Higher postoperative CONUT scores predict poor outcomes in small HCC after liver resection

Key clinical point: The postoperative controlling nutritional status (PoCONUT) score was an independent predictor of both overall survival and recurrence-free survival in small HCC patients who underwent liver resection; higher scores were associated with decreased survival.

Major finding: Overall survival at 1, 3, and 5 years was 95.4 %, 81.2, and 63.3 %, respectively, in the low PoCONUT group, vs 88.7 %, 63.0, and 44.2 %, respectively, in the high PoCONUT group (P = 0.009). Similarly, recurrence-free survival at 1, 3, and 5 years was 80.4 %, 57.5, and 49.5 %, respectively, vs 66.1 %, 40.3%, and 31.0 %, respectively, in the low and high groups.

Study details: The data come from a retrospective, case-control study including 547 consecutive adult patients with small HCC who underwent liver resection between February 2007 and December 2015; patients were divided into low (382 patients) and high (165 patients) groups according to postoperative controlling nutritional status (PoCONUT) scores (2 or less; 3 or greater).

Disclosures: The study was supported by the National Natural Science Foundation of China. The researchers had no financial conflicts to disclose.

Source: Peng W et al. BMC Surg. 2021 Sep 7. doi: 10.1186/s12893-021-01334-9.

Key clinical point: The postoperative controlling nutritional status (PoCONUT) score was an independent predictor of both overall survival and recurrence-free survival in small HCC patients who underwent liver resection; higher scores were associated with decreased survival.

Major finding: Overall survival at 1, 3, and 5 years was 95.4 %, 81.2, and 63.3 %, respectively, in the low PoCONUT group, vs 88.7 %, 63.0, and 44.2 %, respectively, in the high PoCONUT group (P = 0.009). Similarly, recurrence-free survival at 1, 3, and 5 years was 80.4 %, 57.5, and 49.5 %, respectively, vs 66.1 %, 40.3%, and 31.0 %, respectively, in the low and high groups.

Study details: The data come from a retrospective, case-control study including 547 consecutive adult patients with small HCC who underwent liver resection between February 2007 and December 2015; patients were divided into low (382 patients) and high (165 patients) groups according to postoperative controlling nutritional status (PoCONUT) scores (2 or less; 3 or greater).

Disclosures: The study was supported by the National Natural Science Foundation of China. The researchers had no financial conflicts to disclose.

Source: Peng W et al. BMC Surg. 2021 Sep 7. doi: 10.1186/s12893-021-01334-9.

Key clinical point: The postoperative controlling nutritional status (PoCONUT) score was an independent predictor of both overall survival and recurrence-free survival in small HCC patients who underwent liver resection; higher scores were associated with decreased survival.

Major finding: Overall survival at 1, 3, and 5 years was 95.4 %, 81.2, and 63.3 %, respectively, in the low PoCONUT group, vs 88.7 %, 63.0, and 44.2 %, respectively, in the high PoCONUT group (P = 0.009). Similarly, recurrence-free survival at 1, 3, and 5 years was 80.4 %, 57.5, and 49.5 %, respectively, vs 66.1 %, 40.3%, and 31.0 %, respectively, in the low and high groups.

Study details: The data come from a retrospective, case-control study including 547 consecutive adult patients with small HCC who underwent liver resection between February 2007 and December 2015; patients were divided into low (382 patients) and high (165 patients) groups according to postoperative controlling nutritional status (PoCONUT) scores (2 or less; 3 or greater).

Disclosures: The study was supported by the National Natural Science Foundation of China. The researchers had no financial conflicts to disclose.

Source: Peng W et al. BMC Surg. 2021 Sep 7. doi: 10.1186/s12893-021-01334-9.