This month in CHEST : Editor’s picks

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Editorial

Spread the Word About CHEST for 2017: Collaboration With Elsevier, Publishing of Guidelines, More Multimedia Content, and Changes for Reviewers and Authors. By Dr. Richard S. Irwin; Dr. John E. Heffner; Jean Rice; Dr. Cynthia T. French; on behalf of the Editorial Leadership Team.

Point Counterpoint Editorial

POINT: Will New Anti-eosinophilic Drugs Be Useful In Asthma Management?

Yes. Dr. P.M. O’Byrne

No. Dr. P. Barnes

Giants in Chest Medicine

Dr. Claude Lenfant. By Dr. E.J. Roccella.

Special Feature

The Eighth Edition Lung Cancer Stage Classification. By Dr. F.C. Detterbeck, et al.

Evidence-based MedicineLiberation From Mechanical Ventilation in Critically Ill Adults: Executive Summary of an Official American College of Chest Physicians/American Thoracic Society Clinical Practice Guideline. By Dr. G.A. Schmidt, et al.

Original ResearchEffect of Procalcitonin Testing on Health-care Utilization and Costs in Critically Ill Patients in the United States. By Dr. R.A. Balk, et al.

Use of Palliative Care in Patients With End-Stage COPD and Receiving Home Oxygen: National Trends and Barriers to Care in the United States. By Dr. B. Rush, et al.

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Editorial

Spread the Word About CHEST for 2017: Collaboration With Elsevier, Publishing of Guidelines, More Multimedia Content, and Changes for Reviewers and Authors. By Dr. Richard S. Irwin; Dr. John E. Heffner; Jean Rice; Dr. Cynthia T. French; on behalf of the Editorial Leadership Team.

Point Counterpoint Editorial

POINT: Will New Anti-eosinophilic Drugs Be Useful In Asthma Management?

Yes. Dr. P.M. O’Byrne

No. Dr. P. Barnes

Giants in Chest Medicine

Dr. Claude Lenfant. By Dr. E.J. Roccella.

Special Feature

The Eighth Edition Lung Cancer Stage Classification. By Dr. F.C. Detterbeck, et al.

Evidence-based MedicineLiberation From Mechanical Ventilation in Critically Ill Adults: Executive Summary of an Official American College of Chest Physicians/American Thoracic Society Clinical Practice Guideline. By Dr. G.A. Schmidt, et al.

Original ResearchEffect of Procalcitonin Testing on Health-care Utilization and Costs in Critically Ill Patients in the United States. By Dr. R.A. Balk, et al.

Use of Palliative Care in Patients With End-Stage COPD and Receiving Home Oxygen: National Trends and Barriers to Care in the United States. By Dr. B. Rush, et al.

 

Editorial

Spread the Word About CHEST for 2017: Collaboration With Elsevier, Publishing of Guidelines, More Multimedia Content, and Changes for Reviewers and Authors. By Dr. Richard S. Irwin; Dr. John E. Heffner; Jean Rice; Dr. Cynthia T. French; on behalf of the Editorial Leadership Team.

Point Counterpoint Editorial

POINT: Will New Anti-eosinophilic Drugs Be Useful In Asthma Management?

Yes. Dr. P.M. O’Byrne

No. Dr. P. Barnes

Giants in Chest Medicine

Dr. Claude Lenfant. By Dr. E.J. Roccella.

Special Feature

The Eighth Edition Lung Cancer Stage Classification. By Dr. F.C. Detterbeck, et al.

Evidence-based MedicineLiberation From Mechanical Ventilation in Critically Ill Adults: Executive Summary of an Official American College of Chest Physicians/American Thoracic Society Clinical Practice Guideline. By Dr. G.A. Schmidt, et al.

Original ResearchEffect of Procalcitonin Testing on Health-care Utilization and Costs in Critically Ill Patients in the United States. By Dr. R.A. Balk, et al.

Use of Palliative Care in Patients With End-Stage COPD and Receiving Home Oxygen: National Trends and Barriers to Care in the United States. By Dr. B. Rush, et al.

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Introducing our new Editorial Board Members

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Dr. M. Patricia Rivera
M. Patricia Rivera, MD, FCCP, is a Professor of Medicine in the Pulmonary Division, Department of Medicine at the University of North Carolina at Chapel Hill. She is a Co-Director of the Multidisciplinary Thoracic Oncology Program, and Director of the Lung Cancer Screening Program at UNC. She currently serves as Co-chair of the CHEST Thoracic Oncology NetWork and has been an editor and writer for the CHEST Lung Cancer Guidelines.

Dr. Nirmal S. Sharma
Nirmal S. Sharma, MD, is an Assistant Professor of Medicine in the Division of Pulmonary, Allergy and Critical Care Medicine at the University of Alabama at Birmingham. His clinical expertise is in the field of lung transplantation and advanced lung diseases including extracorporeal life support technologies for acute respiratory failure. His research is focused on the interaction of lung microbiome and innate immunity and its role in causing chronic rejection in lung transplantation. His other clinical interests include management of acute respiratory distress syndrome, pulmonary embolism, and lung donor management.
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Dr. M. Patricia Rivera
M. Patricia Rivera, MD, FCCP, is a Professor of Medicine in the Pulmonary Division, Department of Medicine at the University of North Carolina at Chapel Hill. She is a Co-Director of the Multidisciplinary Thoracic Oncology Program, and Director of the Lung Cancer Screening Program at UNC. She currently serves as Co-chair of the CHEST Thoracic Oncology NetWork and has been an editor and writer for the CHEST Lung Cancer Guidelines.

Dr. Nirmal S. Sharma
Nirmal S. Sharma, MD, is an Assistant Professor of Medicine in the Division of Pulmonary, Allergy and Critical Care Medicine at the University of Alabama at Birmingham. His clinical expertise is in the field of lung transplantation and advanced lung diseases including extracorporeal life support technologies for acute respiratory failure. His research is focused on the interaction of lung microbiome and innate immunity and its role in causing chronic rejection in lung transplantation. His other clinical interests include management of acute respiratory distress syndrome, pulmonary embolism, and lung donor management.

 

Dr. M. Patricia Rivera
M. Patricia Rivera, MD, FCCP, is a Professor of Medicine in the Pulmonary Division, Department of Medicine at the University of North Carolina at Chapel Hill. She is a Co-Director of the Multidisciplinary Thoracic Oncology Program, and Director of the Lung Cancer Screening Program at UNC. She currently serves as Co-chair of the CHEST Thoracic Oncology NetWork and has been an editor and writer for the CHEST Lung Cancer Guidelines.

Dr. Nirmal S. Sharma
Nirmal S. Sharma, MD, is an Assistant Professor of Medicine in the Division of Pulmonary, Allergy and Critical Care Medicine at the University of Alabama at Birmingham. His clinical expertise is in the field of lung transplantation and advanced lung diseases including extracorporeal life support technologies for acute respiratory failure. His research is focused on the interaction of lung microbiome and innate immunity and its role in causing chronic rejection in lung transplantation. His other clinical interests include management of acute respiratory distress syndrome, pulmonary embolism, and lung donor management.
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Kidney Disease Progression: How to Calculate Risk

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Kidney Disease Progression: How to Calculate Risk

Q)When I diagnose patients with minor kidney disease, they often ask if they will require dialysis. I know it is unlikely, but I wish I could give them a better answer. Can you help me?

 

The diagnosis of chronic kidney disease (CKD) is understandably concerning for many patients. Being able to estimate CKD progression helps patients gain a better understanding of their condition while allowing clinicians to develop more personalized care plans. Tangri and colleagues developed a model that can be used to predict risk for kidney failure requiring dialysis or transplantation in patients with stage III to V CKD. This model has been validated in multiple diverse populations in North America and worldwide.1

The Kidney Failure Risk Equation (found at www.kidneyfailurerisk.com) uses four variables—age, gender, glomerular filtration rate (GFR), and urine albumin-to-creatinine ratio (ACR)—to assess two- and five-year risk for kidney failure.1,2 For example

  • A 63-year-old woman with a GFR of 45 mL/min and an ACR of 30 mg/g has a 0.4% two-year risk and a 1.3% five-year risk for progression to kidney failure requiring dialysis or transplant.1
  • Alternatively, a 55-year-old man with a GFR of 38 mL/min and an ACR of 150 mg/g has a 2.9% two-year risk and a 9% five-year risk for progression to end-stage renal disease (ESRD).1
 

 

 

Per proposed thresholds, patients with a score < 5% would be deemed “low risk”; with scores of 5% to 15%, “intermediate risk”; and with scores > 15%, “high risk.”1,2

The Kidney Failure Risk Equation can be incorporated into clinic visits to provide context for lab results. For patients with low risk for progression, optimal care and lifestyle measures can be reinforced. For those with intermediate or high risk, more intensive treatments and appropriate referrals can be initiated. (The National Kidney Foundation advises referral when a patient’s estimated GFR is 20 mL/min or the urine ACR is ≥ 300 mg/g.3) Providing a numeric risk for progression can help alleviate the patient’s uncertainty surrounding the diagnosis of CKD. —NDM

Nicole D. McCormick, MS, MBA, NP-C, CCTC
University of Colorado Renal Transplant Clinic, Aurora, Colorado

References

1. Tangri N, Grams ME, Levey AS, et al. Multinational assessment of accuracy of equations for predicting risk of kidney failure: a meta-analysis. JAMA. 2016;315(2):164-174.
2. Tangri N, Stevens LA, Griffith J, et al. A predictive model for progression of chronic kidney disease to kidney failure. JAMA. 2011;305(15):1553-1559.
3. National Kidney Foundation. Renal Replacement Therapy: What the PCP Needs to Know. www.kidney.org/sites/default/files/PCP%20in%20a%20Box%20-%20Module%203.pptx. Accessed December 5, 2016.

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Clinician Reviews in partnership with

Renal Consult is edited by Jane S. Davis, CRNP, DNP, a member of the Clinician Reviews editorial board, who is a nurse practitioner in the Division of Nephrology at the University of Alabama at Birmingham and is the communications chairperson for the National Kidney Foundation’s Council of Advanced Practitioners (NKF-CAP); and Kim Zuber, PA-C, MSPS, DFAAPA, a semi-retired PA who works with the American Academy of Nephrology PAs and is a past chair of the NKF-CAP. This month’s responses were authored by Nicole D. McCormick, MS, MBA, NP-C, CCTC, who practices at the University of Colorado Renal Transplant Clinic in Aurora, Colorado, and Mary Rogers Sorey, MSN, who is an Assistant in Medicine in the Division of Nephrology and Hypertension at Vanderbilt University Medical Center, Nashville.

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Renal Consult is edited by Jane S. Davis, CRNP, DNP, a member of the Clinician Reviews editorial board, who is a nurse practitioner in the Division of Nephrology at the University of Alabama at Birmingham and is the communications chairperson for the National Kidney Foundation’s Council of Advanced Practitioners (NKF-CAP); and Kim Zuber, PA-C, MSPS, DFAAPA, a semi-retired PA who works with the American Academy of Nephrology PAs and is a past chair of the NKF-CAP. This month’s responses were authored by Nicole D. McCormick, MS, MBA, NP-C, CCTC, who practices at the University of Colorado Renal Transplant Clinic in Aurora, Colorado, and Mary Rogers Sorey, MSN, who is an Assistant in Medicine in the Division of Nephrology and Hypertension at Vanderbilt University Medical Center, Nashville.

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Renal Consult is edited by Jane S. Davis, CRNP, DNP, a member of the Clinician Reviews editorial board, who is a nurse practitioner in the Division of Nephrology at the University of Alabama at Birmingham and is the communications chairperson for the National Kidney Foundation’s Council of Advanced Practitioners (NKF-CAP); and Kim Zuber, PA-C, MSPS, DFAAPA, a semi-retired PA who works with the American Academy of Nephrology PAs and is a past chair of the NKF-CAP. This month’s responses were authored by Nicole D. McCormick, MS, MBA, NP-C, CCTC, who practices at the University of Colorado Renal Transplant Clinic in Aurora, Colorado, and Mary Rogers Sorey, MSN, who is an Assistant in Medicine in the Division of Nephrology and Hypertension at Vanderbilt University Medical Center, Nashville.

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Q)When I diagnose patients with minor kidney disease, they often ask if they will require dialysis. I know it is unlikely, but I wish I could give them a better answer. Can you help me?

 

The diagnosis of chronic kidney disease (CKD) is understandably concerning for many patients. Being able to estimate CKD progression helps patients gain a better understanding of their condition while allowing clinicians to develop more personalized care plans. Tangri and colleagues developed a model that can be used to predict risk for kidney failure requiring dialysis or transplantation in patients with stage III to V CKD. This model has been validated in multiple diverse populations in North America and worldwide.1

The Kidney Failure Risk Equation (found at www.kidneyfailurerisk.com) uses four variables—age, gender, glomerular filtration rate (GFR), and urine albumin-to-creatinine ratio (ACR)—to assess two- and five-year risk for kidney failure.1,2 For example

  • A 63-year-old woman with a GFR of 45 mL/min and an ACR of 30 mg/g has a 0.4% two-year risk and a 1.3% five-year risk for progression to kidney failure requiring dialysis or transplant.1
  • Alternatively, a 55-year-old man with a GFR of 38 mL/min and an ACR of 150 mg/g has a 2.9% two-year risk and a 9% five-year risk for progression to end-stage renal disease (ESRD).1
 

 

 

Per proposed thresholds, patients with a score < 5% would be deemed “low risk”; with scores of 5% to 15%, “intermediate risk”; and with scores > 15%, “high risk.”1,2

The Kidney Failure Risk Equation can be incorporated into clinic visits to provide context for lab results. For patients with low risk for progression, optimal care and lifestyle measures can be reinforced. For those with intermediate or high risk, more intensive treatments and appropriate referrals can be initiated. (The National Kidney Foundation advises referral when a patient’s estimated GFR is 20 mL/min or the urine ACR is ≥ 300 mg/g.3) Providing a numeric risk for progression can help alleviate the patient’s uncertainty surrounding the diagnosis of CKD. —NDM

Nicole D. McCormick, MS, MBA, NP-C, CCTC
University of Colorado Renal Transplant Clinic, Aurora, Colorado

Q)When I diagnose patients with minor kidney disease, they often ask if they will require dialysis. I know it is unlikely, but I wish I could give them a better answer. Can you help me?

 

The diagnosis of chronic kidney disease (CKD) is understandably concerning for many patients. Being able to estimate CKD progression helps patients gain a better understanding of their condition while allowing clinicians to develop more personalized care plans. Tangri and colleagues developed a model that can be used to predict risk for kidney failure requiring dialysis or transplantation in patients with stage III to V CKD. This model has been validated in multiple diverse populations in North America and worldwide.1

The Kidney Failure Risk Equation (found at www.kidneyfailurerisk.com) uses four variables—age, gender, glomerular filtration rate (GFR), and urine albumin-to-creatinine ratio (ACR)—to assess two- and five-year risk for kidney failure.1,2 For example

  • A 63-year-old woman with a GFR of 45 mL/min and an ACR of 30 mg/g has a 0.4% two-year risk and a 1.3% five-year risk for progression to kidney failure requiring dialysis or transplant.1
  • Alternatively, a 55-year-old man with a GFR of 38 mL/min and an ACR of 150 mg/g has a 2.9% two-year risk and a 9% five-year risk for progression to end-stage renal disease (ESRD).1
 

 

 

Per proposed thresholds, patients with a score < 5% would be deemed “low risk”; with scores of 5% to 15%, “intermediate risk”; and with scores > 15%, “high risk.”1,2

The Kidney Failure Risk Equation can be incorporated into clinic visits to provide context for lab results. For patients with low risk for progression, optimal care and lifestyle measures can be reinforced. For those with intermediate or high risk, more intensive treatments and appropriate referrals can be initiated. (The National Kidney Foundation advises referral when a patient’s estimated GFR is 20 mL/min or the urine ACR is ≥ 300 mg/g.3) Providing a numeric risk for progression can help alleviate the patient’s uncertainty surrounding the diagnosis of CKD. —NDM

Nicole D. McCormick, MS, MBA, NP-C, CCTC
University of Colorado Renal Transplant Clinic, Aurora, Colorado

References

1. Tangri N, Grams ME, Levey AS, et al. Multinational assessment of accuracy of equations for predicting risk of kidney failure: a meta-analysis. JAMA. 2016;315(2):164-174.
2. Tangri N, Stevens LA, Griffith J, et al. A predictive model for progression of chronic kidney disease to kidney failure. JAMA. 2011;305(15):1553-1559.
3. National Kidney Foundation. Renal Replacement Therapy: What the PCP Needs to Know. www.kidney.org/sites/default/files/PCP%20in%20a%20Box%20-%20Module%203.pptx. Accessed December 5, 2016.

References

1. Tangri N, Grams ME, Levey AS, et al. Multinational assessment of accuracy of equations for predicting risk of kidney failure: a meta-analysis. JAMA. 2016;315(2):164-174.
2. Tangri N, Stevens LA, Griffith J, et al. A predictive model for progression of chronic kidney disease to kidney failure. JAMA. 2011;305(15):1553-1559.
3. National Kidney Foundation. Renal Replacement Therapy: What the PCP Needs to Know. www.kidney.org/sites/default/files/PCP%20in%20a%20Box%20-%20Module%203.pptx. Accessed December 5, 2016.

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Pulmonary embolism in COPD exacerbations

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Clinical question: How frequent is pulmonary embolism (PE) in patients with unexplained acute chronic obstructive pulmonary disease (COPD) exacerbation?

Background: Acute COPD exacerbations are highly inflammatory states, and since there is a well-known interaction between inflammatory pathways and thrombosis, PE occurs with increased prevalence, ranging from 18% to 25%. In approximately 30% of cases of acute exacerbations of COPD, no clear etiology is found.

Study design: Systematic review.

Setting: U.S. hospitals and EDs.

Synopsis: PE prevalence was 16.1% (95% CI, 8.3%-25.8%) in patients with unexplained COPD exacerbations. Thirty-two percent were subsegmental, 35% affected one of the main pulmonary arteries, and 32% were located in the lobar and interlobar arteries. Heterogeneity between the included studies was high. In-hospital and 1-year mortality were increased in patients with PE and COPD exacerbations in one study but not in another.

Signs of cardiac failure, hypotension, and syncope were more frequently found in patients with COPD exacerbation and PE, compared with patients with COPD exacerbation without PE.

Bottom line: PE is a common occurrence in patients with unexplained COPD exacerbations; two-thirds of those emboli involved segmental circulation and therefore were clinically relevant.

Citation: Aleva FE, Voets LW, Simons SO, de Mast Q, van der Ven A, Heijdra YF. Prevalence and localization of pulmonary embolism in unexplained acute exacerbations of COPD: a systematic review and meta-analysis [published online ahead of print Aug. 11, 2016]. Chest. doi: 10.1016/j.chest.2016.07.034.

Dr. Giese is an assistant professor at the University of Miami Miller School of Medicine and a hospitalist at the University of Miami Hospital and Jackson Memorial Hospital.
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Clinical question: How frequent is pulmonary embolism (PE) in patients with unexplained acute chronic obstructive pulmonary disease (COPD) exacerbation?

Background: Acute COPD exacerbations are highly inflammatory states, and since there is a well-known interaction between inflammatory pathways and thrombosis, PE occurs with increased prevalence, ranging from 18% to 25%. In approximately 30% of cases of acute exacerbations of COPD, no clear etiology is found.

Study design: Systematic review.

Setting: U.S. hospitals and EDs.

Synopsis: PE prevalence was 16.1% (95% CI, 8.3%-25.8%) in patients with unexplained COPD exacerbations. Thirty-two percent were subsegmental, 35% affected one of the main pulmonary arteries, and 32% were located in the lobar and interlobar arteries. Heterogeneity between the included studies was high. In-hospital and 1-year mortality were increased in patients with PE and COPD exacerbations in one study but not in another.

Signs of cardiac failure, hypotension, and syncope were more frequently found in patients with COPD exacerbation and PE, compared with patients with COPD exacerbation without PE.

Bottom line: PE is a common occurrence in patients with unexplained COPD exacerbations; two-thirds of those emboli involved segmental circulation and therefore were clinically relevant.

Citation: Aleva FE, Voets LW, Simons SO, de Mast Q, van der Ven A, Heijdra YF. Prevalence and localization of pulmonary embolism in unexplained acute exacerbations of COPD: a systematic review and meta-analysis [published online ahead of print Aug. 11, 2016]. Chest. doi: 10.1016/j.chest.2016.07.034.

Dr. Giese is an assistant professor at the University of Miami Miller School of Medicine and a hospitalist at the University of Miami Hospital and Jackson Memorial Hospital.

 

Clinical question: How frequent is pulmonary embolism (PE) in patients with unexplained acute chronic obstructive pulmonary disease (COPD) exacerbation?

Background: Acute COPD exacerbations are highly inflammatory states, and since there is a well-known interaction between inflammatory pathways and thrombosis, PE occurs with increased prevalence, ranging from 18% to 25%. In approximately 30% of cases of acute exacerbations of COPD, no clear etiology is found.

Study design: Systematic review.

Setting: U.S. hospitals and EDs.

Synopsis: PE prevalence was 16.1% (95% CI, 8.3%-25.8%) in patients with unexplained COPD exacerbations. Thirty-two percent were subsegmental, 35% affected one of the main pulmonary arteries, and 32% were located in the lobar and interlobar arteries. Heterogeneity between the included studies was high. In-hospital and 1-year mortality were increased in patients with PE and COPD exacerbations in one study but not in another.

Signs of cardiac failure, hypotension, and syncope were more frequently found in patients with COPD exacerbation and PE, compared with patients with COPD exacerbation without PE.

Bottom line: PE is a common occurrence in patients with unexplained COPD exacerbations; two-thirds of those emboli involved segmental circulation and therefore were clinically relevant.

Citation: Aleva FE, Voets LW, Simons SO, de Mast Q, van der Ven A, Heijdra YF. Prevalence and localization of pulmonary embolism in unexplained acute exacerbations of COPD: a systematic review and meta-analysis [published online ahead of print Aug. 11, 2016]. Chest. doi: 10.1016/j.chest.2016.07.034.

Dr. Giese is an assistant professor at the University of Miami Miller School of Medicine and a hospitalist at the University of Miami Hospital and Jackson Memorial Hospital.
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Have you Googled yourself lately?

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With a majority of patients relying on physician ratings, hospitalists might consider countermeasures.

The online rating business is proliferating in the medical industry. This should really come as no surprise as health care is a service industry and online ratings have long been a staple in most other service industries. It has become routine practice for most of us to search such online reviews when seeking a pair of shoes, a toaster, or a restaurant; we almost can’t help but scour these sites to help us make the best decision possible.

Dr. Danielle Scheurer
Many of these reviews come in quantitative and qualitative forms, for example, stars or numerical ratings, along with qualitative comments. Of course, when seeking out products and services, these ratings are not usually the sole mechanism that we use to make decisions. For example, with the toaster analogy, I would not only be influenced by the reviews but also by the cost and the accessibility of the toaster (for example, when I can get it shipped or if it is available in a nearby store).

Not dissimilarly, patients these days seek care and make decisions by using a variety of inputs, including:
  • Anticipated cost (is the physician or practice in or out of network?).
  • Availability or access to the service (location of the practice and how long it will take to be seen).
  • How good the services and care will be when they get there.

A study in JAMA found the top two factors influencing the selection of physicians were whether they accept a patient’s insurance and whether their location is convenient.1 But the study also found that 59% of American adults considered online ratings “somewhat important” or “very important” when choosing physicians.

That same article found that for those who used online physician ratings, about one-third had selected a physician based on good ratings, and about one-third had avoided a physician based on poor ratings. So patients do seem to be paying attention to these sites and seeking or avoiding care based on what information they find.

Based on that evidence, it is not surprising that so many physician rating sites have sprung up; not only is there a market demand for the availability of this information, the rating sites are also profitable for the host companies. Vitals.com, for example, makes most of its revenue from advertisements and turns a sizable profit every year. Other profitable health care rating sites include Healthgrades, Yelp, Zocdoc, and WebMD.

When I Google my own name, for example, Vitals.com is the first ratings website that appears in the search results. The first pop-up asks you to rate me and then it takes you to a site with all sorts of facts about me (most of which are notably inaccurate). If I had any online ratings (which I do not currently), you would then see my star ratings and any comments.

The second rating site that comes up for me via Google search is PhysicianWiki.com.There is a whole host of information on me (most of which is accurate), along with a set of personal ratings, including my office, my staff, and my waiting times (which, of course, do not make any sense given I am a hospitalist!). It is unclear how those ratings were generated or what volume of responses they represent.

Because of such limitations with the online rating business for physicians, some health care systems have tried to “take control of the conversation” by posting their own internally collected quantitative and qualitative feedback from patients. The University of Utah was one of the first in the nation to create its own internal site for star ratings and comments.2 What you see on its site is detailed information about the physicians (clinical profile, academic profile, education, contact information, etc.), their patient ratings on nine different questions (displayed as star ratings), the number of total ratings, and a line listing of patient comments (ordered by date). Such sites have proliferated among many health care systems in the past few years primarily to take control of the conversation and to not cede patient decision making to third-party sites.

My health care system proposed rolling out a similar online rating system, and it was met with great skepticism from many physicians. There were two primary concerns:

  • They felt it was “tacky” and that the profession of medicine should not be relegated to oversimplified service ratings. They worried that they would feel pressured to please the patient rather than “do the right thing” for the patient. For example, they would be less likely to give difficult advice (such as lose weight or stop smoking) or to resist prescribing medications that they deemed unnecessary or frankly dangerous (for example, antibiotics or narcotics).
 

 

Although these are valid concerns, it is hard to ignore the proliferation and traffic of these online websites. For you and your team, I would recommend taking a look at what is online about the members of your group and thinking about online strategies to take control of the conversation.

I don’t think the controversy over online physician ratings will wane anytime soon, but there is no doubt that they are profitable for companies and are therefore highly likely to continue to multiply.

References

1.Hanauer DA, Zheng K, Singer DC, Gebremariam A, Davis MM. Public awareness, perception, and use of online physician rating sites. JAMA. 2014;311(7):734-735. 2. A to Z provider listing: find a U of U Health Care physician by last name. University of Utah website. Available at http://healthcare.utah.edu/fad. Accessed Nov. 16, 2016.

Danielle Scheurer, MD, MSc, SFHM, is a hospitalist and chief quality officer at the Medical University of South Carolina in Charleston. She is physician editor of The Hospitalist. Email her at [email protected].

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With a majority of patients relying on physician ratings, hospitalists might consider countermeasures.
With a majority of patients relying on physician ratings, hospitalists might consider countermeasures.

The online rating business is proliferating in the medical industry. This should really come as no surprise as health care is a service industry and online ratings have long been a staple in most other service industries. It has become routine practice for most of us to search such online reviews when seeking a pair of shoes, a toaster, or a restaurant; we almost can’t help but scour these sites to help us make the best decision possible.

Dr. Danielle Scheurer
Many of these reviews come in quantitative and qualitative forms, for example, stars or numerical ratings, along with qualitative comments. Of course, when seeking out products and services, these ratings are not usually the sole mechanism that we use to make decisions. For example, with the toaster analogy, I would not only be influenced by the reviews but also by the cost and the accessibility of the toaster (for example, when I can get it shipped or if it is available in a nearby store).

Not dissimilarly, patients these days seek care and make decisions by using a variety of inputs, including:
  • Anticipated cost (is the physician or practice in or out of network?).
  • Availability or access to the service (location of the practice and how long it will take to be seen).
  • How good the services and care will be when they get there.

A study in JAMA found the top two factors influencing the selection of physicians were whether they accept a patient’s insurance and whether their location is convenient.1 But the study also found that 59% of American adults considered online ratings “somewhat important” or “very important” when choosing physicians.

That same article found that for those who used online physician ratings, about one-third had selected a physician based on good ratings, and about one-third had avoided a physician based on poor ratings. So patients do seem to be paying attention to these sites and seeking or avoiding care based on what information they find.

Based on that evidence, it is not surprising that so many physician rating sites have sprung up; not only is there a market demand for the availability of this information, the rating sites are also profitable for the host companies. Vitals.com, for example, makes most of its revenue from advertisements and turns a sizable profit every year. Other profitable health care rating sites include Healthgrades, Yelp, Zocdoc, and WebMD.

When I Google my own name, for example, Vitals.com is the first ratings website that appears in the search results. The first pop-up asks you to rate me and then it takes you to a site with all sorts of facts about me (most of which are notably inaccurate). If I had any online ratings (which I do not currently), you would then see my star ratings and any comments.

The second rating site that comes up for me via Google search is PhysicianWiki.com.There is a whole host of information on me (most of which is accurate), along with a set of personal ratings, including my office, my staff, and my waiting times (which, of course, do not make any sense given I am a hospitalist!). It is unclear how those ratings were generated or what volume of responses they represent.

Because of such limitations with the online rating business for physicians, some health care systems have tried to “take control of the conversation” by posting their own internally collected quantitative and qualitative feedback from patients. The University of Utah was one of the first in the nation to create its own internal site for star ratings and comments.2 What you see on its site is detailed information about the physicians (clinical profile, academic profile, education, contact information, etc.), their patient ratings on nine different questions (displayed as star ratings), the number of total ratings, and a line listing of patient comments (ordered by date). Such sites have proliferated among many health care systems in the past few years primarily to take control of the conversation and to not cede patient decision making to third-party sites.

My health care system proposed rolling out a similar online rating system, and it was met with great skepticism from many physicians. There were two primary concerns:

  • They felt it was “tacky” and that the profession of medicine should not be relegated to oversimplified service ratings. They worried that they would feel pressured to please the patient rather than “do the right thing” for the patient. For example, they would be less likely to give difficult advice (such as lose weight or stop smoking) or to resist prescribing medications that they deemed unnecessary or frankly dangerous (for example, antibiotics or narcotics).
 

 

Although these are valid concerns, it is hard to ignore the proliferation and traffic of these online websites. For you and your team, I would recommend taking a look at what is online about the members of your group and thinking about online strategies to take control of the conversation.

I don’t think the controversy over online physician ratings will wane anytime soon, but there is no doubt that they are profitable for companies and are therefore highly likely to continue to multiply.

References

1.Hanauer DA, Zheng K, Singer DC, Gebremariam A, Davis MM. Public awareness, perception, and use of online physician rating sites. JAMA. 2014;311(7):734-735. 2. A to Z provider listing: find a U of U Health Care physician by last name. University of Utah website. Available at http://healthcare.utah.edu/fad. Accessed Nov. 16, 2016.

Danielle Scheurer, MD, MSc, SFHM, is a hospitalist and chief quality officer at the Medical University of South Carolina in Charleston. She is physician editor of The Hospitalist. Email her at [email protected].

The online rating business is proliferating in the medical industry. This should really come as no surprise as health care is a service industry and online ratings have long been a staple in most other service industries. It has become routine practice for most of us to search such online reviews when seeking a pair of shoes, a toaster, or a restaurant; we almost can’t help but scour these sites to help us make the best decision possible.

Dr. Danielle Scheurer
Many of these reviews come in quantitative and qualitative forms, for example, stars or numerical ratings, along with qualitative comments. Of course, when seeking out products and services, these ratings are not usually the sole mechanism that we use to make decisions. For example, with the toaster analogy, I would not only be influenced by the reviews but also by the cost and the accessibility of the toaster (for example, when I can get it shipped or if it is available in a nearby store).

Not dissimilarly, patients these days seek care and make decisions by using a variety of inputs, including:
  • Anticipated cost (is the physician or practice in or out of network?).
  • Availability or access to the service (location of the practice and how long it will take to be seen).
  • How good the services and care will be when they get there.

A study in JAMA found the top two factors influencing the selection of physicians were whether they accept a patient’s insurance and whether their location is convenient.1 But the study also found that 59% of American adults considered online ratings “somewhat important” or “very important” when choosing physicians.

That same article found that for those who used online physician ratings, about one-third had selected a physician based on good ratings, and about one-third had avoided a physician based on poor ratings. So patients do seem to be paying attention to these sites and seeking or avoiding care based on what information they find.

Based on that evidence, it is not surprising that so many physician rating sites have sprung up; not only is there a market demand for the availability of this information, the rating sites are also profitable for the host companies. Vitals.com, for example, makes most of its revenue from advertisements and turns a sizable profit every year. Other profitable health care rating sites include Healthgrades, Yelp, Zocdoc, and WebMD.

When I Google my own name, for example, Vitals.com is the first ratings website that appears in the search results. The first pop-up asks you to rate me and then it takes you to a site with all sorts of facts about me (most of which are notably inaccurate). If I had any online ratings (which I do not currently), you would then see my star ratings and any comments.

The second rating site that comes up for me via Google search is PhysicianWiki.com.There is a whole host of information on me (most of which is accurate), along with a set of personal ratings, including my office, my staff, and my waiting times (which, of course, do not make any sense given I am a hospitalist!). It is unclear how those ratings were generated or what volume of responses they represent.

Because of such limitations with the online rating business for physicians, some health care systems have tried to “take control of the conversation” by posting their own internally collected quantitative and qualitative feedback from patients. The University of Utah was one of the first in the nation to create its own internal site for star ratings and comments.2 What you see on its site is detailed information about the physicians (clinical profile, academic profile, education, contact information, etc.), their patient ratings on nine different questions (displayed as star ratings), the number of total ratings, and a line listing of patient comments (ordered by date). Such sites have proliferated among many health care systems in the past few years primarily to take control of the conversation and to not cede patient decision making to third-party sites.

My health care system proposed rolling out a similar online rating system, and it was met with great skepticism from many physicians. There were two primary concerns:

  • They felt it was “tacky” and that the profession of medicine should not be relegated to oversimplified service ratings. They worried that they would feel pressured to please the patient rather than “do the right thing” for the patient. For example, they would be less likely to give difficult advice (such as lose weight or stop smoking) or to resist prescribing medications that they deemed unnecessary or frankly dangerous (for example, antibiotics or narcotics).
 

 

Although these are valid concerns, it is hard to ignore the proliferation and traffic of these online websites. For you and your team, I would recommend taking a look at what is online about the members of your group and thinking about online strategies to take control of the conversation.

I don’t think the controversy over online physician ratings will wane anytime soon, but there is no doubt that they are profitable for companies and are therefore highly likely to continue to multiply.

References

1.Hanauer DA, Zheng K, Singer DC, Gebremariam A, Davis MM. Public awareness, perception, and use of online physician rating sites. JAMA. 2014;311(7):734-735. 2. A to Z provider listing: find a U of U Health Care physician by last name. University of Utah website. Available at http://healthcare.utah.edu/fad. Accessed Nov. 16, 2016.

Danielle Scheurer, MD, MSc, SFHM, is a hospitalist and chief quality officer at the Medical University of South Carolina in Charleston. She is physician editor of The Hospitalist. Email her at [email protected].

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Alternative CME

In Memoriam

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CHEST has been informed of the following members’ deaths. We extend our sincere condolences.

Anthony Cosentino, MD, FCCP (January 2016)

Ben Branscomb, MD (July 2016)

Steven Sahn, MD, FCCP (Aug 2016)

Thomas Aldrich, MD (September 2016)

John C. Baldwin, MD, FCCP (September 2016)

David Cugell, MD, FCCP (December 2016)

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CHEST has been informed of the following members’ deaths. We extend our sincere condolences.

Anthony Cosentino, MD, FCCP (January 2016)

Ben Branscomb, MD (July 2016)

Steven Sahn, MD, FCCP (Aug 2016)

Thomas Aldrich, MD (September 2016)

John C. Baldwin, MD, FCCP (September 2016)

David Cugell, MD, FCCP (December 2016)

 

CHEST has been informed of the following members’ deaths. We extend our sincere condolences.

Anthony Cosentino, MD, FCCP (January 2016)

Ben Branscomb, MD (July 2016)

Steven Sahn, MD, FCCP (Aug 2016)

Thomas Aldrich, MD (September 2016)

John C. Baldwin, MD, FCCP (September 2016)

David Cugell, MD, FCCP (December 2016)

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Winners-All at CHEST 2016

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We all know that, with the great success of CHEST 2016, everyone who shared that event is a winner. But, we would especially like to call out some of the special winners who were recognized during our annual meeting.

CHEST Awards

College Medalist Award

Lewis J. Rubin, MD, FCCP

Distinguished Service Award

Kim D. French, MHSA, CAPPM, FCCP

Alfred Soffer Award for Editorial Excellence

Seth J. Koenig, MD, FCCP

Master Clinician Educator Award

Jack D. Buckley, MD, MPH, FCCP

Distinguished Scientist Honor Lecture

Jay Nadel, MD

Edward C. Rosenow III, MD, Master FCCP/Master Teacher Honor Lecture

Suhail Raoof, MBBS, FCCP

Murray Kornfeld Memorial Founders Lecture

Michael Niederman, MD, FCCP Pasquale Ciaglia Memorial Lecture Kevin L. Kovitz, MD, FCCP

Roger C. Bone Memorial Lecture

Robert A. Berg, MD Thomas L. Petty, MD, Master FCCP Memorial Lecture Nicola A. Hanania, MD, MS, FCCP Margaret Pfrommer Memorial Lecture in Long-term Mechanical Ventilation Thomas G. Keens, MD Om P. Sharma, MD, Master FCCP Memorial Lecture Robert P. Baughman, MD, FCCP

Early Career Educator

Gabriel Bosslet, MD, FCCP

CHEST Challenge Championship 2016

1st Place

The University of Arizona

Huthayfa Ateeli, MBBS Naser Mahmoud, MD

Muna Omar, MD, MBBS


PD: James L. Knepler Jr.

2nd Place

New York Methodist Hospital

Anu R. Jacob, MD

Stephen D. Milan, MD

Jordan Taillon, MD


PD: Anthony G. Saleh, MD, FCCP

3rd Place

Interfaith Medical Center

Chidozie C. Agu, MD

Saroj P. Kandel, MBBS
Divya Salhan, MD, MBBS

PD: Marie Frances J. Schmidt, MD, FCCP

CHEST Foundation Grant Winners

GlaxoSmithKline Distinguished Scholar in Respiratory Health

Don Hayes Jr., MD, FCCP The Research Institute at Nationwide Children’s Hospital

Implications of the Lung Allocation Score in Prioritizing Critically Ill Patients for Lung Transplantation

Supported by GlaxoSmithKline.

2016 Research Grantees

Alice Turner, MBChB, MRCP, PhD

University of Birmingham, United Kingdom

CHEST Foundation and the Alpha-1 Foundation Research Grant in Alpha-1 Antitrypsin Deficiency

Improving Access to Augmentation: A Propensity-Matching Study Between the UK AATD Registry and AlphaNet

This grant is jointly supported by the CHEST Foundation and the Alpha-1 Foundation.

Robert Busch, MD

Brigham and Women’s Hospital, Channing Division of Network Medicine

CHEST Foundation Research Grant in Chronic Obstructive Pulmonary Disease

Methylation Quantitative Trait Loci: Markers of Race-Specific Disparities in African Americans With COPD

This grant is supported by AstraZeneca.

Clemens Grassberger, PhD

Massachusetts General Hospital – Harvard University

CHEST Foundation Research Grant in Lung Cancer

Dynamic FLT-PET as Biomarker for Early Response in Locally Advanced Lung Cancer Patients

This grant is supported by Genentech Inc.

 

 

Cristina Russo, MD, PhD

Bambino Gesù Children’s Hospital, Rome, Italy

CHEST Foundation Research Grant in Nontuberculous Mycobacteria

A Proteomic-Metaproteomic Analysis Approach Allows Identification of Drug Target Candidates for the Future Design of Preventive, Diagnostic, and Therapeutic Strategies Against Nontuberculous Mycobacteria Diseases

This grant is supported by Insmed.

Peter Leary, MD, MS

University of Washington

CHEST Foundation Research Grant in Pulmonary Arterial Hypertension

Expression Profiling in Pulmonary Arterial Hypertension

This grant is supported by Actelion Pharmaceuticals, US, Inc.

Brett Ley, MD

University of California, San Francisco

CHEST Foundation Research Grant in Pulmonary Fibrosis

Extracellular Circulation RNAs as Predictors of Disease Progression in Idiopathic Pulmonary Fibrosis

This grant is supported by Boehringer Ingelheim Pharmaceuticals & Genentech Inc.

Sydney Montesi, MD

Massachusetts General Hospital

CHEST Foundation Research Grant in Pulmonary Fibrosis

Gadofosveset-Enhanced Lung MRI to Detect Idiopathic Pulmonary Fibrosis Disease Activity

This grant is supported by Boehringer Ingelheim Pharmaceuticals & Genentech Inc.

Farbod Rahaghi, MD, PhD

Brigham and Women’s Hospital

CHEST Foundation Research Grant in Venous Thromboembolism

CT Scan-Based Markers for Prediction of Outcomes in Acute Pulmonary Embolism

This grant is supported by Daiichi Sankyo.

Catherine Oberg, MD

Icahn School of Medicine at Mount Sinai

CHEST Foundation Research Grant in Women’s Lung Health

Effects of Household Air Pollution on Airway Inflammation, Lung Function, and Respiratory Symptoms

This grant is supported in full by the CHEST Foundation.

2016 Community Service Grantee

Ethel Jane Carter, MD, FCCP

Warren Alpert School of Medicine at Brown University

CHEST Foundation Community Service Grant Honoring D. Robert McCaffree, MD, Master FCCP

East African Training Initiative ( EATI) in Pulmonary Medicine

2016 NetWorks Challenge Travel Grantees

Debarsee Banerjee, MS, MD

Women’s Health NetWork

Drew Harris, MD

Occupational and Environmental Health NetWork

Kerry Hena, MD

Occupational and Environmental Health NetWork

Amanpreet Kaur, MD

Women’s Health NetWork

2016 Diversity Travel Grant Winners

John B. Bishara, DO

Renato F. Blanco Jr., MD

Angel Coz-Yataco, MD
Sherie A. Gause, MD

Anthony Nebor, MD

James T. Williams, MD



Alfred Soffer Research Award Winners

Kerry Hena, MD

Deepak Pradhan, MD, FCCP

Young Investigator Award Winners

Elizabeth Becker: Clinical Characteristics of Sarcoidosis in World Trade Center (WTC) Exposed Fire Department of the City of New York (FDNY) Firefighters

Daniel Altman, MD : Cost-Effectiveness of Universally Funding Smoking Cessation Pharmacotherapy

Top 3 Poster Winners

Epaminondas Kosmas, MD, PhD, FCCP : Bronchiectasis in Patients With COPD: An Irrelevant Imaging Finding or a Clinically Important Phenotype?

Mark Regala, MD, BS : Evaluation of Outcomes of Post-Extubation Dysphagia in Elderly Patients

Massa Zantah, MD : Correlation of Esophageal Dilatation and Pulmonary Fibrosis in Scleroderma

Runner-up: Alev Gurgun, MD : Pulmonary Rehabilitation Response in Elderly and Younger Patients With COPD

Case Report Slide Winners

John Egan, MD, BA : An Unusual Cause of Tracheal Stenosis Due to a Vascular Anomaly Successfully Managed With Silicone Airway Stenting Prior to Definitive Vascular Repair

Harprett Grewal, MD : Bladder PTLD: First Reported Case of Post-Transplant Lymphoproliferative Disorder (PTLD) in the Bladder in a Lung Transplant Recipient

Michael Fingerhood, MD, MPH : Pulmonary Overlap Histiocytosis: A Rare Case of Interstitial Lung Disease Due to Erdheim Chester Disease in a Patient With Langerhans Cell Histiocytosis and Myelodisplastic Syndrome

Yihenew Negatu, MD : Acute ST Elevation Myocardial Infarction Related to Carbon Monoxide Poisoning in a Young Patient Without Coronary Artery Disease

Stephanie Wappel, MD : False-Negative Pet Imaging in Early Stage Malignant Pleural Mesothelioma

Lina Miyakawa, MD : Restrictive EGFR Mutation

Jeffrey Bonenfant, DO : A Unique Case of Follicular Bronchiolitis

Melissa Myers, MD : Seeing the Forest and Not Just the Trees: A Case of Recurrent Fever, Cough, and Respiratory Failure

Carly Fabrizio, DO : An Unusual Case of Submassive Hemoptysis

Meilinh Thi, DO : A Case to Make Your Skin Crawl

Garrett Harp, MD : Lambertosis: A Lung Cancer Mimic

Malik Khan, MD : Pleural Epithelioid Hemangioendothelioma: A Case Report

Priya Patel, MD : A Troubling Trifecta: Pulmonary Alveolar Proteinosis and Pneumocystis Pneumonia in Acute Myeloid Leukemia

Atul Palkar, MD : SGLT2 Inhibitors: Mind the Gap

Ji Yeon Lee, MD : Making Unusual Connections: Fibrosing Mediastinitis Leading to Bronchoesophageal Fistula

Sailm Daouk, MD : A Rare Form of Invasive Aspergillus Infection in a Severely Immunocompromised Host

Venkata Ravi Kumar Angirekula, MD : Vanishing Lung

Stephen Milan, MD : An Unexpected Mass

Lelia Logue, MD : A Rare Cause of Dysphagia

Daniel Hershberger, MD : Rapidly Progressive Hypoxic Respiratory Failure After a Rash: A Case of Clinically Amyopathic Dermatomyositis (CADM)-Associated ILD

 

 

Fellow Case Report Poster Winners

Krishna Siva Sai Kakkera

An Unusual Case of Crypotococcal Pleural Effusion

George Cheng

Use of Laparoscopic Suction Irrigator With Rigid Pleuroscope in Medical Thoracoscopy

Matt Koroscil

Wong Type Dermatomyositis Complicated by Interstitial Lung Disease

Derek Hansen

Acute Fibrinous and Organizing Pneumonia Following Hematopoietic Stem Cell Transplantation Responsive to Corticosteroid Therapy

Ala Eddin Sagar

Pulmonary Embolism Caused by Thrombin-Based Hemostatic Matrix After Discectomy

Sandeep Chennadi

Systemic Lupus Erythematosus (SLE) With Refractory Bilateral Chylothorax and Chylous Ascites

Medical Student/Resident Case Report Poster Winners

Justin Fiala

Pulmonary Presentation Without Concurrent Bone Involvement in Erdheim-Chester Disease: A Report of Two Cases

Navitha Ramesh

A Fatal Migration: A Case of Intra-Cardiac Embolization of a Peripheral Stent

Humna Abid Memon

Use of Extracorporeal Membrane Oxygenation in Postpartum Management of a Patient With PAH

Vanessa Ohleyer

A Case of Unusual Anatomy for an Uncommon Mediastinal Tumor

Tanushree Gahlot

Three Unusual Presentations of Job’s Syndrome (Hyper Immunoglobulin E Syndrome)

NetWorks Challenge Winners

Round 1

Women’s Lung Health NetWork

Round 2

Practice and Operations NetWork-1st place

Home-Based Mechanical Ventilation and Neuromuscular Disease NetWorks – 2nd place

Round 3

Home-Based Mechanical Ventilation, Neuromuscular Disease, and the Women’s Lung Health NetWorks

CHEST Bingo Winners

Youseff Anid, MD, FCCP

Karen Cochran, ACNP

Molly Howsware, DO

Katie Jeans, MD

Genovena Medina, RN

Gregory Eisinger, MD

Saurabh Mittal, MD, MBBS

Navitha Ramesh, MD

Dalvinder Dhillon, MD

Teresita Saylor, MD, FCCP

Carl Kaplan, MD, FCCP

Vishal Patel, MBBS, FCCP

Erin Peterson, CNP

Lilian Pereira, DO

Publications
Topics
Sections

 

We all know that, with the great success of CHEST 2016, everyone who shared that event is a winner. But, we would especially like to call out some of the special winners who were recognized during our annual meeting.

CHEST Awards

College Medalist Award

Lewis J. Rubin, MD, FCCP

Distinguished Service Award

Kim D. French, MHSA, CAPPM, FCCP

Alfred Soffer Award for Editorial Excellence

Seth J. Koenig, MD, FCCP

Master Clinician Educator Award

Jack D. Buckley, MD, MPH, FCCP

Distinguished Scientist Honor Lecture

Jay Nadel, MD

Edward C. Rosenow III, MD, Master FCCP/Master Teacher Honor Lecture

Suhail Raoof, MBBS, FCCP

Murray Kornfeld Memorial Founders Lecture

Michael Niederman, MD, FCCP Pasquale Ciaglia Memorial Lecture Kevin L. Kovitz, MD, FCCP

Roger C. Bone Memorial Lecture

Robert A. Berg, MD Thomas L. Petty, MD, Master FCCP Memorial Lecture Nicola A. Hanania, MD, MS, FCCP Margaret Pfrommer Memorial Lecture in Long-term Mechanical Ventilation Thomas G. Keens, MD Om P. Sharma, MD, Master FCCP Memorial Lecture Robert P. Baughman, MD, FCCP

Early Career Educator

Gabriel Bosslet, MD, FCCP

CHEST Challenge Championship 2016

1st Place

The University of Arizona

Huthayfa Ateeli, MBBS Naser Mahmoud, MD

Muna Omar, MD, MBBS


PD: James L. Knepler Jr.

2nd Place

New York Methodist Hospital

Anu R. Jacob, MD

Stephen D. Milan, MD

Jordan Taillon, MD


PD: Anthony G. Saleh, MD, FCCP

3rd Place

Interfaith Medical Center

Chidozie C. Agu, MD

Saroj P. Kandel, MBBS
Divya Salhan, MD, MBBS

PD: Marie Frances J. Schmidt, MD, FCCP

CHEST Foundation Grant Winners

GlaxoSmithKline Distinguished Scholar in Respiratory Health

Don Hayes Jr., MD, FCCP The Research Institute at Nationwide Children’s Hospital

Implications of the Lung Allocation Score in Prioritizing Critically Ill Patients for Lung Transplantation

Supported by GlaxoSmithKline.

2016 Research Grantees

Alice Turner, MBChB, MRCP, PhD

University of Birmingham, United Kingdom

CHEST Foundation and the Alpha-1 Foundation Research Grant in Alpha-1 Antitrypsin Deficiency

Improving Access to Augmentation: A Propensity-Matching Study Between the UK AATD Registry and AlphaNet

This grant is jointly supported by the CHEST Foundation and the Alpha-1 Foundation.

Robert Busch, MD

Brigham and Women’s Hospital, Channing Division of Network Medicine

CHEST Foundation Research Grant in Chronic Obstructive Pulmonary Disease

Methylation Quantitative Trait Loci: Markers of Race-Specific Disparities in African Americans With COPD

This grant is supported by AstraZeneca.

Clemens Grassberger, PhD

Massachusetts General Hospital – Harvard University

CHEST Foundation Research Grant in Lung Cancer

Dynamic FLT-PET as Biomarker for Early Response in Locally Advanced Lung Cancer Patients

This grant is supported by Genentech Inc.

 

 

Cristina Russo, MD, PhD

Bambino Gesù Children’s Hospital, Rome, Italy

CHEST Foundation Research Grant in Nontuberculous Mycobacteria

A Proteomic-Metaproteomic Analysis Approach Allows Identification of Drug Target Candidates for the Future Design of Preventive, Diagnostic, and Therapeutic Strategies Against Nontuberculous Mycobacteria Diseases

This grant is supported by Insmed.

Peter Leary, MD, MS

University of Washington

CHEST Foundation Research Grant in Pulmonary Arterial Hypertension

Expression Profiling in Pulmonary Arterial Hypertension

This grant is supported by Actelion Pharmaceuticals, US, Inc.

Brett Ley, MD

University of California, San Francisco

CHEST Foundation Research Grant in Pulmonary Fibrosis

Extracellular Circulation RNAs as Predictors of Disease Progression in Idiopathic Pulmonary Fibrosis

This grant is supported by Boehringer Ingelheim Pharmaceuticals & Genentech Inc.

Sydney Montesi, MD

Massachusetts General Hospital

CHEST Foundation Research Grant in Pulmonary Fibrosis

Gadofosveset-Enhanced Lung MRI to Detect Idiopathic Pulmonary Fibrosis Disease Activity

This grant is supported by Boehringer Ingelheim Pharmaceuticals & Genentech Inc.

Farbod Rahaghi, MD, PhD

Brigham and Women’s Hospital

CHEST Foundation Research Grant in Venous Thromboembolism

CT Scan-Based Markers for Prediction of Outcomes in Acute Pulmonary Embolism

This grant is supported by Daiichi Sankyo.

Catherine Oberg, MD

Icahn School of Medicine at Mount Sinai

CHEST Foundation Research Grant in Women’s Lung Health

Effects of Household Air Pollution on Airway Inflammation, Lung Function, and Respiratory Symptoms

This grant is supported in full by the CHEST Foundation.

2016 Community Service Grantee

Ethel Jane Carter, MD, FCCP

Warren Alpert School of Medicine at Brown University

CHEST Foundation Community Service Grant Honoring D. Robert McCaffree, MD, Master FCCP

East African Training Initiative ( EATI) in Pulmonary Medicine

2016 NetWorks Challenge Travel Grantees

Debarsee Banerjee, MS, MD

Women’s Health NetWork

Drew Harris, MD

Occupational and Environmental Health NetWork

Kerry Hena, MD

Occupational and Environmental Health NetWork

Amanpreet Kaur, MD

Women’s Health NetWork

2016 Diversity Travel Grant Winners

John B. Bishara, DO

Renato F. Blanco Jr., MD

Angel Coz-Yataco, MD
Sherie A. Gause, MD

Anthony Nebor, MD

James T. Williams, MD



Alfred Soffer Research Award Winners

Kerry Hena, MD

Deepak Pradhan, MD, FCCP

Young Investigator Award Winners

Elizabeth Becker: Clinical Characteristics of Sarcoidosis in World Trade Center (WTC) Exposed Fire Department of the City of New York (FDNY) Firefighters

Daniel Altman, MD : Cost-Effectiveness of Universally Funding Smoking Cessation Pharmacotherapy

Top 3 Poster Winners

Epaminondas Kosmas, MD, PhD, FCCP : Bronchiectasis in Patients With COPD: An Irrelevant Imaging Finding or a Clinically Important Phenotype?

Mark Regala, MD, BS : Evaluation of Outcomes of Post-Extubation Dysphagia in Elderly Patients

Massa Zantah, MD : Correlation of Esophageal Dilatation and Pulmonary Fibrosis in Scleroderma

Runner-up: Alev Gurgun, MD : Pulmonary Rehabilitation Response in Elderly and Younger Patients With COPD

Case Report Slide Winners

John Egan, MD, BA : An Unusual Cause of Tracheal Stenosis Due to a Vascular Anomaly Successfully Managed With Silicone Airway Stenting Prior to Definitive Vascular Repair

Harprett Grewal, MD : Bladder PTLD: First Reported Case of Post-Transplant Lymphoproliferative Disorder (PTLD) in the Bladder in a Lung Transplant Recipient

Michael Fingerhood, MD, MPH : Pulmonary Overlap Histiocytosis: A Rare Case of Interstitial Lung Disease Due to Erdheim Chester Disease in a Patient With Langerhans Cell Histiocytosis and Myelodisplastic Syndrome

Yihenew Negatu, MD : Acute ST Elevation Myocardial Infarction Related to Carbon Monoxide Poisoning in a Young Patient Without Coronary Artery Disease

Stephanie Wappel, MD : False-Negative Pet Imaging in Early Stage Malignant Pleural Mesothelioma

Lina Miyakawa, MD : Restrictive EGFR Mutation

Jeffrey Bonenfant, DO : A Unique Case of Follicular Bronchiolitis

Melissa Myers, MD : Seeing the Forest and Not Just the Trees: A Case of Recurrent Fever, Cough, and Respiratory Failure

Carly Fabrizio, DO : An Unusual Case of Submassive Hemoptysis

Meilinh Thi, DO : A Case to Make Your Skin Crawl

Garrett Harp, MD : Lambertosis: A Lung Cancer Mimic

Malik Khan, MD : Pleural Epithelioid Hemangioendothelioma: A Case Report

Priya Patel, MD : A Troubling Trifecta: Pulmonary Alveolar Proteinosis and Pneumocystis Pneumonia in Acute Myeloid Leukemia

Atul Palkar, MD : SGLT2 Inhibitors: Mind the Gap

Ji Yeon Lee, MD : Making Unusual Connections: Fibrosing Mediastinitis Leading to Bronchoesophageal Fistula

Sailm Daouk, MD : A Rare Form of Invasive Aspergillus Infection in a Severely Immunocompromised Host

Venkata Ravi Kumar Angirekula, MD : Vanishing Lung

Stephen Milan, MD : An Unexpected Mass

Lelia Logue, MD : A Rare Cause of Dysphagia

Daniel Hershberger, MD : Rapidly Progressive Hypoxic Respiratory Failure After a Rash: A Case of Clinically Amyopathic Dermatomyositis (CADM)-Associated ILD

 

 

Fellow Case Report Poster Winners

Krishna Siva Sai Kakkera

An Unusual Case of Crypotococcal Pleural Effusion

George Cheng

Use of Laparoscopic Suction Irrigator With Rigid Pleuroscope in Medical Thoracoscopy

Matt Koroscil

Wong Type Dermatomyositis Complicated by Interstitial Lung Disease

Derek Hansen

Acute Fibrinous and Organizing Pneumonia Following Hematopoietic Stem Cell Transplantation Responsive to Corticosteroid Therapy

Ala Eddin Sagar

Pulmonary Embolism Caused by Thrombin-Based Hemostatic Matrix After Discectomy

Sandeep Chennadi

Systemic Lupus Erythematosus (SLE) With Refractory Bilateral Chylothorax and Chylous Ascites

Medical Student/Resident Case Report Poster Winners

Justin Fiala

Pulmonary Presentation Without Concurrent Bone Involvement in Erdheim-Chester Disease: A Report of Two Cases

Navitha Ramesh

A Fatal Migration: A Case of Intra-Cardiac Embolization of a Peripheral Stent

Humna Abid Memon

Use of Extracorporeal Membrane Oxygenation in Postpartum Management of a Patient With PAH

Vanessa Ohleyer

A Case of Unusual Anatomy for an Uncommon Mediastinal Tumor

Tanushree Gahlot

Three Unusual Presentations of Job’s Syndrome (Hyper Immunoglobulin E Syndrome)

NetWorks Challenge Winners

Round 1

Women’s Lung Health NetWork

Round 2

Practice and Operations NetWork-1st place

Home-Based Mechanical Ventilation and Neuromuscular Disease NetWorks – 2nd place

Round 3

Home-Based Mechanical Ventilation, Neuromuscular Disease, and the Women’s Lung Health NetWorks

CHEST Bingo Winners

Youseff Anid, MD, FCCP

Karen Cochran, ACNP

Molly Howsware, DO

Katie Jeans, MD

Genovena Medina, RN

Gregory Eisinger, MD

Saurabh Mittal, MD, MBBS

Navitha Ramesh, MD

Dalvinder Dhillon, MD

Teresita Saylor, MD, FCCP

Carl Kaplan, MD, FCCP

Vishal Patel, MBBS, FCCP

Erin Peterson, CNP

Lilian Pereira, DO

 

We all know that, with the great success of CHEST 2016, everyone who shared that event is a winner. But, we would especially like to call out some of the special winners who were recognized during our annual meeting.

CHEST Awards

College Medalist Award

Lewis J. Rubin, MD, FCCP

Distinguished Service Award

Kim D. French, MHSA, CAPPM, FCCP

Alfred Soffer Award for Editorial Excellence

Seth J. Koenig, MD, FCCP

Master Clinician Educator Award

Jack D. Buckley, MD, MPH, FCCP

Distinguished Scientist Honor Lecture

Jay Nadel, MD

Edward C. Rosenow III, MD, Master FCCP/Master Teacher Honor Lecture

Suhail Raoof, MBBS, FCCP

Murray Kornfeld Memorial Founders Lecture

Michael Niederman, MD, FCCP Pasquale Ciaglia Memorial Lecture Kevin L. Kovitz, MD, FCCP

Roger C. Bone Memorial Lecture

Robert A. Berg, MD Thomas L. Petty, MD, Master FCCP Memorial Lecture Nicola A. Hanania, MD, MS, FCCP Margaret Pfrommer Memorial Lecture in Long-term Mechanical Ventilation Thomas G. Keens, MD Om P. Sharma, MD, Master FCCP Memorial Lecture Robert P. Baughman, MD, FCCP

Early Career Educator

Gabriel Bosslet, MD, FCCP

CHEST Challenge Championship 2016

1st Place

The University of Arizona

Huthayfa Ateeli, MBBS Naser Mahmoud, MD

Muna Omar, MD, MBBS


PD: James L. Knepler Jr.

2nd Place

New York Methodist Hospital

Anu R. Jacob, MD

Stephen D. Milan, MD

Jordan Taillon, MD


PD: Anthony G. Saleh, MD, FCCP

3rd Place

Interfaith Medical Center

Chidozie C. Agu, MD

Saroj P. Kandel, MBBS
Divya Salhan, MD, MBBS

PD: Marie Frances J. Schmidt, MD, FCCP

CHEST Foundation Grant Winners

GlaxoSmithKline Distinguished Scholar in Respiratory Health

Don Hayes Jr., MD, FCCP The Research Institute at Nationwide Children’s Hospital

Implications of the Lung Allocation Score in Prioritizing Critically Ill Patients for Lung Transplantation

Supported by GlaxoSmithKline.

2016 Research Grantees

Alice Turner, MBChB, MRCP, PhD

University of Birmingham, United Kingdom

CHEST Foundation and the Alpha-1 Foundation Research Grant in Alpha-1 Antitrypsin Deficiency

Improving Access to Augmentation: A Propensity-Matching Study Between the UK AATD Registry and AlphaNet

This grant is jointly supported by the CHEST Foundation and the Alpha-1 Foundation.

Robert Busch, MD

Brigham and Women’s Hospital, Channing Division of Network Medicine

CHEST Foundation Research Grant in Chronic Obstructive Pulmonary Disease

Methylation Quantitative Trait Loci: Markers of Race-Specific Disparities in African Americans With COPD

This grant is supported by AstraZeneca.

Clemens Grassberger, PhD

Massachusetts General Hospital – Harvard University

CHEST Foundation Research Grant in Lung Cancer

Dynamic FLT-PET as Biomarker for Early Response in Locally Advanced Lung Cancer Patients

This grant is supported by Genentech Inc.

 

 

Cristina Russo, MD, PhD

Bambino Gesù Children’s Hospital, Rome, Italy

CHEST Foundation Research Grant in Nontuberculous Mycobacteria

A Proteomic-Metaproteomic Analysis Approach Allows Identification of Drug Target Candidates for the Future Design of Preventive, Diagnostic, and Therapeutic Strategies Against Nontuberculous Mycobacteria Diseases

This grant is supported by Insmed.

Peter Leary, MD, MS

University of Washington

CHEST Foundation Research Grant in Pulmonary Arterial Hypertension

Expression Profiling in Pulmonary Arterial Hypertension

This grant is supported by Actelion Pharmaceuticals, US, Inc.

Brett Ley, MD

University of California, San Francisco

CHEST Foundation Research Grant in Pulmonary Fibrosis

Extracellular Circulation RNAs as Predictors of Disease Progression in Idiopathic Pulmonary Fibrosis

This grant is supported by Boehringer Ingelheim Pharmaceuticals & Genentech Inc.

Sydney Montesi, MD

Massachusetts General Hospital

CHEST Foundation Research Grant in Pulmonary Fibrosis

Gadofosveset-Enhanced Lung MRI to Detect Idiopathic Pulmonary Fibrosis Disease Activity

This grant is supported by Boehringer Ingelheim Pharmaceuticals & Genentech Inc.

Farbod Rahaghi, MD, PhD

Brigham and Women’s Hospital

CHEST Foundation Research Grant in Venous Thromboembolism

CT Scan-Based Markers for Prediction of Outcomes in Acute Pulmonary Embolism

This grant is supported by Daiichi Sankyo.

Catherine Oberg, MD

Icahn School of Medicine at Mount Sinai

CHEST Foundation Research Grant in Women’s Lung Health

Effects of Household Air Pollution on Airway Inflammation, Lung Function, and Respiratory Symptoms

This grant is supported in full by the CHEST Foundation.

2016 Community Service Grantee

Ethel Jane Carter, MD, FCCP

Warren Alpert School of Medicine at Brown University

CHEST Foundation Community Service Grant Honoring D. Robert McCaffree, MD, Master FCCP

East African Training Initiative ( EATI) in Pulmonary Medicine

2016 NetWorks Challenge Travel Grantees

Debarsee Banerjee, MS, MD

Women’s Health NetWork

Drew Harris, MD

Occupational and Environmental Health NetWork

Kerry Hena, MD

Occupational and Environmental Health NetWork

Amanpreet Kaur, MD

Women’s Health NetWork

2016 Diversity Travel Grant Winners

John B. Bishara, DO

Renato F. Blanco Jr., MD

Angel Coz-Yataco, MD
Sherie A. Gause, MD

Anthony Nebor, MD

James T. Williams, MD



Alfred Soffer Research Award Winners

Kerry Hena, MD

Deepak Pradhan, MD, FCCP

Young Investigator Award Winners

Elizabeth Becker: Clinical Characteristics of Sarcoidosis in World Trade Center (WTC) Exposed Fire Department of the City of New York (FDNY) Firefighters

Daniel Altman, MD : Cost-Effectiveness of Universally Funding Smoking Cessation Pharmacotherapy

Top 3 Poster Winners

Epaminondas Kosmas, MD, PhD, FCCP : Bronchiectasis in Patients With COPD: An Irrelevant Imaging Finding or a Clinically Important Phenotype?

Mark Regala, MD, BS : Evaluation of Outcomes of Post-Extubation Dysphagia in Elderly Patients

Massa Zantah, MD : Correlation of Esophageal Dilatation and Pulmonary Fibrosis in Scleroderma

Runner-up: Alev Gurgun, MD : Pulmonary Rehabilitation Response in Elderly and Younger Patients With COPD

Case Report Slide Winners

John Egan, MD, BA : An Unusual Cause of Tracheal Stenosis Due to a Vascular Anomaly Successfully Managed With Silicone Airway Stenting Prior to Definitive Vascular Repair

Harprett Grewal, MD : Bladder PTLD: First Reported Case of Post-Transplant Lymphoproliferative Disorder (PTLD) in the Bladder in a Lung Transplant Recipient

Michael Fingerhood, MD, MPH : Pulmonary Overlap Histiocytosis: A Rare Case of Interstitial Lung Disease Due to Erdheim Chester Disease in a Patient With Langerhans Cell Histiocytosis and Myelodisplastic Syndrome

Yihenew Negatu, MD : Acute ST Elevation Myocardial Infarction Related to Carbon Monoxide Poisoning in a Young Patient Without Coronary Artery Disease

Stephanie Wappel, MD : False-Negative Pet Imaging in Early Stage Malignant Pleural Mesothelioma

Lina Miyakawa, MD : Restrictive EGFR Mutation

Jeffrey Bonenfant, DO : A Unique Case of Follicular Bronchiolitis

Melissa Myers, MD : Seeing the Forest and Not Just the Trees: A Case of Recurrent Fever, Cough, and Respiratory Failure

Carly Fabrizio, DO : An Unusual Case of Submassive Hemoptysis

Meilinh Thi, DO : A Case to Make Your Skin Crawl

Garrett Harp, MD : Lambertosis: A Lung Cancer Mimic

Malik Khan, MD : Pleural Epithelioid Hemangioendothelioma: A Case Report

Priya Patel, MD : A Troubling Trifecta: Pulmonary Alveolar Proteinosis and Pneumocystis Pneumonia in Acute Myeloid Leukemia

Atul Palkar, MD : SGLT2 Inhibitors: Mind the Gap

Ji Yeon Lee, MD : Making Unusual Connections: Fibrosing Mediastinitis Leading to Bronchoesophageal Fistula

Sailm Daouk, MD : A Rare Form of Invasive Aspergillus Infection in a Severely Immunocompromised Host

Venkata Ravi Kumar Angirekula, MD : Vanishing Lung

Stephen Milan, MD : An Unexpected Mass

Lelia Logue, MD : A Rare Cause of Dysphagia

Daniel Hershberger, MD : Rapidly Progressive Hypoxic Respiratory Failure After a Rash: A Case of Clinically Amyopathic Dermatomyositis (CADM)-Associated ILD

 

 

Fellow Case Report Poster Winners

Krishna Siva Sai Kakkera

An Unusual Case of Crypotococcal Pleural Effusion

George Cheng

Use of Laparoscopic Suction Irrigator With Rigid Pleuroscope in Medical Thoracoscopy

Matt Koroscil

Wong Type Dermatomyositis Complicated by Interstitial Lung Disease

Derek Hansen

Acute Fibrinous and Organizing Pneumonia Following Hematopoietic Stem Cell Transplantation Responsive to Corticosteroid Therapy

Ala Eddin Sagar

Pulmonary Embolism Caused by Thrombin-Based Hemostatic Matrix After Discectomy

Sandeep Chennadi

Systemic Lupus Erythematosus (SLE) With Refractory Bilateral Chylothorax and Chylous Ascites

Medical Student/Resident Case Report Poster Winners

Justin Fiala

Pulmonary Presentation Without Concurrent Bone Involvement in Erdheim-Chester Disease: A Report of Two Cases

Navitha Ramesh

A Fatal Migration: A Case of Intra-Cardiac Embolization of a Peripheral Stent

Humna Abid Memon

Use of Extracorporeal Membrane Oxygenation in Postpartum Management of a Patient With PAH

Vanessa Ohleyer

A Case of Unusual Anatomy for an Uncommon Mediastinal Tumor

Tanushree Gahlot

Three Unusual Presentations of Job’s Syndrome (Hyper Immunoglobulin E Syndrome)

NetWorks Challenge Winners

Round 1

Women’s Lung Health NetWork

Round 2

Practice and Operations NetWork-1st place

Home-Based Mechanical Ventilation and Neuromuscular Disease NetWorks – 2nd place

Round 3

Home-Based Mechanical Ventilation, Neuromuscular Disease, and the Women’s Lung Health NetWorks

CHEST Bingo Winners

Youseff Anid, MD, FCCP

Karen Cochran, ACNP

Molly Howsware, DO

Katie Jeans, MD

Genovena Medina, RN

Gregory Eisinger, MD

Saurabh Mittal, MD, MBBS

Navitha Ramesh, MD

Dalvinder Dhillon, MD

Teresita Saylor, MD, FCCP

Carl Kaplan, MD, FCCP

Vishal Patel, MBBS, FCCP

Erin Peterson, CNP

Lilian Pereira, DO

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Joint CHEST-SGP Congress 2017

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Join leaders in CHEST medicine for a program designed by clinicians for clinicians.

 

Basel, Switzerland June 7-9

Join leaders in CHEST medicine for a program designed by clinicians for clinicians.

The Joint Congress organized by CHEST and the Swiss Society of Pneumology will be held from June 7-9 in Basel, Switzerland. The program has been designed by more than 140 faculty members from both the United States and Europe, and it aims to provide a robust overview of all aspects of respiratory medicine through interactive sessions, plenary discussions, critical appraisals on controversial topics, and a review of the last year of published works.

The Joint Congress also provides the opportunity to take part in hands-on simulation in areas such as lung function techniques including body plethysmography, N2 washout techniques, and respiratory physiotherapy. Another hands-on opportunity is the interventional pneumology CHEST experience course, which will be held from 8:00 AM-11:00 AM on June 7 and 8 on site. This course will provide an overview of conventional and EBUS-guided TBNA, an anatomy identification of airway nodes, management of airway bleeding, and management of pneumothorax. This course is ideal for clinicians and health-care professionals with specialties in pulmonary, critical care, and intensive care medicine, as well as thoracic surgery.

The program at the Joint CHEST-SGP Congress aims to improve the patient care abilities of every attendee, as well as provide an ideal environment for networking with leaders in your field.

The call for abstracts remains open until January 24, 2017. The abstract topic areas are:

  • Airway disease
  • Interstitial lung disease
  • Sleep/Breathing
  • Lung cancer
  • Epidemiology/Rehabilitation
  • Interventional pneumology
  • Pulmonary hypertension
  • Basic science
  • Thoracic surgery
  • Pediatrics

All abstracts must be submitted via the Joint Congress abstracts web portal www.chest-sgp-switzerland2017.org.

CHEST recognizes the value of international outreach, and this Joint Congress advances that initiative. CHEST aims to standardize the patient care across borders and to encourage international collaboration to build the future of chest medicine. To further this mission, an application has been made to the European Accreditation Council for Continuing Medical Education (EACCME®) for CME accreditation of this event. Additionally, an application has been made to the European Board for Accreditation in Pneumology (EBAP) to provide quality assurance and CME for the event.

For more information or to register, visit the CHEST Joint Congress website www.chest-sgp-switzerland2017.org. Early registration ends on March 16, 2017.

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Join leaders in CHEST medicine for a program designed by clinicians for clinicians.
Join leaders in CHEST medicine for a program designed by clinicians for clinicians.

 

Basel, Switzerland June 7-9

Join leaders in CHEST medicine for a program designed by clinicians for clinicians.

The Joint Congress organized by CHEST and the Swiss Society of Pneumology will be held from June 7-9 in Basel, Switzerland. The program has been designed by more than 140 faculty members from both the United States and Europe, and it aims to provide a robust overview of all aspects of respiratory medicine through interactive sessions, plenary discussions, critical appraisals on controversial topics, and a review of the last year of published works.

The Joint Congress also provides the opportunity to take part in hands-on simulation in areas such as lung function techniques including body plethysmography, N2 washout techniques, and respiratory physiotherapy. Another hands-on opportunity is the interventional pneumology CHEST experience course, which will be held from 8:00 AM-11:00 AM on June 7 and 8 on site. This course will provide an overview of conventional and EBUS-guided TBNA, an anatomy identification of airway nodes, management of airway bleeding, and management of pneumothorax. This course is ideal for clinicians and health-care professionals with specialties in pulmonary, critical care, and intensive care medicine, as well as thoracic surgery.

The program at the Joint CHEST-SGP Congress aims to improve the patient care abilities of every attendee, as well as provide an ideal environment for networking with leaders in your field.

The call for abstracts remains open until January 24, 2017. The abstract topic areas are:

  • Airway disease
  • Interstitial lung disease
  • Sleep/Breathing
  • Lung cancer
  • Epidemiology/Rehabilitation
  • Interventional pneumology
  • Pulmonary hypertension
  • Basic science
  • Thoracic surgery
  • Pediatrics

All abstracts must be submitted via the Joint Congress abstracts web portal www.chest-sgp-switzerland2017.org.

CHEST recognizes the value of international outreach, and this Joint Congress advances that initiative. CHEST aims to standardize the patient care across borders and to encourage international collaboration to build the future of chest medicine. To further this mission, an application has been made to the European Accreditation Council for Continuing Medical Education (EACCME®) for CME accreditation of this event. Additionally, an application has been made to the European Board for Accreditation in Pneumology (EBAP) to provide quality assurance and CME for the event.

For more information or to register, visit the CHEST Joint Congress website www.chest-sgp-switzerland2017.org. Early registration ends on March 16, 2017.

 

Basel, Switzerland June 7-9

Join leaders in CHEST medicine for a program designed by clinicians for clinicians.

The Joint Congress organized by CHEST and the Swiss Society of Pneumology will be held from June 7-9 in Basel, Switzerland. The program has been designed by more than 140 faculty members from both the United States and Europe, and it aims to provide a robust overview of all aspects of respiratory medicine through interactive sessions, plenary discussions, critical appraisals on controversial topics, and a review of the last year of published works.

The Joint Congress also provides the opportunity to take part in hands-on simulation in areas such as lung function techniques including body plethysmography, N2 washout techniques, and respiratory physiotherapy. Another hands-on opportunity is the interventional pneumology CHEST experience course, which will be held from 8:00 AM-11:00 AM on June 7 and 8 on site. This course will provide an overview of conventional and EBUS-guided TBNA, an anatomy identification of airway nodes, management of airway bleeding, and management of pneumothorax. This course is ideal for clinicians and health-care professionals with specialties in pulmonary, critical care, and intensive care medicine, as well as thoracic surgery.

The program at the Joint CHEST-SGP Congress aims to improve the patient care abilities of every attendee, as well as provide an ideal environment for networking with leaders in your field.

The call for abstracts remains open until January 24, 2017. The abstract topic areas are:

  • Airway disease
  • Interstitial lung disease
  • Sleep/Breathing
  • Lung cancer
  • Epidemiology/Rehabilitation
  • Interventional pneumology
  • Pulmonary hypertension
  • Basic science
  • Thoracic surgery
  • Pediatrics

All abstracts must be submitted via the Joint Congress abstracts web portal www.chest-sgp-switzerland2017.org.

CHEST recognizes the value of international outreach, and this Joint Congress advances that initiative. CHEST aims to standardize the patient care across borders and to encourage international collaboration to build the future of chest medicine. To further this mission, an application has been made to the European Accreditation Council for Continuing Medical Education (EACCME®) for CME accreditation of this event. Additionally, an application has been made to the European Board for Accreditation in Pneumology (EBAP) to provide quality assurance and CME for the event.

For more information or to register, visit the CHEST Joint Congress website www.chest-sgp-switzerland2017.org. Early registration ends on March 16, 2017.

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Adding epoetin alfa to lenalidomide boosted myelodysplastic syndrome responses

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– Dual therapy with lenalidomide and epoetin alfa was safe and led to freedom from transfusion significantly more often than lenalidomide alone in patients with erythropoietin-refractory, lower-risk, non-del(5q) myelodysplastic syndromes, according to a randomized phase III head-to-head trial.

After 16 weeks of treatment, 33% of patients who received both lenalidomide and epoetin alfa met International Working Group 2000 criteria for major erythroid response, compared with only 14% of patients receiving lenalidomide monotherapy (P = .03), Alan F. List, MD, reported at the annual meeting of the American Society of Hematology.

H. Lee Moffitt Cancer Center
Dr. Alan F. List
Combination therapy also worked longer – median duration of response was 25 months, versus 13 months for lenalidomide only, said Dr. List of H. Lee Moffitt Cancer Center and Research Institute in Tampa. These results illustrate the power of lenalidomide to restore sensitivity to epoetin alfa in patients with lower-risk, non-del(5q) myelodysplastic syndrome (MDS), he emphasized.

Recombinant human erythropoietin improves anemia in some cases of MDS, but salvage options are limited. “Cytokine therapy is generally ineffective in patients with high transfusion burden or elevated serum erythropoietin level,” Dr. List said.

Lenalidomide (Revlimid) promotes the in vitro expansion of primitive erythroid precursors, and in a recent phase III, placebo-controlled trial, the immunomodulator improved erythropoiesis in about 25% of lower-risk, non-del(5q) MDS patients who were azanucleoside-naïve and transfusion-dependent, with effects lasting about 8 months. In another pilot study, adding epoetin alfa to lenalidomide induced erythroid responses in 28% of MDS patients who were not responding to lenalidomide alone. “This suggests that lenalidomide overcomes resistance and augments response to recombinant human erythropoietin,” Dr. List explained.

For their phase III trial, he and his associates randomly assigned erythropoietin-refractory, lower-risk, non-del(5q) MDS patients with hemoglobin levels under 9.5 g/dL to receive lenalidomide (10 mg per day for 21 days every 28 days) with or without epoetin alfa (weekly dose, 60,000 units subcutaneously). A total of 14% of patients had previously received azanucleoside therapy, about 92% had received erythropoietic stimulating agents, and median serum erythropoietin levels were 167 and 143 mU per mL in the monotherapy and dual therapy arms, respectively.

In accordance with International Working Group 2000 criteria, the researchers defined major erythroid response as transfusion independence for least 8 consecutive weeks, with at least a 1 g/dL increase in hemoglobin levels if patients were transfusion-dependent at baseline, and at least a 2 g/dL rise in hemoglobin if they were transfusion-independent.

In an interim analysis of 163 patients, 26% of the dual therapy group and 11% of lenalidomide-only patients met this primary endpoint (P = .02). These results met predefined criteria for stopping the study, after which 34 lenalidomide nonresponders crossed over to dual therapy. In all, 21% of these patients also had a major erythroid response, Dr. List said.

A multivariable analysis that included disease duration, International Prognostic Scoring System low versus intermediate-1 risk status, baseline erythropoietin level, and prior azanucleoside exposure showed that only dual lenalidomide–epoetin alfa therapy predicted major erythroid response. Specifically, dual therapy increased the odds of this outcome by about 63% when compared with lenalidomide monotherapy (P = .03).

Secondary analyses linked major erythroid response to having more low than high molecular weight CD45 isoform. In fact, the median ratio of high to low molecular weight CD45 was 1.5 among responders and 4.2 among nonresponders (P = .04) This finding fits the hypothesis that larger CD45 isoforms keep lenalidomide from enhancing erythropoietin receptor signaling, Dr. List said. Indeed, rates of major erythroid response to lenalidomide–epoetin alfa therapy were 73% when patients had a low isoform ratio, but were only 18% when they had a high isoform ratio (P = .03). The CD45 isoform ratio distinguished responders from nonresponders with a sensitivity and specificity of 80% and 75%, respectively, Dr. List said.

Grade 3 or higher nonhematologic events affected about a quarter of patients in each arm, and rates of individual events were similar. The most common serious adverse event was fatigue (5% of patients), followed by elevated serum creatinine (3.7%). About 10% of patients in each arm died while on study.

The National Institutes of Health supported the study. Dr. List had no relevant financial disclosures.
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– Dual therapy with lenalidomide and epoetin alfa was safe and led to freedom from transfusion significantly more often than lenalidomide alone in patients with erythropoietin-refractory, lower-risk, non-del(5q) myelodysplastic syndromes, according to a randomized phase III head-to-head trial.

After 16 weeks of treatment, 33% of patients who received both lenalidomide and epoetin alfa met International Working Group 2000 criteria for major erythroid response, compared with only 14% of patients receiving lenalidomide monotherapy (P = .03), Alan F. List, MD, reported at the annual meeting of the American Society of Hematology.

H. Lee Moffitt Cancer Center
Dr. Alan F. List
Combination therapy also worked longer – median duration of response was 25 months, versus 13 months for lenalidomide only, said Dr. List of H. Lee Moffitt Cancer Center and Research Institute in Tampa. These results illustrate the power of lenalidomide to restore sensitivity to epoetin alfa in patients with lower-risk, non-del(5q) myelodysplastic syndrome (MDS), he emphasized.

Recombinant human erythropoietin improves anemia in some cases of MDS, but salvage options are limited. “Cytokine therapy is generally ineffective in patients with high transfusion burden or elevated serum erythropoietin level,” Dr. List said.

Lenalidomide (Revlimid) promotes the in vitro expansion of primitive erythroid precursors, and in a recent phase III, placebo-controlled trial, the immunomodulator improved erythropoiesis in about 25% of lower-risk, non-del(5q) MDS patients who were azanucleoside-naïve and transfusion-dependent, with effects lasting about 8 months. In another pilot study, adding epoetin alfa to lenalidomide induced erythroid responses in 28% of MDS patients who were not responding to lenalidomide alone. “This suggests that lenalidomide overcomes resistance and augments response to recombinant human erythropoietin,” Dr. List explained.

For their phase III trial, he and his associates randomly assigned erythropoietin-refractory, lower-risk, non-del(5q) MDS patients with hemoglobin levels under 9.5 g/dL to receive lenalidomide (10 mg per day for 21 days every 28 days) with or without epoetin alfa (weekly dose, 60,000 units subcutaneously). A total of 14% of patients had previously received azanucleoside therapy, about 92% had received erythropoietic stimulating agents, and median serum erythropoietin levels were 167 and 143 mU per mL in the monotherapy and dual therapy arms, respectively.

In accordance with International Working Group 2000 criteria, the researchers defined major erythroid response as transfusion independence for least 8 consecutive weeks, with at least a 1 g/dL increase in hemoglobin levels if patients were transfusion-dependent at baseline, and at least a 2 g/dL rise in hemoglobin if they were transfusion-independent.

In an interim analysis of 163 patients, 26% of the dual therapy group and 11% of lenalidomide-only patients met this primary endpoint (P = .02). These results met predefined criteria for stopping the study, after which 34 lenalidomide nonresponders crossed over to dual therapy. In all, 21% of these patients also had a major erythroid response, Dr. List said.

A multivariable analysis that included disease duration, International Prognostic Scoring System low versus intermediate-1 risk status, baseline erythropoietin level, and prior azanucleoside exposure showed that only dual lenalidomide–epoetin alfa therapy predicted major erythroid response. Specifically, dual therapy increased the odds of this outcome by about 63% when compared with lenalidomide monotherapy (P = .03).

Secondary analyses linked major erythroid response to having more low than high molecular weight CD45 isoform. In fact, the median ratio of high to low molecular weight CD45 was 1.5 among responders and 4.2 among nonresponders (P = .04) This finding fits the hypothesis that larger CD45 isoforms keep lenalidomide from enhancing erythropoietin receptor signaling, Dr. List said. Indeed, rates of major erythroid response to lenalidomide–epoetin alfa therapy were 73% when patients had a low isoform ratio, but were only 18% when they had a high isoform ratio (P = .03). The CD45 isoform ratio distinguished responders from nonresponders with a sensitivity and specificity of 80% and 75%, respectively, Dr. List said.

Grade 3 or higher nonhematologic events affected about a quarter of patients in each arm, and rates of individual events were similar. The most common serious adverse event was fatigue (5% of patients), followed by elevated serum creatinine (3.7%). About 10% of patients in each arm died while on study.

The National Institutes of Health supported the study. Dr. List had no relevant financial disclosures.

 

– Dual therapy with lenalidomide and epoetin alfa was safe and led to freedom from transfusion significantly more often than lenalidomide alone in patients with erythropoietin-refractory, lower-risk, non-del(5q) myelodysplastic syndromes, according to a randomized phase III head-to-head trial.

After 16 weeks of treatment, 33% of patients who received both lenalidomide and epoetin alfa met International Working Group 2000 criteria for major erythroid response, compared with only 14% of patients receiving lenalidomide monotherapy (P = .03), Alan F. List, MD, reported at the annual meeting of the American Society of Hematology.

H. Lee Moffitt Cancer Center
Dr. Alan F. List
Combination therapy also worked longer – median duration of response was 25 months, versus 13 months for lenalidomide only, said Dr. List of H. Lee Moffitt Cancer Center and Research Institute in Tampa. These results illustrate the power of lenalidomide to restore sensitivity to epoetin alfa in patients with lower-risk, non-del(5q) myelodysplastic syndrome (MDS), he emphasized.

Recombinant human erythropoietin improves anemia in some cases of MDS, but salvage options are limited. “Cytokine therapy is generally ineffective in patients with high transfusion burden or elevated serum erythropoietin level,” Dr. List said.

Lenalidomide (Revlimid) promotes the in vitro expansion of primitive erythroid precursors, and in a recent phase III, placebo-controlled trial, the immunomodulator improved erythropoiesis in about 25% of lower-risk, non-del(5q) MDS patients who were azanucleoside-naïve and transfusion-dependent, with effects lasting about 8 months. In another pilot study, adding epoetin alfa to lenalidomide induced erythroid responses in 28% of MDS patients who were not responding to lenalidomide alone. “This suggests that lenalidomide overcomes resistance and augments response to recombinant human erythropoietin,” Dr. List explained.

For their phase III trial, he and his associates randomly assigned erythropoietin-refractory, lower-risk, non-del(5q) MDS patients with hemoglobin levels under 9.5 g/dL to receive lenalidomide (10 mg per day for 21 days every 28 days) with or without epoetin alfa (weekly dose, 60,000 units subcutaneously). A total of 14% of patients had previously received azanucleoside therapy, about 92% had received erythropoietic stimulating agents, and median serum erythropoietin levels were 167 and 143 mU per mL in the monotherapy and dual therapy arms, respectively.

In accordance with International Working Group 2000 criteria, the researchers defined major erythroid response as transfusion independence for least 8 consecutive weeks, with at least a 1 g/dL increase in hemoglobin levels if patients were transfusion-dependent at baseline, and at least a 2 g/dL rise in hemoglobin if they were transfusion-independent.

In an interim analysis of 163 patients, 26% of the dual therapy group and 11% of lenalidomide-only patients met this primary endpoint (P = .02). These results met predefined criteria for stopping the study, after which 34 lenalidomide nonresponders crossed over to dual therapy. In all, 21% of these patients also had a major erythroid response, Dr. List said.

A multivariable analysis that included disease duration, International Prognostic Scoring System low versus intermediate-1 risk status, baseline erythropoietin level, and prior azanucleoside exposure showed that only dual lenalidomide–epoetin alfa therapy predicted major erythroid response. Specifically, dual therapy increased the odds of this outcome by about 63% when compared with lenalidomide monotherapy (P = .03).

Secondary analyses linked major erythroid response to having more low than high molecular weight CD45 isoform. In fact, the median ratio of high to low molecular weight CD45 was 1.5 among responders and 4.2 among nonresponders (P = .04) This finding fits the hypothesis that larger CD45 isoforms keep lenalidomide from enhancing erythropoietin receptor signaling, Dr. List said. Indeed, rates of major erythroid response to lenalidomide–epoetin alfa therapy were 73% when patients had a low isoform ratio, but were only 18% when they had a high isoform ratio (P = .03). The CD45 isoform ratio distinguished responders from nonresponders with a sensitivity and specificity of 80% and 75%, respectively, Dr. List said.

Grade 3 or higher nonhematologic events affected about a quarter of patients in each arm, and rates of individual events were similar. The most common serious adverse event was fatigue (5% of patients), followed by elevated serum creatinine (3.7%). About 10% of patients in each arm died while on study.

The National Institutes of Health supported the study. Dr. List had no relevant financial disclosures.
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Key clinical point: Dual therapy with lenalidomide and epoetin alfa was more effective than lenalidomide monotherapy in patients with erythropoietin-refractory, lower-risk, non-del(5q) myelodysplastic syndrome.

Major finding: After 16 weeks of treatment, 33% of patients who received both agents met International Working Group 2000 criteria for major erythroid response, compared with 14% of patients receiving lenalidomide monotherapy (P = .03).

Data source: An interim analysis of 163 patients in the phase III ECOG-ACRIN E2905 Intergroup Study.

Disclosures: The National Institutes of Health supported the study. Dr. List had no relevant financial disclosures.

ACGME seeks to return trainees’ maximum shifts to 24 hours

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First-year residents may be permitted to work up to 24 consecutive hours – 8 hours longer than they can now – under a proposal from a task force of the Accreditation Council for Graduate Medical Education (ACGME).

 

 

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First-year residents may be permitted to work up to 24 consecutive hours – 8 hours longer than they can now – under a proposal from a task force of the Accreditation Council for Graduate Medical Education (ACGME).

 

 


First-year residents may be permitted to work up to 24 consecutive hours – 8 hours longer than they can now – under a proposal from a task force of the Accreditation Council for Graduate Medical Education (ACGME).

 

 

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