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Key clinical point: Somatization and celiac disease are the primary risk factors associated with irritable bowel syndrome (IBS) in both men and women.
Major finding: The risk for IBS was almost 4-fold higher in men (adjusted odds ratio [aOR] 4.786; 95% CI 4.544-5.041) and women (aOR 5.326; 95% CI 4.863-5.832) experiencing somatization, with the second important influencing factor being celiac disease (men: aOR 4.107; 95% CI 3.132-5.385; women: aOR 3.783; 95% CI 3.310-4.323).
Study details: This study included 31,918 participants who met the Rome III criteria for IBS and completed the Digestive Health Questionnaire.
Disclosures: This study was supported by QW of the National Natural Science Foundation of China and the National Office for Philosophy and Social Sciences. The authors declared no potential conflicts of interest.
Source: Wang K et al. Factors related to irritable bowel syndrome and differences among subtypes: A cross-sectional study in the UK Biobank. Front Pharmacol. 2022;13:905564 (Aug 26). Doi: 10.3389/fphar.2022.905564
Key clinical point: Somatization and celiac disease are the primary risk factors associated with irritable bowel syndrome (IBS) in both men and women.
Major finding: The risk for IBS was almost 4-fold higher in men (adjusted odds ratio [aOR] 4.786; 95% CI 4.544-5.041) and women (aOR 5.326; 95% CI 4.863-5.832) experiencing somatization, with the second important influencing factor being celiac disease (men: aOR 4.107; 95% CI 3.132-5.385; women: aOR 3.783; 95% CI 3.310-4.323).
Study details: This study included 31,918 participants who met the Rome III criteria for IBS and completed the Digestive Health Questionnaire.
Disclosures: This study was supported by QW of the National Natural Science Foundation of China and the National Office for Philosophy and Social Sciences. The authors declared no potential conflicts of interest.
Source: Wang K et al. Factors related to irritable bowel syndrome and differences among subtypes: A cross-sectional study in the UK Biobank. Front Pharmacol. 2022;13:905564 (Aug 26). Doi: 10.3389/fphar.2022.905564
Key clinical point: Somatization and celiac disease are the primary risk factors associated with irritable bowel syndrome (IBS) in both men and women.
Major finding: The risk for IBS was almost 4-fold higher in men (adjusted odds ratio [aOR] 4.786; 95% CI 4.544-5.041) and women (aOR 5.326; 95% CI 4.863-5.832) experiencing somatization, with the second important influencing factor being celiac disease (men: aOR 4.107; 95% CI 3.132-5.385; women: aOR 3.783; 95% CI 3.310-4.323).
Study details: This study included 31,918 participants who met the Rome III criteria for IBS and completed the Digestive Health Questionnaire.
Disclosures: This study was supported by QW of the National Natural Science Foundation of China and the National Office for Philosophy and Social Sciences. The authors declared no potential conflicts of interest.
Source: Wang K et al. Factors related to irritable bowel syndrome and differences among subtypes: A cross-sectional study in the UK Biobank. Front Pharmacol. 2022;13:905564 (Aug 26). Doi: 10.3389/fphar.2022.905564