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Which cytology results predict cervical intraepithelial neoplasia?
PRACTICE RECOMMENDATIONS

For women with cervical cytology results showing atypical squamous cell of undetermined significance (ASCUS) and positive results on DNA testing of a cervical sample for human papillomavirus (HPV) high-risk types, about 1 out of 8 progress to cervical intraepithelial neoplasia (CIN) grades 2 or 3 within 2 years of initial colposcopy results showing not more than CIN 1. Since women with cytology results of lowgrade squamous intraepithelial lesion (LSIL) progress to CIN 2 or 3 in the same proportion, management protocols for HPV-positive ASCUS and LSIL should be identical.

 
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Cox JT, Schiffman M, Solomon D. Prospective follow-up suggests similar risk of subsequent cervical intraepithelial neoplasia grade 1 or negative colposcopy and directed biopsy. Am J Obstet Gynecol 2003; 188:1406–1412.

Linda French, MD
Department of Family Practice, College of Human Medicine, Michigan State University, East Lansing. E-mail: [email protected].

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The Journal of Family Practice - 52(11)
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828-848
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Cox JT, Schiffman M, Solomon D. Prospective follow-up suggests similar risk of subsequent cervical intraepithelial neoplasia grade 1 or negative colposcopy and directed biopsy. Am J Obstet Gynecol 2003; 188:1406–1412.

Linda French, MD
Department of Family Practice, College of Human Medicine, Michigan State University, East Lansing. E-mail: [email protected].

Author and Disclosure Information

Cox JT, Schiffman M, Solomon D. Prospective follow-up suggests similar risk of subsequent cervical intraepithelial neoplasia grade 1 or negative colposcopy and directed biopsy. Am J Obstet Gynecol 2003; 188:1406–1412.

Linda French, MD
Department of Family Practice, College of Human Medicine, Michigan State University, East Lansing. E-mail: [email protected].

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PRACTICE RECOMMENDATIONS

For women with cervical cytology results showing atypical squamous cell of undetermined significance (ASCUS) and positive results on DNA testing of a cervical sample for human papillomavirus (HPV) high-risk types, about 1 out of 8 progress to cervical intraepithelial neoplasia (CIN) grades 2 or 3 within 2 years of initial colposcopy results showing not more than CIN 1. Since women with cytology results of lowgrade squamous intraepithelial lesion (LSIL) progress to CIN 2 or 3 in the same proportion, management protocols for HPV-positive ASCUS and LSIL should be identical.

 
PRACTICE RECOMMENDATIONS

For women with cervical cytology results showing atypical squamous cell of undetermined significance (ASCUS) and positive results on DNA testing of a cervical sample for human papillomavirus (HPV) high-risk types, about 1 out of 8 progress to cervical intraepithelial neoplasia (CIN) grades 2 or 3 within 2 years of initial colposcopy results showing not more than CIN 1. Since women with cytology results of lowgrade squamous intraepithelial lesion (LSIL) progress to CIN 2 or 3 in the same proportion, management protocols for HPV-positive ASCUS and LSIL should be identical.

 
Issue
The Journal of Family Practice - 52(11)
Issue
The Journal of Family Practice - 52(11)
Page Number
828-848
Page Number
828-848
Publications
Publications
Topics
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Which cytology results predict cervical intraepithelial neoplasia?
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Which cytology results predict cervical intraepithelial neoplasia?
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