for a 3‐month period before the administration of the first survey (January 1, 2011 through March 31, 2011). The following patient data were collected: service assignment (teaching vs nonteaching), age, sex, source of admission (ED, direct from clinic, outside transfer, internal transfer from another hospital service), first visit to our institution, prior hematology or oncology visit at our institution (as a surrogate for cancer), prior psychiatry visit at our institution (as a surrogate for psychiatric disease), transplantation history, human immunodeficiency virus (HIV) or acquired immune deficiency syndrome (AIDS) history, chronic or functional pain mentioned in ED or admission note, need for translator, and benefactor status. Additionally, an online calculator was used to determine the Charlson Comorbidity Index score for each patient.[13] We collected actual patient data corresponding to factors reported by survey respondents whenever possible and practical, but not every factor reported by survey respondents was amenable to rigorous analysis; for example, no unbiased method could be devised to rigorously categorize patients whose admissions are likely to take more time or difficult patients and families.
Responses to the second (quantitative) survey and patient data were compared using the Pearson [2] and Fisher exact test for categorical variables and the Student t test or Wilcoxon rank sum test for continuous variables. Categorical variables that achieved statistical significance for overall difference were analyzed on a post hoc basis using the Bonferroni method to control for the overall type I error rate. We also examined the differences between actual and ideal triage decisions using the Wilcoxon signed rank test. Data were analyzed using SAS 9.3 (SAS Institute, Inc., Cary, NC). Statistical significance was defined as P<0.05.
The project was deemed exempt by the Mayo Clinic institutional review board.
RESULTS
We surveyed all categorical internal medicine residents (n=30, 10 each from postgraduate year [PGY]‐1, PGY‐2, and PGY‐3) and hospitalists except the authors (n=21; average years since completing training=13.3; range, 129 years). For both surveys, responses were collected from 29 (96.7%) residents. The nonresponding resident was a PGY‐2. The response rate for hospitalists was 20/21 (95.2%) for the first survey and 16/21 (76.2%) for the second survey.
First Survey
Table 1 compares the most frequent resident and faculty responses to the initial, open‐ended survey about what types of patients should or should not be admitted to teaching services. Residents most commonly indicated that ideal patients were traditional medicine cases (ie, bread‐and‐butter admissions, with 13 residents using that exact phrase), and others supplied specific examples of such cases, including chronic obstructive pulmonary disease, pneumonia, diabetic ketoacidosis, congestive heart failure, chest pain, and gastrointestinal tract bleeding. Only 1 faculty member mentioned bread‐and‐butter admissions, although several listed examples like chest pain and pneumonia. A smaller number of residents pointed to the importance of rare cases, whereas faculty considered rare cases to be ideal for teaching services, followed by variety of pathology and complexity.
Residents (n=29) | Faculty (n=20) | |||
---|---|---|---|---|
Question | Characteristic | No. (%) | Characteristic | No. (%) |
| ||||
In an ideal world, what kinds of patients should be admitted to the internal medicine teaching services at Mayo Clinic Hospital? | Bread‐and butter admissionsb | 14 (44.8) | Rare cases | 9 (45.0) |
Rare cases | 9 (31.0) | Variety of pathology | 7 (35.0) | |
No social admissions | 7 (24.1) | Complex cases | 5 (25.0) | |
New diagnoses instead of chronic management | 4 (13.8) | Variety of complexity | 5 (25.0) | |
Variety of complexity | 4 (13.8) | Patients with HIV/AIDS | 3 (15.0) | |
Diagnostic dilemmas | 3 (15.0) | |||
New diagnoses instead of chronic management | 3 (15.0) | |||
In the real world, what kinds of patients are admitted to the internal medicine teaching services at Mayo Clinic Hospital? | Patients with cancer | 11 (37.9) | Complex patients | 6 (30.0) |
Complex patients | 10 (34.5) | Difficult patients | 5 (25.0) | |
Social admissions | 9 (31.0) | Patients whose admissions are expected to be time consuming | 5 (25.0) | |
Acutely ill patients | 6 (20.7) | Rare cases | 3 (15.0) | |
Variety of pathology | 6 (20.7) | Cases determined by the time of day | 3 (15.0) |
With regard to actual admissions, residents and faculty agreed that they often were complex, but residents were more likely to suggest high rates of patients with cancer (11 residents vs 2 hospitalists) and social admissions (9 residents vs 2 hospitalists). Four residents each believed that they preferentially received elderly patients, outside transfers, and patients with functional pain, and 2 perceived a disproportionate number of patients making their first visit to Mayo Clinic. One hospitalist believed that residents were more likely to receive non‐English speakers.
Second Survey
Table 2 compares the resident and faculty responses to the second, numerical survey regarding ideal admissions to the teaching services. In contrast to the first survey, residents prioritized rare cases as the feature they most associated with ideal teaching admissions. They also placed a premium on variety of pathology, patients with unique findings, and patients likely to be written up or presented. The patients they believed were least appropriate for a teaching service were social admissions or those with placement issues, patients with functional or chronic pain, and benefactors or public figures.
Factor | Resident, n=29 | Faculty, n=16 | P Value |
---|---|---|---|
| |||
Rare diseases | 0.22 | ||
Mean (SD) | 4.8 (0.5) | 4.9 (0.3) | |
Median | 5 | 5 | |
Variety of pathology | 0.22 | ||
Mean (SD) | 4.7 (0.5) | 4.5 (0.5) | |
Median | 5 | 5 | |
Cases that might be written up or presented | 0.35 | ||
Mean (SD) | 4.7 (0.5) | 4.8 (0.6) | |
Median | 5 | 5 | |
Bread‐and‐butter cases | 0.001 | ||
Mean (SD) | 4.6 (0.7) | 3.7 (0.9) | |
Median | 5 | 4 | |
Unique physical findings | 0.67 | ||
Mean (SD) | 4.6 (0.6) | 4.7 (0.5) | |
Median | 5 | 5 | |
Variety of complexity | 0.21 | ||
Mean (SD) | 4.3 (0.7) | 4.1 (0.6) | |
Median | 4 | 4 | |
Variety of acuity | 0.40 | ||
Mean (SD) | 4.2 (0.7) | 4.1 (0.7) | |
Median | 4 | 4 | |
Spectrum of ages | 0.046 | ||
Mean (SD) | 4.1 (0.8) | 3.6 (0.8) | |
Median | 4 | 3 | |
HIV or AIDS | 0.39 | ||
Mean (SD) | 4.1 (0.9) | 4.4 (0.5) | |
Median | 4 | 4 | |
Acutely ill or unstable | 0.54 | ||
Mean (SD) | 4.0 (0.9) | 3.9 (0.6) | |
Median | 4 | 4 | |
Complex patients | 0.94 | ||
Mean (SD) | 4.0 (0.8) | 3.9 (0.6) | |
Median | 4 | 4 | |
Patients at end of life | 0.16 | ||
Mean (SD) | 3.5 (0.8) | 3.1 (0.6) | |
Median | 3 | 3 | |
First‐time Mayo patients | 0.45 | ||
Mean (SD) | 3.5 (0.7) | 3.3 (0.5) | |
Median | 3 | 3 | |
Younger patients | 0.50 | ||
Mean (SD) | 3.5 (0.9) | 3.3 (0.6) | |
Median | 3 | 3 | |
Stable patients | 0.21 | ||
Mean (SD) | 3.3 (0.8) | 3.1 (0.3) | |
Median | 3 | 3 | |
Patients with cancer | 0.67 | ||
Mean (SD) | 3.3 (0.8) | 3.1 (0.4) | |
Median | 3 | 3 | |
Straightforward patients | 0.64 | ||
Mean (SD) | 3.2 (0.8) | 3.1 (0.8) | |
Median | 3 | 3 | |
Older patients | 0.73 | ||
Mean (SD) | 3.2 (0.7) | 3.1 (0.3) | |
Median | 3 | 3 | |
Patients with a history of transplantation | 0.67 | ||
Mean (SD) | 3.1 (1.1) | 3.3 (0.6) | |
Median | 3 | 3 | |
Time of day of admission | 0.71 | ||
Mean (SD) | 3.1 (1.0) | 3.1 (0.5) | |
Median | 3 | 3 | |
Patients with a history of psychiatric illness | 0.59 | ||
Mean (SD) | 3.1 (1.0) | 3.1 (0.6) | |
Median | 3 | 3 | |
Patients who require a translator | 0.49 | ||
Mean (SD) | 3.0 (0.9) | 3.1 (0.5) | |
Median | 3 | 3 | |
Patients whose admissions are expected to take more time | 0.13 | ||
Mean (SD) | 2.9 (0.8) | 3.2 (0.6) | |
Median | 3 | 3 | |
Difficult patients and families | 0.55 | ||
Mean (SD) | 2.8 (1.0) | 2.6 (0.8) | |
Median | 3 | 3 | |
Transfers from other hospitals | 0.11 | ||
Mean (SD) | 2.7 (1.1) | 3.1 (0.3) | |
Median | 3 | 3 | |
Benefactors and public figures | 0.49 | ||
Mean (SD) | 2.7 (1.0) | 2.5 (0.7) | |
Median | 3 | 3 | |
Patients with functional or chronic pain | 0.87 | ||
Mean (SD) | 2.4 (1.1) | 2.4 (1.0) | |
Median | 2 | 3 | |
Social admissions or placement issues | 0.99 | ||
Mean (SD) | 2.1 (1.1) | 2.0 (1.0) | |
Median | 2 | 2 |
Faculty prioritized many of the same features for ideal teaching cases as residents; 4 of their 5 highest‐scoring factors were the same (rare diseases, patients whose cases might be written up or presented, patients with unique physical findings, and variety of pathology). They also agreed on the least ideal features (social admissions or placement issues, patients with functional or chronic pain, and benefactors or public figures). The only significant differences between resident and faculty ratings for ideal teaching cases were for bread‐and‐butter cases and a spectrum of ages.
Discordance between resident and faculty survey responses on actual admission decisions (Table 3) was starker; residents rated several features significantly higher than faculty as features contributing to triage decisions including older patients; patients with functional or chronic pain, social admissions, or placement issues; patients with cancer; transfers from other hospitals; and difficult patients and families. Relative to residents, faculty reported that patients with HIV or AIDS, and patients whose cases were likely to be written up or presented, were more likely to be admitted to teaching services.
Factor | Resident, n=29 | Faculty, n=16 | P Value |
---|---|---|---|
| |||
Rare diseases | 0.14 | ||
Mean (SD) | 4.4 (0.6) | 4.7 (0.6) | |
Median | 4 | 5 | |
Complex patients | 0.83 | ||
Mean (SD) | 4.3 (0.6) | 4.3 (0.6) | |
Median | 4 | 4 | |
Acutely ill or unstable | 0.18 | ||
Mean (SD) | 4.3 (0.7) | 3.9 (0.9) | |
Median | 4 | 4 | |
Unique physical findings | 0.18 | ||
Mean (SD) | 4.1 (0.8) | 4.5 (0.6) | |
Median | 4 | 5 | |
Transfers from other hospitals | 0.003 | ||
Mean (SD) | 4.1 (1.0) | 3.5 (0.5) | |
Median | 4 | 3 | |
Cases that might be written up or presented | 0.03 | ||
Mean (SD) | 4.1 (0.7) | 4.6 (0.6) | |
Median | 4 | 5 | |
Older patients | <0.001 | ||
Mean (SD) | 3.9 (0.8) | 3.0 (0.7) | |
Median | 4 | 3 | |
Time of day of admission | 0.50 | ||
Mean (SD) | 3.9 (1.1) | 3.7 (0.9) | |
Median | 4 | 4 | |
Patients with cancer | 0.01 | ||
Mean (SD) | 3.9 (0.9) | 3.3 (0.5) | |
Median | 4 | 3 | |
Variety of pathology | 0.21 | ||
Mean (SD) | 3.9 (0.8) | 4.2 (0.7) | |
Median | 4 | 4 | |
Patients whose admissions are expected to take more time | 0.13 | ||
Mean (SD) | 3.9 (1.0) | 3.4 (0.9) | |
Median | 4 | 3 | |
HIV or AIDS | 0.008 | ||
Mean (SD) | 3.8 (0.9) | 4.5 (0.5) | |
Median | 4 | 4.5 | |
Variety of complexity | 0.31 | ||
Mean (SD) | 3.7 (0.9) | 3.9 (0.6) | |
Median | 3.5 | 4 | |
Bread‐and‐butter cases | 0.07 | ||
Mean (SD) | 3.6 (1.0) | 2.9 (1.2) | |
Median | 3 | 3 | |
First‐time Mayo patients | 0.82 | ||
Mean (SD) | 3.6 (0.9) | 3.5 (0.7) | |
Median | 3 | 3 | |
Patients with functional or chronic pain | 0.004 | ||
Mean (SD) | 3.6 (1.0) | 2.8 (0.7) | |
Median | 4 | 3 | |
Social admissions or placement issues | 0.03 | ||
Mean (SD) | 3.5 (1.2) | 2.7 (0.9) | |
Median | 4 | 3 | |
Variety of acuity | 0.25 | ||
Mean (SD) | 3.5 (0.8) | 3.7 (0.6) | |
Median | 3 | 4 | |
Difficult patients and families | 0.03 | ||
Mean (SD) | 3.4 (0.9) | 2.8 (0.7) | |
Median | 3 | 3 | |
Patients at end of life | 0.10 | ||
Mean (SD) | 3.4 (0.8) | 3.0 (0.5) | |
Median | 3 | 3 | |
Spectrum of ages | 0.80 | ||
Mean (SD) | 3.3 (0.7) | 3.3 (0.6) | |
Median | 3 | 3 | |
Patients with a history of psychiatric illness | 0.81 | ||
Mean (SD) | 3.3 (0.9) | 3.1 (0.6) | |
Median | 3 | 3 | |
Patients with a history of transplantation | 0.25 | ||
Mean (SD) | 3.2 (0.9) | 3.5 (0.5) | |
Median | 3 | 3 | |
Patients who require a translator | 0.60 | ||
Mean (SD) | 3.2 (0.7) | 3.2 (0.6) | |
Median | 3 | 3 | |
Younger patients | 0.42 | ||
Mean (SD) | 3.0 (0.9) | 3.1 (0.4) | |
Median | 3 | 3 | |
Benefactors and public figures | 0.09 | ||
Mean (SD) | 2.9 (1.0) | 2.3 (0.7) | |
Median | 3 | 2 | |
Straightforward patients | 0.18 | ||
Mean (SD) | 2.8 (1.0) | 2.4 (1.0) | |
Median | 2.5 | 2 | |
Stable patients | 0.53 | ||
Mean (SD) | 2.7 (1.0) | 2.8 (0.7) | |
Median | 3 | 3 |
Comparing resident survey ratings for ideal versus actual triage decisions gave some insight into the features that they thought were inappropriately emphasized or ignored when triage decisions were made. Differences in resident scores for ideal versus actual admissions were significantly different for 16 of 28 items (data available upon request), suggesting a degree of perceived discordance. The largest positive differences (ie, features they valued in teaching admissions but thought were less represented in actual admissions) were for bread‐and‐butter admissions, variety of pathology, a spectrum of ages, and variety of acuity. The largest negative differences (ie, features they thought were well represented in actual admissions but were less valuable) were for social admissions or placement issues, transfers from other hospitals, patients with functional or chronic pain, and patients whose admissions were expected to take more time.
In terms of ideal versus actual triage decisions, faculty reported less discordance than residents; ideal and actual triage behavior differed significantly only for 4 of 28 items (data available upon request). They did agree with residents about the relative lack of bread‐and‐butter admissions and the over‐representation of social admissions or placement issues and transfers from other hospitals. They additionally noted a lack of straightforward cases.
We reviewed records of the 1426 patients admitted to the internal medicine services during the study period. Of these, 359 (25.2%) were assigned to the teaching services. Patient characteristics are summarized in Table 4.
Characteristic | Teaching Service, n=359 | Nonteaching Service, n=1,067 | P Value |
---|---|---|---|
| |||
Age, y, mean (SD) | 66.7 (16.5) | 69.3 (15.7) | 0.008 |
Admission type, No. (%) | 0.049 | ||
Admission from the emergency department | 315 (87.7) | 915 (85.8) | 0.34 |
Direct admission from Mayo outpatient clinic | 27 (7.5) | 114 (10.7) | 0.08 |
Transfer from another institution | 16 (4.5) | 27 (2.5) | 0.06 |
Internal transfer from a different hospital service | 1 (0.3) | 11 (1.0) | 0.31 |
First‐time Mayo patient, No. (%) | 61 (17.0) | 175 (16.4) | 0.79 |
Prior hematology or oncology visit, No. (%) | 86 (24.0) | 235 (22.0) | 0.45 |
History of transplantation, No. (%) | 20 (5.6) | 52 (4.9) | 0.60 |
Prior psychiatry visit, No. (%) | 53 (14.8) | 122 (11.4) | 0.10 |
History of chronic or functional pain, No. (%) | 122 (34.0) | 330 (30.9) | 0.28 |
Required translator, No. (%) | 5 (1.4) | 14 (1.3) | 0.91 |
Benefactor, No. (%) | 5 (1.4) | 24 (2.2) | 0.32 |
Charlson comorbidity score, mean (SD) | 2.7 (2.5) | 2.6 (2.5) | 0.49 |
DISCUSSION
The results of our qualitative and quantitative surveys showed significant differences between resident and staff perceptions of the faculty triage role. Although both groups similarly valued many features, residents expressed a clear preference for more bread‐and‐butter admissions, whereas the staff prioritized selecting the most complex, challenging, and rare cases from among the day's admissions to give to the residents. (Residents were also very interested in rare cases, suggesting that they saw benefit to admitting patients with a variety of degrees of rarity and complexity.) Residents and faculty seemed to agree that the number of social admissions and outside transfers admitted to teaching services was not ideal.
These perceptions have substantial implications. If the current triage process is to continue, there may be benefit to designing a faculty development project focused on the triage process, which previously has been largely unexamined. Efforts to remove or limit time barriers that prevent perceived educational cases from being admitted to teaching services is also a worthy endeavor (eg, structuring the 2 teams to admit simultaneously so that teaching teams can admit patients back to back without exceeding capacity). In addition, residents may benefit from teaching hospitalists who concentrate educational efforts on the learning that can be extracted from the care of any patient, including admissions that initially seem mundane or purely social.[14] A concerted effort to divert more traditional medicine admissions and fewer unusual cases to the teaching service might improve resident perceptions of the triage process. Further, although the care of any patient can have education benefit, the fact that both groups perceived excessive social admissions in the teaching service suggests that a potential benefit of a nonteaching service (ie, absorbing the most mundane admissions) may not yet be fully realized.
Despite the perceived differences noted on the surveys, we found remarkably few differences between patients admitted to the teaching and nonteaching services. Although both groups rated complexity; outside transfers; being seen at the institution for the first time; and histories of transplantation, cancer, chronic or functional pain, and psychiatric disease as increasing the likelihood of admission to a teaching service, no differences were observed for these factors or their quantifiable surrogates. (Although the overall test for admission type achieved marginal statistical significance, none of the individual admission types were significantly different in post hoc analysis.) Residents, but not faculty, thought that older patients were over‐represented on the teaching service, but their assigned patients were significantly younger than those on the nonteaching service.
These findings have several possible explanations. First, although most hospitalists spend time on teaching and nonteaching services (and therefore are familiar with the patient composition of each), residents get very little exposure to the nonteaching services (until they are senior residents with a rotation on a consulting service). Their impression of inequity may be due to misunderstanding the patient composition of the nonteaching services. Second, the mere existence of a triage role may create false expectations about patient composition; that is, simply by knowing that every admission was chosen for its educational merit, residents may have disproportionate perceptions about those cases judged to have less educational value, even ifas our data suggestassignments to teaching versus nonteaching services are occurring fairly equitably.
Study Limitations
We acknowledge several limitations of our study. First, many factors that were reported as important in the qualitative survey did not lend themselves to objective abstraction from patient records. For example, providers did not specifically document when an admission is purely social, nor was there an objective way to identify difficult patients or families or admissions that were expected to take more time. We attempted to limit the analysis to objective patient metrics that were (1) not influenced by the teaching or nonteaching assignment itself (eg, we avoided discharge diagnoses, which might be entered differently by residents and staff hospitalists) and (2) easily available to triage hospitalists. For the latter reason, we used a prior appointment in the hematology or oncology clinic as a surrogate for cancer patients and a prior psychiatry visit as a surrogate for patients with a history of psychiatric disease. These are naturally inexact surrogates, but they reflect the information a busy hospitalist is likely to access when making patient assignment decisions.
Second, it may well be that assigning patients equitably according to a certain trait is not the same as assigning patients ideally for the educational needs of residents. The patients admitted to our medicine services (teaching and nonteaching) were generally older than 60 years, had complex diagnoses, and had substantial pain. Residents on the teaching services potentially would benefit from an intentionally unbalanced admission policy that shunted patients to the teaching services on the basis of features other than individual perceived educational merit. It must also be borne in mind that resident, and for that matter faculty, perceptions of ideal teaching cases are likely inexact correlates of educational best practices; the ideal role of the triage hospitalist is to admit to the teaching services those patients that will best advance the education of the learners, including a consideration of the goals and objectives of the rotation. Future studies correlating different triage practices to actual educational outcomes would be very helpful.
Third, the analysis could not reliably eliminate patients whose admissions did not represent genuine triage decisions (eg, those assigned to the hospitalist service after the teaching service had reached its capacity or immediately after they had received a complex case). Studying admission decisions prospectively could eliminate this variability, but it could introduce a Hawthorne effect, the negative effects of which likely would outweigh this benefit.
CONCLUSION
Triage hospitalists distributed patients fairly evenly between teaching and nonteaching services, but residents and faculty alike perceived that residents would benefit from more bread‐and‐butter cases. Hospitals considering the addition of a nonteaching service may want to incorporate a faculty development project focused on the triage process to ensure that these traditional medicine cases are assigned to resident services and to ensure that the great teaching case is not considered such because of complexity and acuity alone.
Acknowledgements
The authors thank Elizabeth Jones and Lois Bell for their assistance with survey collection and collation.
Disclosures: This study (institutional review board application #11‐3;002635) was deemed exempt by the Mayo Clinic institutional review board on May 16, 2011. The authors report no conflicts of interest.
The advent of work‐hour restrictions and admission limits for teaching services has led many academic hospitals to implement hospitalist‐run staff (ie, nonteaching) services.[1] Although this practice is not new,[2] it is growing in popularity[3] and has been endorsed as a way to protect resident teaching and prevent excessive workload.[4] One potential benefit is the assignment of more educational cases to teaching services, whereas the nonteaching services receive more patients whose care is presumably relatively mundane or routine.[5]
Despite the rapid growth of this system of educational triage,[6] little is known about the factors considered when teaching versus nonteaching decisions are made. Studies of clinical outcomes for patients assigned to teaching versus nonteaching services have understandably used random assignment,[7, 8] whereas a study finding that patients with unhealthy substance use were more likely to be on teaching services than nonteaching services relied on patient assignment based on the identity of the patient's primary care provider or insurer.[9] In 2009, O'Connor et al. reported that implementation of nonteaching services at 2 hospitals had led to unequal distribution of patients in terms of demographics, diagnosis, and illness severity.[10] Triage decisions were made by either a nurse coordinator or a medical chief resident, and sicker patients (and occasionally good teaching cases) were preferentially placed on the teaching services, reportedly out of respect for the comfort level of the midlevel providers who staffed the nonteaching services.
Our institution has used a system of hospitalist educational triage since 1998. Over that time, residents have often expressed concerns about the assignment of patients to the teaching services, reporting in particular that they receive a disproportionate number of complex cases and outside transfers. In 2006, the hospitalist group attempted to address these concerns by collecting real‐time admission data, but the application of the data was limited by suspicion on both sides of a Hawthorne effect (data not published).
If trainee and hospitalist expectations for what constitutes a great teaching case differ substantially, that difference can have significant implications for resident and medical student teaching, self‐perceived roles, and satisfaction. More significantly, an understanding of what faculty perceive as ideal teaching cases would provide valuable information about the strengths and weaknesses of the teachingnonteaching model, which may prove useful to other academic institutions considering such a system. In this study, we endeavored to understand what residents and hospitalists consider an educational admission and to compare these expectations to the actual triage decisions of hospitalists.
METHODS
Mayo Clinic Hospital (Phoenix, Arizona) has used separate teaching and nonteaching services since opening in 1998. At our institution, like many others,[11] a hospitalist is assigned to take all calls for emergency department (ED) admissions, admissions from outpatient clinics, and transfer requests; this physician directs patients to the teaching or nonteaching service. At the time of our study, the 2 teaching services alternated days in which they admitted up to 7 patients, and the 5 nonteaching services admitted all other patients and provided medicine consultative services for the hospital. Teaching services consisted of 1 hospitalist, 2 senior residents, 2 or 3 first‐year residents, and sometimes 1 third‐ or fourth‐year medical student. Nonteaching services consisted of a hospitalist with intermittent assistance from a physician assistant or nurse practitioner.
Although there are no formal guidelines for the hospitalist triage role, hospitalists are encouraged to assign more educational cases to the teaching services and to allow the residents enough time to address the acute needs of the prior admission before receiving the next admission. Residents are not assigned any patients between 4:00 am and 7:00 am. The goals and objectives for the resident rotation on the medicine teaching service include a list of diagnoses with which residents are expected to become familiar during their residency; triage hospitalists have on‐line access to these goals and objectives.
To assess resident and hospitalist opinions about what types of patients should or should not be admitted to teaching services and to compare those characteristics with those of the patients actually admitted to teaching services, we began by administering a simple, open‐ended survey and asked both groups: (1) In an ideal world, what kinds of patients should be admitted to the internal medicine teaching services at Mayo Clinic Hospital? (2) In the real world, what kinds of patients are admitted to the internal medicine teaching services at Mayo Clinic Hospital?
Ample space was provided for free‐text entries. Residents were additionally asked their postgraduate year level. The survey was administered in April 2011, at which time all residents would have rotated on the medicine teaching services several times. Survey responses were anonymous and were compiled and retyped by someone unfamiliar with the subjects' handwriting.
Two authors (D.L.R. and H.R.L.) reviewed the results of the first survey and used conventional content analysis to group responses into categories and tally them.[12] Responses from hospitalists and residents were used to determine the content for a second, quantitative survey that asked respondents to rate specific possible factors that affected triage decisions on a Likert scale from 1 (Argues against teaching admission) to 5 (Argues for teaching admission). The second survey, administered to the same residents and hospitalists in May 2011, asked: (1) In an ideal world, how do these factors contribute to the decision about which patients should be admitted to the internal medicine teaching services at Mayo Clinic Hospital? (2) In the real world, how do these factors contribute to the decision about which patients are admitted to the internal medicine teaching services at Mayo Clinic Hospital?
Assuming a 3:1 ratio of nonteaching to teaching admissions, we calculated that we would need to analyze 1028 admissions to detect a 10% difference in the proportion of a specific trait present in 50% of patients admitted to the nonteaching service, with the use of a 2‐sided test with 80% statistical power and a significance level of 0.05.
We collected data on patient assignment via retrospective chart review to avoid the possibility of a Hawthorne effect. We studied all admissions to the internal medicine services for a 3‐month period before the administration of the first survey (January 1, 2011 through March 31, 2011). The following patient data were collected: service assignment (teaching vs nonteaching), age, sex, source of admission (ED, direct from clinic, outside transfer, internal transfer from another hospital service), first visit to our institution, prior hematology or oncology visit at our institution (as a surrogate for cancer), prior psychiatry visit at our institution (as a surrogate for psychiatric disease), transplantation history, human immunodeficiency virus (HIV) or acquired immune deficiency syndrome (AIDS) history, chronic or functional pain mentioned in ED or admission note, need for translator, and benefactor status. Additionally, an online calculator was used to determine the Charlson Comorbidity Index score for each patient.[13] We collected actual patient data corresponding to factors reported by survey respondents whenever possible and practical, but not every factor reported by survey respondents was amenable to rigorous analysis; for example, no unbiased method could be devised to rigorously categorize patients whose admissions are likely to take more time or difficult patients and families.
Responses to the second (quantitative) survey and patient data were compared using the Pearson [2] and Fisher exact test for categorical variables and the Student t test or Wilcoxon rank sum test for continuous variables. Categorical variables that achieved statistical significance for overall difference were analyzed on a post hoc basis using the Bonferroni method to control for the overall type I error rate. We also examined the differences between actual and ideal triage decisions using the Wilcoxon signed rank test. Data were analyzed using SAS 9.3 (SAS Institute, Inc., Cary, NC). Statistical significance was defined as P<0.05.
The project was deemed exempt by the Mayo Clinic institutional review board.
RESULTS
We surveyed all categorical internal medicine residents (n=30, 10 each from postgraduate year [PGY]‐1, PGY‐2, and PGY‐3) and hospitalists except the authors (n=21; average years since completing training=13.3; range, 129 years). For both surveys, responses were collected from 29 (96.7%) residents. The nonresponding resident was a PGY‐2. The response rate for hospitalists was 20/21 (95.2%) for the first survey and 16/21 (76.2%) for the second survey.
First Survey
Table 1 compares the most frequent resident and faculty responses to the initial, open‐ended survey about what types of patients should or should not be admitted to teaching services. Residents most commonly indicated that ideal patients were traditional medicine cases (ie, bread‐and‐butter admissions, with 13 residents using that exact phrase), and others supplied specific examples of such cases, including chronic obstructive pulmonary disease, pneumonia, diabetic ketoacidosis, congestive heart failure, chest pain, and gastrointestinal tract bleeding. Only 1 faculty member mentioned bread‐and‐butter admissions, although several listed examples like chest pain and pneumonia. A smaller number of residents pointed to the importance of rare cases, whereas faculty considered rare cases to be ideal for teaching services, followed by variety of pathology and complexity.
Residents (n=29) | Faculty (n=20) | |||
---|---|---|---|---|
Question | Characteristic | No. (%) | Characteristic | No. (%) |
| ||||
In an ideal world, what kinds of patients should be admitted to the internal medicine teaching services at Mayo Clinic Hospital? | Bread‐and butter admissionsb | 14 (44.8) | Rare cases | 9 (45.0) |
Rare cases | 9 (31.0) | Variety of pathology | 7 (35.0) | |
No social admissions | 7 (24.1) | Complex cases | 5 (25.0) | |
New diagnoses instead of chronic management | 4 (13.8) | Variety of complexity | 5 (25.0) | |
Variety of complexity | 4 (13.8) | Patients with HIV/AIDS | 3 (15.0) | |
Diagnostic dilemmas | 3 (15.0) | |||
New diagnoses instead of chronic management | 3 (15.0) | |||
In the real world, what kinds of patients are admitted to the internal medicine teaching services at Mayo Clinic Hospital? | Patients with cancer | 11 (37.9) | Complex patients | 6 (30.0) |
Complex patients | 10 (34.5) | Difficult patients | 5 (25.0) | |
Social admissions | 9 (31.0) | Patients whose admissions are expected to be time consuming | 5 (25.0) | |
Acutely ill patients | 6 (20.7) | Rare cases | 3 (15.0) | |
Variety of pathology | 6 (20.7) | Cases determined by the time of day | 3 (15.0) |
With regard to actual admissions, residents and faculty agreed that they often were complex, but residents were more likely to suggest high rates of patients with cancer (11 residents vs 2 hospitalists) and social admissions (9 residents vs 2 hospitalists). Four residents each believed that they preferentially received elderly patients, outside transfers, and patients with functional pain, and 2 perceived a disproportionate number of patients making their first visit to Mayo Clinic. One hospitalist believed that residents were more likely to receive non‐English speakers.
Second Survey
Table 2 compares the resident and faculty responses to the second, numerical survey regarding ideal admissions to the teaching services. In contrast to the first survey, residents prioritized rare cases as the feature they most associated with ideal teaching admissions. They also placed a premium on variety of pathology, patients with unique findings, and patients likely to be written up or presented. The patients they believed were least appropriate for a teaching service were social admissions or those with placement issues, patients with functional or chronic pain, and benefactors or public figures.
Factor | Resident, n=29 | Faculty, n=16 | P Value |
---|---|---|---|
| |||
Rare diseases | 0.22 | ||
Mean (SD) | 4.8 (0.5) | 4.9 (0.3) | |
Median | 5 | 5 | |
Variety of pathology | 0.22 | ||
Mean (SD) | 4.7 (0.5) | 4.5 (0.5) | |
Median | 5 | 5 | |
Cases that might be written up or presented | 0.35 | ||
Mean (SD) | 4.7 (0.5) | 4.8 (0.6) | |
Median | 5 | 5 | |
Bread‐and‐butter cases | 0.001 | ||
Mean (SD) | 4.6 (0.7) | 3.7 (0.9) | |
Median | 5 | 4 | |
Unique physical findings | 0.67 | ||
Mean (SD) | 4.6 (0.6) | 4.7 (0.5) | |
Median | 5 | 5 | |
Variety of complexity | 0.21 | ||
Mean (SD) | 4.3 (0.7) | 4.1 (0.6) | |
Median | 4 | 4 | |
Variety of acuity | 0.40 | ||
Mean (SD) | 4.2 (0.7) | 4.1 (0.7) | |
Median | 4 | 4 | |
Spectrum of ages | 0.046 | ||
Mean (SD) | 4.1 (0.8) | 3.6 (0.8) | |
Median | 4 | 3 | |
HIV or AIDS | 0.39 | ||
Mean (SD) | 4.1 (0.9) | 4.4 (0.5) | |
Median | 4 | 4 | |
Acutely ill or unstable | 0.54 | ||
Mean (SD) | 4.0 (0.9) | 3.9 (0.6) | |
Median | 4 | 4 | |
Complex patients | 0.94 | ||
Mean (SD) | 4.0 (0.8) | 3.9 (0.6) | |
Median | 4 | 4 | |
Patients at end of life | 0.16 | ||
Mean (SD) | 3.5 (0.8) | 3.1 (0.6) | |
Median | 3 | 3 | |
First‐time Mayo patients | 0.45 | ||
Mean (SD) | 3.5 (0.7) | 3.3 (0.5) | |
Median | 3 | 3 | |
Younger patients | 0.50 | ||
Mean (SD) | 3.5 (0.9) | 3.3 (0.6) | |
Median | 3 | 3 | |
Stable patients | 0.21 | ||
Mean (SD) | 3.3 (0.8) | 3.1 (0.3) | |
Median | 3 | 3 | |
Patients with cancer | 0.67 | ||
Mean (SD) | 3.3 (0.8) | 3.1 (0.4) | |
Median | 3 | 3 | |
Straightforward patients | 0.64 | ||
Mean (SD) | 3.2 (0.8) | 3.1 (0.8) | |
Median | 3 | 3 | |
Older patients | 0.73 | ||
Mean (SD) | 3.2 (0.7) | 3.1 (0.3) | |
Median | 3 | 3 | |
Patients with a history of transplantation | 0.67 | ||
Mean (SD) | 3.1 (1.1) | 3.3 (0.6) | |
Median | 3 | 3 | |
Time of day of admission | 0.71 | ||
Mean (SD) | 3.1 (1.0) | 3.1 (0.5) | |
Median | 3 | 3 | |
Patients with a history of psychiatric illness | 0.59 | ||
Mean (SD) | 3.1 (1.0) | 3.1 (0.6) | |
Median | 3 | 3 | |
Patients who require a translator | 0.49 | ||
Mean (SD) | 3.0 (0.9) | 3.1 (0.5) | |
Median | 3 | 3 | |
Patients whose admissions are expected to take more time | 0.13 | ||
Mean (SD) | 2.9 (0.8) | 3.2 (0.6) | |
Median | 3 | 3 | |
Difficult patients and families | 0.55 | ||
Mean (SD) | 2.8 (1.0) | 2.6 (0.8) | |
Median | 3 | 3 | |
Transfers from other hospitals | 0.11 | ||
Mean (SD) | 2.7 (1.1) | 3.1 (0.3) | |
Median | 3 | 3 | |
Benefactors and public figures | 0.49 | ||
Mean (SD) | 2.7 (1.0) | 2.5 (0.7) | |
Median | 3 | 3 | |
Patients with functional or chronic pain | 0.87 | ||
Mean (SD) | 2.4 (1.1) | 2.4 (1.0) | |
Median | 2 | 3 | |
Social admissions or placement issues | 0.99 | ||
Mean (SD) | 2.1 (1.1) | 2.0 (1.0) | |
Median | 2 | 2 |
Faculty prioritized many of the same features for ideal teaching cases as residents; 4 of their 5 highest‐scoring factors were the same (rare diseases, patients whose cases might be written up or presented, patients with unique physical findings, and variety of pathology). They also agreed on the least ideal features (social admissions or placement issues, patients with functional or chronic pain, and benefactors or public figures). The only significant differences between resident and faculty ratings for ideal teaching cases were for bread‐and‐butter cases and a spectrum of ages.
Discordance between resident and faculty survey responses on actual admission decisions (Table 3) was starker; residents rated several features significantly higher than faculty as features contributing to triage decisions including older patients; patients with functional or chronic pain, social admissions, or placement issues; patients with cancer; transfers from other hospitals; and difficult patients and families. Relative to residents, faculty reported that patients with HIV or AIDS, and patients whose cases were likely to be written up or presented, were more likely to be admitted to teaching services.
Factor | Resident, n=29 | Faculty, n=16 | P Value |
---|---|---|---|
| |||
Rare diseases | 0.14 | ||
Mean (SD) | 4.4 (0.6) | 4.7 (0.6) | |
Median | 4 | 5 | |
Complex patients | 0.83 | ||
Mean (SD) | 4.3 (0.6) | 4.3 (0.6) | |
Median | 4 | 4 | |
Acutely ill or unstable | 0.18 | ||
Mean (SD) | 4.3 (0.7) | 3.9 (0.9) | |
Median | 4 | 4 | |
Unique physical findings | 0.18 | ||
Mean (SD) | 4.1 (0.8) | 4.5 (0.6) | |
Median | 4 | 5 | |
Transfers from other hospitals | 0.003 | ||
Mean (SD) | 4.1 (1.0) | 3.5 (0.5) | |
Median | 4 | 3 | |
Cases that might be written up or presented | 0.03 | ||
Mean (SD) | 4.1 (0.7) | 4.6 (0.6) | |
Median | 4 | 5 | |
Older patients | <0.001 | ||
Mean (SD) | 3.9 (0.8) | 3.0 (0.7) | |
Median | 4 | 3 | |
Time of day of admission | 0.50 | ||
Mean (SD) | 3.9 (1.1) | 3.7 (0.9) | |
Median | 4 | 4 | |
Patients with cancer | 0.01 | ||
Mean (SD) | 3.9 (0.9) | 3.3 (0.5) | |
Median | 4 | 3 | |
Variety of pathology | 0.21 | ||
Mean (SD) | 3.9 (0.8) | 4.2 (0.7) | |
Median | 4 | 4 | |
Patients whose admissions are expected to take more time | 0.13 | ||
Mean (SD) | 3.9 (1.0) | 3.4 (0.9) | |
Median | 4 | 3 | |
HIV or AIDS | 0.008 | ||
Mean (SD) | 3.8 (0.9) | 4.5 (0.5) | |
Median | 4 | 4.5 | |
Variety of complexity | 0.31 | ||
Mean (SD) | 3.7 (0.9) | 3.9 (0.6) | |
Median | 3.5 | 4 | |
Bread‐and‐butter cases | 0.07 | ||
Mean (SD) | 3.6 (1.0) | 2.9 (1.2) | |
Median | 3 | 3 | |
First‐time Mayo patients | 0.82 | ||
Mean (SD) | 3.6 (0.9) | 3.5 (0.7) | |
Median | 3 | 3 | |
Patients with functional or chronic pain | 0.004 | ||
Mean (SD) | 3.6 (1.0) | 2.8 (0.7) | |
Median | 4 | 3 | |
Social admissions or placement issues | 0.03 | ||
Mean (SD) | 3.5 (1.2) | 2.7 (0.9) | |
Median | 4 | 3 | |
Variety of acuity | 0.25 | ||
Mean (SD) | 3.5 (0.8) | 3.7 (0.6) | |
Median | 3 | 4 | |
Difficult patients and families | 0.03 | ||
Mean (SD) | 3.4 (0.9) | 2.8 (0.7) | |
Median | 3 | 3 | |
Patients at end of life | 0.10 | ||
Mean (SD) | 3.4 (0.8) | 3.0 (0.5) | |
Median | 3 | 3 | |
Spectrum of ages | 0.80 | ||
Mean (SD) | 3.3 (0.7) | 3.3 (0.6) | |
Median | 3 | 3 | |
Patients with a history of psychiatric illness | 0.81 | ||
Mean (SD) | 3.3 (0.9) | 3.1 (0.6) | |
Median | 3 | 3 | |
Patients with a history of transplantation | 0.25 | ||
Mean (SD) | 3.2 (0.9) | 3.5 (0.5) | |
Median | 3 | 3 | |
Patients who require a translator | 0.60 | ||
Mean (SD) | 3.2 (0.7) | 3.2 (0.6) | |
Median | 3 | 3 | |
Younger patients | 0.42 | ||
Mean (SD) | 3.0 (0.9) | 3.1 (0.4) | |
Median | 3 | 3 | |
Benefactors and public figures | 0.09 | ||
Mean (SD) | 2.9 (1.0) | 2.3 (0.7) | |
Median | 3 | 2 | |
Straightforward patients | 0.18 | ||
Mean (SD) | 2.8 (1.0) | 2.4 (1.0) | |
Median | 2.5 | 2 | |
Stable patients | 0.53 | ||
Mean (SD) | 2.7 (1.0) | 2.8 (0.7) | |
Median | 3 | 3 |
Comparing resident survey ratings for ideal versus actual triage decisions gave some insight into the features that they thought were inappropriately emphasized or ignored when triage decisions were made. Differences in resident scores for ideal versus actual admissions were significantly different for 16 of 28 items (data available upon request), suggesting a degree of perceived discordance. The largest positive differences (ie, features they valued in teaching admissions but thought were less represented in actual admissions) were for bread‐and‐butter admissions, variety of pathology, a spectrum of ages, and variety of acuity. The largest negative differences (ie, features they thought were well represented in actual admissions but were less valuable) were for social admissions or placement issues, transfers from other hospitals, patients with functional or chronic pain, and patients whose admissions were expected to take more time.
In terms of ideal versus actual triage decisions, faculty reported less discordance than residents; ideal and actual triage behavior differed significantly only for 4 of 28 items (data available upon request). They did agree with residents about the relative lack of bread‐and‐butter admissions and the over‐representation of social admissions or placement issues and transfers from other hospitals. They additionally noted a lack of straightforward cases.
We reviewed records of the 1426 patients admitted to the internal medicine services during the study period. Of these, 359 (25.2%) were assigned to the teaching services. Patient characteristics are summarized in Table 4.
Characteristic | Teaching Service, n=359 | Nonteaching Service, n=1,067 | P Value |
---|---|---|---|
| |||
Age, y, mean (SD) | 66.7 (16.5) | 69.3 (15.7) | 0.008 |
Admission type, No. (%) | 0.049 | ||
Admission from the emergency department | 315 (87.7) | 915 (85.8) | 0.34 |
Direct admission from Mayo outpatient clinic | 27 (7.5) | 114 (10.7) | 0.08 |
Transfer from another institution | 16 (4.5) | 27 (2.5) | 0.06 |
Internal transfer from a different hospital service | 1 (0.3) | 11 (1.0) | 0.31 |
First‐time Mayo patient, No. (%) | 61 (17.0) | 175 (16.4) | 0.79 |
Prior hematology or oncology visit, No. (%) | 86 (24.0) | 235 (22.0) | 0.45 |
History of transplantation, No. (%) | 20 (5.6) | 52 (4.9) | 0.60 |
Prior psychiatry visit, No. (%) | 53 (14.8) | 122 (11.4) | 0.10 |
History of chronic or functional pain, No. (%) | 122 (34.0) | 330 (30.9) | 0.28 |
Required translator, No. (%) | 5 (1.4) | 14 (1.3) | 0.91 |
Benefactor, No. (%) | 5 (1.4) | 24 (2.2) | 0.32 |
Charlson comorbidity score, mean (SD) | 2.7 (2.5) | 2.6 (2.5) | 0.49 |
DISCUSSION
The results of our qualitative and quantitative surveys showed significant differences between resident and staff perceptions of the faculty triage role. Although both groups similarly valued many features, residents expressed a clear preference for more bread‐and‐butter admissions, whereas the staff prioritized selecting the most complex, challenging, and rare cases from among the day's admissions to give to the residents. (Residents were also very interested in rare cases, suggesting that they saw benefit to admitting patients with a variety of degrees of rarity and complexity.) Residents and faculty seemed to agree that the number of social admissions and outside transfers admitted to teaching services was not ideal.
These perceptions have substantial implications. If the current triage process is to continue, there may be benefit to designing a faculty development project focused on the triage process, which previously has been largely unexamined. Efforts to remove or limit time barriers that prevent perceived educational cases from being admitted to teaching services is also a worthy endeavor (eg, structuring the 2 teams to admit simultaneously so that teaching teams can admit patients back to back without exceeding capacity). In addition, residents may benefit from teaching hospitalists who concentrate educational efforts on the learning that can be extracted from the care of any patient, including admissions that initially seem mundane or purely social.[14] A concerted effort to divert more traditional medicine admissions and fewer unusual cases to the teaching service might improve resident perceptions of the triage process. Further, although the care of any patient can have education benefit, the fact that both groups perceived excessive social admissions in the teaching service suggests that a potential benefit of a nonteaching service (ie, absorbing the most mundane admissions) may not yet be fully realized.
Despite the perceived differences noted on the surveys, we found remarkably few differences between patients admitted to the teaching and nonteaching services. Although both groups rated complexity; outside transfers; being seen at the institution for the first time; and histories of transplantation, cancer, chronic or functional pain, and psychiatric disease as increasing the likelihood of admission to a teaching service, no differences were observed for these factors or their quantifiable surrogates. (Although the overall test for admission type achieved marginal statistical significance, none of the individual admission types were significantly different in post hoc analysis.) Residents, but not faculty, thought that older patients were over‐represented on the teaching service, but their assigned patients were significantly younger than those on the nonteaching service.
These findings have several possible explanations. First, although most hospitalists spend time on teaching and nonteaching services (and therefore are familiar with the patient composition of each), residents get very little exposure to the nonteaching services (until they are senior residents with a rotation on a consulting service). Their impression of inequity may be due to misunderstanding the patient composition of the nonteaching services. Second, the mere existence of a triage role may create false expectations about patient composition; that is, simply by knowing that every admission was chosen for its educational merit, residents may have disproportionate perceptions about those cases judged to have less educational value, even ifas our data suggestassignments to teaching versus nonteaching services are occurring fairly equitably.
Study Limitations
We acknowledge several limitations of our study. First, many factors that were reported as important in the qualitative survey did not lend themselves to objective abstraction from patient records. For example, providers did not specifically document when an admission is purely social, nor was there an objective way to identify difficult patients or families or admissions that were expected to take more time. We attempted to limit the analysis to objective patient metrics that were (1) not influenced by the teaching or nonteaching assignment itself (eg, we avoided discharge diagnoses, which might be entered differently by residents and staff hospitalists) and (2) easily available to triage hospitalists. For the latter reason, we used a prior appointment in the hematology or oncology clinic as a surrogate for cancer patients and a prior psychiatry visit as a surrogate for patients with a history of psychiatric disease. These are naturally inexact surrogates, but they reflect the information a busy hospitalist is likely to access when making patient assignment decisions.
Second, it may well be that assigning patients equitably according to a certain trait is not the same as assigning patients ideally for the educational needs of residents. The patients admitted to our medicine services (teaching and nonteaching) were generally older than 60 years, had complex diagnoses, and had substantial pain. Residents on the teaching services potentially would benefit from an intentionally unbalanced admission policy that shunted patients to the teaching services on the basis of features other than individual perceived educational merit. It must also be borne in mind that resident, and for that matter faculty, perceptions of ideal teaching cases are likely inexact correlates of educational best practices; the ideal role of the triage hospitalist is to admit to the teaching services those patients that will best advance the education of the learners, including a consideration of the goals and objectives of the rotation. Future studies correlating different triage practices to actual educational outcomes would be very helpful.
Third, the analysis could not reliably eliminate patients whose admissions did not represent genuine triage decisions (eg, those assigned to the hospitalist service after the teaching service had reached its capacity or immediately after they had received a complex case). Studying admission decisions prospectively could eliminate this variability, but it could introduce a Hawthorne effect, the negative effects of which likely would outweigh this benefit.
CONCLUSION
Triage hospitalists distributed patients fairly evenly between teaching and nonteaching services, but residents and faculty alike perceived that residents would benefit from more bread‐and‐butter cases. Hospitals considering the addition of a nonteaching service may want to incorporate a faculty development project focused on the triage process to ensure that these traditional medicine cases are assigned to resident services and to ensure that the great teaching case is not considered such because of complexity and acuity alone.
Acknowledgements
The authors thank Elizabeth Jones and Lois Bell for their assistance with survey collection and collation.
Disclosures: This study (institutional review board application #11‐3;002635) was deemed exempt by the Mayo Clinic institutional review board on May 16, 2011. The authors report no conflicts of interest.
- Duty hours for resident physicians: tough choices for teaching hospitals. N Engl J Med. 2002;347(16):1275–1278. .
- A randomized, controlled trial of an attending staff service in general internal medicine. Med Care. 1991;29(7 suppl):JS31–JS40. , , , , .
- Non‐housestaff medicine services in academic centers: models and challenges. J Hosp Med. 2008;3(3):247–255. , , , , .
- Education Committee of the American College of Physicians. Redesigning training for internal medicine. Ann Intern Med. 2006;144(12):927–932. , , ;
- Improving resource utilization in a teaching hospital: development of a nonteaching service for chest pain admissions. Acad Med. 2006;81(5):432–435. , , , , .
- Hospitalists and an innovative emergency department admission process. J Gen Intern Med. 2004;19(3):266–268. , , .
- Comparison of resource utilization and clinical outcomes between teaching and nonteaching medical services. J Hosp Med. 2007;2(3):150–157. , , , , .
- A comparative study of unscheduled hospital readmissions in a resident‐staffed teaching service and a hospitalist‐based service. South Med J. 2009;102(2):145–149. , , , .
- Prevalence of unhealthy substance use on teaching and hospitalist medical services: implications for education. Am J Addict. 2012;21(2):111–119. , , , et al.
- The effect of nonteaching services on the distribution of inpatient cases for internal medicine residents. Acad Med. 2009;84(2):220–225. , , , et al.
- http://www.todayshospita list.com/index.php?b=articles_read15(9):1277–1288. Teaching and nonteaching services: separate no more? Today's Hospitalist website. Available at:
- Charlson comorbidity scoring system: estimating prognosis for dialysis patients. Touchcalc website. Available at: http://www.touchcalc.com/calculators/cci_js#t2_probability. Accessed January 15, 2014.
- Curiosity. Ann Intern Med. 1999;130(1):70–71. .
- Duty hours for resident physicians: tough choices for teaching hospitals. N Engl J Med. 2002;347(16):1275–1278. .
- A randomized, controlled trial of an attending staff service in general internal medicine. Med Care. 1991;29(7 suppl):JS31–JS40. , , , , .
- Non‐housestaff medicine services in academic centers: models and challenges. J Hosp Med. 2008;3(3):247–255. , , , , .
- Education Committee of the American College of Physicians. Redesigning training for internal medicine. Ann Intern Med. 2006;144(12):927–932. , , ;
- Improving resource utilization in a teaching hospital: development of a nonteaching service for chest pain admissions. Acad Med. 2006;81(5):432–435. , , , , .
- Hospitalists and an innovative emergency department admission process. J Gen Intern Med. 2004;19(3):266–268. , , .
- Comparison of resource utilization and clinical outcomes between teaching and nonteaching medical services. J Hosp Med. 2007;2(3):150–157. , , , , .
- A comparative study of unscheduled hospital readmissions in a resident‐staffed teaching service and a hospitalist‐based service. South Med J. 2009;102(2):145–149. , , , .
- Prevalence of unhealthy substance use on teaching and hospitalist medical services: implications for education. Am J Addict. 2012;21(2):111–119. , , , et al.
- The effect of nonteaching services on the distribution of inpatient cases for internal medicine residents. Acad Med. 2009;84(2):220–225. , , , et al.
- http://www.todayshospita list.com/index.php?b=articles_read15(9):1277–1288. Teaching and nonteaching services: separate no more? Today's Hospitalist website. Available at:
- Charlson comorbidity scoring system: estimating prognosis for dialysis patients. Touchcalc website. Available at: http://www.touchcalc.com/calculators/cci_js#t2_probability. Accessed January 15, 2014.
- Curiosity. Ann Intern Med. 1999;130(1):70–71. .
© 2014 Society of Hospital Medicine
LISTEN NOW! UC San Francisco's Michelle Mourad Encourages Fellow Hospitalists To Get Involved in Quality Projects
Click here to listen to more of our interview with Dr. Mourad
Click here to listen to more of our interview with Dr. Mourad
Click here to listen to more of our interview with Dr. Mourad
Listen Now! American Enterprise Institute's Scott Gottlieb, MD, Talks About the Impact the Affordable Care Act Will Have on Hospitalists
A day in the life of a rheumatologist
7:00 a.m. When they called me for this consult on this young female with known lupus presenting with pleuritic chest pain, they didn’t tell me that (a) she has a history of pleural effusions, and (b) her creatinine is 4.9 mg/dL.
8:00 a.m. Waiting for my patient to be roomed. We’re implementing a new electronic health record, so I have to wait for the medical assistant (MA) to finish her tasks: input the patient’s medications, take his vital signs, and ask for his chief complaint.
8:20 a.m. Patient is still not ready for me. Who thought it would be a good idea for the MA to take the patient’s medications? It’d be so much more efficient if I did it myself.
9:00 a.m. Finally finished with the first patient. It was a follow-up visit that was scheduled as 15 minutes. I am now 45 minutes behind schedule. Thankfully, the MA managed to use the 45 minutes to room the 8:15 patient.
12:30 p.m. Whew, I just finished my morning. I start again in 30 minutes. I am never going to finish these 12 charts in 30 minutes. Also, I am hungry. If I don’t eat now, I am going to have my MA for lunch.
12:45 p.m. Speaking to Dr. Winchester from Blue Cross to get approval for a contrast MRI of the right foot. (This call may be recorded. What did your x-rays show? Have you failed conservative treatment? Will it change management? Here’s your approval number.)
1:00 p.m. The new patient is here. She is the proud owner of a very long med list. It’ll probably take the MA 30 minutes to get through all that. Let me call dermatology in the meantime; I need a full-thickness skin biopsy on Mrs. Rodrigues. (One week later, biopsy shows polyarteritis nodosa.)
3:15 p.m. I just finished a visit with Silvi. Her rheumatoid arthritis is quiescent, but she is in tears. Not only did her mother die unexpectedly from a ruptured aneurysm 2 months ago, she has just received a new diagnosis of breast cancer, and her husband lost his job. I can’t make this stuff up. That was an emotionally draining visit. I need a drink. Oh wait, there are no drinks to be had at a doctor’s office. Maybe the drug rep brought some ice cream.
3:20 p.m. Some ice cream regret going on here.
4:40 p.m. Just got done with a new-patient consultation for a "positive" antinuclear antibody test of 1:40 and a positive systems review. I’m exhausted.
6:15 p.m. Returning phone calls. Mrs. Greggerson is regaling me with details of her ablutions.
6:35 p.m. Filling out prior authorization forms for a biologic. Among the questions: A1c, T score, growth velocity, Mini-Mental State Exam, free and total testosterone, hepatitis C viral load and genotype. I would like to officially nominate this form for Most Number of Irrelevant Questions Ever.
7:00 p.m. Finally, last prior-authorization form for the day. Wait ... it’s for methotrexate? Since when have I needed to get prior authorization for methotrexate? I didn’t think it was even possible for me to get any angrier after the Mini-Mental State question.
8:00 p.m. Finally home. I’m too beat to go to the gym. My good decision–making reserves are exhausted. I would rather have a glass of red. The resveratrol will do me more good than a workout.
Dr. Chan practices rheumatology in Pawtucket, R.I.
7:00 a.m. When they called me for this consult on this young female with known lupus presenting with pleuritic chest pain, they didn’t tell me that (a) she has a history of pleural effusions, and (b) her creatinine is 4.9 mg/dL.
8:00 a.m. Waiting for my patient to be roomed. We’re implementing a new electronic health record, so I have to wait for the medical assistant (MA) to finish her tasks: input the patient’s medications, take his vital signs, and ask for his chief complaint.
8:20 a.m. Patient is still not ready for me. Who thought it would be a good idea for the MA to take the patient’s medications? It’d be so much more efficient if I did it myself.
9:00 a.m. Finally finished with the first patient. It was a follow-up visit that was scheduled as 15 minutes. I am now 45 minutes behind schedule. Thankfully, the MA managed to use the 45 minutes to room the 8:15 patient.
12:30 p.m. Whew, I just finished my morning. I start again in 30 minutes. I am never going to finish these 12 charts in 30 minutes. Also, I am hungry. If I don’t eat now, I am going to have my MA for lunch.
12:45 p.m. Speaking to Dr. Winchester from Blue Cross to get approval for a contrast MRI of the right foot. (This call may be recorded. What did your x-rays show? Have you failed conservative treatment? Will it change management? Here’s your approval number.)
1:00 p.m. The new patient is here. She is the proud owner of a very long med list. It’ll probably take the MA 30 minutes to get through all that. Let me call dermatology in the meantime; I need a full-thickness skin biopsy on Mrs. Rodrigues. (One week later, biopsy shows polyarteritis nodosa.)
3:15 p.m. I just finished a visit with Silvi. Her rheumatoid arthritis is quiescent, but she is in tears. Not only did her mother die unexpectedly from a ruptured aneurysm 2 months ago, she has just received a new diagnosis of breast cancer, and her husband lost his job. I can’t make this stuff up. That was an emotionally draining visit. I need a drink. Oh wait, there are no drinks to be had at a doctor’s office. Maybe the drug rep brought some ice cream.
3:20 p.m. Some ice cream regret going on here.
4:40 p.m. Just got done with a new-patient consultation for a "positive" antinuclear antibody test of 1:40 and a positive systems review. I’m exhausted.
6:15 p.m. Returning phone calls. Mrs. Greggerson is regaling me with details of her ablutions.
6:35 p.m. Filling out prior authorization forms for a biologic. Among the questions: A1c, T score, growth velocity, Mini-Mental State Exam, free and total testosterone, hepatitis C viral load and genotype. I would like to officially nominate this form for Most Number of Irrelevant Questions Ever.
7:00 p.m. Finally, last prior-authorization form for the day. Wait ... it’s for methotrexate? Since when have I needed to get prior authorization for methotrexate? I didn’t think it was even possible for me to get any angrier after the Mini-Mental State question.
8:00 p.m. Finally home. I’m too beat to go to the gym. My good decision–making reserves are exhausted. I would rather have a glass of red. The resveratrol will do me more good than a workout.
Dr. Chan practices rheumatology in Pawtucket, R.I.
7:00 a.m. When they called me for this consult on this young female with known lupus presenting with pleuritic chest pain, they didn’t tell me that (a) she has a history of pleural effusions, and (b) her creatinine is 4.9 mg/dL.
8:00 a.m. Waiting for my patient to be roomed. We’re implementing a new electronic health record, so I have to wait for the medical assistant (MA) to finish her tasks: input the patient’s medications, take his vital signs, and ask for his chief complaint.
8:20 a.m. Patient is still not ready for me. Who thought it would be a good idea for the MA to take the patient’s medications? It’d be so much more efficient if I did it myself.
9:00 a.m. Finally finished with the first patient. It was a follow-up visit that was scheduled as 15 minutes. I am now 45 minutes behind schedule. Thankfully, the MA managed to use the 45 minutes to room the 8:15 patient.
12:30 p.m. Whew, I just finished my morning. I start again in 30 minutes. I am never going to finish these 12 charts in 30 minutes. Also, I am hungry. If I don’t eat now, I am going to have my MA for lunch.
12:45 p.m. Speaking to Dr. Winchester from Blue Cross to get approval for a contrast MRI of the right foot. (This call may be recorded. What did your x-rays show? Have you failed conservative treatment? Will it change management? Here’s your approval number.)
1:00 p.m. The new patient is here. She is the proud owner of a very long med list. It’ll probably take the MA 30 minutes to get through all that. Let me call dermatology in the meantime; I need a full-thickness skin biopsy on Mrs. Rodrigues. (One week later, biopsy shows polyarteritis nodosa.)
3:15 p.m. I just finished a visit with Silvi. Her rheumatoid arthritis is quiescent, but she is in tears. Not only did her mother die unexpectedly from a ruptured aneurysm 2 months ago, she has just received a new diagnosis of breast cancer, and her husband lost his job. I can’t make this stuff up. That was an emotionally draining visit. I need a drink. Oh wait, there are no drinks to be had at a doctor’s office. Maybe the drug rep brought some ice cream.
3:20 p.m. Some ice cream regret going on here.
4:40 p.m. Just got done with a new-patient consultation for a "positive" antinuclear antibody test of 1:40 and a positive systems review. I’m exhausted.
6:15 p.m. Returning phone calls. Mrs. Greggerson is regaling me with details of her ablutions.
6:35 p.m. Filling out prior authorization forms for a biologic. Among the questions: A1c, T score, growth velocity, Mini-Mental State Exam, free and total testosterone, hepatitis C viral load and genotype. I would like to officially nominate this form for Most Number of Irrelevant Questions Ever.
7:00 p.m. Finally, last prior-authorization form for the day. Wait ... it’s for methotrexate? Since when have I needed to get prior authorization for methotrexate? I didn’t think it was even possible for me to get any angrier after the Mini-Mental State question.
8:00 p.m. Finally home. I’m too beat to go to the gym. My good decision–making reserves are exhausted. I would rather have a glass of red. The resveratrol will do me more good than a workout.
Dr. Chan practices rheumatology in Pawtucket, R.I.
Legislation’s privacy exceptions for psychiatric patients are concerning
Like many of you, I’m currently in New York City for 5 days of psychiatry and psychiatrists, 24/7. I’m hoping there will be a bagel with lox in there somewhere as well.
I wanted to talk about one section of Rep. Tim Murphy’s (R-Pa.) proposed legislation, H.R. 3717, the Helping Families in Mental Health Crisis Act. If you’re not familiar with it, the legislation intends to overhaul a broken mental health system in the United States. One component of the bill, Section 301 located on page 44, deals with modifying HIPAA such that mental health providers can speak with caregivers and family members. Rep. Murphy – who is also a psychologist – has noted in his television appearance and in public testimony that HIPAA is misinterpreted such that families are sometimes told they may not provide historical information about the patient. HIPAA does not actually prevent a mental health professional from listening to anyone’s free speech, but there seem to be times when the involved parties believe this is the case.
In addition, Rep. Murphy noted that HIPAA prevents clinicians from releasing information to caretakers that might help in providing for outpatient care – specifically for releasing medication information and follow-up appointments to those who may be responsible for helping patients negotiate these crucial items.
The proposed legislation reads:
"Caregiver Access to Information: ...to an individual with a serious mental illness who does not provide consent for the disclosure of protected health information to a caregiver of such individual, the caregiver shall be treated by a covered entity as a personal representative ... when the provider furnishing services to the individual reasonably believes it is necessary for protected health information of the individual to be made available to the caregiver in order to protect the health, safety, or welfare of such individuals or the safety of one or more other individuals."
The bill goes on to define "caregiver" as an immediate family member, an individual who assumes primary responsibility for providing for the patient’s basic needs, or a personal representative as determined by law. I think we all agree that collaboration and communication are essential to the care of our patients, and so I applaud these efforts. I worry, however, about the unintended consequences and what roads this might lead us down.
Long before we had HIPAA, we had requirements for patient confidentiality. I, like Rep. Murphy, believe that HIPAA gets distorted. "We need to let your family know your discharge medications and follow-up appointments," is not often met with resistance, but if it is, shouldn’t that be respected? What if patients have valid reasons for not wanting family to know their medications? What if they feel their family is too intrusive, or is part of the problem? Such legislation might suggest that the family is always right and the patient is always wrong.
While the intent (as I’ve understood it from Rep. Murphy’s speeches) is to allow hospitals to tell families, "Yes, your loved [one] has been admitted to our inpatient unit," or to allow well-negotiated follow-up to prevent relapse, might such legislation lead patients to believe that the content of their discussions with mental health professionals can be relayed to others against their will? Might it serve as one more reason for a troubled individual to avoid care?
From a psychiatrist’s point of view, I might be concerned that I would agree with a patient that information should not be released to family, and nothing about this law would then force me to release it. But would family members feel the law says otherwise? Will they contend, "My family member is mentally ill so HIPAA does not apply, and you must release information to me?" While any given psychiatrist might choose not to release information on any given patient, I wonder if this might be setting us up to be at odds with families, and that would not be a good thing. Much as I’m no fan of HIPAA for many reasons, people do understand the concept that confidentiality is required by law. Perhaps I’m reading too much into this?
Finally, we all agree that eliminating stigma is a good thing when it comes to facilitating voluntary care for those who might need it. But I wonder if we can say that people with mental illnesses are just like everyone else, that this is a medical condition just like other conditions, but for this select group of people they lose their right to privacy, much as children have no right to medical privacy. Might that add to the stigma of mental illness?
I don’t have an answer. I believe the intentions of the Helping Families in Mental Health Crisis Act are good, and I believe they target weaknesses in our system. But I also worry that the legislation might create as many problems as it might fix.
The comments feature of the Clinical Psychiatry News website is turned off for the moment, and I would love to hear your thoughts. Please do e-mail with your comments; I can be reached at [email protected], or you may comment on a similar post here.
Dr. Miller is a coauthor of "Shrink Rap: Three Psychiatrists Explain Their Work" (Baltimore: the Johns Hopkins University Press, 2011).
Like many of you, I’m currently in New York City for 5 days of psychiatry and psychiatrists, 24/7. I’m hoping there will be a bagel with lox in there somewhere as well.
I wanted to talk about one section of Rep. Tim Murphy’s (R-Pa.) proposed legislation, H.R. 3717, the Helping Families in Mental Health Crisis Act. If you’re not familiar with it, the legislation intends to overhaul a broken mental health system in the United States. One component of the bill, Section 301 located on page 44, deals with modifying HIPAA such that mental health providers can speak with caregivers and family members. Rep. Murphy – who is also a psychologist – has noted in his television appearance and in public testimony that HIPAA is misinterpreted such that families are sometimes told they may not provide historical information about the patient. HIPAA does not actually prevent a mental health professional from listening to anyone’s free speech, but there seem to be times when the involved parties believe this is the case.
In addition, Rep. Murphy noted that HIPAA prevents clinicians from releasing information to caretakers that might help in providing for outpatient care – specifically for releasing medication information and follow-up appointments to those who may be responsible for helping patients negotiate these crucial items.
The proposed legislation reads:
"Caregiver Access to Information: ...to an individual with a serious mental illness who does not provide consent for the disclosure of protected health information to a caregiver of such individual, the caregiver shall be treated by a covered entity as a personal representative ... when the provider furnishing services to the individual reasonably believes it is necessary for protected health information of the individual to be made available to the caregiver in order to protect the health, safety, or welfare of such individuals or the safety of one or more other individuals."
The bill goes on to define "caregiver" as an immediate family member, an individual who assumes primary responsibility for providing for the patient’s basic needs, or a personal representative as determined by law. I think we all agree that collaboration and communication are essential to the care of our patients, and so I applaud these efforts. I worry, however, about the unintended consequences and what roads this might lead us down.
Long before we had HIPAA, we had requirements for patient confidentiality. I, like Rep. Murphy, believe that HIPAA gets distorted. "We need to let your family know your discharge medications and follow-up appointments," is not often met with resistance, but if it is, shouldn’t that be respected? What if patients have valid reasons for not wanting family to know their medications? What if they feel their family is too intrusive, or is part of the problem? Such legislation might suggest that the family is always right and the patient is always wrong.
While the intent (as I’ve understood it from Rep. Murphy’s speeches) is to allow hospitals to tell families, "Yes, your loved [one] has been admitted to our inpatient unit," or to allow well-negotiated follow-up to prevent relapse, might such legislation lead patients to believe that the content of their discussions with mental health professionals can be relayed to others against their will? Might it serve as one more reason for a troubled individual to avoid care?
From a psychiatrist’s point of view, I might be concerned that I would agree with a patient that information should not be released to family, and nothing about this law would then force me to release it. But would family members feel the law says otherwise? Will they contend, "My family member is mentally ill so HIPAA does not apply, and you must release information to me?" While any given psychiatrist might choose not to release information on any given patient, I wonder if this might be setting us up to be at odds with families, and that would not be a good thing. Much as I’m no fan of HIPAA for many reasons, people do understand the concept that confidentiality is required by law. Perhaps I’m reading too much into this?
Finally, we all agree that eliminating stigma is a good thing when it comes to facilitating voluntary care for those who might need it. But I wonder if we can say that people with mental illnesses are just like everyone else, that this is a medical condition just like other conditions, but for this select group of people they lose their right to privacy, much as children have no right to medical privacy. Might that add to the stigma of mental illness?
I don’t have an answer. I believe the intentions of the Helping Families in Mental Health Crisis Act are good, and I believe they target weaknesses in our system. But I also worry that the legislation might create as many problems as it might fix.
The comments feature of the Clinical Psychiatry News website is turned off for the moment, and I would love to hear your thoughts. Please do e-mail with your comments; I can be reached at [email protected], or you may comment on a similar post here.
Dr. Miller is a coauthor of "Shrink Rap: Three Psychiatrists Explain Their Work" (Baltimore: the Johns Hopkins University Press, 2011).
Like many of you, I’m currently in New York City for 5 days of psychiatry and psychiatrists, 24/7. I’m hoping there will be a bagel with lox in there somewhere as well.
I wanted to talk about one section of Rep. Tim Murphy’s (R-Pa.) proposed legislation, H.R. 3717, the Helping Families in Mental Health Crisis Act. If you’re not familiar with it, the legislation intends to overhaul a broken mental health system in the United States. One component of the bill, Section 301 located on page 44, deals with modifying HIPAA such that mental health providers can speak with caregivers and family members. Rep. Murphy – who is also a psychologist – has noted in his television appearance and in public testimony that HIPAA is misinterpreted such that families are sometimes told they may not provide historical information about the patient. HIPAA does not actually prevent a mental health professional from listening to anyone’s free speech, but there seem to be times when the involved parties believe this is the case.
In addition, Rep. Murphy noted that HIPAA prevents clinicians from releasing information to caretakers that might help in providing for outpatient care – specifically for releasing medication information and follow-up appointments to those who may be responsible for helping patients negotiate these crucial items.
The proposed legislation reads:
"Caregiver Access to Information: ...to an individual with a serious mental illness who does not provide consent for the disclosure of protected health information to a caregiver of such individual, the caregiver shall be treated by a covered entity as a personal representative ... when the provider furnishing services to the individual reasonably believes it is necessary for protected health information of the individual to be made available to the caregiver in order to protect the health, safety, or welfare of such individuals or the safety of one or more other individuals."
The bill goes on to define "caregiver" as an immediate family member, an individual who assumes primary responsibility for providing for the patient’s basic needs, or a personal representative as determined by law. I think we all agree that collaboration and communication are essential to the care of our patients, and so I applaud these efforts. I worry, however, about the unintended consequences and what roads this might lead us down.
Long before we had HIPAA, we had requirements for patient confidentiality. I, like Rep. Murphy, believe that HIPAA gets distorted. "We need to let your family know your discharge medications and follow-up appointments," is not often met with resistance, but if it is, shouldn’t that be respected? What if patients have valid reasons for not wanting family to know their medications? What if they feel their family is too intrusive, or is part of the problem? Such legislation might suggest that the family is always right and the patient is always wrong.
While the intent (as I’ve understood it from Rep. Murphy’s speeches) is to allow hospitals to tell families, "Yes, your loved [one] has been admitted to our inpatient unit," or to allow well-negotiated follow-up to prevent relapse, might such legislation lead patients to believe that the content of their discussions with mental health professionals can be relayed to others against their will? Might it serve as one more reason for a troubled individual to avoid care?
From a psychiatrist’s point of view, I might be concerned that I would agree with a patient that information should not be released to family, and nothing about this law would then force me to release it. But would family members feel the law says otherwise? Will they contend, "My family member is mentally ill so HIPAA does not apply, and you must release information to me?" While any given psychiatrist might choose not to release information on any given patient, I wonder if this might be setting us up to be at odds with families, and that would not be a good thing. Much as I’m no fan of HIPAA for many reasons, people do understand the concept that confidentiality is required by law. Perhaps I’m reading too much into this?
Finally, we all agree that eliminating stigma is a good thing when it comes to facilitating voluntary care for those who might need it. But I wonder if we can say that people with mental illnesses are just like everyone else, that this is a medical condition just like other conditions, but for this select group of people they lose their right to privacy, much as children have no right to medical privacy. Might that add to the stigma of mental illness?
I don’t have an answer. I believe the intentions of the Helping Families in Mental Health Crisis Act are good, and I believe they target weaknesses in our system. But I also worry that the legislation might create as many problems as it might fix.
The comments feature of the Clinical Psychiatry News website is turned off for the moment, and I would love to hear your thoughts. Please do e-mail with your comments; I can be reached at [email protected], or you may comment on a similar post here.
Dr. Miller is a coauthor of "Shrink Rap: Three Psychiatrists Explain Their Work" (Baltimore: the Johns Hopkins University Press, 2011).
Liquid droplets help explain cell migration
Scientists have discovered an unexpected link between the shape of a cell and its migration efficiency, and they’ve explained its physics using a model of a liquid droplet.
Cell migration is achieved through the movement of the cell’s membrane, which is powered by the action of a protein network inside the cell.
This interaction is affected by the cell’s overall shape, but exactly how this takes place has been unclear.
Research published in Current Biology provides some insight.
The first step in cell migration occurs when the cell extends its front edge—a process called protrusion. This is driven by the growth of actin filaments, which push the cell membrane from inside. At the same time, membrane tension controls protrusion by providing resistance and protecting the cell from over-extending.
But physical laws dictate that the shape of the cell membrane must play a role in the balance between force exerted by actin and the resisting membrane tension. This was not taken into account in previous studies, which used 2D models of migrating cells.
Now, Chiara Gabella, PhD, of Ecole Polytechnique Fédérale de Lausanne in Switzerland, and her colleagues have used a 3D model to better describe the relationship between cell protrusion, shape, and membrane tension.
The scientists developed a way to evaluate the 3D shape of migrating fish epidermal keratocytes by observing the cells in a chamber filled with a fluorescent solution.
The team applied various treatments to swell, shrink, or stretch the cells. And they were able to observe the treatment’s impact on membrane tension, shape, and protrusion velocity.
The treatments only affected the cells’ shape and migration speed, not membrane tension. The results also showed that the more spherical a cell is, the faster it moves.
To interpret these unexpected findings, the scientists modeled a migrating cell as a liquid droplet spreading on a surface.
“It is well known that a droplet’s shape and, in particular, the contact angle that it makes with the surface are determined by the tension forces between the droplet, its environmental medium (eg, air or a different liquid), and the surface on which it moves,” Dr Gabella said.
Results of the modeling experiment suggested that the leading edge could be considered a triple interface between the substrate, membrane, and extracellular medium. And the contact angle between the membrane and the substrate determines the load on actin polymerization and, therefore, the protrusion rate.
“From this point of view, a more spherical cell means less load for actin filaments to overcome and, therefore, faster actin growth and migration,” said Alexander Verkhovsky, PhD, also of Ecole Polytechnique Fédérale de Lausanne.
In support of this idea, the scientists found the cells were sensitive to the surface characteristics, just as droplets would be, by slowing down or being pinned at ridges.
“The emphasis of many studies has been on discovering and characterizing individual cellular components,” Dr Verkhovsky said. “This is rooted in the common belief that a cell’s behavior is determined by intricate networks of genes and proteins.”
In contrast, this work shows that, despite their molecular complexity, cells can be described as physical objects. The findings point to a new relationship between a cell’s shape and its dynamics and may help us to understand how cell migration is guided by the cell’s 3D environment.
Scientists have discovered an unexpected link between the shape of a cell and its migration efficiency, and they’ve explained its physics using a model of a liquid droplet.
Cell migration is achieved through the movement of the cell’s membrane, which is powered by the action of a protein network inside the cell.
This interaction is affected by the cell’s overall shape, but exactly how this takes place has been unclear.
Research published in Current Biology provides some insight.
The first step in cell migration occurs when the cell extends its front edge—a process called protrusion. This is driven by the growth of actin filaments, which push the cell membrane from inside. At the same time, membrane tension controls protrusion by providing resistance and protecting the cell from over-extending.
But physical laws dictate that the shape of the cell membrane must play a role in the balance between force exerted by actin and the resisting membrane tension. This was not taken into account in previous studies, which used 2D models of migrating cells.
Now, Chiara Gabella, PhD, of Ecole Polytechnique Fédérale de Lausanne in Switzerland, and her colleagues have used a 3D model to better describe the relationship between cell protrusion, shape, and membrane tension.
The scientists developed a way to evaluate the 3D shape of migrating fish epidermal keratocytes by observing the cells in a chamber filled with a fluorescent solution.
The team applied various treatments to swell, shrink, or stretch the cells. And they were able to observe the treatment’s impact on membrane tension, shape, and protrusion velocity.
The treatments only affected the cells’ shape and migration speed, not membrane tension. The results also showed that the more spherical a cell is, the faster it moves.
To interpret these unexpected findings, the scientists modeled a migrating cell as a liquid droplet spreading on a surface.
“It is well known that a droplet’s shape and, in particular, the contact angle that it makes with the surface are determined by the tension forces between the droplet, its environmental medium (eg, air or a different liquid), and the surface on which it moves,” Dr Gabella said.
Results of the modeling experiment suggested that the leading edge could be considered a triple interface between the substrate, membrane, and extracellular medium. And the contact angle between the membrane and the substrate determines the load on actin polymerization and, therefore, the protrusion rate.
“From this point of view, a more spherical cell means less load for actin filaments to overcome and, therefore, faster actin growth and migration,” said Alexander Verkhovsky, PhD, also of Ecole Polytechnique Fédérale de Lausanne.
In support of this idea, the scientists found the cells were sensitive to the surface characteristics, just as droplets would be, by slowing down or being pinned at ridges.
“The emphasis of many studies has been on discovering and characterizing individual cellular components,” Dr Verkhovsky said. “This is rooted in the common belief that a cell’s behavior is determined by intricate networks of genes and proteins.”
In contrast, this work shows that, despite their molecular complexity, cells can be described as physical objects. The findings point to a new relationship between a cell’s shape and its dynamics and may help us to understand how cell migration is guided by the cell’s 3D environment.
Scientists have discovered an unexpected link between the shape of a cell and its migration efficiency, and they’ve explained its physics using a model of a liquid droplet.
Cell migration is achieved through the movement of the cell’s membrane, which is powered by the action of a protein network inside the cell.
This interaction is affected by the cell’s overall shape, but exactly how this takes place has been unclear.
Research published in Current Biology provides some insight.
The first step in cell migration occurs when the cell extends its front edge—a process called protrusion. This is driven by the growth of actin filaments, which push the cell membrane from inside. At the same time, membrane tension controls protrusion by providing resistance and protecting the cell from over-extending.
But physical laws dictate that the shape of the cell membrane must play a role in the balance between force exerted by actin and the resisting membrane tension. This was not taken into account in previous studies, which used 2D models of migrating cells.
Now, Chiara Gabella, PhD, of Ecole Polytechnique Fédérale de Lausanne in Switzerland, and her colleagues have used a 3D model to better describe the relationship between cell protrusion, shape, and membrane tension.
The scientists developed a way to evaluate the 3D shape of migrating fish epidermal keratocytes by observing the cells in a chamber filled with a fluorescent solution.
The team applied various treatments to swell, shrink, or stretch the cells. And they were able to observe the treatment’s impact on membrane tension, shape, and protrusion velocity.
The treatments only affected the cells’ shape and migration speed, not membrane tension. The results also showed that the more spherical a cell is, the faster it moves.
To interpret these unexpected findings, the scientists modeled a migrating cell as a liquid droplet spreading on a surface.
“It is well known that a droplet’s shape and, in particular, the contact angle that it makes with the surface are determined by the tension forces between the droplet, its environmental medium (eg, air or a different liquid), and the surface on which it moves,” Dr Gabella said.
Results of the modeling experiment suggested that the leading edge could be considered a triple interface between the substrate, membrane, and extracellular medium. And the contact angle between the membrane and the substrate determines the load on actin polymerization and, therefore, the protrusion rate.
“From this point of view, a more spherical cell means less load for actin filaments to overcome and, therefore, faster actin growth and migration,” said Alexander Verkhovsky, PhD, also of Ecole Polytechnique Fédérale de Lausanne.
In support of this idea, the scientists found the cells were sensitive to the surface characteristics, just as droplets would be, by slowing down or being pinned at ridges.
“The emphasis of many studies has been on discovering and characterizing individual cellular components,” Dr Verkhovsky said. “This is rooted in the common belief that a cell’s behavior is determined by intricate networks of genes and proteins.”
In contrast, this work shows that, despite their molecular complexity, cells can be described as physical objects. The findings point to a new relationship between a cell’s shape and its dynamics and may help us to understand how cell migration is guided by the cell’s 3D environment.
Combo can overcome resistance in MM
Credit: PNAS
A 2-drug combination can overcome Mcl-1-dependent treatment resistance in multiple myeloma (MM), preclinical research suggests.
The therapy consists of the Chk1 inhibitor CEP3891 and the MEK1/2 inhibitor PD184352.
Chk1 inhibitors prevent cells from arresting in stages of the cell cycle that facilitate DNA repair. And MEK inhibitors prevent cells from activating proteins that regulate DNA repair, while promoting the accumulation of pro-apoptotic proteins.
Researchers recounted their results with the 2 inhibitors in PLOS ONE.
The team noted that, although several drugs are effective against MM, the cancer cells can often survive treatment by increasing production of Mcl-1. This protein regulates processes that promote cell survival and has been implicated in resistance to bortezomib and other anti-myeloma drugs that were initially effective.
With their experiments, the researchers discovered that CEP3891 and PD184352 can reduce Mcl-1 expression and disrupt its interactions with other proteins to effectively kill MM cells.
“This research builds on our previous studies that showed exposing multiple myeloma and leukemia cells to Chk1 inhibitors activated a protective response through the Ras/MEK/ERK signaling pathway,” said Xin-Yan Pei, MD, PhD, of Virginia Commonwealth University and the Massey Cancer Center in Richmond.
“By combining a Chk1 inhibitor with a MEK inhibitor, we have developed one of only a limited number of strategies shown to circumvent therapeutic resistance caused by high expressions of Mcl-1.”
The team began this research by forcing overexpression of Mcl-1 in human MM cells. This caused the cells to become highly resistant to bortezomib, but it failed to protect them from CEP3891 and PD184352.
Furthermore, CEP3891 and PD184352 completely overcame resistance due to microenvironmental factors associated with increased expression of Mcl-1.
“Not only was the combination therapy effective against multiple myeloma cells, it notably did not harm normal bone marrow cells, raising the possibility of therapeutic selectivity,” said study author Steven Grant, MD, also of Virginia Commonwealth University and the Massey Cancer Center.
“We are hopeful that this research will lead to better therapies for multiple myeloma and help make current therapies more effective by overcoming resistance caused by Mcl-1.”
The researchers have started initial discussions with clinical investigators and drug manufacturers about a clinical trial testing a combination of Chk1 and MEK inhibitors in patients with refractory MM.
Credit: PNAS
A 2-drug combination can overcome Mcl-1-dependent treatment resistance in multiple myeloma (MM), preclinical research suggests.
The therapy consists of the Chk1 inhibitor CEP3891 and the MEK1/2 inhibitor PD184352.
Chk1 inhibitors prevent cells from arresting in stages of the cell cycle that facilitate DNA repair. And MEK inhibitors prevent cells from activating proteins that regulate DNA repair, while promoting the accumulation of pro-apoptotic proteins.
Researchers recounted their results with the 2 inhibitors in PLOS ONE.
The team noted that, although several drugs are effective against MM, the cancer cells can often survive treatment by increasing production of Mcl-1. This protein regulates processes that promote cell survival and has been implicated in resistance to bortezomib and other anti-myeloma drugs that were initially effective.
With their experiments, the researchers discovered that CEP3891 and PD184352 can reduce Mcl-1 expression and disrupt its interactions with other proteins to effectively kill MM cells.
“This research builds on our previous studies that showed exposing multiple myeloma and leukemia cells to Chk1 inhibitors activated a protective response through the Ras/MEK/ERK signaling pathway,” said Xin-Yan Pei, MD, PhD, of Virginia Commonwealth University and the Massey Cancer Center in Richmond.
“By combining a Chk1 inhibitor with a MEK inhibitor, we have developed one of only a limited number of strategies shown to circumvent therapeutic resistance caused by high expressions of Mcl-1.”
The team began this research by forcing overexpression of Mcl-1 in human MM cells. This caused the cells to become highly resistant to bortezomib, but it failed to protect them from CEP3891 and PD184352.
Furthermore, CEP3891 and PD184352 completely overcame resistance due to microenvironmental factors associated with increased expression of Mcl-1.
“Not only was the combination therapy effective against multiple myeloma cells, it notably did not harm normal bone marrow cells, raising the possibility of therapeutic selectivity,” said study author Steven Grant, MD, also of Virginia Commonwealth University and the Massey Cancer Center.
“We are hopeful that this research will lead to better therapies for multiple myeloma and help make current therapies more effective by overcoming resistance caused by Mcl-1.”
The researchers have started initial discussions with clinical investigators and drug manufacturers about a clinical trial testing a combination of Chk1 and MEK inhibitors in patients with refractory MM.
Credit: PNAS
A 2-drug combination can overcome Mcl-1-dependent treatment resistance in multiple myeloma (MM), preclinical research suggests.
The therapy consists of the Chk1 inhibitor CEP3891 and the MEK1/2 inhibitor PD184352.
Chk1 inhibitors prevent cells from arresting in stages of the cell cycle that facilitate DNA repair. And MEK inhibitors prevent cells from activating proteins that regulate DNA repair, while promoting the accumulation of pro-apoptotic proteins.
Researchers recounted their results with the 2 inhibitors in PLOS ONE.
The team noted that, although several drugs are effective against MM, the cancer cells can often survive treatment by increasing production of Mcl-1. This protein regulates processes that promote cell survival and has been implicated in resistance to bortezomib and other anti-myeloma drugs that were initially effective.
With their experiments, the researchers discovered that CEP3891 and PD184352 can reduce Mcl-1 expression and disrupt its interactions with other proteins to effectively kill MM cells.
“This research builds on our previous studies that showed exposing multiple myeloma and leukemia cells to Chk1 inhibitors activated a protective response through the Ras/MEK/ERK signaling pathway,” said Xin-Yan Pei, MD, PhD, of Virginia Commonwealth University and the Massey Cancer Center in Richmond.
“By combining a Chk1 inhibitor with a MEK inhibitor, we have developed one of only a limited number of strategies shown to circumvent therapeutic resistance caused by high expressions of Mcl-1.”
The team began this research by forcing overexpression of Mcl-1 in human MM cells. This caused the cells to become highly resistant to bortezomib, but it failed to protect them from CEP3891 and PD184352.
Furthermore, CEP3891 and PD184352 completely overcame resistance due to microenvironmental factors associated with increased expression of Mcl-1.
“Not only was the combination therapy effective against multiple myeloma cells, it notably did not harm normal bone marrow cells, raising the possibility of therapeutic selectivity,” said study author Steven Grant, MD, also of Virginia Commonwealth University and the Massey Cancer Center.
“We are hopeful that this research will lead to better therapies for multiple myeloma and help make current therapies more effective by overcoming resistance caused by Mcl-1.”
The researchers have started initial discussions with clinical investigators and drug manufacturers about a clinical trial testing a combination of Chk1 and MEK inhibitors in patients with refractory MM.
Letter to the Editor
We agree with Drs. Arora and Mahmud that emerging mobile health (mHealth) approaches to improving patient engagement will need to demonstrate their value to advance health and healthcare. The potential for mHealth to do this has been often described[1, 2] but, so far, rarely measured or demonstrated.
The technology costs of our tablet‐based intervention[3] were low: 2 iPads at $400 each. The real expense was for personnel: research assistants needed to teach patients how to use the technology effectively. In the future, we hope to shift device and software orientation to patient‐care assistants, nurses, or even digital assistants, nonmedical personnel who have technical expertise with the health‐related devices and software needed to engage with the electronic health record and educational materials. Thus, at least part of the challenge of cost‐effectiveness aside from improved outcomeswill be demonstrating eventual time savings for providers who no longer need to hand deliver or explain paper pamphlets or printouts, or shepherd patients through their digitally assisted education.
One day we may muse, what did we do before mHealth? as we might do now when using mobile technologies for nonhealth‐related tasks like getting directions or making a call. Indeed, who can remember the last time they routinely used a paper map or phonebook for these daily tasks? Our prescription for tablets is a step in that direction, but we will need to also reimagine patient education and related daily tasks at the hospital and system level to realize the potential of lower costs and higher quality care we can achieve using mHealth.[4]
- Can mobile health technologies transform health care? JAMA. 2013;310(22):2395–2396. , , .
- The effectiveness of mobile‐health technologies to improve health care service delivery processes: a systematic review and meta‐analysis. PLoS Med. 2013;10(1):e1001363. , , , et al.
- Tablet computers for hospitalized patients: a pilot study to improve inpatient engagement [published online ahead of print February 13, 2013]. J Hosp Med. doi: 10.1002/jhm.2169. , , , , .
- Patient engagement in the inpatient setting: a systematic review [published online ahead of print November 22, 2013]. J Am Med Inform Assoc. doi: 10.1136/amiajnl‐2013‐002141. , , , et al.
We agree with Drs. Arora and Mahmud that emerging mobile health (mHealth) approaches to improving patient engagement will need to demonstrate their value to advance health and healthcare. The potential for mHealth to do this has been often described[1, 2] but, so far, rarely measured or demonstrated.
The technology costs of our tablet‐based intervention[3] were low: 2 iPads at $400 each. The real expense was for personnel: research assistants needed to teach patients how to use the technology effectively. In the future, we hope to shift device and software orientation to patient‐care assistants, nurses, or even digital assistants, nonmedical personnel who have technical expertise with the health‐related devices and software needed to engage with the electronic health record and educational materials. Thus, at least part of the challenge of cost‐effectiveness aside from improved outcomeswill be demonstrating eventual time savings for providers who no longer need to hand deliver or explain paper pamphlets or printouts, or shepherd patients through their digitally assisted education.
One day we may muse, what did we do before mHealth? as we might do now when using mobile technologies for nonhealth‐related tasks like getting directions or making a call. Indeed, who can remember the last time they routinely used a paper map or phonebook for these daily tasks? Our prescription for tablets is a step in that direction, but we will need to also reimagine patient education and related daily tasks at the hospital and system level to realize the potential of lower costs and higher quality care we can achieve using mHealth.[4]
We agree with Drs. Arora and Mahmud that emerging mobile health (mHealth) approaches to improving patient engagement will need to demonstrate their value to advance health and healthcare. The potential for mHealth to do this has been often described[1, 2] but, so far, rarely measured or demonstrated.
The technology costs of our tablet‐based intervention[3] were low: 2 iPads at $400 each. The real expense was for personnel: research assistants needed to teach patients how to use the technology effectively. In the future, we hope to shift device and software orientation to patient‐care assistants, nurses, or even digital assistants, nonmedical personnel who have technical expertise with the health‐related devices and software needed to engage with the electronic health record and educational materials. Thus, at least part of the challenge of cost‐effectiveness aside from improved outcomeswill be demonstrating eventual time savings for providers who no longer need to hand deliver or explain paper pamphlets or printouts, or shepherd patients through their digitally assisted education.
One day we may muse, what did we do before mHealth? as we might do now when using mobile technologies for nonhealth‐related tasks like getting directions or making a call. Indeed, who can remember the last time they routinely used a paper map or phonebook for these daily tasks? Our prescription for tablets is a step in that direction, but we will need to also reimagine patient education and related daily tasks at the hospital and system level to realize the potential of lower costs and higher quality care we can achieve using mHealth.[4]
- Can mobile health technologies transform health care? JAMA. 2013;310(22):2395–2396. , , .
- The effectiveness of mobile‐health technologies to improve health care service delivery processes: a systematic review and meta‐analysis. PLoS Med. 2013;10(1):e1001363. , , , et al.
- Tablet computers for hospitalized patients: a pilot study to improve inpatient engagement [published online ahead of print February 13, 2013]. J Hosp Med. doi: 10.1002/jhm.2169. , , , , .
- Patient engagement in the inpatient setting: a systematic review [published online ahead of print November 22, 2013]. J Am Med Inform Assoc. doi: 10.1136/amiajnl‐2013‐002141. , , , et al.
- Can mobile health technologies transform health care? JAMA. 2013;310(22):2395–2396. , , .
- The effectiveness of mobile‐health technologies to improve health care service delivery processes: a systematic review and meta‐analysis. PLoS Med. 2013;10(1):e1001363. , , , et al.
- Tablet computers for hospitalized patients: a pilot study to improve inpatient engagement [published online ahead of print February 13, 2013]. J Hosp Med. doi: 10.1002/jhm.2169. , , , , .
- Patient engagement in the inpatient setting: a systematic review [published online ahead of print November 22, 2013]. J Am Med Inform Assoc. doi: 10.1136/amiajnl‐2013‐002141. , , , et al.
Hospital Unit‐Based Leadership Models
Hospital‐based care has become more complex over time. Patients are sicker, with more chronic comorbid conditions requiring greater collaboration to provide coordinated patient care.[1, 2] Care coordination requires an interdisciplinary approach during hospitalization and especially during transitions of care.[3, 4] In addition, hospitals are tasked with managing and improving clinical workflow efficiencies, and implementing electronic health records (EHR)[5] that require healthcare professionals to learn new systems of care and technology. Payment models have also started to shift toward an incentive and penalty‐based structure in the form of value‐based purchasing, readmission penalties, hospital‐acquired conditions, and meaningful use.[4, 6]
In response to these pressures, hospitals are searching for ways to reliably deliver quality care that is safe, effective, patient centered, timely, efficient, and equitable.[7] Previous efforts to improve quality in the general medical inpatient setting have included redesign of the clinical work environment and new workflows through the use of checklists and whiteboards to enhance communication, patient‐centered bedside rounds, standardized protocols and handovers, and integrated clinical decision support using health information technology.[8, 9, 10, 11, 12, 13] Although each of these care coordination activities has potential value, integrating them at the unit level often remains a challenge. Some hospitals have addressed this challenge by establishing and supporting a unit‐based leadership model, where a medical director and nurse manager work together to assess and improve the quality, safety, efficiency, and patient experience‐based mission of the organization.[14, 15] However, there are few descriptions of this leadership model in the current literature. Herein, we present the unit‐based leadership model that has been developed and implemented at 6 hospitals.
MODELS OF UNIT‐BASED LEADERSHIP
The unit‐based leadership model is grounded on the idea that culture and clinical care are products of frontline structure, process, and relationships, and that leaders at the site of care can have the greatest influence on the local work environment.[16, 17] The objective is to influence care and culture at the bedside and the unit, where care is delivered and where alignment with organizational vision and mission must occur. The concept of the inpatient unit medical director is not new, and hospitals in the past have recruited physician leaders to become clinical champions for quality improvement and help establish a collaborative work environment for physicians and unit‐based staff.[18, 19, 20, 21, 22] These studies report on the challenges and benefits of incorporating a medical director to inpatient psychiatry or general care units, but do not provide specific details about the recruitment and responsibilities for unit‐based dyad partnerships, which are critical factors for success on multidisciplinary inpatient care units.
There are several logistical matters to consider when instituting a unit‐based leadership model. These include the composition of the leadership team, selection process of the leaders, the presence of trainees and permanent faculty, and whether the units are able to geographically cohort patients. Other considerations include a clear role description with established shared goals and expectations, and a compensation model that includes effort and incentives. In addition, there should be a clearly established reporting structure to senior leadership, and the unit leaders should be given opportunities for professional growth and development. Table 1 provides a summary overview of 6 hospitals' experiences to date.
Structure | Hospital of the University of Pennsylvania | Northwestern Memorial Hospital | Emory University Hospital | University of Michigan Health System | Christiana Care Health System | St. Joseph Mercy Health System/Integrated Health Associates |
---|---|---|---|---|---|---|
| ||||||
Description of hospital(s) | Academic medical center, 784 beds, 40,000 annual admissions | Academic medical center, 897 beds, 53,000 annual admissions | Academic medical center, 579 beds, 24,000 annual admissions | Academic medical center, 839 beds, 45,000 annual admissions | Independent academic medical center, 1,100 beds, 53,000 annual admissions | Tertiary community hospital that is part of a larger health care system (Trinity Health), 579 beds, 33,000 annual admissions |
Unit leadership model | Triad of medical director, nurse manager, and quality improvement specialist/project manager | Dyad of medical director and nurse manager | Dyad of medical director and nurse manager | Dyad of medical director and nurse manager | Dyad of medical director and nurse manager | Dyad of medical director and nurse manager |
Percent effort time supported for unit medical director | 10% | 17% | 10% | 20% | 20% | 10% |
Incentives built into unit leaders' performance in outcomes metrics | No | Yes | No | No | No | Yes |
Professional development/leadership training | Quality improvement method: PDSA, Six Sigma, Lean Healthcare | Quality improvement method: Six Sigma | Situational leadership training with 1:1 mentoring | Quality improvement method: Lean Healthcare, service excellence program | Quality Improvement method: Six Sigma, Lean Healthcare | Quality improvement method: Six Sigma |
Additional leadership development through Penn Medicine Leadership Academy and Wharton Executive Education | Additional leadership development through Northwestern's professional development center and simulation training center | Conflict resolution skill development | Attend patient and Family Centered Care conference | Additional leadership development through Christiana Care Learning Institute | Attend educational course on Crucial Conversations | |
Personality profile with coaching | Additional leadership development through University of Michigan Health System's human resources group | |||||
Outcomes metrics monitored | Patient satisfaction | Patient satisfaction | Patient satisfaction | Patient satisfaction | Patient satisfaction | Patient satisfaction |
Efficiency of multidisciplinary rounds | Teamwork climate (survey) | Teamwork and implementation of structured interdisciplinary bedside rounds | Multidisciplinary rounds | Interdisciplinary rounds | Participation in interdisciplinary rounds | |
RNMD work environment surveys | Adverse events | Unit‐based patient safety culture survey | Patient‐centered, bedside rounds | Readmission rates | ||
Hospital‐acquired conditions (CAUTI, CLABSI, VAP, DVT, pressure ulcers) | Hospital‐acquired conditions (fall rates, pressure ulcers | Hospital‐acquired conditions (CAUTI, CLABSI, fall rates, pressure ulcers) | Hospital‐acquired conditions (CAUTI) | Hospital‐acquired conditions (fall rates, pressure ulcers) | Core measures | |
Readmission rates | Readmission rates | Mortality | Readmission rates | Readmission rates | Medication reconciliation | |
Core measures, patient safety indicators | Core measures | Length of stay | DVT prophylaxis | Hand hygiene | Discharge by 11 am | |
Mortality (observed to expected, transfer, inpatient) | Hand hygiene | Glycemic control | Meeting attendance | Length of stay | Use of patient teach‐back | |
Medication reconciliation | Restraint use | Communication with PCPs | ||||
Home care, hospice, post‐acute care referral rates | ||||||
Organizational leadership structure support for clinical unit partnership program | CMO, CNO, vice president of quality/patient safety, directors of medical and surgical nursing | Associate chair of medicine, director of medicine nursing; all medical directors are members of the department of medicine quality management committee | CMO, CNO, CEO, CQO | CMO, CNO | All teams report to and are supported by 3 overarching, system‐wide committees: (1) safety first, (2) think of yourself as a patient, (3) clinical excellence. Those committees, in turn, report up to the senior management quality/safety coordinating council. | Director of hospitalist program (reports to CMO); nursing director of acute care (reports to CNO) |
DISCUSSION
In reviewing our 6 organization's collective experiences, we identified several common themes and some notable differences across sites. The core of the leadership team was primarily composed of the medical director and nurse manager on the unit. Across all 6 organizations, medical directors had a portion of their effort supported for their leadership work on the unit. Leadership development training was provided at all of our sites, with particular emphasis on quality improvement (QI) methods such as Six‐Sigma, Lean, or Plan, Do, Study, Act (PDSA). Additional leadership development sessions were provided through the organization's human resources or affiliated university. Common outcome measures of interest include patient satisfaction, interdisciplinary practice, and collaboration on the unit, and some hospital‐acquired condition measures. Last, there is a direct reporting relationship to a chief or senior nurse or physician leader within each organization. These commonalities and variances are further detailed below.
Establishing the Unit‐Based Leadership Model
The composition of the unit‐based leadership model in our 6 organizations is predominantly a dyad partnership of medical directors and nurse managers. Although informal physician‐nurse collaborative practices have likely been in existence at many hospitals, formalizing this dyad partnership is an important step to fostering collaborative efforts to improve quality of care. It is also essential for hospital leadership to clearly articulate the need for this unit‐based leadership model. Whether the motivation for change is from a previously untenable practice environment, or part of an ongoing improvement program, the model should be presented in a manner that supports the organization's commitment to improve collaborative practices for better patient care. One of our 6 hospitals initiated this leadership model based on troubling relationships between nurses and physicians on some of their inpatient care units, which threatened to stall the organization's Magnet application. Implementation of the leadership model at the unit level yielded improvements in nursephysician interactions, patient satisfaction, and staff turnover.[15, 23] Another of the hospitals first evaluated why a previous attempt at this model did not deliver the intended outcomes, and redesigned the model based on its analysis.[14]
Across all of the organizations featured here, a common driver behind the adoption of the unit‐based leadership model was to bridge the divide between physician services and nursing and other allied health providers. We found that many of the physicians routinely had patients on multiple units, limiting the quantity and quality of collaborative practices between unit‐based staff and physician teams. The unit‐based dyad leaders are ideally positioned to build and foster a culture of collaboration, and our organizations have been inclusive to ensure the participation of a multidisciplinary group of providers, including representatives from pharmacy, environmental services, physical therapy, respiratory therapy, social work, case management, and nutrition at leadership meetings or in daily patient‐care discussions. In addition, 2 of the organizations have added quality improvement specialist/project managers to their teams to support the physiciannurse manager leaders on the unit.
Selection Process and Professional Development
The traditional approach to hiring a physician leader or a nurse manager has been an isolated process of drafting a job description for each position and hiring within their respective departments. For the dyad partnership to be successful, there should be established goals and expectations that require shared responsibilities between the 2 partners, which should guide the selection of these leaders. Other leadership attributes and essential character traits that should be modeled by the unit‐based leaders include good communication skills, respect among coworkers, and a collaborative approach to decision making and action. In addition, both physician leaders and nurse managers in these roles should have the ability to take a system's view, recognizing that within the complex network of healthcare providers and processes on their unit, these elements interact with each other, which lead to the outcomes achieved on their units.[24, 25] Table 2 lists some general shared responsibilities, highlighting specific activities that can be used to achieve the established outcomes. As the unit's dyad leadership works together to address these shared responsibilities, they should keep their sights focused on the overall strategic goals of the healthcare organization. Bohmer has defined 4 habits of the high‐value healthcare organization that in turn can be reflected through the inpatient unit leadership model to capture these activities at the local level: (1) planning care for specific patient populations, (2) microsystem design, (3) measurement and oversight, and (4) self‐study.[26] In determining specific shared responsibilities for each dyad partner, it is important for these leaders to understand the clinical microsystem of their unit such as their patient population, interdisciplinary care team, approach to process improvement, and performance patterns over time.[27]
General Shared Responsibilities of Physician and Nurse Unit Directors | Examples of Specific Activities |
---|---|
| |
Serve as management partners to enhance culture of the unit | Co‐craft and deliver consistent leadership message |
Co‐establish and enforce unit processes and protocols | |
Co‐lead recruitment and retention efforts | |
Co‐orient trainees and faculty rotating through unit | |
Co‐educate on the management of common medical and surgical conditions | |
Facilitate interstaff conflict resolution sessions | |
Regular leadership meetings | |
Actively manage unit processes and outcomes | Quality: improve core quality measure performance |
Safety: improve culture of patient safety within the unit as measured by surveys and incident reporting systems | |
Efficiency: reduce unnecessary length of stay and variability in resource use | |
Patient experience: focus on improving patient‐family experience with targeted outcomes in patient experience metrics (eg, HCAHPS) | |
Education: develop trainee and staff clinical and teamwork competencies | |
Continuous process improvement initiatives (eg, PDSA cycles) | Improve the discharge transitions process, tailoring the process to each individual patient's identified risk factors |
Focus improvement efforts on reduction in specific hospital acquired conditions such as CAUTI, VTE, CLABSI, pressure ulcers, falls | |
Measure, analyze, reassess, and improve in all described areas of shared responsibilities | |
Perform unit level chart reviews to evaluate readmissions and LOS and identify improvement opportunities |
In our collective experience, the dyad leaders bring passion and commitment to improving care; however, many (the medical directors in particular) have minimal prior formal training in leadership, quality improvement, or hospital management. Recognizing that unit leaders require specialized knowledge and skills, each of our organizations has enrolled unit medical directors and nurse managers in leadership development courses or educational programs. Many healthcare organizations have become more grounded in a QI methodology including Six‐Sigma, Lean Healthcare, PDSA, and other scientifically based methods, and the unit‐based leaders should receive advanced training in the preferred methods of their institution. Additional training in quality improvement, patient safety, and physician leadership can also be obtained through supplemental coursework specifically designed to train hospital leaders, with some programs leading to a certification or additional credentials.[28]
Beyond such formal educational opportunities, hospitals should not overlook the opportunity to learn from and share experiences with the other dyad leadership units within the hospital. One of the organizations described here holds monthly meetings with all of the unit dyad leaders, and 2 other organizations conduct quarterly meetings to share experiences and best practices related to specific improvement initiatives in a learning network model. Those units with more experience in specific initiatives are asked to share their lessons learned with others, as well as support each other in their efforts to collectively meet the strategic goals of the hospital.
Time and Organizational Support
In addition to leadership development, hospitals and the clinical department leadership need to support the medical directors with dedicated time away from their usual clinical duties. Some organizations in this report are providing up to 20% effort for the medical director's unit‐based leadership work; however, there is some variation in practice with regard to physician effort across sites. The University of Pennsylvania has a smaller effort support at 10%; however, some of that effort differential may be offset through the allocation of the quality improvement specialist/project manager assigned to work with the medical director and nurse manager dyad. St. Joseph Mercy Hospital also has a lower allocation, as there is additional financial compensation for the role that is at risk and not included in this 10% allocation.
It is also important to assure that the medical directors have institutional support to carry out their work in partnership with their nursing leadership. The 6 health systems described here report that although most of the physicians have appointments within a physician group or clinical department, there is hospital leadership oversight from a chief medical, nursing, or operating officer. This organizational structure may be an important aspect of the model as the unit‐based leaders seek to align their efforts with that of the hospital. Further, this form of organizational oversight can ensure that the unit leaders will receive timely and essential unit‐ and hospital‐based performance measures to manage local improvement efforts. These measures may include some components of patient experiences as reported in the Hospital Consumer Assessment of Healthcare Providers and Systems survey, readmission rates, hospital‐acquired condition rates, length of stay, observed to expected mortality rates, and results of staff satisfaction and safety culture surveys. As highlighted by several studies and commentaries, our collective experiences also identified interdisciplinary teamwork, collaboration, and communication as desirable outcome measures through the unit‐based leadership structure.[21, 22, 24, 29, 30] The medical director and nurse manager dyads can prioritize their improvement efforts based on the data provided to them, and mobilize the appropriate group of multidisciplinary practitioners and support staff on the unit.
OTHER CONSIDERATIONS
Other infrastructure variables that may increase the effectiveness of the unit leadership dyad include unit‐based clinical services (geographic localization), engaging the frontline team members in the design and implementation of change innovations, a commitment to patient and family centered practices on the unit, and enhancing clinical workflow through the support of EHR functions such as concurrent documentation and provider order entry. Geographic localization, placing the fewest possible clinical service providers on the unit to work alongside unit‐based staff, allows for a cohesive interdisciplinary unit‐based team to develop under the dyad leadership, and has been shown to improve communication practices.[9, 31] Beyond geographic localization of patients, it is critical to ensure team members are committed to the changes in workflow by directly involving them through the design and implementation of new models of care taking place on the unit. This commitment starts from the top senior nurse and physician leaders in the organization, and extends to the unit‐based dyad partners, and down to each individual interdisciplinary team member on the unit.[1] Thus, it is critical to clarify roles and responsibilities and how team members on the unit will interact with each other. For some situations, conflict management training will be helpful to the unit‐based leaders to resolve issues. To appreciate potential barriers to successful rollout of this unit leadership model, a phased implementation of pilot units, followed by successive waves, should be considered. Many of the units that instituted unit‐based interdisciplinary team rounds solicited and implemented direct feedback from frontline team members in efforts to improve communication and be more patient centered. Conversely, there are also likely to be situations where the unit‐based leaders will be confronted with hindrances to their unit‐based collaborative improvement efforts. To help prepare the dyad leaders, many of our unit‐based leaders have received specific training on how to coach and conduct difficult conversations with individuals who have performance gaps or are perceived to be hindering the progress of the unit's work. These crucial negotiation skills are not innate among most managers and should be explicitly provided to new leaders across organizations.
The goals and merits of patient‐ and family‐centered care (PFCC) have been well described.[32, 33, 34] Organizational support to teach and disseminate PFCC practices throughout all settings of care may help the leadership dyads implement rounding strategies that engage all staff, patients, and family members throughout the hospital course and during the transitions out of the hospital.
Clinical workflow has become heavily dependent on the EHR systems. For those organizations that have yet to adopt a particular EHR system, the leadership dyads should be involved throughout the EHR design process to help ensure that the technological solutions will be built to assist the clinical workflow, and once the system has been built, the leadership dyad should monitor and enhance the interface between workflow and EHR system so that it can support the creation and advancement of interdisciplinary plans of care on the unit.
CONCLUSION
The care of the hospitalized patient has become more complex over time. Interdisciplinary teamwork needs to be improved at the unit level to achieve the strategic goals of the hospital. Although quality improvement is an organizational goal, change takes place locally. Physician leaders, in partnership with nurse managers, are needed now more than ever to take on this task to improve the hospital‐care experience for patients by functioning as the primary effector arms for changing the landscape of hospital‐based care. We have described characteristics of unit‐based leadership programs adopted across 6 organizations. Hospitalists with clinical experience as the principal providers of inpatient‐based care and quality improvement experience and training, have been key participants in the development and implementation of the local leadership models in each of these hospital systems. We hope the comparison of the various models featured in this article serves as a valuable reference to hospitals and healthcare organizations who are contemplating the incorporation of this model into their strategic plan.
- Organizational predictors of coordination in inpatient medicine [published online ahead of print February 26, 2014]. Health Care Manage Rev. doi: 10.1097/HMR.0000000000000004. , , , et al.
- Trends in case‐mix in the medicare population. Paper presented at: American Hospital Association, Federation of American Hospitals, Association of American Medical Colleges; http://www.aha.org/content/00‐10/100715‐CMItrends.pdf. July 15, 2010. .
- A requirement to reduce readmissions: take care of the patient, not just the disease. JAMA. 2013;309(4):394–396. .
- Value‐based purchasing—national programs to move from volume to value. N Engl J Med. 2012;367(4):292–295. , .
- Medicare and Medicaid programs; electronic health record incentive program. Final rule. Fed Regist. 2010;75(144):44313–44588.
- The Center for Medicare and Medicaid innovation's blueprint for rapid‐cycle evaluation of new care and payment models. Health Aff (Millwood). 2013;32(4):807–812. .
- Institute of Medicine. Crossing the Quality Chasm: A New Health System for the 21st Century. Washington, DC: National Academies Press; 2001.
- Improving teamwork: impact of structured interdisciplinary rounds on a medical teaching unit. J Gen Intern Med. 2010;25(8):826–832. , , , , , .
- Impact of localizing physicians to hospital units on nurse‐physician communication and agreement on the plan of care. J Gen Intern Med. 2009;24(11):1223–1227. , , , et al.
- A review on systematic reviews of health information system studies. J Am Med Inform Assoc. 2010;17(6):637–645. , , , .
- Patient whiteboards as a communication tool in the hospital setting: a survey of practices and recommendations. J Hosp Med. Apr 2010;5(4):234–239. , , , , .
- Development of a checklist for documenting team and collaborative behaviors during multidisciplinary bedside rounds. J Nurs Adm. 2013;43(5):280–285. , , .
- Assessment of teamwork during structured interdisciplinary rounds on medical units. J Hosp Med. 2012;7(9):679–683. , , , , .
- Leadership at the front line: a clinical partnership model on general care inpatient units. Am J Med Qual. 2012;27(2):106–111. , , , et al.
- AHRQ health care innovations exchange: improvement projects led by unit‐based teams of nurse, physician, and quality leaders reduce infections, lower costs, improve patient satisfaction, and nurse‐physician communication. Available at: http://www.innovations.ahrq.gov/content.aspx?id=2719. Published April 14, 2010. Accessed November 26, 2011. , .
- Microsystems in health care: part 8. Developing people and improving work life: what front‐line staff told us. Jt Comm J Qual Saf. 2003;29(10):512–522. , , , , , .
- Microsystems in health care: part 5. How leaders are leading. Jt Comm J Qual Saf. 2003;29(6):297–308. , , , et al.
- The academic dilemma of the inpatient unit director. Am J Psychiatry. 1989;146(1):73–76. , , .
- Improving and sustaining core measure performance through effective accountability of clinical microsystems in an academic medical center. Jt Comm J Qual Patient Saf. 2010;36(9):387–398. , , , , .
- Physician leadership and quality improvement in the acute child and adolescent psychiatric care setting. Child Adolesc Psychiatr Clin N Am. 2010;19(1):1–19; table of contents. , , .
- Effect of a multidisciplinary intervention on communication and collaboration among physicians and nurses. Am J Crit Care. 2005;14(1):71–77. , , , .
- Nurse‐physician leadership: insights into interprofessional collaboration. J Nurs Adm. 2013;43(12):653–659. , .
- The Advisory Board. University of Pennsylvania Health System pilots unit clinical leadership model to spur quality gains. Nurs Exec Watch. 2008;9(2):4–6.
- Physicians as leaders in improving health care: a new series in Annals of Internal Medicine. Ann Intern Med. 1998;128(4):289–292. , .
- Understanding medical systems. Ann Intern Med. 1998;128(4):293–298. .
- The four habits of high‐value health care organizations. N Engl J Med. 2011;365(22):2045–2047. .
- Microsystems in health care: Part 1. Learning from high‐performing front‐line clinical units. Jt Comm J Qual Improv. 2002;28(9):472–493. , , , et al.
- The quality and safety educators academy: fulfilling an unmet need for faculty development. Am J Med Qual. 2014;29(1):5–12. , , , et al.
- Cooperation: the foundation of improvement. Ann Intern Med. 1998;128(12 pt 1):1004–1009. , , , .
- Ten principles of good interdisciplinary team work. Hum Resour Health 2013;11(1):19. , , , , , .
- Impact of localizing general medical teams to a single nursing unit. J Hosp Med. 2012;7(7):551–556. , , , et al.
- Integrating patient‐ and family‐centered care with health policy: four proposed policy approaches. Qual Manag Health Care. 2013;22(2):137–145. , , , .
- Incorporating patient‐ and family‐centered care into resident education: approaches, benefits, and challenges. J Grad Med Educ. 2011;3(2):272–278. , , .
- Smith M, Saunders R, Stuckhardt L, McGinnis JM, eds. Best Care at Lower Cost: The Path to Continuously Learning Health Care in America. Washington, DC: National Academies Press; 2012.
Hospital‐based care has become more complex over time. Patients are sicker, with more chronic comorbid conditions requiring greater collaboration to provide coordinated patient care.[1, 2] Care coordination requires an interdisciplinary approach during hospitalization and especially during transitions of care.[3, 4] In addition, hospitals are tasked with managing and improving clinical workflow efficiencies, and implementing electronic health records (EHR)[5] that require healthcare professionals to learn new systems of care and technology. Payment models have also started to shift toward an incentive and penalty‐based structure in the form of value‐based purchasing, readmission penalties, hospital‐acquired conditions, and meaningful use.[4, 6]
In response to these pressures, hospitals are searching for ways to reliably deliver quality care that is safe, effective, patient centered, timely, efficient, and equitable.[7] Previous efforts to improve quality in the general medical inpatient setting have included redesign of the clinical work environment and new workflows through the use of checklists and whiteboards to enhance communication, patient‐centered bedside rounds, standardized protocols and handovers, and integrated clinical decision support using health information technology.[8, 9, 10, 11, 12, 13] Although each of these care coordination activities has potential value, integrating them at the unit level often remains a challenge. Some hospitals have addressed this challenge by establishing and supporting a unit‐based leadership model, where a medical director and nurse manager work together to assess and improve the quality, safety, efficiency, and patient experience‐based mission of the organization.[14, 15] However, there are few descriptions of this leadership model in the current literature. Herein, we present the unit‐based leadership model that has been developed and implemented at 6 hospitals.
MODELS OF UNIT‐BASED LEADERSHIP
The unit‐based leadership model is grounded on the idea that culture and clinical care are products of frontline structure, process, and relationships, and that leaders at the site of care can have the greatest influence on the local work environment.[16, 17] The objective is to influence care and culture at the bedside and the unit, where care is delivered and where alignment with organizational vision and mission must occur. The concept of the inpatient unit medical director is not new, and hospitals in the past have recruited physician leaders to become clinical champions for quality improvement and help establish a collaborative work environment for physicians and unit‐based staff.[18, 19, 20, 21, 22] These studies report on the challenges and benefits of incorporating a medical director to inpatient psychiatry or general care units, but do not provide specific details about the recruitment and responsibilities for unit‐based dyad partnerships, which are critical factors for success on multidisciplinary inpatient care units.
There are several logistical matters to consider when instituting a unit‐based leadership model. These include the composition of the leadership team, selection process of the leaders, the presence of trainees and permanent faculty, and whether the units are able to geographically cohort patients. Other considerations include a clear role description with established shared goals and expectations, and a compensation model that includes effort and incentives. In addition, there should be a clearly established reporting structure to senior leadership, and the unit leaders should be given opportunities for professional growth and development. Table 1 provides a summary overview of 6 hospitals' experiences to date.
Structure | Hospital of the University of Pennsylvania | Northwestern Memorial Hospital | Emory University Hospital | University of Michigan Health System | Christiana Care Health System | St. Joseph Mercy Health System/Integrated Health Associates |
---|---|---|---|---|---|---|
| ||||||
Description of hospital(s) | Academic medical center, 784 beds, 40,000 annual admissions | Academic medical center, 897 beds, 53,000 annual admissions | Academic medical center, 579 beds, 24,000 annual admissions | Academic medical center, 839 beds, 45,000 annual admissions | Independent academic medical center, 1,100 beds, 53,000 annual admissions | Tertiary community hospital that is part of a larger health care system (Trinity Health), 579 beds, 33,000 annual admissions |
Unit leadership model | Triad of medical director, nurse manager, and quality improvement specialist/project manager | Dyad of medical director and nurse manager | Dyad of medical director and nurse manager | Dyad of medical director and nurse manager | Dyad of medical director and nurse manager | Dyad of medical director and nurse manager |
Percent effort time supported for unit medical director | 10% | 17% | 10% | 20% | 20% | 10% |
Incentives built into unit leaders' performance in outcomes metrics | No | Yes | No | No | No | Yes |
Professional development/leadership training | Quality improvement method: PDSA, Six Sigma, Lean Healthcare | Quality improvement method: Six Sigma | Situational leadership training with 1:1 mentoring | Quality improvement method: Lean Healthcare, service excellence program | Quality Improvement method: Six Sigma, Lean Healthcare | Quality improvement method: Six Sigma |
Additional leadership development through Penn Medicine Leadership Academy and Wharton Executive Education | Additional leadership development through Northwestern's professional development center and simulation training center | Conflict resolution skill development | Attend patient and Family Centered Care conference | Additional leadership development through Christiana Care Learning Institute | Attend educational course on Crucial Conversations | |
Personality profile with coaching | Additional leadership development through University of Michigan Health System's human resources group | |||||
Outcomes metrics monitored | Patient satisfaction | Patient satisfaction | Patient satisfaction | Patient satisfaction | Patient satisfaction | Patient satisfaction |
Efficiency of multidisciplinary rounds | Teamwork climate (survey) | Teamwork and implementation of structured interdisciplinary bedside rounds | Multidisciplinary rounds | Interdisciplinary rounds | Participation in interdisciplinary rounds | |
RNMD work environment surveys | Adverse events | Unit‐based patient safety culture survey | Patient‐centered, bedside rounds | Readmission rates | ||
Hospital‐acquired conditions (CAUTI, CLABSI, VAP, DVT, pressure ulcers) | Hospital‐acquired conditions (fall rates, pressure ulcers | Hospital‐acquired conditions (CAUTI, CLABSI, fall rates, pressure ulcers) | Hospital‐acquired conditions (CAUTI) | Hospital‐acquired conditions (fall rates, pressure ulcers) | Core measures | |
Readmission rates | Readmission rates | Mortality | Readmission rates | Readmission rates | Medication reconciliation | |
Core measures, patient safety indicators | Core measures | Length of stay | DVT prophylaxis | Hand hygiene | Discharge by 11 am | |
Mortality (observed to expected, transfer, inpatient) | Hand hygiene | Glycemic control | Meeting attendance | Length of stay | Use of patient teach‐back | |
Medication reconciliation | Restraint use | Communication with PCPs | ||||
Home care, hospice, post‐acute care referral rates | ||||||
Organizational leadership structure support for clinical unit partnership program | CMO, CNO, vice president of quality/patient safety, directors of medical and surgical nursing | Associate chair of medicine, director of medicine nursing; all medical directors are members of the department of medicine quality management committee | CMO, CNO, CEO, CQO | CMO, CNO | All teams report to and are supported by 3 overarching, system‐wide committees: (1) safety first, (2) think of yourself as a patient, (3) clinical excellence. Those committees, in turn, report up to the senior management quality/safety coordinating council. | Director of hospitalist program (reports to CMO); nursing director of acute care (reports to CNO) |
DISCUSSION
In reviewing our 6 organization's collective experiences, we identified several common themes and some notable differences across sites. The core of the leadership team was primarily composed of the medical director and nurse manager on the unit. Across all 6 organizations, medical directors had a portion of their effort supported for their leadership work on the unit. Leadership development training was provided at all of our sites, with particular emphasis on quality improvement (QI) methods such as Six‐Sigma, Lean, or Plan, Do, Study, Act (PDSA). Additional leadership development sessions were provided through the organization's human resources or affiliated university. Common outcome measures of interest include patient satisfaction, interdisciplinary practice, and collaboration on the unit, and some hospital‐acquired condition measures. Last, there is a direct reporting relationship to a chief or senior nurse or physician leader within each organization. These commonalities and variances are further detailed below.
Establishing the Unit‐Based Leadership Model
The composition of the unit‐based leadership model in our 6 organizations is predominantly a dyad partnership of medical directors and nurse managers. Although informal physician‐nurse collaborative practices have likely been in existence at many hospitals, formalizing this dyad partnership is an important step to fostering collaborative efforts to improve quality of care. It is also essential for hospital leadership to clearly articulate the need for this unit‐based leadership model. Whether the motivation for change is from a previously untenable practice environment, or part of an ongoing improvement program, the model should be presented in a manner that supports the organization's commitment to improve collaborative practices for better patient care. One of our 6 hospitals initiated this leadership model based on troubling relationships between nurses and physicians on some of their inpatient care units, which threatened to stall the organization's Magnet application. Implementation of the leadership model at the unit level yielded improvements in nursephysician interactions, patient satisfaction, and staff turnover.[15, 23] Another of the hospitals first evaluated why a previous attempt at this model did not deliver the intended outcomes, and redesigned the model based on its analysis.[14]
Across all of the organizations featured here, a common driver behind the adoption of the unit‐based leadership model was to bridge the divide between physician services and nursing and other allied health providers. We found that many of the physicians routinely had patients on multiple units, limiting the quantity and quality of collaborative practices between unit‐based staff and physician teams. The unit‐based dyad leaders are ideally positioned to build and foster a culture of collaboration, and our organizations have been inclusive to ensure the participation of a multidisciplinary group of providers, including representatives from pharmacy, environmental services, physical therapy, respiratory therapy, social work, case management, and nutrition at leadership meetings or in daily patient‐care discussions. In addition, 2 of the organizations have added quality improvement specialist/project managers to their teams to support the physiciannurse manager leaders on the unit.
Selection Process and Professional Development
The traditional approach to hiring a physician leader or a nurse manager has been an isolated process of drafting a job description for each position and hiring within their respective departments. For the dyad partnership to be successful, there should be established goals and expectations that require shared responsibilities between the 2 partners, which should guide the selection of these leaders. Other leadership attributes and essential character traits that should be modeled by the unit‐based leaders include good communication skills, respect among coworkers, and a collaborative approach to decision making and action. In addition, both physician leaders and nurse managers in these roles should have the ability to take a system's view, recognizing that within the complex network of healthcare providers and processes on their unit, these elements interact with each other, which lead to the outcomes achieved on their units.[24, 25] Table 2 lists some general shared responsibilities, highlighting specific activities that can be used to achieve the established outcomes. As the unit's dyad leadership works together to address these shared responsibilities, they should keep their sights focused on the overall strategic goals of the healthcare organization. Bohmer has defined 4 habits of the high‐value healthcare organization that in turn can be reflected through the inpatient unit leadership model to capture these activities at the local level: (1) planning care for specific patient populations, (2) microsystem design, (3) measurement and oversight, and (4) self‐study.[26] In determining specific shared responsibilities for each dyad partner, it is important for these leaders to understand the clinical microsystem of their unit such as their patient population, interdisciplinary care team, approach to process improvement, and performance patterns over time.[27]
General Shared Responsibilities of Physician and Nurse Unit Directors | Examples of Specific Activities |
---|---|
| |
Serve as management partners to enhance culture of the unit | Co‐craft and deliver consistent leadership message |
Co‐establish and enforce unit processes and protocols | |
Co‐lead recruitment and retention efforts | |
Co‐orient trainees and faculty rotating through unit | |
Co‐educate on the management of common medical and surgical conditions | |
Facilitate interstaff conflict resolution sessions | |
Regular leadership meetings | |
Actively manage unit processes and outcomes | Quality: improve core quality measure performance |
Safety: improve culture of patient safety within the unit as measured by surveys and incident reporting systems | |
Efficiency: reduce unnecessary length of stay and variability in resource use | |
Patient experience: focus on improving patient‐family experience with targeted outcomes in patient experience metrics (eg, HCAHPS) | |
Education: develop trainee and staff clinical and teamwork competencies | |
Continuous process improvement initiatives (eg, PDSA cycles) | Improve the discharge transitions process, tailoring the process to each individual patient's identified risk factors |
Focus improvement efforts on reduction in specific hospital acquired conditions such as CAUTI, VTE, CLABSI, pressure ulcers, falls | |
Measure, analyze, reassess, and improve in all described areas of shared responsibilities | |
Perform unit level chart reviews to evaluate readmissions and LOS and identify improvement opportunities |
In our collective experience, the dyad leaders bring passion and commitment to improving care; however, many (the medical directors in particular) have minimal prior formal training in leadership, quality improvement, or hospital management. Recognizing that unit leaders require specialized knowledge and skills, each of our organizations has enrolled unit medical directors and nurse managers in leadership development courses or educational programs. Many healthcare organizations have become more grounded in a QI methodology including Six‐Sigma, Lean Healthcare, PDSA, and other scientifically based methods, and the unit‐based leaders should receive advanced training in the preferred methods of their institution. Additional training in quality improvement, patient safety, and physician leadership can also be obtained through supplemental coursework specifically designed to train hospital leaders, with some programs leading to a certification or additional credentials.[28]
Beyond such formal educational opportunities, hospitals should not overlook the opportunity to learn from and share experiences with the other dyad leadership units within the hospital. One of the organizations described here holds monthly meetings with all of the unit dyad leaders, and 2 other organizations conduct quarterly meetings to share experiences and best practices related to specific improvement initiatives in a learning network model. Those units with more experience in specific initiatives are asked to share their lessons learned with others, as well as support each other in their efforts to collectively meet the strategic goals of the hospital.
Time and Organizational Support
In addition to leadership development, hospitals and the clinical department leadership need to support the medical directors with dedicated time away from their usual clinical duties. Some organizations in this report are providing up to 20% effort for the medical director's unit‐based leadership work; however, there is some variation in practice with regard to physician effort across sites. The University of Pennsylvania has a smaller effort support at 10%; however, some of that effort differential may be offset through the allocation of the quality improvement specialist/project manager assigned to work with the medical director and nurse manager dyad. St. Joseph Mercy Hospital also has a lower allocation, as there is additional financial compensation for the role that is at risk and not included in this 10% allocation.
It is also important to assure that the medical directors have institutional support to carry out their work in partnership with their nursing leadership. The 6 health systems described here report that although most of the physicians have appointments within a physician group or clinical department, there is hospital leadership oversight from a chief medical, nursing, or operating officer. This organizational structure may be an important aspect of the model as the unit‐based leaders seek to align their efforts with that of the hospital. Further, this form of organizational oversight can ensure that the unit leaders will receive timely and essential unit‐ and hospital‐based performance measures to manage local improvement efforts. These measures may include some components of patient experiences as reported in the Hospital Consumer Assessment of Healthcare Providers and Systems survey, readmission rates, hospital‐acquired condition rates, length of stay, observed to expected mortality rates, and results of staff satisfaction and safety culture surveys. As highlighted by several studies and commentaries, our collective experiences also identified interdisciplinary teamwork, collaboration, and communication as desirable outcome measures through the unit‐based leadership structure.[21, 22, 24, 29, 30] The medical director and nurse manager dyads can prioritize their improvement efforts based on the data provided to them, and mobilize the appropriate group of multidisciplinary practitioners and support staff on the unit.
OTHER CONSIDERATIONS
Other infrastructure variables that may increase the effectiveness of the unit leadership dyad include unit‐based clinical services (geographic localization), engaging the frontline team members in the design and implementation of change innovations, a commitment to patient and family centered practices on the unit, and enhancing clinical workflow through the support of EHR functions such as concurrent documentation and provider order entry. Geographic localization, placing the fewest possible clinical service providers on the unit to work alongside unit‐based staff, allows for a cohesive interdisciplinary unit‐based team to develop under the dyad leadership, and has been shown to improve communication practices.[9, 31] Beyond geographic localization of patients, it is critical to ensure team members are committed to the changes in workflow by directly involving them through the design and implementation of new models of care taking place on the unit. This commitment starts from the top senior nurse and physician leaders in the organization, and extends to the unit‐based dyad partners, and down to each individual interdisciplinary team member on the unit.[1] Thus, it is critical to clarify roles and responsibilities and how team members on the unit will interact with each other. For some situations, conflict management training will be helpful to the unit‐based leaders to resolve issues. To appreciate potential barriers to successful rollout of this unit leadership model, a phased implementation of pilot units, followed by successive waves, should be considered. Many of the units that instituted unit‐based interdisciplinary team rounds solicited and implemented direct feedback from frontline team members in efforts to improve communication and be more patient centered. Conversely, there are also likely to be situations where the unit‐based leaders will be confronted with hindrances to their unit‐based collaborative improvement efforts. To help prepare the dyad leaders, many of our unit‐based leaders have received specific training on how to coach and conduct difficult conversations with individuals who have performance gaps or are perceived to be hindering the progress of the unit's work. These crucial negotiation skills are not innate among most managers and should be explicitly provided to new leaders across organizations.
The goals and merits of patient‐ and family‐centered care (PFCC) have been well described.[32, 33, 34] Organizational support to teach and disseminate PFCC practices throughout all settings of care may help the leadership dyads implement rounding strategies that engage all staff, patients, and family members throughout the hospital course and during the transitions out of the hospital.
Clinical workflow has become heavily dependent on the EHR systems. For those organizations that have yet to adopt a particular EHR system, the leadership dyads should be involved throughout the EHR design process to help ensure that the technological solutions will be built to assist the clinical workflow, and once the system has been built, the leadership dyad should monitor and enhance the interface between workflow and EHR system so that it can support the creation and advancement of interdisciplinary plans of care on the unit.
CONCLUSION
The care of the hospitalized patient has become more complex over time. Interdisciplinary teamwork needs to be improved at the unit level to achieve the strategic goals of the hospital. Although quality improvement is an organizational goal, change takes place locally. Physician leaders, in partnership with nurse managers, are needed now more than ever to take on this task to improve the hospital‐care experience for patients by functioning as the primary effector arms for changing the landscape of hospital‐based care. We have described characteristics of unit‐based leadership programs adopted across 6 organizations. Hospitalists with clinical experience as the principal providers of inpatient‐based care and quality improvement experience and training, have been key participants in the development and implementation of the local leadership models in each of these hospital systems. We hope the comparison of the various models featured in this article serves as a valuable reference to hospitals and healthcare organizations who are contemplating the incorporation of this model into their strategic plan.
Hospital‐based care has become more complex over time. Patients are sicker, with more chronic comorbid conditions requiring greater collaboration to provide coordinated patient care.[1, 2] Care coordination requires an interdisciplinary approach during hospitalization and especially during transitions of care.[3, 4] In addition, hospitals are tasked with managing and improving clinical workflow efficiencies, and implementing electronic health records (EHR)[5] that require healthcare professionals to learn new systems of care and technology. Payment models have also started to shift toward an incentive and penalty‐based structure in the form of value‐based purchasing, readmission penalties, hospital‐acquired conditions, and meaningful use.[4, 6]
In response to these pressures, hospitals are searching for ways to reliably deliver quality care that is safe, effective, patient centered, timely, efficient, and equitable.[7] Previous efforts to improve quality in the general medical inpatient setting have included redesign of the clinical work environment and new workflows through the use of checklists and whiteboards to enhance communication, patient‐centered bedside rounds, standardized protocols and handovers, and integrated clinical decision support using health information technology.[8, 9, 10, 11, 12, 13] Although each of these care coordination activities has potential value, integrating them at the unit level often remains a challenge. Some hospitals have addressed this challenge by establishing and supporting a unit‐based leadership model, where a medical director and nurse manager work together to assess and improve the quality, safety, efficiency, and patient experience‐based mission of the organization.[14, 15] However, there are few descriptions of this leadership model in the current literature. Herein, we present the unit‐based leadership model that has been developed and implemented at 6 hospitals.
MODELS OF UNIT‐BASED LEADERSHIP
The unit‐based leadership model is grounded on the idea that culture and clinical care are products of frontline structure, process, and relationships, and that leaders at the site of care can have the greatest influence on the local work environment.[16, 17] The objective is to influence care and culture at the bedside and the unit, where care is delivered and where alignment with organizational vision and mission must occur. The concept of the inpatient unit medical director is not new, and hospitals in the past have recruited physician leaders to become clinical champions for quality improvement and help establish a collaborative work environment for physicians and unit‐based staff.[18, 19, 20, 21, 22] These studies report on the challenges and benefits of incorporating a medical director to inpatient psychiatry or general care units, but do not provide specific details about the recruitment and responsibilities for unit‐based dyad partnerships, which are critical factors for success on multidisciplinary inpatient care units.
There are several logistical matters to consider when instituting a unit‐based leadership model. These include the composition of the leadership team, selection process of the leaders, the presence of trainees and permanent faculty, and whether the units are able to geographically cohort patients. Other considerations include a clear role description with established shared goals and expectations, and a compensation model that includes effort and incentives. In addition, there should be a clearly established reporting structure to senior leadership, and the unit leaders should be given opportunities for professional growth and development. Table 1 provides a summary overview of 6 hospitals' experiences to date.
Structure | Hospital of the University of Pennsylvania | Northwestern Memorial Hospital | Emory University Hospital | University of Michigan Health System | Christiana Care Health System | St. Joseph Mercy Health System/Integrated Health Associates |
---|---|---|---|---|---|---|
| ||||||
Description of hospital(s) | Academic medical center, 784 beds, 40,000 annual admissions | Academic medical center, 897 beds, 53,000 annual admissions | Academic medical center, 579 beds, 24,000 annual admissions | Academic medical center, 839 beds, 45,000 annual admissions | Independent academic medical center, 1,100 beds, 53,000 annual admissions | Tertiary community hospital that is part of a larger health care system (Trinity Health), 579 beds, 33,000 annual admissions |
Unit leadership model | Triad of medical director, nurse manager, and quality improvement specialist/project manager | Dyad of medical director and nurse manager | Dyad of medical director and nurse manager | Dyad of medical director and nurse manager | Dyad of medical director and nurse manager | Dyad of medical director and nurse manager |
Percent effort time supported for unit medical director | 10% | 17% | 10% | 20% | 20% | 10% |
Incentives built into unit leaders' performance in outcomes metrics | No | Yes | No | No | No | Yes |
Professional development/leadership training | Quality improvement method: PDSA, Six Sigma, Lean Healthcare | Quality improvement method: Six Sigma | Situational leadership training with 1:1 mentoring | Quality improvement method: Lean Healthcare, service excellence program | Quality Improvement method: Six Sigma, Lean Healthcare | Quality improvement method: Six Sigma |
Additional leadership development through Penn Medicine Leadership Academy and Wharton Executive Education | Additional leadership development through Northwestern's professional development center and simulation training center | Conflict resolution skill development | Attend patient and Family Centered Care conference | Additional leadership development through Christiana Care Learning Institute | Attend educational course on Crucial Conversations | |
Personality profile with coaching | Additional leadership development through University of Michigan Health System's human resources group | |||||
Outcomes metrics monitored | Patient satisfaction | Patient satisfaction | Patient satisfaction | Patient satisfaction | Patient satisfaction | Patient satisfaction |
Efficiency of multidisciplinary rounds | Teamwork climate (survey) | Teamwork and implementation of structured interdisciplinary bedside rounds | Multidisciplinary rounds | Interdisciplinary rounds | Participation in interdisciplinary rounds | |
RNMD work environment surveys | Adverse events | Unit‐based patient safety culture survey | Patient‐centered, bedside rounds | Readmission rates | ||
Hospital‐acquired conditions (CAUTI, CLABSI, VAP, DVT, pressure ulcers) | Hospital‐acquired conditions (fall rates, pressure ulcers | Hospital‐acquired conditions (CAUTI, CLABSI, fall rates, pressure ulcers) | Hospital‐acquired conditions (CAUTI) | Hospital‐acquired conditions (fall rates, pressure ulcers) | Core measures | |
Readmission rates | Readmission rates | Mortality | Readmission rates | Readmission rates | Medication reconciliation | |
Core measures, patient safety indicators | Core measures | Length of stay | DVT prophylaxis | Hand hygiene | Discharge by 11 am | |
Mortality (observed to expected, transfer, inpatient) | Hand hygiene | Glycemic control | Meeting attendance | Length of stay | Use of patient teach‐back | |
Medication reconciliation | Restraint use | Communication with PCPs | ||||
Home care, hospice, post‐acute care referral rates | ||||||
Organizational leadership structure support for clinical unit partnership program | CMO, CNO, vice president of quality/patient safety, directors of medical and surgical nursing | Associate chair of medicine, director of medicine nursing; all medical directors are members of the department of medicine quality management committee | CMO, CNO, CEO, CQO | CMO, CNO | All teams report to and are supported by 3 overarching, system‐wide committees: (1) safety first, (2) think of yourself as a patient, (3) clinical excellence. Those committees, in turn, report up to the senior management quality/safety coordinating council. | Director of hospitalist program (reports to CMO); nursing director of acute care (reports to CNO) |
DISCUSSION
In reviewing our 6 organization's collective experiences, we identified several common themes and some notable differences across sites. The core of the leadership team was primarily composed of the medical director and nurse manager on the unit. Across all 6 organizations, medical directors had a portion of their effort supported for their leadership work on the unit. Leadership development training was provided at all of our sites, with particular emphasis on quality improvement (QI) methods such as Six‐Sigma, Lean, or Plan, Do, Study, Act (PDSA). Additional leadership development sessions were provided through the organization's human resources or affiliated university. Common outcome measures of interest include patient satisfaction, interdisciplinary practice, and collaboration on the unit, and some hospital‐acquired condition measures. Last, there is a direct reporting relationship to a chief or senior nurse or physician leader within each organization. These commonalities and variances are further detailed below.
Establishing the Unit‐Based Leadership Model
The composition of the unit‐based leadership model in our 6 organizations is predominantly a dyad partnership of medical directors and nurse managers. Although informal physician‐nurse collaborative practices have likely been in existence at many hospitals, formalizing this dyad partnership is an important step to fostering collaborative efforts to improve quality of care. It is also essential for hospital leadership to clearly articulate the need for this unit‐based leadership model. Whether the motivation for change is from a previously untenable practice environment, or part of an ongoing improvement program, the model should be presented in a manner that supports the organization's commitment to improve collaborative practices for better patient care. One of our 6 hospitals initiated this leadership model based on troubling relationships between nurses and physicians on some of their inpatient care units, which threatened to stall the organization's Magnet application. Implementation of the leadership model at the unit level yielded improvements in nursephysician interactions, patient satisfaction, and staff turnover.[15, 23] Another of the hospitals first evaluated why a previous attempt at this model did not deliver the intended outcomes, and redesigned the model based on its analysis.[14]
Across all of the organizations featured here, a common driver behind the adoption of the unit‐based leadership model was to bridge the divide between physician services and nursing and other allied health providers. We found that many of the physicians routinely had patients on multiple units, limiting the quantity and quality of collaborative practices between unit‐based staff and physician teams. The unit‐based dyad leaders are ideally positioned to build and foster a culture of collaboration, and our organizations have been inclusive to ensure the participation of a multidisciplinary group of providers, including representatives from pharmacy, environmental services, physical therapy, respiratory therapy, social work, case management, and nutrition at leadership meetings or in daily patient‐care discussions. In addition, 2 of the organizations have added quality improvement specialist/project managers to their teams to support the physiciannurse manager leaders on the unit.
Selection Process and Professional Development
The traditional approach to hiring a physician leader or a nurse manager has been an isolated process of drafting a job description for each position and hiring within their respective departments. For the dyad partnership to be successful, there should be established goals and expectations that require shared responsibilities between the 2 partners, which should guide the selection of these leaders. Other leadership attributes and essential character traits that should be modeled by the unit‐based leaders include good communication skills, respect among coworkers, and a collaborative approach to decision making and action. In addition, both physician leaders and nurse managers in these roles should have the ability to take a system's view, recognizing that within the complex network of healthcare providers and processes on their unit, these elements interact with each other, which lead to the outcomes achieved on their units.[24, 25] Table 2 lists some general shared responsibilities, highlighting specific activities that can be used to achieve the established outcomes. As the unit's dyad leadership works together to address these shared responsibilities, they should keep their sights focused on the overall strategic goals of the healthcare organization. Bohmer has defined 4 habits of the high‐value healthcare organization that in turn can be reflected through the inpatient unit leadership model to capture these activities at the local level: (1) planning care for specific patient populations, (2) microsystem design, (3) measurement and oversight, and (4) self‐study.[26] In determining specific shared responsibilities for each dyad partner, it is important for these leaders to understand the clinical microsystem of their unit such as their patient population, interdisciplinary care team, approach to process improvement, and performance patterns over time.[27]
General Shared Responsibilities of Physician and Nurse Unit Directors | Examples of Specific Activities |
---|---|
| |
Serve as management partners to enhance culture of the unit | Co‐craft and deliver consistent leadership message |
Co‐establish and enforce unit processes and protocols | |
Co‐lead recruitment and retention efforts | |
Co‐orient trainees and faculty rotating through unit | |
Co‐educate on the management of common medical and surgical conditions | |
Facilitate interstaff conflict resolution sessions | |
Regular leadership meetings | |
Actively manage unit processes and outcomes | Quality: improve core quality measure performance |
Safety: improve culture of patient safety within the unit as measured by surveys and incident reporting systems | |
Efficiency: reduce unnecessary length of stay and variability in resource use | |
Patient experience: focus on improving patient‐family experience with targeted outcomes in patient experience metrics (eg, HCAHPS) | |
Education: develop trainee and staff clinical and teamwork competencies | |
Continuous process improvement initiatives (eg, PDSA cycles) | Improve the discharge transitions process, tailoring the process to each individual patient's identified risk factors |
Focus improvement efforts on reduction in specific hospital acquired conditions such as CAUTI, VTE, CLABSI, pressure ulcers, falls | |
Measure, analyze, reassess, and improve in all described areas of shared responsibilities | |
Perform unit level chart reviews to evaluate readmissions and LOS and identify improvement opportunities |
In our collective experience, the dyad leaders bring passion and commitment to improving care; however, many (the medical directors in particular) have minimal prior formal training in leadership, quality improvement, or hospital management. Recognizing that unit leaders require specialized knowledge and skills, each of our organizations has enrolled unit medical directors and nurse managers in leadership development courses or educational programs. Many healthcare organizations have become more grounded in a QI methodology including Six‐Sigma, Lean Healthcare, PDSA, and other scientifically based methods, and the unit‐based leaders should receive advanced training in the preferred methods of their institution. Additional training in quality improvement, patient safety, and physician leadership can also be obtained through supplemental coursework specifically designed to train hospital leaders, with some programs leading to a certification or additional credentials.[28]
Beyond such formal educational opportunities, hospitals should not overlook the opportunity to learn from and share experiences with the other dyad leadership units within the hospital. One of the organizations described here holds monthly meetings with all of the unit dyad leaders, and 2 other organizations conduct quarterly meetings to share experiences and best practices related to specific improvement initiatives in a learning network model. Those units with more experience in specific initiatives are asked to share their lessons learned with others, as well as support each other in their efforts to collectively meet the strategic goals of the hospital.
Time and Organizational Support
In addition to leadership development, hospitals and the clinical department leadership need to support the medical directors with dedicated time away from their usual clinical duties. Some organizations in this report are providing up to 20% effort for the medical director's unit‐based leadership work; however, there is some variation in practice with regard to physician effort across sites. The University of Pennsylvania has a smaller effort support at 10%; however, some of that effort differential may be offset through the allocation of the quality improvement specialist/project manager assigned to work with the medical director and nurse manager dyad. St. Joseph Mercy Hospital also has a lower allocation, as there is additional financial compensation for the role that is at risk and not included in this 10% allocation.
It is also important to assure that the medical directors have institutional support to carry out their work in partnership with their nursing leadership. The 6 health systems described here report that although most of the physicians have appointments within a physician group or clinical department, there is hospital leadership oversight from a chief medical, nursing, or operating officer. This organizational structure may be an important aspect of the model as the unit‐based leaders seek to align their efforts with that of the hospital. Further, this form of organizational oversight can ensure that the unit leaders will receive timely and essential unit‐ and hospital‐based performance measures to manage local improvement efforts. These measures may include some components of patient experiences as reported in the Hospital Consumer Assessment of Healthcare Providers and Systems survey, readmission rates, hospital‐acquired condition rates, length of stay, observed to expected mortality rates, and results of staff satisfaction and safety culture surveys. As highlighted by several studies and commentaries, our collective experiences also identified interdisciplinary teamwork, collaboration, and communication as desirable outcome measures through the unit‐based leadership structure.[21, 22, 24, 29, 30] The medical director and nurse manager dyads can prioritize their improvement efforts based on the data provided to them, and mobilize the appropriate group of multidisciplinary practitioners and support staff on the unit.
OTHER CONSIDERATIONS
Other infrastructure variables that may increase the effectiveness of the unit leadership dyad include unit‐based clinical services (geographic localization), engaging the frontline team members in the design and implementation of change innovations, a commitment to patient and family centered practices on the unit, and enhancing clinical workflow through the support of EHR functions such as concurrent documentation and provider order entry. Geographic localization, placing the fewest possible clinical service providers on the unit to work alongside unit‐based staff, allows for a cohesive interdisciplinary unit‐based team to develop under the dyad leadership, and has been shown to improve communication practices.[9, 31] Beyond geographic localization of patients, it is critical to ensure team members are committed to the changes in workflow by directly involving them through the design and implementation of new models of care taking place on the unit. This commitment starts from the top senior nurse and physician leaders in the organization, and extends to the unit‐based dyad partners, and down to each individual interdisciplinary team member on the unit.[1] Thus, it is critical to clarify roles and responsibilities and how team members on the unit will interact with each other. For some situations, conflict management training will be helpful to the unit‐based leaders to resolve issues. To appreciate potential barriers to successful rollout of this unit leadership model, a phased implementation of pilot units, followed by successive waves, should be considered. Many of the units that instituted unit‐based interdisciplinary team rounds solicited and implemented direct feedback from frontline team members in efforts to improve communication and be more patient centered. Conversely, there are also likely to be situations where the unit‐based leaders will be confronted with hindrances to their unit‐based collaborative improvement efforts. To help prepare the dyad leaders, many of our unit‐based leaders have received specific training on how to coach and conduct difficult conversations with individuals who have performance gaps or are perceived to be hindering the progress of the unit's work. These crucial negotiation skills are not innate among most managers and should be explicitly provided to new leaders across organizations.
The goals and merits of patient‐ and family‐centered care (PFCC) have been well described.[32, 33, 34] Organizational support to teach and disseminate PFCC practices throughout all settings of care may help the leadership dyads implement rounding strategies that engage all staff, patients, and family members throughout the hospital course and during the transitions out of the hospital.
Clinical workflow has become heavily dependent on the EHR systems. For those organizations that have yet to adopt a particular EHR system, the leadership dyads should be involved throughout the EHR design process to help ensure that the technological solutions will be built to assist the clinical workflow, and once the system has been built, the leadership dyad should monitor and enhance the interface between workflow and EHR system so that it can support the creation and advancement of interdisciplinary plans of care on the unit.
CONCLUSION
The care of the hospitalized patient has become more complex over time. Interdisciplinary teamwork needs to be improved at the unit level to achieve the strategic goals of the hospital. Although quality improvement is an organizational goal, change takes place locally. Physician leaders, in partnership with nurse managers, are needed now more than ever to take on this task to improve the hospital‐care experience for patients by functioning as the primary effector arms for changing the landscape of hospital‐based care. We have described characteristics of unit‐based leadership programs adopted across 6 organizations. Hospitalists with clinical experience as the principal providers of inpatient‐based care and quality improvement experience and training, have been key participants in the development and implementation of the local leadership models in each of these hospital systems. We hope the comparison of the various models featured in this article serves as a valuable reference to hospitals and healthcare organizations who are contemplating the incorporation of this model into their strategic plan.
- Organizational predictors of coordination in inpatient medicine [published online ahead of print February 26, 2014]. Health Care Manage Rev. doi: 10.1097/HMR.0000000000000004. , , , et al.
- Trends in case‐mix in the medicare population. Paper presented at: American Hospital Association, Federation of American Hospitals, Association of American Medical Colleges; http://www.aha.org/content/00‐10/100715‐CMItrends.pdf. July 15, 2010. .
- A requirement to reduce readmissions: take care of the patient, not just the disease. JAMA. 2013;309(4):394–396. .
- Value‐based purchasing—national programs to move from volume to value. N Engl J Med. 2012;367(4):292–295. , .
- Medicare and Medicaid programs; electronic health record incentive program. Final rule. Fed Regist. 2010;75(144):44313–44588.
- The Center for Medicare and Medicaid innovation's blueprint for rapid‐cycle evaluation of new care and payment models. Health Aff (Millwood). 2013;32(4):807–812. .
- Institute of Medicine. Crossing the Quality Chasm: A New Health System for the 21st Century. Washington, DC: National Academies Press; 2001.
- Improving teamwork: impact of structured interdisciplinary rounds on a medical teaching unit. J Gen Intern Med. 2010;25(8):826–832. , , , , , .
- Impact of localizing physicians to hospital units on nurse‐physician communication and agreement on the plan of care. J Gen Intern Med. 2009;24(11):1223–1227. , , , et al.
- A review on systematic reviews of health information system studies. J Am Med Inform Assoc. 2010;17(6):637–645. , , , .
- Patient whiteboards as a communication tool in the hospital setting: a survey of practices and recommendations. J Hosp Med. Apr 2010;5(4):234–239. , , , , .
- Development of a checklist for documenting team and collaborative behaviors during multidisciplinary bedside rounds. J Nurs Adm. 2013;43(5):280–285. , , .
- Assessment of teamwork during structured interdisciplinary rounds on medical units. J Hosp Med. 2012;7(9):679–683. , , , , .
- Leadership at the front line: a clinical partnership model on general care inpatient units. Am J Med Qual. 2012;27(2):106–111. , , , et al.
- AHRQ health care innovations exchange: improvement projects led by unit‐based teams of nurse, physician, and quality leaders reduce infections, lower costs, improve patient satisfaction, and nurse‐physician communication. Available at: http://www.innovations.ahrq.gov/content.aspx?id=2719. Published April 14, 2010. Accessed November 26, 2011. , .
- Microsystems in health care: part 8. Developing people and improving work life: what front‐line staff told us. Jt Comm J Qual Saf. 2003;29(10):512–522. , , , , , .
- Microsystems in health care: part 5. How leaders are leading. Jt Comm J Qual Saf. 2003;29(6):297–308. , , , et al.
- The academic dilemma of the inpatient unit director. Am J Psychiatry. 1989;146(1):73–76. , , .
- Improving and sustaining core measure performance through effective accountability of clinical microsystems in an academic medical center. Jt Comm J Qual Patient Saf. 2010;36(9):387–398. , , , , .
- Physician leadership and quality improvement in the acute child and adolescent psychiatric care setting. Child Adolesc Psychiatr Clin N Am. 2010;19(1):1–19; table of contents. , , .
- Effect of a multidisciplinary intervention on communication and collaboration among physicians and nurses. Am J Crit Care. 2005;14(1):71–77. , , , .
- Nurse‐physician leadership: insights into interprofessional collaboration. J Nurs Adm. 2013;43(12):653–659. , .
- The Advisory Board. University of Pennsylvania Health System pilots unit clinical leadership model to spur quality gains. Nurs Exec Watch. 2008;9(2):4–6.
- Physicians as leaders in improving health care: a new series in Annals of Internal Medicine. Ann Intern Med. 1998;128(4):289–292. , .
- Understanding medical systems. Ann Intern Med. 1998;128(4):293–298. .
- The four habits of high‐value health care organizations. N Engl J Med. 2011;365(22):2045–2047. .
- Microsystems in health care: Part 1. Learning from high‐performing front‐line clinical units. Jt Comm J Qual Improv. 2002;28(9):472–493. , , , et al.
- The quality and safety educators academy: fulfilling an unmet need for faculty development. Am J Med Qual. 2014;29(1):5–12. , , , et al.
- Cooperation: the foundation of improvement. Ann Intern Med. 1998;128(12 pt 1):1004–1009. , , , .
- Ten principles of good interdisciplinary team work. Hum Resour Health 2013;11(1):19. , , , , , .
- Impact of localizing general medical teams to a single nursing unit. J Hosp Med. 2012;7(7):551–556. , , , et al.
- Integrating patient‐ and family‐centered care with health policy: four proposed policy approaches. Qual Manag Health Care. 2013;22(2):137–145. , , , .
- Incorporating patient‐ and family‐centered care into resident education: approaches, benefits, and challenges. J Grad Med Educ. 2011;3(2):272–278. , , .
- Smith M, Saunders R, Stuckhardt L, McGinnis JM, eds. Best Care at Lower Cost: The Path to Continuously Learning Health Care in America. Washington, DC: National Academies Press; 2012.
- Organizational predictors of coordination in inpatient medicine [published online ahead of print February 26, 2014]. Health Care Manage Rev. doi: 10.1097/HMR.0000000000000004. , , , et al.
- Trends in case‐mix in the medicare population. Paper presented at: American Hospital Association, Federation of American Hospitals, Association of American Medical Colleges; http://www.aha.org/content/00‐10/100715‐CMItrends.pdf. July 15, 2010. .
- A requirement to reduce readmissions: take care of the patient, not just the disease. JAMA. 2013;309(4):394–396. .
- Value‐based purchasing—national programs to move from volume to value. N Engl J Med. 2012;367(4):292–295. , .
- Medicare and Medicaid programs; electronic health record incentive program. Final rule. Fed Regist. 2010;75(144):44313–44588.
- The Center for Medicare and Medicaid innovation's blueprint for rapid‐cycle evaluation of new care and payment models. Health Aff (Millwood). 2013;32(4):807–812. .
- Institute of Medicine. Crossing the Quality Chasm: A New Health System for the 21st Century. Washington, DC: National Academies Press; 2001.
- Improving teamwork: impact of structured interdisciplinary rounds on a medical teaching unit. J Gen Intern Med. 2010;25(8):826–832. , , , , , .
- Impact of localizing physicians to hospital units on nurse‐physician communication and agreement on the plan of care. J Gen Intern Med. 2009;24(11):1223–1227. , , , et al.
- A review on systematic reviews of health information system studies. J Am Med Inform Assoc. 2010;17(6):637–645. , , , .
- Patient whiteboards as a communication tool in the hospital setting: a survey of practices and recommendations. J Hosp Med. Apr 2010;5(4):234–239. , , , , .
- Development of a checklist for documenting team and collaborative behaviors during multidisciplinary bedside rounds. J Nurs Adm. 2013;43(5):280–285. , , .
- Assessment of teamwork during structured interdisciplinary rounds on medical units. J Hosp Med. 2012;7(9):679–683. , , , , .
- Leadership at the front line: a clinical partnership model on general care inpatient units. Am J Med Qual. 2012;27(2):106–111. , , , et al.
- AHRQ health care innovations exchange: improvement projects led by unit‐based teams of nurse, physician, and quality leaders reduce infections, lower costs, improve patient satisfaction, and nurse‐physician communication. Available at: http://www.innovations.ahrq.gov/content.aspx?id=2719. Published April 14, 2010. Accessed November 26, 2011. , .
- Microsystems in health care: part 8. Developing people and improving work life: what front‐line staff told us. Jt Comm J Qual Saf. 2003;29(10):512–522. , , , , , .
- Microsystems in health care: part 5. How leaders are leading. Jt Comm J Qual Saf. 2003;29(6):297–308. , , , et al.
- The academic dilemma of the inpatient unit director. Am J Psychiatry. 1989;146(1):73–76. , , .
- Improving and sustaining core measure performance through effective accountability of clinical microsystems in an academic medical center. Jt Comm J Qual Patient Saf. 2010;36(9):387–398. , , , , .
- Physician leadership and quality improvement in the acute child and adolescent psychiatric care setting. Child Adolesc Psychiatr Clin N Am. 2010;19(1):1–19; table of contents. , , .
- Effect of a multidisciplinary intervention on communication and collaboration among physicians and nurses. Am J Crit Care. 2005;14(1):71–77. , , , .
- Nurse‐physician leadership: insights into interprofessional collaboration. J Nurs Adm. 2013;43(12):653–659. , .
- The Advisory Board. University of Pennsylvania Health System pilots unit clinical leadership model to spur quality gains. Nurs Exec Watch. 2008;9(2):4–6.
- Physicians as leaders in improving health care: a new series in Annals of Internal Medicine. Ann Intern Med. 1998;128(4):289–292. , .
- Understanding medical systems. Ann Intern Med. 1998;128(4):293–298. .
- The four habits of high‐value health care organizations. N Engl J Med. 2011;365(22):2045–2047. .
- Microsystems in health care: Part 1. Learning from high‐performing front‐line clinical units. Jt Comm J Qual Improv. 2002;28(9):472–493. , , , et al.
- The quality and safety educators academy: fulfilling an unmet need for faculty development. Am J Med Qual. 2014;29(1):5–12. , , , et al.
- Cooperation: the foundation of improvement. Ann Intern Med. 1998;128(12 pt 1):1004–1009. , , , .
- Ten principles of good interdisciplinary team work. Hum Resour Health 2013;11(1):19. , , , , , .
- Impact of localizing general medical teams to a single nursing unit. J Hosp Med. 2012;7(7):551–556. , , , et al.
- Integrating patient‐ and family‐centered care with health policy: four proposed policy approaches. Qual Manag Health Care. 2013;22(2):137–145. , , , .
- Incorporating patient‐ and family‐centered care into resident education: approaches, benefits, and challenges. J Grad Med Educ. 2011;3(2):272–278. , , .
- Smith M, Saunders R, Stuckhardt L, McGinnis JM, eds. Best Care at Lower Cost: The Path to Continuously Learning Health Care in America. Washington, DC: National Academies Press; 2012.