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Key clinical point: Helicobacter pylori (HP) infection is associated with the tumor expression of programmed death ligand-1 (PD-L1) in patients with gastric cancer.
Major finding: HP infection was significantly associated with the tumor expression of PD-L1 in patients with gastric cancer (odds ratio 1.90; P < .001), with the association not being significantly affected by the sample size, evaluation methods for PD-L1 expression, or quality score (all P > .05).
Study details: This meta-analysis of 10 observational studies investigated the association between HP infection and the tumor expression of PD-L1 in 1870 patients with gastric cancer.
Disclosures: This study was sponsored by the Natural Science Foundation of the Anhui Higher Education Institutions of China and others. The authors declared no conflicts of interest.
Source: Zhu Y et al. Helicobacter pylori infection and PD-L1 expression in gastric cancer: A meta-analysis. Eur J Clin Invest. 2022:e13880 (Sep 27). Doi: 10.1111/eci.13880
Key clinical point: Helicobacter pylori (HP) infection is associated with the tumor expression of programmed death ligand-1 (PD-L1) in patients with gastric cancer.
Major finding: HP infection was significantly associated with the tumor expression of PD-L1 in patients with gastric cancer (odds ratio 1.90; P < .001), with the association not being significantly affected by the sample size, evaluation methods for PD-L1 expression, or quality score (all P > .05).
Study details: This meta-analysis of 10 observational studies investigated the association between HP infection and the tumor expression of PD-L1 in 1870 patients with gastric cancer.
Disclosures: This study was sponsored by the Natural Science Foundation of the Anhui Higher Education Institutions of China and others. The authors declared no conflicts of interest.
Source: Zhu Y et al. Helicobacter pylori infection and PD-L1 expression in gastric cancer: A meta-analysis. Eur J Clin Invest. 2022:e13880 (Sep 27). Doi: 10.1111/eci.13880
Key clinical point: Helicobacter pylori (HP) infection is associated with the tumor expression of programmed death ligand-1 (PD-L1) in patients with gastric cancer.
Major finding: HP infection was significantly associated with the tumor expression of PD-L1 in patients with gastric cancer (odds ratio 1.90; P < .001), with the association not being significantly affected by the sample size, evaluation methods for PD-L1 expression, or quality score (all P > .05).
Study details: This meta-analysis of 10 observational studies investigated the association between HP infection and the tumor expression of PD-L1 in 1870 patients with gastric cancer.
Disclosures: This study was sponsored by the Natural Science Foundation of the Anhui Higher Education Institutions of China and others. The authors declared no conflicts of interest.
Source: Zhu Y et al. Helicobacter pylori infection and PD-L1 expression in gastric cancer: A meta-analysis. Eur J Clin Invest. 2022:e13880 (Sep 27). Doi: 10.1111/eci.13880