Reuters Health

NEW YORK (Reuters Health) - Bisphosphonate use is associated with better survival in patients admitted to the intensive care unit (ICU), according to Australian researchers.

As Dr. Paul Lee told Reuters Health by email, "Bone loss in critical illness may have wider effects on the body beyond bone itself, and bisphosphonates, by reducing bone loss, may attenuate these potentially adverse effects on the body."

Increased bone resorption is known to predict mortality in the community setting, Dr. Lee of the Gavan Institute of Medical Research in Sydney and colleagues note in the Journal of Clinical Endocrinology and Metabolism, online January 18. The team theorized that mortality would be lower among patients treated with bisphosphonates prior to their acute illness.

To investigate, they examined data on more than 7,800 patients admitted to the ICU between 2003 and 2014; 245 had received bisphosphonates before admission.

The bisphosphonate users were older and had more co-morbidities, yet their in-hospital mortality rate was significantly lower than that of non-users(mortality rate ratio, 0.41; p<0.01). The difference remained significant after adjusting for factors including age, sex, and principal diagnosis.

Bisphosphonate-associated survival benefit was independent of vitamin D use, but bisphosphonate and vitamin D co-use was associated with a further reduction in mortality (MRR, 0.38).

A substudy involving CT scans of 37 patients with preadmission bisphosphonate use and 74 matched patients without such use found that baseline bone density was significantly lower among bisphosphonate users. However, all users survived admission whereas six of the non-users died.

The researchers speculate that the apparent benefits of bisphosphonate "may be partly related to modulation of systemic inflammation through antibone resorption."

However, Dr. Lee made it clear that "causality is not proven in the study, and prospective intervention trials are required to evaluate effects of bisphosphonates in critical illness."

NEW YORK (Reuters Health) - Bisphosphonate use is associated with better survival in patients admitted to the intensive care unit (ICU), according to Australian researchers.

As Dr. Paul Lee told Reuters Health by email, "Bone loss in critical illness may have wider effects on the body beyond bone itself, and bisphosphonates, by reducing bone loss, may attenuate these potentially adverse effects on the body."

Increased bone resorption is known to predict mortality in the community setting, Dr. Lee of the Gavan Institute of Medical Research in Sydney and colleagues note in the Journal of Clinical Endocrinology and Metabolism, online January 18. The team theorized that mortality would be lower among patients treated with bisphosphonates prior to their acute illness.

To investigate, they examined data on more than 7,800 patients admitted to the ICU between 2003 and 2014; 245 had received bisphosphonates before admission.

The bisphosphonate users were older and had more co-morbidities, yet their in-hospital mortality rate was significantly lower than that of non-users(mortality rate ratio, 0.41; p<0.01). The difference remained significant after adjusting for factors including age, sex, and principal diagnosis.

Bisphosphonate-associated survival benefit was independent of vitamin D use, but bisphosphonate and vitamin D co-use was associated with a further reduction in mortality (MRR, 0.38).

A substudy involving CT scans of 37 patients with preadmission bisphosphonate use and 74 matched patients without such use found that baseline bone density was significantly lower among bisphosphonate users. However, all users survived admission whereas six of the non-users died.

The researchers speculate that the apparent benefits of bisphosphonate "may be partly related to modulation of systemic inflammation through antibone resorption."

However, Dr. Lee made it clear that "causality is not proven in the study, and prospective intervention trials are required to evaluate effects of bisphosphonates in critical illness."

NEW YORK (Reuters Health) - Bisphosphonate use is associated with better survival in patients admitted to the intensive care unit (ICU), according to Australian researchers.

As Dr. Paul Lee told Reuters Health by email, "Bone loss in critical illness may have wider effects on the body beyond bone itself, and bisphosphonates, by reducing bone loss, may attenuate these potentially adverse effects on the body."

Increased bone resorption is known to predict mortality in the community setting, Dr. Lee of the Gavan Institute of Medical Research in Sydney and colleagues note in the Journal of Clinical Endocrinology and Metabolism, online January 18. The team theorized that mortality would be lower among patients treated with bisphosphonates prior to their acute illness.

To investigate, they examined data on more than 7,800 patients admitted to the ICU between 2003 and 2014; 245 had received bisphosphonates before admission.

The bisphosphonate users were older and had more co-morbidities, yet their in-hospital mortality rate was significantly lower than that of non-users(mortality rate ratio, 0.41; p<0.01). The difference remained significant after adjusting for factors including age, sex, and principal diagnosis.

Bisphosphonate-associated survival benefit was independent of vitamin D use, but bisphosphonate and vitamin D co-use was associated with a further reduction in mortality (MRR, 0.38).

A substudy involving CT scans of 37 patients with preadmission bisphosphonate use and 74 matched patients without such use found that baseline bone density was significantly lower among bisphosphonate users. However, all users survived admission whereas six of the non-users died.

The researchers speculate that the apparent benefits of bisphosphonate "may be partly related to modulation of systemic inflammation through antibone resorption."

However, Dr. Lee made it clear that "causality is not proven in the study, and prospective intervention trials are required to evaluate effects of bisphosphonates in critical illness."

NEW YORK (Reuters Health) - Myocardial infarction (MI) patients who are transferred to another hospital for care are less likely to be followed up and more likely to be readmitted to the hospital, new findings show.

"This group of patients may represent a vulnerable population and we really need to come up with specific strategies to make their post-discharge transition back to their local community as seamless as possible," corresponding author Dr. Amit Vora, of Duke University in Durham, North Carolina, told Reuters Health.

Many patients admitted to their local hospital for acute MI must be transferred to another hospital for care, for example, to receive revascularization, Dr. Vora and his team note in their report, to be published online in Circulation: Cardiovascular Quality and outcomes. Logistical factors may lead to poor communication and coordination when it's time for the patient to be transferred back to their community, they add, which could be particularly problematic for older patients who may have more comorbidity and require closer follow-up after discharge.

To investigate, the researchers looked at outcomes for 39,136 acute MI patients 65 and older who were treated between 2007 and 2010 at 451 hospitals participating in Acute Coronary Treatment and Intervention Outcomes Network Registry-Get With the Guidelines.

Thirty-six percent of patients were transferred to another hospital for acute MI care, traveling a median of 43 miles.Within 30 days of discharge, 69.9% of the transferred patients had received outpatient follow-up, versus 78.2% of direct-arrival patients.

The adjusted risk of readmission for any cause was 14.5% for transferred patients versus 14% for direct-admit patients, while the risk of readmission for cardiovascular causes was 9.5% for

transferred patients and 9.1% for the direct-admit patients.However, the risk adjusted 30-day mortality was 1.6% for each group.

"Post-discharge care for acute MI patients is a performance measure, and we do track how often these patients are admitted

to the hospital following their discharge," Dr. Vora said. "A big focus of quality improvement is identifying strategies to reduce rehospitalization."

The next step in the research will be to identify the specific barriers to receiving follow-up care for transferred patients, he added, and then "define clear pathways and clear plans following discharge to ensure that these patients receive the care and the follow-up that they need."

The Agency for Healthcare Research and Quality funded this research. Three coauthors reported relevant relationships.

NEW YORK (Reuters Health) - Myocardial infarction (MI) patients who are transferred to another hospital for care are less likely to be followed up and more likely to be readmitted to the hospital, new findings show.

"This group of patients may represent a vulnerable population and we really need to come up with specific strategies to make their post-discharge transition back to their local community as seamless as possible," corresponding author Dr. Amit Vora, of Duke University in Durham, North Carolina, told Reuters Health.

Many patients admitted to their local hospital for acute MI must be transferred to another hospital for care, for example, to receive revascularization, Dr. Vora and his team note in their report, to be published online in Circulation: Cardiovascular Quality and outcomes. Logistical factors may lead to poor communication and coordination when it's time for the patient to be transferred back to their community, they add, which could be particularly problematic for older patients who may have more comorbidity and require closer follow-up after discharge.

To investigate, the researchers looked at outcomes for 39,136 acute MI patients 65 and older who were treated between 2007 and 2010 at 451 hospitals participating in Acute Coronary Treatment and Intervention Outcomes Network Registry-Get With the Guidelines.

Thirty-six percent of patients were transferred to another hospital for acute MI care, traveling a median of 43 miles.Within 30 days of discharge, 69.9% of the transferred patients had received outpatient follow-up, versus 78.2% of direct-arrival patients.

The adjusted risk of readmission for any cause was 14.5% for transferred patients versus 14% for direct-admit patients, while the risk of readmission for cardiovascular causes was 9.5% for

transferred patients and 9.1% for the direct-admit patients.However, the risk adjusted 30-day mortality was 1.6% for each group.

"Post-discharge care for acute MI patients is a performance measure, and we do track how often these patients are admitted

to the hospital following their discharge," Dr. Vora said. "A big focus of quality improvement is identifying strategies to reduce rehospitalization."

The next step in the research will be to identify the specific barriers to receiving follow-up care for transferred patients, he added, and then "define clear pathways and clear plans following discharge to ensure that these patients receive the care and the follow-up that they need."

The Agency for Healthcare Research and Quality funded this research. Three coauthors reported relevant relationships.

NEW YORK (Reuters Health) - Myocardial infarction (MI) patients who are transferred to another hospital for care are less likely to be followed up and more likely to be readmitted to the hospital, new findings show.

"This group of patients may represent a vulnerable population and we really need to come up with specific strategies to make their post-discharge transition back to their local community as seamless as possible," corresponding author Dr. Amit Vora, of Duke University in Durham, North Carolina, told Reuters Health.

Many patients admitted to their local hospital for acute MI must be transferred to another hospital for care, for example, to receive revascularization, Dr. Vora and his team note in their report, to be published online in Circulation: Cardiovascular Quality and outcomes. Logistical factors may lead to poor communication and coordination when it's time for the patient to be transferred back to their community, they add, which could be particularly problematic for older patients who may have more comorbidity and require closer follow-up after discharge.

To investigate, the researchers looked at outcomes for 39,136 acute MI patients 65 and older who were treated between 2007 and 2010 at 451 hospitals participating in Acute Coronary Treatment and Intervention Outcomes Network Registry-Get With the Guidelines.

Thirty-six percent of patients were transferred to another hospital for acute MI care, traveling a median of 43 miles.Within 30 days of discharge, 69.9% of the transferred patients had received outpatient follow-up, versus 78.2% of direct-arrival patients.

The adjusted risk of readmission for any cause was 14.5% for transferred patients versus 14% for direct-admit patients, while the risk of readmission for cardiovascular causes was 9.5% for

transferred patients and 9.1% for the direct-admit patients.However, the risk adjusted 30-day mortality was 1.6% for each group.

"Post-discharge care for acute MI patients is a performance measure, and we do track how often these patients are admitted

to the hospital following their discharge," Dr. Vora said. "A big focus of quality improvement is identifying strategies to reduce rehospitalization."

The next step in the research will be to identify the specific barriers to receiving follow-up care for transferred patients, he added, and then "define clear pathways and clear plans following discharge to ensure that these patients receive the care and the follow-up that they need."

The Agency for Healthcare Research and Quality funded this research. Three coauthors reported relevant relationships.

NEW YORK (Reuters Health) - Hospital differences in pain management are tied to different patient-reported pain scores after colorectal resection, according to a study from the Michigan Surgical Quality Collaborative (MSQC).

"The best-performing hospitals achieved superior pain control through the use of analgesia regimens that more often used local anesthesia blocks in the operating room,non-steroidal anti-inflammatory drugs, and patient-controlled analgesia rather than intermittent narcotics," said Dr. Scott E. Regenbogen from the University of Michigan, Ann Arbor.

"This suggests that efforts to implement multimodal analgesia regimens may improve pain control in the immediate postoperative period," he told Reuters Health by email.

Despite increasing attention to postoperative pain management, most patients continue to experience severe pain after major surgery, Dr. Regenbogen and colleagues note in Annals of Surgery, online January 7.

The researchers used MSQC data from 52 hospitals to evaluate the extent to which multimodal pain management practices are used after major surgery and how hospitals' perioperative practices might affect patient-reported pain levels in real-world surgical practice. Their study included 7,221 patients who underwent colorectal resection between 2012 and 2014.

Nine hospitals had average adjusted pain scores significantly worse and eight hospitals had average adjusted pain scores significantly better than the overall average. The "best" hospitals were somewhat larger and had higher annual volumes of colorectal resection than the "worst" hospitals.

Patients in hospitals with best pain scores were significantly more likely to receive local anesthesia and epidural anesthesia during the operation and to have patient-controlled analgesia (PCA), nonsteroidal anti-inflammatory drugs (NSAIDs), or a combination of PCA and NSAIDs and significantly less likely to receive intermittent postoperative narcotics, compared with patients in hospitals with worst pain scores.

Hospitals with the lowest pain scores had a significantly higher proportion of operations with a minimally invasive approach than did hospitals with the highest pain scores.

Patients whose operations took place in hospitals in the lowest quartile of pain scores had significantly shorter mean postoperative length of stay and were significantly less likely to have a postoperative complication, emergency department visit, or readmission.

Patient factors contributing to worse pain scores included being younger than 50 (versus age over 75), a woman, black (versus white), a smoker, and uninsured or insured by Medicaid (versus Medicare or privately insured).

"Most likely," the researchers note, "both pain scores and clinical outcomes reflect more global features of the quality of care in hospitals' surgical performance. Thus, hospitals with the most streamlined, high-quality perioperative care pathways experience the best pain scores, as well as improved clinical outcomes."

"Early postoperative analgesia regimens are an essential component of efforts to improve the efficiency and quality of postoperative recovery," Dr. Regenbogen said."Effective pain control, even in the first postoperative day, is associated with reduced postoperative length of stay and fewer major complications and readmissions. Thus, effective multimodal analgesia is an essential component of high-value perioperative care around colorectal surgery."

"This study is hopefully just one example of a growing emphasis on patient-reported outcomes in surgery," Dr.Regenbogen said. "Within a statewide quality collaborative, we have begun to prioritize engagement of patients, in addition to our partnering surgeons, hospitals, and mayors, in efforts to improve surgical care in Michigan. In this study, we used patient-reported pain measures to evaluate quality of care. In the near future, we will elicit patient-reported measures of functional recovery, psychosocial support, and other outcomes to validate the perioperative outcomes we have relied on traditionally. We hope this study will serve as a model for those novel areas of investigation."

Dr. Antoni Sabate from Hospital Universitari de Bellvitge in Barcelona, Spain, who has researched postoperative analgesia told Reuters Health by email, "Pain is largely influenced by magnitude of the surgical procedure, surgical technique (minimally invasive), analgesia protocol (the use of local anesthetic infiltration in open and laparoscopic, the use of epidural in open procedures, implementation of PCA and NSAID in both laparoscopic and open procedures."

NEW YORK (Reuters Health) - Hospital differences in pain management are tied to different patient-reported pain scores after colorectal resection, according to a study from the Michigan Surgical Quality Collaborative (MSQC).

"The best-performing hospitals achieved superior pain control through the use of analgesia regimens that more often used local anesthesia blocks in the operating room,non-steroidal anti-inflammatory drugs, and patient-controlled analgesia rather than intermittent narcotics," said Dr. Scott E. Regenbogen from the University of Michigan, Ann Arbor.

"This suggests that efforts to implement multimodal analgesia regimens may improve pain control in the immediate postoperative period," he told Reuters Health by email.

Despite increasing attention to postoperative pain management, most patients continue to experience severe pain after major surgery, Dr. Regenbogen and colleagues note in Annals of Surgery, online January 7.

The researchers used MSQC data from 52 hospitals to evaluate the extent to which multimodal pain management practices are used after major surgery and how hospitals' perioperative practices might affect patient-reported pain levels in real-world surgical practice. Their study included 7,221 patients who underwent colorectal resection between 2012 and 2014.

Nine hospitals had average adjusted pain scores significantly worse and eight hospitals had average adjusted pain scores significantly better than the overall average. The "best" hospitals were somewhat larger and had higher annual volumes of colorectal resection than the "worst" hospitals.

Patients in hospitals with best pain scores were significantly more likely to receive local anesthesia and epidural anesthesia during the operation and to have patient-controlled analgesia (PCA), nonsteroidal anti-inflammatory drugs (NSAIDs), or a combination of PCA and NSAIDs and significantly less likely to receive intermittent postoperative narcotics, compared with patients in hospitals with worst pain scores.

Hospitals with the lowest pain scores had a significantly higher proportion of operations with a minimally invasive approach than did hospitals with the highest pain scores.

Patients whose operations took place in hospitals in the lowest quartile of pain scores had significantly shorter mean postoperative length of stay and were significantly less likely to have a postoperative complication, emergency department visit, or readmission.

Patient factors contributing to worse pain scores included being younger than 50 (versus age over 75), a woman, black (versus white), a smoker, and uninsured or insured by Medicaid (versus Medicare or privately insured).

"Most likely," the researchers note, "both pain scores and clinical outcomes reflect more global features of the quality of care in hospitals' surgical performance. Thus, hospitals with the most streamlined, high-quality perioperative care pathways experience the best pain scores, as well as improved clinical outcomes."

"Early postoperative analgesia regimens are an essential component of efforts to improve the efficiency and quality of postoperative recovery," Dr. Regenbogen said."Effective pain control, even in the first postoperative day, is associated with reduced postoperative length of stay and fewer major complications and readmissions. Thus, effective multimodal analgesia is an essential component of high-value perioperative care around colorectal surgery."

"This study is hopefully just one example of a growing emphasis on patient-reported outcomes in surgery," Dr.Regenbogen said. "Within a statewide quality collaborative, we have begun to prioritize engagement of patients, in addition to our partnering surgeons, hospitals, and mayors, in efforts to improve surgical care in Michigan. In this study, we used patient-reported pain measures to evaluate quality of care. In the near future, we will elicit patient-reported measures of functional recovery, psychosocial support, and other outcomes to validate the perioperative outcomes we have relied on traditionally. We hope this study will serve as a model for those novel areas of investigation."

Dr. Antoni Sabate from Hospital Universitari de Bellvitge in Barcelona, Spain, who has researched postoperative analgesia told Reuters Health by email, "Pain is largely influenced by magnitude of the surgical procedure, surgical technique (minimally invasive), analgesia protocol (the use of local anesthetic infiltration in open and laparoscopic, the use of epidural in open procedures, implementation of PCA and NSAID in both laparoscopic and open procedures."

NEW YORK (Reuters Health) - Hospital differences in pain management are tied to different patient-reported pain scores after colorectal resection, according to a study from the Michigan Surgical Quality Collaborative (MSQC).

"The best-performing hospitals achieved superior pain control through the use of analgesia regimens that more often used local anesthesia blocks in the operating room,non-steroidal anti-inflammatory drugs, and patient-controlled analgesia rather than intermittent narcotics," said Dr. Scott E. Regenbogen from the University of Michigan, Ann Arbor.

"This suggests that efforts to implement multimodal analgesia regimens may improve pain control in the immediate postoperative period," he told Reuters Health by email.

Despite increasing attention to postoperative pain management, most patients continue to experience severe pain after major surgery, Dr. Regenbogen and colleagues note in Annals of Surgery, online January 7.

The researchers used MSQC data from 52 hospitals to evaluate the extent to which multimodal pain management practices are used after major surgery and how hospitals' perioperative practices might affect patient-reported pain levels in real-world surgical practice. Their study included 7,221 patients who underwent colorectal resection between 2012 and 2014.

Nine hospitals had average adjusted pain scores significantly worse and eight hospitals had average adjusted pain scores significantly better than the overall average. The "best" hospitals were somewhat larger and had higher annual volumes of colorectal resection than the "worst" hospitals.

Patients in hospitals with best pain scores were significantly more likely to receive local anesthesia and epidural anesthesia during the operation and to have patient-controlled analgesia (PCA), nonsteroidal anti-inflammatory drugs (NSAIDs), or a combination of PCA and NSAIDs and significantly less likely to receive intermittent postoperative narcotics, compared with patients in hospitals with worst pain scores.

Hospitals with the lowest pain scores had a significantly higher proportion of operations with a minimally invasive approach than did hospitals with the highest pain scores.

Patients whose operations took place in hospitals in the lowest quartile of pain scores had significantly shorter mean postoperative length of stay and were significantly less likely to have a postoperative complication, emergency department visit, or readmission.

Patient factors contributing to worse pain scores included being younger than 50 (versus age over 75), a woman, black (versus white), a smoker, and uninsured or insured by Medicaid (versus Medicare or privately insured).

"Most likely," the researchers note, "both pain scores and clinical outcomes reflect more global features of the quality of care in hospitals' surgical performance. Thus, hospitals with the most streamlined, high-quality perioperative care pathways experience the best pain scores, as well as improved clinical outcomes."

"Early postoperative analgesia regimens are an essential component of efforts to improve the efficiency and quality of postoperative recovery," Dr. Regenbogen said."Effective pain control, even in the first postoperative day, is associated with reduced postoperative length of stay and fewer major complications and readmissions. Thus, effective multimodal analgesia is an essential component of high-value perioperative care around colorectal surgery."

"This study is hopefully just one example of a growing emphasis on patient-reported outcomes in surgery," Dr.Regenbogen said. "Within a statewide quality collaborative, we have begun to prioritize engagement of patients, in addition to our partnering surgeons, hospitals, and mayors, in efforts to improve surgical care in Michigan. In this study, we used patient-reported pain measures to evaluate quality of care. In the near future, we will elicit patient-reported measures of functional recovery, psychosocial support, and other outcomes to validate the perioperative outcomes we have relied on traditionally. We hope this study will serve as a model for those novel areas of investigation."

Dr. Antoni Sabate from Hospital Universitari de Bellvitge in Barcelona, Spain, who has researched postoperative analgesia told Reuters Health by email, "Pain is largely influenced by magnitude of the surgical procedure, surgical technique (minimally invasive), analgesia protocol (the use of local anesthetic infiltration in open and laparoscopic, the use of epidural in open procedures, implementation of PCA and NSAID in both laparoscopic and open procedures."

(Reuters Health) - The causes of acute myocardial infarction(MI) and the warning symptoms that can signal the need for immediate medical attention are different in women than in men, according to a scientific statement issued today by the American Heart Association.

When women don't recognize this, they may suffer worse outcomes, a fate that is even more likely in black and Hispanic women, according to the AHA.

The AHA published its first comprehensive statement on gender differences in acute MI patients in Circulation, January 25.

"Women seem to do worse for several reasons," said Dr. Laxmi Mehta, the lead author of the recommendations and the director of women's cardiovascular health at Ohio State University in Columbus.

Importantly, people don't realize that while both sexes may experience chest pain before or during a heart attack, women maybe more likely to have unusual symptoms instead, such as shortness of breath, nausea or vomiting, and back or neck pain.

Then, when they do get to a hospital, women may be less likely than men to receive medications that help to prevent clots, decrease the heart's workload and lower blood pressure or cholesterol.

"There is a lot at stake for women when there is a delay in treatment or lack of adherence to recommended therapies," Mehta added by email. "Women face higher rates of being readmitted to the hospital, heart failure and death."

Biology is also part of the problem. Even though both women and men suffer MI caused by blockages in the main arteries leading to the heart, the way the clots develop may differ, according to the scientific statement.

Men tend to have a more "classic" type of blockage where plaque ruptures off the artery wall, forms a blood clot and causes a complete halt of blood flow through the artery to the heart, said Dr. Sheila Sahni, chief fellow in cardiovascular disease at the David Geffen School of Medicine at the University of California Los Angeles.

"Women, more often, tend to have a plaque erosion where smaller pieces of plaque break off, become exposed and cause the formation of smaller blood clots which may or may not cause total occlusions all at once, leading to a more subtle presentation," Sahni, who wasn't involved in the study, said by email.

In addition, women tend to be about a decade older than men when they suffer acute MI, potentially making them frailer and more likely to suffer from other health problems such as diabetes that can make their treatment more complicated, Sahni added.

Risk factors also differ by gender, with hypertension more strongly associated with MI in women than in men. For young women with diabetes, the risk for heart disease is four to five times higher than it would be for a similar young man.

Race, too, is an issue. Compared to white women, black women have a higher incidence of MI in all age categories and young black women have greater odds of dying before they leave the hospital. Black and Hispanic women are also more likely to have

heart-related risk factors such as diabetes, obesity and hypertension at the time of their MI.

Once a heart attack begins, the best way for women to minimize damage is to get help quickly, said Dr. Leslie Cho, director of the women's cardiovascular center at the Cleveland Clinic and Clinic in Ohio.

"Time is muscle," Cho, who wasn't involved in the study, said by email. "If women are diagnosed and treated later in the course of the heart attack, they can suffer from irreversible heart damage."

(Reuters Health) - The causes of acute myocardial infarction(MI) and the warning symptoms that can signal the need for immediate medical attention are different in women than in men, according to a scientific statement issued today by the American Heart Association.

When women don't recognize this, they may suffer worse outcomes, a fate that is even more likely in black and Hispanic women, according to the AHA.

The AHA published its first comprehensive statement on gender differences in acute MI patients in Circulation, January 25.

"Women seem to do worse for several reasons," said Dr. Laxmi Mehta, the lead author of the recommendations and the director of women's cardiovascular health at Ohio State University in Columbus.

Importantly, people don't realize that while both sexes may experience chest pain before or during a heart attack, women maybe more likely to have unusual symptoms instead, such as shortness of breath, nausea or vomiting, and back or neck pain.

Then, when they do get to a hospital, women may be less likely than men to receive medications that help to prevent clots, decrease the heart's workload and lower blood pressure or cholesterol.

"There is a lot at stake for women when there is a delay in treatment or lack of adherence to recommended therapies," Mehta added by email. "Women face higher rates of being readmitted to the hospital, heart failure and death."

Biology is also part of the problem. Even though both women and men suffer MI caused by blockages in the main arteries leading to the heart, the way the clots develop may differ, according to the scientific statement.

Men tend to have a more "classic" type of blockage where plaque ruptures off the artery wall, forms a blood clot and causes a complete halt of blood flow through the artery to the heart, said Dr. Sheila Sahni, chief fellow in cardiovascular disease at the David Geffen School of Medicine at the University of California Los Angeles.

"Women, more often, tend to have a plaque erosion where smaller pieces of plaque break off, become exposed and cause the formation of smaller blood clots which may or may not cause total occlusions all at once, leading to a more subtle presentation," Sahni, who wasn't involved in the study, said by email.

In addition, women tend to be about a decade older than men when they suffer acute MI, potentially making them frailer and more likely to suffer from other health problems such as diabetes that can make their treatment more complicated, Sahni added.

Risk factors also differ by gender, with hypertension more strongly associated with MI in women than in men. For young women with diabetes, the risk for heart disease is four to five times higher than it would be for a similar young man.

Race, too, is an issue. Compared to white women, black women have a higher incidence of MI in all age categories and young black women have greater odds of dying before they leave the hospital. Black and Hispanic women are also more likely to have

heart-related risk factors such as diabetes, obesity and hypertension at the time of their MI.

Once a heart attack begins, the best way for women to minimize damage is to get help quickly, said Dr. Leslie Cho, director of the women's cardiovascular center at the Cleveland Clinic and Clinic in Ohio.

"Time is muscle," Cho, who wasn't involved in the study, said by email. "If women are diagnosed and treated later in the course of the heart attack, they can suffer from irreversible heart damage."

(Reuters Health) - The causes of acute myocardial infarction(MI) and the warning symptoms that can signal the need for immediate medical attention are different in women than in men, according to a scientific statement issued today by the American Heart Association.

When women don't recognize this, they may suffer worse outcomes, a fate that is even more likely in black and Hispanic women, according to the AHA.

The AHA published its first comprehensive statement on gender differences in acute MI patients in Circulation, January 25.

"Women seem to do worse for several reasons," said Dr. Laxmi Mehta, the lead author of the recommendations and the director of women's cardiovascular health at Ohio State University in Columbus.

Importantly, people don't realize that while both sexes may experience chest pain before or during a heart attack, women maybe more likely to have unusual symptoms instead, such as shortness of breath, nausea or vomiting, and back or neck pain.

Then, when they do get to a hospital, women may be less likely than men to receive medications that help to prevent clots, decrease the heart's workload and lower blood pressure or cholesterol.

"There is a lot at stake for women when there is a delay in treatment or lack of adherence to recommended therapies," Mehta added by email. "Women face higher rates of being readmitted to the hospital, heart failure and death."

Biology is also part of the problem. Even though both women and men suffer MI caused by blockages in the main arteries leading to the heart, the way the clots develop may differ, according to the scientific statement.

Men tend to have a more "classic" type of blockage where plaque ruptures off the artery wall, forms a blood clot and causes a complete halt of blood flow through the artery to the heart, said Dr. Sheila Sahni, chief fellow in cardiovascular disease at the David Geffen School of Medicine at the University of California Los Angeles.

"Women, more often, tend to have a plaque erosion where smaller pieces of plaque break off, become exposed and cause the formation of smaller blood clots which may or may not cause total occlusions all at once, leading to a more subtle presentation," Sahni, who wasn't involved in the study, said by email.

In addition, women tend to be about a decade older than men when they suffer acute MI, potentially making them frailer and more likely to suffer from other health problems such as diabetes that can make their treatment more complicated, Sahni added.

Risk factors also differ by gender, with hypertension more strongly associated with MI in women than in men. For young women with diabetes, the risk for heart disease is four to five times higher than it would be for a similar young man.

Race, too, is an issue. Compared to white women, black women have a higher incidence of MI in all age categories and young black women have greater odds of dying before they leave the hospital. Black and Hispanic women are also more likely to have

heart-related risk factors such as diabetes, obesity and hypertension at the time of their MI.

Once a heart attack begins, the best way for women to minimize damage is to get help quickly, said Dr. Leslie Cho, director of the women's cardiovascular center at the Cleveland Clinic and Clinic in Ohio.

"Time is muscle," Cho, who wasn't involved in the study, said by email. "If women are diagnosed and treated later in the course of the heart attack, they can suffer from irreversible heart damage."

NEW YORK (Reuters Health) - Inpatient dermatology consultations for skin disorders are associated with improved diagnostic accuracy and faster intervention, researchers have

found.

Information about the impact of hospitalist dermatology consultative services is limited, Dr. Daniela Kroshinsky from Massachusetts General Hospital in Boston and colleagues note in JAMA  Dermatology, online January 13.

To learn more, the team conducted a cross-sectional study of data from dermatology consult teams at four academic medical centers in the U.S. Full-time inpatient dermatologists with resident teams performed a total of 1,661 inpatient dermatology consultations within 24 to 48 hours of request over 12 months from 2008 to 2009.

All final diagnoses were based on clinical history, examination findings, and laboratory testing. Each service (primary team) that asked for a dermatology consult provided its presumptive diagnosis at the time of its request.

The most common primary teams were Medicine (47%), followed by Surgery (15%), Intensive Care Units (12%), and Hematology-Oncology (9%). The most commonly undiagnosed or misdiagnosed conditions by the primary teams were cellulitis, leg ulcerations, and viral infections. The majority of primary team preliminary diagnoses included rash/unknown (n=814), followed by cellulitis/abscess (n=115), and drug rash (n=111). The majority of primary diagnoses by dermatologists included drug rash (n=292; 18%), psoriasis/eczema (n=170; 10%), and benign neoplasm (n=168; 10%).

The dermatologists identified additional cutaneous issues in 298 (18%) of consults; diagnosis was confirmed by biopsy in 667 (40%) patients. Overall, dermatology consultation changed the final diagnosis in 71% of consultation requests.

Just under a third of the patients were admitted to the hospitals because of their skin conditions. In the remaining cases, the dermatologic issues were found incidentally or developed during hospitalization.

In 40% of cases, dermatology-specific evaluation and treatment recommendations were carried out in a single visit; 29% required one follow-up evaluation and 16% required two.

"This is the first multicenter national study to define the nature of dermatologic issues presenting to academic medical centers and to demonstrate the impact dermatologists have on improving the correct diagnosis of patients with skin issues,"Dr. Kroshinsky told Reuters Health by email.

Hospitalist dermatology is an important and effective subset of dermatology and hospital medicine, she said.

"Ideally," Dr. Kroshinsky added, "hospitals would have access to a dermatologist in real-time or via teledermatology."

NEW YORK (Reuters Health) - Inpatient dermatology consultations for skin disorders are associated with improved diagnostic accuracy and faster intervention, researchers have

found.

Information about the impact of hospitalist dermatology consultative services is limited, Dr. Daniela Kroshinsky from Massachusetts General Hospital in Boston and colleagues note in JAMA  Dermatology, online January 13.

To learn more, the team conducted a cross-sectional study of data from dermatology consult teams at four academic medical centers in the U.S. Full-time inpatient dermatologists with resident teams performed a total of 1,661 inpatient dermatology consultations within 24 to 48 hours of request over 12 months from 2008 to 2009.

All final diagnoses were based on clinical history, examination findings, and laboratory testing. Each service (primary team) that asked for a dermatology consult provided its presumptive diagnosis at the time of its request.

The most common primary teams were Medicine (47%), followed by Surgery (15%), Intensive Care Units (12%), and Hematology-Oncology (9%). The most commonly undiagnosed or misdiagnosed conditions by the primary teams were cellulitis, leg ulcerations, and viral infections. The majority of primary team preliminary diagnoses included rash/unknown (n=814), followed by cellulitis/abscess (n=115), and drug rash (n=111). The majority of primary diagnoses by dermatologists included drug rash (n=292; 18%), psoriasis/eczema (n=170; 10%), and benign neoplasm (n=168; 10%).

The dermatologists identified additional cutaneous issues in 298 (18%) of consults; diagnosis was confirmed by biopsy in 667 (40%) patients. Overall, dermatology consultation changed the final diagnosis in 71% of consultation requests.

Just under a third of the patients were admitted to the hospitals because of their skin conditions. In the remaining cases, the dermatologic issues were found incidentally or developed during hospitalization.

In 40% of cases, dermatology-specific evaluation and treatment recommendations were carried out in a single visit; 29% required one follow-up evaluation and 16% required two.

"This is the first multicenter national study to define the nature of dermatologic issues presenting to academic medical centers and to demonstrate the impact dermatologists have on improving the correct diagnosis of patients with skin issues,"Dr. Kroshinsky told Reuters Health by email.

Hospitalist dermatology is an important and effective subset of dermatology and hospital medicine, she said.

"Ideally," Dr. Kroshinsky added, "hospitals would have access to a dermatologist in real-time or via teledermatology."

NEW YORK (Reuters Health) - Inpatient dermatology consultations for skin disorders are associated with improved diagnostic accuracy and faster intervention, researchers have

found.

Information about the impact of hospitalist dermatology consultative services is limited, Dr. Daniela Kroshinsky from Massachusetts General Hospital in Boston and colleagues note in JAMA  Dermatology, online January 13.

To learn more, the team conducted a cross-sectional study of data from dermatology consult teams at four academic medical centers in the U.S. Full-time inpatient dermatologists with resident teams performed a total of 1,661 inpatient dermatology consultations within 24 to 48 hours of request over 12 months from 2008 to 2009.

All final diagnoses were based on clinical history, examination findings, and laboratory testing. Each service (primary team) that asked for a dermatology consult provided its presumptive diagnosis at the time of its request.

The most common primary teams were Medicine (47%), followed by Surgery (15%), Intensive Care Units (12%), and Hematology-Oncology (9%). The most commonly undiagnosed or misdiagnosed conditions by the primary teams were cellulitis, leg ulcerations, and viral infections. The majority of primary team preliminary diagnoses included rash/unknown (n=814), followed by cellulitis/abscess (n=115), and drug rash (n=111). The majority of primary diagnoses by dermatologists included drug rash (n=292; 18%), psoriasis/eczema (n=170; 10%), and benign neoplasm (n=168; 10%).

The dermatologists identified additional cutaneous issues in 298 (18%) of consults; diagnosis was confirmed by biopsy in 667 (40%) patients. Overall, dermatology consultation changed the final diagnosis in 71% of consultation requests.

Just under a third of the patients were admitted to the hospitals because of their skin conditions. In the remaining cases, the dermatologic issues were found incidentally or developed during hospitalization.

In 40% of cases, dermatology-specific evaluation and treatment recommendations were carried out in a single visit; 29% required one follow-up evaluation and 16% required two.

"This is the first multicenter national study to define the nature of dermatologic issues presenting to academic medical centers and to demonstrate the impact dermatologists have on improving the correct diagnosis of patients with skin issues,"Dr. Kroshinsky told Reuters Health by email.

Hospitalist dermatology is an important and effective subset of dermatology and hospital medicine, she said.

"Ideally," Dr. Kroshinsky added, "hospitals would have access to a dermatologist in real-time or via teledermatology."

NEW YORK - Diagnostic codes from administrative claims data underestimate cardiovascular disease event rates, researchers report.

"Increasingly, the diagnostic codes from administrative claims data are being used to measure clinical outcomes," Dr. Bruce M. Psaty from the University of Washington, Seattle, said by email. "The methods of using only claims data as outcomes nonetheless influence the results. Methods that seek to avoid misclassification tend to underestimate event rates, and methods that attempt to include all events tend to include misclassified events such as non-event hospitalizations as part of the outcome."

Dr. Psaty's team used data from the Cardiovascular Health Study (CHS) to evaluate the degree of both misclassification and underestimation of event rates for cardiovascular disease outcomes identified solely from claims data compared with those identified through active surveillance.

An ICD9 code of 410 in the first position had a 90.6% positive predictive value (PPV) for MI, but this code only identified 53.8% of the incident MIs ascertained by active surveillance. Inclusion of this code as a secondary diagnosis identified an additional 16.6% of MI events.

Similarly, main stroke codes in the first position had an 80.4% PPV for stroke, but identified only 63.8% of the incident stroke events. For heart failure, main diagnostic codes had a high PPV of 93.2%, but identified only 27.2% of heart failure events.

Estimates of disease incidence differed markedly according to whether the incidence rates were determined by CHS surveillance, a first-position diagnostic code, or a diagnostic code in any position.

In general, misclassified events in the administrative claims data appeared to have little effect on the magnitude of associations for most cardiovascular disease risk factors, the researchers report in Circulation, online Nov. 4.

"No study is perfect, and some incomplete identification of events in a study is common," Dr. Psaty explained. "The effect depends on both the type of study and the degree of incompleteness. In a clinical trial, if there is no bias, the relative-risk comparison between the two groups remains valid even if some of the events were missed. If, on the other hand, the goal is the development of a model for the prediction of event rates to decide on whether to start a cholesterol lowering therapy, the incomplete identification of events introduces a bias in the model that is directly related to the degree of incompleteness in the identification of events."

"Events data collection should be appropriate for the study," Dr. Psaty concluded. "Published studies need to provide sufficient detail so that readers can judge whether the methods were indeed fit for purpose."

NEW YORK - Diagnostic codes from administrative claims data underestimate cardiovascular disease event rates, researchers report.

"Increasingly, the diagnostic codes from administrative claims data are being used to measure clinical outcomes," Dr. Bruce M. Psaty from the University of Washington, Seattle, said by email. "The methods of using only claims data as outcomes nonetheless influence the results. Methods that seek to avoid misclassification tend to underestimate event rates, and methods that attempt to include all events tend to include misclassified events such as non-event hospitalizations as part of the outcome."

Dr. Psaty's team used data from the Cardiovascular Health Study (CHS) to evaluate the degree of both misclassification and underestimation of event rates for cardiovascular disease outcomes identified solely from claims data compared with those identified through active surveillance.

An ICD9 code of 410 in the first position had a 90.6% positive predictive value (PPV) for MI, but this code only identified 53.8% of the incident MIs ascertained by active surveillance. Inclusion of this code as a secondary diagnosis identified an additional 16.6% of MI events.

Similarly, main stroke codes in the first position had an 80.4% PPV for stroke, but identified only 63.8% of the incident stroke events. For heart failure, main diagnostic codes had a high PPV of 93.2%, but identified only 27.2% of heart failure events.

Estimates of disease incidence differed markedly according to whether the incidence rates were determined by CHS surveillance, a first-position diagnostic code, or a diagnostic code in any position.

In general, misclassified events in the administrative claims data appeared to have little effect on the magnitude of associations for most cardiovascular disease risk factors, the researchers report in Circulation, online Nov. 4.

"No study is perfect, and some incomplete identification of events in a study is common," Dr. Psaty explained. "The effect depends on both the type of study and the degree of incompleteness. In a clinical trial, if there is no bias, the relative-risk comparison between the two groups remains valid even if some of the events were missed. If, on the other hand, the goal is the development of a model for the prediction of event rates to decide on whether to start a cholesterol lowering therapy, the incomplete identification of events introduces a bias in the model that is directly related to the degree of incompleteness in the identification of events."

"Events data collection should be appropriate for the study," Dr. Psaty concluded. "Published studies need to provide sufficient detail so that readers can judge whether the methods were indeed fit for purpose."

NEW YORK - Diagnostic codes from administrative claims data underestimate cardiovascular disease event rates, researchers report.

"Increasingly, the diagnostic codes from administrative claims data are being used to measure clinical outcomes," Dr. Bruce M. Psaty from the University of Washington, Seattle, said by email. "The methods of using only claims data as outcomes nonetheless influence the results. Methods that seek to avoid misclassification tend to underestimate event rates, and methods that attempt to include all events tend to include misclassified events such as non-event hospitalizations as part of the outcome."

Dr. Psaty's team used data from the Cardiovascular Health Study (CHS) to evaluate the degree of both misclassification and underestimation of event rates for cardiovascular disease outcomes identified solely from claims data compared with those identified through active surveillance.

An ICD9 code of 410 in the first position had a 90.6% positive predictive value (PPV) for MI, but this code only identified 53.8% of the incident MIs ascertained by active surveillance. Inclusion of this code as a secondary diagnosis identified an additional 16.6% of MI events.

Similarly, main stroke codes in the first position had an 80.4% PPV for stroke, but identified only 63.8% of the incident stroke events. For heart failure, main diagnostic codes had a high PPV of 93.2%, but identified only 27.2% of heart failure events.

Estimates of disease incidence differed markedly according to whether the incidence rates were determined by CHS surveillance, a first-position diagnostic code, or a diagnostic code in any position.

In general, misclassified events in the administrative claims data appeared to have little effect on the magnitude of associations for most cardiovascular disease risk factors, the researchers report in Circulation, online Nov. 4.

"No study is perfect, and some incomplete identification of events in a study is common," Dr. Psaty explained. "The effect depends on both the type of study and the degree of incompleteness. In a clinical trial, if there is no bias, the relative-risk comparison between the two groups remains valid even if some of the events were missed. If, on the other hand, the goal is the development of a model for the prediction of event rates to decide on whether to start a cholesterol lowering therapy, the incomplete identification of events introduces a bias in the model that is directly related to the degree of incompleteness in the identification of events."

"Events data collection should be appropriate for the study," Dr. Psaty concluded. "Published studies need to provide sufficient detail so that readers can judge whether the methods were indeed fit for purpose."

NEW YORK - Medicare Advantage plans might not be meeting the needs of patients requiring the costliest and most complex levels of care, a new study suggests.

Between 2010 and 2011, such patients were more likely to switch from Medicare Advantage plans to traditional Medicare, rather than vice versa, researchers found.

The results suggest people should carefully consider all the benefits, payments, and quality measures before enrolling in Medicare Advantage plans, said lead author Dr. Momotazur Rahman of Brown University in Providence, R.I.

Unlike traditional Medicare, which is the U.S. health insurance program for the elderly and disabled, Medicare Advantage is offered by private insurance companies. While the plans cover all services provided under traditional Medicare, Advantage plans may also include added services like eye and dental coverage. They may also charge different out-of pocket costs and offer access to different sets of providers.

At the beginning of each month, the government pays Medicare Advantage companies a lump sum to cover enrollees' expenses - with higher sums for high-risk patients.

Rahman and his colleagues write in Health Affairs that lump sums encourage companies to keep healthcare costs low. But there's been some concern that companies were maximizing profits by enrolling healthier people, whereas traditional Medicare is obligated to enroll all comers.

According to the authors of the new study, legislation in 2003 aimed to address those concerns, and research suggests it helped close the gap in deaths and healthcare use and spending between people in the two types of plans.

Other studies, however, have suggested Advantage plans were still overpaid under the new system and switching between plans was limited to those needing the most care.

The researchers analyzed data on more than 36,000 Medicare beneficiaries, about a quarter of whom were enrolled in Medicare Advantage plans, to see how many switched from one type of plan to the other over the course of the year.

Overall, there was little difference, with 4 percent of traditional Medicare beneficiaries switching, compared to 5 percent of those in Medicare Advantage plans.

But there was a difference when the researchers looked at people requiring complex care - with more switching away from Medicare Advantage plans than from traditional Medicare.

For example, 17 percent of people in nursing homes for long stays switched from Medicare Advantage to traditional Medicare between 2010 and 2011, while only 3 percent moved in the opposite direction.

Also, 8 percent of people receiving home healthcare switched from Medicare Advantage during that time, compared to 3 percent switching from traditional Medicare.

The results were more exaggerated for people enrolled in both Medicare and Medicaid. Those people are allowed to switch anytime and usually use increasingly expensive care, Dr. Rahman said.

It's not clear why people needing higher levels of care are more likely to switch out of Medicare Advantage plans, said Dr. Gretchen Jacobson, associate director with the Kaiser Family Foundation's Program on Medicare Policy in Washington, D.C.

For example, it could be due to limited provider networks, unused extra benefits, or prescription drug needs, said Dr. Jacobson, who wasn't involved with the new study.

However, she said, it's important to point out that the vast majority of people remain in their chosen programs.

"Most people are not changing when they make an initial decision about their coverage, but this is an area that's ripe for more research," she said.

A representative of America's Health Insurance Plans (AHIP) also stressed that the study only looked at one point in time, and changes for Medicare Advantage plans were adopted since that period.

"More specifically, enrollment in Medicare Advantage has continued to increase year after year as program continues to offer coordinated care that leads to better outcomes for seniors and those with chronic conditions," said AHIP's Clare Krusing.

"If the type of disenrollment that was highlighted in this study was as pervasive as the authors suggest, there would be much greater evidence that beneficiaries were leaving the program in significant numbers," she said.

NEW YORK - Medicare Advantage plans might not be meeting the needs of patients requiring the costliest and most complex levels of care, a new study suggests.

Between 2010 and 2011, such patients were more likely to switch from Medicare Advantage plans to traditional Medicare, rather than vice versa, researchers found.

The results suggest people should carefully consider all the benefits, payments, and quality measures before enrolling in Medicare Advantage plans, said lead author Dr. Momotazur Rahman of Brown University in Providence, R.I.

Unlike traditional Medicare, which is the U.S. health insurance program for the elderly and disabled, Medicare Advantage is offered by private insurance companies. While the plans cover all services provided under traditional Medicare, Advantage plans may also include added services like eye and dental coverage. They may also charge different out-of pocket costs and offer access to different sets of providers.

At the beginning of each month, the government pays Medicare Advantage companies a lump sum to cover enrollees' expenses - with higher sums for high-risk patients.

Rahman and his colleagues write in Health Affairs that lump sums encourage companies to keep healthcare costs low. But there's been some concern that companies were maximizing profits by enrolling healthier people, whereas traditional Medicare is obligated to enroll all comers.

According to the authors of the new study, legislation in 2003 aimed to address those concerns, and research suggests it helped close the gap in deaths and healthcare use and spending between people in the two types of plans.

Other studies, however, have suggested Advantage plans were still overpaid under the new system and switching between plans was limited to those needing the most care.

The researchers analyzed data on more than 36,000 Medicare beneficiaries, about a quarter of whom were enrolled in Medicare Advantage plans, to see how many switched from one type of plan to the other over the course of the year.

Overall, there was little difference, with 4 percent of traditional Medicare beneficiaries switching, compared to 5 percent of those in Medicare Advantage plans.

But there was a difference when the researchers looked at people requiring complex care - with more switching away from Medicare Advantage plans than from traditional Medicare.

For example, 17 percent of people in nursing homes for long stays switched from Medicare Advantage to traditional Medicare between 2010 and 2011, while only 3 percent moved in the opposite direction.

Also, 8 percent of people receiving home healthcare switched from Medicare Advantage during that time, compared to 3 percent switching from traditional Medicare.

The results were more exaggerated for people enrolled in both Medicare and Medicaid. Those people are allowed to switch anytime and usually use increasingly expensive care, Dr. Rahman said.

It's not clear why people needing higher levels of care are more likely to switch out of Medicare Advantage plans, said Dr. Gretchen Jacobson, associate director with the Kaiser Family Foundation's Program on Medicare Policy in Washington, D.C.

For example, it could be due to limited provider networks, unused extra benefits, or prescription drug needs, said Dr. Jacobson, who wasn't involved with the new study.

However, she said, it's important to point out that the vast majority of people remain in their chosen programs.

"Most people are not changing when they make an initial decision about their coverage, but this is an area that's ripe for more research," she said.

A representative of America's Health Insurance Plans (AHIP) also stressed that the study only looked at one point in time, and changes for Medicare Advantage plans were adopted since that period.

"More specifically, enrollment in Medicare Advantage has continued to increase year after year as program continues to offer coordinated care that leads to better outcomes for seniors and those with chronic conditions," said AHIP's Clare Krusing.

"If the type of disenrollment that was highlighted in this study was as pervasive as the authors suggest, there would be much greater evidence that beneficiaries were leaving the program in significant numbers," she said.

NEW YORK - Medicare Advantage plans might not be meeting the needs of patients requiring the costliest and most complex levels of care, a new study suggests.

Between 2010 and 2011, such patients were more likely to switch from Medicare Advantage plans to traditional Medicare, rather than vice versa, researchers found.

The results suggest people should carefully consider all the benefits, payments, and quality measures before enrolling in Medicare Advantage plans, said lead author Dr. Momotazur Rahman of Brown University in Providence, R.I.

Unlike traditional Medicare, which is the U.S. health insurance program for the elderly and disabled, Medicare Advantage is offered by private insurance companies. While the plans cover all services provided under traditional Medicare, Advantage plans may also include added services like eye and dental coverage. They may also charge different out-of pocket costs and offer access to different sets of providers.

At the beginning of each month, the government pays Medicare Advantage companies a lump sum to cover enrollees' expenses - with higher sums for high-risk patients.

Rahman and his colleagues write in Health Affairs that lump sums encourage companies to keep healthcare costs low. But there's been some concern that companies were maximizing profits by enrolling healthier people, whereas traditional Medicare is obligated to enroll all comers.

According to the authors of the new study, legislation in 2003 aimed to address those concerns, and research suggests it helped close the gap in deaths and healthcare use and spending between people in the two types of plans.

Other studies, however, have suggested Advantage plans were still overpaid under the new system and switching between plans was limited to those needing the most care.

The researchers analyzed data on more than 36,000 Medicare beneficiaries, about a quarter of whom were enrolled in Medicare Advantage plans, to see how many switched from one type of plan to the other over the course of the year.

Overall, there was little difference, with 4 percent of traditional Medicare beneficiaries switching, compared to 5 percent of those in Medicare Advantage plans.

But there was a difference when the researchers looked at people requiring complex care - with more switching away from Medicare Advantage plans than from traditional Medicare.

For example, 17 percent of people in nursing homes for long stays switched from Medicare Advantage to traditional Medicare between 2010 and 2011, while only 3 percent moved in the opposite direction.

Also, 8 percent of people receiving home healthcare switched from Medicare Advantage during that time, compared to 3 percent switching from traditional Medicare.

The results were more exaggerated for people enrolled in both Medicare and Medicaid. Those people are allowed to switch anytime and usually use increasingly expensive care, Dr. Rahman said.

It's not clear why people needing higher levels of care are more likely to switch out of Medicare Advantage plans, said Dr. Gretchen Jacobson, associate director with the Kaiser Family Foundation's Program on Medicare Policy in Washington, D.C.

For example, it could be due to limited provider networks, unused extra benefits, or prescription drug needs, said Dr. Jacobson, who wasn't involved with the new study.

However, she said, it's important to point out that the vast majority of people remain in their chosen programs.

"Most people are not changing when they make an initial decision about their coverage, but this is an area that's ripe for more research," she said.

A representative of America's Health Insurance Plans (AHIP) also stressed that the study only looked at one point in time, and changes for Medicare Advantage plans were adopted since that period.

"More specifically, enrollment in Medicare Advantage has continued to increase year after year as program continues to offer coordinated care that leads to better outcomes for seniors and those with chronic conditions," said AHIP's Clare Krusing.

"If the type of disenrollment that was highlighted in this study was as pervasive as the authors suggest, there would be much greater evidence that beneficiaries were leaving the program in significant numbers," she said.

NEW YORK - While the new International Classification of Diseases, Tenth Revision, Clinical

Modification (ICD-10-CM) codes offer greater diagnostic precision, their implementation will require training of clinicians, coders, and other staff to minimize payment denials or delays from both public and private payers.

Brian Outland and colleagues from the American College of Physicians in Washington, D.C., outline some of the promises and challenges of ICD-10-CM implementation in a report online Sept. 22 in Annals of Internal Medicine.

Although completed and endorsed by the World Health Assembly in 1990, ICD-10-CM's implementation date has repeatedly been delayed, and was scheduled to take effect on Oct. 1.

The authors suggest that "the newer coding system will produce data that will indicate the clinical trajectory and other factors that will enable the data to be used in meaningful ways to better understand complications, design robust algorithms for clinical decision support, and track outcomes. Having these details built into the codes will decrease the need for health care providers to include supporting documentation with claims."

The new ICD-10-CM alphanumeric codes will contain as many as seven characters that specify categories, subcategories, laterality, severity and other features.

The use of codes that are not specific enough can result in payment denials or delays, so practices will need to keep current on payer reimbursement policies to ensure the reporting of ICD-10-CM codes that support reimbursement, the authors note.

The cost for the training of clinicians and staffs will depend on practice size, specialty, the method of training, current documentation quality, and technology readiness and availability.

Dr. Susan H. Fenton from UTHealth School of Biomedical Informatics in Houston, Texas, said by email, "One of the thoughts I cannot get away from is that the U.S. is trying to manage a 21st-century, rapidly evolving healthcare system with a 1970s technology. I can think of little else in healthcare that has remained as static since the 1970s."

"The diagnostic system added lots of codes, but the basic structure is the same," she said.

"Certainly, with more detail such as laterality, as well as first encounter, subsequent encounter, and sequelae, it will be much easier to track care for specific conditions across providers," Dr. Fenton said. "I think the issue of claims denials will have to play out over time."

Resources and tools from the Centers for Medicare & Medicaid Services (CMS) can be found online at www.roadto10.org.

The American College of Physicians also has helpful information available at www.acponline.org/ICD10.

Outland did not respond to a request for comment.

NEW YORK - While the new International Classification of Diseases, Tenth Revision, Clinical

Modification (ICD-10-CM) codes offer greater diagnostic precision, their implementation will require training of clinicians, coders, and other staff to minimize payment denials or delays from both public and private payers.

Brian Outland and colleagues from the American College of Physicians in Washington, D.C., outline some of the promises and challenges of ICD-10-CM implementation in a report online Sept. 22 in Annals of Internal Medicine.

Although completed and endorsed by the World Health Assembly in 1990, ICD-10-CM's implementation date has repeatedly been delayed, and was scheduled to take effect on Oct. 1.

The authors suggest that "the newer coding system will produce data that will indicate the clinical trajectory and other factors that will enable the data to be used in meaningful ways to better understand complications, design robust algorithms for clinical decision support, and track outcomes. Having these details built into the codes will decrease the need for health care providers to include supporting documentation with claims."

The new ICD-10-CM alphanumeric codes will contain as many as seven characters that specify categories, subcategories, laterality, severity and other features.

The use of codes that are not specific enough can result in payment denials or delays, so practices will need to keep current on payer reimbursement policies to ensure the reporting of ICD-10-CM codes that support reimbursement, the authors note.

The cost for the training of clinicians and staffs will depend on practice size, specialty, the method of training, current documentation quality, and technology readiness and availability.

Dr. Susan H. Fenton from UTHealth School of Biomedical Informatics in Houston, Texas, said by email, "One of the thoughts I cannot get away from is that the U.S. is trying to manage a 21st-century, rapidly evolving healthcare system with a 1970s technology. I can think of little else in healthcare that has remained as static since the 1970s."

"The diagnostic system added lots of codes, but the basic structure is the same," she said.

"Certainly, with more detail such as laterality, as well as first encounter, subsequent encounter, and sequelae, it will be much easier to track care for specific conditions across providers," Dr. Fenton said. "I think the issue of claims denials will have to play out over time."

Resources and tools from the Centers for Medicare & Medicaid Services (CMS) can be found online at www.roadto10.org.

The American College of Physicians also has helpful information available at www.acponline.org/ICD10.

Outland did not respond to a request for comment.

NEW YORK - While the new International Classification of Diseases, Tenth Revision, Clinical

Modification (ICD-10-CM) codes offer greater diagnostic precision, their implementation will require training of clinicians, coders, and other staff to minimize payment denials or delays from both public and private payers.

Brian Outland and colleagues from the American College of Physicians in Washington, D.C., outline some of the promises and challenges of ICD-10-CM implementation in a report online Sept. 22 in Annals of Internal Medicine.

Although completed and endorsed by the World Health Assembly in 1990, ICD-10-CM's implementation date has repeatedly been delayed, and was scheduled to take effect on Oct. 1.

The authors suggest that "the newer coding system will produce data that will indicate the clinical trajectory and other factors that will enable the data to be used in meaningful ways to better understand complications, design robust algorithms for clinical decision support, and track outcomes. Having these details built into the codes will decrease the need for health care providers to include supporting documentation with claims."

The new ICD-10-CM alphanumeric codes will contain as many as seven characters that specify categories, subcategories, laterality, severity and other features.

The use of codes that are not specific enough can result in payment denials or delays, so practices will need to keep current on payer reimbursement policies to ensure the reporting of ICD-10-CM codes that support reimbursement, the authors note.

The cost for the training of clinicians and staffs will depend on practice size, specialty, the method of training, current documentation quality, and technology readiness and availability.

Dr. Susan H. Fenton from UTHealth School of Biomedical Informatics in Houston, Texas, said by email, "One of the thoughts I cannot get away from is that the U.S. is trying to manage a 21st-century, rapidly evolving healthcare system with a 1970s technology. I can think of little else in healthcare that has remained as static since the 1970s."

"The diagnostic system added lots of codes, but the basic structure is the same," she said.

"Certainly, with more detail such as laterality, as well as first encounter, subsequent encounter, and sequelae, it will be much easier to track care for specific conditions across providers," Dr. Fenton said. "I think the issue of claims denials will have to play out over time."

Resources and tools from the Centers for Medicare & Medicaid Services (CMS) can be found online at www.roadto10.org.

The American College of Physicians also has helpful information available at www.acponline.org/ICD10.

Outland did not respond to a request for comment.

NEW YORK - Elderly patients with pneumonia whose need for intensive care unit (ICU) admission is uncertain actually fare better in the ICU than on the general medical ward, a new study suggests.

"Although our results should be confirmed with a randomized trial, clinicians should be aware that many patients who are borderline candidates for ICU admission may benefit from care provided in an ICU," Dr. Colin Cooke, from the University of Michigan, Ann Arbor, said.

To gauge the relationship between ICU admission and outcomes for elderly patients with pneumonia, the researchers took a look back at more than 1.1 million Medicare beneficiaries admitted to nearly 3,000 acute care hospitals with pneumonia from 2010 to 2012.

The team compared 30-day mortality between patients admitted to the ICU and those admitted solely to the hospital ward. They used instrumental variable analysis to account for selection bias inherent in this comparison.

Thirty percent of the cohort was admitted to the ICU. Patients living less than 3.3 miles of a hospital with high ICU admission were more apt to be admitted to the ICU than their peers living farther away, according to a report in the September 22/29 issue of JAMA.

For the 13 percent of patients whose ICU admission was deemed discretionary, ICU admission was associated with a significant reduction in 30-day mortality (14.8 percent for ICU care vs. 20.5 percent for general ward care, p<0.02).

There were no statistically significant differences in total costs or total Medicare payments between groups, "suggesting that ICU admission can save lives for lower-risk patients, and can do so at similar cost," note the authors of a linked editorial.

This study provides "important empirical evidence that ICU admission can benefit low-risk patients," write Dr. Ian J. Barbash and Dr. Jeremy M. Kahn, of the University of Pittsburgh School of Medicine in Pennsylvania.

The findings, they add, "argue against active efforts to reduce ICU admissions through triage guidelines or bed supply reductions, at least for older patients with pneumonia. In the current health care system, more judicious use of the ICU may well lead to higher mortality in some patient populations." Dr. Cooke said, "It would be premature for our study to warrant significant changes in clinical practice. Nevertheless, our results are intriguing and suggest that there indeed is a population of patients with pneumonia who may not be hospitalized in an ICU but who would otherwise benefit from ICU-level care. The sooner we can identify this group of patients clinically, the sooner we can begin the confirmatory studies."

NEW YORK - Elderly patients with pneumonia whose need for intensive care unit (ICU) admission is uncertain actually fare better in the ICU than on the general medical ward, a new study suggests.

"Although our results should be confirmed with a randomized trial, clinicians should be aware that many patients who are borderline candidates for ICU admission may benefit from care provided in an ICU," Dr. Colin Cooke, from the University of Michigan, Ann Arbor, said.

To gauge the relationship between ICU admission and outcomes for elderly patients with pneumonia, the researchers took a look back at more than 1.1 million Medicare beneficiaries admitted to nearly 3,000 acute care hospitals with pneumonia from 2010 to 2012.

The team compared 30-day mortality between patients admitted to the ICU and those admitted solely to the hospital ward. They used instrumental variable analysis to account for selection bias inherent in this comparison.

Thirty percent of the cohort was admitted to the ICU. Patients living less than 3.3 miles of a hospital with high ICU admission were more apt to be admitted to the ICU than their peers living farther away, according to a report in the September 22/29 issue of JAMA.

For the 13 percent of patients whose ICU admission was deemed discretionary, ICU admission was associated with a significant reduction in 30-day mortality (14.8 percent for ICU care vs. 20.5 percent for general ward care, p<0.02).

There were no statistically significant differences in total costs or total Medicare payments between groups, "suggesting that ICU admission can save lives for lower-risk patients, and can do so at similar cost," note the authors of a linked editorial.

This study provides "important empirical evidence that ICU admission can benefit low-risk patients," write Dr. Ian J. Barbash and Dr. Jeremy M. Kahn, of the University of Pittsburgh School of Medicine in Pennsylvania.

The findings, they add, "argue against active efforts to reduce ICU admissions through triage guidelines or bed supply reductions, at least for older patients with pneumonia. In the current health care system, more judicious use of the ICU may well lead to higher mortality in some patient populations." Dr. Cooke said, "It would be premature for our study to warrant significant changes in clinical practice. Nevertheless, our results are intriguing and suggest that there indeed is a population of patients with pneumonia who may not be hospitalized in an ICU but who would otherwise benefit from ICU-level care. The sooner we can identify this group of patients clinically, the sooner we can begin the confirmatory studies."

NEW YORK - Elderly patients with pneumonia whose need for intensive care unit (ICU) admission is uncertain actually fare better in the ICU than on the general medical ward, a new study suggests.

"Although our results should be confirmed with a randomized trial, clinicians should be aware that many patients who are borderline candidates for ICU admission may benefit from care provided in an ICU," Dr. Colin Cooke, from the University of Michigan, Ann Arbor, said.

To gauge the relationship between ICU admission and outcomes for elderly patients with pneumonia, the researchers took a look back at more than 1.1 million Medicare beneficiaries admitted to nearly 3,000 acute care hospitals with pneumonia from 2010 to 2012.

The team compared 30-day mortality between patients admitted to the ICU and those admitted solely to the hospital ward. They used instrumental variable analysis to account for selection bias inherent in this comparison.

Thirty percent of the cohort was admitted to the ICU. Patients living less than 3.3 miles of a hospital with high ICU admission were more apt to be admitted to the ICU than their peers living farther away, according to a report in the September 22/29 issue of JAMA.

For the 13 percent of patients whose ICU admission was deemed discretionary, ICU admission was associated with a significant reduction in 30-day mortality (14.8 percent for ICU care vs. 20.5 percent for general ward care, p<0.02).

There were no statistically significant differences in total costs or total Medicare payments between groups, "suggesting that ICU admission can save lives for lower-risk patients, and can do so at similar cost," note the authors of a linked editorial.

This study provides "important empirical evidence that ICU admission can benefit low-risk patients," write Dr. Ian J. Barbash and Dr. Jeremy M. Kahn, of the University of Pittsburgh School of Medicine in Pennsylvania.

The findings, they add, "argue against active efforts to reduce ICU admissions through triage guidelines or bed supply reductions, at least for older patients with pneumonia. In the current health care system, more judicious use of the ICU may well lead to higher mortality in some patient populations." Dr. Cooke said, "It would be premature for our study to warrant significant changes in clinical practice. Nevertheless, our results are intriguing and suggest that there indeed is a population of patients with pneumonia who may not be hospitalized in an ICU but who would otherwise benefit from ICU-level care. The sooner we can identify this group of patients clinically, the sooner we can begin the confirmatory studies."

NEW YORK - Catheter ablation is favored for the management of most forms of supraventricular tachycardia (SVT) in adults, according to revised guidelines from the American College of Cardiology/American Heart Association/Heart Rhythm Society (ACC/AHA/HRS).

SVT affects 2.25 in 1000 individuals in the general population, with about 89,000 new cases of paroxysmal SVT (PSVT) per year. Women are twice as likely as men and individuals older than 65 are more than five times as likely as younger people to develop PSVT.

To provide a contemporary guideline for managing adults with all types of SVT except atrial fibrillation, ACC/AHA/HRS have now updated their 2003 guidelines.

Included are recommendations for managing sinus tachyarrhythmias, nonsinus focal atrial tachycardia and multifocal atrial tachycardia (MAT), atrioventricular nodal reentrant tachycardia (AVNRT), manifest and concealed accessory pathways, atrial flutter, and junctional tachycardia.

"Despite a 12-year gap in the update for these guidelines, there have been very few advances in antiarrhythmic drug therapy to offer patients with SVT," Dr. Gregory F. Michaud, director of the Center for Advanced Management of Atrial Fibrillation at Brigham and Women's Hospital in Boston, said by email.

"Catheter ablation has taken a stronger foothold in the chronic treatment of SVT and as such many physicians and patients are opting for invasive therapy earlier in the course of therapy," said Dr. Michaud, who wasn't involved in the guidelines.

The guidelines recommend vagal maneuvers, various drugs, and/or cardioversion as acute treatments, depending on the specific cause of SVT.

For most forms of symptomatic SVT, including those of unknown mechanism, the guidelines recommend electrophysiological (EP) studies and catheter ablation as definitive treatment for patients willing to undergo them, especially if medical therapy is ineffective.

Cardiac mapping is performed during EP studies to identify the site of origin of the arrhythmia or areas of critical conduction to allow targeting of ablation.

"One exception is inappropriate sinus tachycardia (IST) for which a more effective drug, ivabradine, is now available in the United States," Dr. Michaud said. "Catheter ablation is generally ineffective for IST patients."

Besides evaluation and treatment of possible reversible causes of IST, the guidelines recommend ivabradine, beta blockers, or their combination.

"SVT is generally not a life-threatening condition and treatment is based on eliminating symptoms and improving patient quality of life," Dr. Michaud explained. "However, physicians should be aware of three conditions associated with SVT that may be serious. First, sudden death is associated with the WPW (Wolff-Parkinson-White) syndrome and these patients, even if asymptomatic, should be referred to a cardiac electrophysiologist to consider management options."

He continued, "Second, SVT can cause cardiomyopathy and heart failure when incessant, even if the patient is asymptomatic. These patients should also be referred to a cardiac electrophysiologist to consider definitive therapy.

Third, patients with atrial flutter should be considered for oral anticoagulation to prevent stroke using the CHADS-Vasc risk scoring system, just as you would for patients with atrial fibrillation."

Dr. Michaud added, "Putting aside cost as an issue, there is significant regional variability in the accessibility of electrophysiologists or cardiologists with arrhythmia expertise. In my area, for instance, electrophysiologists are plentiful, and patients with SVT are often sent to us directly for further evaluation and treatment. Furthermore, training in arrhythmia management has become the purview of clinical cardiac electrophysiology, and many recently trained cardiologists are not as comfortable as their predecessors in managing patients with SVT."

The full report appears in the September 23 Journal of the American College of Cardiology online and was copublished in Circulation and Heart Rhythm.

Dr. Richard L. Page and Dr. Jose A. Joglar, chair and vice chair of the writing committee, did not respond to a request for comments.

NEW YORK - Catheter ablation is favored for the management of most forms of supraventricular tachycardia (SVT) in adults, according to revised guidelines from the American College of Cardiology/American Heart Association/Heart Rhythm Society (ACC/AHA/HRS).

SVT affects 2.25 in 1000 individuals in the general population, with about 89,000 new cases of paroxysmal SVT (PSVT) per year. Women are twice as likely as men and individuals older than 65 are more than five times as likely as younger people to develop PSVT.

To provide a contemporary guideline for managing adults with all types of SVT except atrial fibrillation, ACC/AHA/HRS have now updated their 2003 guidelines.

Included are recommendations for managing sinus tachyarrhythmias, nonsinus focal atrial tachycardia and multifocal atrial tachycardia (MAT), atrioventricular nodal reentrant tachycardia (AVNRT), manifest and concealed accessory pathways, atrial flutter, and junctional tachycardia.

"Despite a 12-year gap in the update for these guidelines, there have been very few advances in antiarrhythmic drug therapy to offer patients with SVT," Dr. Gregory F. Michaud, director of the Center for Advanced Management of Atrial Fibrillation at Brigham and Women's Hospital in Boston, said by email.

"Catheter ablation has taken a stronger foothold in the chronic treatment of SVT and as such many physicians and patients are opting for invasive therapy earlier in the course of therapy," said Dr. Michaud, who wasn't involved in the guidelines.

The guidelines recommend vagal maneuvers, various drugs, and/or cardioversion as acute treatments, depending on the specific cause of SVT.

For most forms of symptomatic SVT, including those of unknown mechanism, the guidelines recommend electrophysiological (EP) studies and catheter ablation as definitive treatment for patients willing to undergo them, especially if medical therapy is ineffective.

Cardiac mapping is performed during EP studies to identify the site of origin of the arrhythmia or areas of critical conduction to allow targeting of ablation.

"One exception is inappropriate sinus tachycardia (IST) for which a more effective drug, ivabradine, is now available in the United States," Dr. Michaud said. "Catheter ablation is generally ineffective for IST patients."

Besides evaluation and treatment of possible reversible causes of IST, the guidelines recommend ivabradine, beta blockers, or their combination.

"SVT is generally not a life-threatening condition and treatment is based on eliminating symptoms and improving patient quality of life," Dr. Michaud explained. "However, physicians should be aware of three conditions associated with SVT that may be serious. First, sudden death is associated with the WPW (Wolff-Parkinson-White) syndrome and these patients, even if asymptomatic, should be referred to a cardiac electrophysiologist to consider management options."

He continued, "Second, SVT can cause cardiomyopathy and heart failure when incessant, even if the patient is asymptomatic. These patients should also be referred to a cardiac electrophysiologist to consider definitive therapy.

Third, patients with atrial flutter should be considered for oral anticoagulation to prevent stroke using the CHADS-Vasc risk scoring system, just as you would for patients with atrial fibrillation."

Dr. Michaud added, "Putting aside cost as an issue, there is significant regional variability in the accessibility of electrophysiologists or cardiologists with arrhythmia expertise. In my area, for instance, electrophysiologists are plentiful, and patients with SVT are often sent to us directly for further evaluation and treatment. Furthermore, training in arrhythmia management has become the purview of clinical cardiac electrophysiology, and many recently trained cardiologists are not as comfortable as their predecessors in managing patients with SVT."

The full report appears in the September 23 Journal of the American College of Cardiology online and was copublished in Circulation and Heart Rhythm.

Dr. Richard L. Page and Dr. Jose A. Joglar, chair and vice chair of the writing committee, did not respond to a request for comments.

NEW YORK - Catheter ablation is favored for the management of most forms of supraventricular tachycardia (SVT) in adults, according to revised guidelines from the American College of Cardiology/American Heart Association/Heart Rhythm Society (ACC/AHA/HRS).

SVT affects 2.25 in 1000 individuals in the general population, with about 89,000 new cases of paroxysmal SVT (PSVT) per year. Women are twice as likely as men and individuals older than 65 are more than five times as likely as younger people to develop PSVT.

To provide a contemporary guideline for managing adults with all types of SVT except atrial fibrillation, ACC/AHA/HRS have now updated their 2003 guidelines.

Included are recommendations for managing sinus tachyarrhythmias, nonsinus focal atrial tachycardia and multifocal atrial tachycardia (MAT), atrioventricular nodal reentrant tachycardia (AVNRT), manifest and concealed accessory pathways, atrial flutter, and junctional tachycardia.

"Despite a 12-year gap in the update for these guidelines, there have been very few advances in antiarrhythmic drug therapy to offer patients with SVT," Dr. Gregory F. Michaud, director of the Center for Advanced Management of Atrial Fibrillation at Brigham and Women's Hospital in Boston, said by email.

"Catheter ablation has taken a stronger foothold in the chronic treatment of SVT and as such many physicians and patients are opting for invasive therapy earlier in the course of therapy," said Dr. Michaud, who wasn't involved in the guidelines.

The guidelines recommend vagal maneuvers, various drugs, and/or cardioversion as acute treatments, depending on the specific cause of SVT.

For most forms of symptomatic SVT, including those of unknown mechanism, the guidelines recommend electrophysiological (EP) studies and catheter ablation as definitive treatment for patients willing to undergo them, especially if medical therapy is ineffective.

Cardiac mapping is performed during EP studies to identify the site of origin of the arrhythmia or areas of critical conduction to allow targeting of ablation.

"One exception is inappropriate sinus tachycardia (IST) for which a more effective drug, ivabradine, is now available in the United States," Dr. Michaud said. "Catheter ablation is generally ineffective for IST patients."

Besides evaluation and treatment of possible reversible causes of IST, the guidelines recommend ivabradine, beta blockers, or their combination.

"SVT is generally not a life-threatening condition and treatment is based on eliminating symptoms and improving patient quality of life," Dr. Michaud explained. "However, physicians should be aware of three conditions associated with SVT that may be serious. First, sudden death is associated with the WPW (Wolff-Parkinson-White) syndrome and these patients, even if asymptomatic, should be referred to a cardiac electrophysiologist to consider management options."

He continued, "Second, SVT can cause cardiomyopathy and heart failure when incessant, even if the patient is asymptomatic. These patients should also be referred to a cardiac electrophysiologist to consider definitive therapy.

Third, patients with atrial flutter should be considered for oral anticoagulation to prevent stroke using the CHADS-Vasc risk scoring system, just as you would for patients with atrial fibrillation."

Dr. Michaud added, "Putting aside cost as an issue, there is significant regional variability in the accessibility of electrophysiologists or cardiologists with arrhythmia expertise. In my area, for instance, electrophysiologists are plentiful, and patients with SVT are often sent to us directly for further evaluation and treatment. Furthermore, training in arrhythmia management has become the purview of clinical cardiac electrophysiology, and many recently trained cardiologists are not as comfortable as their predecessors in managing patients with SVT."

The full report appears in the September 23 Journal of the American College of Cardiology online and was copublished in Circulation and Heart Rhythm.

Dr. Richard L. Page and Dr. Jose A. Joglar, chair and vice chair of the writing committee, did not respond to a request for comments.