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SANTA MONICA, CALIF. — It may not be necessary to refer women for colposcopy after a single, mildly dyskaryotic cervical smear, according to a poster presentation by A.S. Ahmed at the biennial meeting of the International Gynecologic Cancer Society.
In a retrospective analysis of 375 patients who had a single smear positive for mild dyskaryosis and were followed for 4 years, Mr. Ahmed of King's College, London, and his colleagues found that 50% of the follow-up smears were negative in the first year, and 87% stayed negative over the full 4 years. In all, 791 follow-up smears were performed and 477 (60%) were negative. After those negative smears, only 61 (13%) smears in 54 patients (14%) reverted to low-grade abnormalities. Of the 375 patients, 70 (19%) required an excisional biopsy. The prevalence of high-grade cervical intraepithelial neoplasia (CIN) was 11%, and no cases of cancer were detected.
The authors said a single mildly abnormal cervical smear need not trigger a referral to colposcopy.
SANTA MONICA, CALIF. — It may not be necessary to refer women for colposcopy after a single, mildly dyskaryotic cervical smear, according to a poster presentation by A.S. Ahmed at the biennial meeting of the International Gynecologic Cancer Society.
In a retrospective analysis of 375 patients who had a single smear positive for mild dyskaryosis and were followed for 4 years, Mr. Ahmed of King's College, London, and his colleagues found that 50% of the follow-up smears were negative in the first year, and 87% stayed negative over the full 4 years. In all, 791 follow-up smears were performed and 477 (60%) were negative. After those negative smears, only 61 (13%) smears in 54 patients (14%) reverted to low-grade abnormalities. Of the 375 patients, 70 (19%) required an excisional biopsy. The prevalence of high-grade cervical intraepithelial neoplasia (CIN) was 11%, and no cases of cancer were detected.
The authors said a single mildly abnormal cervical smear need not trigger a referral to colposcopy.
SANTA MONICA, CALIF. — It may not be necessary to refer women for colposcopy after a single, mildly dyskaryotic cervical smear, according to a poster presentation by A.S. Ahmed at the biennial meeting of the International Gynecologic Cancer Society.
In a retrospective analysis of 375 patients who had a single smear positive for mild dyskaryosis and were followed for 4 years, Mr. Ahmed of King's College, London, and his colleagues found that 50% of the follow-up smears were negative in the first year, and 87% stayed negative over the full 4 years. In all, 791 follow-up smears were performed and 477 (60%) were negative. After those negative smears, only 61 (13%) smears in 54 patients (14%) reverted to low-grade abnormalities. Of the 375 patients, 70 (19%) required an excisional biopsy. The prevalence of high-grade cervical intraepithelial neoplasia (CIN) was 11%, and no cases of cancer were detected.
The authors said a single mildly abnormal cervical smear need not trigger a referral to colposcopy.