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Tuberculosis Management: Returning to Pre-Pandemic Priorities
- Global tuberculosis report 2022. World Health Organization. Published October 27, 2022. Accessed June 26, 2023. https://www.who.int/publications/i/item/9789240061729
- WHO consolidated guidelines on tuberculosis. Module 4: treatment – drug-resistant tuberculosis treatment, 2022 update. World Health Organization. Published December 15, 2022. Accessed June 26, 2023. https://www.who.int/publications/i/item/9789240063129
- Migliori GB, Tiberi S. Int J Tuberc Lung Dis. 2022 ;26(7):590-591. doi:10.5588/ijtld.22.0263.
- Lange C et al. Am J Respir Crit Care Med. 2022;205(10):1142-1144. doi:10.1164/rccm.202202-0393ED
- Esmail A et al. Am J Respir Crit Care Med. 2022;205(10):1214-1227. doi:10.1164/rccm.202107-1779OC
- WHO BPaLM Accelerator Platform: to support the call to action for implementation of the shorter and more effective treatment for all people suffering from drug-resistant TB. World Health Organization. Published May 9, 2023. Accessed June 26, 2023. https://www.who.int/news-room/events/detail/2023/05/09/default-calendar/who-bpalm-accelerator-platform–to-support-the-call-to-action-for-implementation-of-the-shorter-and-moreeffective-
- Trevisi L et al. Am J Respir Crit Care Med. 2023;207(11):1525-1532. doi:10.1164/rccm.202211-2125OC
- Domínguez J et al; TBnet and RESIST-TB networks. Lancet Infect Dis. 2023;23(4):e122-e137. doi:10.1016/S1473-3099(22)00875-1
- WHO operational handbook on tuberculosis: module 3: diagnosis: rapid diagnostics for tuberculosis detection, 2021 update. World Health Organization. Published July 7, 2021. Accessed June 26, 2023. https://www.who.int/publications/i/item/9789240030589treatment-for-all-people-suffering-from-drug-resistant-tb
- Global tuberculosis report 2022. World Health Organization. Published October 27, 2022. Accessed June 26, 2023. https://www.who.int/publications/i/item/9789240061729
- WHO consolidated guidelines on tuberculosis. Module 4: treatment – drug-resistant tuberculosis treatment, 2022 update. World Health Organization. Published December 15, 2022. Accessed June 26, 2023. https://www.who.int/publications/i/item/9789240063129
- Migliori GB, Tiberi S. Int J Tuberc Lung Dis. 2022 ;26(7):590-591. doi:10.5588/ijtld.22.0263.
- Lange C et al. Am J Respir Crit Care Med. 2022;205(10):1142-1144. doi:10.1164/rccm.202202-0393ED
- Esmail A et al. Am J Respir Crit Care Med. 2022;205(10):1214-1227. doi:10.1164/rccm.202107-1779OC
- WHO BPaLM Accelerator Platform: to support the call to action for implementation of the shorter and more effective treatment for all people suffering from drug-resistant TB. World Health Organization. Published May 9, 2023. Accessed June 26, 2023. https://www.who.int/news-room/events/detail/2023/05/09/default-calendar/who-bpalm-accelerator-platform–to-support-the-call-to-action-for-implementation-of-the-shorter-and-moreeffective-
- Trevisi L et al. Am J Respir Crit Care Med. 2023;207(11):1525-1532. doi:10.1164/rccm.202211-2125OC
- Domínguez J et al; TBnet and RESIST-TB networks. Lancet Infect Dis. 2023;23(4):e122-e137. doi:10.1016/S1473-3099(22)00875-1
- WHO operational handbook on tuberculosis: module 3: diagnosis: rapid diagnostics for tuberculosis detection, 2021 update. World Health Organization. Published July 7, 2021. Accessed June 26, 2023. https://www.who.int/publications/i/item/9789240030589treatment-for-all-people-suffering-from-drug-resistant-tb
- Global tuberculosis report 2022. World Health Organization. Published October 27, 2022. Accessed June 26, 2023. https://www.who.int/publications/i/item/9789240061729
- WHO consolidated guidelines on tuberculosis. Module 4: treatment – drug-resistant tuberculosis treatment, 2022 update. World Health Organization. Published December 15, 2022. Accessed June 26, 2023. https://www.who.int/publications/i/item/9789240063129
- Migliori GB, Tiberi S. Int J Tuberc Lung Dis. 2022 ;26(7):590-591. doi:10.5588/ijtld.22.0263.
- Lange C et al. Am J Respir Crit Care Med. 2022;205(10):1142-1144. doi:10.1164/rccm.202202-0393ED
- Esmail A et al. Am J Respir Crit Care Med. 2022;205(10):1214-1227. doi:10.1164/rccm.202107-1779OC
- WHO BPaLM Accelerator Platform: to support the call to action for implementation of the shorter and more effective treatment for all people suffering from drug-resistant TB. World Health Organization. Published May 9, 2023. Accessed June 26, 2023. https://www.who.int/news-room/events/detail/2023/05/09/default-calendar/who-bpalm-accelerator-platform–to-support-the-call-to-action-for-implementation-of-the-shorter-and-moreeffective-
- Trevisi L et al. Am J Respir Crit Care Med. 2023;207(11):1525-1532. doi:10.1164/rccm.202211-2125OC
- Domínguez J et al; TBnet and RESIST-TB networks. Lancet Infect Dis. 2023;23(4):e122-e137. doi:10.1016/S1473-3099(22)00875-1
- WHO operational handbook on tuberculosis: module 3: diagnosis: rapid diagnostics for tuberculosis detection, 2021 update. World Health Organization. Published July 7, 2021. Accessed June 26, 2023. https://www.who.int/publications/i/item/9789240030589treatment-for-all-people-suffering-from-drug-resistant-tb
Addressing Physician Burnout in Pulmonology and Critical Care
- Moss M et al. Crit Care Med. 2016;44(7):1414-1421. doi:10.1097/CCM.000000000000188
- Medscape National Physician Burnout, Depression & Suicide Report 2019. Medscape. January 16, 2019. Accessed June 22, 2023. https://www.medscape.com/slideshow/2019-lifestyle-burnout-depression-6011056#1
- Medscape National Physician Burnout & Suicide Report 2020: The Generational Divide. Medscape. January 15, 2020. Accessed June 22, 2023. https://www.medscape.com/slideshow/2020-lifestyle-burnout-6012460#1
- ‘Death by 1000 Cuts’: Medscape National Physician Burnout & Suicide Report 2021. Medscape. January 22, 2021. Accessed June 22, 2023. https://www.medscape.com/slideshow/2021-lifestyle-burnout-6013456#2
- Physician Burnout Report 2022: Stress, Anxiety, and Anger. Medscape. January 21, 2022. Accessed June 22, 2023. https://www.medscape.com/slideshow/2022-lifestyle-burnout-6014664#1
- ‘I Cry but No One Cares’: Physician Burnout & Depression Report 2023. Medscape. January 27, 2023. Accessed June 22, 2023. https://www.medscape.com/slideshow/2023-lifestyle-burnout-6016058#1
- Murthy VH. N Engl J Med. 2022;387(7):577-579. doi:10.1056/NEJMp2207252
- Vranas KC et al. Chest. 2021;160(5):1714-1728. doi:10.1016/j.chest.2021.05.041
- Kerlin MP et al. Ann Am Thorac Soc. 2022;19(2):329-331. doi:10.1513/AnnalsATS.202105-567RL
- Dean W et al. Fed Pract. 2019;36(9):400-402. PMID: 31571807
- Association of American Medical Colleges. The Complexities of Physician Supply and Demand: Projections from 2019 to 2034. June 2021. https://www.aamc.org/media/54681/download?attachment
- Medscape Pulmonologist Lifestyle, Happiness & Burnout Report 2023: Contentment Amid Stress. February 24, 2023. Accessed June 28, 2023. https://www.medscape.com/slideshow/2023-lifestyle-pulmonologist-6016092#1
- Medscape Intensivist Lifestyle, Happiness & Burnout Report 2023: Contentment Amid Stress. February 24, 2023. Accessed June 28, 2023. https://www.medscape.com/slideshow/2023-lifestyle-intensivist-6016072#1
- Moss M et al. Crit Care Med. 2016;44(7):1414-1421. doi:10.1097/CCM.000000000000188
- Medscape National Physician Burnout, Depression & Suicide Report 2019. Medscape. January 16, 2019. Accessed June 22, 2023. https://www.medscape.com/slideshow/2019-lifestyle-burnout-depression-6011056#1
- Medscape National Physician Burnout & Suicide Report 2020: The Generational Divide. Medscape. January 15, 2020. Accessed June 22, 2023. https://www.medscape.com/slideshow/2020-lifestyle-burnout-6012460#1
- ‘Death by 1000 Cuts’: Medscape National Physician Burnout & Suicide Report 2021. Medscape. January 22, 2021. Accessed June 22, 2023. https://www.medscape.com/slideshow/2021-lifestyle-burnout-6013456#2
- Physician Burnout Report 2022: Stress, Anxiety, and Anger. Medscape. January 21, 2022. Accessed June 22, 2023. https://www.medscape.com/slideshow/2022-lifestyle-burnout-6014664#1
- ‘I Cry but No One Cares’: Physician Burnout & Depression Report 2023. Medscape. January 27, 2023. Accessed June 22, 2023. https://www.medscape.com/slideshow/2023-lifestyle-burnout-6016058#1
- Murthy VH. N Engl J Med. 2022;387(7):577-579. doi:10.1056/NEJMp2207252
- Vranas KC et al. Chest. 2021;160(5):1714-1728. doi:10.1016/j.chest.2021.05.041
- Kerlin MP et al. Ann Am Thorac Soc. 2022;19(2):329-331. doi:10.1513/AnnalsATS.202105-567RL
- Dean W et al. Fed Pract. 2019;36(9):400-402. PMID: 31571807
- Association of American Medical Colleges. The Complexities of Physician Supply and Demand: Projections from 2019 to 2034. June 2021. https://www.aamc.org/media/54681/download?attachment
- Medscape Pulmonologist Lifestyle, Happiness & Burnout Report 2023: Contentment Amid Stress. February 24, 2023. Accessed June 28, 2023. https://www.medscape.com/slideshow/2023-lifestyle-pulmonologist-6016092#1
- Medscape Intensivist Lifestyle, Happiness & Burnout Report 2023: Contentment Amid Stress. February 24, 2023. Accessed June 28, 2023. https://www.medscape.com/slideshow/2023-lifestyle-intensivist-6016072#1
- Moss M et al. Crit Care Med. 2016;44(7):1414-1421. doi:10.1097/CCM.000000000000188
- Medscape National Physician Burnout, Depression & Suicide Report 2019. Medscape. January 16, 2019. Accessed June 22, 2023. https://www.medscape.com/slideshow/2019-lifestyle-burnout-depression-6011056#1
- Medscape National Physician Burnout & Suicide Report 2020: The Generational Divide. Medscape. January 15, 2020. Accessed June 22, 2023. https://www.medscape.com/slideshow/2020-lifestyle-burnout-6012460#1
- ‘Death by 1000 Cuts’: Medscape National Physician Burnout & Suicide Report 2021. Medscape. January 22, 2021. Accessed June 22, 2023. https://www.medscape.com/slideshow/2021-lifestyle-burnout-6013456#2
- Physician Burnout Report 2022: Stress, Anxiety, and Anger. Medscape. January 21, 2022. Accessed June 22, 2023. https://www.medscape.com/slideshow/2022-lifestyle-burnout-6014664#1
- ‘I Cry but No One Cares’: Physician Burnout & Depression Report 2023. Medscape. January 27, 2023. Accessed June 22, 2023. https://www.medscape.com/slideshow/2023-lifestyle-burnout-6016058#1
- Murthy VH. N Engl J Med. 2022;387(7):577-579. doi:10.1056/NEJMp2207252
- Vranas KC et al. Chest. 2021;160(5):1714-1728. doi:10.1016/j.chest.2021.05.041
- Kerlin MP et al. Ann Am Thorac Soc. 2022;19(2):329-331. doi:10.1513/AnnalsATS.202105-567RL
- Dean W et al. Fed Pract. 2019;36(9):400-402. PMID: 31571807
- Association of American Medical Colleges. The Complexities of Physician Supply and Demand: Projections from 2019 to 2034. June 2021. https://www.aamc.org/media/54681/download?attachment
- Medscape Pulmonologist Lifestyle, Happiness & Burnout Report 2023: Contentment Amid Stress. February 24, 2023. Accessed June 28, 2023. https://www.medscape.com/slideshow/2023-lifestyle-pulmonologist-6016092#1
- Medscape Intensivist Lifestyle, Happiness & Burnout Report 2023: Contentment Amid Stress. February 24, 2023. Accessed June 28, 2023. https://www.medscape.com/slideshow/2023-lifestyle-intensivist-6016072#1
Enlarging pink patches after traveling
The patient’s multiple pink, subtly annular patches after recent travel to Lyme-endemic areas of the United States demonstrated a classic manifestation of disseminated Lyme disease. An enzyme-linked immunosorbent assay was positive for Borrelia burgdorferi IgM and IgG antibodies, confirming an acute infection.
While not usually necessary, skin biopsy shows a nonspecific perivascular cellular infiltrate that may be comprised of histiocytes, lymphocytes, and plasma cells. Spirochetes are not typically seen, but they may be identified with antibody-labeled or silver stains.
Lyme disease initially manifests as localized disease with erythema migrans, a targetoid lesion on the skin that appears at the site of the tick bite. This initial stage develops within the first few weeks of the bite and may be accompanied by fatigue and a low-grade fever.
If left untreated, the infection may progress to early disseminated disease, which occurs weeks to months after the initial bite. This second stage of Lyme disease manifests with multiple erythema migrans lesions on additional parts of the body, indicating spirochete dissemination through the bloodstream and lymphatic system. Early disseminated disease may also include borrelial lymphocytoma, Lyme neuroborreliosis, and cardiac conduction abnormalities such as AV block.
The third stage of Lyme disease, late Lyme disease, occurs months to years after an initial infection that has gone untreated. The key feature of this stage is arthritis, which tends to affect the knees and may be migratory in nature. Neurological symptoms such as encephalopathy and polyneuropathies may also develop. A minority of patients with late Lyme disease may develop acrodermatitis chronica atrophicans, a rash that typically occurs on the dorsal hands and feet as blue-red plaques that turn the affected skin atrophic.1
This patient was treated with a 3-week course of oral doxycycline 100 mg twice daily and was referred to an infectious disease specialist for further work-up of systemic symptoms, given the risk for cardiac pathology in disseminated Lyme disease.
Photo courtesy of Le Wen Chiu, MD. Text courtesy of Le Wen Chiu, MD, Department of Dermatology, University of New Mexico School of Medicine, Albuquerque, and Daniel Stulberg, MD, FAAFP, Professor and Chair, Department of Family and Community Medicine, Western Michigan University Homer Stryker, MD School of Medicine, Kalamazoo.
1. Cardenas-de la Garza JA, De la Cruz-Valadez E, Ocampo-Candiani J, et al. Clinical spectrum of Lyme disease. Eur J Clin Microbiol Infect Dis. 2019;38:201-208. doi:10.1007/s10096-018-3417-1
The patient’s multiple pink, subtly annular patches after recent travel to Lyme-endemic areas of the United States demonstrated a classic manifestation of disseminated Lyme disease. An enzyme-linked immunosorbent assay was positive for Borrelia burgdorferi IgM and IgG antibodies, confirming an acute infection.
While not usually necessary, skin biopsy shows a nonspecific perivascular cellular infiltrate that may be comprised of histiocytes, lymphocytes, and plasma cells. Spirochetes are not typically seen, but they may be identified with antibody-labeled or silver stains.
Lyme disease initially manifests as localized disease with erythema migrans, a targetoid lesion on the skin that appears at the site of the tick bite. This initial stage develops within the first few weeks of the bite and may be accompanied by fatigue and a low-grade fever.
If left untreated, the infection may progress to early disseminated disease, which occurs weeks to months after the initial bite. This second stage of Lyme disease manifests with multiple erythema migrans lesions on additional parts of the body, indicating spirochete dissemination through the bloodstream and lymphatic system. Early disseminated disease may also include borrelial lymphocytoma, Lyme neuroborreliosis, and cardiac conduction abnormalities such as AV block.
The third stage of Lyme disease, late Lyme disease, occurs months to years after an initial infection that has gone untreated. The key feature of this stage is arthritis, which tends to affect the knees and may be migratory in nature. Neurological symptoms such as encephalopathy and polyneuropathies may also develop. A minority of patients with late Lyme disease may develop acrodermatitis chronica atrophicans, a rash that typically occurs on the dorsal hands and feet as blue-red plaques that turn the affected skin atrophic.1
This patient was treated with a 3-week course of oral doxycycline 100 mg twice daily and was referred to an infectious disease specialist for further work-up of systemic symptoms, given the risk for cardiac pathology in disseminated Lyme disease.
Photo courtesy of Le Wen Chiu, MD. Text courtesy of Le Wen Chiu, MD, Department of Dermatology, University of New Mexico School of Medicine, Albuquerque, and Daniel Stulberg, MD, FAAFP, Professor and Chair, Department of Family and Community Medicine, Western Michigan University Homer Stryker, MD School of Medicine, Kalamazoo.
The patient’s multiple pink, subtly annular patches after recent travel to Lyme-endemic areas of the United States demonstrated a classic manifestation of disseminated Lyme disease. An enzyme-linked immunosorbent assay was positive for Borrelia burgdorferi IgM and IgG antibodies, confirming an acute infection.
While not usually necessary, skin biopsy shows a nonspecific perivascular cellular infiltrate that may be comprised of histiocytes, lymphocytes, and plasma cells. Spirochetes are not typically seen, but they may be identified with antibody-labeled or silver stains.
Lyme disease initially manifests as localized disease with erythema migrans, a targetoid lesion on the skin that appears at the site of the tick bite. This initial stage develops within the first few weeks of the bite and may be accompanied by fatigue and a low-grade fever.
If left untreated, the infection may progress to early disseminated disease, which occurs weeks to months after the initial bite. This second stage of Lyme disease manifests with multiple erythema migrans lesions on additional parts of the body, indicating spirochete dissemination through the bloodstream and lymphatic system. Early disseminated disease may also include borrelial lymphocytoma, Lyme neuroborreliosis, and cardiac conduction abnormalities such as AV block.
The third stage of Lyme disease, late Lyme disease, occurs months to years after an initial infection that has gone untreated. The key feature of this stage is arthritis, which tends to affect the knees and may be migratory in nature. Neurological symptoms such as encephalopathy and polyneuropathies may also develop. A minority of patients with late Lyme disease may develop acrodermatitis chronica atrophicans, a rash that typically occurs on the dorsal hands and feet as blue-red plaques that turn the affected skin atrophic.1
This patient was treated with a 3-week course of oral doxycycline 100 mg twice daily and was referred to an infectious disease specialist for further work-up of systemic symptoms, given the risk for cardiac pathology in disseminated Lyme disease.
Photo courtesy of Le Wen Chiu, MD. Text courtesy of Le Wen Chiu, MD, Department of Dermatology, University of New Mexico School of Medicine, Albuquerque, and Daniel Stulberg, MD, FAAFP, Professor and Chair, Department of Family and Community Medicine, Western Michigan University Homer Stryker, MD School of Medicine, Kalamazoo.
1. Cardenas-de la Garza JA, De la Cruz-Valadez E, Ocampo-Candiani J, et al. Clinical spectrum of Lyme disease. Eur J Clin Microbiol Infect Dis. 2019;38:201-208. doi:10.1007/s10096-018-3417-1
1. Cardenas-de la Garza JA, De la Cruz-Valadez E, Ocampo-Candiani J, et al. Clinical spectrum of Lyme disease. Eur J Clin Microbiol Infect Dis. 2019;38:201-208. doi:10.1007/s10096-018-3417-1
Data Trends 2023: Access to Women's Health Care
- US Department of Veteran Affairs. Facts and statistics: women veterans in focus. Updated January 31, 2023. Accessed May 5, 2023. https://www.womenshealth.va.gov/materials-and-resources/facts-and-statistics.asp
- US Department of Defense. Department of Defense Releases Annual Demographics Report — Upward Trend in Number of Women Serving Continues. Published December 14, 2022. Accessed June 12, 2023. https://www.defense.gov/News/Releases/Release/Article/3246268/department-of-defense-releases-annual-demographics-report-upwardtrend-in-numbe/
- Meadows SO, Collins RL, Schuler MS, Beckman RL, Cefalu M. The Women’s Reproductive Health Survey (WRHS) of active-duty service members. RAND Corporation. Published 2022. Accessed May 5, 2023. https://www.rand.org/content/dam/rand/pubs/research_reports/RRA1000/RRA1031-1/RAND_RRA1031-1.pdf
- US Department of Veteran Affairs. Facts and statistics: women veterans in focus. Updated January 31, 2023. Accessed May 5, 2023. https://www.womenshealth.va.gov/materials-and-resources/facts-and-statistics.asp
- US Department of Defense. Department of Defense Releases Annual Demographics Report — Upward Trend in Number of Women Serving Continues. Published December 14, 2022. Accessed June 12, 2023. https://www.defense.gov/News/Releases/Release/Article/3246268/department-of-defense-releases-annual-demographics-report-upwardtrend-in-numbe/
- Meadows SO, Collins RL, Schuler MS, Beckman RL, Cefalu M. The Women’s Reproductive Health Survey (WRHS) of active-duty service members. RAND Corporation. Published 2022. Accessed May 5, 2023. https://www.rand.org/content/dam/rand/pubs/research_reports/RRA1000/RRA1031-1/RAND_RRA1031-1.pdf
- US Department of Veteran Affairs. Facts and statistics: women veterans in focus. Updated January 31, 2023. Accessed May 5, 2023. https://www.womenshealth.va.gov/materials-and-resources/facts-and-statistics.asp
- US Department of Defense. Department of Defense Releases Annual Demographics Report — Upward Trend in Number of Women Serving Continues. Published December 14, 2022. Accessed June 12, 2023. https://www.defense.gov/News/Releases/Release/Article/3246268/department-of-defense-releases-annual-demographics-report-upwardtrend-in-numbe/
- Meadows SO, Collins RL, Schuler MS, Beckman RL, Cefalu M. The Women’s Reproductive Health Survey (WRHS) of active-duty service members. RAND Corporation. Published 2022. Accessed May 5, 2023. https://www.rand.org/content/dam/rand/pubs/research_reports/RRA1000/RRA1031-1/RAND_RRA1031-1.pdf
Data Trends 2023: Rheumatoid Arthritis
- Morse JL et al. J Psychiatr Res. 2023;159:224-229. doi:10.1016/j.jpsychires.2023.01.039
- van Vollenhoven RF. BMC Med. 2009;7:12. doi:10.1186/1741-7015-7-12
- US Department of Veteran Affairs, National Center for Veteran Analysis and Statistics. Profile of veterans: 2017. Published March 2019. Accessed April 27, 2023. https://www.va.gov/vetdata/docs/SpecialReports/Profile_of_Veterans_2017.pdf
- Johnson TM et al. Arthritis Care Res (Hoboken). 2022 Nov 4. doi:10.1002/acr.25053
- Ebel AV et al. Arthritis Rheumatol. 2021;73(3):392-400. doi:10.1002/art.41559
- Sokolove J et al. Rheumatology (Oxford). 2016;55(11):1969-1977. doi:10.1093/rheumatology/kew285
- Alpizar-Rodriguez D et al. Rheumatology (Oxford). 2019;58(3):432-440. doi:10.1093/rheumatology/key311
- Chancay MG et al. Womens Midlife Health. 2019;5:3. doi:10.1186/s40695-019-0047-4
- Bongartz T et al. Arthritis Rheum. 2010;62(6):1583-1591. doi:10.1002/art.27405
- Kelly CA et al. Rheumatology (Oxford). 2014;53(9):1676-1682. doi:10.1093/rheumatology/keu165
- Koduri G et al. Rheumatology (Oxford). 2010;49(8):1483-1489. doi:10.1093/rheumatology/keq035
- Olson AL et al. Am J Respir Crit Care Med. 2011;183(3):372-378. doi:10.1164/rccm.201004-0622OC
- Mikuls TR et al. Rheumatology (Oxford). 2011;50(1):101-109. doi:10.1093/rheumatology/keq232
- England BR et al. Arthritis Care Res. 2016;68(1):36-45. doi:10.1002/acr.22642
- Morse JL et al. J Psychiatr Res. 2023;159:224-229. doi:10.1016/j.jpsychires.2023.01.039
- van Vollenhoven RF. BMC Med. 2009;7:12. doi:10.1186/1741-7015-7-12
- US Department of Veteran Affairs, National Center for Veteran Analysis and Statistics. Profile of veterans: 2017. Published March 2019. Accessed April 27, 2023. https://www.va.gov/vetdata/docs/SpecialReports/Profile_of_Veterans_2017.pdf
- Johnson TM et al. Arthritis Care Res (Hoboken). 2022 Nov 4. doi:10.1002/acr.25053
- Ebel AV et al. Arthritis Rheumatol. 2021;73(3):392-400. doi:10.1002/art.41559
- Sokolove J et al. Rheumatology (Oxford). 2016;55(11):1969-1977. doi:10.1093/rheumatology/kew285
- Alpizar-Rodriguez D et al. Rheumatology (Oxford). 2019;58(3):432-440. doi:10.1093/rheumatology/key311
- Chancay MG et al. Womens Midlife Health. 2019;5:3. doi:10.1186/s40695-019-0047-4
- Bongartz T et al. Arthritis Rheum. 2010;62(6):1583-1591. doi:10.1002/art.27405
- Kelly CA et al. Rheumatology (Oxford). 2014;53(9):1676-1682. doi:10.1093/rheumatology/keu165
- Koduri G et al. Rheumatology (Oxford). 2010;49(8):1483-1489. doi:10.1093/rheumatology/keq035
- Olson AL et al. Am J Respir Crit Care Med. 2011;183(3):372-378. doi:10.1164/rccm.201004-0622OC
- Mikuls TR et al. Rheumatology (Oxford). 2011;50(1):101-109. doi:10.1093/rheumatology/keq232
- England BR et al. Arthritis Care Res. 2016;68(1):36-45. doi:10.1002/acr.22642
- Morse JL et al. J Psychiatr Res. 2023;159:224-229. doi:10.1016/j.jpsychires.2023.01.039
- van Vollenhoven RF. BMC Med. 2009;7:12. doi:10.1186/1741-7015-7-12
- US Department of Veteran Affairs, National Center for Veteran Analysis and Statistics. Profile of veterans: 2017. Published March 2019. Accessed April 27, 2023. https://www.va.gov/vetdata/docs/SpecialReports/Profile_of_Veterans_2017.pdf
- Johnson TM et al. Arthritis Care Res (Hoboken). 2022 Nov 4. doi:10.1002/acr.25053
- Ebel AV et al. Arthritis Rheumatol. 2021;73(3):392-400. doi:10.1002/art.41559
- Sokolove J et al. Rheumatology (Oxford). 2016;55(11):1969-1977. doi:10.1093/rheumatology/kew285
- Alpizar-Rodriguez D et al. Rheumatology (Oxford). 2019;58(3):432-440. doi:10.1093/rheumatology/key311
- Chancay MG et al. Womens Midlife Health. 2019;5:3. doi:10.1186/s40695-019-0047-4
- Bongartz T et al. Arthritis Rheum. 2010;62(6):1583-1591. doi:10.1002/art.27405
- Kelly CA et al. Rheumatology (Oxford). 2014;53(9):1676-1682. doi:10.1093/rheumatology/keu165
- Koduri G et al. Rheumatology (Oxford). 2010;49(8):1483-1489. doi:10.1093/rheumatology/keq035
- Olson AL et al. Am J Respir Crit Care Med. 2011;183(3):372-378. doi:10.1164/rccm.201004-0622OC
- Mikuls TR et al. Rheumatology (Oxford). 2011;50(1):101-109. doi:10.1093/rheumatology/keq232
- England BR et al. Arthritis Care Res. 2016;68(1):36-45. doi:10.1002/acr.22642
Data Trends 2023: Migraine and Headache
22. Seng EK et al. Neurology. 2022;99(18):e1979-e1992. doi:10.1212/WNL.0000000000200888
23. Coffman C et al. Neurology. 2022;99(2):e187-e198. doi:10.1212/WNL.0000000000200518
24. Hesselbrock RR et al. Aerosp Med Hum Perform. 2022;93(1):26-31. doi:10.3357/amhp.5980.2022
25. Kuruvilla DE et al. BMC Complement Med Ther. 2022;22(1):22. doi:10.1186/s12906-022-03511-6
22. Seng EK et al. Neurology. 2022;99(18):e1979-e1992. doi:10.1212/WNL.0000000000200888
23. Coffman C et al. Neurology. 2022;99(2):e187-e198. doi:10.1212/WNL.0000000000200518
24. Hesselbrock RR et al. Aerosp Med Hum Perform. 2022;93(1):26-31. doi:10.3357/amhp.5980.2022
25. Kuruvilla DE et al. BMC Complement Med Ther. 2022;22(1):22. doi:10.1186/s12906-022-03511-6
22. Seng EK et al. Neurology. 2022;99(18):e1979-e1992. doi:10.1212/WNL.0000000000200888
23. Coffman C et al. Neurology. 2022;99(2):e187-e198. doi:10.1212/WNL.0000000000200518
24. Hesselbrock RR et al. Aerosp Med Hum Perform. 2022;93(1):26-31. doi:10.3357/amhp.5980.2022
25. Kuruvilla DE et al. BMC Complement Med Ther. 2022;22(1):22. doi:10.1186/s12906-022-03511-6
Data Trends 2023: Parkinson’s Disease
17. US Department of Veterans Affairs, Office of Research and Development.
Parkinson’s disease. Updated October 28, 2021. Accessed May 5, 2023.
https://www.research.va.gov/topics/parkinsons.cfm
18. Feeney M et al. Front Neurol. 2022;13:924999. doi:10.3389/fneur.2022.924999
19. Heronemus M et al. Parkinsonism Relat Disord. 2022;105:58-61. doi:10.1016/j.parkreldis.2022.11.003
20. Nejtek VA et al. PLoS One. 2021;16(11):e0258851. doi:10.1371/journal.pone.0258851
21. Yang Y et al. Dement Neurocogn Disord. 2016;15(3):75-81. doi:10.12779/dnd.2016.15.3.75
17. US Department of Veterans Affairs, Office of Research and Development.
Parkinson’s disease. Updated October 28, 2021. Accessed May 5, 2023.
https://www.research.va.gov/topics/parkinsons.cfm
18. Feeney M et al. Front Neurol. 2022;13:924999. doi:10.3389/fneur.2022.924999
19. Heronemus M et al. Parkinsonism Relat Disord. 2022;105:58-61. doi:10.1016/j.parkreldis.2022.11.003
20. Nejtek VA et al. PLoS One. 2021;16(11):e0258851. doi:10.1371/journal.pone.0258851
21. Yang Y et al. Dement Neurocogn Disord. 2016;15(3):75-81. doi:10.12779/dnd.2016.15.3.75
17. US Department of Veterans Affairs, Office of Research and Development.
Parkinson’s disease. Updated October 28, 2021. Accessed May 5, 2023.
https://www.research.va.gov/topics/parkinsons.cfm
18. Feeney M et al. Front Neurol. 2022;13:924999. doi:10.3389/fneur.2022.924999
19. Heronemus M et al. Parkinsonism Relat Disord. 2022;105:58-61. doi:10.1016/j.parkreldis.2022.11.003
20. Nejtek VA et al. PLoS One. 2021;16(11):e0258851. doi:10.1371/journal.pone.0258851
21. Yang Y et al. Dement Neurocogn Disord. 2016;15(3):75-81. doi:10.12779/dnd.2016.15.3.75
Data Trends 2023: Limb Loss and Prostheses
- US Department of Veterans Affairs. Amputation system of care [fact sheet]. Published December 2022. Accessed April 21, 2023. https://www.prosthetics.va.gov/factsheet/ASoC-FactSheet.pdf
- US Department of Veterans Affairs, Office of the Inspector General. Veteran Affairs Inspector General healthcare inspection: prosthetic limb care in VA facilities. Published March 8, 2012. Accessed April 21, 2023. https://www.va.gov/oig/pubs/VAOIG-11-02138-116.pdf
- Department of Veterans Affairs; Department of Defense. Clinical Practice Guideline for the Management of Upper Limb Amputation Rehabilitation. Patient Summary. Published March 2022. Accessed April 10, 2023. https://www.healthquality.va.gov/guidelines/Rehab/ULA/VADoDULACPG_PatientSummary_Final_508.pdf
- US Government Accountability Office, Report to Congressional Committees. Veterans Health Care: Agency efforts to provide and study prosthetics for small but growing female veteran population. Published November 2020. Accessed April 21, 2023. https://www.gao.gov/assets/gao-21-60.pdf
- 117th Congress. Access to Assistive Technology and Devices for Americans Study Act or the Triple A Study Act (H.R.2461). April 13, 2021. Accessed April 21, 2023. https://www.congress.gov/bill/117th-congress/housebill/2461
- Russell Esposito E, et al. Prosthet Orthot Int. 2023 Jan 2023. Online ahead of print. doi:10.1097/PXR.0000000000000192
- US Department of Veterans Affairs. Center for Limb Loss and MoBility. Updated January 27, 2022. Accessed April 21, 2023. https://www.amputation.research.va.gov/
- US Department of Veterans Affairs. Advanced Platform Technology Center. Accessed April 21, 2023. https://www.aptcenter.research.va.gov
- Sanchez-Bustamante C. Limb loss: DHA's three advanced rehab centers provide holistic care. Medicine and the Military. Published May 3, 2022. Accessed April 21, 2023. https://health.mil/News/Articles/2022/05/04/Limb-Loss-DHAs-Three-Advanced-Rehab-Centers-Provide-Holistic-Care
- Center for Neurorestoration and Neurotechnology. VA Providence Healthcare System. Accessed April 21, 2023. https://centerforneuro.org
- Webster JB. OPRA™ patient information sheet. US Department of Veteran Affairs, Rehabilitation and Prosthetic Services. Accessed April 21, 2023. https://www.rehab.va.gov/PROSTHETICS/asoc/resources/OPRA-PatientInformation.pdf
- Hoyt BW, et al. Expert Rev Med Devices. 2020;17(1):17-25. doi:10.1080/17434440.2020.1704623
- Ewing amputation in veterans with PAD undergoing BKA. ClinicalTrials.gov. Updated October 31, 2022. Accessed April 21, 2023. https://www.clinicaltrials.gov/ct2/show/NCT05437562
- US Department of Veterans Affairs. Amputation system of care [fact sheet]. Published December 2022. Accessed April 21, 2023. https://www.prosthetics.va.gov/factsheet/ASoC-FactSheet.pdf
- US Department of Veterans Affairs, Office of the Inspector General. Veteran Affairs Inspector General healthcare inspection: prosthetic limb care in VA facilities. Published March 8, 2012. Accessed April 21, 2023. https://www.va.gov/oig/pubs/VAOIG-11-02138-116.pdf
- Department of Veterans Affairs; Department of Defense. Clinical Practice Guideline for the Management of Upper Limb Amputation Rehabilitation. Patient Summary. Published March 2022. Accessed April 10, 2023. https://www.healthquality.va.gov/guidelines/Rehab/ULA/VADoDULACPG_PatientSummary_Final_508.pdf
- US Government Accountability Office, Report to Congressional Committees. Veterans Health Care: Agency efforts to provide and study prosthetics for small but growing female veteran population. Published November 2020. Accessed April 21, 2023. https://www.gao.gov/assets/gao-21-60.pdf
- 117th Congress. Access to Assistive Technology and Devices for Americans Study Act or the Triple A Study Act (H.R.2461). April 13, 2021. Accessed April 21, 2023. https://www.congress.gov/bill/117th-congress/housebill/2461
- Russell Esposito E, et al. Prosthet Orthot Int. 2023 Jan 2023. Online ahead of print. doi:10.1097/PXR.0000000000000192
- US Department of Veterans Affairs. Center for Limb Loss and MoBility. Updated January 27, 2022. Accessed April 21, 2023. https://www.amputation.research.va.gov/
- US Department of Veterans Affairs. Advanced Platform Technology Center. Accessed April 21, 2023. https://www.aptcenter.research.va.gov
- Sanchez-Bustamante C. Limb loss: DHA's three advanced rehab centers provide holistic care. Medicine and the Military. Published May 3, 2022. Accessed April 21, 2023. https://health.mil/News/Articles/2022/05/04/Limb-Loss-DHAs-Three-Advanced-Rehab-Centers-Provide-Holistic-Care
- Center for Neurorestoration and Neurotechnology. VA Providence Healthcare System. Accessed April 21, 2023. https://centerforneuro.org
- Webster JB. OPRA™ patient information sheet. US Department of Veteran Affairs, Rehabilitation and Prosthetic Services. Accessed April 21, 2023. https://www.rehab.va.gov/PROSTHETICS/asoc/resources/OPRA-PatientInformation.pdf
- Hoyt BW, et al. Expert Rev Med Devices. 2020;17(1):17-25. doi:10.1080/17434440.2020.1704623
- Ewing amputation in veterans with PAD undergoing BKA. ClinicalTrials.gov. Updated October 31, 2022. Accessed April 21, 2023. https://www.clinicaltrials.gov/ct2/show/NCT05437562
- US Department of Veterans Affairs. Amputation system of care [fact sheet]. Published December 2022. Accessed April 21, 2023. https://www.prosthetics.va.gov/factsheet/ASoC-FactSheet.pdf
- US Department of Veterans Affairs, Office of the Inspector General. Veteran Affairs Inspector General healthcare inspection: prosthetic limb care in VA facilities. Published March 8, 2012. Accessed April 21, 2023. https://www.va.gov/oig/pubs/VAOIG-11-02138-116.pdf
- Department of Veterans Affairs; Department of Defense. Clinical Practice Guideline for the Management of Upper Limb Amputation Rehabilitation. Patient Summary. Published March 2022. Accessed April 10, 2023. https://www.healthquality.va.gov/guidelines/Rehab/ULA/VADoDULACPG_PatientSummary_Final_508.pdf
- US Government Accountability Office, Report to Congressional Committees. Veterans Health Care: Agency efforts to provide and study prosthetics for small but growing female veteran population. Published November 2020. Accessed April 21, 2023. https://www.gao.gov/assets/gao-21-60.pdf
- 117th Congress. Access to Assistive Technology and Devices for Americans Study Act or the Triple A Study Act (H.R.2461). April 13, 2021. Accessed April 21, 2023. https://www.congress.gov/bill/117th-congress/housebill/2461
- Russell Esposito E, et al. Prosthet Orthot Int. 2023 Jan 2023. Online ahead of print. doi:10.1097/PXR.0000000000000192
- US Department of Veterans Affairs. Center for Limb Loss and MoBility. Updated January 27, 2022. Accessed April 21, 2023. https://www.amputation.research.va.gov/
- US Department of Veterans Affairs. Advanced Platform Technology Center. Accessed April 21, 2023. https://www.aptcenter.research.va.gov
- Sanchez-Bustamante C. Limb loss: DHA's three advanced rehab centers provide holistic care. Medicine and the Military. Published May 3, 2022. Accessed April 21, 2023. https://health.mil/News/Articles/2022/05/04/Limb-Loss-DHAs-Three-Advanced-Rehab-Centers-Provide-Holistic-Care
- Center for Neurorestoration and Neurotechnology. VA Providence Healthcare System. Accessed April 21, 2023. https://centerforneuro.org
- Webster JB. OPRA™ patient information sheet. US Department of Veteran Affairs, Rehabilitation and Prosthetic Services. Accessed April 21, 2023. https://www.rehab.va.gov/PROSTHETICS/asoc/resources/OPRA-PatientInformation.pdf
- Hoyt BW, et al. Expert Rev Med Devices. 2020;17(1):17-25. doi:10.1080/17434440.2020.1704623
- Ewing amputation in veterans with PAD undergoing BKA. ClinicalTrials.gov. Updated October 31, 2022. Accessed April 21, 2023. https://www.clinicaltrials.gov/ct2/show/NCT05437562
Data Trends 2023: Amyotrophic Lateral Sclerosis (ALS)
12. The ALS Association. ALS in the military. https://www.als.org/navigating-als/military-veterans/ALS-in-the-Military
13. McKay KA et al. Acta Neurol Scand. 2021;143(1):39-50. doi:10.1111/ane.13345
14. Lund EM et al. Muscle Nerve. 2021;63(6):807-811. doi:10.1002/mus.27181
15. Galea MD et al. Muscle Nerve. 2021;64(4):E18-E20. doi:10.1002/mus.27373
16. Re DB et al. J Neurol. 2022;269(5):2359-2377. doi:10.1007/s00415-021-10928-5
12. The ALS Association. ALS in the military. https://www.als.org/navigating-als/military-veterans/ALS-in-the-Military
13. McKay KA et al. Acta Neurol Scand. 2021;143(1):39-50. doi:10.1111/ane.13345
14. Lund EM et al. Muscle Nerve. 2021;63(6):807-811. doi:10.1002/mus.27181
15. Galea MD et al. Muscle Nerve. 2021;64(4):E18-E20. doi:10.1002/mus.27373
16. Re DB et al. J Neurol. 2022;269(5):2359-2377. doi:10.1007/s00415-021-10928-5
12. The ALS Association. ALS in the military. https://www.als.org/navigating-als/military-veterans/ALS-in-the-Military
13. McKay KA et al. Acta Neurol Scand. 2021;143(1):39-50. doi:10.1111/ane.13345
14. Lund EM et al. Muscle Nerve. 2021;63(6):807-811. doi:10.1002/mus.27181
15. Galea MD et al. Muscle Nerve. 2021;64(4):E18-E20. doi:10.1002/mus.27373
16. Re DB et al. J Neurol. 2022;269(5):2359-2377. doi:10.1007/s00415-021-10928-5
Data Trends 2023: Alzheimer’s and Dementia
6. Zhu CW, Sano M. Front Psychiatry. 2021;12:610334. doi:10.3389/fpsyt.2021.610334
7. Nianogo RA et al. JAMA Neurol. 2022;79(6):584-591. doi:10.1001/jamaneurol.2022.0976
8. Logue MW et al. Alzheimers Dement. 2022 Dec 22. Online ahead of print. doi:10.1002/alz.12870
9. Kempuraj D et al. Clin Ther. 2020;42(6):974-982. doi:10.1016/j.clinthera.2020.02.018
10. Martinez S et al. JAMA Neurol. 2021;78(4):473-477. doi:10.1001/jamaneurol.2020.5011
11. Verger A et al. Eur J Nucl Med Mol Imaging. 2023;50(6):1553-1555. doi:10.1007/s00259-023-06177-5
6. Zhu CW, Sano M. Front Psychiatry. 2021;12:610334. doi:10.3389/fpsyt.2021.610334
7. Nianogo RA et al. JAMA Neurol. 2022;79(6):584-591. doi:10.1001/jamaneurol.2022.0976
8. Logue MW et al. Alzheimers Dement. 2022 Dec 22. Online ahead of print. doi:10.1002/alz.12870
9. Kempuraj D et al. Clin Ther. 2020;42(6):974-982. doi:10.1016/j.clinthera.2020.02.018
10. Martinez S et al. JAMA Neurol. 2021;78(4):473-477. doi:10.1001/jamaneurol.2020.5011
11. Verger A et al. Eur J Nucl Med Mol Imaging. 2023;50(6):1553-1555. doi:10.1007/s00259-023-06177-5
6. Zhu CW, Sano M. Front Psychiatry. 2021;12:610334. doi:10.3389/fpsyt.2021.610334
7. Nianogo RA et al. JAMA Neurol. 2022;79(6):584-591. doi:10.1001/jamaneurol.2022.0976
8. Logue MW et al. Alzheimers Dement. 2022 Dec 22. Online ahead of print. doi:10.1002/alz.12870
9. Kempuraj D et al. Clin Ther. 2020;42(6):974-982. doi:10.1016/j.clinthera.2020.02.018
10. Martinez S et al. JAMA Neurol. 2021;78(4):473-477. doi:10.1001/jamaneurol.2020.5011
11. Verger A et al. Eur J Nucl Med Mol Imaging. 2023;50(6):1553-1555. doi:10.1007/s00259-023-06177-5
