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WASHINGTON — Women with a history of preeclampsia have a twofold greater risk of developing subsequent type 2 diabetes—even in the absence of gestational diabetes—than do women without a history of the complication, said Dr. Darcy B. Carr in a report on a retrospective cohort study at the annual scientific sessions of the American Diabetes Association.
Dr. Carr, of the division of maternal-fetal medicine at the University of Washington, Seattle, and her colleagues looked at more than 25,000 women who delivered at the GHC between 1985 and 2002 after having been enrolled in the consumer-owned nonprofit health care system for at least a year. They followed the women, each of whom remained in GHC, for a mean of 8 years.
The women did not have known diabetes before pregnancy or subsequent type 1 diabetes. Subsequent type 2 diabetes was determined through 2005 based on inpatient and outpatient ICD-9 codes, pharmacy data, or lab data showing two elevated plasma glucose levels.
The two groups—about 2,100 women with preeclampsia and almost 25,000 without—had a similar mean age at the time of delivery, but those women who had preeclampsia were more likely to be multiparous and have gestational diabetes or preexisting chronic hypertension.
Subsequent type 2 diabetes was significantly more common in women who had preeclampsia (1.9% vs. 0.96%). A similar twofold increased risk remained after adjustment for age, multiparity, gestational diabetes, and chronic hypertension—and after women with gestational diabetes were excluded from the analysis, said Dr. Carr.
ELSEVIER GLOBAL MEDICAL NEWS
WASHINGTON — Women with a history of preeclampsia have a twofold greater risk of developing subsequent type 2 diabetes—even in the absence of gestational diabetes—than do women without a history of the complication, said Dr. Darcy B. Carr in a report on a retrospective cohort study at the annual scientific sessions of the American Diabetes Association.
Dr. Carr, of the division of maternal-fetal medicine at the University of Washington, Seattle, and her colleagues looked at more than 25,000 women who delivered at the GHC between 1985 and 2002 after having been enrolled in the consumer-owned nonprofit health care system for at least a year. They followed the women, each of whom remained in GHC, for a mean of 8 years.
The women did not have known diabetes before pregnancy or subsequent type 1 diabetes. Subsequent type 2 diabetes was determined through 2005 based on inpatient and outpatient ICD-9 codes, pharmacy data, or lab data showing two elevated plasma glucose levels.
The two groups—about 2,100 women with preeclampsia and almost 25,000 without—had a similar mean age at the time of delivery, but those women who had preeclampsia were more likely to be multiparous and have gestational diabetes or preexisting chronic hypertension.
Subsequent type 2 diabetes was significantly more common in women who had preeclampsia (1.9% vs. 0.96%). A similar twofold increased risk remained after adjustment for age, multiparity, gestational diabetes, and chronic hypertension—and after women with gestational diabetes were excluded from the analysis, said Dr. Carr.
ELSEVIER GLOBAL MEDICAL NEWS
WASHINGTON — Women with a history of preeclampsia have a twofold greater risk of developing subsequent type 2 diabetes—even in the absence of gestational diabetes—than do women without a history of the complication, said Dr. Darcy B. Carr in a report on a retrospective cohort study at the annual scientific sessions of the American Diabetes Association.
Dr. Carr, of the division of maternal-fetal medicine at the University of Washington, Seattle, and her colleagues looked at more than 25,000 women who delivered at the GHC between 1985 and 2002 after having been enrolled in the consumer-owned nonprofit health care system for at least a year. They followed the women, each of whom remained in GHC, for a mean of 8 years.
The women did not have known diabetes before pregnancy or subsequent type 1 diabetes. Subsequent type 2 diabetes was determined through 2005 based on inpatient and outpatient ICD-9 codes, pharmacy data, or lab data showing two elevated plasma glucose levels.
The two groups—about 2,100 women with preeclampsia and almost 25,000 without—had a similar mean age at the time of delivery, but those women who had preeclampsia were more likely to be multiparous and have gestational diabetes or preexisting chronic hypertension.
Subsequent type 2 diabetes was significantly more common in women who had preeclampsia (1.9% vs. 0.96%). A similar twofold increased risk remained after adjustment for age, multiparity, gestational diabetes, and chronic hypertension—and after women with gestational diabetes were excluded from the analysis, said Dr. Carr.
ELSEVIER GLOBAL MEDICAL NEWS