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Key clinical point: Dietary iron shows an inverse association with the risk for gastric cancer irrespective of cancer subsite and histological type.

Major finding: Dietary iron intake was inversely associated with the risk for gastric cancer (per quartile odds ratio [OR] 0.88; 95% CI 0.83-0.93). The association (per quartile) was significant for cardia (OR 0.85; 95% CI 0.77-0.94) and noncardia (OR 0.87; 95% CI 0.81-0.94) gastric cancer and diffuse (OR,0.79; 95% CI 0.69-0.89) and intestinal (OR 0.88; 95% CI 0.79-0.98) type.

Study details: An analysis of pooled data from 11 case-control studies including 4658 participants with gastric cancer and 12,247 control participants from the Stomach Cancer Pooling Project.

Disclosures: This study was supported by AIRC Foundation for Cancer Research, Italy. The authors declared no conflicts of interest.

Source: Collatuzzo G et al. Inverse association between dietary iron intake and gastric cancer: A pooled analysis of case-control studies of the stop consortium. Nutrients. 2022;14(12):2555 (Jun 20). Doi: 10.3390/nu14122555

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Key clinical point: Dietary iron shows an inverse association with the risk for gastric cancer irrespective of cancer subsite and histological type.

Major finding: Dietary iron intake was inversely associated with the risk for gastric cancer (per quartile odds ratio [OR] 0.88; 95% CI 0.83-0.93). The association (per quartile) was significant for cardia (OR 0.85; 95% CI 0.77-0.94) and noncardia (OR 0.87; 95% CI 0.81-0.94) gastric cancer and diffuse (OR,0.79; 95% CI 0.69-0.89) and intestinal (OR 0.88; 95% CI 0.79-0.98) type.

Study details: An analysis of pooled data from 11 case-control studies including 4658 participants with gastric cancer and 12,247 control participants from the Stomach Cancer Pooling Project.

Disclosures: This study was supported by AIRC Foundation for Cancer Research, Italy. The authors declared no conflicts of interest.

Source: Collatuzzo G et al. Inverse association between dietary iron intake and gastric cancer: A pooled analysis of case-control studies of the stop consortium. Nutrients. 2022;14(12):2555 (Jun 20). Doi: 10.3390/nu14122555

Key clinical point: Dietary iron shows an inverse association with the risk for gastric cancer irrespective of cancer subsite and histological type.

Major finding: Dietary iron intake was inversely associated with the risk for gastric cancer (per quartile odds ratio [OR] 0.88; 95% CI 0.83-0.93). The association (per quartile) was significant for cardia (OR 0.85; 95% CI 0.77-0.94) and noncardia (OR 0.87; 95% CI 0.81-0.94) gastric cancer and diffuse (OR,0.79; 95% CI 0.69-0.89) and intestinal (OR 0.88; 95% CI 0.79-0.98) type.

Study details: An analysis of pooled data from 11 case-control studies including 4658 participants with gastric cancer and 12,247 control participants from the Stomach Cancer Pooling Project.

Disclosures: This study was supported by AIRC Foundation for Cancer Research, Italy. The authors declared no conflicts of interest.

Source: Collatuzzo G et al. Inverse association between dietary iron intake and gastric cancer: A pooled analysis of case-control studies of the stop consortium. Nutrients. 2022;14(12):2555 (Jun 20). Doi: 10.3390/nu14122555

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Clinical Edge Journal Scan: Gastric Cancer, August 2022
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