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Study of Anxiety, Physical Conditions Is a First

Anxiety disorders are associated with a broad range of physical conditions, including respiratory diseases, gastrointestinal diseases, arthritic conditions, allergic conditions, thyroid diseases, and migraines, reported Dr. Jitender Sareen of the University of Manitoba, Winnipeg, and his associates.

The researchers conducted what they described as the first study aimed at systematically evaluating the association between anxiety disorders and physical conditions in a large epidemiologic sample that included standardized physician-based diagnoses. They used data from the German Health Survey, a nationally representative sample of more than 4,000 members of the German population aged 18–79 years in 1997–1999.

Subjects were assessed for 44 physical conditions and for panic disorder, agoraphobia, social phobia, simple phobia, generalized anxiety disorder, and obsessive-compulsive disorder, Dr. Sareen and his associates reported.

The presence of an anxiety disorder was associated with respiratory diseases such as asthma and chronic bronchitis; gastrointestinal diseases such as gastritis and ulcer; arthritic conditions such as inflammatory joint disease; allergic conditions such as hay fever, eczema, hives, food allergy, and conjunctivitis; thyroid diseases; and migraine headaches.

Anxiety disorders were not found to be associated with cardiac disease, hypertension, or diabetes in this study.

In most cases of comorbidity, onset of the anxiety disorder preceded onset of the physical conditions, the investigators said (Arch. Intern. Med. 2006;166:2109–16).

Compared with subjects who had these physical conditions alone, those who had comorbid anxiety disorders were more likely to report a poor quality of life and significant disability because of the physical illness.

“These findings underscore the importance of recognition of comorbidity of anxiety disorders among people who present with these physical health problems,” Dr. Sareen and his associates said.

The nature of this link between anxiety disorders and physical illnesses remains unclear. There may be a direct causal relationship mediated by biological mechanisms. Or there may be common genetic, environmental, or personality factors that underlie both types of disorders, the investigators noted.

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Anxiety disorders are associated with a broad range of physical conditions, including respiratory diseases, gastrointestinal diseases, arthritic conditions, allergic conditions, thyroid diseases, and migraines, reported Dr. Jitender Sareen of the University of Manitoba, Winnipeg, and his associates.

The researchers conducted what they described as the first study aimed at systematically evaluating the association between anxiety disorders and physical conditions in a large epidemiologic sample that included standardized physician-based diagnoses. They used data from the German Health Survey, a nationally representative sample of more than 4,000 members of the German population aged 18–79 years in 1997–1999.

Subjects were assessed for 44 physical conditions and for panic disorder, agoraphobia, social phobia, simple phobia, generalized anxiety disorder, and obsessive-compulsive disorder, Dr. Sareen and his associates reported.

The presence of an anxiety disorder was associated with respiratory diseases such as asthma and chronic bronchitis; gastrointestinal diseases such as gastritis and ulcer; arthritic conditions such as inflammatory joint disease; allergic conditions such as hay fever, eczema, hives, food allergy, and conjunctivitis; thyroid diseases; and migraine headaches.

Anxiety disorders were not found to be associated with cardiac disease, hypertension, or diabetes in this study.

In most cases of comorbidity, onset of the anxiety disorder preceded onset of the physical conditions, the investigators said (Arch. Intern. Med. 2006;166:2109–16).

Compared with subjects who had these physical conditions alone, those who had comorbid anxiety disorders were more likely to report a poor quality of life and significant disability because of the physical illness.

“These findings underscore the importance of recognition of comorbidity of anxiety disorders among people who present with these physical health problems,” Dr. Sareen and his associates said.

The nature of this link between anxiety disorders and physical illnesses remains unclear. There may be a direct causal relationship mediated by biological mechanisms. Or there may be common genetic, environmental, or personality factors that underlie both types of disorders, the investigators noted.

Anxiety disorders are associated with a broad range of physical conditions, including respiratory diseases, gastrointestinal diseases, arthritic conditions, allergic conditions, thyroid diseases, and migraines, reported Dr. Jitender Sareen of the University of Manitoba, Winnipeg, and his associates.

The researchers conducted what they described as the first study aimed at systematically evaluating the association between anxiety disorders and physical conditions in a large epidemiologic sample that included standardized physician-based diagnoses. They used data from the German Health Survey, a nationally representative sample of more than 4,000 members of the German population aged 18–79 years in 1997–1999.

Subjects were assessed for 44 physical conditions and for panic disorder, agoraphobia, social phobia, simple phobia, generalized anxiety disorder, and obsessive-compulsive disorder, Dr. Sareen and his associates reported.

The presence of an anxiety disorder was associated with respiratory diseases such as asthma and chronic bronchitis; gastrointestinal diseases such as gastritis and ulcer; arthritic conditions such as inflammatory joint disease; allergic conditions such as hay fever, eczema, hives, food allergy, and conjunctivitis; thyroid diseases; and migraine headaches.

Anxiety disorders were not found to be associated with cardiac disease, hypertension, or diabetes in this study.

In most cases of comorbidity, onset of the anxiety disorder preceded onset of the physical conditions, the investigators said (Arch. Intern. Med. 2006;166:2109–16).

Compared with subjects who had these physical conditions alone, those who had comorbid anxiety disorders were more likely to report a poor quality of life and significant disability because of the physical illness.

“These findings underscore the importance of recognition of comorbidity of anxiety disorders among people who present with these physical health problems,” Dr. Sareen and his associates said.

The nature of this link between anxiety disorders and physical illnesses remains unclear. There may be a direct causal relationship mediated by biological mechanisms. Or there may be common genetic, environmental, or personality factors that underlie both types of disorders, the investigators noted.

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