Supplements

Summit Director:
Amir K. Jaffer, MD

Contents

Summit Faculty

Summit Program

Abstract 1: Application of 2007 ACC/AHA guidelines on perioperative cardiovascular evaluation and care for noncardiac surgery using decision support tools
BobbieJean Sweitzer, Michael Vigoda, Vicente Behrens, Nikola Miljkovic, and Kris Arheart

Abstract 2: Prevalence of obstructive dleep spnea in patients presenting for hip or knee replacement surgery
Micah Beachy, DO; Jason Shiffermiller, MD; and Chad Vokoun, MD

Abstract 3: A protocol to triage preoperative assessments to either nurses or nurse practitioners/physician assistants
Anthony Basil, RN; Pamela Pennigar, FNP; David R. Wright, MD; and Ronald P. Olson, MD

Abstract 4: Application of 2007 ACC/AHA guidelines on perioperative cardiovascular evaluation and care for noncardiac surgery using decision support tools
BobbieJean Sweitzer, Michael Vigoda, Vicente Behrens, Nikola Miljkovic, and Kris Arheart

Abstract 5: Most anesthesiologists don’t correctly apply 2007 ACC/AHA guidelines on perioperative cardiac evaluation
BobbieJean Sweitzer, Michael Vigoda, Vicente Behrens, Nikola Miljkovic, Kris Arheart, and Richard Dutton

Abstract 6: Anesthesiology residents do not agree with their training programs on the degree to which the 2007 ACC/AHA guidelines are emphasized
BobbieJean Sweitzer, Michael Vigoda, Vicente Behrens, Nikola Miljkovic, and Kris Arheart

Abstract 7: Prevalence of obstructive sleep apnea in patients presenting for hip or knee replacement surgery
Micah Beachy, DO; Jason Shiffermiller, MD; and Chad Vokoun, MD

Abstract 8: A protocol to triage preoperative assessments to either nurses or nurse practitioners/physician assistants
Anthony Basil, RN; Pamela Pennigar, FNP; David R. Wright, MD; and Ronald P. Olson, MD

Abstract 9: Do ACEIs on the morning of surgery increase risk of intraoperative hypotension?
Steven L. Cohn, MD, and Kalia Skeete, MD

Abstract 10: One-year incidence of postoperative troponin revations in patients undergoing major orthopedic surgery
Michael Urban, MD, PhD; Stephen Wolfe, BS; Niel Sanghevi, BS; and Steven Magid, MD

Abstract 11: A review of preoperative clinic cardiology referrals for adults undergoing intermediate- and low-risk surgery
Susan Calderwood, MD; Jennifer Lee Morse, MS; and Damon R. Michaels, CCRP

Abstract 12: Patterns of preoperative consultation by risk and surgical specialty in a large health care system
Stephan Thilen, MD, MS; Christopher Bryson, MD, MS; Robert Reid, MD, PhD; and Miriam Treggiari, MD, MPH, PhD

Abstract 13: One-year incidence for admission to a critical care unit after major orthopedic surgery
Michael Urban, MD, PhD; Steven Magid, MD; and Michele Mangini, DNP

Abstract 14: Determination of the causes of long patient wait times in a preoperative evaluation clinic
Jean Kwo, MD; Devon Price, BS; Mary Elizabeth Ellbeg, RN; and Retsef Levi, PhD

Abstract 15: Does perioperative statin treatment affect hospital and ICU length of stay rollowing cardiac surgery: A systematic review
Vineet Chopra, MD, FACP, FHM; David Wesorick, MD; and Kim A. Eagle, MD

Abstract 16: Assessment of patient satisfaction of nurse screening vs complete preoperative assessment
Ronald Olson, MD, and Kathy Bock, RN

Abstract 17: Traumatic subdural hematoma: An update on morbidity
Rachel Thompson, MD; Christina Ryan, MD; Nancy Temkin, PhD; Richard Ellenbogen, MD; and Joann G. Elmore, MD, MPH

Abstract 18: Lipid emulsion as a lifesaving treatment for local anesthetic systemic toxicity (LAST)
Deepti Sachdev and Guy Weinberg, MD

Abstract 19: Perioperative ACLS recommendations should be modified for the treatment of local anesthetic toxicity
Adam Haas, MD, and Alexia Beccue, MD

Abstract 20: Preoperative EMR containing smart-set reminders improve accuracy of documentation by nonanesthesia clinicians during preoperative assessments
Angela Edwards, MD; Jill Grant, PA; and Ruth Hyde, MD

Abstract 21: POET: Procedure outcomes evaluation tool
Ahmad AbuSalah, MSc, and Terrence Adam, MD, PhD

Abstract 22: Results of a multidisciplinary preoperative assessment process for high-risk orthopedic patients
Terrence Adam, MD, PhD; Connie Parenti, MD; Terence Gioe, MD; and Karen Ringsred, MD

Abstract 23: Practical algorithm for preoperative evaluation of patients with liver disease
Madalina A. Vlase, PA-C, and Deborah C. Richman, MBChB, FFA(SA)

Abstract 24: Evaluation and management of isolated elevated aPTT
Sheila Hassan, MSN, NP; Patricia Kidik, MSN, NP; Catherine McGowan, MSN, NP; and Angela M. Bader, MD

Abstract 25: A perioperative triage plan for obstructive sleep apnea patients
Christian Altman, MD; R. Michael Boyer, DO; and Peter G. Kallas, MD

Abstract 26: Quantitative evaluation of handoff checklists
Jay Joshi, MD, and David Mayer, MD

Abstract 27: To deflate or not to deflate: Lap-Band® management in subsequent surgeries
Arjun Reddy, MD, and Deborah C. Richman, MBChB, FFA(SA)

Abstract 28: Takotsubo cardiomyopathy and resultant cardiogenic shock after mitral valve repair
Adam Evans, MD, MBA; Daniel B. Sims, MD; Nir Uriel, MD; Ulrich P. Jorde, MD; and Craig R. Smith, MD

Abstract 29: Intravenous vitamin K: Rapid reversal of warfarin and lack of subsequent warfarin resistance
Feras Abdul Khalek, MD; Interdeep Dhaliwal, MD; and Twylla Tassava, MD

Abstract 30: Cervical spine surgery: When not to extubate postoperatively
Carlos Mateo Mijares, MD; Doris Debs, ARNP, MSN-BC; Nicole Martin, MD; and Ronald Lee Samson, MD

Abstract 31: Total occlusion of oral cavity by mandibular sarcoma for resection: To intubate nasally or proceed to an awake tracheostomy?
Carlos Mateo Mijares, MD, and Maria DeLapena, MD

Abstract 32: Perioperative fatal embolic stroke associated with iron deficiency anemia and thrombocytosis
Carlos Mateo Mijares, MD; Nicole Martin, MD; and Ricardo Martinez-Ruiz, MD

Abstract 33: Conservative approach saves the day anesthesia-wise and surgical-wise
Carlos Mateo Mijares, MD; Bradley Shore, MD; Edward Zalkind, CRNA; and Nicole Martin, MD

Abstract 34: Predictors of acute kidney injury in patients undergoing total knee replacement surgery
Vishal Sehgal, MD; Pardeep Bansal, MD; Praveen Reddy, MD; Vishal Sharma, MD; Samuel Lesko, MD; John H. Doherty, MD; Theodore Tomaszewski, MD; Jack Prior, MD; Roger Getts, MD; and Jeremiah Eagan, MD

Abstract 35: Perioperative medical management of the Marfan patient undergoing repeat cardiothoracic surgery
Aashish Shah, MD, and Adam Skrzynski, MD

Index of abstract authors

Summit Director:
Amir K. Jaffer, MD

Contents

Summit Faculty

Summit Program

Abstract 1: Application of 2007 ACC/AHA guidelines on perioperative cardiovascular evaluation and care for noncardiac surgery using decision support tools
BobbieJean Sweitzer, Michael Vigoda, Vicente Behrens, Nikola Miljkovic, and Kris Arheart

Abstract 2: Prevalence of obstructive dleep spnea in patients presenting for hip or knee replacement surgery
Micah Beachy, DO; Jason Shiffermiller, MD; and Chad Vokoun, MD

Abstract 3: A protocol to triage preoperative assessments to either nurses or nurse practitioners/physician assistants
Anthony Basil, RN; Pamela Pennigar, FNP; David R. Wright, MD; and Ronald P. Olson, MD

Abstract 4: Application of 2007 ACC/AHA guidelines on perioperative cardiovascular evaluation and care for noncardiac surgery using decision support tools
BobbieJean Sweitzer, Michael Vigoda, Vicente Behrens, Nikola Miljkovic, and Kris Arheart

Abstract 5: Most anesthesiologists don’t correctly apply 2007 ACC/AHA guidelines on perioperative cardiac evaluation
BobbieJean Sweitzer, Michael Vigoda, Vicente Behrens, Nikola Miljkovic, Kris Arheart, and Richard Dutton

Abstract 6: Anesthesiology residents do not agree with their training programs on the degree to which the 2007 ACC/AHA guidelines are emphasized
BobbieJean Sweitzer, Michael Vigoda, Vicente Behrens, Nikola Miljkovic, and Kris Arheart

Abstract 7: Prevalence of obstructive sleep apnea in patients presenting for hip or knee replacement surgery
Micah Beachy, DO; Jason Shiffermiller, MD; and Chad Vokoun, MD

Abstract 8: A protocol to triage preoperative assessments to either nurses or nurse practitioners/physician assistants
Anthony Basil, RN; Pamela Pennigar, FNP; David R. Wright, MD; and Ronald P. Olson, MD

Abstract 9: Do ACEIs on the morning of surgery increase risk of intraoperative hypotension?
Steven L. Cohn, MD, and Kalia Skeete, MD

Abstract 10: One-year incidence of postoperative troponin revations in patients undergoing major orthopedic surgery
Michael Urban, MD, PhD; Stephen Wolfe, BS; Niel Sanghevi, BS; and Steven Magid, MD

Abstract 11: A review of preoperative clinic cardiology referrals for adults undergoing intermediate- and low-risk surgery
Susan Calderwood, MD; Jennifer Lee Morse, MS; and Damon R. Michaels, CCRP

Abstract 12: Patterns of preoperative consultation by risk and surgical specialty in a large health care system
Stephan Thilen, MD, MS; Christopher Bryson, MD, MS; Robert Reid, MD, PhD; and Miriam Treggiari, MD, MPH, PhD

Abstract 13: One-year incidence for admission to a critical care unit after major orthopedic surgery
Michael Urban, MD, PhD; Steven Magid, MD; and Michele Mangini, DNP

Abstract 14: Determination of the causes of long patient wait times in a preoperative evaluation clinic
Jean Kwo, MD; Devon Price, BS; Mary Elizabeth Ellbeg, RN; and Retsef Levi, PhD

Abstract 15: Does perioperative statin treatment affect hospital and ICU length of stay rollowing cardiac surgery: A systematic review
Vineet Chopra, MD, FACP, FHM; David Wesorick, MD; and Kim A. Eagle, MD

Abstract 16: Assessment of patient satisfaction of nurse screening vs complete preoperative assessment
Ronald Olson, MD, and Kathy Bock, RN

Abstract 17: Traumatic subdural hematoma: An update on morbidity
Rachel Thompson, MD; Christina Ryan, MD; Nancy Temkin, PhD; Richard Ellenbogen, MD; and Joann G. Elmore, MD, MPH

Abstract 18: Lipid emulsion as a lifesaving treatment for local anesthetic systemic toxicity (LAST)
Deepti Sachdev and Guy Weinberg, MD

Abstract 19: Perioperative ACLS recommendations should be modified for the treatment of local anesthetic toxicity
Adam Haas, MD, and Alexia Beccue, MD

Abstract 20: Preoperative EMR containing smart-set reminders improve accuracy of documentation by nonanesthesia clinicians during preoperative assessments
Angela Edwards, MD; Jill Grant, PA; and Ruth Hyde, MD

Abstract 21: POET: Procedure outcomes evaluation tool
Ahmad AbuSalah, MSc, and Terrence Adam, MD, PhD

Abstract 22: Results of a multidisciplinary preoperative assessment process for high-risk orthopedic patients
Terrence Adam, MD, PhD; Connie Parenti, MD; Terence Gioe, MD; and Karen Ringsred, MD

Abstract 23: Practical algorithm for preoperative evaluation of patients with liver disease
Madalina A. Vlase, PA-C, and Deborah C. Richman, MBChB, FFA(SA)

Abstract 24: Evaluation and management of isolated elevated aPTT
Sheila Hassan, MSN, NP; Patricia Kidik, MSN, NP; Catherine McGowan, MSN, NP; and Angela M. Bader, MD

Abstract 25: A perioperative triage plan for obstructive sleep apnea patients
Christian Altman, MD; R. Michael Boyer, DO; and Peter G. Kallas, MD

Abstract 26: Quantitative evaluation of handoff checklists
Jay Joshi, MD, and David Mayer, MD

Abstract 27: To deflate or not to deflate: Lap-Band® management in subsequent surgeries
Arjun Reddy, MD, and Deborah C. Richman, MBChB, FFA(SA)

Abstract 28: Takotsubo cardiomyopathy and resultant cardiogenic shock after mitral valve repair
Adam Evans, MD, MBA; Daniel B. Sims, MD; Nir Uriel, MD; Ulrich P. Jorde, MD; and Craig R. Smith, MD

Abstract 29: Intravenous vitamin K: Rapid reversal of warfarin and lack of subsequent warfarin resistance
Feras Abdul Khalek, MD; Interdeep Dhaliwal, MD; and Twylla Tassava, MD

Abstract 30: Cervical spine surgery: When not to extubate postoperatively
Carlos Mateo Mijares, MD; Doris Debs, ARNP, MSN-BC; Nicole Martin, MD; and Ronald Lee Samson, MD

Abstract 31: Total occlusion of oral cavity by mandibular sarcoma for resection: To intubate nasally or proceed to an awake tracheostomy?
Carlos Mateo Mijares, MD, and Maria DeLapena, MD

Abstract 32: Perioperative fatal embolic stroke associated with iron deficiency anemia and thrombocytosis
Carlos Mateo Mijares, MD; Nicole Martin, MD; and Ricardo Martinez-Ruiz, MD

Abstract 33: Conservative approach saves the day anesthesia-wise and surgical-wise
Carlos Mateo Mijares, MD; Bradley Shore, MD; Edward Zalkind, CRNA; and Nicole Martin, MD

Abstract 34: Predictors of acute kidney injury in patients undergoing total knee replacement surgery
Vishal Sehgal, MD; Pardeep Bansal, MD; Praveen Reddy, MD; Vishal Sharma, MD; Samuel Lesko, MD; John H. Doherty, MD; Theodore Tomaszewski, MD; Jack Prior, MD; Roger Getts, MD; and Jeremiah Eagan, MD

Abstract 35: Perioperative medical management of the Marfan patient undergoing repeat cardiothoracic surgery
Aashish Shah, MD, and Adam Skrzynski, MD

Index of abstract authors

Summit Director:
Amir K. Jaffer, MD

Contents

Summit Faculty

Summit Program

Abstract 1: Application of 2007 ACC/AHA guidelines on perioperative cardiovascular evaluation and care for noncardiac surgery using decision support tools
BobbieJean Sweitzer, Michael Vigoda, Vicente Behrens, Nikola Miljkovic, and Kris Arheart

Abstract 2: Prevalence of obstructive dleep spnea in patients presenting for hip or knee replacement surgery
Micah Beachy, DO; Jason Shiffermiller, MD; and Chad Vokoun, MD

Abstract 3: A protocol to triage preoperative assessments to either nurses or nurse practitioners/physician assistants
Anthony Basil, RN; Pamela Pennigar, FNP; David R. Wright, MD; and Ronald P. Olson, MD

Abstract 4: Application of 2007 ACC/AHA guidelines on perioperative cardiovascular evaluation and care for noncardiac surgery using decision support tools
BobbieJean Sweitzer, Michael Vigoda, Vicente Behrens, Nikola Miljkovic, and Kris Arheart

Abstract 5: Most anesthesiologists don’t correctly apply 2007 ACC/AHA guidelines on perioperative cardiac evaluation
BobbieJean Sweitzer, Michael Vigoda, Vicente Behrens, Nikola Miljkovic, Kris Arheart, and Richard Dutton

Abstract 6: Anesthesiology residents do not agree with their training programs on the degree to which the 2007 ACC/AHA guidelines are emphasized
BobbieJean Sweitzer, Michael Vigoda, Vicente Behrens, Nikola Miljkovic, and Kris Arheart

Abstract 7: Prevalence of obstructive sleep apnea in patients presenting for hip or knee replacement surgery
Micah Beachy, DO; Jason Shiffermiller, MD; and Chad Vokoun, MD

Abstract 8: A protocol to triage preoperative assessments to either nurses or nurse practitioners/physician assistants
Anthony Basil, RN; Pamela Pennigar, FNP; David R. Wright, MD; and Ronald P. Olson, MD

Abstract 9: Do ACEIs on the morning of surgery increase risk of intraoperative hypotension?
Steven L. Cohn, MD, and Kalia Skeete, MD

Abstract 10: One-year incidence of postoperative troponin revations in patients undergoing major orthopedic surgery
Michael Urban, MD, PhD; Stephen Wolfe, BS; Niel Sanghevi, BS; and Steven Magid, MD

Abstract 11: A review of preoperative clinic cardiology referrals for adults undergoing intermediate- and low-risk surgery
Susan Calderwood, MD; Jennifer Lee Morse, MS; and Damon R. Michaels, CCRP

Abstract 12: Patterns of preoperative consultation by risk and surgical specialty in a large health care system
Stephan Thilen, MD, MS; Christopher Bryson, MD, MS; Robert Reid, MD, PhD; and Miriam Treggiari, MD, MPH, PhD

Abstract 13: One-year incidence for admission to a critical care unit after major orthopedic surgery
Michael Urban, MD, PhD; Steven Magid, MD; and Michele Mangini, DNP

Abstract 14: Determination of the causes of long patient wait times in a preoperative evaluation clinic
Jean Kwo, MD; Devon Price, BS; Mary Elizabeth Ellbeg, RN; and Retsef Levi, PhD

Abstract 15: Does perioperative statin treatment affect hospital and ICU length of stay rollowing cardiac surgery: A systematic review
Vineet Chopra, MD, FACP, FHM; David Wesorick, MD; and Kim A. Eagle, MD

Abstract 16: Assessment of patient satisfaction of nurse screening vs complete preoperative assessment
Ronald Olson, MD, and Kathy Bock, RN

Abstract 17: Traumatic subdural hematoma: An update on morbidity
Rachel Thompson, MD; Christina Ryan, MD; Nancy Temkin, PhD; Richard Ellenbogen, MD; and Joann G. Elmore, MD, MPH

Abstract 18: Lipid emulsion as a lifesaving treatment for local anesthetic systemic toxicity (LAST)
Deepti Sachdev and Guy Weinberg, MD

Abstract 19: Perioperative ACLS recommendations should be modified for the treatment of local anesthetic toxicity
Adam Haas, MD, and Alexia Beccue, MD

Abstract 20: Preoperative EMR containing smart-set reminders improve accuracy of documentation by nonanesthesia clinicians during preoperative assessments
Angela Edwards, MD; Jill Grant, PA; and Ruth Hyde, MD

Abstract 21: POET: Procedure outcomes evaluation tool
Ahmad AbuSalah, MSc, and Terrence Adam, MD, PhD

Abstract 22: Results of a multidisciplinary preoperative assessment process for high-risk orthopedic patients
Terrence Adam, MD, PhD; Connie Parenti, MD; Terence Gioe, MD; and Karen Ringsred, MD

Abstract 23: Practical algorithm for preoperative evaluation of patients with liver disease
Madalina A. Vlase, PA-C, and Deborah C. Richman, MBChB, FFA(SA)

Abstract 24: Evaluation and management of isolated elevated aPTT
Sheila Hassan, MSN, NP; Patricia Kidik, MSN, NP; Catherine McGowan, MSN, NP; and Angela M. Bader, MD

Abstract 25: A perioperative triage plan for obstructive sleep apnea patients
Christian Altman, MD; R. Michael Boyer, DO; and Peter G. Kallas, MD

Abstract 26: Quantitative evaluation of handoff checklists
Jay Joshi, MD, and David Mayer, MD

Abstract 27: To deflate or not to deflate: Lap-Band® management in subsequent surgeries
Arjun Reddy, MD, and Deborah C. Richman, MBChB, FFA(SA)

Abstract 28: Takotsubo cardiomyopathy and resultant cardiogenic shock after mitral valve repair
Adam Evans, MD, MBA; Daniel B. Sims, MD; Nir Uriel, MD; Ulrich P. Jorde, MD; and Craig R. Smith, MD

Abstract 29: Intravenous vitamin K: Rapid reversal of warfarin and lack of subsequent warfarin resistance
Feras Abdul Khalek, MD; Interdeep Dhaliwal, MD; and Twylla Tassava, MD

Abstract 30: Cervical spine surgery: When not to extubate postoperatively
Carlos Mateo Mijares, MD; Doris Debs, ARNP, MSN-BC; Nicole Martin, MD; and Ronald Lee Samson, MD

Abstract 31: Total occlusion of oral cavity by mandibular sarcoma for resection: To intubate nasally or proceed to an awake tracheostomy?
Carlos Mateo Mijares, MD, and Maria DeLapena, MD

Abstract 32: Perioperative fatal embolic stroke associated with iron deficiency anemia and thrombocytosis
Carlos Mateo Mijares, MD; Nicole Martin, MD; and Ricardo Martinez-Ruiz, MD

Abstract 33: Conservative approach saves the day anesthesia-wise and surgical-wise
Carlos Mateo Mijares, MD; Bradley Shore, MD; Edward Zalkind, CRNA; and Nicole Martin, MD

Abstract 34: Predictors of acute kidney injury in patients undergoing total knee replacement surgery
Vishal Sehgal, MD; Pardeep Bansal, MD; Praveen Reddy, MD; Vishal Sharma, MD; Samuel Lesko, MD; John H. Doherty, MD; Theodore Tomaszewski, MD; Jack Prior, MD; Roger Getts, MD; and Jeremiah Eagan, MD

Abstract 35: Perioperative medical management of the Marfan patient undergoing repeat cardiothoracic surgery
Aashish Shah, MD, and Adam Skrzynski, MD

Index of abstract authors

A supplement to Clinical Psychiatry News and supported by Pfizer, Inc.
A panel of experts met in November 2005 in Washington, DC, to discuss the first published results of the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) schizophrenia study. Participants included several principal study investigators as well as experts in the treatment and management of schizophrenia and bipolar illness. The content of this supplement is based in part on that discussion.

•Faculty
•Topics

Peter F. Buckley, MD
Medical College of Georgia
School of Medicine
Grant/Research Support: Astra/Zeneca, Bristol-Myers Squibb Company, Eli Lilly and Company, Janssen Pharmaceutica, LP, Pfizer Inc., and Solvay Pharmaceuticals, Inc. Consultant/Received Honoraria: Abbott Laboratories, Alamo Pharmaceuticals, LLC, AstraZeneca, Bristol-Myers Squibb, Eli Lilly, Janssen, and Pfizer.

Joseph P. McEvoy, MD
Duke University
Medical Center
Clinical Grant Support: AstraZeneca, Bristol-Myers Squibb, Eli Lilly, Janssen, and Pfizer Inc. Consultant: GlaxoSmithKline, Eli Lilly, and Pfizer.

Topics

• Design
• Overview of Results
• Dosing
• Metabolics
• Clinical Implications of CATIE Phase I
• Beyond Phase I
• Implications of CATIE Beyond Schizophrenia
• Conclusion

A supplement to Clinical Psychiatry News and supported by Pfizer, Inc.
A panel of experts met in November 2005 in Washington, DC, to discuss the first published results of the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) schizophrenia study. Participants included several principal study investigators as well as experts in the treatment and management of schizophrenia and bipolar illness. The content of this supplement is based in part on that discussion.

•Faculty
•Topics

Peter F. Buckley, MD
Medical College of Georgia
School of Medicine
Grant/Research Support: Astra/Zeneca, Bristol-Myers Squibb Company, Eli Lilly and Company, Janssen Pharmaceutica, LP, Pfizer Inc., and Solvay Pharmaceuticals, Inc. Consultant/Received Honoraria: Abbott Laboratories, Alamo Pharmaceuticals, LLC, AstraZeneca, Bristol-Myers Squibb, Eli Lilly, Janssen, and Pfizer.

Joseph P. McEvoy, MD
Duke University
Medical Center
Clinical Grant Support: AstraZeneca, Bristol-Myers Squibb, Eli Lilly, Janssen, and Pfizer Inc. Consultant: GlaxoSmithKline, Eli Lilly, and Pfizer.

Topics

• Design
• Overview of Results
• Dosing
• Metabolics
• Clinical Implications of CATIE Phase I
• Beyond Phase I
• Implications of CATIE Beyond Schizophrenia
• Conclusion

A supplement to Clinical Psychiatry News and supported by Pfizer, Inc.
A panel of experts met in November 2005 in Washington, DC, to discuss the first published results of the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) schizophrenia study. Participants included several principal study investigators as well as experts in the treatment and management of schizophrenia and bipolar illness. The content of this supplement is based in part on that discussion.

•Faculty
•Topics

Peter F. Buckley, MD
Medical College of Georgia
School of Medicine
Grant/Research Support: Astra/Zeneca, Bristol-Myers Squibb Company, Eli Lilly and Company, Janssen Pharmaceutica, LP, Pfizer Inc., and Solvay Pharmaceuticals, Inc. Consultant/Received Honoraria: Abbott Laboratories, Alamo Pharmaceuticals, LLC, AstraZeneca, Bristol-Myers Squibb, Eli Lilly, Janssen, and Pfizer.

Joseph P. McEvoy, MD
Duke University
Medical Center
Clinical Grant Support: AstraZeneca, Bristol-Myers Squibb, Eli Lilly, Janssen, and Pfizer Inc. Consultant: GlaxoSmithKline, Eli Lilly, and Pfizer.

Topics

• Design
• Overview of Results
• Dosing
• Metabolics
• Clinical Implications of CATIE Phase I
• Beyond Phase I
• Implications of CATIE Beyond Schizophrenia
• Conclusion

A supplement to Clinical Psychiatry News.
This CLINICAL UPDATE is supported by Takeda Pharmaceuticals North America, Inc.

•Introduction
•Topic Highlights

Introduction
Roland R. Griffiths, PhD
Professor of Behavioral Biology
Departments of Psychiatry and Neuroscience
Johns Hopkins University
School of Medicine
Baltimore, Md.
Dr. Griffiths has disclosed that he is Principal Investigator of two grants from the National Institute on Drug Abuse (NIDA) (R01 DA03889 and R01 DA03890) and co-investigator on a contract and several other grants from NIDA. During the past 5 years, on issues about drug abuse liability, he has been a consultant to or received grants from the following pharmaceutical companies: Abbott Laboratories, Forest Laboratories Inc., Merck & Co., Inc., Neurocrine Biosciences, Inc., Novartis Pharmaceuticals Corporation, Orphan Medical, Pharmacia Corporation, Pfizer Inc., Takeda Pharmaceuticals, TransOral Pharmaceucticals, Inc., Somaxon Pharmaceuticals Inc., and Wyeth Pharmaceuticals. He has disclosed that he will be discussing non-medical use (ie, abuse) of various hypnotic drugs.

Topic Highlights

• Abuse Potential of Sleeping Agents: Liability Varies Among Agents
Insomnia: A Brief Review
Effects of Insomnia
Pharmacologic Treatment of Insomnia
Patterns of Sedative/Hypnotic Abuse

• Abuse Potential of Hypnotic Agents: Study Evaluates Relative Abuse Liability
Defining Relative Abuse Liability and Toxicity
Relative Abuse Liability Table
Results of Analysis

Copyright © 2006 Elsevier Inc.

A supplement to Clinical Psychiatry News.
This CLINICAL UPDATE is supported by Takeda Pharmaceuticals North America, Inc.

•Introduction
•Topic Highlights

Introduction
Roland R. Griffiths, PhD
Professor of Behavioral Biology
Departments of Psychiatry and Neuroscience
Johns Hopkins University
School of Medicine
Baltimore, Md.
Dr. Griffiths has disclosed that he is Principal Investigator of two grants from the National Institute on Drug Abuse (NIDA) (R01 DA03889 and R01 DA03890) and co-investigator on a contract and several other grants from NIDA. During the past 5 years, on issues about drug abuse liability, he has been a consultant to or received grants from the following pharmaceutical companies: Abbott Laboratories, Forest Laboratories Inc., Merck & Co., Inc., Neurocrine Biosciences, Inc., Novartis Pharmaceuticals Corporation, Orphan Medical, Pharmacia Corporation, Pfizer Inc., Takeda Pharmaceuticals, TransOral Pharmaceucticals, Inc., Somaxon Pharmaceuticals Inc., and Wyeth Pharmaceuticals. He has disclosed that he will be discussing non-medical use (ie, abuse) of various hypnotic drugs.

Topic Highlights

• Abuse Potential of Sleeping Agents: Liability Varies Among Agents
Insomnia: A Brief Review
Effects of Insomnia
Pharmacologic Treatment of Insomnia
Patterns of Sedative/Hypnotic Abuse

• Abuse Potential of Hypnotic Agents: Study Evaluates Relative Abuse Liability
Defining Relative Abuse Liability and Toxicity
Relative Abuse Liability Table
Results of Analysis

Copyright © 2006 Elsevier Inc.

A supplement to Clinical Psychiatry News.
This CLINICAL UPDATE is supported by Takeda Pharmaceuticals North America, Inc.

•Introduction
•Topic Highlights

Introduction
Roland R. Griffiths, PhD
Professor of Behavioral Biology
Departments of Psychiatry and Neuroscience
Johns Hopkins University
School of Medicine
Baltimore, Md.
Dr. Griffiths has disclosed that he is Principal Investigator of two grants from the National Institute on Drug Abuse (NIDA) (R01 DA03889 and R01 DA03890) and co-investigator on a contract and several other grants from NIDA. During the past 5 years, on issues about drug abuse liability, he has been a consultant to or received grants from the following pharmaceutical companies: Abbott Laboratories, Forest Laboratories Inc., Merck & Co., Inc., Neurocrine Biosciences, Inc., Novartis Pharmaceuticals Corporation, Orphan Medical, Pharmacia Corporation, Pfizer Inc., Takeda Pharmaceuticals, TransOral Pharmaceucticals, Inc., Somaxon Pharmaceuticals Inc., and Wyeth Pharmaceuticals. He has disclosed that he will be discussing non-medical use (ie, abuse) of various hypnotic drugs.

Topic Highlights

• Abuse Potential of Sleeping Agents: Liability Varies Among Agents
Insomnia: A Brief Review
Effects of Insomnia
Pharmacologic Treatment of Insomnia
Patterns of Sedative/Hypnotic Abuse

• Abuse Potential of Hypnotic Agents: Study Evaluates Relative Abuse Liability
Defining Relative Abuse Liability and Toxicity
Relative Abuse Liability Table
Results of Analysis

Copyright © 2006 Elsevier Inc.

This CLINICAL UPDATE is supported by an educational grant from UCB Pharma, Inc., and is a supplement to Clinical Psychiatry News.
This supplement is based on a faculty interview and poster reviews.

•Faculty
•Topics

Click Here To view the supplement.

Faculty

Joseph F. Goldberg, MD
Director of Bipolar Disorders Research
The Zucker Hillside Hospital-North Shore Long Island Jewish Health System
Glen Oaks, N.Y.
Received Funding for Clinical Grants/Consultant: Abbott Laboratories, AstraZeneca, Bristol-Myers Squibb Company, Eli Lilly and Company, and GlaxoSmithKline. He discusses the off-label use of levetiracetam for the treatment of psychiatric disorders.

Topics

• Anticonvulsants and Psychiatric Disorders

• Treatment of Varied Psychiatric Disorders in an Outpatient Setting

• Prevalence of ADHD in Adults

• Treatment of Mild or Moderate Bipolar Disorder

• Prevalence of Medical Comorbidity in Severe Psychiatric Disorders

• Evaluation of Therapy for Aggression Disorders

• Prevalence of Comorbid Anxiety Disorders

• Evaluation of Therapy for Bipolar Mania

• Evaluation of Add-On Therapy for Bipolar Disorder Therapy

Copyright © 2004 by International Medical News Group

This CLINICAL UPDATE is supported by an educational grant from UCB Pharma, Inc., and is a supplement to Clinical Psychiatry News.
This supplement is based on a faculty interview and poster reviews.

•Faculty
•Topics

Click Here To view the supplement.

Faculty

Joseph F. Goldberg, MD
Director of Bipolar Disorders Research
The Zucker Hillside Hospital-North Shore Long Island Jewish Health System
Glen Oaks, N.Y.
Received Funding for Clinical Grants/Consultant: Abbott Laboratories, AstraZeneca, Bristol-Myers Squibb Company, Eli Lilly and Company, and GlaxoSmithKline. He discusses the off-label use of levetiracetam for the treatment of psychiatric disorders.

Topics

• Anticonvulsants and Psychiatric Disorders

• Treatment of Varied Psychiatric Disorders in an Outpatient Setting

• Prevalence of ADHD in Adults

• Treatment of Mild or Moderate Bipolar Disorder

• Prevalence of Medical Comorbidity in Severe Psychiatric Disorders

• Evaluation of Therapy for Aggression Disorders

• Prevalence of Comorbid Anxiety Disorders

• Evaluation of Therapy for Bipolar Mania

• Evaluation of Add-On Therapy for Bipolar Disorder Therapy

Copyright © 2004 by International Medical News Group

This CLINICAL UPDATE is supported by an educational grant from UCB Pharma, Inc., and is a supplement to Clinical Psychiatry News.
This supplement is based on a faculty interview and poster reviews.

•Faculty
•Topics

Click Here To view the supplement.

Faculty

Joseph F. Goldberg, MD
Director of Bipolar Disorders Research
The Zucker Hillside Hospital-North Shore Long Island Jewish Health System
Glen Oaks, N.Y.
Received Funding for Clinical Grants/Consultant: Abbott Laboratories, AstraZeneca, Bristol-Myers Squibb Company, Eli Lilly and Company, and GlaxoSmithKline. He discusses the off-label use of levetiracetam for the treatment of psychiatric disorders.

Topics

• Anticonvulsants and Psychiatric Disorders

• Treatment of Varied Psychiatric Disorders in an Outpatient Setting

• Prevalence of ADHD in Adults

• Treatment of Mild or Moderate Bipolar Disorder

• Prevalence of Medical Comorbidity in Severe Psychiatric Disorders

• Evaluation of Therapy for Aggression Disorders

• Prevalence of Comorbid Anxiety Disorders

• Evaluation of Therapy for Bipolar Mania

• Evaluation of Add-On Therapy for Bipolar Disorder Therapy

Copyright © 2004 by International Medical News Group

A supplement to Skin & Allergy News. This supplement was sponsored by Galderma Laboratories, L.P.

​

• NRS Digital Perception Survey
• Presentation And Diagnosis
• Treatment Strategies

Faculty/Faculty Disclosure

Debra B. Luftman, MD
Coauthor of The Beauty Prescription:
The Complete Formula for Looking and Feeling Beautiful Calabasas, California
Dr Luftman has received funding for clinical grants from and is a consultant for Galderma Laboratories, L.P.

Copyright (c) 2011 Elsevier Inc.

To view the supplement, click the image above.

A supplement to Skin & Allergy News. This supplement was sponsored by Galderma Laboratories, L.P.

​

• NRS Digital Perception Survey
• Presentation And Diagnosis
• Treatment Strategies

Faculty/Faculty Disclosure

Debra B. Luftman, MD
Coauthor of The Beauty Prescription:
The Complete Formula for Looking and Feeling Beautiful Calabasas, California
Dr Luftman has received funding for clinical grants from and is a consultant for Galderma Laboratories, L.P.

Copyright (c) 2011 Elsevier Inc.

To view the supplement, click the image above.

A supplement to Skin & Allergy News. This supplement was sponsored by Galderma Laboratories, L.P.

​

• NRS Digital Perception Survey
• Presentation And Diagnosis
• Treatment Strategies

Faculty/Faculty Disclosure

Debra B. Luftman, MD
Coauthor of The Beauty Prescription:
The Complete Formula for Looking and Feeling Beautiful Calabasas, California
Dr Luftman has received funding for clinical grants from and is a consultant for Galderma Laboratories, L.P.

Copyright (c) 2011 Elsevier Inc.

To view the supplement, click the image above.