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Key clinical point: The CoxNet machine learning model was validated as a predictor of recurrence of HCC in patients who underwent liver transplant.

Major finding: The concordance score of the CoxNet-based recurrence prediction model was 0.75, which significantly outperformed the alpha-fetoprotein score (0.64; P = 0.04) and MORAL score (0.64; P = 0.03).

Study details: The data come from 739 adults with hepatocellular carcinoma who underwent liver transplants between 2000 and 2016.

Disclosures: The study received no outside funding. The researchers had no financial conflicts to disclose.

Source: Ivanics T et al. Liver Transpl. 2021 Oct 9. doi: 10.1002/lt.26332. 

 

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Key clinical point: The CoxNet machine learning model was validated as a predictor of recurrence of HCC in patients who underwent liver transplant.

Major finding: The concordance score of the CoxNet-based recurrence prediction model was 0.75, which significantly outperformed the alpha-fetoprotein score (0.64; P = 0.04) and MORAL score (0.64; P = 0.03).

Study details: The data come from 739 adults with hepatocellular carcinoma who underwent liver transplants between 2000 and 2016.

Disclosures: The study received no outside funding. The researchers had no financial conflicts to disclose.

Source: Ivanics T et al. Liver Transpl. 2021 Oct 9. doi: 10.1002/lt.26332. 

 

Key clinical point: The CoxNet machine learning model was validated as a predictor of recurrence of HCC in patients who underwent liver transplant.

Major finding: The concordance score of the CoxNet-based recurrence prediction model was 0.75, which significantly outperformed the alpha-fetoprotein score (0.64; P = 0.04) and MORAL score (0.64; P = 0.03).

Study details: The data come from 739 adults with hepatocellular carcinoma who underwent liver transplants between 2000 and 2016.

Disclosures: The study received no outside funding. The researchers had no financial conflicts to disclose.

Source: Ivanics T et al. Liver Transpl. 2021 Oct 9. doi: 10.1002/lt.26332. 

 

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Clinical Edge Journal Scan: HCC November 2021
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