Article Type
Changed
Wed, 12/14/2016 - 10:29
Display Headline
Pancreatectomy Complication Rate Not Higher With Diabetes

CHICAGO — Patients with diabetes mellitus who undergo resection for pancreatic cancer do not have significantly increased risk for delayed gastric emptying, symptomatic fistulae formation, or extended length of hospital stay, compared with nondiabetic patients, data from a retrospective study suggest.

“We are all concerned that diabetics will have more gastric emptying issues, and we might be more likely to put a J [jejunostomy] tube into that patient. Our data suggest rates [of delayed emptying] are not significantly higher,” said Dr. David A. Kooby of the division of surgical oncology, Emory University, Atlanta.

Dr. Kooby was a coauthor of research presented by Dr. Carrie K. Chu at the annual clinical congress of the American College of Surgeons.

To compare 60-day complication rates, they and their associates reviewed the records of 251 patients with pancreatic ductal adenocarcinoma who underwent resection in 2000–2008. Of this group, 116 patients (46%) had preoperative diabetes.

The patients with diabetes were more likely to have at least one comorbidity than were those without diabetes, Dr. Chu said.

The type of pancreatectomy did not differ significantly between groups, nor did hospital length of stay (13–14 days). Most patients underwent pancreaticoduodenectomy. Just 1% of nondiabetic patients had total pancreatectomy, while none of the diabetes patients did. The remainder underwent left pancreatectomy.

There were no dramatic differences in complications by organ system, except for renal dysfunction. A total of 23% of 116 patients with diabetes versus 13% of 135 nondiabetic patients experienced renal dysfunction, “but it was mostly a mild elevation of creatinine,” said Dr. Chu, a surgical resident at Emory.

The 30-day mortality rates were 2.2% in the diabetes mellitus group and 1.7% in the nondiabetic patients, a difference that was not statistically significant, Dr. Chu said.

“The key point is that there was no major difference between diabetics and nondiabetics,” Dr. Kooby said.

Article PDF
Author and Disclosure Information

Topics
Author and Disclosure Information

Author and Disclosure Information

Article PDF
Article PDF

CHICAGO — Patients with diabetes mellitus who undergo resection for pancreatic cancer do not have significantly increased risk for delayed gastric emptying, symptomatic fistulae formation, or extended length of hospital stay, compared with nondiabetic patients, data from a retrospective study suggest.

“We are all concerned that diabetics will have more gastric emptying issues, and we might be more likely to put a J [jejunostomy] tube into that patient. Our data suggest rates [of delayed emptying] are not significantly higher,” said Dr. David A. Kooby of the division of surgical oncology, Emory University, Atlanta.

Dr. Kooby was a coauthor of research presented by Dr. Carrie K. Chu at the annual clinical congress of the American College of Surgeons.

To compare 60-day complication rates, they and their associates reviewed the records of 251 patients with pancreatic ductal adenocarcinoma who underwent resection in 2000–2008. Of this group, 116 patients (46%) had preoperative diabetes.

The patients with diabetes were more likely to have at least one comorbidity than were those without diabetes, Dr. Chu said.

The type of pancreatectomy did not differ significantly between groups, nor did hospital length of stay (13–14 days). Most patients underwent pancreaticoduodenectomy. Just 1% of nondiabetic patients had total pancreatectomy, while none of the diabetes patients did. The remainder underwent left pancreatectomy.

There were no dramatic differences in complications by organ system, except for renal dysfunction. A total of 23% of 116 patients with diabetes versus 13% of 135 nondiabetic patients experienced renal dysfunction, “but it was mostly a mild elevation of creatinine,” said Dr. Chu, a surgical resident at Emory.

The 30-day mortality rates were 2.2% in the diabetes mellitus group and 1.7% in the nondiabetic patients, a difference that was not statistically significant, Dr. Chu said.

“The key point is that there was no major difference between diabetics and nondiabetics,” Dr. Kooby said.

CHICAGO — Patients with diabetes mellitus who undergo resection for pancreatic cancer do not have significantly increased risk for delayed gastric emptying, symptomatic fistulae formation, or extended length of hospital stay, compared with nondiabetic patients, data from a retrospective study suggest.

“We are all concerned that diabetics will have more gastric emptying issues, and we might be more likely to put a J [jejunostomy] tube into that patient. Our data suggest rates [of delayed emptying] are not significantly higher,” said Dr. David A. Kooby of the division of surgical oncology, Emory University, Atlanta.

Dr. Kooby was a coauthor of research presented by Dr. Carrie K. Chu at the annual clinical congress of the American College of Surgeons.

To compare 60-day complication rates, they and their associates reviewed the records of 251 patients with pancreatic ductal adenocarcinoma who underwent resection in 2000–2008. Of this group, 116 patients (46%) had preoperative diabetes.

The patients with diabetes were more likely to have at least one comorbidity than were those without diabetes, Dr. Chu said.

The type of pancreatectomy did not differ significantly between groups, nor did hospital length of stay (13–14 days). Most patients underwent pancreaticoduodenectomy. Just 1% of nondiabetic patients had total pancreatectomy, while none of the diabetes patients did. The remainder underwent left pancreatectomy.

There were no dramatic differences in complications by organ system, except for renal dysfunction. A total of 23% of 116 patients with diabetes versus 13% of 135 nondiabetic patients experienced renal dysfunction, “but it was mostly a mild elevation of creatinine,” said Dr. Chu, a surgical resident at Emory.

The 30-day mortality rates were 2.2% in the diabetes mellitus group and 1.7% in the nondiabetic patients, a difference that was not statistically significant, Dr. Chu said.

“The key point is that there was no major difference between diabetics and nondiabetics,” Dr. Kooby said.

Topics
Article Type
Display Headline
Pancreatectomy Complication Rate Not Higher With Diabetes
Display Headline
Pancreatectomy Complication Rate Not Higher With Diabetes
Article Source

PURLs Copyright

Inside the Article

Article PDF Media