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SVS is working with a prominent legal health firm to produce a series of “Hot Topic” articles and webinar to address specific challenges members face in their practices. The first article focuses on ways to expand existing practices to include an in-office vascular surgical suite or establish a free-standing ambulatory surgery center individually or in partnership with a hospital or complementary specialty group. The article highlights the legal, financial, and operational considerations as well as key questions to consider.
SVS is working with a prominent legal health firm to produce a series of “Hot Topic” articles and webinar to address specific challenges members face in their practices. The first article focuses on ways to expand existing practices to include an in-office vascular surgical suite or establish a free-standing ambulatory surgery center individually or in partnership with a hospital or complementary specialty group. The article highlights the legal, financial, and operational considerations as well as key questions to consider.
SVS is working with a prominent legal health firm to produce a series of “Hot Topic” articles and webinar to address specific challenges members face in their practices. The first article focuses on ways to expand existing practices to include an in-office vascular surgical suite or establish a free-standing ambulatory surgery center individually or in partnership with a hospital or complementary specialty group. The article highlights the legal, financial, and operational considerations as well as key questions to consider.
Bronchoscopy sedation changes in 2017
A major change in coding for bronchoscopy occurred on January 1, 2017, as moderate (conscious) sedation is now separately identified from the work relative value units (wRVUs) for the bronchoscopy codes. While traditionally the bronchoscopist provided moderate sedation, in recent clinical practice, other individuals often provide the sedation. CMS mandated refinement of separate Current Procedural Terminology (CPT®) codes to account for the work of moderate procedural sedation. In the final rule published in November 2016, CMS removed 0.25 wRVUs from many of the bronchoscopy codes to account for the work of moderate sedation. To be reimbursed appropriately, include a moderate sedation CPT code with all bronchoscopy procedures.
Use codes 99151 and 99155 for patients younger than 5 years. For a patient 5 years or older, when the bronchoscopist provides moderate sedation, report code 99152 for the initial 15 minutes and 99153 for subsequent time in 15-minute increments. For a patient 5 years or older, when a provider other than the bronchoscopist provides moderate sedation, use code 99156 for the initial 15 minutes and 99157 for subsequent time in 15-minute increments. Utilize codes 99156 and 99157 only when a second provider (other than the bronchoscopist) performs moderate sedation in the facility setting (eg, hospital, outpatient hospital/ambulatory surgery center, skilled nursing facility). When the second provider performs these services in the nonfacility setting (eg, physician office, freestanding imaging center), do not report codes 99155, 99156, or 99157. Moderate sedation does not include minimal sedation (anxiolysis), deep sedation, or monitored anesthesia care (00100-01999).
Do not use a moderate sedation code (99151-2 or 99155-6) if providing less than 10 minutes of moderate sedation. As with other time-based codes, use the subsequent codes 99153 and 99157 when moderate sedation lasts 8 minutes or longer than the initial 15 minutes. The time for moderate sedation begins with the administration of the sedating agent and concludes when the continuous face-to-face presence of the bronchoscopist ends after completion of the procedure. Intermittent, re-evaluation of the patient afterward is postservice work and is not included in the time for moderate sedation. For example, if the bronchoscopist provides moderate sedation for 25 minutes in a 65-year-old man, report 99152 (for the initial 15 minutes) and 99153 (for the subsequent 10 minutes). If an individual other than the bronchoscopist provides moderate sedation for 41 minutes in a 57-year-old woman, use 99156 (for the initial 15 minutes) and two units of 99157 (for the subsequent 26 minutes). If a bronchoscopist provides moderate sedation and reports the appropriate codes after January 1, the 0.25 wRVU change will have no financial impact compared with 2016. If a second provider performs the moderate sedation, expect an approximately $8.72 drop in reimbursement per procedure.
A major change in coding for bronchoscopy occurred on January 1, 2017, as moderate (conscious) sedation is now separately identified from the work relative value units (wRVUs) for the bronchoscopy codes. While traditionally the bronchoscopist provided moderate sedation, in recent clinical practice, other individuals often provide the sedation. CMS mandated refinement of separate Current Procedural Terminology (CPT®) codes to account for the work of moderate procedural sedation. In the final rule published in November 2016, CMS removed 0.25 wRVUs from many of the bronchoscopy codes to account for the work of moderate sedation. To be reimbursed appropriately, include a moderate sedation CPT code with all bronchoscopy procedures.
Use codes 99151 and 99155 for patients younger than 5 years. For a patient 5 years or older, when the bronchoscopist provides moderate sedation, report code 99152 for the initial 15 minutes and 99153 for subsequent time in 15-minute increments. For a patient 5 years or older, when a provider other than the bronchoscopist provides moderate sedation, use code 99156 for the initial 15 minutes and 99157 for subsequent time in 15-minute increments. Utilize codes 99156 and 99157 only when a second provider (other than the bronchoscopist) performs moderate sedation in the facility setting (eg, hospital, outpatient hospital/ambulatory surgery center, skilled nursing facility). When the second provider performs these services in the nonfacility setting (eg, physician office, freestanding imaging center), do not report codes 99155, 99156, or 99157. Moderate sedation does not include minimal sedation (anxiolysis), deep sedation, or monitored anesthesia care (00100-01999).
Do not use a moderate sedation code (99151-2 or 99155-6) if providing less than 10 minutes of moderate sedation. As with other time-based codes, use the subsequent codes 99153 and 99157 when moderate sedation lasts 8 minutes or longer than the initial 15 minutes. The time for moderate sedation begins with the administration of the sedating agent and concludes when the continuous face-to-face presence of the bronchoscopist ends after completion of the procedure. Intermittent, re-evaluation of the patient afterward is postservice work and is not included in the time for moderate sedation. For example, if the bronchoscopist provides moderate sedation for 25 minutes in a 65-year-old man, report 99152 (for the initial 15 minutes) and 99153 (for the subsequent 10 minutes). If an individual other than the bronchoscopist provides moderate sedation for 41 minutes in a 57-year-old woman, use 99156 (for the initial 15 minutes) and two units of 99157 (for the subsequent 26 minutes). If a bronchoscopist provides moderate sedation and reports the appropriate codes after January 1, the 0.25 wRVU change will have no financial impact compared with 2016. If a second provider performs the moderate sedation, expect an approximately $8.72 drop in reimbursement per procedure.
A major change in coding for bronchoscopy occurred on January 1, 2017, as moderate (conscious) sedation is now separately identified from the work relative value units (wRVUs) for the bronchoscopy codes. While traditionally the bronchoscopist provided moderate sedation, in recent clinical practice, other individuals often provide the sedation. CMS mandated refinement of separate Current Procedural Terminology (CPT®) codes to account for the work of moderate procedural sedation. In the final rule published in November 2016, CMS removed 0.25 wRVUs from many of the bronchoscopy codes to account for the work of moderate sedation. To be reimbursed appropriately, include a moderate sedation CPT code with all bronchoscopy procedures.
Use codes 99151 and 99155 for patients younger than 5 years. For a patient 5 years or older, when the bronchoscopist provides moderate sedation, report code 99152 for the initial 15 minutes and 99153 for subsequent time in 15-minute increments. For a patient 5 years or older, when a provider other than the bronchoscopist provides moderate sedation, use code 99156 for the initial 15 minutes and 99157 for subsequent time in 15-minute increments. Utilize codes 99156 and 99157 only when a second provider (other than the bronchoscopist) performs moderate sedation in the facility setting (eg, hospital, outpatient hospital/ambulatory surgery center, skilled nursing facility). When the second provider performs these services in the nonfacility setting (eg, physician office, freestanding imaging center), do not report codes 99155, 99156, or 99157. Moderate sedation does not include minimal sedation (anxiolysis), deep sedation, or monitored anesthesia care (00100-01999).
Do not use a moderate sedation code (99151-2 or 99155-6) if providing less than 10 minutes of moderate sedation. As with other time-based codes, use the subsequent codes 99153 and 99157 when moderate sedation lasts 8 minutes or longer than the initial 15 minutes. The time for moderate sedation begins with the administration of the sedating agent and concludes when the continuous face-to-face presence of the bronchoscopist ends after completion of the procedure. Intermittent, re-evaluation of the patient afterward is postservice work and is not included in the time for moderate sedation. For example, if the bronchoscopist provides moderate sedation for 25 minutes in a 65-year-old man, report 99152 (for the initial 15 minutes) and 99153 (for the subsequent 10 minutes). If an individual other than the bronchoscopist provides moderate sedation for 41 minutes in a 57-year-old woman, use 99156 (for the initial 15 minutes) and two units of 99157 (for the subsequent 26 minutes). If a bronchoscopist provides moderate sedation and reports the appropriate codes after January 1, the 0.25 wRVU change will have no financial impact compared with 2016. If a second provider performs the moderate sedation, expect an approximately $8.72 drop in reimbursement per procedure.
Sleep strategies: Sleep-disordered breathing and pregnancy complications: Emerging data and future directions
Background
Sleep-disordered breathing (SDB) conditions are characterized by abnormal respiratory patterns and abnormal gas exchange during sleep.1-3 Obstructive sleep apnea (OSA), the most common type of SDB, is characterized by repetitive episodes of airway narrowing during sleep that lead to respiratory disruption, hypoxia, and sleep fragmentation. In reproductive-aged women, epidemiologic studies suggest a 2% to 13% prevalence of OSA.4-6 Pregnancy is associated with changes that promote OSA, such as weight gain and edema of the upper airway.7 Frequent snoring, a common symptom of OSA, is endorsed by 15% to 25% of pregnant women.8-10 Health outcomes that have been linked to SDB in the nonpregnant population, such as hypertension and insulin-resistant diabetes, have clinically relevant correlates in pregnancy (preeclampsia, gestational diabetes).11-13
While several retrospective and cross-sectional studies suggest that SDB may increase the risk of developing hypertensive disorders and gestational diabetes during pregnancy,16-18 up until recently, there were limited and conflicting data from prospective observational cohorts in which SDB exposure and pregnancy outcomes have been methodically measured and confounding variables carefully considered.19-21 Louis et al.19 reported on a cohort of 175 obese women and demonstrated that women with SDB (apnea-hypopnea index greater than or equal to 5) were more likely to develop preeclampsia (adjusted odds ratio, 3.5; 95% CI, 1.3, 9.9). However, two other small studies failed to demonstrate a positive association between SDB and pregnancy-related hypertension, but one suggested a relationship between SDB and gestational diabetes.20,21
Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-Be Sleep-Disordered Breathing Substudy
The Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-Be Sleep-Disordered Breathing Substudy (nuMoM2b-SDB) was a prospective cohort study.22,23 Level 3 home sleep tests were performed using a six-channel monitor that was self-applied by the participant twice during pregnancy, first between 60 and 150 weeks of pregnancy and then again between 220 and 310 weeks. An apnea-hypopnea index (AHI) of at least 5 was used to define SDB. The study was powered to test the primary hypothesis that SDB occurring in pregnancy is associated with an increased incidence of preeclampsia. Secondary outcomes were rates of hypertensive disorders of pregnancy, defined as preeclampsia and prenatal gestational hypertension, and gestational diabetes. Crude and adjusted odds ratios and 95% confidence intervals were calculated from univariate and multivariate logistic regression models. Adjustment covariates included maternal age (less than or equal to 21, 22-35, and over 35 years), body mass index (less than 25, 25 to less than 30, greater than or equal to 30 kg/m2), chronic hypertension (yes, no), and, for midpregnancy, rate of weight gain per week between early and midpregnancy assessments, treated as a continuous variable.
Conclusions and future directions
The nuMoM2b data are provocative because sleep apnea is a potentially modifiable risk factor for adverse pregnancy outcomes. While a majority of SDB cases identified during pregnancy were mild, the nuMoM2b data demonstrate that even modest elevations of AHI in pregnancy are associated with an increased risk of developing hypertensive disorders and an increased incidence of gestational diabetes.
Pregnancy is conceivably an ideal scenario in which to better understand the role of SDB treatment as a preventive strategy for reducing cardiometabolic morbidity as the time frame needed to measure incident outcomes after initiating therapy is significantly contracted. However, data regarding the role of OSA treatment with continuous positive airway pressure (CPAP) during pregnancy, both regarding its acceptability to patients and its therapeutic benefit, are extremely limited. Further research is needed to establish whether universal screening for and treating of SDB in pregnancy can mitigate the risks and consequences of hypertensive disorders of pregnancy and gestational diabetes. However, in the meantime, we have to recognize that as our obstetric patient population is becoming more obese, we will encounter more women with symptomatic SDB in pregnancy. It is well documented that patients with symptomatic SDB, those who report that their snoring leads to chronic sleep disruption and excessive daytime sleepiness, can benefit from CPAP in terms of sleep quality and daytime function. Therefore, in addition to encouraging women already prescribed CPAP to continue their therapy during pregnancy, obstetricians who encounter a patient reporting severe SDB symptoms should refer her to a sleep specialist for further evaluation.
Dr. Facco is assistant professor, department of obstetrics and gynecology, University of Pittsburgh, Magee-Women’s Hospital, Magee Women’s Research Institute.
References
1. Berry RB, Budhiraja R, Gottlieb DJ, et al. Rules for scoring respiratory events in sleep: Update of the 2007 AASM Manual for the Scoring of Sleep and Associated Events. Deliberations of the Sleep Apnea Definitions Task Force of the American Academy of Sleep Medicine. J Clin Sleep Med. 2012;8(5):597-619.
2. Park JG, Ramar K, Olson EJ. Updates on definition, consequences, and management of obstructive sleep apnea. Mayo Clin Proc. 2011;86(6):549-54; quiz, 554-5.
3. Iber C, Ancoli-Israel S, Chesson A, Quan S. The AASM Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications. 1st ed. Westchester, Ill.: American Academy of Sleep Medicine, 2007.
4. Peppard PE, Young T, Barnet JH, Palta M, Hagen EW, Hla KM. Increased prevalence of sleep-disordered breathing in adults. Am J Epidemiol. 2013 May 1;177(9):1006-14.
5. Young T, Palta M, Dempsey J, Skatrud J, Weber S, Badr S. The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med. 1993;328(17):1230-5.
6. Young T, Finn L, Austin D, Peterson A. Menopausal status and sleep-disordered breathing in the Wisconsin Sleep Cohort Study. Am J Respir Crit Care Med. 2003;167(9):1181-5.
7. Pien GW, Schwab RJ. Sleep disorders during pregnancy. Sleep. 2004;27(7):1405-17.
8. Hedman C, Pohjasvaara T, Tolonen U, Suhonen-Malm AS, Myllyla VV. Effects of pregnancy on mothers’ sleep. Sleep Med. 2002;3(1):37-42.
9. Pien GW, Fife D, Pack AI, Nkwuo JE, Schwab RJ. Changes in symptoms of sleep-disordered breathing during pregnancy. Sleep. 2005;28(10):1299-1305.
10. Facco FL, Kramer J, Ho KH, Zee PC, Grobman WA. Sleep disturbances in pregnancy. Obstet Gynecol. 2010;115(1):77-83.
11. Peppard PE, Young T, Palta M, Skatrud J. Prospective study of the association between sleep-disordered breathing and hypertension. N Engl J Med. 2000;342(19):1378-84.
12. Punjabi NM, Shahar E, Redline S, et al. Sleep-disordered breathing, glucose intolerance, and insulin resistance: The Sleep Heart Health Study. Am J Epidemiol. 2004;160(6):521-30.
13. Reichmuth KJ, Austin D, Skatrud JB, Young T. Association of sleep apnea and type II diabetes: A population-based study. Am J Respir Crit Care Med. 2005;172(12):1590-5.
14. Dempsey JA, Veasey SC, Morgan BJ, O’Donnell CP. Pathophysiology of sleep apnea. Physiol Rev. 2010;90(1):47-112.
15. Romero R, Badr MS. A role for sleep disorders in pregnancy complications: Challenges and opportunities. Am J Obstet Gynecol. 2014;210(1):3-11.
16. O’Brien LM, Bullough AS, Owusu JT, et al. Pregnancy-onset habitual snoring, gestational hypertension, and preeclampsia: Prospective cohort study. Am J Obstet Gynecol. 2012;207(6):487.e1-9
17. Chen YH, Kang JH, Lin CC, Wang IT, Keller JJ, Lin HC. Obstructive sleep apnea and the risk of adverse pregnancy outcomes. Am J Obstet Gynecol. 2012;206(2):136.e1-5.
18. Bourjeily G, Raker CA, Chalhoub M, Miller MA, et al. Pregnancy and fetal outcomes of symptoms of sleep-disordered breathing. Eur Respir J. 2010;36(4):849-55.
19. Louis J, Auckley D, Miladinovic B, et al. Perinatal outcomes associated with obstructive sleep apnea in obese pregnant women. Obstet Gynecol. 2012;120:1085-92.
20. Facco FL, Ouyang DW, Zee PC, et al. Implications of sleep-disordered breathing in pregnancy. Am J Obstet Gynecol. 2014 Jun;210(6):559.e1-6.
21. Pien GW, Pack AI, Jackson N, Maislin G, Macones GA, Schwab RJ. Risk factors for sleep-disordered breathing in pregnancy. Thorax. 2014;69(4):371-7.
22. Facco FL, Parker CB, Reddy UM, et al. NuMoM2b Sleep-Disordered Breathing study: Objectives and methods. Am J Obstet Gynecol. 2015 April;212(4):542.e1–542.e127.
23. Facco FL, Parker CB, Reddy UM, et al. Association between sleep-disordered breathing and hypertensive disorders of pregn ancy and gestational diabetes mellitus. Obstet Gynecol. ePub. 2016 Dec 2.
Background
Sleep-disordered breathing (SDB) conditions are characterized by abnormal respiratory patterns and abnormal gas exchange during sleep.1-3 Obstructive sleep apnea (OSA), the most common type of SDB, is characterized by repetitive episodes of airway narrowing during sleep that lead to respiratory disruption, hypoxia, and sleep fragmentation. In reproductive-aged women, epidemiologic studies suggest a 2% to 13% prevalence of OSA.4-6 Pregnancy is associated with changes that promote OSA, such as weight gain and edema of the upper airway.7 Frequent snoring, a common symptom of OSA, is endorsed by 15% to 25% of pregnant women.8-10 Health outcomes that have been linked to SDB in the nonpregnant population, such as hypertension and insulin-resistant diabetes, have clinically relevant correlates in pregnancy (preeclampsia, gestational diabetes).11-13
While several retrospective and cross-sectional studies suggest that SDB may increase the risk of developing hypertensive disorders and gestational diabetes during pregnancy,16-18 up until recently, there were limited and conflicting data from prospective observational cohorts in which SDB exposure and pregnancy outcomes have been methodically measured and confounding variables carefully considered.19-21 Louis et al.19 reported on a cohort of 175 obese women and demonstrated that women with SDB (apnea-hypopnea index greater than or equal to 5) were more likely to develop preeclampsia (adjusted odds ratio, 3.5; 95% CI, 1.3, 9.9). However, two other small studies failed to demonstrate a positive association between SDB and pregnancy-related hypertension, but one suggested a relationship between SDB and gestational diabetes.20,21
Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-Be Sleep-Disordered Breathing Substudy
The Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-Be Sleep-Disordered Breathing Substudy (nuMoM2b-SDB) was a prospective cohort study.22,23 Level 3 home sleep tests were performed using a six-channel monitor that was self-applied by the participant twice during pregnancy, first between 60 and 150 weeks of pregnancy and then again between 220 and 310 weeks. An apnea-hypopnea index (AHI) of at least 5 was used to define SDB. The study was powered to test the primary hypothesis that SDB occurring in pregnancy is associated with an increased incidence of preeclampsia. Secondary outcomes were rates of hypertensive disorders of pregnancy, defined as preeclampsia and prenatal gestational hypertension, and gestational diabetes. Crude and adjusted odds ratios and 95% confidence intervals were calculated from univariate and multivariate logistic regression models. Adjustment covariates included maternal age (less than or equal to 21, 22-35, and over 35 years), body mass index (less than 25, 25 to less than 30, greater than or equal to 30 kg/m2), chronic hypertension (yes, no), and, for midpregnancy, rate of weight gain per week between early and midpregnancy assessments, treated as a continuous variable.
Conclusions and future directions
The nuMoM2b data are provocative because sleep apnea is a potentially modifiable risk factor for adverse pregnancy outcomes. While a majority of SDB cases identified during pregnancy were mild, the nuMoM2b data demonstrate that even modest elevations of AHI in pregnancy are associated with an increased risk of developing hypertensive disorders and an increased incidence of gestational diabetes.
Pregnancy is conceivably an ideal scenario in which to better understand the role of SDB treatment as a preventive strategy for reducing cardiometabolic morbidity as the time frame needed to measure incident outcomes after initiating therapy is significantly contracted. However, data regarding the role of OSA treatment with continuous positive airway pressure (CPAP) during pregnancy, both regarding its acceptability to patients and its therapeutic benefit, are extremely limited. Further research is needed to establish whether universal screening for and treating of SDB in pregnancy can mitigate the risks and consequences of hypertensive disorders of pregnancy and gestational diabetes. However, in the meantime, we have to recognize that as our obstetric patient population is becoming more obese, we will encounter more women with symptomatic SDB in pregnancy. It is well documented that patients with symptomatic SDB, those who report that their snoring leads to chronic sleep disruption and excessive daytime sleepiness, can benefit from CPAP in terms of sleep quality and daytime function. Therefore, in addition to encouraging women already prescribed CPAP to continue their therapy during pregnancy, obstetricians who encounter a patient reporting severe SDB symptoms should refer her to a sleep specialist for further evaluation.
Dr. Facco is assistant professor, department of obstetrics and gynecology, University of Pittsburgh, Magee-Women’s Hospital, Magee Women’s Research Institute.
References
1. Berry RB, Budhiraja R, Gottlieb DJ, et al. Rules for scoring respiratory events in sleep: Update of the 2007 AASM Manual for the Scoring of Sleep and Associated Events. Deliberations of the Sleep Apnea Definitions Task Force of the American Academy of Sleep Medicine. J Clin Sleep Med. 2012;8(5):597-619.
2. Park JG, Ramar K, Olson EJ. Updates on definition, consequences, and management of obstructive sleep apnea. Mayo Clin Proc. 2011;86(6):549-54; quiz, 554-5.
3. Iber C, Ancoli-Israel S, Chesson A, Quan S. The AASM Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications. 1st ed. Westchester, Ill.: American Academy of Sleep Medicine, 2007.
4. Peppard PE, Young T, Barnet JH, Palta M, Hagen EW, Hla KM. Increased prevalence of sleep-disordered breathing in adults. Am J Epidemiol. 2013 May 1;177(9):1006-14.
5. Young T, Palta M, Dempsey J, Skatrud J, Weber S, Badr S. The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med. 1993;328(17):1230-5.
6. Young T, Finn L, Austin D, Peterson A. Menopausal status and sleep-disordered breathing in the Wisconsin Sleep Cohort Study. Am J Respir Crit Care Med. 2003;167(9):1181-5.
7. Pien GW, Schwab RJ. Sleep disorders during pregnancy. Sleep. 2004;27(7):1405-17.
8. Hedman C, Pohjasvaara T, Tolonen U, Suhonen-Malm AS, Myllyla VV. Effects of pregnancy on mothers’ sleep. Sleep Med. 2002;3(1):37-42.
9. Pien GW, Fife D, Pack AI, Nkwuo JE, Schwab RJ. Changes in symptoms of sleep-disordered breathing during pregnancy. Sleep. 2005;28(10):1299-1305.
10. Facco FL, Kramer J, Ho KH, Zee PC, Grobman WA. Sleep disturbances in pregnancy. Obstet Gynecol. 2010;115(1):77-83.
11. Peppard PE, Young T, Palta M, Skatrud J. Prospective study of the association between sleep-disordered breathing and hypertension. N Engl J Med. 2000;342(19):1378-84.
12. Punjabi NM, Shahar E, Redline S, et al. Sleep-disordered breathing, glucose intolerance, and insulin resistance: The Sleep Heart Health Study. Am J Epidemiol. 2004;160(6):521-30.
13. Reichmuth KJ, Austin D, Skatrud JB, Young T. Association of sleep apnea and type II diabetes: A population-based study. Am J Respir Crit Care Med. 2005;172(12):1590-5.
14. Dempsey JA, Veasey SC, Morgan BJ, O’Donnell CP. Pathophysiology of sleep apnea. Physiol Rev. 2010;90(1):47-112.
15. Romero R, Badr MS. A role for sleep disorders in pregnancy complications: Challenges and opportunities. Am J Obstet Gynecol. 2014;210(1):3-11.
16. O’Brien LM, Bullough AS, Owusu JT, et al. Pregnancy-onset habitual snoring, gestational hypertension, and preeclampsia: Prospective cohort study. Am J Obstet Gynecol. 2012;207(6):487.e1-9
17. Chen YH, Kang JH, Lin CC, Wang IT, Keller JJ, Lin HC. Obstructive sleep apnea and the risk of adverse pregnancy outcomes. Am J Obstet Gynecol. 2012;206(2):136.e1-5.
18. Bourjeily G, Raker CA, Chalhoub M, Miller MA, et al. Pregnancy and fetal outcomes of symptoms of sleep-disordered breathing. Eur Respir J. 2010;36(4):849-55.
19. Louis J, Auckley D, Miladinovic B, et al. Perinatal outcomes associated with obstructive sleep apnea in obese pregnant women. Obstet Gynecol. 2012;120:1085-92.
20. Facco FL, Ouyang DW, Zee PC, et al. Implications of sleep-disordered breathing in pregnancy. Am J Obstet Gynecol. 2014 Jun;210(6):559.e1-6.
21. Pien GW, Pack AI, Jackson N, Maislin G, Macones GA, Schwab RJ. Risk factors for sleep-disordered breathing in pregnancy. Thorax. 2014;69(4):371-7.
22. Facco FL, Parker CB, Reddy UM, et al. NuMoM2b Sleep-Disordered Breathing study: Objectives and methods. Am J Obstet Gynecol. 2015 April;212(4):542.e1–542.e127.
23. Facco FL, Parker CB, Reddy UM, et al. Association between sleep-disordered breathing and hypertensive disorders of pregn ancy and gestational diabetes mellitus. Obstet Gynecol. ePub. 2016 Dec 2.
Background
Sleep-disordered breathing (SDB) conditions are characterized by abnormal respiratory patterns and abnormal gas exchange during sleep.1-3 Obstructive sleep apnea (OSA), the most common type of SDB, is characterized by repetitive episodes of airway narrowing during sleep that lead to respiratory disruption, hypoxia, and sleep fragmentation. In reproductive-aged women, epidemiologic studies suggest a 2% to 13% prevalence of OSA.4-6 Pregnancy is associated with changes that promote OSA, such as weight gain and edema of the upper airway.7 Frequent snoring, a common symptom of OSA, is endorsed by 15% to 25% of pregnant women.8-10 Health outcomes that have been linked to SDB in the nonpregnant population, such as hypertension and insulin-resistant diabetes, have clinically relevant correlates in pregnancy (preeclampsia, gestational diabetes).11-13
While several retrospective and cross-sectional studies suggest that SDB may increase the risk of developing hypertensive disorders and gestational diabetes during pregnancy,16-18 up until recently, there were limited and conflicting data from prospective observational cohorts in which SDB exposure and pregnancy outcomes have been methodically measured and confounding variables carefully considered.19-21 Louis et al.19 reported on a cohort of 175 obese women and demonstrated that women with SDB (apnea-hypopnea index greater than or equal to 5) were more likely to develop preeclampsia (adjusted odds ratio, 3.5; 95% CI, 1.3, 9.9). However, two other small studies failed to demonstrate a positive association between SDB and pregnancy-related hypertension, but one suggested a relationship between SDB and gestational diabetes.20,21
Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-Be Sleep-Disordered Breathing Substudy
The Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-Be Sleep-Disordered Breathing Substudy (nuMoM2b-SDB) was a prospective cohort study.22,23 Level 3 home sleep tests were performed using a six-channel monitor that was self-applied by the participant twice during pregnancy, first between 60 and 150 weeks of pregnancy and then again between 220 and 310 weeks. An apnea-hypopnea index (AHI) of at least 5 was used to define SDB. The study was powered to test the primary hypothesis that SDB occurring in pregnancy is associated with an increased incidence of preeclampsia. Secondary outcomes were rates of hypertensive disorders of pregnancy, defined as preeclampsia and prenatal gestational hypertension, and gestational diabetes. Crude and adjusted odds ratios and 95% confidence intervals were calculated from univariate and multivariate logistic regression models. Adjustment covariates included maternal age (less than or equal to 21, 22-35, and over 35 years), body mass index (less than 25, 25 to less than 30, greater than or equal to 30 kg/m2), chronic hypertension (yes, no), and, for midpregnancy, rate of weight gain per week between early and midpregnancy assessments, treated as a continuous variable.
Conclusions and future directions
The nuMoM2b data are provocative because sleep apnea is a potentially modifiable risk factor for adverse pregnancy outcomes. While a majority of SDB cases identified during pregnancy were mild, the nuMoM2b data demonstrate that even modest elevations of AHI in pregnancy are associated with an increased risk of developing hypertensive disorders and an increased incidence of gestational diabetes.
Pregnancy is conceivably an ideal scenario in which to better understand the role of SDB treatment as a preventive strategy for reducing cardiometabolic morbidity as the time frame needed to measure incident outcomes after initiating therapy is significantly contracted. However, data regarding the role of OSA treatment with continuous positive airway pressure (CPAP) during pregnancy, both regarding its acceptability to patients and its therapeutic benefit, are extremely limited. Further research is needed to establish whether universal screening for and treating of SDB in pregnancy can mitigate the risks and consequences of hypertensive disorders of pregnancy and gestational diabetes. However, in the meantime, we have to recognize that as our obstetric patient population is becoming more obese, we will encounter more women with symptomatic SDB in pregnancy. It is well documented that patients with symptomatic SDB, those who report that their snoring leads to chronic sleep disruption and excessive daytime sleepiness, can benefit from CPAP in terms of sleep quality and daytime function. Therefore, in addition to encouraging women already prescribed CPAP to continue their therapy during pregnancy, obstetricians who encounter a patient reporting severe SDB symptoms should refer her to a sleep specialist for further evaluation.
Dr. Facco is assistant professor, department of obstetrics and gynecology, University of Pittsburgh, Magee-Women’s Hospital, Magee Women’s Research Institute.
References
1. Berry RB, Budhiraja R, Gottlieb DJ, et al. Rules for scoring respiratory events in sleep: Update of the 2007 AASM Manual for the Scoring of Sleep and Associated Events. Deliberations of the Sleep Apnea Definitions Task Force of the American Academy of Sleep Medicine. J Clin Sleep Med. 2012;8(5):597-619.
2. Park JG, Ramar K, Olson EJ. Updates on definition, consequences, and management of obstructive sleep apnea. Mayo Clin Proc. 2011;86(6):549-54; quiz, 554-5.
3. Iber C, Ancoli-Israel S, Chesson A, Quan S. The AASM Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications. 1st ed. Westchester, Ill.: American Academy of Sleep Medicine, 2007.
4. Peppard PE, Young T, Barnet JH, Palta M, Hagen EW, Hla KM. Increased prevalence of sleep-disordered breathing in adults. Am J Epidemiol. 2013 May 1;177(9):1006-14.
5. Young T, Palta M, Dempsey J, Skatrud J, Weber S, Badr S. The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med. 1993;328(17):1230-5.
6. Young T, Finn L, Austin D, Peterson A. Menopausal status and sleep-disordered breathing in the Wisconsin Sleep Cohort Study. Am J Respir Crit Care Med. 2003;167(9):1181-5.
7. Pien GW, Schwab RJ. Sleep disorders during pregnancy. Sleep. 2004;27(7):1405-17.
8. Hedman C, Pohjasvaara T, Tolonen U, Suhonen-Malm AS, Myllyla VV. Effects of pregnancy on mothers’ sleep. Sleep Med. 2002;3(1):37-42.
9. Pien GW, Fife D, Pack AI, Nkwuo JE, Schwab RJ. Changes in symptoms of sleep-disordered breathing during pregnancy. Sleep. 2005;28(10):1299-1305.
10. Facco FL, Kramer J, Ho KH, Zee PC, Grobman WA. Sleep disturbances in pregnancy. Obstet Gynecol. 2010;115(1):77-83.
11. Peppard PE, Young T, Palta M, Skatrud J. Prospective study of the association between sleep-disordered breathing and hypertension. N Engl J Med. 2000;342(19):1378-84.
12. Punjabi NM, Shahar E, Redline S, et al. Sleep-disordered breathing, glucose intolerance, and insulin resistance: The Sleep Heart Health Study. Am J Epidemiol. 2004;160(6):521-30.
13. Reichmuth KJ, Austin D, Skatrud JB, Young T. Association of sleep apnea and type II diabetes: A population-based study. Am J Respir Crit Care Med. 2005;172(12):1590-5.
14. Dempsey JA, Veasey SC, Morgan BJ, O’Donnell CP. Pathophysiology of sleep apnea. Physiol Rev. 2010;90(1):47-112.
15. Romero R, Badr MS. A role for sleep disorders in pregnancy complications: Challenges and opportunities. Am J Obstet Gynecol. 2014;210(1):3-11.
16. O’Brien LM, Bullough AS, Owusu JT, et al. Pregnancy-onset habitual snoring, gestational hypertension, and preeclampsia: Prospective cohort study. Am J Obstet Gynecol. 2012;207(6):487.e1-9
17. Chen YH, Kang JH, Lin CC, Wang IT, Keller JJ, Lin HC. Obstructive sleep apnea and the risk of adverse pregnancy outcomes. Am J Obstet Gynecol. 2012;206(2):136.e1-5.
18. Bourjeily G, Raker CA, Chalhoub M, Miller MA, et al. Pregnancy and fetal outcomes of symptoms of sleep-disordered breathing. Eur Respir J. 2010;36(4):849-55.
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NETWORKS: Pneumonia Day, evaluating inhalers, tobacco taxes Chest Infections Clinical Pulmonary Medicine Interprofessional Team
Pneumonia Day: Today is the day to act!
This past November 12, we celebrated “Pneumonia Day,” named for a disease that has little connotation in the real world, because of the perception that we need only a short course of antibiotics to get better. Such is the origin of the term “walking pneumonia,” which emphasizes that we can still walk even while sick with pneumonia.
However, we recently experienced the most important moment of awareness related to this condition, when one of the U.S. presidential candidates became sick with that disease known as “pneumonia.”
Suddenly, the media devoted great interest to explore this condition, as if it were a new outbreak or a rare disease that could potentially kill someone. Even the health-care providers seem to believe that “pneumonia” is not a big deal, ignoring the fact that it is the most common infectious cause of death overall, and that it not only affects children but also the elderly and patients with poor immune systems.
One out of nine patients who are admitted to the hospital for pneumonia may die during the hospitalization, and one out of four patients who get admitted to an ICU may not survive the event.
However, it also highlights that pneumonia is more than just an acute disease, compromising the brain, heart, and kidneys. In the long run, even after surviving the hospitalization for pneumonia, it can kill and cause other well-known complications leading to death, such as myocardial infarction, arrhythmias, heart failure, and sudden cardiac death.
Please, stop for one moment and ask yourself about your role in preventing pneumonia and pneumonia-related deaths in your communities. The Chest Infections NetWork is here to help you advocate for the common goal of solving this problem.
Steering Committee Member
Delivery makes a difference: Providing inhaled medication to your patients
One might ask why CHEST (American College of Chest Physicians) and Sunovion developed a steering committee of experts in the field of obstructive lung disease to evaluate the knowledge, attitudes, beliefs, and practices of physicians and other health-care professionals related to inhalational medicines and devices. While inhalers are approved by the FDA Center for Drug Evaluation Research (CEDER) as drug and device combination, the process assesses reproducibility and shelf‐life but does not address the real‐world situation that each of us face with individual patients. How often do clinicians consider the characteristics of each delivery system, as well as the medication being delivered? One might be surprised at the answer.
Patients are frequently prescribed several types of devices with different instructions for optimal use. For example, dry powder inhalers often require high flow rates (30-90 L/min) to deaggregate powder pellets into particles less than 5 mcm, while metereddose inhalers require a slow inspiratory flow (less than 30 L/min). Patients who use both types of devices often confuse which inspiratory flow rate to use with which devices, despite proper education and training. This does not even take into consideration the variable number of steps required by various inhalational devices (which can be as few as 3 steps to as many as 12 steps). Additionally, studies demonstrate that peak inspiratory flow rates, inspiratory volumes, and drug deposition in the lungs may be influenced by gender, height, and weight; as well as by the degree of pulmonary reserve and hyperinflation.
Are there data to suggest that these questions impact the care of patients with severe asthma or COPD? I eagerly await the results of the survey.
Steering Committee Member
A California victory for tobacco control
Californians approved Proposition 56, “Cigarette Tax to Fund Healthcare, Tobacco Use Prevention, Research, and Law Enforcement.” This measure increases the excise tax on all forms of tobacco by $2.00. For the first time, it applies to electronic products that vaporize nicotine that were previously only subject to sales tax. This is in addition to federal excise taxes ($1.01) and state and local sales taxes ($0.50 to $0.60). (https://ballotpedia.org/California_Proposition_56,_Tobacco _Tax_Increase_(2016)
When Prop 56 goes into effect April 1, 2017, the average price of a package of cigarettes will increase to at least $7.89. Based on data from the Surgeon General’s report on “Preventing Tobacco Use Among Youth and Young Adults,” this tax increase should equate with a fall in smoking rates by about 12%. Youth and young adults are particularly susceptible to price increases, which helps prevent smoking initiation or continuation.
Tobacco-related health-care costs Californians $3.5 billion dollars annually (Official Voter Information Guide, 2016). Funds raised by Prop 56 will be used by state and local health programs such as Medi-Cal to defray the costs of smoking prevention pro
Prop 56 expands on tougher laws implemented in 2016 that expanded the workplace prohibition of smoking, increased fees for tobacco retailers and wholesalers, broadened the definition of smoking to include e-cigarettes, and increased the minimum age to purchase tobacco to 21 years old. Combined, these measures are expected to result in a further decline in tobacco usage in California.
Alan Roth, RRT, MS, FCCP
Steering Committee Member
Pneumonia Day: Today is the day to act!
This past November 12, we celebrated “Pneumonia Day,” named for a disease that has little connotation in the real world, because of the perception that we need only a short course of antibiotics to get better. Such is the origin of the term “walking pneumonia,” which emphasizes that we can still walk even while sick with pneumonia.
However, we recently experienced the most important moment of awareness related to this condition, when one of the U.S. presidential candidates became sick with that disease known as “pneumonia.”
Suddenly, the media devoted great interest to explore this condition, as if it were a new outbreak or a rare disease that could potentially kill someone. Even the health-care providers seem to believe that “pneumonia” is not a big deal, ignoring the fact that it is the most common infectious cause of death overall, and that it not only affects children but also the elderly and patients with poor immune systems.
One out of nine patients who are admitted to the hospital for pneumonia may die during the hospitalization, and one out of four patients who get admitted to an ICU may not survive the event.
However, it also highlights that pneumonia is more than just an acute disease, compromising the brain, heart, and kidneys. In the long run, even after surviving the hospitalization for pneumonia, it can kill and cause other well-known complications leading to death, such as myocardial infarction, arrhythmias, heart failure, and sudden cardiac death.
Please, stop for one moment and ask yourself about your role in preventing pneumonia and pneumonia-related deaths in your communities. The Chest Infections NetWork is here to help you advocate for the common goal of solving this problem.
Steering Committee Member
Delivery makes a difference: Providing inhaled medication to your patients
One might ask why CHEST (American College of Chest Physicians) and Sunovion developed a steering committee of experts in the field of obstructive lung disease to evaluate the knowledge, attitudes, beliefs, and practices of physicians and other health-care professionals related to inhalational medicines and devices. While inhalers are approved by the FDA Center for Drug Evaluation Research (CEDER) as drug and device combination, the process assesses reproducibility and shelf‐life but does not address the real‐world situation that each of us face with individual patients. How often do clinicians consider the characteristics of each delivery system, as well as the medication being delivered? One might be surprised at the answer.
Patients are frequently prescribed several types of devices with different instructions for optimal use. For example, dry powder inhalers often require high flow rates (30-90 L/min) to deaggregate powder pellets into particles less than 5 mcm, while metereddose inhalers require a slow inspiratory flow (less than 30 L/min). Patients who use both types of devices often confuse which inspiratory flow rate to use with which devices, despite proper education and training. This does not even take into consideration the variable number of steps required by various inhalational devices (which can be as few as 3 steps to as many as 12 steps). Additionally, studies demonstrate that peak inspiratory flow rates, inspiratory volumes, and drug deposition in the lungs may be influenced by gender, height, and weight; as well as by the degree of pulmonary reserve and hyperinflation.
Are there data to suggest that these questions impact the care of patients with severe asthma or COPD? I eagerly await the results of the survey.
Steering Committee Member
A California victory for tobacco control
Californians approved Proposition 56, “Cigarette Tax to Fund Healthcare, Tobacco Use Prevention, Research, and Law Enforcement.” This measure increases the excise tax on all forms of tobacco by $2.00. For the first time, it applies to electronic products that vaporize nicotine that were previously only subject to sales tax. This is in addition to federal excise taxes ($1.01) and state and local sales taxes ($0.50 to $0.60). (https://ballotpedia.org/California_Proposition_56,_Tobacco _Tax_Increase_(2016)
When Prop 56 goes into effect April 1, 2017, the average price of a package of cigarettes will increase to at least $7.89. Based on data from the Surgeon General’s report on “Preventing Tobacco Use Among Youth and Young Adults,” this tax increase should equate with a fall in smoking rates by about 12%. Youth and young adults are particularly susceptible to price increases, which helps prevent smoking initiation or continuation.
Tobacco-related health-care costs Californians $3.5 billion dollars annually (Official Voter Information Guide, 2016). Funds raised by Prop 56 will be used by state and local health programs such as Medi-Cal to defray the costs of smoking prevention pro
Prop 56 expands on tougher laws implemented in 2016 that expanded the workplace prohibition of smoking, increased fees for tobacco retailers and wholesalers, broadened the definition of smoking to include e-cigarettes, and increased the minimum age to purchase tobacco to 21 years old. Combined, these measures are expected to result in a further decline in tobacco usage in California.
Alan Roth, RRT, MS, FCCP
Steering Committee Member
Pneumonia Day: Today is the day to act!
This past November 12, we celebrated “Pneumonia Day,” named for a disease that has little connotation in the real world, because of the perception that we need only a short course of antibiotics to get better. Such is the origin of the term “walking pneumonia,” which emphasizes that we can still walk even while sick with pneumonia.
However, we recently experienced the most important moment of awareness related to this condition, when one of the U.S. presidential candidates became sick with that disease known as “pneumonia.”
Suddenly, the media devoted great interest to explore this condition, as if it were a new outbreak or a rare disease that could potentially kill someone. Even the health-care providers seem to believe that “pneumonia” is not a big deal, ignoring the fact that it is the most common infectious cause of death overall, and that it not only affects children but also the elderly and patients with poor immune systems.
One out of nine patients who are admitted to the hospital for pneumonia may die during the hospitalization, and one out of four patients who get admitted to an ICU may not survive the event.
However, it also highlights that pneumonia is more than just an acute disease, compromising the brain, heart, and kidneys. In the long run, even after surviving the hospitalization for pneumonia, it can kill and cause other well-known complications leading to death, such as myocardial infarction, arrhythmias, heart failure, and sudden cardiac death.
Please, stop for one moment and ask yourself about your role in preventing pneumonia and pneumonia-related deaths in your communities. The Chest Infections NetWork is here to help you advocate for the common goal of solving this problem.
Steering Committee Member
Delivery makes a difference: Providing inhaled medication to your patients
One might ask why CHEST (American College of Chest Physicians) and Sunovion developed a steering committee of experts in the field of obstructive lung disease to evaluate the knowledge, attitudes, beliefs, and practices of physicians and other health-care professionals related to inhalational medicines and devices. While inhalers are approved by the FDA Center for Drug Evaluation Research (CEDER) as drug and device combination, the process assesses reproducibility and shelf‐life but does not address the real‐world situation that each of us face with individual patients. How often do clinicians consider the characteristics of each delivery system, as well as the medication being delivered? One might be surprised at the answer.
Patients are frequently prescribed several types of devices with different instructions for optimal use. For example, dry powder inhalers often require high flow rates (30-90 L/min) to deaggregate powder pellets into particles less than 5 mcm, while metereddose inhalers require a slow inspiratory flow (less than 30 L/min). Patients who use both types of devices often confuse which inspiratory flow rate to use with which devices, despite proper education and training. This does not even take into consideration the variable number of steps required by various inhalational devices (which can be as few as 3 steps to as many as 12 steps). Additionally, studies demonstrate that peak inspiratory flow rates, inspiratory volumes, and drug deposition in the lungs may be influenced by gender, height, and weight; as well as by the degree of pulmonary reserve and hyperinflation.
Are there data to suggest that these questions impact the care of patients with severe asthma or COPD? I eagerly await the results of the survey.
Steering Committee Member
A California victory for tobacco control
Californians approved Proposition 56, “Cigarette Tax to Fund Healthcare, Tobacco Use Prevention, Research, and Law Enforcement.” This measure increases the excise tax on all forms of tobacco by $2.00. For the first time, it applies to electronic products that vaporize nicotine that were previously only subject to sales tax. This is in addition to federal excise taxes ($1.01) and state and local sales taxes ($0.50 to $0.60). (https://ballotpedia.org/California_Proposition_56,_Tobacco _Tax_Increase_(2016)
When Prop 56 goes into effect April 1, 2017, the average price of a package of cigarettes will increase to at least $7.89. Based on data from the Surgeon General’s report on “Preventing Tobacco Use Among Youth and Young Adults,” this tax increase should equate with a fall in smoking rates by about 12%. Youth and young adults are particularly susceptible to price increases, which helps prevent smoking initiation or continuation.
Tobacco-related health-care costs Californians $3.5 billion dollars annually (Official Voter Information Guide, 2016). Funds raised by Prop 56 will be used by state and local health programs such as Medi-Cal to defray the costs of smoking prevention pro
Prop 56 expands on tougher laws implemented in 2016 that expanded the workplace prohibition of smoking, increased fees for tobacco retailers and wholesalers, broadened the definition of smoking to include e-cigarettes, and increased the minimum age to purchase tobacco to 21 years old. Combined, these measures are expected to result in a further decline in tobacco usage in California.
Alan Roth, RRT, MS, FCCP
Steering Committee Member
This month in CHEST : Editor’s picks
Editorial
Spread the Word About CHEST for 2017: Collaboration With Elsevier, Publishing of Guidelines, More Multimedia Content, and Changes for Reviewers and Authors. By Dr. Richard S. Irwin; Dr. John E. Heffner; Jean Rice; Dr. Cynthia T. French; on behalf of the Editorial Leadership Team.
Point Counterpoint Editorial
POINT: Will New Anti-eosinophilic Drugs Be Useful In Asthma Management?
Yes. Dr. P.M. O’Byrne
No. Dr. P. Barnes
Giants in Chest Medicine
Dr. Claude Lenfant. By Dr. E.J. Roccella.
Special Feature
The Eighth Edition Lung Cancer Stage Classification. By Dr. F.C. Detterbeck, et al.
Evidence-based MedicineLiberation From Mechanical Ventilation in Critically Ill Adults: Executive Summary of an Official American College of Chest Physicians/American Thoracic Society Clinical Practice Guideline. By Dr. G.A. Schmidt, et al.
Original ResearchEffect of Procalcitonin Testing on Health-care Utilization and Costs in Critically Ill Patients in the United States. By Dr. R.A. Balk, et al.
Use of Palliative Care in Patients With End-Stage COPD and Receiving Home Oxygen: National Trends and Barriers to Care in the United States. By Dr. B. Rush, et al.
Editorial
Spread the Word About CHEST for 2017: Collaboration With Elsevier, Publishing of Guidelines, More Multimedia Content, and Changes for Reviewers and Authors. By Dr. Richard S. Irwin; Dr. John E. Heffner; Jean Rice; Dr. Cynthia T. French; on behalf of the Editorial Leadership Team.
Point Counterpoint Editorial
POINT: Will New Anti-eosinophilic Drugs Be Useful In Asthma Management?
Yes. Dr. P.M. O’Byrne
No. Dr. P. Barnes
Giants in Chest Medicine
Dr. Claude Lenfant. By Dr. E.J. Roccella.
Special Feature
The Eighth Edition Lung Cancer Stage Classification. By Dr. F.C. Detterbeck, et al.
Evidence-based MedicineLiberation From Mechanical Ventilation in Critically Ill Adults: Executive Summary of an Official American College of Chest Physicians/American Thoracic Society Clinical Practice Guideline. By Dr. G.A. Schmidt, et al.
Original ResearchEffect of Procalcitonin Testing on Health-care Utilization and Costs in Critically Ill Patients in the United States. By Dr. R.A. Balk, et al.
Use of Palliative Care in Patients With End-Stage COPD and Receiving Home Oxygen: National Trends and Barriers to Care in the United States. By Dr. B. Rush, et al.
Editorial
Spread the Word About CHEST for 2017: Collaboration With Elsevier, Publishing of Guidelines, More Multimedia Content, and Changes for Reviewers and Authors. By Dr. Richard S. Irwin; Dr. John E. Heffner; Jean Rice; Dr. Cynthia T. French; on behalf of the Editorial Leadership Team.
Point Counterpoint Editorial
POINT: Will New Anti-eosinophilic Drugs Be Useful In Asthma Management?
Yes. Dr. P.M. O’Byrne
No. Dr. P. Barnes
Giants in Chest Medicine
Dr. Claude Lenfant. By Dr. E.J. Roccella.
Special Feature
The Eighth Edition Lung Cancer Stage Classification. By Dr. F.C. Detterbeck, et al.
Evidence-based MedicineLiberation From Mechanical Ventilation in Critically Ill Adults: Executive Summary of an Official American College of Chest Physicians/American Thoracic Society Clinical Practice Guideline. By Dr. G.A. Schmidt, et al.
Original ResearchEffect of Procalcitonin Testing on Health-care Utilization and Costs in Critically Ill Patients in the United States. By Dr. R.A. Balk, et al.
Use of Palliative Care in Patients With End-Stage COPD and Receiving Home Oxygen: National Trends and Barriers to Care in the United States. By Dr. B. Rush, et al.
Introducing our new Editorial Board Members
In Memoriam
CHEST has been informed of the following members’ deaths. We extend our sincere condolences.
Anthony Cosentino, MD, FCCP (January 2016)
Ben Branscomb, MD (July 2016)
Steven Sahn, MD, FCCP (Aug 2016)
Thomas Aldrich, MD (September 2016)
John C. Baldwin, MD, FCCP (September 2016)
David Cugell, MD, FCCP (December 2016)
CHEST has been informed of the following members’ deaths. We extend our sincere condolences.
Anthony Cosentino, MD, FCCP (January 2016)
Ben Branscomb, MD (July 2016)
Steven Sahn, MD, FCCP (Aug 2016)
Thomas Aldrich, MD (September 2016)
John C. Baldwin, MD, FCCP (September 2016)
David Cugell, MD, FCCP (December 2016)
CHEST has been informed of the following members’ deaths. We extend our sincere condolences.
Anthony Cosentino, MD, FCCP (January 2016)
Ben Branscomb, MD (July 2016)
Steven Sahn, MD, FCCP (Aug 2016)
Thomas Aldrich, MD (September 2016)
John C. Baldwin, MD, FCCP (September 2016)
David Cugell, MD, FCCP (December 2016)
Winners-All at CHEST 2016
We all know that, with the great success of CHEST 2016, everyone who shared that event is a winner. But, we would especially like to call out some of the special winners who were recognized during our annual meeting.
CHEST Awards
College Medalist Award
Lewis J. Rubin, MD, FCCP
Distinguished Service Award
Kim D. French, MHSA, CAPPM, FCCP
Alfred Soffer Award for Editorial Excellence
Seth J. Koenig, MD, FCCP
Master Clinician Educator Award
Jack D. Buckley, MD, MPH, FCCP
Distinguished Scientist Honor Lecture
Jay Nadel, MD
Edward C. Rosenow III, MD, Master FCCP/Master Teacher Honor Lecture
Suhail Raoof, MBBS, FCCP
Murray Kornfeld Memorial Founders Lecture
Michael Niederman, MD, FCCP Pasquale Ciaglia Memorial Lecture Kevin L. Kovitz, MD, FCCP
Roger C. Bone Memorial Lecture
Robert A. Berg, MD Thomas L. Petty, MD, Master FCCP Memorial Lecture Nicola A. Hanania, MD, MS, FCCP Margaret Pfrommer Memorial Lecture in Long-term Mechanical Ventilation Thomas G. Keens, MD Om P. Sharma, MD, Master FCCP Memorial Lecture Robert P. Baughman, MD, FCCP
Early Career Educator
Gabriel Bosslet, MD, FCCP
CHEST Challenge Championship 2016
1st Place
The University of Arizona
Huthayfa Ateeli, MBBS Naser Mahmoud, MD
Muna Omar, MD, MBBS
PD: James L. Knepler Jr.
2nd Place
New York Methodist Hospital
Anu R. Jacob, MD
Stephen D. Milan, MD
Jordan Taillon, MD
PD: Anthony G. Saleh, MD, FCCP
3rd Place
Interfaith Medical Center
Chidozie C. Agu, MD
Saroj P. Kandel, MBBS Divya Salhan, MD, MBBS
PD: Marie Frances J. Schmidt, MD, FCCP
CHEST Foundation Grant Winners
GlaxoSmithKline Distinguished Scholar in Respiratory Health
Don Hayes Jr., MD, FCCP The Research Institute at Nationwide Children’s Hospital
Implications of the Lung Allocation Score in Prioritizing Critically Ill Patients for Lung Transplantation
Supported by GlaxoSmithKline.
2016 Research Grantees
Alice Turner, MBChB, MRCP, PhD
University of Birmingham, United Kingdom
CHEST Foundation and the Alpha-1 Foundation Research Grant in Alpha-1 Antitrypsin Deficiency
Improving Access to Augmentation: A Propensity-Matching Study Between the UK AATD Registry and AlphaNet
This grant is jointly supported by the CHEST Foundation and the Alpha-1 Foundation.
Robert Busch, MD
Brigham and Women’s Hospital, Channing Division of Network Medicine
CHEST Foundation Research Grant in Chronic Obstructive Pulmonary Disease
Methylation Quantitative Trait Loci: Markers of Race-Specific Disparities in African Americans With COPD
This grant is supported by AstraZeneca.
Clemens Grassberger, PhD
Massachusetts General Hospital – Harvard University
CHEST Foundation Research Grant in Lung Cancer
Dynamic FLT-PET as Biomarker for Early Response in Locally Advanced Lung Cancer Patients
This grant is supported by Genentech Inc.
Cristina Russo, MD, PhD
Bambino Gesù Children’s Hospital, Rome, Italy
CHEST Foundation Research Grant in Nontuberculous Mycobacteria
A Proteomic-Metaproteomic Analysis Approach Allows Identification of Drug Target Candidates for the Future Design of Preventive, Diagnostic, and Therapeutic Strategies Against Nontuberculous Mycobacteria Diseases
This grant is supported by Insmed.
Peter Leary, MD, MS
University of Washington
CHEST Foundation Research Grant in Pulmonary Arterial Hypertension
Expression Profiling in Pulmonary Arterial Hypertension
This grant is supported by Actelion Pharmaceuticals, US, Inc.
Brett Ley, MD
University of California, San Francisco
CHEST Foundation Research Grant in Pulmonary Fibrosis
Extracellular Circulation RNAs as Predictors of Disease Progression in Idiopathic Pulmonary Fibrosis
This grant is supported by Boehringer Ingelheim Pharmaceuticals & Genentech Inc.
Sydney Montesi, MD
Massachusetts General Hospital
CHEST Foundation Research Grant in Pulmonary Fibrosis
Gadofosveset-Enhanced Lung MRI to Detect Idiopathic Pulmonary Fibrosis Disease Activity
This grant is supported by Boehringer Ingelheim Pharmaceuticals & Genentech Inc.
Farbod Rahaghi, MD, PhD
Brigham and Women’s Hospital
CHEST Foundation Research Grant in Venous Thromboembolism
CT Scan-Based Markers for Prediction of Outcomes in Acute Pulmonary Embolism
This grant is supported by Daiichi Sankyo.
Catherine Oberg, MD
Icahn School of Medicine at Mount Sinai
CHEST Foundation Research Grant in Women’s Lung Health
Effects of Household Air Pollution on Airway Inflammation, Lung Function, and Respiratory Symptoms
This grant is supported in full by the CHEST Foundation.
2016 Community Service Grantee
Ethel Jane Carter, MD, FCCP
Warren Alpert School of Medicine at Brown University
CHEST Foundation Community Service Grant Honoring D. Robert McCaffree, MD, Master FCCP
East African Training Initiative ( EATI) in Pulmonary Medicine
2016 NetWorks Challenge Travel Grantees
Debarsee Banerjee, MS, MD
Women’s Health NetWork
Drew Harris, MD
Occupational and Environmental Health NetWork
Kerry Hena, MD
Occupational and Environmental Health NetWork
Amanpreet Kaur, MD
Women’s Health NetWork
2016 Diversity Travel Grant Winners
John B. Bishara, DO
Renato F. Blanco Jr., MD
Angel Coz-Yataco, MD Sherie A. Gause, MD
Anthony Nebor, MD
James T. Williams, MD
Alfred Soffer Research Award Winners
Kerry Hena, MD
Deepak Pradhan, MD, FCCP
Young Investigator Award Winners
Elizabeth Becker: Clinical Characteristics of Sarcoidosis in World Trade Center (WTC) Exposed Fire Department of the City of New York (FDNY) Firefighters
Daniel Altman, MD : Cost-Effectiveness of Universally Funding Smoking Cessation Pharmacotherapy
Top 3 Poster Winners
Epaminondas Kosmas, MD, PhD, FCCP : Bronchiectasis in Patients With COPD: An Irrelevant Imaging Finding or a Clinically Important Phenotype?
Mark Regala, MD, BS : Evaluation of Outcomes of Post-Extubation Dysphagia in Elderly Patients
Massa Zantah, MD : Correlation of Esophageal Dilatation and Pulmonary Fibrosis in Scleroderma
Runner-up: Alev Gurgun, MD : Pulmonary Rehabilitation Response in Elderly and Younger Patients With COPD
Case Report Slide Winners
John Egan, MD, BA : An Unusual Cause of Tracheal Stenosis Due to a Vascular Anomaly Successfully Managed With Silicone Airway Stenting Prior to Definitive Vascular Repair
Harprett Grewal, MD : Bladder PTLD: First Reported Case of Post-Transplant Lymphoproliferative Disorder (PTLD) in the Bladder in a Lung Transplant Recipient
Michael Fingerhood, MD, MPH : Pulmonary Overlap Histiocytosis: A Rare Case of Interstitial Lung Disease Due to Erdheim Chester Disease in a Patient With Langerhans Cell Histiocytosis and Myelodisplastic Syndrome
Yihenew Negatu, MD : Acute ST Elevation Myocardial Infarction Related to Carbon Monoxide Poisoning in a Young Patient Without Coronary Artery Disease
Stephanie Wappel, MD : False-Negative Pet Imaging in Early Stage Malignant Pleural Mesothelioma
Lina Miyakawa, MD : Restrictive EGFR Mutation
Jeffrey Bonenfant, DO : A Unique Case of Follicular Bronchiolitis
Melissa Myers, MD : Seeing the Forest and Not Just the Trees: A Case of Recurrent Fever, Cough, and Respiratory Failure
Carly Fabrizio, DO : An Unusual Case of Submassive Hemoptysis
Meilinh Thi, DO : A Case to Make Your Skin Crawl
Garrett Harp, MD : Lambertosis: A Lung Cancer Mimic
Malik Khan, MD : Pleural Epithelioid Hemangioendothelioma: A Case Report
Priya Patel, MD : A Troubling Trifecta: Pulmonary Alveolar Proteinosis and Pneumocystis Pneumonia in Acute Myeloid Leukemia
Atul Palkar, MD : SGLT2 Inhibitors: Mind the Gap
Ji Yeon Lee, MD : Making Unusual Connections: Fibrosing Mediastinitis Leading to Bronchoesophageal Fistula
Sailm Daouk, MD : A Rare Form of Invasive Aspergillus Infection in a Severely Immunocompromised Host
Venkata Ravi Kumar Angirekula, MD : Vanishing Lung
Stephen Milan, MD : An Unexpected Mass
Lelia Logue, MD : A Rare Cause of Dysphagia
Daniel Hershberger, MD : Rapidly Progressive Hypoxic Respiratory Failure After a Rash: A Case of Clinically Amyopathic Dermatomyositis (CADM)-Associated ILD
Fellow Case Report Poster Winners
Krishna Siva Sai Kakkera
An Unusual Case of Crypotococcal Pleural Effusion
George Cheng
Use of Laparoscopic Suction Irrigator With Rigid Pleuroscope in Medical Thoracoscopy
Matt Koroscil
Wong Type Dermatomyositis Complicated by Interstitial Lung Disease
Derek Hansen
Acute Fibrinous and Organizing Pneumonia Following Hematopoietic Stem Cell Transplantation Responsive to Corticosteroid Therapy
Ala Eddin Sagar
Pulmonary Embolism Caused by Thrombin-Based Hemostatic Matrix After Discectomy
Sandeep Chennadi
Systemic Lupus Erythematosus (SLE) With Refractory Bilateral Chylothorax and Chylous Ascites
Medical Student/Resident Case Report Poster Winners
Justin Fiala
Pulmonary Presentation Without Concurrent Bone Involvement in Erdheim-Chester Disease: A Report of Two Cases
Navitha Ramesh
A Fatal Migration: A Case of Intra-Cardiac Embolization of a Peripheral Stent
Humna Abid Memon
Use of Extracorporeal Membrane Oxygenation in Postpartum Management of a Patient With PAH
Vanessa Ohleyer
A Case of Unusual Anatomy for an Uncommon Mediastinal Tumor
Tanushree Gahlot
Three Unusual Presentations of Job’s Syndrome (Hyper Immunoglobulin E Syndrome)
NetWorks Challenge Winners
Round 1
Women’s Lung Health NetWork
Round 2
Practice and Operations NetWork-1st place
Home-Based Mechanical Ventilation and Neuromuscular Disease NetWorks – 2nd place
Round 3
Home-Based Mechanical Ventilation, Neuromuscular Disease, and the Women’s Lung Health NetWorks
CHEST Bingo Winners
Youseff Anid, MD, FCCP
Karen Cochran, ACNP
Molly Howsware, DO
Katie Jeans, MD
Genovena Medina, RN
Gregory Eisinger, MD
Saurabh Mittal, MD, MBBS
Navitha Ramesh, MD
Dalvinder Dhillon, MD
Teresita Saylor, MD, FCCP
Carl Kaplan, MD, FCCP
Vishal Patel, MBBS, FCCP
Erin Peterson, CNP
Lilian Pereira, DO
We all know that, with the great success of CHEST 2016, everyone who shared that event is a winner. But, we would especially like to call out some of the special winners who were recognized during our annual meeting.
CHEST Awards
College Medalist Award
Lewis J. Rubin, MD, FCCP
Distinguished Service Award
Kim D. French, MHSA, CAPPM, FCCP
Alfred Soffer Award for Editorial Excellence
Seth J. Koenig, MD, FCCP
Master Clinician Educator Award
Jack D. Buckley, MD, MPH, FCCP
Distinguished Scientist Honor Lecture
Jay Nadel, MD
Edward C. Rosenow III, MD, Master FCCP/Master Teacher Honor Lecture
Suhail Raoof, MBBS, FCCP
Murray Kornfeld Memorial Founders Lecture
Michael Niederman, MD, FCCP Pasquale Ciaglia Memorial Lecture Kevin L. Kovitz, MD, FCCP
Roger C. Bone Memorial Lecture
Robert A. Berg, MD Thomas L. Petty, MD, Master FCCP Memorial Lecture Nicola A. Hanania, MD, MS, FCCP Margaret Pfrommer Memorial Lecture in Long-term Mechanical Ventilation Thomas G. Keens, MD Om P. Sharma, MD, Master FCCP Memorial Lecture Robert P. Baughman, MD, FCCP
Early Career Educator
Gabriel Bosslet, MD, FCCP
CHEST Challenge Championship 2016
1st Place
The University of Arizona
Huthayfa Ateeli, MBBS Naser Mahmoud, MD
Muna Omar, MD, MBBS
PD: James L. Knepler Jr.
2nd Place
New York Methodist Hospital
Anu R. Jacob, MD
Stephen D. Milan, MD
Jordan Taillon, MD
PD: Anthony G. Saleh, MD, FCCP
3rd Place
Interfaith Medical Center
Chidozie C. Agu, MD
Saroj P. Kandel, MBBS Divya Salhan, MD, MBBS
PD: Marie Frances J. Schmidt, MD, FCCP
CHEST Foundation Grant Winners
GlaxoSmithKline Distinguished Scholar in Respiratory Health
Don Hayes Jr., MD, FCCP The Research Institute at Nationwide Children’s Hospital
Implications of the Lung Allocation Score in Prioritizing Critically Ill Patients for Lung Transplantation
Supported by GlaxoSmithKline.
2016 Research Grantees
Alice Turner, MBChB, MRCP, PhD
University of Birmingham, United Kingdom
CHEST Foundation and the Alpha-1 Foundation Research Grant in Alpha-1 Antitrypsin Deficiency
Improving Access to Augmentation: A Propensity-Matching Study Between the UK AATD Registry and AlphaNet
This grant is jointly supported by the CHEST Foundation and the Alpha-1 Foundation.
Robert Busch, MD
Brigham and Women’s Hospital, Channing Division of Network Medicine
CHEST Foundation Research Grant in Chronic Obstructive Pulmonary Disease
Methylation Quantitative Trait Loci: Markers of Race-Specific Disparities in African Americans With COPD
This grant is supported by AstraZeneca.
Clemens Grassberger, PhD
Massachusetts General Hospital – Harvard University
CHEST Foundation Research Grant in Lung Cancer
Dynamic FLT-PET as Biomarker for Early Response in Locally Advanced Lung Cancer Patients
This grant is supported by Genentech Inc.
Cristina Russo, MD, PhD
Bambino Gesù Children’s Hospital, Rome, Italy
CHEST Foundation Research Grant in Nontuberculous Mycobacteria
A Proteomic-Metaproteomic Analysis Approach Allows Identification of Drug Target Candidates for the Future Design of Preventive, Diagnostic, and Therapeutic Strategies Against Nontuberculous Mycobacteria Diseases
This grant is supported by Insmed.
Peter Leary, MD, MS
University of Washington
CHEST Foundation Research Grant in Pulmonary Arterial Hypertension
Expression Profiling in Pulmonary Arterial Hypertension
This grant is supported by Actelion Pharmaceuticals, US, Inc.
Brett Ley, MD
University of California, San Francisco
CHEST Foundation Research Grant in Pulmonary Fibrosis
Extracellular Circulation RNAs as Predictors of Disease Progression in Idiopathic Pulmonary Fibrosis
This grant is supported by Boehringer Ingelheim Pharmaceuticals & Genentech Inc.
Sydney Montesi, MD
Massachusetts General Hospital
CHEST Foundation Research Grant in Pulmonary Fibrosis
Gadofosveset-Enhanced Lung MRI to Detect Idiopathic Pulmonary Fibrosis Disease Activity
This grant is supported by Boehringer Ingelheim Pharmaceuticals & Genentech Inc.
Farbod Rahaghi, MD, PhD
Brigham and Women’s Hospital
CHEST Foundation Research Grant in Venous Thromboembolism
CT Scan-Based Markers for Prediction of Outcomes in Acute Pulmonary Embolism
This grant is supported by Daiichi Sankyo.
Catherine Oberg, MD
Icahn School of Medicine at Mount Sinai
CHEST Foundation Research Grant in Women’s Lung Health
Effects of Household Air Pollution on Airway Inflammation, Lung Function, and Respiratory Symptoms
This grant is supported in full by the CHEST Foundation.
2016 Community Service Grantee
Ethel Jane Carter, MD, FCCP
Warren Alpert School of Medicine at Brown University
CHEST Foundation Community Service Grant Honoring D. Robert McCaffree, MD, Master FCCP
East African Training Initiative ( EATI) in Pulmonary Medicine
2016 NetWorks Challenge Travel Grantees
Debarsee Banerjee, MS, MD
Women’s Health NetWork
Drew Harris, MD
Occupational and Environmental Health NetWork
Kerry Hena, MD
Occupational and Environmental Health NetWork
Amanpreet Kaur, MD
Women’s Health NetWork
2016 Diversity Travel Grant Winners
John B. Bishara, DO
Renato F. Blanco Jr., MD
Angel Coz-Yataco, MD Sherie A. Gause, MD
Anthony Nebor, MD
James T. Williams, MD
Alfred Soffer Research Award Winners
Kerry Hena, MD
Deepak Pradhan, MD, FCCP
Young Investigator Award Winners
Elizabeth Becker: Clinical Characteristics of Sarcoidosis in World Trade Center (WTC) Exposed Fire Department of the City of New York (FDNY) Firefighters
Daniel Altman, MD : Cost-Effectiveness of Universally Funding Smoking Cessation Pharmacotherapy
Top 3 Poster Winners
Epaminondas Kosmas, MD, PhD, FCCP : Bronchiectasis in Patients With COPD: An Irrelevant Imaging Finding or a Clinically Important Phenotype?
Mark Regala, MD, BS : Evaluation of Outcomes of Post-Extubation Dysphagia in Elderly Patients
Massa Zantah, MD : Correlation of Esophageal Dilatation and Pulmonary Fibrosis in Scleroderma
Runner-up: Alev Gurgun, MD : Pulmonary Rehabilitation Response in Elderly and Younger Patients With COPD
Case Report Slide Winners
John Egan, MD, BA : An Unusual Cause of Tracheal Stenosis Due to a Vascular Anomaly Successfully Managed With Silicone Airway Stenting Prior to Definitive Vascular Repair
Harprett Grewal, MD : Bladder PTLD: First Reported Case of Post-Transplant Lymphoproliferative Disorder (PTLD) in the Bladder in a Lung Transplant Recipient
Michael Fingerhood, MD, MPH : Pulmonary Overlap Histiocytosis: A Rare Case of Interstitial Lung Disease Due to Erdheim Chester Disease in a Patient With Langerhans Cell Histiocytosis and Myelodisplastic Syndrome
Yihenew Negatu, MD : Acute ST Elevation Myocardial Infarction Related to Carbon Monoxide Poisoning in a Young Patient Without Coronary Artery Disease
Stephanie Wappel, MD : False-Negative Pet Imaging in Early Stage Malignant Pleural Mesothelioma
Lina Miyakawa, MD : Restrictive EGFR Mutation
Jeffrey Bonenfant, DO : A Unique Case of Follicular Bronchiolitis
Melissa Myers, MD : Seeing the Forest and Not Just the Trees: A Case of Recurrent Fever, Cough, and Respiratory Failure
Carly Fabrizio, DO : An Unusual Case of Submassive Hemoptysis
Meilinh Thi, DO : A Case to Make Your Skin Crawl
Garrett Harp, MD : Lambertosis: A Lung Cancer Mimic
Malik Khan, MD : Pleural Epithelioid Hemangioendothelioma: A Case Report
Priya Patel, MD : A Troubling Trifecta: Pulmonary Alveolar Proteinosis and Pneumocystis Pneumonia in Acute Myeloid Leukemia
Atul Palkar, MD : SGLT2 Inhibitors: Mind the Gap
Ji Yeon Lee, MD : Making Unusual Connections: Fibrosing Mediastinitis Leading to Bronchoesophageal Fistula
Sailm Daouk, MD : A Rare Form of Invasive Aspergillus Infection in a Severely Immunocompromised Host
Venkata Ravi Kumar Angirekula, MD : Vanishing Lung
Stephen Milan, MD : An Unexpected Mass
Lelia Logue, MD : A Rare Cause of Dysphagia
Daniel Hershberger, MD : Rapidly Progressive Hypoxic Respiratory Failure After a Rash: A Case of Clinically Amyopathic Dermatomyositis (CADM)-Associated ILD
Fellow Case Report Poster Winners
Krishna Siva Sai Kakkera
An Unusual Case of Crypotococcal Pleural Effusion
George Cheng
Use of Laparoscopic Suction Irrigator With Rigid Pleuroscope in Medical Thoracoscopy
Matt Koroscil
Wong Type Dermatomyositis Complicated by Interstitial Lung Disease
Derek Hansen
Acute Fibrinous and Organizing Pneumonia Following Hematopoietic Stem Cell Transplantation Responsive to Corticosteroid Therapy
Ala Eddin Sagar
Pulmonary Embolism Caused by Thrombin-Based Hemostatic Matrix After Discectomy
Sandeep Chennadi
Systemic Lupus Erythematosus (SLE) With Refractory Bilateral Chylothorax and Chylous Ascites
Medical Student/Resident Case Report Poster Winners
Justin Fiala
Pulmonary Presentation Without Concurrent Bone Involvement in Erdheim-Chester Disease: A Report of Two Cases
Navitha Ramesh
A Fatal Migration: A Case of Intra-Cardiac Embolization of a Peripheral Stent
Humna Abid Memon
Use of Extracorporeal Membrane Oxygenation in Postpartum Management of a Patient With PAH
Vanessa Ohleyer
A Case of Unusual Anatomy for an Uncommon Mediastinal Tumor
Tanushree Gahlot
Three Unusual Presentations of Job’s Syndrome (Hyper Immunoglobulin E Syndrome)
NetWorks Challenge Winners
Round 1
Women’s Lung Health NetWork
Round 2
Practice and Operations NetWork-1st place
Home-Based Mechanical Ventilation and Neuromuscular Disease NetWorks – 2nd place
Round 3
Home-Based Mechanical Ventilation, Neuromuscular Disease, and the Women’s Lung Health NetWorks
CHEST Bingo Winners
Youseff Anid, MD, FCCP
Karen Cochran, ACNP
Molly Howsware, DO
Katie Jeans, MD
Genovena Medina, RN
Gregory Eisinger, MD
Saurabh Mittal, MD, MBBS
Navitha Ramesh, MD
Dalvinder Dhillon, MD
Teresita Saylor, MD, FCCP
Carl Kaplan, MD, FCCP
Vishal Patel, MBBS, FCCP
Erin Peterson, CNP
Lilian Pereira, DO
We all know that, with the great success of CHEST 2016, everyone who shared that event is a winner. But, we would especially like to call out some of the special winners who were recognized during our annual meeting.
CHEST Awards
College Medalist Award
Lewis J. Rubin, MD, FCCP
Distinguished Service Award
Kim D. French, MHSA, CAPPM, FCCP
Alfred Soffer Award for Editorial Excellence
Seth J. Koenig, MD, FCCP
Master Clinician Educator Award
Jack D. Buckley, MD, MPH, FCCP
Distinguished Scientist Honor Lecture
Jay Nadel, MD
Edward C. Rosenow III, MD, Master FCCP/Master Teacher Honor Lecture
Suhail Raoof, MBBS, FCCP
Murray Kornfeld Memorial Founders Lecture
Michael Niederman, MD, FCCP Pasquale Ciaglia Memorial Lecture Kevin L. Kovitz, MD, FCCP
Roger C. Bone Memorial Lecture
Robert A. Berg, MD Thomas L. Petty, MD, Master FCCP Memorial Lecture Nicola A. Hanania, MD, MS, FCCP Margaret Pfrommer Memorial Lecture in Long-term Mechanical Ventilation Thomas G. Keens, MD Om P. Sharma, MD, Master FCCP Memorial Lecture Robert P. Baughman, MD, FCCP
Early Career Educator
Gabriel Bosslet, MD, FCCP
CHEST Challenge Championship 2016
1st Place
The University of Arizona
Huthayfa Ateeli, MBBS Naser Mahmoud, MD
Muna Omar, MD, MBBS
PD: James L. Knepler Jr.
2nd Place
New York Methodist Hospital
Anu R. Jacob, MD
Stephen D. Milan, MD
Jordan Taillon, MD
PD: Anthony G. Saleh, MD, FCCP
3rd Place
Interfaith Medical Center
Chidozie C. Agu, MD
Saroj P. Kandel, MBBS Divya Salhan, MD, MBBS
PD: Marie Frances J. Schmidt, MD, FCCP
CHEST Foundation Grant Winners
GlaxoSmithKline Distinguished Scholar in Respiratory Health
Don Hayes Jr., MD, FCCP The Research Institute at Nationwide Children’s Hospital
Implications of the Lung Allocation Score in Prioritizing Critically Ill Patients for Lung Transplantation
Supported by GlaxoSmithKline.
2016 Research Grantees
Alice Turner, MBChB, MRCP, PhD
University of Birmingham, United Kingdom
CHEST Foundation and the Alpha-1 Foundation Research Grant in Alpha-1 Antitrypsin Deficiency
Improving Access to Augmentation: A Propensity-Matching Study Between the UK AATD Registry and AlphaNet
This grant is jointly supported by the CHEST Foundation and the Alpha-1 Foundation.
Robert Busch, MD
Brigham and Women’s Hospital, Channing Division of Network Medicine
CHEST Foundation Research Grant in Chronic Obstructive Pulmonary Disease
Methylation Quantitative Trait Loci: Markers of Race-Specific Disparities in African Americans With COPD
This grant is supported by AstraZeneca.
Clemens Grassberger, PhD
Massachusetts General Hospital – Harvard University
CHEST Foundation Research Grant in Lung Cancer
Dynamic FLT-PET as Biomarker for Early Response in Locally Advanced Lung Cancer Patients
This grant is supported by Genentech Inc.
Cristina Russo, MD, PhD
Bambino Gesù Children’s Hospital, Rome, Italy
CHEST Foundation Research Grant in Nontuberculous Mycobacteria
A Proteomic-Metaproteomic Analysis Approach Allows Identification of Drug Target Candidates for the Future Design of Preventive, Diagnostic, and Therapeutic Strategies Against Nontuberculous Mycobacteria Diseases
This grant is supported by Insmed.
Peter Leary, MD, MS
University of Washington
CHEST Foundation Research Grant in Pulmonary Arterial Hypertension
Expression Profiling in Pulmonary Arterial Hypertension
This grant is supported by Actelion Pharmaceuticals, US, Inc.
Brett Ley, MD
University of California, San Francisco
CHEST Foundation Research Grant in Pulmonary Fibrosis
Extracellular Circulation RNAs as Predictors of Disease Progression in Idiopathic Pulmonary Fibrosis
This grant is supported by Boehringer Ingelheim Pharmaceuticals & Genentech Inc.
Sydney Montesi, MD
Massachusetts General Hospital
CHEST Foundation Research Grant in Pulmonary Fibrosis
Gadofosveset-Enhanced Lung MRI to Detect Idiopathic Pulmonary Fibrosis Disease Activity
This grant is supported by Boehringer Ingelheim Pharmaceuticals & Genentech Inc.
Farbod Rahaghi, MD, PhD
Brigham and Women’s Hospital
CHEST Foundation Research Grant in Venous Thromboembolism
CT Scan-Based Markers for Prediction of Outcomes in Acute Pulmonary Embolism
This grant is supported by Daiichi Sankyo.
Catherine Oberg, MD
Icahn School of Medicine at Mount Sinai
CHEST Foundation Research Grant in Women’s Lung Health
Effects of Household Air Pollution on Airway Inflammation, Lung Function, and Respiratory Symptoms
This grant is supported in full by the CHEST Foundation.
2016 Community Service Grantee
Ethel Jane Carter, MD, FCCP
Warren Alpert School of Medicine at Brown University
CHEST Foundation Community Service Grant Honoring D. Robert McCaffree, MD, Master FCCP
East African Training Initiative ( EATI) in Pulmonary Medicine
2016 NetWorks Challenge Travel Grantees
Debarsee Banerjee, MS, MD
Women’s Health NetWork
Drew Harris, MD
Occupational and Environmental Health NetWork
Kerry Hena, MD
Occupational and Environmental Health NetWork
Amanpreet Kaur, MD
Women’s Health NetWork
2016 Diversity Travel Grant Winners
John B. Bishara, DO
Renato F. Blanco Jr., MD
Angel Coz-Yataco, MD Sherie A. Gause, MD
Anthony Nebor, MD
James T. Williams, MD
Alfred Soffer Research Award Winners
Kerry Hena, MD
Deepak Pradhan, MD, FCCP
Young Investigator Award Winners
Elizabeth Becker: Clinical Characteristics of Sarcoidosis in World Trade Center (WTC) Exposed Fire Department of the City of New York (FDNY) Firefighters
Daniel Altman, MD : Cost-Effectiveness of Universally Funding Smoking Cessation Pharmacotherapy
Top 3 Poster Winners
Epaminondas Kosmas, MD, PhD, FCCP : Bronchiectasis in Patients With COPD: An Irrelevant Imaging Finding or a Clinically Important Phenotype?
Mark Regala, MD, BS : Evaluation of Outcomes of Post-Extubation Dysphagia in Elderly Patients
Massa Zantah, MD : Correlation of Esophageal Dilatation and Pulmonary Fibrosis in Scleroderma
Runner-up: Alev Gurgun, MD : Pulmonary Rehabilitation Response in Elderly and Younger Patients With COPD
Case Report Slide Winners
John Egan, MD, BA : An Unusual Cause of Tracheal Stenosis Due to a Vascular Anomaly Successfully Managed With Silicone Airway Stenting Prior to Definitive Vascular Repair
Harprett Grewal, MD : Bladder PTLD: First Reported Case of Post-Transplant Lymphoproliferative Disorder (PTLD) in the Bladder in a Lung Transplant Recipient
Michael Fingerhood, MD, MPH : Pulmonary Overlap Histiocytosis: A Rare Case of Interstitial Lung Disease Due to Erdheim Chester Disease in a Patient With Langerhans Cell Histiocytosis and Myelodisplastic Syndrome
Yihenew Negatu, MD : Acute ST Elevation Myocardial Infarction Related to Carbon Monoxide Poisoning in a Young Patient Without Coronary Artery Disease
Stephanie Wappel, MD : False-Negative Pet Imaging in Early Stage Malignant Pleural Mesothelioma
Lina Miyakawa, MD : Restrictive EGFR Mutation
Jeffrey Bonenfant, DO : A Unique Case of Follicular Bronchiolitis
Melissa Myers, MD : Seeing the Forest and Not Just the Trees: A Case of Recurrent Fever, Cough, and Respiratory Failure
Carly Fabrizio, DO : An Unusual Case of Submassive Hemoptysis
Meilinh Thi, DO : A Case to Make Your Skin Crawl
Garrett Harp, MD : Lambertosis: A Lung Cancer Mimic
Malik Khan, MD : Pleural Epithelioid Hemangioendothelioma: A Case Report
Priya Patel, MD : A Troubling Trifecta: Pulmonary Alveolar Proteinosis and Pneumocystis Pneumonia in Acute Myeloid Leukemia
Atul Palkar, MD : SGLT2 Inhibitors: Mind the Gap
Ji Yeon Lee, MD : Making Unusual Connections: Fibrosing Mediastinitis Leading to Bronchoesophageal Fistula
Sailm Daouk, MD : A Rare Form of Invasive Aspergillus Infection in a Severely Immunocompromised Host
Venkata Ravi Kumar Angirekula, MD : Vanishing Lung
Stephen Milan, MD : An Unexpected Mass
Lelia Logue, MD : A Rare Cause of Dysphagia
Daniel Hershberger, MD : Rapidly Progressive Hypoxic Respiratory Failure After a Rash: A Case of Clinically Amyopathic Dermatomyositis (CADM)-Associated ILD
Fellow Case Report Poster Winners
Krishna Siva Sai Kakkera
An Unusual Case of Crypotococcal Pleural Effusion
George Cheng
Use of Laparoscopic Suction Irrigator With Rigid Pleuroscope in Medical Thoracoscopy
Matt Koroscil
Wong Type Dermatomyositis Complicated by Interstitial Lung Disease
Derek Hansen
Acute Fibrinous and Organizing Pneumonia Following Hematopoietic Stem Cell Transplantation Responsive to Corticosteroid Therapy
Ala Eddin Sagar
Pulmonary Embolism Caused by Thrombin-Based Hemostatic Matrix After Discectomy
Sandeep Chennadi
Systemic Lupus Erythematosus (SLE) With Refractory Bilateral Chylothorax and Chylous Ascites
Medical Student/Resident Case Report Poster Winners
Justin Fiala
Pulmonary Presentation Without Concurrent Bone Involvement in Erdheim-Chester Disease: A Report of Two Cases
Navitha Ramesh
A Fatal Migration: A Case of Intra-Cardiac Embolization of a Peripheral Stent
Humna Abid Memon
Use of Extracorporeal Membrane Oxygenation in Postpartum Management of a Patient With PAH
Vanessa Ohleyer
A Case of Unusual Anatomy for an Uncommon Mediastinal Tumor
Tanushree Gahlot
Three Unusual Presentations of Job’s Syndrome (Hyper Immunoglobulin E Syndrome)
NetWorks Challenge Winners
Round 1
Women’s Lung Health NetWork
Round 2
Practice and Operations NetWork-1st place
Home-Based Mechanical Ventilation and Neuromuscular Disease NetWorks – 2nd place
Round 3
Home-Based Mechanical Ventilation, Neuromuscular Disease, and the Women’s Lung Health NetWorks
CHEST Bingo Winners
Youseff Anid, MD, FCCP
Karen Cochran, ACNP
Molly Howsware, DO
Katie Jeans, MD
Genovena Medina, RN
Gregory Eisinger, MD
Saurabh Mittal, MD, MBBS
Navitha Ramesh, MD
Dalvinder Dhillon, MD
Teresita Saylor, MD, FCCP
Carl Kaplan, MD, FCCP
Vishal Patel, MBBS, FCCP
Erin Peterson, CNP
Lilian Pereira, DO
Joint CHEST-SGP Congress 2017
Basel, Switzerland June 7-9
Join leaders in CHEST medicine for a program designed by clinicians for clinicians.
The Joint Congress organized by CHEST and the Swiss Society of Pneumology will be held from June 7-9 in Basel, Switzerland. The program has been designed by more than 140 faculty members from both the United States and Europe, and it aims to provide a robust overview of all aspects of respiratory medicine through interactive sessions, plenary discussions, critical appraisals on controversial topics, and a review of the last year of published works.
The Joint Congress also provides the opportunity to take part in hands-on simulation in areas such as lung function techniques including body plethysmography, N2 washout techniques, and respiratory physiotherapy. Another hands-on opportunity is the interventional pneumology CHEST experience course, which will be held from 8:00 AM-11:00 AM on June 7 and 8 on site. This course will provide an overview of conventional and EBUS-guided TBNA, an anatomy identification of airway nodes, management of airway bleeding, and management of pneumothorax. This course is ideal for clinicians and health-care professionals with specialties in pulmonary, critical care, and intensive care medicine, as well as thoracic surgery.
The program at the Joint CHEST-SGP Congress aims to improve the patient care abilities of every attendee, as well as provide an ideal environment for networking with leaders in your field.
The call for abstracts remains open until January 24, 2017. The abstract topic areas are:
- Airway disease
- Interstitial lung disease
- Sleep/Breathing
- Lung cancer
- Epidemiology/Rehabilitation
- Interventional pneumology
- Pulmonary hypertension
- Basic science
- Thoracic surgery
- Pediatrics
All abstracts must be submitted via the Joint Congress abstracts web portal www.chest-sgp-switzerland2017.org.
CHEST recognizes the value of international outreach, and this Joint Congress advances that initiative. CHEST aims to standardize the patient care across borders and to encourage international collaboration to build the future of chest medicine. To further this mission, an application has been made to the European Accreditation Council for Continuing Medical Education (EACCME®) for CME accreditation of this event. Additionally, an application has been made to the European Board for Accreditation in Pneumology (EBAP) to provide quality assurance and CME for the event.
For more information or to register, visit the CHEST Joint Congress website www.chest-sgp-switzerland2017.org. Early registration ends on March 16, 2017.
Basel, Switzerland June 7-9
Join leaders in CHEST medicine for a program designed by clinicians for clinicians.
The Joint Congress organized by CHEST and the Swiss Society of Pneumology will be held from June 7-9 in Basel, Switzerland. The program has been designed by more than 140 faculty members from both the United States and Europe, and it aims to provide a robust overview of all aspects of respiratory medicine through interactive sessions, plenary discussions, critical appraisals on controversial topics, and a review of the last year of published works.
The Joint Congress also provides the opportunity to take part in hands-on simulation in areas such as lung function techniques including body plethysmography, N2 washout techniques, and respiratory physiotherapy. Another hands-on opportunity is the interventional pneumology CHEST experience course, which will be held from 8:00 AM-11:00 AM on June 7 and 8 on site. This course will provide an overview of conventional and EBUS-guided TBNA, an anatomy identification of airway nodes, management of airway bleeding, and management of pneumothorax. This course is ideal for clinicians and health-care professionals with specialties in pulmonary, critical care, and intensive care medicine, as well as thoracic surgery.
The program at the Joint CHEST-SGP Congress aims to improve the patient care abilities of every attendee, as well as provide an ideal environment for networking with leaders in your field.
The call for abstracts remains open until January 24, 2017. The abstract topic areas are:
- Airway disease
- Interstitial lung disease
- Sleep/Breathing
- Lung cancer
- Epidemiology/Rehabilitation
- Interventional pneumology
- Pulmonary hypertension
- Basic science
- Thoracic surgery
- Pediatrics
All abstracts must be submitted via the Joint Congress abstracts web portal www.chest-sgp-switzerland2017.org.
CHEST recognizes the value of international outreach, and this Joint Congress advances that initiative. CHEST aims to standardize the patient care across borders and to encourage international collaboration to build the future of chest medicine. To further this mission, an application has been made to the European Accreditation Council for Continuing Medical Education (EACCME®) for CME accreditation of this event. Additionally, an application has been made to the European Board for Accreditation in Pneumology (EBAP) to provide quality assurance and CME for the event.
For more information or to register, visit the CHEST Joint Congress website www.chest-sgp-switzerland2017.org. Early registration ends on March 16, 2017.
Basel, Switzerland June 7-9
Join leaders in CHEST medicine for a program designed by clinicians for clinicians.
The Joint Congress organized by CHEST and the Swiss Society of Pneumology will be held from June 7-9 in Basel, Switzerland. The program has been designed by more than 140 faculty members from both the United States and Europe, and it aims to provide a robust overview of all aspects of respiratory medicine through interactive sessions, plenary discussions, critical appraisals on controversial topics, and a review of the last year of published works.
The Joint Congress also provides the opportunity to take part in hands-on simulation in areas such as lung function techniques including body plethysmography, N2 washout techniques, and respiratory physiotherapy. Another hands-on opportunity is the interventional pneumology CHEST experience course, which will be held from 8:00 AM-11:00 AM on June 7 and 8 on site. This course will provide an overview of conventional and EBUS-guided TBNA, an anatomy identification of airway nodes, management of airway bleeding, and management of pneumothorax. This course is ideal for clinicians and health-care professionals with specialties in pulmonary, critical care, and intensive care medicine, as well as thoracic surgery.
The program at the Joint CHEST-SGP Congress aims to improve the patient care abilities of every attendee, as well as provide an ideal environment for networking with leaders in your field.
The call for abstracts remains open until January 24, 2017. The abstract topic areas are:
- Airway disease
- Interstitial lung disease
- Sleep/Breathing
- Lung cancer
- Epidemiology/Rehabilitation
- Interventional pneumology
- Pulmonary hypertension
- Basic science
- Thoracic surgery
- Pediatrics
All abstracts must be submitted via the Joint Congress abstracts web portal www.chest-sgp-switzerland2017.org.
CHEST recognizes the value of international outreach, and this Joint Congress advances that initiative. CHEST aims to standardize the patient care across borders and to encourage international collaboration to build the future of chest medicine. To further this mission, an application has been made to the European Accreditation Council for Continuing Medical Education (EACCME®) for CME accreditation of this event. Additionally, an application has been made to the European Board for Accreditation in Pneumology (EBAP) to provide quality assurance and CME for the event.
For more information or to register, visit the CHEST Joint Congress website www.chest-sgp-switzerland2017.org. Early registration ends on March 16, 2017.
Celebrating 10 years of GI & Hepatology News
Our January 2017 issue marks the 10-year anniversary of GI & Hepatology News (GIHN), the official newspaper of the AGA Institute. In 2007, the AGA created the newspaper with the intent to communicate current news and emerging trends and technologies in GI. I am honored to serve as the third editor of GIHN, following in the esteemed footsteps of Charles J. Lightdale MD, AGAF, and Colin W. Howden MD, AGAF, who worked diligently to establish the publication’s credibility and quality.
The January 2007 issue of GIHN featured current AGA Institute President Timothy C. Wang, MD, AGAF, on its front page. At the time, he served as the chair of the AGA Future Trends Committee, which predicted emerging forces that would alter our practice, including that computed tomographic colonography would likely become an accepted CRC screening option in a few years (the full report of the committee was published in Gastroenterology 2008:134:597-616). For our 2017 10-year anniversary, we will feature a “Flashback” column, written by myself and our associate editors, that highlights and discusses the most impactful GIHN articles from each year of the previous decade.
John I. Allen, MD, MBA, AGAF
Editor in Chief
Our January 2017 issue marks the 10-year anniversary of GI & Hepatology News (GIHN), the official newspaper of the AGA Institute. In 2007, the AGA created the newspaper with the intent to communicate current news and emerging trends and technologies in GI. I am honored to serve as the third editor of GIHN, following in the esteemed footsteps of Charles J. Lightdale MD, AGAF, and Colin W. Howden MD, AGAF, who worked diligently to establish the publication’s credibility and quality.
The January 2007 issue of GIHN featured current AGA Institute President Timothy C. Wang, MD, AGAF, on its front page. At the time, he served as the chair of the AGA Future Trends Committee, which predicted emerging forces that would alter our practice, including that computed tomographic colonography would likely become an accepted CRC screening option in a few years (the full report of the committee was published in Gastroenterology 2008:134:597-616). For our 2017 10-year anniversary, we will feature a “Flashback” column, written by myself and our associate editors, that highlights and discusses the most impactful GIHN articles from each year of the previous decade.
John I. Allen, MD, MBA, AGAF
Editor in Chief
Our January 2017 issue marks the 10-year anniversary of GI & Hepatology News (GIHN), the official newspaper of the AGA Institute. In 2007, the AGA created the newspaper with the intent to communicate current news and emerging trends and technologies in GI. I am honored to serve as the third editor of GIHN, following in the esteemed footsteps of Charles J. Lightdale MD, AGAF, and Colin W. Howden MD, AGAF, who worked diligently to establish the publication’s credibility and quality.
The January 2007 issue of GIHN featured current AGA Institute President Timothy C. Wang, MD, AGAF, on its front page. At the time, he served as the chair of the AGA Future Trends Committee, which predicted emerging forces that would alter our practice, including that computed tomographic colonography would likely become an accepted CRC screening option in a few years (the full report of the committee was published in Gastroenterology 2008:134:597-616). For our 2017 10-year anniversary, we will feature a “Flashback” column, written by myself and our associate editors, that highlights and discusses the most impactful GIHN articles from each year of the previous decade.
John I. Allen, MD, MBA, AGAF
Editor in Chief
