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MONTREAL — Increased vitamin D intake is not protective against melanoma, according to the results of the largest prospective cohort study presented by Dr. Maryam M. Asgari of Kaiser Permanente in Oakland, Calif.
Her study, presented at the annual meeting of the Society for Investigative Dermatology, suggests a trend toward a greater risk of melanoma with high dietary intake of vitamin D.
“When we looked at diet alone there was a slightly increased risk, but when we combined diet and supplement use, the risk washed out,” she said in an interview.
The cohort comprised 68,611 participants in the Vitamins and Cohort Lifestyle study. The average age was 62 years; 52% were female.
The researchers studied dietary intake of vitamin D and other nutrients in the preceding year, and supplement use over the past 10 years.
There was no evidence of an association between supplement use and an increased or decreased risk of melanoma, reported Dr. Asgari.
However, there was a nonsignificant trend toward a protective effect at the higher supplement doses.
When supplement use was examined in combination with dietary intake, there was no association with melanoma risk. However, high dietary intake alone was significantly associated with a slightly increased risk of melanoma.
MONTREAL — Increased vitamin D intake is not protective against melanoma, according to the results of the largest prospective cohort study presented by Dr. Maryam M. Asgari of Kaiser Permanente in Oakland, Calif.
Her study, presented at the annual meeting of the Society for Investigative Dermatology, suggests a trend toward a greater risk of melanoma with high dietary intake of vitamin D.
“When we looked at diet alone there was a slightly increased risk, but when we combined diet and supplement use, the risk washed out,” she said in an interview.
The cohort comprised 68,611 participants in the Vitamins and Cohort Lifestyle study. The average age was 62 years; 52% were female.
The researchers studied dietary intake of vitamin D and other nutrients in the preceding year, and supplement use over the past 10 years.
There was no evidence of an association between supplement use and an increased or decreased risk of melanoma, reported Dr. Asgari.
However, there was a nonsignificant trend toward a protective effect at the higher supplement doses.
When supplement use was examined in combination with dietary intake, there was no association with melanoma risk. However, high dietary intake alone was significantly associated with a slightly increased risk of melanoma.
MONTREAL — Increased vitamin D intake is not protective against melanoma, according to the results of the largest prospective cohort study presented by Dr. Maryam M. Asgari of Kaiser Permanente in Oakland, Calif.
Her study, presented at the annual meeting of the Society for Investigative Dermatology, suggests a trend toward a greater risk of melanoma with high dietary intake of vitamin D.
“When we looked at diet alone there was a slightly increased risk, but when we combined diet and supplement use, the risk washed out,” she said in an interview.
The cohort comprised 68,611 participants in the Vitamins and Cohort Lifestyle study. The average age was 62 years; 52% were female.
The researchers studied dietary intake of vitamin D and other nutrients in the preceding year, and supplement use over the past 10 years.
There was no evidence of an association between supplement use and an increased or decreased risk of melanoma, reported Dr. Asgari.
However, there was a nonsignificant trend toward a protective effect at the higher supplement doses.
When supplement use was examined in combination with dietary intake, there was no association with melanoma risk. However, high dietary intake alone was significantly associated with a slightly increased risk of melanoma.