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Key clinical point: Signs of systemic inflammation were significantly lower among white male prostate cancer patients compared to matched controls, but no difference in these measures was observed between cases and controls among black men.

Major finding: Among black men, trajectories in neutrophil-to-lymphocyte ratio (NLR) and monocyte-to-lymphocyte ratio (MLR) were similar between prostate cancer patients and controls. Among white men, both NLR and MLR values were higher among controls compared to prostate cancer patients.

Study details: The data come from 10 478 men with benign prostate cancer who were followed for up to 18 years; researchers created a nested case-control study of 822 pairs.

Disclosures: The study was supported by the National Institute of Environmental Health Sciences. The researchers had no financial conflicts to disclose.

Source: Rundle AG et al. PLoS One. 2021 Jul 9. doi: 10.1371/journal.pone.0252951.

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Key clinical point: Signs of systemic inflammation were significantly lower among white male prostate cancer patients compared to matched controls, but no difference in these measures was observed between cases and controls among black men.

Major finding: Among black men, trajectories in neutrophil-to-lymphocyte ratio (NLR) and monocyte-to-lymphocyte ratio (MLR) were similar between prostate cancer patients and controls. Among white men, both NLR and MLR values were higher among controls compared to prostate cancer patients.

Study details: The data come from 10 478 men with benign prostate cancer who were followed for up to 18 years; researchers created a nested case-control study of 822 pairs.

Disclosures: The study was supported by the National Institute of Environmental Health Sciences. The researchers had no financial conflicts to disclose.

Source: Rundle AG et al. PLoS One. 2021 Jul 9. doi: 10.1371/journal.pone.0252951.

Key clinical point: Signs of systemic inflammation were significantly lower among white male prostate cancer patients compared to matched controls, but no difference in these measures was observed between cases and controls among black men.

Major finding: Among black men, trajectories in neutrophil-to-lymphocyte ratio (NLR) and monocyte-to-lymphocyte ratio (MLR) were similar between prostate cancer patients and controls. Among white men, both NLR and MLR values were higher among controls compared to prostate cancer patients.

Study details: The data come from 10 478 men with benign prostate cancer who were followed for up to 18 years; researchers created a nested case-control study of 822 pairs.

Disclosures: The study was supported by the National Institute of Environmental Health Sciences. The researchers had no financial conflicts to disclose.

Source: Rundle AG et al. PLoS One. 2021 Jul 9. doi: 10.1371/journal.pone.0252951.

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Clinical Edge Journal Scan: Prostate Cancer August 2021
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