Dietary vitamin D intake tied to lower risk for colorectal cancer in patients at high CV risk

Key clinical point: A higher dietary vitamin D intake was associated with reduced risk for colorectal cancer (CRC) and colon cancer in older individuals at high cardiovascular (CV) risk.

Major finding: After excluding individuals consuming vitamin D and/or calcium medication or prescribed supplements at baseline, those in highest vs. lowest quartile of vitamin D intake had 48% (hazard ratio [HR], 0.52; 95% confidence interval [CI], 0.28-0.96) and 56% (HR, 0.41; 95% CI, 0.12-0.85) lower risk of developing CRC and colon cancer alone, respectively.

Study details: Findings are from an analysis of 7,216 men and women aged between 55 and 80 years and at high CV risk from the PREvención con DIeta MEDiterránea study.

Disclosures: Spanish Instituto de Salud Carlos III (ISCIII) is funded by FEDER and supported by the official funding agency for biomedical research of the Spanish government, ISCIII, and others. J Salas‐Salvadó declared being a member of and receiving grants/research support, honoraria, and personal fees from various sources. The other authors declared no conflicts of interest.

Source: Hernández-Alonso P et al. Eur J Nutr. 2021 May 28. doi: 10.1007/s00394-021-02585-1.

Key clinical point: A higher dietary vitamin D intake was associated with reduced risk for colorectal cancer (CRC) and colon cancer in older individuals at high cardiovascular (CV) risk.

Major finding: After excluding individuals consuming vitamin D and/or calcium medication or prescribed supplements at baseline, those in highest vs. lowest quartile of vitamin D intake had 48% (hazard ratio [HR], 0.52; 95% confidence interval [CI], 0.28-0.96) and 56% (HR, 0.41; 95% CI, 0.12-0.85) lower risk of developing CRC and colon cancer alone, respectively.

Study details: Findings are from an analysis of 7,216 men and women aged between 55 and 80 years and at high CV risk from the PREvención con DIeta MEDiterránea study.

Disclosures: Spanish Instituto de Salud Carlos III (ISCIII) is funded by FEDER and supported by the official funding agency for biomedical research of the Spanish government, ISCIII, and others. J Salas‐Salvadó declared being a member of and receiving grants/research support, honoraria, and personal fees from various sources. The other authors declared no conflicts of interest.

Source: Hernández-Alonso P et al. Eur J Nutr. 2021 May 28. doi: 10.1007/s00394-021-02585-1.

Key clinical point: A higher dietary vitamin D intake was associated with reduced risk for colorectal cancer (CRC) and colon cancer in older individuals at high cardiovascular (CV) risk.

Major finding: After excluding individuals consuming vitamin D and/or calcium medication or prescribed supplements at baseline, those in highest vs. lowest quartile of vitamin D intake had 48% (hazard ratio [HR], 0.52; 95% confidence interval [CI], 0.28-0.96) and 56% (HR, 0.41; 95% CI, 0.12-0.85) lower risk of developing CRC and colon cancer alone, respectively.

Study details: Findings are from an analysis of 7,216 men and women aged between 55 and 80 years and at high CV risk from the PREvención con DIeta MEDiterránea study.

Disclosures: Spanish Instituto de Salud Carlos III (ISCIII) is funded by FEDER and supported by the official funding agency for biomedical research of the Spanish government, ISCIII, and others. J Salas‐Salvadó declared being a member of and receiving grants/research support, honoraria, and personal fees from various sources. The other authors declared no conflicts of interest.

Source: Hernández-Alonso P et al. Eur J Nutr. 2021 May 28. doi: 10.1007/s00394-021-02585-1.