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Key clinical point: Patients with diarrhea-predominant irritable bowel syndrome (IBS-D) vs healthy controls had lower serum zinc levels and poor scores for the quality of life (QoL) and physical and psychological health, and higher scores for depression, anxiety, and stress.
Major finding: Patients with IBS-D vs healthy controls reported significantly lower serum zinc levels (P = .001); mean scores for overall QoL and general health (53.48 vs 72.74; P ≤ .001), physical health (59.59 vs 71.30; P ≤ .001), and psychological health (55.80 vs 65.22; P ≤ .001); and higher mean scores for depression (P = .014), anxiety (P = .005), and stress (P = .001). Higher dietary zinc intake improved body image in patients with IBS-D (r 0.266; P = .044) without significantly influencing other parameters.
Study details: This was a case-control study including patients newly diagnosed with IBS-D (n = 61) and matched healthy controls (n = 61).
Disclosures: This study was supported by the Vice-Chancellor for Research of Isfahan University of Medical Sciences. The authors declared no conflicts of interest.
Source: Rezazadegan M et al. Sci Rep. 2022 Jun 29. doi: 10.1038/s41598-022-15080-2.
Key clinical point: Patients with diarrhea-predominant irritable bowel syndrome (IBS-D) vs healthy controls had lower serum zinc levels and poor scores for the quality of life (QoL) and physical and psychological health, and higher scores for depression, anxiety, and stress.
Major finding: Patients with IBS-D vs healthy controls reported significantly lower serum zinc levels (P = .001); mean scores for overall QoL and general health (53.48 vs 72.74; P ≤ .001), physical health (59.59 vs 71.30; P ≤ .001), and psychological health (55.80 vs 65.22; P ≤ .001); and higher mean scores for depression (P = .014), anxiety (P = .005), and stress (P = .001). Higher dietary zinc intake improved body image in patients with IBS-D (r 0.266; P = .044) without significantly influencing other parameters.
Study details: This was a case-control study including patients newly diagnosed with IBS-D (n = 61) and matched healthy controls (n = 61).
Disclosures: This study was supported by the Vice-Chancellor for Research of Isfahan University of Medical Sciences. The authors declared no conflicts of interest.
Source: Rezazadegan M et al. Sci Rep. 2022 Jun 29. doi: 10.1038/s41598-022-15080-2.
Key clinical point: Patients with diarrhea-predominant irritable bowel syndrome (IBS-D) vs healthy controls had lower serum zinc levels and poor scores for the quality of life (QoL) and physical and psychological health, and higher scores for depression, anxiety, and stress.
Major finding: Patients with IBS-D vs healthy controls reported significantly lower serum zinc levels (P = .001); mean scores for overall QoL and general health (53.48 vs 72.74; P ≤ .001), physical health (59.59 vs 71.30; P ≤ .001), and psychological health (55.80 vs 65.22; P ≤ .001); and higher mean scores for depression (P = .014), anxiety (P = .005), and stress (P = .001). Higher dietary zinc intake improved body image in patients with IBS-D (r 0.266; P = .044) without significantly influencing other parameters.
Study details: This was a case-control study including patients newly diagnosed with IBS-D (n = 61) and matched healthy controls (n = 61).
Disclosures: This study was supported by the Vice-Chancellor for Research of Isfahan University of Medical Sciences. The authors declared no conflicts of interest.
Source: Rezazadegan M et al. Sci Rep. 2022 Jun 29. doi: 10.1038/s41598-022-15080-2.